Doctoral Program Graduate School of Medical and Dental Sciences Syllabus 2014 Tokyo Medical and Dental University

Transcription

1 Doctoral Program Graduate School of Medical and Dental Sciences Syllabus 2014 Tokyo Medical and Dental University

2 Doctoral Program:Medical and Dental Sciences Index Subject Page 初期研究研修 Initial Research Training 1 医歯学総合特論 ( 大学院セミナー ) Special of Global Medical and Dental Study - 医歯学先端研究特論 ( 大学院特別講義 ) Special of Advanced Medical and Dental Study - 医歯学総合研究科コース特論 Basic-Clinical Borderless Education 3 包括臨床演習 Comprehensive dental clinical practice - 先端口腔科学特論 Frontier Oral and Maxillofacial Health Sciences - < 1 >

3 Division No. Department Page 口腔機能再構築学 Oral Health Sciences 顎顔面頸部機能再建学 Maxillofacial and Neck Reconstruction 生体支持組織学 Bio-Matrix 1 口腔病理学 Oral Pathology - 2 細菌感染制御学 Bacterial Pathogenesis 5 3 分子免疫学 Molecular Immunology 6 4 先端材料評価学 Advanced Biomaterials 7 5 口腔病態診断科学 Diagnostic Oral Pathology - 6 有機材料学 Organic Biomaterials 8 7 機能材料学 Functional Material 9 8 口腔放射線腫瘍学 Oral Radiation Oncology 10 9 顎口腔外科学 Oral and Maxillofacial Surgery 口腔放射線医学 Oral and Maxillofacial Radiology 麻酔 生体管理学 Anesthesiology and Clinical Physiology 疼痛制御学 Orofacial Pain Management 小児歯科学 Pediatric Dentistry 咬合機能矯正学 Orthodontic Science う蝕制御学 Cariology and Operative Dentistry 摂食機能保存学 Fixed Prosthodontics 歯髄生物学 Pulp Biology and Endodontics 部分床義歯補綴学 Removable Partial Prosthodontics インプラント 口腔再生医学 Oral Implantology and Regenerative Dental Medicine 形成 再建外科学 Plastic and Reconstructive Surgery 頭頸部外科学 Head and Neck Surgery 腫瘍放射線治療学 Radiation Therapeutics and Oncology 顎顔面解剖学 Maxillofacial Anatomy 認知神経生物学 Cognitive Neurobiology 分子発生学 Molecular Craniofacial Embryology 分子細胞機能学 Cellular Physiological Chemistry 金属材料学 Metals バイオデザイン Biodesign 顎顔面外科学 Maxillofacial Surgery 顎顔面矯正学 Maxillofacial Orthognathics 顎顔面補綴学 Maxillofacial Prosthetics 細胞生物学 Cell Biology 病態代謝解析学 Medical Biochemistry 運動器外科学 Joint Surgery and Sports Medicine 硬組織構造生物学 Biostructural Science 硬組織薬理学 Pharmacology 結合組織再生学 Connective Tissue Regeneration 硬組織病態生化学 Biochemistry 分子情報伝達学 Cell Signaling 無機材料学 Inorganic Materials 歯周病学 Periodontology 53 < 2 >

4 Division No. Department Page 環境社会医歯学 Public Health 老化制御学 Gerontology and Gerodontology 全人的医療開発学 Comprehensive Patient Care 認知行動医学 Cognitive and Behavioral Medicine 42 健康推進医学 Health Promotion 国際環境寄生虫病学 Environmental Parasitology 法医学 Forensic Medicine 国際保健医療協力学 International Health and Medicine 政策科学 Health Care Management and Planning 分子疫学 Molecular Epidemiology 研究開発学 Research Development 医療政策情報学 Health Policy and Informatics 先進倫理医科学 Life Sciences and Bioethics 法歯学 Forensic Dentistry 医療経済学 Health Care Economics 歯学教育開発学 Dental Education Development 健康推進歯学 Oral Health Promotion スポーツ医歯学 Sports Medicine and Dentistry 歯学教育システム評価学 Educational System in Dentistry 教育メディア開発学 Educational Media Development 保険医療管理学 Insured Medical Care Management 血流制御内科学 Geriatrics and Vascular Medicine リハビリテーション医学 Rehabilitation Medicine 高齢者歯科学 Gerodontology and Oral Rehabilitation 臨床検査医学 oratory Medicine 救命救急医学 Critical Care Medicine 心療 緩和医療学 Liaison Psychiatry and Palliative Medicine 薬物動態学 Pharmacokinetics and Pharmacodynamics 臨床医学教育開発学 Medical Education Research and Development 救急災害医学 Acute Critical Care and Disaster Medicine 臨床腫瘍学 Clinical Oncology 障害者歯科学 Dentistry for Persons with Disabilities 総合診療歯科学 General Dentistry 歯科心身医学 Psychosomatic Dentistry 歯科医療行動科学 Behavioral Dentistry 顎関節口腔機能学 Temporomandibular Joint and Oral Function 先駆的医療人材育成 Professional Development in Health Sciences 神経機能形態学 Neuroanatomy and Cellular Neurobiology システム神経生理学 Systems Neurophysiology 細胞薬理学 Pharmacology and Neurobiology 分子神経科学 Molecular Neuroscience 神経病理学 Neuropathology 眼科学 Ophthalmology and Visual Science 耳鼻咽喉科学 Otorhinolaryngology 脳神経病態学 Neurology and Neurological Science 精神行動医科学 Psychiatry and Behavioral Sciences 106 < 3 >

