2012 7 2 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 151 櫔櫔櫔櫔櫔櫔櫔櫔 1986 11 2 C 82 2 n = 42 n = 40 AP DF PNSW C AP DF PNSW AP 153. 40 ± 76. 99 μv AP 201. 80 ± 116. 66 μv P < 0. 05 DF 2. 90 ± 0. 30 cpm 2. 85 ± 0. 34 cpm DF 2. 68 ± 0. 56 cpm 2. 62 ± 0. 56 cpm P < 0. 05 DF 2. 93 ± 0. 31 cpm 2. 92 ± 0. 31 cpm DF 2. 58 ± 0. 57 cpm 2. 58 ± 0. 59 cpm P < 0. 05 PNSW 54. 25 ± 11. 95 % P < 0. 05 C 2. 50 ± 2. 02 pg /ml C 4. 24 ± 2. 38 pg /ml P < 0. 05 櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔 Electrogastrogram between diabetics with peripheral neuropathy and no peripheral neuropathy LI Juan * YANG Cai-zhe GUAN Xiao-hong. * The Postgraduate College of Anhui Medical University Hefei 230032 China Corresponding author GUAN Xiao-hong Email baojunli319@ yahoo. com. cn Abstract Objective To observe the characteristics of electrogastrogram EGG glycosylated hemoglobin and C-peptide in type 2 diabetics with peripheral neuropathy and no peripheral neuropathy analyze the relationship between diabetic peripheral neuropathy and diabetic gastric motility abnormalities. Methods Eighty-two diabetics were divided into normal electromyogram group NEMG n = 42 and abnormal electromyogram group AEMG n = 40 according to electromyogram test results. The average amplitude AP dominant frequency DF percentage of normal slow wave PNSW and other DOI 10. 3877 /cma. j. issn. 1673-9450. 2012. 07. 011 230032 100142 Email baojunli319@ yahoo. com. cn
152 2012 7 2 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 parameters of electrogastrogram were recorded. Fasting glucose postprandial glucose C-peptide glycosylated hemoglobin and glycosylated serum protein were also detected in the study. The parameters were analyzed to find out whether there were differences between the two groups. Results Compared with NEMG fasting and postprandial value of AP DF and PNSW in AEMG decreased. There were significant differences between the fasting AP 153. 40 ± 76. 99 μv and the postprandial AP 201. 80 ± 116. 66 μv P < 0. 05. The fasting DF in body of stomach and sinuses ventriculi of NEMG was 2. 90 ± 0. 30 cpm and 2. 85 ± 0. 34 cpm while the DF in body of stomach 2. 68 ± 0. 56 cpm and sinuses ventriculi 2. 62 ± 0. 56 cpm of AEMG greatly decreased P < 0. 05. The postprandial DF in body of stomach and sinuses ventriculi of NEMG was 2. 93 ± 0. 31 cpm and 2. 92 ± 0. 31 cpm while the postprandial DF in body of stomach 2. 58 ± 0. 57 cpm and sinuses ventriculi 2. 58 ± 0. 59 cpm of AEMG both decreased P < 0. 05. Compared with AEMG the fasting PNSW in body of stomach was significantly decreased P < 0. 05. Fasting and postprandial C-peptide both increased specifically postprandial C-peptide was lower with significant difference P < 0. 05. Conclusions Peripheral neuropathy implies large possibility of existence of abnormal gastric motility and delayed gastric emptying perhaps EGG can provide early diagnostic value in diabetic abnormal gastric motility. Key words Diabetic mellitus Diabetic neuropathies Gastric emptying Ectrogastrogram 4 2011 8 11 2 82 43 39 1 0. 