Course No. 00333280 will lead you Computational Biology / Bioinformatics? NIH Computational Biology (The development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems. ) Bioinformatics (Research, development, or application of computational tools and approaches for expanding the use of biological, medical, behavioral or health data, including those to acquire, store, organize, archive, analyze, or visualize such data.) Bioinformatics Computational Biology
Walter Gilbert (1932- ) Harvard University W. Gilbert, Towards A Paradigm Shift in Biology, Nature, 1991
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2001 2 15 Nature 2001 2 16 Science At the White House on June 26, 2000, Francis Collins (r), Director of the National Human Genome Research Institute, President Clinton, and J. Craig Venter, President of Celera Genomics, lauded the thousands of scientists who contributed to the genome sequence.
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17,075 (Archaea) 202 (Archaeal virus) 66 (Bacteria) 3,316 2 (Eukaryo) 179 (Virus) 4,026 (Viroid) 60 (Phage) 2,010 (Organelle) 6,149 (Plasmid) 1,067 http://www.ebi.ac.uk/genomes/ 2015 9
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5 The Sun, the Genome, and the Internet Tools of Scientific Revolution Freeman Dyson HGP HGP Pandora's Box It s never the same!
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Walter Gilbert (1932- ) Harvard University, Biological Laboratories W. Gilbert, Towards A Paradigm Shift in Biology, Nature, 1991 / 2121 /
Bioinformatics Dr. Hwa A. Lim 1987 Bio-informatique Bioinformatics 1955 University of Texas at DallasAdjunct Professor 1981 Imperial College, London University 1986 Rochester University 30 1992 1995 1997 D Trends / / DNA RNA DNA
When I give talks to young scientists seeking advice about areas of future intense scientific excitement, computational biology is my number one recommendation. Francis Collins, Director of HGP at NIH The next step in the project is the interpretation phase. That is really the fun part of the whole project because then we finally have the complete order of all layers of genetic codes and we have to discover what it all means. J. Craig Venter, Head of Celera Genomics Inc.
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Predict the dynamics of systems so that the validity of the underlying assumptions can be tested. 1 2 (Computation) (System Analysis) (New Biotechnologies) (Systems Biology) (Experimental Data)
System Nodes Edges (Systems Biology) (General Biology) (Experimental, Theoretical, Computational Biology ) (Biotechnology)