5 Division No. Department Page 認知行動医学 Cognitive and Behavioral Medicine 生体環境応答学 Bio-Environmental Response 器官システム制御学 Systemic Organ Regulation 先端医療開発学 Advanced Therapeutic Sciences 84 脳神経機能外科学 Neurosurgery 血管内治療学 Endovascular Surgery NCNP 脳機能病態学 NCNP Brain Physiology and Pathology 免疫アレルギー学 Immune Regulation ウイルス制御学 Molecular Virology 免疫治療学 Immunotherapeutics 環境生物学 Cellular and Environmental Biology 生体防御学 Biodefense Research 病態細胞生物学 Pathological Cell Biology 代謝応答化学 Pathological Biochemistry 免疫応答制御学 Immunology 発生発達病態学 Pediatrics and Developmental Biology 膠原病 リウマチ内科学 Rheumatology 皮膚科学 Dermatology NCCHD 成育医学 NCCHD Child Health and Development 人体病理学 Human Pathology 細胞生理学 Physiology and Cell Biology 分子細胞循環器学 Molecular Cellular Cardiology 分子代謝医学 Molecular Medicine and Metabolism 幹細胞制御 Stem Cell Regulation 分子薬理学 Molecular Pharmacology 細胞機能調節学 Molecular Cell Biology 統合エピゲノミクス Epigenetics 時間生物学 Chronobiology 幹細胞医学 Stem Cell Biology 統合呼吸器病学 Respiratory Medicine 消化器病態学 Gastroenterology and Hepatology 腫瘍外科学 Surgical Oncology 循環制御内科学 Cardiovascular Medicine 心肺統御麻酔学 Anesthesiology 心臓血管外科学 Cardiovascular Surgery 腎臓内科学 Nephrology 生殖機能協関学 Comprehensive Reproductive Medicine 腎泌尿器外科学 Urology 食道 一般外科学 Esophageal and General Surgery 呼吸器外科学 Thoracic Surgery 都医学研疾患分子生物学 Igakuken Disease-oriented Molecular Biology 臨床解剖学 Clinical Anatomy システム発生 再生医学 Systems BioMedicine 包括病理学 Comprehensive Pathology 分子腫瘍医学 Molecular Oncology 診断病理学 Surgical Pathology 156 < 4 >

6 Division No. Department Page 先端医療開発学 Advanced Therapeutic Sciences 126 疾患モデル動物解析学 Experimental Animal Model for Human Disease シグナル遺伝子制御学 Signal Gene Regulation 生体機能分子科学 Biofunctional Molecular Science 医薬品化学 Medicinal Chemistry 先端計測開発医学 Biomedical Devices and Instrumentation 先端機器開発医学 Medical Instrument バイオメカニクス Biomechanics 生体界面工学 Biointerface Engineering 生体材料機能医学 Material Biofunctions 遺伝制御学 Genetic Regulation 生命情報学 Bioinformatics 遺伝子応用医学 Applied Gene Medicine 分子細胞遺伝学 Molecular Cytogenetics 遺伝生化学 Biochemical Genetics 構造生物学 Structural Biology 血液内科学 Hematology 分子内分泌代謝学 Molecular Endocrinology and Metabolism 肝胆膵 総合外科学 Hepatobiliary and Pancreatic Surgery 整形外科学 Orthopaedic and Spinal Surgery 画像診断 核医学 Diagnostic Radiology and Nuclear Medicine 疾患ゲノミクス Disease Genomics 疾患多様性遺伝学 Human Genetics and Disease Diversity 応用再生医学 Applied Regenerative Medicine JFCR 腫瘍制御学 JFCR Cancer Biology 180 < 5 >

7 Initial Research Training (for international students) (Code: st year 1unit) [Course Description] Research work should be done in accordance with various rules and regulations including those related to ethics, and those related to handling of toxic substances, radioactive materials and animals. This series of lectures introduce rules and regulations that the students should follow during research work. Also, the students learn how to use libraries and data bases, and how to avoid scientific misconducts. [Grading] Attendance [Course Schedule] See the next page; Table [Notes] If you register Initial Research Training, you must choose one for Japanese (Code: 3002) or for international students (Code: 3102). If you are the Japanese or the international students who are fluent speakers of Japanese, you should be advised to take part in Initial Research Training for Japanese (Code: 3002). [Inquiring] Educational Affair Section TEL ,

8 Initial Research Training FY2014 Graduate School of Medical and Dental Sciences Date:Mon. 21nd April to Fri. 26th April 2014 Venue: Room 3, 11th floor, M&D Tower (Excluding lectures with an asterisk * ) Opening Remarks:Dean, Graduate School of Medical and Dental Sciences at 14:30 21nd April Timetable: date First ( 14:40~ 15:40) Second ( 15:50~ 16:50) Third ( 17:00~ 18:00) Ethics of Researcher Thesis Writing and Presenting Research Methods for studying the development 21-Apr Sachiko ISEKI Hajime KARASUYAMA Hiroshi NISHINA Mon. Molecular Craniofacial Embryology Lmmune Regulation Developmental and Regenerative Biology Professor Professor Professor Introduction to Bioinformatics To conduct a safe and fair research How to make scientific researches reliable and successful 22-Apr Masaki MORIOKA Hirobumi TERAOKA Tetsuya TAGA Tue. Bioinformatics Office for Research Safety and Management Stem Cell Regulation Assistant Professor Professor emeritus Professor Instrumental analysis for life science Use and Handling of Radioisotopes and Radiations Study of Functional gene and genome 23-Apr Takeshi KASAMA Masayuki HARA Masataka NAKAMURA Wed. Instrumental Analysis Research Division General Isotope Research Division Human Gene Sciences Research Division Associate Professor Associate Professor Professor The Design of Animal Experiments Immunology in Medical Research Biosafety and basic microbiological techniques 24-Apr Masami KANAI Mari KANNAGI Shoji YAMAOKA Thu. Center for Experimental Animal Immunotherapeutics Molecular Virology * Professor Professor Professor Bioethics * Collaborative Institutional Training Initiative JAPAN program * Literature search Utilization of library 25-Apr Masayuki YOSHIDA Masayuki YOSHIDA Atsuhiro KINOSHITA Fri. Life Science and Bioethics Research Center Life Science and Bioethics Research Center Institute for Library and Media Information Technology Professor Professor Professor -2-

