義大醫院第六版處方集增修版 ( 第一次公告 ) 公告日期 : 102/12/11 102.10.01 p.150 原處方集內容 Klean-Prep C 6 Unknown 4 Klean-Prep 68.6g/sachet <KKLEAN> Each sachet contains: Polyethylene glycol 3350......59 g Sodium sulfate anhydrous......5.685 g Sodium bicarbonate.........1.685 g Sodium chloride.........1.465 g Potassium chloride......0.7425 g Aspartame.........0.0494 g Bowel preparation before colonoscopy, colonic surgery, radiological examination and other related procedures 第十八次藥政會決議新藥, 並刪除 Klean-Prep 102.10.02 p.73 Docetaxel D 4 Unknown 1 Tyxan 20mg/ <CDOCET1> Tyxan 80mg/2ml/vial <CDOCET2> Breast cancer, non-small cell lung cancer, gastric cancer, head- neck cancer, prostate cancer 廠商告知藥品規格及外觀變更 102.10.04 p.163 Rivaroxaban C 4 Unsafe 1 Xarelto 10mg/FC. tab <KRIVARO> Postoperative thromboprophylaxis in patients who have undergone hip or knee replacement surgery Arthroplasty of knee Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 2 weeks Repair of hip Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 5 weeks ALT and AST increase, anemia, nausea, bleeding 1. 服用本品須監測出血徵狀 2. 本品含乳糖, 患有罕見遺傳疾病, 包含乳糖不耐症 乳糖酶缺乏症或葡萄糖 - 半乳糖吸收不良者不應服用本藥 修正後處方集內容 GI Klean powder C 6 Unknown 4 GI Klean powder 68.6g/sachet <KKLEAN1> Each sachet contains: Polyethylene glycol 3350......59 g Sodium sulfate anhydrous......5.685 g Sodium bicarbonate.........1.685 g Sodium chloride.........1.465 g Potassium chloride......0.7425 g Aspartame.........0.0494 g Bowel preparation before colonoscopy, colonic surgery, radiological examination and other related procedures Docetaxel D 4 Unknown 1 Tynen 20mg/1ml/vial <CDOCET1> Tynen 80mg/4ml/vial<CDOCET2> Breast cancer, non-small cell lung cancer, gastric cancer, head- neck cancer, prostate cancer Rivaroxaban C 4 Unsafe 1 Xarelto 10mg/FC. tab <KRIVARO> Xarelto 15mg/FC. tab <KRIVAR2> Xarelto 20mg/FC. tab <KRIVAR1> 10mg: Postoperative thromboprophylaxis in patients who have undergone hip or knee replacement surgery 15 and 20mg: nonvalvular atrial fibrillation and treatment of deep vein thrombosis and pulmonary embolism Arthroplasty of knee Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 2 weeks Repair of hip Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 5 weeks Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation PO 15~20mg qn; max: 20mg/day Treatment of deep vein thrombosis and prevention of recurrent DVT and pulmonary embolism PO 15mg bid for 21days (max: 30mg/day) then 20mg qd (max: 20mg/day) ALT and AST increase, anemia, nausea, bleeding 1. 服用本品須監測出血徵狀 2. 本品含乳糖, 患有罕見遺傳疾病, 包含乳糖不耐症 乳糖酶缺乏症或葡萄糖 - 半乳糖吸收
