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() () () () () BEIJING DOUBLE-CRANE PHARMACEUTICAL CO.LTD. DCPC 1 (010)64742227-681 (010)64399098 dawsonz@dcpc.com 1 (010)64742227-653 (010)64398086 mss@dcpc.com 1 1 100102 http://www.dcpc.com.cn mss@dcpc.com http://www.sse.com.cn 7 12008 3

A 600062 1997 5 16 2002 12 3 1100001510319 110105633796475 63379647-5 1 22 () 452,030,579.23 470,654,781.73 380,572,486.34 338,916,114.04 331,710,145.42 () 43,713,442.56 22,844,653.40-39,385.14 - -10,921,132.16-9,504,425.32-475,868.59-3,960,912.45 41,656,372.30 7 12008 4

() 2008 2007 (%) 2006 4,951,524,367.82 4,556,616,381.12 8.67 4,133,346,054.01 470,654,781.73 574,684,384.48-18.10 243,286,052.33 380,572,486.34 437,580,763.41-13.03 164,742,346.24 338,916,114.04 276,485,571.79 22.58 137,328,520.10 331,710,145.42 235,458,162.37 40.88 303,623,064.41 2008 2007 (%) 2006 4,269,021,556.27 3,673,463,375.38 16.21 3,281,450,804.56 3,079,544,847.79 2,197,472,998.62 40.14 1,829,802,388.43 2008 2007 (%) 2006 0.8191 0.9921-17.44 0.3735 0.8191 0.9921-17.44 0.3735 0.7294 0.6268 16.36 0.3113 % 12.36 19.91 7.55 9.00 % 13.91 21.73 7.82 9.19 % 11.01 12.58 1.57 7.51 % 12.38 13.73 1.35 7.66 0.6963 0.5338 30.44 0.6884 2008 2007 (%) 2006 6.4640 4.9821 29.75 4.1485 7 12008 5

() 1 () (%) (%) 1 2 195,149,052 44.244 +18,008,816 +22,803,520 +40,812,336 235,961,388 49.53 3 583,264 0.132 +17,328,774-583,264 +16,745,510 17,328,774 3.64 : 583,264 0.132 +17,328,774-583,264 +16,745,510 17,328,774 3.64 4 195,732,316 44.376 +35,337,590 +22,220,256 +57,557,846 253,290,162 53.17 1 245,343,384 55.624-22,220,256-22,220,256 223,123,128 46.83 2 3 4 245,343,384 55.624-22,220,256-22,220,256 223,123,128 46.83 441,075,700 100.00 +35,337,590 - +35,337,590 476,413,290 100.00 1) 583,264 4 25 2008 4 22 2) 18,008,816 233,662,703 36 (1) 2007 6 24 2007 9 21 2007 [2008]413 2008 4 29 (A ) 35,337,590 476,413,290 (2) 2008 4 29 7 12008 6

(3) 2008 2008 0.86 /5.49 / 2008 0.82 /6.46 / 2 192,850,367 40,812,336 233,662,703 583,264 583,264 2,298,685 2,298,685 (1) (2) 233,662,703 36 (1) (2) 354,473 20114 29 20084 25 4,000,000 4,000,000 12 20094 29 3,000,000 3,000,000 12 20094 29 2,500,000 2,500,000 12 20094 29 2,000,000 2,000,000 12 20094 29 2,000,000 2,000,000 12 20094 29 2,000,000 2,000,000 12 20094 29 1,828,774 1,828,774 12 20094 29 195,732,316 583,264 58,141,110 253,290,162 / / 7 12008 7

() 1 () 17,328,774 2009 4 29 2008 4 29 19.01 18,008,816 2011 4 29 2 476,413,290 253,290,162 () 1 3 () 1 11,250 (%) 49.05 233,662,703 +18,008,816 233,662,703 1.60 7,633,807 +2,034,083 1.39 6,599,625 +3,999,625 1.36 6,494,015 +491,783 1.07 5,090,930 +5,090,930 1.00 4,761,860 +56,978 0.93 4,441,590 +4,441,590 4,000,000 () 0.87 4,133,872 +4,133,872 0.67 3,206,682 +3,206,682 0.63 3,000,000 +3,000,000 3,000,000 7 12008 8

() (LOF) 7,633,807 6,599,625 6,494,015 5,090,930 4,761,860 4,133,872 3,206,682 2,916,525 2,747,200 2,699,719 7 12008 9

1 233,662,703 2011429 36 2 4,000,000 2009429 12 3 3,000,000 2009429 12 4 2,500,000 2009429 12 5 2,298,685 200746 (1) (2) 354,473 6 2,000,000 2009429 12 7 2,000,000 2009429 12 8 2,000,000 2009429 12 9 1,828,774 2009429 12 () 2008 4 29 2009 4 29 2008 4 29 2009 4 29 4,000,000 3,000,000 12 2008 4 29 2009 4 29 2 (1) 2,320,000,000 1987 3 28 7 12008 10

() (2) 16,467,063,500 2003 6 20 (3) (4) 7 12008 11

3 () : () 49 200653020095 30 48 200653020095 30 60 200653020095 30 51 200653020095 30 105.70 45 200653020095 30 51 200653020095 30 26,100 26,100 90.53 50 200653020095 30 21,300 21,300 81.27 65 200653020095 30 8.00 59 200653020095 30 8.00 54 200653020095 30 8.00 50 200653020095 30 8.00 59 200653020095 30 51 200653020095 30 51 200653020095 30 51 200653020095 30 23,521 23,521 48.20 49 200653020095 30 58.18 51 2006622009 62 95.27 45 2006622009 62 81.88 51 2006622009 62 15,200 12,000-3200 74.32 42 2006622009 62 90.72 45 2006622009 62 90.53 45 2006622009 62 89.36 42 2006622009 62 80.32 1,018.28 7 12008 12

5 (1) 2000 2002 (2) 1996 8 2000 11 ; (3) 1994 8 2004 12 (4) 2002 1 2004 10 2004 11 2005 1 2004 12 2005 1 (5) () (6) 1997 2003 4 (7) 1997 2003 (8) 1998 9 2003 2 2003 3 2004 7 (9) 1994 (10) (11) (12) () (13) (14) (15) (16) 7 12008 13

(17) 2001 7 2004 7 (18) 1991 2000 (19) 1985 2000 (20) 2000 12 2003 6 2003 6 2004 4 (21) 2001 4 2004 12 2004 12 (22) 1998 7 2003 12 () ()2004 1 2005 11 (23) 2000 6 2002 12 2003 1 2003 4 2003 5 2005 11 () 2002-07 2000-11 2004-12 2004-12 2004-12 2007-06 2001-04 2002-08 1998-03 2001 / / 1997-04 2008-06-27 7 12008 14

() 1 2: () 2008 2007 () () 9,977 0 1 6448 1767 1345 417 2 119 1063 1867 6928 () (1)2008 3 2007 12 28 2007 2008 1 21 2007 2008 1 30 2007 ()() 7 12008 15

(2)2008 6 2008 (3)2008 6 30 6 26 ( ) ([2005]34 (4) () 1 () () () 14 14 0 0 14 12 2 0 14 13 1 0 14 14 0 0 2 () 1 2 3 4 7 12008 16