9 Basic-Clinical Borderless Education (Code: 8603, 1 st ~2 nd year: 6units) Contact person: Ikuo Morita morita.cell@tmd.ac.jp 2 Description and Timetable This course consists of "course lectures" and "research progress meeting". At the end of the course, understanding and exploring the interrelation between the basic and clinical research is achieved. Course s Outline: Students who take this course will select one of following five lecture series. Oral Biochemistry, Mucosal Biology and Diseases Oral Health and Education Developmental Biology and Reconstruction Biomaterials and Bioengineering Series in English Each lecture series comprises 9 field specific lectures and 6 common lectures. series in English is composed of three lectures held in English from each research field (total 12 lectures) and 3 common lectures in which the slides are presented in English. コース別授業 s ニ re c tu ハ le X [ cific e R s p ld F ie Field specific lectures 口腔化学 機能コース Oral Biochemistry, Mucosal Biology, and Diseases 日本語 (6コマ) in Japanese(6lectures) 英語 (3コマ) in English(3lectures) s ニ re c tu ハ le n 生命倫理関連授業 Bioethics o m m o C 論文作成に関連した必要知識 Knowledge required to 共通授業 Common s 健康科学コース Oral Health and Education 日本語 (6コマ) in Japanese(6lectures) 英語 (3コマ) in English(3lectures) + + 発生 再構築学コース Developmental Biology and Reconstruction 日本語 (6コマ) in Japanese(6lectures) 英語 (3コマ) in English(3lectures) 知財関連授業 Intellectual Property 日本語 (2 コマ ) in Japanese(2classes) 生命倫理関連授業 Bioethics 日本語 (1コマ) in Japanese(1class) 英語スライド (1コマ) by English slide(1lecture) 論文作成に関連した必要知識 Knowledge required to create a paper 英語スライド (2 コマ ) by English slide(2lectures) 組織材料工学コース Biomaterials and Bioengineering 日本語 (6コマ) in Japanese(6lectures) 英語 (3コマ) in English(3lectures) *s appeared in white letters on the black background are designated Series in English. Each lecture series provides current topics in the research field with the interest in the methods, basic study and the possibility of clinical application. Common lectures are set up for understanding the bioethics, intellectual properties and the basics knowledge required for conducting the research. For the detail of the lectures including the schedule, venues, please check the website and bulletin board. Research progress meeting Outline: Our program adopted a Three supervisor system. For each student, the main supervisor and two sub-supervisors are selected from both basic and clinical teaching staffs. The three supervisor system works to improve research plans and directions of the student by holding regular discussions, and supports students to write papers (thesis). -3-

10 By the middle of 2nd year grade three supervisors are selected according to the research theme of each student. A notice of research progress meeting is issued by Dept. of educational affairs twice a year and students arrange their meeting with their supervisors. After the meeting, a report with the fixed form is submitted to Dept. of educational affairs. The submission deadline is the end of June and December. The submission of the report is required for credit earning, and the data is used to verify the research progress and focus on problems. Note: In case of postponement of the research progress meeting, consult with the main-supervisor and inform Dep. of educational affairs. Change of the supervisor shall be discussed with the professor of affiliated section and informed to Dept. of educational affairs. Research progress meeting is carried out until completion of writing the manuscript. 3.Course Format: Course s and group discussion (research progress meeting) For venues and other detailed information, please check the website and bulletin board. For the research progress meeting, the students arrange the venue by themselves. Evaluation will be given according to the participation in the lecture series and report submission of the research progress meeting. The research progress meeting report needs to be submitted more than once by the end of 2nd year,. Course outline is introduced at the first lecture of each lecture series, therefore registered students are asked to attend it. 6.Notes: For detailed information, please check the website and bulletin board. URL -4-

11 Bacterial Pathogenesis (Code: 1 st -year : 6 units) (Code: 1 st -~2 nd -year: 4 units) (Code: 2 nd -~3 rd -year: 8 units) Not offered -5-

12 Molecular Immunology (Code:8031,1 st -year : 6 units) (Code:8032,1 st -~2 nd -year: 4 units) (Code:8033,2 nd -~3 rd -year: 8 units) Professor Miyuki AZUMA, Associate Professor Shigenori NAGAI, Assistant Professor Tatsukuni OHNO Contact person: Department of Molecular Immunology Miyuki AZUMA miyuki.mim@tmd.ac.jp Main objective of Molecular Immunology in the graduate course is to understand and to learn how the systemic and organ-specific immune systems works in health and diseases. Students also learn the strategies how to regulate immune diseases. Every Monday from May 12 to July 7, 17:00-19:00 Special A/N (during the above lecture period) Seminar A/N Journal Club Odd Week Saturday 15:30-17:30 Conference A/N To understand and discuss the basic and up-date immunological research by reading review and current topic articles and to make research plans Journal Club Odd Week Saturday 15:30-17:30 To obtain fundamental techniques for immunological research A/N Presentation by a small group and comprehensive discussion M&D tower, 6F Seminar room 11 Comprehensive assessment 6.Notes: s have been made in English (It depends on participants) -6-

13 Advanced Biomaterials (Code:8041,1 st -year : 6 units) (Code:8042,1 st -~2 nd -year: 4 units) (Code:8043,2 nd -~3 rd -year: 8 units) Professor: Motohiro UO, Associate Professor: Toshio HONGO, Assistant Professor: Takahiro WADA Part-time senior lecturer: Atsunobu Masuno Contact person: Motohiro UO uo.abm@tmd.ac.jp Upon successful completion of the course, the student will be able to: 1. Describe the basic classification of dental materials 2. Understand basic characteristics of recent dental materials 3. Explain current scientific theory regarding evaluating mechanical properties 4. Discuss characteristics of recent representative oral biomaterials and equipment. Thursday morning, 10 am - 12 am (May and June) Special As needed (normally, 4 times per one year) Seminar 1st and 3rd Monday afternoon (2 pm - 3 pm) Journal Club Every Monday afternoon (1pm - 2 pm) Conference of the department of restorative sciences will be held four times in year Students will be able to explain their research results using PowerPoint. Students will be able to display their research results as a poster presentation. Student will be able to discuss their findings with other students. As needed Students should measure basic mechanical properties using testing machine. Students should determine several hardness values of dental materials. Student should analyze crystalline component using X-ray diffractometer Student should analyze atomic vibration using Fourier-transfer-infrared-scopy. Participation in a research group As needed All coerces are basically few people education system for providing free discussion. Please contact the faculty adviser before attending class. Comprehensive assessment based on participation and activity for lecture, practice and lab studies. 6.Notes: -7-