9 1 27 ~ 75 57. 82 ± 12. 26 1 42 9. 87 ± 7. 27 42 18 24 2 55. 95 ± 13. 03 8. 36 ± 2 6. 38 40 25 15 59. 78 ± 11. 27 11. 44 ± 7. 88 1 n = 42 1999 WHO 1 7. 0 mmol /L/ 11. 1 mmol /L 2 7. 0 mmol /L/ 75 g OGTT 2 h 11. 1 mmol /L 1 < 18 > 75 2 3 1 x 珋 ± s P n = 40 55. 95 ± 13. 03 59. 78 ± 11. 27 0. 160 8. 36 ± 6. 38 11. 44 ± 7. 88 0. 057 mm Hg 131. 40 ± 17. 37 138. 20 ± 16. 85 0. 957 mm Hg 76. 69 ± 9. 07 74. 85 ± 10. 10 0. 386 mmol /L 2. 83 ± 0. 58 2. 65 ± 0. 91 0. 480 mmol /L 2. 16 ± 0. 85 1. 62 ± 1. 15 0. 120 mmol /L 1. 10 ± 0. 24 1. 08 ± 0. 30 0. 778 mmol /L 2. 83 ± 0. 58 2. 65 ± 0. 91 0. 293 24 h μg/min 23. 65 ± 36. 29 144. 10 ± 419. 17 0. 078 1 mm Hg = 0. 133 kpa
2012 7 2 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 153 3. percentage of normal slow 1. 2 h wave PNSW Prodia Dianostics 65% 2 h 65% HA-8160 GSP Siemens healthcare Dianotics ADVIA CENTAUR C SPSS 17. 0 2 h C AP DF PNSW 2. ± x 珋 ± s XDJ-S8B t AP DF 8 PNSW % min 1 12 h χ 2 P < 0. 05 3 d 8 ~ 11 5 ~ C 10 min 95% P < 0. 05 2 P > 0. 05 C 3 ~ 5 cm C 1 cm 2 ~ P < 0. 05 4 cm 1 /2 1 /2 2 P > 0. 05 AP 3 8 min AF 100 g 50 g 1 495 kcal P < 0. 05 63% 25% AF 12% 5 ~ 10 min 3 5 min 8 min DF 1. average amplitude AP DF P < 0. 05 3 150 ~ 250 μv 150 ~ 350 μv PNSW 2. dominant frequency DF PNSW PNSW 2. 4 ~ 3. 6 cpm P < 0. 05 3 2 C x 珋 ± s mmol /L C- pg /ml % μmol /L 42 7. 91 ± 2. 84 11. 10 ± 3. 72 a 1. 72 ± 1. 06 4. 24 ± 2. 38 b 8. 82 ± 1. 98 342. 86 ± 120. 94 40 8. 22 ± 1. 96 12. 40 ± 3. 45 c 1. 36 ± 1. 39 2. 50 ± 2. 02 d 9. 28 ± 2. 35 343. 55 ± 124. 88 P 0. 565 0. 107 0. 192 0. 001 0. 348 0. 980 a P = 0. 00 b P = 0. 000 c P = 0. 00 d P = 0. 004
154 2012 7 2 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 AP AP AP P > 0. 05 C DF C B P < 0. 05 C PNSW PNSW C C B P > 0. 05 4 Takahashi 4 10 mmol /L 15 min 50% 50% ~ 76% 2 Ali 3 29% 5 Intagliata Koch 6 3 μv 42 x 珋 ± s cpm % 184. 50 ± 82. 21 185. 00 ± 105. 14 2. 90 ± 0. 30 2. 85 ± 0. 34 60. 77 ± 9. 09 55. 23 ± 12. 06 215. 12 ± 85. 56 206. 14 ± 71. 71 2. 93 ± 0. 31 2. 92 ± 0. 31 62. 03 ± 8. 34 60. 50 ± 8. 3 40 163. 18 ± 83. 01 a 153. 40 ± 76. 99 b 2. 68 ± 0. 56 c 2. 62 ± 0. 56 d 54. 25 ± 11. 95 e 54. 27 ± 13. 47 f 204. 18 ± 96. 58 g 201. 80 ± 116. 66 h 2. 58 ± 0. 57 i 2. 58 ± 0. 59 j 57. 58 ± 17. 20 k 58. 36 ± 16. 39 l P 1 0. 098 0. 285 0. 671 0. 318 0. 510 0. 230 P 2 0. 045 0. 023 0. 442 0. 742 0. 318 0. 227 P 1 AF P 2 AF a P = 0. 246 b P = 0. 733 c P = 0. 022 d P = 0. 029 e P = 0. 007 f P = 0. 733 g P = 0. 588 h P = 0. 456 i P = 0. 001 j P = 0. 001 k P = 0. 137 l P = 0. 456 4 % AP DF 42 PNSW 25 59. 5% 11 26. 2% 38 91. 5% 36 85. 7% 12 28. 6% 6 14. 3% 15 35. 7% 23 54. 8% 38 91. 5% 41 97. 6% 17 40. 5% 13 31. 0% 40 27 67. 5% a 12 30. 0% b 26 65. 0% c 23 57. 5% d 5 12. 5% e 6 15. 0% f 21 52. 5% g 21 52. 5% h 26 65. 0% i 29 70. 5% j 14 35. 0% k 14 35. 0% l a P = 0. 45 b P = 0. 70 c P = 0. 01 d P = 0. 00 e P = 0. 07 f P = 0. 93 g P = 0. 13 h P = 0. 84 i P = 0. 01 j P = 0. 00 k P = 0. 61 l P = 0. 70
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