第十八次藥政會決議新藥 102.10.07 p.148 Metoclopramide B 1 Safe 4 Primperan 10mg/2ml/amp <CMETOCL> Promeran 3.84mg /tab <KMETOC1> Aswell syrup 60mg/60ml/bot <KMETOC3> 學名藥比價, 更換廠商 102.10.11 p.143 Famotidine B 4 Safe 1 Fadin Lyo-injection 20mg/vial <CFAMOTI> Quimadine 20mg/tab <KFAMOTI> 廠商來函告知藥品商品名變更 102.10.18 p.109 Irbesartan D 4 Unknown 1 Aprovel 150mg/tab <KIRBESA> Hypertension Children 6-12 yrs: PO initial 75mg qd; max: 150mg/day Adults: PO initial 150mg qd; max: 300mg/day Diarrhea, dyspepsia, upper respiratory infection, headache, fatigue 第十二次藥政會決議新藥, 並刪除 Irbesartan 150mg/tab 102.10.23 p.213 Sulfinpyrazone Unknown 1 Sulfin 100mg/tab <KSULFIN> Gout and gouty arthritis PO 200-400mg/day; max: 800mg/day Stomach pains, nausea, vomiting, exacerbation of ulcers, mild granulocytopenia 1.Patients with a history of healed peptic ulcer 2. 需依腎功能調整劑量 Acute attack of gout, blood dyscrasias 第十七次藥政會決議新藥, 並刪除 Sulfinpyrazone 不良者不應服用本藥 3. 外科手術與介入治療 : 應於該治療的至少 24 小時前停用 Xarelto 4. 硬腦膜外導管應在服用本品最後一劑後的 18 小時之後再移除, 導管取出後的 6 個小時之後才可再服用本品, 如發生外傷性穿刺, 則給藥時間應延後 24 小時 Metoclopramide B 1 Safe 4 Promeran 9.08mg/ 2ml/amp <CMETOCL> Promeran 3.84mg /tab <KMETOC1> Aswell syrup 60mg/60ml/bot <KMETOC3> Famotidine B 4 Safe 1 Fadin Lyo-injection 20mg/vial <CFAMOTI> Famotidine 20mg/tab <KFAMOTI> Irbesartan D 4 Unknown 1 Aprovel 150mg/tab <KIRBESA> Aprovel 300mg/tab <KIRBES1> Hypertension, diabetic nephropathy Hypertension Adults: PO initial 150mg qd; max: 300mg/day Diabetic nephropathy Adult: PO initial 150mg qd, target maintenance does 300mg qd Diarrhea, dyspepsia, upper respiratory infection, headache, fatigue Febuxostat C 4 Unknown 1 Feburic 80mg/tab <KFEBUXO> Chronic management of hyperuricemia in patients with gout PO initial 40mg qd, increased to 80mg qd if sua 6mg/dl after 2 weeks Liver enzymes abnormal, rash, nausea, arthralgia, gout attack(during initial treatment) 開始使用後, 由於血清尿酸濃度改變導致尿酸鹽從組織沉積移轉, 痛風可能會發作, 故建議併用 NSAIDs 或 Colchicine 以預防痛風發作, 預防性治療效益達 6 個月 ; 治療過程若痛風發作無需停用 Feburic 正在使用 Azathioprine 或 Mercaptopurine 的患者 無症狀高尿酸血症禁用
102.10.28 p.151 Lactulose B 4 Unknown 1 Lactul 500ml/bot, 1ml: Lactulose 666mg <KLACTUL> 學名藥比價, 更換規格 102.10.30 p.28, 30 Drug name Combivir Lamivuding 150mg+Zidovudine 1 tab bid 300mg/tab < KCOMBI> 60kg 400mg qd Didanosine (DDI) <60kg 250mg qd Kivexa Lamivudine (3-TC) Stavudine (d4t) Videx EC 250mg/cap <KDIDANO> Videx EC 400mg/cap <KDIDAN2 > Abacavir 600mg+Lamivudine 300mg/tab<KKIVEXA> 3-TC 150mg/tab <KLAMIV2 > Zerit 30mg/cap <KSTAVU1> Zerit 40mg/cap <KSTAVU2> > 40 kg, 1 tab qd 3mon-16yrs:4mg/kg bid Adults: 150mg bid 60kg: 40mg q12h; <60kg: 30mg q12h Lactulose B 4 Unknown 1 Lactul 300ml/bot, 1ml: Lactulose 666mg <KLACTUL> Drug name Kaletra Lopinavir 200mg+Ritonavir 2 tab bid 50mg/ tab <KKALET1> Atazanavir Darunavir Ritonavir Reyataz 200mg/cap <KATAZAN> Reyataz 150mg/cap <KATAZA1> Prezista 600mg/tab <KDARUNA> Prezista 400mg/tab <KDARUN1> 第十一次藥政會決議新藥 Atazanavir 150mg/cap, 並刪除 Stavudine 40mg/cap 102.10.31 p.286 Bethanechol C 4 Unknown 1 Mesacol 25mg/tab <KBETHAN> Neurogenic bladder atony with retention, postoperative nonobstructive urinary retention Urinary retention PO 10-50 mg/day tid-qid AC, max: 50 mg Abdominal cramps, diarrhea, excessive lacrimation, miosis, flushing of skin 處方集內文勘誤 102.11.01 p.229 102.11.04 p.16, 122 Selegiline C 4 Unknown 1 Seginine 5mg/tab <KSELEGI> 學名藥比價, 更換廠商 Gentamicin C 6 Unknown 1 Gentamycin 80mg/2ml/vial<CGENTA2> 參閱 p.16 Garamycin cream 0.1%, 15g/tube <WGARAMY> Oftalmolosa oint 0.3%, 5g/tube<WGENTA3> 參閱 p.253 Norvir 100mg/soft gelatin cap <KRITONA > For treatment-naïve and therapy-experienced patients Reyataz 300mg + Ritonavir 100mg qd For treatment-naïve patients who are unable tolerate Ritonavir Reyataz 400mg qd 600-800mg bid concomitantly with ritonavir 100mg Adult: initial 300mg bid, then increase by 100 mg bid every 2 to 3 days, max 600mg bid 2yrs Children: initial, 250 mg/m(2) bid, then increase by 50 mg/m(2) bid every 2 to 3 days, maintenance dose of 350 to 400 mg/m(2); max: 600mg bid Bethanechol C 4 Unknown 1 Mesacol 25mg/tab <KBETHAN> Neurogenic bladder atony with retention, postoperative nonobstructive urinary retention Urinary retention PO 10-50 mg/day tid-qid AC, max: 50 mg Abdominal cramps, diarrhea, excessive lacrimation, miosis, flushing of skin Selegiline C 4 Unknown 1 Parkryl 5mg/tab < KSELEGI> Gentamicin C 6 Unknown 1 Gentamycin 80mg/2ml/vial<CGENTA2> 參閱 p.16 Gentamycin cream 0.1%, 15g/tube <WGARAMY> Oftalmolosa oint 0.3%, 5g/tube<WGENTA3> 參閱 p.253
102.11.11 p.286 102.11.22 p.203 Gentamicin oph sol'n 0.3%,5ml/bot<WGENTA2> 參閱 p.253 Gentamicin oph sol'n 0.3%,5ml/bot<WGENTA2> 參閱 p.253 原廠商供貨不穩, 更換廠商 第十三次藥政會決議新藥 Glipizide C 4 Unknown 1 Glidiab 5mg/tab <KGLIPIZ> Oxybutynin B 4 Unknown 4 Oxbu 5mg/ER tab < KOXYBU1> Smptoms associated with overactive uninhibited neurogenic or reflex neurogenic bladder (eg, urgency, frequency, leakage, urge incontinence, dysuria) PO initial 5mg qd, dose may be increased weekly in 5mg increments; max: 30mg/day Xerostomia, constipation, headache, dizziness, somnolence Precausions 1. 