14 Organic Biomaterials (Code:8061,1 st -year : 6 units) (Code:8062,1 st -~2 nd -year: 4 units) (Code:8063,2 nd -~3 rd -year: 8 units) Professor Nobuhiko YUI, Assistant Professor Ji-Hun SEO, and Assistant Professor Atsushi TAMURA Contact person: Nobuhiko YUI yui.org@tmd.ac.jp The progress in nano-biotechnology controlling the organization of nano-scaled assemblies in molecular levels is indispensable to the development of novel biomaterials for the next generation. In this lecture, basic concept of polymeric biomaterials will be introduced for understanding the medical applications of nano-materials. Also, recent topics on advanced medicines including drug delivery systems and regenerative medicine will be discussed. as needed Special as needed Seminar as needed Journal Club as needed Conference as needed To research recent studies on biomaterials for learning more about advanced investigation and training logical thinking for the research works. Every Wednesday from 16:00 to 18:00 (Nov. 12 th Dec. 17 th, 2014) To evaluate the functionalities of a variety of biomaterials designed in the laboratory in terms of their final goals in the fields of drug delivery and regenerative medicine. For example, to characterize nano-biomaterials, investigate the properties in drug delivery performance, and evaluate the cellular interaction with these biomaterials. As needed To do either in a didactic manner or in reading references in turns, and to give any opportunity for mutual discussions. To be announced. To evaluate both the attendance (the lecture, practice and lab.) and the score of the reports submitted. 6.Notes: none -8-

15 Functional Material (Code:8071,1 st -year : 6 units) (Code:8072,1 st -~2 nd -year: 4 units) (Code:8073,2 nd -~3 rd -year: 8 units) 1. Instructors: Tsuyoshi Kimura Kwangwoo Nam Contact person: Tsuyoshi Kimura kimurat.mbme@tmd.ac.jp The objective is to understand the materials, especially polymeric materials, for medical use. In the lecture, material characterization, scaffold for regenerative medicine and tissue engineering, synthetic vector for drug and gene therapy and stem cell engineering are introduced and explained. Unfixed ( Please ask the instructors about schedule) The objective is to understand how novel polymeric materials are studied and developed, and to learn how to read, summarize, and write a research paper. Survey of newly published paper related to new materials will be done as required. Student will be asked to read and explain the paper in the research group seminar. Seminar Thursday, Every week, 17:00-20:00 The objective is to learn the skill necessary for the research of functional materials (polymer synthesis, characterization, cell culture and animal experiment) Participation in a research group Any time 3 parts of lecture will be held. Please ask to contact person. room will be informed by contact person. Scoring will be done by the result of attendance and the achievement of the report. 6.Notes: -9-

16 Oral Radiation Oncology (Code:8081,1 st -year : 6 units) (Code:8082,1 st -~2 nd -year: 4 units) (Code:8083,2 nd -~3 rd -year: 8 units) Professor Masahiko MIURA Contact person Masahiko MIURA masa.mdth@tmd.ac.jp Oral Radiation Oncology is a branch of radiation oncology dealing with basic radiobiology, translational research, and radiotherapy for oral cancer. Main objective of this branch in the graduate course is to provide opportunities to study biological strategies for radiosensitization, development of radiosensitizers, molecular mechanisms of tumor radioresistance, the state of the art technology of radiotherapy, and basis of individualized radiotherapy depending on each student s research projects. Special Oct. 16- Dec. 25, 2014 on every Thurs. 8:00am-9:00am Molecular Biology for Radiation Oncology 1week(around the end of Sep.) at Tamachi Campus, Tokyo Institute of Technology Training Program for Specialists in Cancer:Radiation Biology Course Every Other week on Thurs. 8:00am-9:00am Journal Club Research in Progress Every Other week on Thurs. 8:00am-9:00am Reading by turns Every Tues. 8:00am-9:00am The outline of is to diagnose varying types of the primary and locoregional sites of oral cancer and to learn how to treat them by radiotherapeutic modalities including 3D-conformal radiotherapy, brachytherapy, and multidisciplinary treatments. Clinical Conference Every other week on Fri. The outline is to learn basic techniques required for our research themes (tissue culture techniques, X-ray irradiation, radiation dosimetry, Western blotting, gene transfer, real time imaging using fluorescent proteins, etc.) Participate in each research group To give lectures and practice in front of small number of students. To cultivate ability to extract problems and constitute your own notion through discussions. Make sure by contacting me before each lecture or seminar Totally evaluate students achievements based on the presence to lectures or seminars and research activity. -10-

17 Oral and Maxillofacial Surgery (Code:8091,1 st -year : 6 units) (Code:8092,1 st -~2 nd -year: 4 units) (Code:8093,2 nd -~3 rd -year: 8 units) Associate Professor : Hiroyuki Harada, Junior Associate Professor : Yuji Kabasawa, Eriko Marukawa Part-time lecturer: Yutaka Maruoka, Yusuke Nakajima Contact person: Oral and Maxillofacial Surgery Hiroyuki Harada hiro-harada.osur@ tmd.ac.jp The program is designed for understanding the broad knowledge and basic skills which are important for diagnosis, treatment, prognosis and prevention of oral and maxillofacial diseases. As needed Special As needed Seminar As needed Staff conference Every Thursday 18:00 to 20:00 The program is designed for understanding the clinical, imaging and pathological features which are important for diagnosis of oral and maxillofacial diseases. And the program is designed for determining the optimal treatments considering cosmesis and functions and practicing them in both outpatient and inpatient clinics. Conference for new patients Every Monday 16:30 to 17:30, Every Wednesday 16:30 to 17:30 Special clinic and conference for oral cancer Every Tuesday 13:30 to 16:00, Every Friday 11:00 to 14:00 Conference with Department of Diagnostic Radiology and Oncology Every other Friday 18:00 to 19:00 Conference for oral cancer Every Friday 18:00 to 20:00 Conference for facial deformities Second and third Friday of every month 15:00 to 16:00 Preoperative conference Every Thursday 17:00 to 18:00 Participate in research in the following fields, and learn the basic methods and skills for experimentation. 1. Molecular biological research related to invasion and metastasis of oral cancer. 2. Research related to dysfunction and QOL following oral cancer surgery. 3. Research related to distraction osteogenesis. 4. Research related to mandibular reconstruction through tissue engineering. 5. Research related to cleft palate and cleft lip bone grafting. Small groups with maximum opportunity for discussion. Seminar room of the Department of Oral and Maxillofacial Surgery (Faculty Building of University Hospital of Dentistry, 9 th floor). However, please confirm the location in advance with the instructor. Evaluation is based on participation (attendance) in lectures, practices and labs and on acquisition of skills and knowledge, and it is added to an evaluation when there is a presentation at the academic -11-

