10-15 s ~ W /cm 2 40 ~ Food and Drug Administration FDA Holger Lubatschowski Helmholtz Laser-Assisted in situ Keratomileusis LASIK

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1 DOI: /j.issn * 16% % 51% R312 R776 A Updates on the Study of Femtosecond Laser-Assisted Lens Surgery ZHANG Jia-ying 1 WEI Zhi-yi 2 GU Ying 1* 1. Department of Laser Medicine The General Hospital of PLA Beijing China 2. Chinese Academy of Sciences Institute of Physics ABSTRACT Femtosecond fs laser has been used to make slides inside crystalline lens to cut off stiff collagenous fibers for presbyopia treatment since Study results showed that porcine lens' deforming force was raised by 16% in average after such cut-off and rabbits' lens transparency and retina structure were not affected in 6 months after the operation. Fs laser was also used to make corneal incision cut anterior lens capsule and crash lens core in fs laser-assisted cataract surgery. Study results illustrated that anterior lens capsule was cut more smoothly and roundly with fs laser than by hand. The position of IOL was right in the center. Phaco energy was reduced by 43% and operating time was shortened by 51% after lens core was dealt with by fs laser. The complications were slight. Key words Femtosecond laser Cataract surgery Presbyopia Cut M YQ ~ * 399

2 10-15 s ~ W /cm 2 40 ~ Food and Drug Administration FDA Holger Lubatschowski Helmholtz Laser-Assisted in situ Keratomileusis LASIK ~ nm 100 khz nm 100 fs Krueger 1 Myers 1998 photophaco modulation photophaco reduction 5 khz A x-y 2009 F-theta 5 μm 2 z 1 mm 1. 5 mm 1B W /cm

3 6 2 Fisher rpm CCD ± 14 μm Fisher rpm 16% FDA Er YAG Nd YAG LenSx 55% LensAR Optimedice ± D 85% ± D 8 45% ± D 6% D

4 / Krueger RR Sun XK Stroh J et al. Experimental increase in accommodative potential after neodymium yttri- 11 um-aluminum-garnet laser photodisruption of paired cadaver lenses J. Ophthalmology % 51% 1 2 Nagy Z Takacs A Filkorn T et al. Initial clinical evaluation of an intraocular femtosecond laser in cataract surgery 1 2 J. J Refract Surg LASIK 3 F. Dausinger F. Lichtner H. Lubatschowski. Femtosecond Technology for Technical and Medical Applications J. Topics Appl. Phys mm 4 Ronald R. Krueger Jerry Kuszak Holger Lubatschowski et al. First safety study of femtosecond laser photodisruption in animal lenses Tissue morphology and cataractogen- esis J. J Cataract Refract Surg Tammo Ripken Uwe Oberheide Michael Fromm et al. fs-laser induced elasticity changes to improve presbyopic lens accommodation J. Graefes Arch Clin Exp Ophthalmol Silvia Schumacher Uwe Oberheide Michael Fromm et al. Femtosecond laser induced exibility change of human donor lenses J. Vision Research LASIK 7 Holger Lubatschowski Silvia Schumacher Michael Fromm et al. Femtosecond lentotomy generating gliding planes inside the crystalline lens to regain accommodation ability J. J. Biophoton Gale RP Saldana M Johnston RL et al. Benchmark standards for refractive outcomes after NHS cataract surgery J. Eye Lond Murphy C Tuft SJ Minassian DC. Refractive error and visual outcome after cataract extraction J. J Cataract Refract Surg Nichamin LS Teuma EV. The use of femtosecond lasers to create corneal incisions abstract. In Program and Abstracts of American Society of Cataract and Refractive LASIK Surgeons Symposium on Cataract J. IOL and Refractive Surgery Boston Massachusetts. 11 Lingmin He Katrina Sheehy and William Culbertson. Femtosecond laser-assisted cataract surgery J. Current Opinion in Ophthalmology Liu X Kurtz RM Braun A et al. Intrastromal corneal - surgery with femtosecond laser pulses J. Conference on - Lasers and Electro-Optics OSA Technical Digest Series Optical Society of America Washington DC. 402

5 Heisterkamp A. Einsatz ultrakurzer Laserpulse in der refraktiven Laserchirurgie D. Dissertation Universitaet Hannover

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9 8 500 μm Fig. 8 Crashing lens core with fs laser in 500 μm spacing pattern CSTC CHINAINFO

[1-3] (Smile) [4] 808 nm (CW) W 1 50% 1 W 1 W Fig.1 Thermal design of semiconductor laser vertical stack ; Ansys 20 bar ; bar 2 25 Fig

[1-3] (Smile) [4] 808 nm (CW) W 1 50% 1 W 1 W Fig.1 Thermal design of semiconductor laser vertical stack ; Ansys 20 bar ; bar 2 25 Fig 40 6 2011 6 Vol.40 No.6 Infrared and Laser Engineering Jun. 2011 808 nm 2000 W 1 1 1 1 2 2 2 2 2 12 (1. 710119 2. 710119) : bar 808 nm bar 100 W 808 nm 20 bar 2 000 W bar LIV bar 808 nm : : TN248.4 TN365