5 () 1 ()() 2 3 2008 7 12008 17

4 5 2008 () 1 1 2 2 () 12008 4 8 2008 22008 6 6 2007 2008 4 10 6 10 www.sse.com.cn www.dcpc.com.cn () 3 () 2008 5 7 2007 2008 5 8 7 12008 18

() 2008 8 15 2008 2008 8 18 () 1 (1) 2008 2008 2008 490,734 38,057 33,171 (2) 2008 2008 490,734 9% ( 15.6) 38,057 17% 32% 12% 26% 9 2008 () 82% 1.5 96% 0 8 6.7% 42.5 21.5 26% : () 70,369 11,769 12.9% 19,556 7,018 5.2% 117,064 73,793 23.3% 45,331 21,048 6.84% 5 15 50% 7 12008 19

0 6% OTC 70 1.49 3.8% 2 (1) 2009 2009 GDP 8-9% 2009 20% 15%20% 2009 7 12008 20

(2) 2009 2009 500 1200 0 90% 2009 CGMP 44 8,059 60% 7 12008 21

(3) 2009 2009 ANDA FDA 3 (1) : : (%) () () (%) 2,523,188,429.00 1,136,279,220.82 54.97 15.60 17.88 0.87 2,384,147,565.97 2,247,774,325.20 5.72 3.27 3.09 0.16 4,907,335,994.97 3,384,053,546.02 31.04 9.26 7.62 1.05 ( ) 1,271,732,702.36 378,922,817.06 70.20 14.22 15.52 0.34 1,170,635,556.16 737,925,072.26 36.96 23.34 25.39 1.03 (2) : : () 93,833,891.43-1.16 1,659,146,332.33 11.98 2,404,034,063.13 2.92 875,553,390.71 37.65 197,446,924.63 21.09 265,069,207.01 30.91 333,130,781.20-3.22 92,344.00-89.32 5,828,306,934.44 10.82 920,970,939.47 4,907,335,994.97 10.47 7 12008 22

4 5 6 () 2 2,406 99% 2008 90% (%) 90 1 2008 67,176.76 34,321.78 34,321.78 31,254.37 1600.61 7 12008 23

2 PVC 22,234.76 22,234.76 100% 1109.02 682.77 35,021.00 8,529.64 24% 0 1,878.29 5,808.00 2,026.53 35% 0 400.00 4,113.00 1,530.85 37% 0 0 67,176.76 34,321.78 1 CGMP CGMP 2008 236.61 40.38% 95.54 2 3 4 GMP 3 (1) 43.50% 46.50% 2 ( 1 ) (2) 2008 2008 8,191 2 1 (3) 2008 2008 2,868 ( 2,000 2008 868 ) 1 GMP 7 12008 24

(4) 1 () (5) CGMP FDA-CGMP 6,236 ( 3,000 2008 3,236 ) GMP () () 1 2008-01-18 2008-01-31 2008-02-02 2008-03-07 2008-04-08 2008-2010 2008 2008 2008 3000 <> <> 2007 2007 2007 2007 2007 2007 2007 2007 2008 2007 2008 2007 2008-04-24 2008 2008-05-14 B08 D46 C039 14 D006 D42 B16 16 D017 D27 C047 52 B05 D15 2008 122 200822 2008 25 2008 38 2008 410 20084 12 20085 15 7 12008 25

2008-05-20 2008-05-23 2008-06-06 2008-07-28 2008-08-15 90% 2007 D003 D15 C020 14 D003 A19 < B02 ()><()> C12 <()> <()> <()> 2008 2008 CGMP 2008-09-22 2008-10-28 2008 2009 D017 A17 C11 C16 D014 C10 20085 21 20085 24 20086 10 20087 29 20088 18 20089 23 20081029 2 2007 2007 476,413,290 10 1.85 () 10 1.665 88,136,460.82 2008 6 16 2008 6 17 2008 6 23 3 2008 (1)2009 1 20 2008 (2) 7 12008 26

(3) 2008 (4) 2009 2 16 3 2 (5) 2009 3 27 (1) 2008 2008 (2) (6) 2009 4 21 (1) 2008 (2) 2008 (3) 2008 (7) 2009 4 24 2008 2009 2008 2009 4 () 2008 476,413,290 10 2 95,282,658.00 64,315,794.15 0.135 159,598,452.15 577,616,528.76 2008 () () (%) 2005 79,393,623.97 185,147,485.74 42.88 2006 70,572,109.88 158,355,502.93 44.57 2007 88,136,460.82 355,664,445.67 24.78 7 12008 27

() 2008 1 18 2008 2 2 2008 4 8 2008 4 24 2008 6 6 2008 7 28 2008 8 15 2008 10 28 2008-2010 2008 2008 2008 3000 2007 2007 2007 2007 2007 2007 2007 2007 2007 2008 2007 2008 90% 2007 2008 2008 CGMP 2008 2009 () 2008 7 12008 28

() 2008 () 2008 671,767,585.90 () 2008 () 2008 () 1( ) 4416.69 700.34 2006 4 18 ( ) 2006 6 19 2007 1 29 2 2008 11 26 3GL ASIA MAURITIUS LTD(GL)( ) 2008 7 25 ( 38% )2003 710 2008 12 19 2009 1 932.113216 () 7 12008 29

() 1 () () 506.50-1.03% 506.50 2,000-2% 2,000 2,506.50 - - 2,506.50 () 1 ( ) ( ) : : (%) 43.50% 46.50% 2008-06-06 1 1-12,916,714.20-3% 90% 2 52.13% ( ) 2008-09-08 1-7,796,900.72 26,968,950.84 (%) -2% 1,200 7 12008 30

() 1 2008 2007-4,800,000.00-4,800,000.00 2 572.43 418.98 572.43 2,429.78 2,429.78 / 3,002.21 418.98 3,002.21 () 1 (1) (2) (3) 2 () 3000.00 3000.00 () 3000.00 (%) 0.95 70-50 - 7 12008 31

3 4 () 1 5% (1) 1 2 20052006 2007 2005 50% 3( ) () 4 5000 1 2005 2005 441,075,700 10 1.8 () 2006 6 30 2006 7 3 2006 7 7(2005 50%) 2 2006 2006 44,107.57 10 1.6 () 70,572,112.00 2007 6 8 2007 6 11 3 2007 2007 476,413,290 10 1.85 () 2008 6 16 2008 6 17 2008 6 23 4 2006 5 29 22,803,520 5.17% (2) 2007 [2008]413 ( 7 12008 32

) 4,000 8 (A ) 35,337,590 233,662,703 36 2008 4 29 2011 4 29 7 12 2008 4 29 2009 4 29 () : : 2,000,000.00 4 () () (1) 2008 8 21 33,263.12 () C08 A11 2008121 B08 D46 2008122 B08 D46 2008122 B08 D46 2008122 D016 D15 2008129 C039 14 200822 D006 D42 200825 D006 D42 200825 D006 D42 200825 www.sse.com.cn 7 12008 33