18 Oral and Maxillofacial Radiology (Code:8101,1 st -year : 6 units) (Code:8102,1 st -~2 nd -year: 4 units) (Code:8103,2 nd -~3 rd -year: 8 units) Professor: Tohru Kurabayashi Associate Professor: Hiroshi Watanabe Junior Associate Professor: Naoto Ohbayashi, Norio Yoshino Assistant Professor: Akemi Tetsumura, Shin Nakamura, Ami Kuribayashi, Jun ichiro Sakamoto Contact person: Tohru Kurabayashi kura.orad@tmd.ac.jp Main objective is to provide students opportunity to study advanced imaging modalities including digital imaging, cone-beam CT, multi-detector row CT and MRI. in the first semester Special uncertain (depending on the schedule of the lecturer) Seminar in the first semester Journal Club Thursday, 17:00-18:00 Conference Wednesday, 8:20-8:50 The goal of the practice is mainly to obtain the professional skills of interpreting both conventional and sectional images of dento-maxillo-facial region. Clinical training: any time (depending on the schedule of the instructors and students) The main objective is to learn how to plan clinical research concerning imaging diagnosis and analyze the data. Students can participate in any research group in Oral and Maxillofacial Radiology. The format depends on the instructor who teaches the students. Oral Radiology Department of Dental Hospital (B1 floor) or laboratories of Oral and Maxillofacial Radiology (9 th floor) The attitude of the students in each program will be evaluated. 6.Notes: s are mostly held in Japanese. -12-

19 Anesthesiology and Clinical Physiology (Code:8111,1 st -year : 6 units) (Code:8112,1 st -~2 nd -year: 4 units) (Code:8113,2 nd -~3 rd -year: 8 units) Contact person: Professor and Chair Haruhisa Fukayama fukayama.anph@tmd.ac.jp Learners will consider generally the basic knowledge of local anesthesia, general anesthesia, psycho-sedation, systemic management and pain control in dentistry, and establish the basements of specialists in anesthesiology and clinical physiology. Learners will acquire the pharmacological action and action mechanism through discussion, clinical settings and research works. The aims of this course were to clarify the neuro physiological pain mechanisms and their modulation ways, and to develop the new pain control methods and new local anesthetic methods. The other aims are to investigate the pain relative intrinsic biologically active substance and to clarify the mechanism of refractory pain diseases using molecular biology methods, and finally to establish the new treatment methods. any time Special all time Seminar any time Journal Club Every Thursday (17:00-18:00) Conference Monday to Friday (10:30am -12:00am) Learners will acquire the physiological and pharmacological basic knowledge and methods in dental clinical settings of local anesthesia, general anesthesia and psycho-sedations, and also learn pathology of pain diseases. Presentation of research at any time Clinical practice assigned Research in clinical settings The aims of the course are to establish and develop the non-invasive percutaneous and per mucosal drug delivery, and also clarify the pain mechanism and develop their managements. The reaction to the pain of living body will be studied. Learners are available to join the following research groups. 1) Research of mechanism in Diffuse Noxious Inhibitory Controls 2) Research in Drug delivery system 3) Research in relation between pain and autonomic nervous system 4) Research of occurrence mechanism of neuropathic pain. -13-

20 Learners will be able to attend the seminars, clinical conferences and special lectures available at any time. Seminar attendants will present and discuss about their own research process. Clinical conference attendants will be trained in clinical settings in assigned days. Learners must confirm the venues before attending the seminar, conferences and lectures, because the different places may be used The course attendants will be generally assessed in the base of their attitudes to the lecture, seminar, and laboratory work including their attendance and achievement of their research. 6.Notes: -14-

21 Orofacial Pain Management (Code:8121,1 st -year : 6 units) (Code:8122,1 st -~2 nd -year: 4 units) (Code:8123,2 nd -~3 rd -year: 8 units) Prof. Shimada Masahiko Contact person: Prof. Shimada Masahiko mshimada.ofpm@tmd.ac.jp Main objective of orofacial pain management in the postgraduate course is to lecture on the basis of the diagnosis and treatment of the disease with a pain, abnormal sensation, sensory paralysis, abnormal movement and motor paralysis in the orofacial area, in particular, mechanism of pain, neuropathic pain, so on. 16:00~17:00, every Monday from Oct to Nov. Special A special lecture has been irregularly held. Seminar A seminar has been irregularly held. Journal Club The fourth Wednesday every month, 18:00~19:00 Oriental oral medicine Seminar The fourth Wednesday every month, 18:00~19:00 The purpose of practice is to study the basis of the diagnosis and treatment of the disease with a pain, abnormal sensation, sensory paralysis and motor paralysis in the orofacial area Clinical Conference has been held the fourth Wednesday every month, 18:00~19:00 Clinical training has been performed on Monday, Tuesday, Thursday, Friday, 9:00~12:00 The main goal is to plane the design of Experiment concerning pain and abnormal sensation. Participation in the research group would be possible at any time. It is basically assumed the few people system. The place for debating is installed as much as possible to improve the interrelation with the student. Confirm it to the charge contact person. An integrated evaluation is done based on the participation situation to the lecture and research content. 6.Notes: None -15-

