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赛机蒲
7 years ago
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1 绎元元 , 3 3 doi: /wst R249 A 3 [1] 20%~29% [2 3] 10% 耀 25% [4 耀 6] [7] 1 Refractory Nephritic Syn 原 drome RNS <0.8 g kg -1 d [8] 元 KT 元元 952

2 2013 绎 Vol.15 No [9~11] 1.3 [12] % 25% 25% [12] [13] 耀 1 g kg -1 d ~0.8 g kg -1 d -1 逸 10 g d -1 臆 20 g L -1 1 耀 1.5 g kg -1 d 耀 35 kcal kg -1 d -1 5 耀 6 g d -1 2 耀 4 g d -1 [14 15] g d 耀 19 d 14 g d g d -1 [12 16] [17 18] 953

3 绎 [19 20] [21] [22] [23] [24] RAS 域 Angiotensin Converting Enzyme Inhibitors ACEI Angiotensin Receptor Blocker ARB [25] / 52% [26] 954

4 2013 绎 Vol.15 No / ACEI/ARB ACEI / ARB ACEI ARB RAS [25] AQP-2 mr 原 NA AVPR-V2 mrna [27 28] [29] g 30 g 25 g 15 g 15 g 6g 20 g 20 g 30 g 30 g 25 g 20 g 15 g 5g 3 伊伊垣 g/24 h 20.6 g L -1 HCV 垣 HCV 原 RNA 1.0 伊 10 6 IU ml ~6 / 3 垣 g/ 24 h ALB 14 g L -1 TC mmol L -1 TG 4.26 mmol L -1 LDL 原 C 9.14 mmol L -1 垣 4 II 5.1 ng ml -1 VI 81.1 ng ml ng ml ng ml -1 FSGS FS 原 GS g 30 g 25 g 15 g 15 g 15 g 25 g 50 g 20 g 15 g 15 g 15 g 5 g 1 3 耀 4 垣原 5 耀 7 g/24 h 20.6 g L g L -1 HCV 原 RNA 955

5 绎 <20 g L ,..,2012,24(5) 颐 483~ Troyanov S, Wall C A, Miller J A, et al. Idiopathic membranous nephropathy: definition and relevance of a partial remission. Kidney Int, 2004, 66(3) 颐 1199~ Troyanov S, Wall C A, Miller J A, et al. Focal and segmental glomerulosclerosis: definition and relevance of a partial remission. J Am Soc Nephrol, 2005, 16(4) 颐 1061~ Tse K C, Lam M F, Yip P S, et al. Idiopathic minimal change nephrotic syndrome in older adults: steroid responsiveness and pat 原 tern of relapses. NephrolDialTransplant, 2003, 18(7) 颐 1316~ Fujimoto S, Yamamoto Y, Hisanaga S, et al. Minimal change nephrotic syndrome in adults 颐 response to corticosteroid therapy and frequency of relapse. Am J Kidney Dis, 1991, 17(6) 颐 687~ Korbet S M, Schwartz M M, Lewis E J. Minimal -change glomeru 原 lopathy of adulthood. Am J Nephrol, 1988, 8(4) 颐 291~ Hull R P, Goldsmith D J. Nephrotic syndrome in adults. B M J, 2008, 336(76) 颐 1185~ Kaysen G A, Jones H J, Martin V, et al. A low -protein diet re 原 stricts albumin synthesis in nephrotic rats. J Clin Invest, 1989, 83 (5) 颐 1623~ Toporovski J, Carvalho N, Mello V R. Intestinal loss of albumin in children with nephrotic syndrome. Int J Pediatr Nephrol, 1982,3(1) 颐 5~7. 10 Schultze G, Ahuja S, Faber U, et al. Gastrointestinal protein loss in the nephrotic syndrome studied with 51Cr -albumin. Nephron, 1980, 25(5) 颐 227~ Jensen H, Jarnum S, Hart H J. Gastrointestinal protein loss and in 原 testinal function in the nephrotic syndrome. Nephron, 1966, 3(4) 颐 209~ Sharon A, Radko K, Brenner B M. Brenner and Rector's the Kid 原 ney. Philadelphia: Saunders Elsevier, 2007 颐 824 耀 Kaysen G A. Albumin metabolism in the nephrotic syndrome: the effect of dietary protein intake. Am J Kidney Dis, 1988, 12(6) 颐 461~ ,,.., 2004,18(12) 颐 564~ ,.., 2003,15(11) 颐 671~ Moshage H J, Janssen J A, Franssen J H, et al. Study of the molecular mechanism of decreased liver synthesis of albumin in in 原 flammation. J Clin Invest, 1987, 79(6) 颐 1635~ ,,,..,2008,19(4) 颐 874~ ,2010,32(4) 颐 172~ ,,,..,2006,28(1) 颐 61~ , 2008,2(3) 颐 ,,..,2010,28(6) 颐 433~ ,..,1995,5(3) 颐 31~32. 23,,,..,2003,23(10) 颐 757~ ,,,..,2008,33(8) 颐 965~967 25,.. :, ,,..,2010,399(8) 颐 1626~ ,,,. AQP- 2mRNA AVPR V2mRNA.,2009,32(6) 颐 926~ ,,,..,2009,3(14) 颐 59~60. 29,..,2008,6(12) 颐 843~

6 2013 绎 Vol.15 No.5 Discussion on Professor Huang Chunlin's TCM Medication Experiences for Patients with Hypoalbuminemia in Refractory Nephrotic Syndrome Zou Chuan, Liu Xusheng, Lu Fuhua, Huang Chunlin (Guangdong Provincial Hospital of Chinese Medicine, Guangzhou , China) Abstract: This paper summarized Professor Huang Chunlin's traditional Chinese medicine (TCM) medication expe 鄄 riences for patients with hypoalbuminemia in refractory nephrotic syndrome (RNS). This paper was divided into three parts. The first part was the overview of hypoalbuminemia in RNS. The second part was the TCM medica 鄄 tion experiences for patients with hypoalbuminemia in RNS which included the integrated application of tonifying the spleen, nourishing the liver and reinforcing the kidney. The third part was the explanation of the comprehen 鄄 sive application of Professor Huang Chunlin's TCM medication experiences for patients with hypoalbuminemia in RNS through the introduction of a typical case. TCM medication experiences for RNS treatment based on experi 鄄 ences of famous TCM doctors provided theoretical and practical basis for therapeutic regimen. Keywords: Refractory nephrotic syndrome, hypoalbuminemia, TCM medication experiences, Huang Chunlin 957

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