D006 D42 200825 B16 16 200838 D142 D126 2008326 20007 D017 D27 2008410 D017 D27 2008410 2008 D017 D27 2008410 2007 D017-018 D27 2008410 2008 C047 52 2008412 A20 D5 2008422 2008 C016 111 2008426 D007 A35 200855 2007 B02 D18 200858 B05 D15 2008515 D003 D15 2008521 C020 14 2008524 D003 A19 2008610 90% D003 A19 2008610 D003 A19 2008610 2007 D007 D19 2008611 2008 B02 C12 2008729 B02 C12 2008729 2008 D017- D018 A17 - A18 2008818 D017 A17 2008818 D017 A17 2008818 D017 A17 2008818 2008 D017 A17 2008818 2008 D017 A17 2008818 C11 C16 2008923 A16 10 20081011 2008 D014 C10 20081029 D014 C10 20081029 D014 C10 20081029 2008 D014 C10 20081029 7 12008 34

() (2009) 0817 () 2008 12 31 2008 (1) (2)(3) 2008 12 31 2008 2009 4 24 7 12008 35

() 2008 12 31 20081231 20071231 1 1,028,431,264.73 654,288,053.40 2 173,274,488.96 251,624,538.47 3 535,406,211.69 499,675,230.68 4 221,199,514.33 145,532,007.79 5 1,113,288.33 6 81,194,091.84 230,964,508.97 7 604,537,197.79 528,564,138.56 8 37,303,317.92-2,682,459,375.59 2,310,648,477.87 9 81,451,121.00 82,935,025.24 10 97,799,156.46 102,470,516.67 11 1,096,150,833.87 953,512,886.73 12 118,312,949.09 43,873,150.43 13 9,470,795.31 387,700.00 14 131,428,963.65 142,862,496.57 15 16,354,649.33 20,758,496.63 16 9,073,834.23 812,728.98 17 1,913,706.96 913,257.35 18 24,606,170.78 14,288,638.91 1,586,562,180.68 1,362,814,897.51 4,269,021,556.27 3,673,463,375.38 7 12008 36

() 2008 12 31 2008 12 31 2007 12 31 21 325,500,000.00 304,000,000.00 22 130,151,954.43 203,080,829.62 23 310,364,198.63 389,912,180.92 24 29,255,695.20 68,838,485.27 25 34,872,042.31 22,289,902.90 26 60,873,442.87 120,311,005.48-461,111.84 27 170,286,241.05 140,717,280.94 28 16,000,000.00 7,000,000.00-1,077,303,574.49 1,256,610,796.97 16,000,000.00-29 27,000,000.00 27,000,000.00 30 3,817,525.75 1,894,533.28 31 10,437,172.17 7,270,322.17 41,254,697.92 52,164,855.45 1,118,558,272.41 1,308,775,652.42 () 32 476,413,290.00 441,075,700.00 33 1,163,740,897.95 609,442,664.30 34 189,944,259.27 166,120,418.76 35 1,249,446,400.57 980,834,215.56 3,079,544,847.79 2,197,472,998.62 36 70,918,436.07 167,214,724.34 3,150,463,283.86 2,364,687,722.96 4,269,021,556.27 3,673,463,375.38 7 12008 37

2008 12 31 2008 12 31 2007 12 31 728,102,879.70 8,737,717.65 87,271,674.32 136,777,750.87 3 98,488,729.60 85,088,392.38 36,329,158.89 23,401,146.23 1,113,288.33 6,416,000.00 6 617,560,402.66 794,807,479.86 124,843,007.92 80,344,100.76 18,195,716.11 1,711,904,857.53 1,135,572,587.75 9 635,081,065.81 462,761,620.41 72,390,084.14 77,754,612.02 398,036,964.85 364,440,851.31 14,023,455.88 4,844,662.56 70,751,226.67 72,275,618.10 13,104,649.33 20,758,496.63 2,276,039.60 2,226,663.80 1,205,663,486.28 1,005,062,524.83 2,917,568,343.81 2,140,635,112.58 7 12008 38

() 2008 12 31 2008 12 31 2007 12 31 170,000,000.00 170,000,000.00 29,738,127.61 27,041,049.77 2,682,613.04 1,048,032.39 15,649,039.91 5,272,465.28 14,021,923.77 51,631,830.76 461,111.84 28,544,850.50 33,549,287.32 260,636,554.83 289,003,777.36-27,000,000.00 27,000,000.00 832,945.64 1,894,533.28 5,101,343.37 5,116,593.37 32,934,289.01 34,011,126.65 293,570,843.84 323,014,904.01 476,413,290.00 441,075,700.00 1,220,424,969.79 599,487,212.62 189,944,259.27 166,120,418.76 737,214,980.91 610,936,877.19 2,623,997,499.97 1,817,620,208.57 2,917,568,343.81 2,140,635,112.58 7 12008

2008 1-12 2008 1-12 2007 1-12 37 4,951,524,367.82 4,556,616,381.12 37 3,417,724,980.67 3,186,254,272.57 38 32,466,523.24 28,094,645.99 748,563,466.10 660,694,248.83 290,883,522.29 224,676,625.64 12,795,499.83 11,433,776.25 39 27,036,185.11 52,002,135.74 ( ) ( ) 40 29,976,388.65 304,236.77 278,652.30 ( ) 452,030,579.23 393,764,912.87 41 41,159,778.62 212,573,913.23 43 22,535,576.12 31,654,441.62 ( ) 470,654,781.73 574,684,384.48 44 74,199,339.32 117,077,185.93 ( ) 396,455,442.41 457,607,198.55 380,572,486.34 437,580,763.41 15,882,956.07 20,026,435.14 () 0.8191 0.9921 () 0.8191 0.9921 7 12008

2008 1-12 2008 1-12 2007 1-12 37 762,980,164.67 697,077,806.97 37 318,901,973.64 272,538,124.65 9,823,559.52 9,183,180.68 36,134,911.05 27,569,858.35 118,820,169.64 90,090,189.84 10,433,409.30 7,242,107.25-8,064,151.80 31,428,292.57 ( ) ( ) 40 3,480,992.24 86,877.44 ( ) 280,411,285.56 259,112,931.07 13,500,323.87 187,645,215.40 14,589,382.17 27,119,471.62 ( ) 279,322,227.26 419,638,674.85 41,083,822.21 63,974,229.18 ( ) 238,238,405.05 355,664,445.67 () 0.5127 0.8064 () 0.5127 0.8064 7 12008

2008 1-12 2008 1-12 2007 1-12 4,087,667,820.01 4,543,190,020.92 478,559.96-46 76,484,715.02 11,906,704.00 4,164,631,094.99 4,555,096,724.92 2,173,384,768.77 2,928,558,001.27 458,061,263.92 376,939,497.83 478,254,564.28 378,290,158.74 47 723,220,352.60 635,850,904.71 3,832,920,949.57 4,319,638,562.55 331,710,145.42 235,458,162.37 500,000.00 31,201.00 691,637.39 2,001,560.00 142,752,889.68 171,788,534.09 - - 48 14,805,820.01 13,004,229.82 158,750,347.08 186,825,524.91 309,201,343.32 136,172,576.04-24,055,400.00 - - 49 19,499,785.99-328,701,129.31 160,227,976.04-169,950,782.23 26,597,548.87 425,299,460.04 5,000,000.00-301,800,000.00 300,000,000.00-727,099,460.04 305,000,000.00 350,300,000.00 314,500,000.00 111,280,806.78 93,166,398.72-50 3,366,432.25 437,719.54 464,947,239.03 408,104,118.26 262,152,221.01-103,104,118.26-17,517.35 113,432.54 423,894,066.85 159,065,025.52 550,311,715.76 391,246,690.24 974,205,782.61 550,311,715.76 7 12008