22 Pediatric Dentistry 1. Instructors: Junior Associate Professor: Yoshiaki Ono Contact person: Yoshiaki Ono y-ono.dohs@tmd.ac.jp (Code:8131,1 st -year : 6 units) (Code:8132,1 st -~2 nd -year: 4 units) (Code:8133,2 nd -~3 rd -year: 8 units) This lecture will guide students to understand the oro-facial functions, such as sucking, mastication, swallowing, and articulation, being developed and acquiered from newborn period to childhood as well as growth and development of the surrounding tissues and organs in this region. Students are also taught pathogenesis and pathophysiology of the diseases that disturb development and acquirement of these functions. Students will study theory and methodology not only for the developmental guidance of the oro-facial functions but also for diagnosis, prevention and treatment of related diseases and malfunctions. : According to the schedule of the graduate school. Special lecture : According to the schedule of the graduate school. Seminar : Paper reading : Tuesday 16:30~17:30, Friday 13:00~14:00 Conference : Friday 17:00~18:00 The comprehensive dental practice for child patients will guide student to understand the developmental processes of the oro-facial functions, and to study the outline of the method for diagnosis, prevention and treatment of the related diseases and malfunctions. The practice will also provide students to learn theory and method for the developmental guidance of these functions in the clinical viewpoints. Clinical conference : Friday 18:30~19:00 The students will analyze the developmental processes of the oro-facial functions as well as the growth processes of the related organs by the morphological, physiological and biological aspects to develop the method for the developmental guidance of these functions. The students also analyze pathogenesis and pathophysiology of the diseases that disturb development and acquirement of these functions to develop new methods for the treatment and prevention of the diseases. The students can join any research groups at any time. Research theme: 1) The study on the physiology and molecular biology of the oro-facial functions of children. 2) The morphological and biochemical study on the development and developmental disturbances of teeth -16-

23 3) The morphological study on the growth of dental arches, occlusion, jaws and face 4) The study on the development of new materials and methods for the dental treatments of child patients 3. Format Seminar style 4. Venue Unfixed. The students are advised to make a contact with the instructor in advance. 5. Grading Be assessed by the attendance/activities in the class and the research planning of each student. Any research report or paper presentation in a meeting will also be used for the assessment and grading. -17-

24 Orthodontic Science (Code:8141,1 st -year : 6 units) (Code:8142,1 st -~2 nd -year: 4 units) (Code:8143,2 nd -~3 rd -year: 8 units) 1. Instructors: Takashi Ono, Professor and Chairman Contact person:takashi Ono, Orthodontic Science t.ono.orts@tmd.ac.jp Goals: Orthodontic Science is one of the dental sciences which propose to control teeth, periodontium, and craniofacial growth and development in equilibrium with the whole body, and also deals with the prevention and/or treatment of malocclusion and related disorders, by which the alteration of maxillofacial function with aging could be kept to the most suitable condition. Outline: 1) To explain the unhealthy physiological condition of malocclusion and deepen the scientific basis for orthodontic treatment. 2) To understand the biological reaction and adaptation of occlusal tissues to mechanical stresses such as occlusal force or orthodontic force, and also the changes with aging. 3) To explain the art for controlling the morphologic and functional problems of occlusion in orthodontic treatment, from the view points of biomaterials and biomechanics. 4) To enlighten the social dentistry for the needs and demands of orthodontic treatment. Special Seminar as needed as needed as needed To understand the alteration of occlusal function and morphology, and to explain the pathological condition of malocclusion from the viewpoint of physiology, biomechanics, biology and sociology. Training for clinical examination as needed Clinical practice (see patients) 4.5 hour/week Clinical study by observation (treatments, diagnoses) every Tuesday and Friday, 9:00-12:00 Clinical Conference as needed Training for diagnosis and treatment planning as needed (basic skill, typodont) Seminar for Sociology as needed Department Seminar every Wednesday and Friday, 17:00-19:00 To understand the procedure of biological reaction and adaptation of occlusal system to the orthodontic stimuli, including the influence of aging, and to provide the control of the surroundings of the occlusal system. Progress meeting Research seminar as needed as needed -18-

25 3. Format: Generally in a small class. 4. Venue: Contact to the person in charge beforehand. 5. Grading: Students will be evaluated comprehensively according to the substances and participation in the lecture, practice and lab work. 6. Notes: The final evaluation will be held in the end of every year to acknowledge the promotion or graduation. -19-

26 Cariology and Operative Dentistry (Code:8151,1 st -year : 6 units) (Code:8152,1 st -~2 nd -year: 4 units) (Code:8153,2 nd -~3 rd -year: 8 units) Professor: Junji Tagami, Associate professor Masayuki Otsuki r: Toru Nikaido, Masatoshi Nakajima, Alireza Sadr, Shoji Nakashima, Yasunori Sumi, Nobuhiro Hanada, KairulMatin, Iori Sugita Assistant professor :Yasushi Shimada, Yuichi Kitasako, Takako Yoshikawa, Go Inoue, Keiichi Hosaka, Tomohiro Takagaki, Rena Takahashi, Noriko Hiraishi Contact person: Masayuki Otsuki otsuki.ope@tmd.ac.jp The goal of this course is to acquire the knowledge about the dental caries including diagnosis, prevention, treatment and restorative materials and to integrate it based on operative dentistry. at 17:40- on Wednesday in April December, at 15:00pm- on Wednesday in January to March English will be used in all lectures Special to be announced Seminar to be announced The goal of this course is to understand basic and clinical research about carioloy and operative dentistry and to form a research project of own research. group discussion practice of presentation The goal of this course is to master the experimental technique to perform own project. participation in each research project group and are organized in small group. to be announced Scored by attendance, report and/or examination 6.Notes: To take is required for participation in and. -20-

