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1 5 3 Vol. 5 No Journal of Food Safety and Quality Mar., 2014 * 颜 腾 龙, 易 有 金 (, ) 摘 要 :,,,,, 关 键 词 : ; ; ; ; Progress of the lowering blood lipid effect of medicinal and edible medicine LONG Teng-Long, YI You-Jin * (College of Food Science and Technology, Hunan Agricultural University, Changsha , China) ABSTRACT: Medicinal and edible herbs can be used as a medicine or food for long-term. They have been widely applied in the pharmaceutical and food industries because of the effects of prevention and control of chronic diseases. This paper mainly describes 8 common Chinese medicinal and edible herbs (Hawthorn, Kudzu, Yiyiren, cassia, lily, yams, white beans, radish seed), and reviews their active ingredients and mechanism of action, to provide a certain reference for future research and development of medicinal and edible herbs. KEY WORDS: medicinal and edible medicine; lowing blood lipid; mechanism; active ingredients; progerss,,,,,,,,,,,,,,,, 1 高 血 脂 症 的 发 病 机 制 (hyperlipidemia, HLP), (TC) (TG) ( ),, (VLDL) (LDL) (HDL) VLDL,, VLDL, LDL * 通 讯 作 者 :,,, yiyoujin@163.com *Corresponding author: YI You-Jin, Professor, College of Food Science and Technology, Hunan Agricultural University, Changsha , China. yiyoujin@163.com

2 3, : 935, 44%, 12%, LDL HDL,,,,,,,,,,,,,,,,,,,,,,, 2 药 食 两 用 中 药 的 种 类, ,,,, 3 八 种 药 食 两 用 中 药 及 临 床 研 究 3.1 山 楂 30,,,, [1] 86,, 30d, 51, 30, 5, 94.1% [2], TC TG LDL,, 3.2 葛 根,, 12, ( ) 10, [3] 30, ; 90.0 ; , 16, 28, 6, 88% [4] 3.3 薏 苡 仁,,, Yun [5] 40, 4, [6] 100,, 32, 24, 8, 92% 3.4 决 明 子, [7] [8],, [9] 114

3 936 5,,, TC TG LDL-C, HDL-C [10] 64,, 39, 21, 4, 93.7% 3.5 百 合,,,,,, [11] ( ),,, 6, 3.6 山 药,,,,,,,,, [12] 10 ml/kg(2 /d),, HDL-C (HDL-C)/TC 3.7 白 扁 豆,,,,,,,, [13] ( ),,, 2, 3.8 莱 菔 子,,,,,,,,,,, [14] 38, 50%; 38%, 6 [15] 98,, 92% 4 八 种 药 食 两 用 中 药 降 血 脂 有 效 成 分 4.1 山 楂, [16], TG TC,,, [17], TC TG LDL-C, HDL-C, 4.2 葛 根,, 4 -OH -8-C-,, [18] [19], (50 mg/kg), TC TG LDL-C, HDL-C, (SOD), [20],, 4.3 薏 苡 仁

4 3, : 937 [21], SOD GSH-Px, CCl4, MDA, Yeh [22] SD, Yu [23], TC TG LDL-C, 4.4 决 明 子 1.2%,, Yen [24], [25], TC LDL-C TG,,,, TC TG LDL-C [26] 4.5 百 合 [27], TG TC LDL-C, HDL-C, [28],, 4.6 山 药, [29] 10 g/kg, ( TG) (TC) [30], GLU TC TG HDL-C, 4.7 白 扁 豆,,, [31], [32], SOD GSH-PX 4.8 莱 菔 子, [33], SOD, MDA, [34] ApoE,,, HDL-C 5 药 食 两 用 中 药 降 血 脂 作 用 机 制 5.1 对 胆 固 醇 吸 收 的 抑 制 作 用, [35],,,,, LDL,,,,, [36] [37],,,,, [38],,, 5.2 影 响 胆 固 醇 分 泌 和 合 成 [39]

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