2008 1-12 2008 1-12 2007 1-12 806,424,387.29 584,108,014.98 29,194.63-332,596,031.49 13,321,040.13 1,139,049,613.41 597,429,055.11 162,632,981.67 115,388,941.04 117,326,824.83 111,532,313.26 163,423,270.35 134,894,043.40 341,943,249.04 457,850,551.49 785,326,325.89 819,665,849.19 353,723,287.52-222,236,794.08 500,000.00 1.00 6,416,000.00 2,000,000.00 128,887,918.51 171,108,047.80 - - 1,984,326.67 3,541,603.38 137,788,245.18 176,649,652.18 28,182,338.29 46,056,897.25 76,317,800.88 24,055,400.00 - - - - 104,500,139.17 70,112,297.25 33,288,106.01 106,537,354.93 434,113,910.17 - - 170,000,000.00 170,000,000.00-604,113,910.17 170,000,000.00 170,000,000.00 170,000,000.00 100,643,918.61 80,056,133.04-353,872.67 169,985.43 270,997,791.28 250,226,118.47 333,116,118.89-80,226,118.47-17,517.35 113,432.54 720,109,995.07-195,812,125.08 7,899,493.29 203,711,618.37 728,009,488.36 7,899,493.29 7 12008

2008 1-12 441,075,700.00 609,442,664.30-166,120,418.76 980,834,215.56-167,214,724.34 2,364,687,722.96 - - 441,075,700.00 609,442,664.30-166,120,418.76 980,834,215.56-167,214,724.34 2,364,687,722.96 ( ) 35,337,590.00 554,298,233.65-23,823,840.51 268,612,185.01 - -96,296,288.27 785,775,560.90 () 380,572,486.34 15,882,956.07 396,455,442.41 () - 835,018.00 - - - - 113,301.27 948,319.27 1-2 10,437.00 10,437.00 3-4 824,581.00 113,301.27 937,882.27 ()() - 835,018.00 - - 380,572,486.34-15,996,257.34 397,403,761.68 () 35,337,590.00 553,463,215.65 - - - - -112,292,545.61 476,508,260.04 1 35,337,590.00 620,423,920.17 655,761,510.17 2-3 -66,960,704.52-112,292,545.61-179,253,250.13 () - - - 23,823,840.51-111,960,301.33 - - -88,136,460.82 1 23,823,840.51-23,823,840.51-2() -88,136,460.82-88,136,460.82 3 - () - - - - - - - - 1 () - 2 () - 3-4 - 476,413,290.00 1,163,740,897.95-189,944,259.27 1,249,446,400.57-70,918,436.07 3,150,463,283.86 7 12008

() 2007 1-12 : 441,075,700.00 608,780,707.64 238,700,497.51 526,986,635.89-1,815,543,541.04 - - - -108,146,523.32 122,405,370.71-173,856,505.56 188,115,352.95 - - - - - - - - 441,075,700.00 608,780,707.64-130,553,974.19 649,392,006.60-173,856,505.56 2,003,658,893.99 ( ) 661,956.66 35,566,444.57 331,442,208.96 - -6,641,781.22 361,028,828.97 () 437,580,763.41 20,026,435.14 457,607,198.55 () 661,956.66 661,956.66 1-2 - 3-4 661,956.66 661,956.66 ()() 661,956.66 - - 437,580,763.41-20,026,435.14 458,269,155.21 () - - - - - - -26,668,216.36-26,668,216.36 1-2 - 3-26,668,216.36-26,668,216.36 () 35,566,444.57-106,138,554.45 - - -70,572,109.88 1 35,566,444.57-35,566,444.57-2 -70,572,109.88-70,572,109.88 3 - () - 1-2 - 3-4 - 441,075,700.00 609,442,664.30-166,120,418.76 980,834,215.56-167,214,724.34 2,364,687,722.96 7 12008

2008 1-12 : 441,075,700.00 599,487,212.62-166,120,418.76 610,936,877.19 1,817,620,208.57 - - 441,075,700.00 599,487,212.62-166,120,418.76 610,936,877.19 1,817,620,208.57 ( ) 35,337,590.00 620,937,757.17-23,823,840.51 126,278,103.72 806,377,291.40 () 238,238,405.05 238,238,405.05 () 1 2 3-513,837.00 - - - 513,837.00 10,437.00 10,437.00 4 503,400.00 503,400.00 ()() - 513,837.00 - - 238,238,405.05 238,752,242.05 () 35,337,590.00 620,423,920.17 - - - 655,761,510.17 1 35,337,590.00 620,423,920.17 655,761,510.17 2 3 - () - - - 23,823,840.51-111,960,301.33-88,136,460.82 1 23,823,840.51-23,823,840.51-2 -88,136,460.82-88,136,460.82 3 - () - - - - - - 1-2 3-4 - 476,413,290.00 1,220,424,969.79-189,944,259.27 737,214,980.91 2,623,997,499.97 - - - - 7 12008

441,075,700.00 () 2007 1-12 608,780,707.6 4 : 183,238,552.6 8 607,941,283.36 1,841,036,243.68-9,293,495.02-52,684,578.49-246,530,297.39-308,508,370.90-441,075,700.00 ( ) 599,487,212.6 2-130,553,974.1 9 361,410,985.97 1,532,527,872.78 - - - 35,566,444.57 249,525,891.22 285,092,335.79 () 355,664,445.67 355,664,445.67 () 1 2 3 4 - ()() - - - - 355,664,445.67 355,664,445.67 () 1-2 3 - () 35,566,444.57-106,138,554.45-70,572,109.88 1 35,566,444.57-35,566,444.57-2 -70,572,109.88-70,572,109.88 3 - () 1-2 - 3-4 - 441,075,700.00 599,487,212.6 2-166,120,418.7 6 610,936,877.19 1,817,620,208.57 - - - - - - - 7 12008

() ()(1997)58 () () (1997)170 1997 5 6 4,230 470 14,700 1100001510319(1-1) 1999 10 2 10 3 [1999]44 1999 1,465 2000 10 3 [2001]54 2001 3,359.40 2001 2001 10 3 44,107.57 2006 3 28 (2006 4 4 ) 10 3.2 59,477,184 [2008]413 2008 4 29 35,337,590 476,413,290 2008 12 31 2008 12 31 % 253,290,162.00 53.17 223,123,128.00 46.83 476,413,290.00 100.00 () 2006 2 38 ( ) () 2008 12 31 2008 () 1 1 1 12 31 2 3 7 12008

7 12008 4 5 (1) (2) 6 (1) A B (2) (.7)

7 12008 (3) (4) (5) () (6) () ()

(7) () 7 1000 1000 % 1 1% 1 2 10% 2 3 30% 3 4 50% 4 5 80% 5 100% 8 (1) (2) 7 12008

(3) (4) 9 (1) (2) 2007 1 1 10 11 (1) (2) 7 12008

% % 20-30 3 3.23-4.85 7-14 3 6.93-13.86 8 3 12.13 5 3 19.40 (3) (4) A B 12 13 14 7 12008

15 (1) A B C (2) 3 16 17 7 12008

18 A B C 19 (1) (2) (3) 20 (1) (2) (3) (4) 21 22 1 23 7 12008

7 12008 A B A B 24 (1) () (2) 25 26 (1)