27 Fixed Prosthodontics Professor: Hiroyuki Miura Associate Professor: Keiichi Yoshida r: Daizo Okada,Wataru Komada Assistant Professor: Chiharu Shin, Shiho Otake, Kouichiro Yusa, Naosuke, Kumagae, Reiko Ogura Adjunct instructor: Eiichi Bando, Keiichi Sasaki, Masanori Nakano Contact person: Daizo Okada (Code:8161,1 st -year : 6 units) (Code:8162,1 st -~2 nd -year: 4 units) (Code:8163,2 nd -~3 rd -year: 8 units) Integrated learning of matters related to recover and maintain proper eating functions. Commentary from a biological standpoint on the methods for recovering from functional and cosmetic disturbances of oral and maxillofacial area caused by defect and loss of teeth every Wednesday (17:30 18:30) Special A/N Seminar A/N Journal Club every Thursday (17:00 18:00) Conference A/N Learning of mandibular movements and reproducibility of mandibular movements on the articulator Learning of mechanism of semi-adjustable articulator and its effect on occlusal surface configuration of prosthetics training seminars for new recruits A/N Learning of objective diagnosis method of oral functions Learning of experimental methodology for measurements of mandibular movements, and masticatory efficiency and functional testing of occlusal functions (tooth contact, tooth displacement, occlusal force) Participation in a research group A/N Small group instruction Refer to contact person Comprehensive evaluation based on the research content and the record of attendance at lecture, practice and lab 6.Notes: n.p. -21-

28 Pulp Biology and Endodontics (Code:8171,1 st -year : 6 units) (Code:8172,1 st -~2 nd -year: 4 units) (Code:8173,2 nd -~3 rd -year: 8 units) Associate Professor: Mitsuhiro Sunakawa Junior Associate Professor: Atsushi Takeda, Hideharu Ikeda Assistant Professor: Arata Ebihara, Nobuyuki Kawashima, Hiroyuki Matsumoto, Reiko Wadachi, Noriyuki Suzuki, Satoshi Watanabe, Jun Kawamura Part-time r: Tomoo Anjo, Satomi Takahashi, Yosuke Hayashi Contact person: Hideharu Ikeda, Pulp Biology and Endodontics, hms-ikeda.endo@tmd.ac.jp Graduate students are educated for immunology, physiology, bioengineering, imaging and lasing of the dentin/pulp complex and periapical tissue that are in normal or diseased conditions. Every Friday from October to December 10:00~12:00 Special as needed Seminar as needed Journal Club Every Thursday 16:30~17:30 All students are asked to exercise endodontic problem-solving of various clinical cases, including diagnosis and management of dental pain, preservation of the tooth pulp, strategies to deal with the complex root canal system, and surgical endodontics. Clinical Conference Every Thursday 17:30~18:30 All students can participate in various research programs, such as laser application to endodontics, immunohistochemistry electrophysiology. Participation in a research group as needed Sufficient question and discussion time is allocated for the student to actively engage in the above programs. The lectures are presented in 3 rd Room on the 2nd floor of Building 7 (Faculty of Dentistry and Animal Research Center Building). The venues for the other programs will be announced during the lecture course. Grade-point evaluation (4, 3, 2, 1, 0) is made for each student at the end of the course, based on the efforts made by the student toward the lecture, practice and lab. 6.Notes: All lectures are presented in English. -22-

29 Removable Partial Prosthodontics (Code:8181,1 st -year : 6 units) (Code:8182,1 st -~2 nd -year: 4 units) (Code:8183,2 nd -~3 rd -year: 8 units) Contact person: Noriyuki WAKABAYASHI (Professor), wakabayashi.rpro@tmd.ac.jp / Aims/outline: The Removable Partial Prosthodontics provides an advanced course in current status of arts and sciences of the field. The postgraduate students who are enrolled concurrently in wide range of oral health sciences are welcomed to our class. The aim of this course is to establish students knowledge including clinical pathology of tooth loss and the characteristics of oral tissues subjected to the prostheses and evaluation of the dental biomaterials. Goals/Objectives: The program objectives are to provide modern Prosthodontics research methods and to equip students to critically analyze research outcomes. Removable Prosthodontics for partially edentulous Patients rs Noriyuki Wakabayashi, Kenji Fueki, Takeshi Ueno, and Ichiro Minami Term Every Monday: 6.Oct~ 1.Dec Time 17:00~18:30 Room Room in Prosthodontics, 3F of Dental School Building (Building 7), Yushima Campus Special Anytime Seminar Anytime The aim of the practice is to introduce, realize and argue the scientific papers for further understanding to get the knowledge of the science and practice related to the Prosthodontics. It is our keen objective to learn and realize how to read, write and criticize the papers related to the prosthodontics. Every candidate is requested to read and introduce the classical and newest papers in turn to all the rest members of the candidates with arguments. The aim of the labo-work is to analyze and verify the denture dynamics in function for designing Removable Partial Dentures. Every candidate is requested to be accustomed to handle the ME apparatus to record various phenomena including denture dynamics. Every candidate has to address his or her opinion freely to the others. Verifying the lecture room is necessary according to the program executed. Comprehensive assessment is planned based on the presence, practice and labo-work and the completion of the theme. 6.Notes: Notice to our website for change of schedule and lecture hall

