: : : 19 :
1
206 1 2 3 4 2
30 70 98 295 5 Osteoclast Osteoblast 95 5 Na + Mg 2+ Fe 2+ F 30 70 98 2 95 Na + Mg 2+ Fe 2+ F Osteoporosis 0.5~1.0 3
65 65 25 Ca 2+ 3~5 Primary osteoporosis 1Postmenopausal osteoporosis 2Senile osteoporosis D Secondary osteoporosis 1 4
2 1 3 4 2 5 3 :Dilantin 1 3170 50~84 69 2 D 3 D 5
65 15 22 X X X X X X X 6
X 30 X BMD 1Quantitative Ultrasound, QUS 2 X Dual energy X-ray Absorptiometry, DXA X X X 30~50keV X 70keV X BMD 0.5 ~1.5 DXA DXA BMD BMD BMD BMD T-score WHO DXA 1.0 T-score 2.5 T-score1.0 T-score2.5 T-score2.5 7
/T- NTx DPD NTx DPD BMD 1 Bisphosphonates Calcitonin SERMs K Cathepsin K inhibitorsstrontium Ranelate 2 Parathyroid hormone Strontium Ranelate 8
Ω-3 D K 1000 2500 50 2 4 30 30 30 參 論 2500 130 10075 WHO 9
料 1995 1993 1996 2002 1997 Yvonne R. Sherrer, Robin K. Levinson 1996. A woman doctor s guide to Osteoporosis. New York Lowenstein Associates, Inc. 2007 The International Society for Clinical Densitometry, ISCD2013 1 21http://www.iscd.org/ National Osteoporosis Foundation 2013 1 21http://www.nof.org/ Beauty Nation 2013 2 2 http://www.beautynationpl.com/gbfh/osteoporosis.html 10