2008 1 (2) A 6% B =* = 0.8% C (120 -) () 1 2 () 1 % 61317 35 57 1525 () 25% () 15% () 15% () 25% () 15% () 25% () 15% () 25% () 25% () 25% () 25% () 25% 2 (1)(2008172 ) (2008362 ) GR200811000377 3 7 12008

(2)(2008172 ) (2008362 ) GR200811001205 3 (3)(2008172 ) (2008362 ) GR200811001271 3 (4)(2008172 ) (2008362 ) GR200834000126 3 (5)(2008172 ) (2008362 ) GR200861000203 3 2007 3 16 ( ) 2008 1 1 () 1 2008 12 31 (1) % () () 3,000.00 2.00 90.00-90.00 % (2) % () () % 5,932.68 7,753.04 100.00-100.00 5,622.92 6,681.18 100.00-100.00 8,386.26 17,237.10 100.00-100.00 1,777.78 2,104.40 100.00-100.00 8,260.87 9,705.54 100.00-100.00 12,470.82 12,377.01 100.00-100.00 5,542.16 5,200.00 93.83-93.83 8,222.19 4,700.00 56.68-56.68 4,419.10 4,000.00 90.52-90.52 7,672.59 4,000.00 52.13-52.13 () 1,500.00 500.00 33.33 66.67 100.00 80.00 60.00 75.00-75.00 () 150.00 45.00 30.00 70.00 100.00 7 12008

2 90% 2008 6 1 43.50%46.50% 2008 6 1 1 2008 10 31 52.13% 2008 1 2008 10 2008 2 () 1 2008.12.31 2007.12.31 3,918,731.51 1,108,344.57 966,648,359.53 549,203,371.19 57,864,173.69 103,976,337.64 1,028,431,264.73 654,288,053.40 2008.12.31 2007.12.31 16,055.31 6.8346 109,731.62 98.62 7.3046 720.38 - - 7.74 10.6669 82.56 109,731.62 802.94 2008 12 31 1,028,431,264.73 54,225,482.12-2008 12 31 974,205,782.61 2007 12 31 550,311,715.76 423,894,066.85 2008 12 31 54,225,482.12 2 2008.12.31 2007.12.31 173,274,488.96 251,624,538.47 78,350,049.51 31.14% 7 12008

3 (1) A (1000 ) 2008.12.31 2007.12.31 % % 34,530,345.94 4.99 471,348.46 39,477,480.78 5.90 434,941.09 - - - - - - 656,945,221.06 95.01 155,598,006.85 629,415,961.84 94.10 168,783,270.85 691,475,567.00 100.00 156,069,355.31 668,893,442.62 100.00 169,218,211.94 B 2008.12.31 2007.12.31 % % % % 1 508,306,785.95 73.51 5,908,932.68 1.16 472,396,962.65 70.62 9,836,621.44 2.08 1 2 25,483,537.88 3.69 6,732,933.97 26.42 25,531,642.02 3.82 8,892,805.85 34.83 2 3 16,542,900.49 2.39 10,496,960.74 63.45 24,567,610.09 3.67 22,342,508.48 90.94 3 4 24,485,054.54 3.54 19,863,630.01 81.13 33,054,146.32 4.94 21,700,966.79 65.65 4 5 24,522,972.28 3.55 20,932,582.05 85.36 35,775,926.03 5.35 28,878,153.87 80.72 5 92,134,315.86 13.32 92,134,315.86 100.00 77,567,155.51 11.60 77,567,155.51 100.00 691,475,567.00 100.00 156,069,355.31 668,893,442.62 100.00 169,218,211.94 C 2008.01.01 2008.12.31 169,218,211.94 6,382,054.96-19,530,911.59 156,069,355.31 7,526,806.24 12,004,105.35 D 2008 12 31 133,711,241.58 19,479,842.56 E 2008 12 31 5%( 5%) F 2008 12 31 66,063,613.25 9.55% 2 G 2008 12 31 49,849,997.36 7 12008

(2) A 2008.12.31 2007.12.31 % % (1000 ) 94,128,832.48 93.60-73,982,158.96 82.63 - - - - - - - 6,435,988.28 6.40 2,076,091.16 15,548,896.39 17.37 4,442,662.97 100,564,820.76 100.00 2,076,091.16 89,531,055.35 100.00 4,442,662.97 B 2008.12.31 2007.12.31 % % % % 1 97,522,636.07 96.97 4,045.41-79,472,197.57 88.78 91,717.06 0.12 1 2 38,992.25 0.04 3,899.23 10.00 1,695,108.66 1.89 169,510.87 10.00 2 3 947,473.35 0.94 284,242.00 30.00 2,054,593.12 2.29 616,377.94 30.00 3 4 71,243.09 0.07 35,621.55 50.00 5,462,397.80 6.10 2,731,198.90 50.00 4 5 1,227,517.80 1.22 991,324.77 80.76 64,500.00 0.07 51,600.00 80.00 5 756,958.20 0.76 756,958.20 100.00 782,258.20 0.87 782,258.20 100.00 100,564,820.76 100.00 2,076,091.16 89,531,055.35 100.00 4,442,662.97 C 2008.01.01 2008.12.31 4,442,662.97-2,366,571.81-2,076,091.16 4 (1) 2008.12.31 2007.12.31 % % 1 157,284,697.48 71.10 119,010,790.52 81.78 1 2 52,414,483.42 23.70 14,910,080.59 10.25 2 3 4,370,125.57 1.98 9,667,445.96 6.64 3 7,130,207.86 3.22 1,943,690.72 1.33 221,199,514.33 100.00 145,532,007.79 100.00 7 12008

A 75,667,506.54 51.99% B 1 C 2008 12 31 5%( 5%) 5 2008.12.31 2007.12.31 1,113,288.33-6 (1) A (1000) 2008.12.31 2007.12.31 % % 89,195,260.73 43.45 89,195,260.73 251,826,460.73 70.22 90,821,572.73 - - - - - - 116,104,123.50 56.55 34,910,031.66 106,812,008.96 29.78 36,852,387.99 205,299,384.23 100.00 124,105,292.39 358,638,469.69 100.00 127,673,960.72 B 2008.12.31 2007.12.31 % % % % 1 54,919,322.47 26.75 1,863,566.70 3.39 215,759,270.66 60.16 9,497,606.58 4.40 1 2 40,238,805.65 19.60 12,754,327.31 31.70 26,953,631.15 7.52 20,041,398.79 74.36 2 3 15,353,625.45 7.48 15,268,299.17 99.44 52,366,261.68 14.60 50,506,626.74 96.45 3 4 47,845,242.05 23.31 47,489,125.76 99.26 40,906,141.69 11.41 26,161,198.37 63.95 4 5 31,026,719.35 15.11 30,814,304.19 99.32 5,965,976.20 1.66 4,779,941.93 80.12 5 15,915,669.26 7.75 15,915,669.26 100.00 16,687,188.31 4.65 16,687,188.31 100.00 205,299,384.23 100.00 124,105,292.3 9 358,638,469.69 100.00 127,673,960.7 2 7 12008