30 Oral Implantology and Regenerative Dental Medicine (Code:8191,1 st -year : 6 units) (Code:8192,1 st -~2 nd -year: 4 units) (Code:81932 nd -~3 rd -year: 8 units) Contact person: Shohei Kasugai TEL kas.mfc@tmd.ac.jp Prosthetic treatments with dental implants (dental implant treatment) for edentulous patients have been effective and predictable. The students will be able to learn the characteristics of dental implant treatments and dental implant materials and renew knowledge concerning all steps in dental implant treatment including clinical examinations, treatment planning, implant surgery, prosthodontics procedures and maintenance. In dental implant treatment bone augmentation and soft tissue management are frequently required. In this course, regenerative treatments, which relate to dental implant treatment, will be presented and discussed. Especially, future possibility of regenerative medicine in dental field will be discussed. The purposes of this course are to understand current dental implant treatment and its related regenerative dental medicine and to predict the future directions of researches in this field. Thursday 18:00 19:30 Special to be announced Seminar and Journal Club Monday 7:30-8:30, 18:00-19:00 Conference Friday 18:00 19:00 The purpose of this program is to understand the points in all steps of dental implant treatment: Clinical examinations, surgery, prosthetic procedures and maintenance. Several clinical cases will presented and treatment planning of these cases will be discussed. Clinical Conferences Monday Thursday 17:30-18:30, Friday 18:00-19:00 The purposes of this course are to clarify current clinical problems in dental implant treatment and to learn basic concept of plan researches to solve these problems. The researches, which are currently conducted by students in Department of Oral Implantology and Regenerative Dental Medicine, will be presented. The participants of this course will have chances to see animal experiments concerning dental implants and its related regenerative medicine. to be announced s by the instructors and presentations by the participants regarding the given subjects The forth seminar room (7 th building, 6 th floor), The demonstration room (7 th building, 3 rd floor), Dental Implant Clinic (Dental Hospital, 7 th floor), Animal Facility, based on attendance and attitude. 6.Notes: and journal club are in English. Students having interests in this field are welcome. Students are encouraged to participate in discussions actively. -24-

31 Plastic and Reconstructive Surgery 1. Instructors: Professor Mutsumi Okazaki r Hikoki Moki Contact person: Mutsumi Okazaki, Professor okazaki-plas@tmd.ac.jp (Code:7011, 1styear:6units) (Code:7012, 1st~2ndyear:4units) (Code:7013, 2 nd -~3rdyear: 8 units) Goals: To recognize meaning and necessity of plastic surgery, and to understand objective disorders and treatments for them. Outline: Explaining concepts of 4 major objectives of plastic surgery, 1: Conjenital anomaly, 2: Traumatic deformity, 3: Deformity after tumor resection and 4: Aesthetic surgery. Furthermore, explaining basic techniques (excision & suture, skin graft, flap transfer and other tissue transplantation) and advanced techniques (microsurgery and craniofacial surgery ) as therapeutic modality for objective disorders. 8 PM-, As needed Special As needed Seminar As needed Journal Club Every Tuesday 19:30~20:00 Goals: To decide a suitable treatment for each disorder, to handle surgical instruments and sutures correctly and to explain selected therapeutic procedures logically and perform them. Outline: Diciding a therapeutic strategy for each case in preoperative conference, and participating in operations. Preoperative case conference Every Tuesday 18:00~19:00 Postoperative case conference Every Tuesday 19:00~19:30 Research conference Occasional Tuesday 20:00~21:30 Photo conference Every Wednesday 8:00~9: 30 Ward round Every Weekday 9:00~12:30 17:00~18:00 Operation Every Monday 9:00~17:00 in main oprerating room Every Tuesday 9:00~17:00 in main oprerating room Every Wednesday 9:00~17:00 in main oprerating room Every Thursday 9:00~17:00 in main oprerating room Every Friday 9:00~17:00 in main oprerating room Goals: Revealing disease mechanism of objective disorders of plastic surgery, and developing new therapeutic approaches based on experimental results. Outline: Acquiring techniques for experimentation and analyzing obtained experimental data. Participation in a research group As needed Experimentation of plastic surgery Contents 1) Microsurgery 2) Vascularized free tissue transfer 3) Cartilage reproduction 4) Culture of keratinocyte and fibroblast 5) Evaluation of blood supply to various flaps using ICG. 6) Analysis of volume and blood supply to the flaps using nano-spectrum CT. -25-

32 3. Format: Small-group session is adopted in order for intense discussion. 4. Venue: Confirm to the instructor in charge before lecture. 5. Grading: Grade is given based on attitude to lectures, practices and labs and research outcome. 6. Notes: Journal club and research conference are expected to be held within 5 people, though the number of attendance is not limited. 7. Reference Books 1) Grabb & Smith Grabb and Smith's Plastic Surgery (7 HAR/PSC) Thorne, Charles H., M.D. (EDT)/ Chung, Kevin C., M.D. (EDT)/ Gosain, A 2) Plastic Surgery, 3rd ed., in 6 vols. With Expert Consult Premium Edition P.C.Neligan(ed.) 3) Essentials of Plastic Surgery, Second Edition Jeffrey E. Janis ed. -26-

33 Head and Neck Surgery 1. Instructors: Junior Associate Professor: Takuro Sumi Contact person: Takuro Sumi Department of Head and Neck Surgery (Code:7021, 1styear:6units) (Code:7022, 1st~2ndyear:4units) (Code:7023, 2 nd -~3rdyear: 8 units) : We mainly deal with head and neck tumours. s are focused on the clinical characteristics and pathogenesis of these head and neck tumours. Furthermore, various treatments strategies for these tumours are shown. Available programmes: : as needed Special : as needed Seminar: monthly, as needed Journal Club: every Tuesday, 8:20 9:00 There are three goals: First, to master the diagnostic techniques for head and neck tumours, by means of physical and endoscopic examinations. Second, to understand the findings of imaging utilities, such as X-ray, CT, MRI and US. Third, to properly select the appropriate treatments for head and neck tumours in consideration of function and appearance. Available programmes: Conferences: Outpatients with head and neck tumours: every Thursday 17:30 18:30 Inpatients with head and neck tumours (joint with plastic surgeon and neurosurgeon, as needed): every Tuesday 18:30 20:00 The patients who receive radiation therapy (joint with radiologists): biweekly Thursday 18:00 18:30 Ward rounds: every Tuesday 9:00 11:00 (1) Anatomy of the skull base. (2) Development of new surgical techniques in cancer treatment. (3) Clinical application of new devices in endoscopic examination. (4) Surgical treatment of paediatric head and neck tumours. Available programme: Participation in each study group: as needed 3. Format: The format comprises a small number of students. 4. Venue: Depend on the programme. 5. Grading: The evaluation of results is based on contents of reports, presentations at conference and original articles. -27-