需整粒吞服, 不能咀嚼 分開或壓碎 2. 藥物含在一個無吸收性的外殼內, 外殼會自身體排除, 故若於糞便內發現類似錠劑的東西, 無需擔心 3. 使用本品可能產生昏沉 ( 嗜睡 ) 或視覺模糊, 故駕駛或使用機械須小心 Glipizide C 4 Unknown 1 Glipizide 5mg/tab <KGLIPIZ> 102.11.25 p.283 102.11.25 p.57 廠商告知藥品商品名變更 Tadalafil B 4 Unknown 1 Cialis 20mg/tab <KTADALA> Erectile dysfunction Starting dose: 10mg, no more than once daily, 1 hr before sexual activity; may increase to 20mg Headache, flushing, abnormal vision, nasal congestion, dyspepsia 1.Onset: 30-45 min, duration: 36 hrs 2. 若服用本品不建議使用 α 1 adrenergic blocker 3. 本品不建議每日服用 1.Concurrent use of nitrates (eg. nitroglycerin) 2. 嚴重心血管疾病 ( 如 : 近 90 天有心肌梗塞 未受控制的心律不整等 ) 第十八次藥政會決議新藥 Cyclophosphamide D 4 Unsafe 1 Syklofosfamid 500mg/vial <CCYCL02> Tadalafil B 4 Unknown 1 Cialis 20mg/tab <KTADALA> Cialis 5mg/tab <KTADAL1> Erectile dysfunction 20mg: Initial 10mg, no more than once daily, 1hr before sexual activity; may increase to 20mg 5mg: 2.5mg qd (at the same time), may increase to 5mg qd base on efficacy and tolerability Headache, flushing, abnormal vision, nasal congestion, dyspepsia Precauti 1. 20mg Onset: 30-45 min, duration: 36 hrs 2. 若服用本品不建議使用 α 1 adrenergic blocker 3. 易造成輕度或暫時性血壓降低 4. 高劑量 (10mg or 20mg) 適合於性行為前使用, 但不建議每日服用, 故對於需頻繁使用 ( 每週至少二次 ) 的病患, 經醫師評估後可改每天一次最低劑量 (2.5mg or 5mg) 的治療方式 1.Concurrent use of nitrates (eg. nitroglycerin) 2. 嚴重心血管疾病 ( 如 : 近 90 天有心肌梗塞 未受控制的心律不整等 ) Cyclophosphamide D 4 Unsafe 1 Syklofosfamid 500mg/vial <CCYCL02>
102.11.29 p.289 102.11.29 p.10, 279 疫苗種類 p.82 Leukemias, lymphoma, multiple myeloma IV 40-50mg/kg for 2-5 days or 10-15mg/kg every 7-10 days or 3-5 mg/kg twice weekly Alopecia, gastrointestinal disturbances, hemorrhagic cystitis, leukopenia 需依肝腎功能調整劑量 原廠商停產, 更換廠商 Spironolactone C 4 Safe 1 Dosage Form Spiron 25mg/tab <KSPIRON> 原廠商健保價調整為零, 故更換廠商 Midazolam D 4 Unknown 1 Uzolam 5mg/ml/amp <CMIDA01> Midatin 15mg/3ml/amp <CMIDA02> Effective for anesthesia induction sedation Induction of anesthesia Unpremedication IV 0.3-0.35mg/kg over 20-30 sec; max: 15mg Premedication IV 0.15-0.2mg/kg; max: 20mg Preoperative sedation : 0.03-0.3mg/kg; max:15mg (Uzolam 禁用 ) Hiccoughs, excessive somnolence, headache, respiratory arrest 1. 本品可使用 NS, D5W, D10W 稀釋, 混合比例為 100-1000ml 加 15mg midazolam 2. 