C 2008.01.01 2008.12.31 127,673,960.72 3,924,387.69-7,493,056.02 124,105,292.39 a 2008 12 31 112,526,698.20 50,266,465.19 b 20,884.51 7,472,171.51 D 149,770,417.13 64.85% 162,631,200.00 E 2008 12 31 5%( 5%) F 2008 12 31 22,694,899.38 11.05 % 2-3 (2) A 2008.12.31 2007.12.31 % % (1000) 681,216,085.62 95.24 89,195,260.73 880,088,909.66 96.79 98,693,004.41 - - - - - - 34,019,578.30 4.76 8,480,000.53 29,169,507.55 3.21 15,757,932.94 715,235,663.92 100.00 97,675,261.26 909,258,417.21 100.00 114,450,937.35 B 2008.12.31 2007.12.31 % % % % 1 363,840,411.47 50.87 554,147.96 0.15 606,598,943.33 66.71 1,683,525.39 0.28 1 2 71,892,010.09 10.05 278,655.99 0.39 133,920,770.25 14.73 19,512,365.97 14.57 2 3 118,212,076.42 16.53 5,128,737.63 4.34 123,027,473.75 13.53 54,417,412.70 44.23 3 4 116,512,205.80 16.29 53,419,491.23 45.85 41,244,779.55 4.54 34,380,009.83 83.36 4 5 40,337,563.79 5.64 33,852,832.10 83.92 4,213,029.18 0.46 4,204,202.31 99.79 5 4,441,396.35 0.62 4,441,396.35 100.00 253,421.15 0.03 253,421.15 100.00 715,235,663.92 100.00 97,675,261.26 909,258,417.21 100.00 114,450,937.35 7 12008

C 2008.01.01 2008.12.31 114,450,937.35-16,775,676.09-97,675,261.26 7 (1) 2008.01.01 2008.12.31 61,836,769.78 759,284,930.17 715,290,640.67 105,831,059.28 47,370,570.28 672,272,737.15 680,313,770.32 39,329,537.11 1,077,200.41 13,011,764.38 10,875,929.80 3,213,034.99 7,882,945.35 201,571,003.15 189,281,653.63 20,172,294.87 417,694,633.41 3,393,952,369.03 3,385,176,247.27 426,470,755.17-76,732,135.96 76,192,189.83 539,946.13-24,984,540.32 24,984,540.32-12,585,266.86 236,640,894.91 223,060,004.82 26,166,156.95 548,447,386.09 5,378,450,375.07 5,305,174,976.66 621,722,784.50 (2) 2008.01.01 2008.12.31 959,175.06 6,625,586.73-2,852,307.74 4,732,454.05-1,973,190.41 - - 1,973,190.41 72,606.70 - - - 72,606.70 88,931.09 - - - 88,931.09 18,762,534.68 6,083,378.87-14,527,509.09 10,318,404.46 19,883,247.53 14,682,156.01-17,379,816.83 17,185,586.71 A B 14,804,555.92 6,111,307.57 C 3,750,944.71 13,628,872.12 8 2008.12.31 2007.12.31 37,303,317.92-9 (1) 2008.01.01 2008.12.31 - - - - 38,777,844.37 1,404,586.48 2,938,490.72 37,243,940.13 155,495,804.82 50,000.00 500,000.00 155,045,804.82 194,273,649.19 1,454,586.48 3,438,490.72 192,289,744.95-111,338,623.95 - -500,000.00-110,838,623.95 82,935,025.24 1,454,586.48 2,938,490.72 81,451,121.00 7 12008

A % % 38.94 38.94 103,534,361.84 1,103,300,913.44 2,821,134.44 49.00 49.00 10,025,684.89 4,490,567.41 34,586.59 B % % 30.00 30.00 66.61 66.61 81.16 81.16 65.00 65.00 1.03 1.03 7.01 7.01 2.00 2.00 20.00 20.00 6.41 6.41 60.00 60.00 10.00 10.00 0.00017 0.00017 C 2008.01.01 2008.12.31 65,223.95 65,223.95 - - 65,223.95 40,000,000.00 40,000,000.00 - - 40,000,000.00 50,000,000.00 50,000,000.00 - - 50,000,000.00 8,775,000.00 8,775,000.00 - - 8,775,000.00 5,065,000.00 5,065,000.00 - - 5,065,000.00 20,000,000.00 20,000,000.00 - - 20,000,000.00 20,000,000.00 20,000,000.00 - - 20,000,000.00 7,998,000.00 7,998,000.00 - - 7,998,000.00 500,000.00 500,000.00-500,000.00-600,000.00 600,000.00 - - 600,000.00 2,492,580.87 2,492,580.87 - - 2,492,580.87 50,000.00-50,000.00-50,000.00 155,495,804.82 50,000.00 500,000.00 155,045,804.82 7 12008

D 2008.01.01 2008.12.31 40,000,000.00 31,224,081.81-1,098,549.75 - - 32,322,631.56 4,900,000.00 4,893,924.14-27,384.43 - - 4,921,308.57 1,609,400.00 2,659,838.42 278,652.30 2,246,853.33 691,637.39-38,777,844.37-1,404,586.48 2,246,853.33 691,637.39 37,243,940.13 E 2008.01.01 2008.12.31 600,000.00 - - 600,000.00 5,000,000.00 - - 5,000,000.00 65,223.95 - - 65,223.95 40,000,000.00 - - 40,000,000.00 50,000,000.00 - - 50,000,000.00 8,775,000.00 - - 8,775,000.00 6,398,400.00 - - 6,398,400.00 500,000.00-500,000.00-111,338,623.95-500,000.00 110,838,623.95 500,000.00 (2) 2008.01.01 2008.12.31 558,929,520.00 179,253,252.13 40,000,000.00 698,182,772.13 - - - - 41,498,288.08 1,878,139.91-43,376,427.99 152,403,223.95-500,000.00 151,903,223.95 752,831,032.03 181,131,392.04 40,500,000.00 893,462,424.07-290,069,411.62-8,811,946.64-40,500,000.00-258,381,358.26 462,761,620.41 172,319,445.40-635,081,065.81 A 228,259,792.41 1,192,217,908.30 22,914,718.20 96,623,532.49 40,708,843.77 406,801.94 162,052,091.71 200,507,910.75 11,926,313.09 37,324,220.38 57,068,370.46-112,872.75 344,335,970.12 617,529,113.79 94,480,279.49 50,414,111.01 292,455,900.33-4,544,048.44 37,274,800.64 177,077,850.15 9,661,530.10 153,930,176.20 2,260,706,538.70 23,495,468.18-253,058.13 84,867,744.27-622,777.24-2,614,483.02 85,908,235.13 175,066.04-21,177,817.45 8,305,475.07-12,916,714.20 7 12008

