Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 parameters of electrogastrogram were recorded. Fasting g

Size: px

Start display at page:

Download "Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 parameters of electrogastrogram were recorded. Fasting g"

切怡舒
9 years ago
Views:

1 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No 櫔櫔櫔櫔櫔櫔櫔櫔 C 82 2 n = 42 n = 40 AP DF PNSW C AP DF PNSW AP ± μv AP ± μv P < DF ± cpm ± cpm DF ± cpm ± cpm P < DF ± cpm ± cpm DF ± cpm ± cpm P < PNSW ± % P < C ± pg /ml C ± pg /ml P < 櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔櫔 Electrogastrogram between diabetics with peripheral neuropathy and no peripheral neuropathy LI Juan * YANG Cai-zhe GUAN Xiao-hong. * The Postgraduate College of Anhui Medical University Hefei China Corresponding author GUAN Xiao-hong baojunli319@ yahoo. com. cn Abstract Objective To observe the characteristics of electrogastrogram EGG glycosylated hemoglobin and C-peptide in type 2 diabetics with peripheral neuropathy and no peripheral neuropathy analyze the relationship between diabetic peripheral neuropathy and diabetic gastric motility abnormalities. Methods Eighty-two diabetics were divided into normal electromyogram group NEMG n = 42 and abnormal electromyogram group AEMG n = 40 according to electromyogram test results. The average amplitude AP dominant frequency DF percentage of normal slow wave PNSW and other DOI /cma. j. issn baojunli319@ yahoo. com. cn

2 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 parameters of electrogastrogram were recorded. Fasting glucose postprandial glucose C-peptide glycosylated hemoglobin and glycosylated serum protein were also detected in the study. The parameters were analyzed to find out whether there were differences between the two groups. Results Compared with NEMG fasting and postprandial value of AP DF and PNSW in AEMG decreased. There were significant differences between the fasting AP ± μv and the postprandial AP ± μv P < The fasting DF in body of stomach and sinuses ventriculi of NEMG was ± cpm and ± cpm while the DF in body of stomach ± cpm and sinuses ventriculi ± cpm of AEMG greatly decreased P < The postprandial DF in body of stomach and sinuses ventriculi of NEMG was ± cpm and ± cpm while the postprandial DF in body of stomach ± cpm and sinuses ventriculi ± cpm of AEMG both decreased P < Compared with AEMG the fasting PNSW in body of stomach was significantly decreased P < Fasting and postprandial C-peptide both increased specifically postprandial C-peptide was lower with significant difference P < Conclusions Peripheral neuropathy implies large possibility of existence of abnormal gastric motility and delayed gastric emptying perhaps EGG can provide early diagnostic value in diabetic abnormal gastric motility. Key words Diabetic mellitus Diabetic neuropathies Gastric emptying Ectrogastrogram ~ ± ± ± ± ± ± n = WHO mmol /L/ mmol /L mmol /L/ 75 g OGTT 2 h mmol /L 1 < 18 > x 珋 ± s P n = ± ± ± ± mm Hg ± ± mm Hg ± ± mmol /L ± ± mmol /L ± ± mmol /L ± ± mmol /L ± ± h μg/min ± ± mm Hg = kpa

3 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No percentage of normal slow 1. 2 h wave PNSW Prodia Dianostics 65% 2 h 65% HA-8160 GSP Siemens healthcare Dianotics ADVIA CENTAUR C SPSS h C AP DF PNSW 2. ± x 珋 ± s XDJ-S8B t AP DF 8 PNSW % min 1 12 h χ 2 P < d 8 ~ 11 5 ~ C 10 min 95% P < P > C 3 ~ 5 cm C 1 cm 2 ~ P < cm 1 /2 1 /2 2 P > AP 3 8 min AF 100 g 50 g kcal P < % 25% AF 12% 5 ~ 10 min 3 5 min 8 min DF 1. average amplitude AP DF P < ~ 250 μv 150 ~ 350 μv PNSW 2. dominant frequency DF PNSW PNSW 2. 4 ~ 3. 6 cpm P < C x 珋 ± s mmol /L C- pg /ml % μmol /L ± ± a ± ± b ± ± ± ± c ± ± d ± ± P a P = b P = c P = d P =

4 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No. 2 AP AP AP P > C DF C B P < C PNSW PNSW C C B P > Takahashi 4 10 mmol /L 15 min 50% 50% ~ 76% 2 Ali 3 29% 5 Intagliata Koch 6 3 μv 42 x 珋 ± s cpm % ± ± ± ± ± ± ± ± ± ± ± ± ± a ± b ± c ± d ± e ± f ± g ± h ± i ± j ± k ± l P P P 1 AF P 2 AF a P = b P = c P = d P = e P = f P = g P = h P = i P = j P = k P = l P = % AP DF 42 PNSW % % % % % % % % % % % % % a % b % c % d % e % f % g % h % i % j % k % l a P = b P = c P = d P = e P = f P = g P = h P = i P = j P = k P = l P = 0. 70

5 Chin J Injury Repair and Wound Healing Electronic Edition April 2012 Vol 7 No AP DF 65% AP DF DF DPN 4 2 AP AP DF DF 4 2 DF DF < cpm 1 /3 3 /min 1 Asakawa H Onishi M Hayashi I et al. Comparison between coefficient of R-R interval variation and gastric emptying in type 2 DF < 2. 4 cpm diabetes meilitus patients J. J Gastroenterol Hepatol M Cajal 3 Ali T Hasan M Hamadani M et al. Gastroparesis J. South Med J interstitial cells of Cajal ICC Forster 8 4 Takahashi T Matsuda K Kono T et al. lnhibitory effects of hyperglycemia on neural activity of the vagus in rats J. Intensive ICC Care Med Rayner CK Verhagen MA Hebbard GS et al. Proximal gastric compliance and perception of distension in type I diabetes mellitus ICC effects of hyperglycemia J. Am J Gastrocnterol Forster 6 Intagliata N Koch KL. Gastroparesis in type 2 diabetes mellitus ICC prevalence etiology diagnosis and treatment J. Curr Gastroenterol Rep J ICC 8 Forster J Damjanov I Lin Z et al. Absence of the interstitial cells of Cajal in patients with gastroparesis and correlation with clinical findings J. J Gastrointest Surg PNSW J /CD

600 现代药物与临床 Drugs & Clinic 第 31 卷第 5 期 2016 年 5 月 were significantly decreased, but the levels of IL-12 in two groups were significantly increa

600 现代药物与临床 Drugs & Clinic 第 31 卷第 5 期 2016 年 5 月 were significantly decreased, but the levels of IL-12 in two groups were significantly increa 现代药物与临床 Drugs & Clinic 第 31 卷第 5 期 2016 年 5 月 599 喘可治注射液联合细辛脑注射液治疗小儿毛细支气管炎的临床研究唐辉英, 佘定平, 马颐娇深圳市儿童医院呼吸科, 广东深圳 518026 摘要 : 目的探讨喘可治注射液联合