稀釋後溶液, 室溫下可保存 24 小時或在 5 下存放 3 天 Contraindication 不可與鹼性溶液混合, 在 sodium bicarbonate 中會產生沉澱 原廠商停產, 更換廠商 適合年齡 本院品項 B 型肝炎免疫球蛋白出生 24 小時內 Hepatitis B immune globulin(hbig) HyperHep B S/D B 型肝炎疫苗第一劑出生滿 3-5 天 Hepatitis B vaccine Endoxan 50mg/tab <KCYCLOP> Breast cancer, leukemias, lymphoma, multiple myeloma, mycosis fungoides, neuroblastoma, ovarian cancer, retinoblastoma,nephrotic syndrome in children IV 40-50mg/kg for 2-5 days or 10-15mg/kg every 7-10 days or 3-5 mg/kg twice weekly PO 1-5mg/kg/day Alopecia, gastrointestinal disturbances, hemorrhagic cystitis, leukopenia 1. Further dilutions in D5W or NS is stable for 24hrs at room temperature and 6 days at refrigeration. 2. 需依肝腎功能調整劑量 Spironolactone C 4 Safe 1 Dosage Form Aldactin 25mg/tab <KSPIRON> Midazolam D 4 Unknown 1 Midazo 5mg/ml/amp <CMIDA01> Midatin 15mg/3ml/amp <CMIDA02> Effective for anesthesia induction sedation Induction of anesthesia Unpremedication: IV 0.3-0.35mg/kg over 20-30 sec; max: 0.6mg/kg Premedication: IV 0.15-0.2mg/kg ICU sedation IV 0.03-0.3mg/kg; max:15mg Preoperative sedation 60 歲以下 : 0.07-0.1mg/kg 60 歲以上 衰弱及慢性病患 : 0.025-0.05mg/kg, usual dose 2-3mg 小孩 : 0.08-0.2mg/kg Hiccoughs, excessive somnolence, headache, respiratory arrest 1. 本品可使用 NS, D5W, D10W 稀釋, 混合比例為 100-1000ml 加 15mg midazolam 2. 稀釋後溶液, 室溫下可保存 24 小時或在 5 下存放 3 天 Contraindication 不可與鹼性溶液混合, 在 sodium bicarbonate 中會產生沉澱 Dosage Forms < 藥品代碼 > <CHEPAT9> 20mcg/ml/vial
第二劑第三劑卡介苗第一劑追加白喉 百日咳百日咳 破傷風 不活化小兒追加麻痺混合疫苗白喉 破傷風破傷風 百日咳百日咳 小兒麻痺症及侵襲性 b 型流行性感冒嗜血桿菌疫苗 出生滿一個月出生滿六個月出生 24 小時後國小六年級普查測驗陰性之學童 將進入國小就讀且滿 5 歲以上之兒童 出生滿二個月出生滿四個月出生滿六個月出生滿 18 個月 Engerix-B <CHEPAT7> Children: 10mcg/dose B.C.G vaccine BCG vaccine Diphtheria, Tetanus, Pertussis and Polio vaccine Adacel - polio DPTa and Polio and Haemophilus influenzae type b conjugate vaccine Pediacel(DTaP5-IPV+Hib) 麻疹疫苗出生滿九個月 Measles vaccine (MV) Rouvax 德國麻疹混合疫苗 腮腺炎腮腺炎 麻疹 出生滿一年三個月 Measles, Mumps and 日本腦炎 處方集內文勘誤 p.129 第一劑第二劑第三劑追加 出生滿一年三個月隔二週出生滿二年三個月國小一年級 Clobetasone C 5 Unknown 1 Cloba cream 0.05%, 15g/tube <WCLOB02> Very high potency Rubella vaccine MMRII Japanese encephalitis vaccine (JE) Japanese encephalitis vaccine 0.1ml/dose <CBCG1> <C4IN1> <C5IN12 > <CMEASL1> <CMMR> 1ml/amp <CJAPANE> 0.1ml Children(2month~7yrs): /dose 1-3 yrs: 3yrs : 1ml Clobetasone C 5 Unknown 1 Cloba cream 0.05%, 5g/tube <WCLOB02> Very high potency 處方集內文勘誤 p.171 Darbepoetin alfa C 4 Unknown 1 NESP 20mcg/ml/vial <CDARBE1> 處方集內文勘誤 p.228 Levodopa and Benserazide C 4 Unsafe 1 Madopar 250, 1 tab Benserazide 50mg+Levodopa 200mg <KMADOP2> Madopar HBS, 1 tab Benserazide 25mg+Levodopa 100mg <KMADOP3> Darbepoetin alfa C 4 Unknown 1 NESP 20mcg/ml/syringe <CDARBE1> Levodopa and Benserazide C 4 Unsafe 1 Madopar 250, 1 tab Benserazide 50mg+Levodopa 200mg <KMADOP2> Madopar HBS, 1 cap Benserazide 25mg+Levodopa 100mg <KMADOP3> 處方集內文勘誤