B % % 33.33 33.33 18,103,140.09 62,530,496.71 2,484,223.90 30.00 30.00 354,703.53 15,103,937.09-252,620.33 38.94 38.94 103,534,361.84 1,103,300,913.44 2,821,134.44 49.00 49.00 10,025,684.89 4,490,567.41 34,586.59 C % % 30.00 30.00 66.61 66.61 81.16 81.16 65.00 65.00 1.03 1.03 7.01 7.01 2.00 2.00 20.00 20.00 6.41 6.41 D 2008.01.01 2008.12.31 77,530,444.56 52,479,300.00 25,051,144.56-77,530,444.56 66,811,811.58 47,794,800.00 19,017,011.58-66,811,811.58 172,371,032.22 50,000,000.00 122,371,032.22-172,371,032.22 21,043,992.40 16,000,020.00 5,043,972.40-21,043,992.40 97,055,400.00 97,055,400.00 - - 97,055,400.00 123,770,089.37 116,000,000.00 7,770,089.37-123,770,089.37 52,000,000.00 52,000,000.00 - - 52,000,000.00 47,000,000.00 47,000,000.00 - - 47,000,000.00 40,000,000.00 40,000,000.00 - - 40,000,000.00 40,000,000.00 40,000,000.00-40,000,000.00-600,000.00 600,000.00 - - 600,000.00 2.00-2.00-2.00 65,223.95 65,223.95 - - 65,223.95 40,000,000.00 40,000,000.00 - - 40,000,000.00 50,000,000.00 50,000,000.00 - - 50,000,000.00 8,775,000.00 8,775,000.00 - - 8,775,000.00 5,065,000.00 5,065,000.00 - - 5,065,000.00 20,000,000.00 20,000,000.00 - - 20,000,000.00 20,000,000.00 20,000,000.00 - - 20,000,000.00 7,998,000.00 7,998,000.00 - - 7,998,000.00 500,000.00 500,000.00-500,000.00-711,332,743.95 179,253,252.13 40,500,000.00 850,085,996.08 7 12008

E 2008.01.01 2008.12.31 5,000,000.00 5,198,084.97-827,991.83 - - 6,026,076.80 40,000,000.00 31,224,081.81-1,098,549.75 - - 32,322,631.56 4,900,000.00 4,893,924.14-27,384.43 - - 4,921,308.57 450,000.00 182,197.16 - -75,786.10 - - 106,411.06 41,498,288.08-1,878,139.91 - - 43,376,427.99 F 2008.01.01 2008.12.31 64,878,701.45 8,477,276.91-73,355,978.36 34,186,755.95 - - 34,186,755.95 39,665,330.27 334,669.73-40,000,000.00 600,000.00 - - 600,000.00 40,000,000.00-40,000,000.00-5,000,000.00 - - 5,000,000.00 65,223.95 - - 65,223.95 40,000,000.00 - - 40,000,000.00 50,000,000.00 - - 50,000,000.00 8,775,000.00 - - 8,775,000.00 6,398,400.00 - - 6,398,400.00 500,000.00-500,000.00-290,069,411.62 8,811,946.64 40,500,000.00 258,381,358.26 10 2008.01.01 2008.12.31 115,728,084.67 - - 115,728,084.67 1 115,728,084.67 - - 115,728,084.67 2 - - - - 13,257,568.00 4,671,360.21-17,928,928.21 1 13,257,568.00 4,671,360.21-17,928,928.21 2 - - - - - - - - 1 - - - - 2 - - - - 102,470,516.67 97,799,156.46 1 102,470,516.67 97,799,156.46 2 - - 7 12008

11 (1) 2008.01.01 2008.12.31 691,133,504.51 187,388,173.31 49,906,059.21 828,615,618.61 662,691,293.04 163,110,645.04 46,298,451.42 779,503,486.66 53,659,910.20 11,082,766.78 9,935,337.41 54,807,339.57 32,833,258.84 8,354,128.92 5,741,255.29 35,446,132.47 1,440,317,966.59 369,935,714.05 111,881,103.33 1,698,372,577.31 A 93,316,555.48 B 2008 12 31 203,689,496.35 171,350,069.73 (2) 2008.01.01 2008.12.31 125,836,005.69 51,907,670.33 20,119,924.71 157,623,751.31 285,909,008.49 91,535,448.78 22,466,291.78 354,978,165.49 26,842,845.58 7,762,636.98 7,893,935.93 26,711,546.63 21,980,718.40 8,538,292.45 5,206,860.18 25,312,150.67 460,568,578.16 159,744,048.54 55,687,012.60 564,625,614.10 (3) 2008.01.01 2008.12.31 11,820,187.30 13,049.61-11,833,236.91 14,319,418.61 14,357,068.55 3,193,199.11 25,483,288.05 10,007.14 271,633.10 10,007.14 271,633.10 86,888.65-78,917.37 7,971.28 26,236,501.70 14,641,751.26 3,282,123.62 37,596,129.34 A 128,587,069.12 56,254,689.77 6,482,857.24 B 3,203,206.25 36,477,028.54 18,361,793.20 78,917.37 (4) 2008.01.01 2008.12.31 553,477,311.52 659,158,630.39 362,462,865.94 399,042,033.12 26,807,057.48 27,824,159.84 10,765,651.79 10,126,010.52 953,512,886.73 1,096,150,833.87 7 12008

12 (1) % 39,950,000.00 90.00% () 81,910,000.00 30.00% (E ) 15,000,000.00 100.00% (K ) 30,560,000.00 70.00% 2008 6,540,000.00 90.00% 2008 ( 2007) 27,020,000.00 50.00% 2008 / 4,360,000.00 90.00% M 10,570,000.00 100.00% ( 2007 ) 33,810,000.00 100.00% - - 100.00% - 100.00% 2007 (/ )--- 19,680,000.00 100.00% 2007 (/ )-- 19,540,000.00 20.00% -- 2007 28,190,000.00 90.00% -- 2007 40,370,000.00 80.00% 2,770,000.00 100.00% 7,580,000.00 88.00% 2,700,000.00 74.00% 1,720,000.00 70.00% 08 35,000,000.00 11.00% + 220,000.00 100.00% 500,000.00 65.20% 2,452,400.00 70.00% CGMP 63,030,000.00 45.00% GMP 5,685,600.00 100.00% 2007 29,580,000.00 48.60% 2008 2,520,000.00 0.00% 2006 38,580,300.00 100.00% 2007 124,030,000.00 0.00% 2008 28,680,000.00 63.00% 77,060,000.00 100.00% 32,028,000.00 7 12008

(2) 2008.01.01 2008.12.31 10,657,289.20 13,135,906.52 21,972,826.71-1,820,369.01 - () - 8,098,444.12 - - 8,098,444.12 - (E ) - 6,535,589.00 6,535,589.00 - - - (K) - 20,139,978.31 - - 20,139,978.31-2008 - 1,985,466.00 - - 1,985,466.00-2008 ( 2007-8,139,873.04 - - 8,139,873.04 - ) 2008 / - 1,448,959.90 - - 1,448,959.90 - M 86,548.00 39,937.00 126,485.00 - - - ( 2007 ) 1,403,134.61 5,228,890.03 6,200,912.44 431,112.20 - - - 1,888,719.58 1,761,197.77 3,649,917.35 - - - 10,113.14 43,969.32 54,082.46 - - - 2007 (/ )- 2007 (/ )-- -- 2007 -- 2007 1,186,724.42 2,671,489.20 3,858,213.62 - - - - 4,935,638.32 - - 4,935,638.32-4,002,650.45 14,509,504.66 - - 18,512,155.11 - - 2,448,235.67 - - 2,448,235.67 - - 159,031.40 159,031.40 - - - 3,327,939.50 1,675,668.50 - - 5,003,608.00 - - 1,507,171.20 - - 1,507,171.20 - - 1,353,000.00 - - 1,353,000.00-08 + - 2,525.00 - - 2,525.00 - - 297,039.00 297,039.00 - - - 7 12008

