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1 8 1 Vol. 8 No Journal of Food Safety and Quality Jan., 2017 宋昀鹏 *, 李灏, 丁子元, 任涵玮, 徐扬 (, ) 摘要 :, 4,, 关键词 : ; ; Research advance of application of colloidal-gold strips readers in rapid detection SONG Yun-Peng *, LI Hao, DING Zi-Yuan, REN Han-Wei, Xu Yang (Tianjin Aquatic Technology Extending Stations, Tianjin , China) ABSTRACT: Due to the advantages of low cost, simple operation and high sensitivity, gold immunochromatography assay was widely used in the detection of microorganisms, heavy metals, mycotoxins and so on. As a combination of colloidal gold immunochromatography and modern automated detection technology, colloidal-gold strips readers had gained more attention by its characteristics, such as rapid detection and quantitative and intuitive reflection of the results. This paper introduced the construction of colloidal-gold strips readers, including signal acquisition module, signal processing module, communication module and additional module. The applications of colloidal-gold strips readers in the detection of agricultural and veterinary drugs, food additives, mycotoxins, microbial and comprehensive testing were also introduced. Furthermore, the potential applications of colloidal-gold strips readers in traceability system and the future development directions of intelligence and multi-function were analyzed, providing a reference for further study of colloidal-gold strips readers. KEY WORDS: colloidal-gold strips readers; rapid detection; quantitative analysis 1 引言,, [1] : [2] [3,4] [5,6] PCR [7,8] [9,10], [11] * 通讯作者 :,, @qq.com *Corresponding author: SONG Yun-Peng, Engineer, Tianjin Aquatic Technology Extending Stations, Tianjin , China @qq.com

2 164 8 (gold immunochromatography assay) 1990 Beggs ( : ), [12] ; (T ) (C ) ( ) ; T C,, [13], : (1), ; (2) ; (3) ; (4), 2 胶体金读数仪 [14] Chandler [15] Alexeter Technology 2007 BTA Test Strip Reader, Tetrance 3, 信号采集模块 1, 2 : 光敏电阻传感器和光纤传感器,, Suhyeon [16] LED( ),,, [17], [18], LED,,,,,, [19],,, [20],,,, 成像原理的图像传感器 CCD(charge coupled device) CMOS(complementary metal oxide semicoductor) [21,22] 2 [23] CMOS GC-MS, [24] TCS 3200( CMOS ), [25] CCD CMOS, 曣 [26] CCD A/D FIFO,, CCD,,,, 2.2 信号处理模块 2,,, Nios, ARM/ARM Cortex; ARM, [27], [28] 32 NiosⅡ [29]

3 1, : 165 ARM11, [14] STM32F40 (ARM Cortex-M7 ), [30] CCD -,, [31] C,,,,, [32] [33] PDE,, [34] k-means 2 曣 [26] CCD, [35] β,, (3) (y), (x, T C ), x T C ;, x T C (x, y), y, 2.3 人机交互模块, LED (organic light-emitting diode, OLED) (thin film transistor, TFT), [36-38] 2 [29] LCD, LCD,,, [39] LCD, [40], 2.4 附加模块, GPRS (RFID ) [41] ARM USB GPRS, GPRS, RFID, [42], ;, ;, [43] [23] -, CMOS RFID 3 胶体金读数仪的应用,

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