WADA simlar chemical structure or similar biological effect(s) include but not limited to ( ) (generic name) (5) 第五節 WADA 公告之運動禁藥清單 S1 S2 S4.4 S4.5 S6.a M1 M2 M3 一 賽內及賽外禁用物質及方法 ( ) S0. (non-approved substances) ( ) S1. (anabolic agents) 1. (anabolic androgenic steroids) a. 1-androstendiol methyldienolone 1-androstendione methyl-1-testosterone bolandiol methylnortestosterone bolasterone methyltestosterone boldenone metribolone (methyltrienolone) boldione mibolerone calusterone nandrolone clostebol 19-norandrostenedione danazol norboletone dehydrochloromethyltestosterone norclostebol desoxymethyltestosterone norethandrolone drostanolone oxabolone ethylestrenol oxandrolone fluoxymesterone oxymesterone formebolone oxymetholone furazabol prostanozol gestrinone quinbolone 4-hydroxytestosterone stanozolol mestanolone stenbolone mesterolone 1-testosterone metenolone tetrahydrogestrinone methandienone trenbolone methandriol methasterone b. androstenediol dihydrotestosterone androstenedione testosterone prasterone (dehydroepiandrosterone, DHEA) ( ) 5 -androstane-3α,17α-diol androst-5-ene-3α,17β-diol 5 -androstane-3α,17β-diol androst-5-ene-3β,17α-diol 5 -androstane-3β,17α-diol 7α-hydroxy-DHEA 5 -androstane-3β,17β-diol 7β-hydroxy-DHEA 3 -hydroxy-5α-androstan-17-one 7-keto-DHEA 3 -hydroxy-5α-androstan-17-one 19-norandrosterone androst-4-ene-3α,17α-diol 19-noretiocholanolone androst-4-ene-3α,17β-diol epi-dihydrotestosterone androst-4-ene-3β,17α-diol epitestosterone androst-5-ene-3α,17α-diol 32 33
4-androstenediol (androst-4-ene-3β,17β-diol) 5-androstenedione (androst-5-ene-3,17-dione) 2. (other anabolic agents) ( ) clenbuterol zeranol tibolone zilpaterol (selective androgen receptor modulators, SARMs) S2. (peptide hormones, growth factors S3. β 2 (beta-2 agonists) β 2 () salbutamol (24 1600 μg) formoterol (24 36 μg) salmeterol salbutamol 1000 ng/ml formoterol 30 ng/ml and related substances) 1. [erythropoiesis-stimulating agents erythropoietin (EPO) darbepoietin (depo) (hypoxiainducible factor (HIF) (methoxy polyethylene glycol-epoetin beta (CERA) peginesatide (hematide) 2. (chorionic gonadotrophin, CG) (luteinizing hormone, LH) 3. (insulins) 4. (corticotrophins) 5. (growth hormone, hgh) (insulin-like growth factors, IGF-1) (fibroblast growth factors, FGFs) (hepatocyte growth factor, HGF) (mechano growth factors, MGFs) (platelet-derived growth factor, PDGF) (vascular-endothelial growth factor, VEGF) S4. (hormone and metabolic modulators) 1. (aromatase inhibitors) ( ) aminoglutethimide, anastrozole, androsta-1,4,6-triene-3,17-dione (androstatrienedione), 4-androstene-3,6,17 trione (6-oxo), exemestane, formestane, letrozole, testolactone 2. (selective estrogen receptor modulators, SERMs) ( ) raloxifene, tamoxifen, toremifene 3. ( ) clomiphene, cyclofenil, fulvestrant 4. (agents modifying myostatin functions ) ( ) (m y o s t a t i n inhibitors) 5. (metabolic modulators) peroxisome proliferator activated receptor (PPAR ) agonists ( GW 1516) PPAR -AMPactivated protein kinase (AMPK) axis agonists ( AICAR) / 34 35
S5. (diuretics and other masking agents) ( ) haemoglobin ( ) desmopressin ( glycerol albumin, dextran, hydroxyethyl starch, mannitol) probenecid ( felypressin ) acetazolamide etacrynic acid amiloride furosemide bumetanide indapamide canrenone metolazone chlortalidone spironolactone thiazides ( :bendroflumethiazide, chlorothiazide, hydrochlorothiazide) triamterene (drospirenone pamabromdorzolamide brinzolamide ) ( formoterol, salbutamol, morphine, cathine, ephedrine, methylephedrine, pseudoephedrine) ( ) M1. (enhancement of oxygen transfer) 1. 2. ( ) perfluorochemicals, efaproxiral (RSR13) modified M2. (chemical and physical manipulation) 1. ( ) ( proteases) 2. 6 50 ml 3. M3. (gene doping) 1. 2. 二 僅賽內禁用之物質 S0~S5 M1~M3 S6. (stimulants) () imidazole 2012 a. adrafinil fenfluramine amfepramone fenproporex amiphenazole furfenorex amphetamine mefenorex amphetaminil mephentermine benfluorex mesocarb benzphetamine methamphetamine (d-) benzylpiperazine p-methylamphetamine bromantan methylenedioxyamphetamine 36 37
clobenzorex methylenedioxymethamphetamine cocaine cropropamide crotetamide dimethylamphetamine etilamphetamine famprofazone fencamine fenetylline modafinil norfenfluramine phendimetrazine phenmetrazine phentermine 4-phenylpiracetam (carphedon) prenylamine prolintane S7. (narcotics) buprenorphine dextromoramide diamorphine (heroin) fentanyl hydromorphone methadone morphine oxycodone oxymorphone pentazocine pethidine b. adrenaline cathine ephedrine etamivan etilefrine fenbutrazate fencamfamin heptaminol isometheptene levmetamphetamine meclofenoxate methylephedrine methylhexaneamine (dimethylpentylamine) methylphenidate nikethamide norfenefrine octopamine oxilofrine parahydroxyamphetamine pemoline pentetrazol phenpromethamine propylhexedrine pseudoephedrine selegiline sibutramine strychnine tuaminopheptane 2012 (bupropion, caffeine, nicotine, phenylephrine, phenylpropanolamine, pipradol, synephrine) S8. (cannabinoids) cannabis delta 9-tetrahydrocannabinol (THC) hashish cannabimimetics marijuana S9. (glucocorticosteroids) 三 特定運動項目禁用物質 P1. (alcohol) ( ) / 0.10 g/l (FAI) (WKF) (FITA, IPC) (FIM) (FIA) (UIF) () adrenaline cathine5 μg/ml ephedrine methylephedrine 10 µg/ml pseudoephedrine150 µg/ml P2. β (β-blockers) (FAI) 9 10 (FIQ) (FIA) (UIF) (WCBS) (ISSF, IPC) ( ) 38 39
(CMSB, IPC bowls) (FMB) (WDF) (IGF) (FITA, IPC) ( ) / (FIS) ( /U U / ) (Sports Council) β ( ) acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, celiprolol, esmolol, labetalol, levobunolol, metipranolol, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol 四 監控計畫物質 1. (stimulants) bupropion caffeine nicotine phenylephrine phenylpropanolamine pipradrol pseudoephedrine (< 150 μg/ml) synephrine 2. (narcotics) hydrocodone morphine/codeinetramadol 3. (glucocorticosteroids) 第六節運動禁藥的管制及教育 IOC (6) β 2 WA D A WADA 82 83 87 UCLA 5 12 (7) ( ) (8, 9) 40 41