252 J Diag Pathol April 2014 Vol. 21 No. 4 X X 3A 4A 3B / < 2. 0 cm 4B 4C CD68 4D 3C 3D Giant cell tumour GCT of bone GCLSB giant cell lesion of

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1 251 doi: / j. issn WHO 2013 方三高 1, 肖华亮 1 2, 周晓军 WHO 肿瘤分类 WHO R 366 A IARC WHO WHO 2 11 vimitin S-100 ICD-O 1D ICD-O 0 ICD-O 1 t q24. 1 q21 ICD-O 3 2 subungual exostosis bizarre parosteal osteochondromatous proliferation BPOP 4 5 X Nora 6 1 osteochondromyxoma 3 Carney Carney 2B 2C X 2D 1A BPOP 3 osteoma / X 2A 1B 2002 WHO 1C WHO A X CT B C D S EnVision

2 252 J Diag Pathol April 2014 Vol. 21 No. 4 X X 3A 4A 3B / < 2. 0 cm 4B 4C CD68 4D 3C 3D Giant cell tumour GCT of bone GCLSB giant cell lesion of the small bones GCLSB WHO 1994 p benign notochordal cell tumours BNCT giant 2002 notochordal rest notochordal hamartoma GCLSB ecchordosis physaliphora spheno-occipitalis 7 8 EP 2002 BNCT Yamaguchi ~ < 30 2 A X B C D 3 A CT B C D 4 A B C D CD68 + EnVision

3 253 BNCT BNCT ACT 12 5A EP BNCT BNCT CB Ⅰ 5B 61% Ⅰ 14 Campanacci 5C % S-100 EMA CK 5D 6A atypical cartilaginous tumour ACT ACT 6B 6C Ki-67 6D ACT Ⅰ 5 A 4 B C D CK + EnVision 6 A B C D Ki-67 + EnVision 7 non-ossifying fibroma NOF NOF 7C storiform 7D benigh fibrous histocytoma BFH of bone BFH fibrous cortical defect FCD 16 7A NOF NOF 7B 30 ~ 60 BFH BFH NOF

4 254 J Diag Pathol April 2014 Vol. 21 No. 4 7 A X B C D 8 A B C CD31 + EnVision D CK + EnVision 8 epithelioid haemangioen classification of tumours. Pathology & genetics tumours of soft dothelioma EHE of bone tissue and bone M. Lyon IARC Press El Behery RA Bedrnicek J Lazenby A et al. Translocation t EHE q24. 1 q21 as the sole anomaly in a nasal 2002 WHO EHE chondromesenchymal hamartoma arising in a patient with EHE pleuropulmonary blastoma J. Pediatr Dev Pathol A 4 Thomas JG Henninger CA. Subungual exostosis J. Cutis James A Henderson S. Multiple recurrences of subungual exostosis in a child a unique presentation of a Nora s lesion J. 8B Foot Ankle Int Kuruvilla S Marco R Raymond AK et al. Bizarre parosteal osteochondromatous proliferation Nora s lesion with translocation t 1 17 q32 q21 a case report and role of cytogenetic studies on diagnosis J. Ann Clin Lab Sci Yanagisawa M Okada K Tajino T et al. A clinicopathological study of giant cell tumor of small bones J. Ups J Med Sci CD31 8C CD34 / FⅧRag CK 8D 8. M Yanagisawa M Kakizaki H Okada K et al. p63 as a prognostic 1 Fletcher CDM Bridge JA Hogendoorn P et al. WHO classification of tumours of soft tissue and bone M. Lyon IARC Press Fletcher CDM Unni KK Mertens F. World Health Organization marker for giant cell tumor of bone J. Ups J Med Sci Yamaguchi T Yamato M Saotome K. First histologically confirmed case of a classic chordoma arising in a precursor benign notochordal lesion differential diagnosis of benign and malignant

5 notochordal lesions J. Skeletal Radiol Yamaguchi T Suzuki S Ishiiwa H et al. Benign notochordal cell tumors a comparative histological study of benign notochordal cell tumors classic chordomas and notochordal vestiges of fetal intervertebral discs J. Am J Surg Pathol Nishiguchi T Mochizuki K Tsujio T et al. Lumbar vertebral chordoma arising from an intraosseous benign notochordal cell tumour radiological findings and histopathological description with a good clinical outcome J. Br J Radiol e Silvia T Sebastioan M Stefano B et al. Diagnosis and treatment of benign notochordal cell tumors of the spine report of cases and literature review J. Spine Phila Pa E Bj rnsson J McLeod RA Unni KK et al. Primary chondrosarcoma of long bones and limb girdles J. Cancer Campanacci DA Scoccianti G Franchi A et al. Surgical treatment of central grade 1 chondrosarcoma of the appendicular skeleton J. J Orthop Traumatol Bla M Palczewski P Swi tkowski J et al.cortical fibrous defects and non-ossifying fibromas in children and young adults the analysis of radiological features in 28 cases and a review of literature J. Pol J Radiol CK14 CK5 /6 p63 vimentin α-sma 1 Mammino JJ Vidmar DA. Syringocystadenoma papilliferum J. Int J Dermatol SCAP 2 Karg E Korom I Varga E et al. Congenital syringocystadenoma Mazoujian 6 SCAP papilliferum J. Pediatr Dermatol GCDFP-15 SCAP 3 Horenstein MG Prieto VG Burchette JL et al. Keratotic SCAP CEA melanocytic nevus a clinicopathologic and immunohistochemical Yamamoto 5 SCAP study J. J Cutan Pathol J Yamamoto O Doi Y Hamada T et al. An immunohistochemical and ultrastructural study of syringocystadenoma papilliferum J. Br J Dermatol Mazoujian G Margolis R. Immunohistochemistry of gross cystic disease fluid protein GCDFP-15 in 65 benign sweat gland SCAP tumors of the skin J. Am J Dermatopathol CEA GCDFP Jordan JA Brown OE Biavati MJ et al. Congenital SCAP syringocystadenoma papilliferum of the ear and neck treated with SCAP CO2 the CO 2 laser J. Int J Pediatr Otorhinolaryngol

陳建志陳登郎前言病例報告化膿性肉芽腫 (pyogenic granuloma, 或 granuloma pyogenicum) 是一種快速成長紅腫及有莖狀結節, 受傷時容易出血, 是一種相當常見的良性病變

陳建志陳登郎前言病例報告化膿性肉芽腫 (pyogenic granuloma, 或 granuloma pyogenicum) 是一種快速成長紅腫及有莖狀結節, 受傷時容易出血, 是一種相當常見的良性病變個案報告選擇適當的診斷 : 化膿性肉芽腫或小葉狀微血管瘤 1,2,3 4* 陳建志陳登郎行政院衛生署桃園醫院耳鼻喉科 1 ; 行政院衛生署竹東醫院耳鼻喉科 2 ; 天主教輔仁大學醫學院醫學系 3 4 ; 吉豐耳鼻喉科診所摘要化膿性肉芽腫