- 198,000.00 - - 198,000.00 - - 344,578.00 - - 344,578.00 - CGMP - 13,052,981.66 - - 13,052,981.66 - GMP - 4,917,750.00 4,917,750.00 - - - 2007 2008 2006 ( ) 2007 2008-10,228,652.66 - - 10,228,652.66 - - - - - - - 18,009,827.85 16,764,567.68 34,774,395.53 - - - 130,000.00 112,808.26 - - 242,808.26 - - 10,535,342.48 - - 10,535,342.48 387,860.00-7,423,611.77 7,423,611.77 - - - 3,170,203.68 8,663,627.33 3,346,701.20 171,967.46 8,315,162.35-43,873,150.43 168,359,433.80 93,316,555.48 603,079.66 118,312,949.09 387,860.00 A 74,439,798.66 169.67% B (3) 13 2008.12.31 2007.12.31 1,055,500.18 40,000.00 8,415,295.13 347,700.00 9,470,795.31 387,700.00 9,083,095.31 2342.82% 14 (1) 2008.01.01 2008.12.31 15,000,000.00 - - 15,000,000.00 12,000,000.00 - - 12,000,000.00 8,000,000.00 - - 8,000,000.00 8,000,000.00 - - 8,000,000.00 10,000,000.00 - - 10,000,000.00 7,000,000.00 - - 7,000,000.00 7 12008

2,200,000.00 - - 2,200,000.00 HBV 400,000.00 - - 400,000.00 100,000.00 - - 100,000.00 8,000,000.00 - - 8,000,000.00 130/0.4 4,000,000.00 - - 4,000,000.00 2,800,000.00 - - 2,800,000.00 3,000,000.00 - - 3,000,000.00 3,800,000.00 260,000.00-4,060,000.00 800,000.00 - - 800,000.00 14,110,000.00 138,000.00-14,248,000.00 92,370.00-92,370.00-3,729,000.00 - - 3,729,000.00 10,700,000.00 140,000.00-10,840,000.00 121,603,519.24 7,500,000.00 10,405,662.63 118,697,856.61 8,863,776.75 996,132.37 9,722.22 9,850,186.90-3,515,708.53-3,515,708.53-2,085,333.00-2,085,333.00-2,626,471.87-2,626,471.87 244,198,665.99 17,261,645.77 10,507,754.85 250,952,556.91 A 3,515,708.53 2,626,471.87 B 2,085,333.00 (2) 2008.01.01 2008.12.31 14,000,000.00 1,000,000.00-15,000,000.00 5,288,695.84 - - 5,288,695.84 2,489,086.45 - - 2,489,086.45 2,489,077.80 - - 2,489,077.80 4,579,432.20 287,233.48-4,866,665.68 6,416,630.67 583,369.33-7,000,000.00 1,539,999.55 220,001.12-1,760,000.67 HBV 239,999.35 - - 239,999.35 70,000.12 10,000.08-80,000.20 6,400,000.24 1,599,999.76-8,000,000.00 130/0.4 1,333,333.41 800,000.00-2,133,333.41 1,400,000.00 560,000.08-1,960,000.08 925,000.00 300,000.00-1,225,000.00 411,666.67 395,439.42-807,106.09 373,333.52 80,000.04-453,333.56 7 12008

6,486,628.19 2,663,505.12-9,150,133.31 5,433.53 17,658.97 23,092.50-2,548,150.00 372,900.00-2,921,050.00 5,356,250.04 1,631,999.61-6,988,249.65 11,913,838.64 5,313,276.27-17,227,114.91 4,043,138.32 1,162,667.84-5,205,806.16-501,911.40-501,911.40-316,583.04-316,583.04-393,970.78-393,970.78 78,309,694.54 18,210,516.34 23,092.50 96,497,118.38 (3) 2008.01.01 2008.12.31 6,711,304.16 - - 6,711,304.16 5,133,334.32 - - 5,133,334.32 5,510,922.20 - - 5,510,922.20 5,510,913.55 - - 5,510,913.55 HBV 160,000.65 - - 160,000.65 23,026,474.88 - - 23,026,474.88 (4) 2008.01.01 2008.12.31 1,000,000.00 - - - - - - - - - - - 287,233.48 - - 583,369.33 - - 660,000.45 439,999.33 2.00 HBV - - 2.00 29,999.88 19,999.80 2.00 1,599,999.76 - - (13 ) 2,666,666.59 1,866,666.59 2.33 1,400,000.00 839,999.92 1.50 2,075,000.00 1,775,000.00 5.92 3,388,333.33 3,252,893.91 7.92 426,666.48 346,666.44 4.33 7,623,371.81 5,097,866.69 1~7 86,936.47 - - 1,180,850.00 807,950.00 2.17 5,343,749.96 3,851,750.35 0.42~9.92 7 12008

109,689,680.60 101,470,741.70 1.75~48 4,820,638.43 4,644,380.74 0.25~9.58-3,013,797.13 4.33-1,768,749.96 4.50-2,232,501.09 4.25 142,862,496.57 131,428,963.65 15 2008.01.01 2008.12.31-35,541,499.42 35,541,499.42-35,541,499.42-20,758,496.63 11,674,305.01 16,078,152.31 16,354,649.33 9,935,971.91 6,142,180.40 20,758,496.63 47,215,804.43 51,619,651.73 16,354,649.33 45,477,471.33 6,142,180.40 4,403,847.30 32.73% 16 2008.01.01 2008.12.31 701,404.37 701,404.37-701,404.37 701,404.37 812,728.98 812,728.98-812,728.98-2008 6 8,261,105.25-8,261,105.25 8,261,105.25-9,775,238.60 1,514,133.35 8,261,105.25 9,775,238.60 701,404.37 116,000,000.00 115,298,595.63 701,404.37 47,000,000.00 46,187,271.02 812,728.98 2.00-8,261,103.25 8,261,105.25 9,775,238.60 17 2008.01.01 2008.12.31 () 8,431,547.65 371,792.01 428,538.64 311,586.94 7,942,803.94 488,743.71 0.75~2.5 502,000.00 107,060.74 28,078.54 423,017.80 78,982.20 4.00 665,083.00-665,083.00 1,626.12 1,626.12 663,456.88 34.00 2,082,903.00 434,404.60 431,112.20 182,992.63 1,400,378.83 682,524.17 0.17~4.83 11,681,533.65 913,257.35 1,524,733.84 524,284.23 9,767,826.69 1,913,706.96 7 12008

18 2008.12.31 2007.12.31 11,246,714.36 53,795,174.04 9,567,136.39 56,314,159.34 2,392,831.17 9,887,383.00 204,268.75 1,361,791.67 4,938,311.96 25,205,885.20 2,039,052.45 11,354,070.30 12,000.00 80,000.00 419,914.98 2,799,433.20 3,192,530.48 14,686,941.63 - - 2,823,782.81 12,235,714.67 2,058,266.34 13,720,967.86 24,606,170.78 115,891,098.54 14,288,638.91 85,550,422.37 19 2008.01.01 2008.12.31 296,892,172.66 10,410,292.60-27,127,817.56 280,174,647.70 19,883,247.53 14,682,156.01-17,379,816.83 17,185,586.71 111,338,623.95 - - 500,000.00 110,838,623.95 26,236,501.70 14,641,751.26-3,282,123.62 37,596,129.34 23,026,474.88 - - - 23,026,474.88 701,404.37 - - - 701,404.37 478,078,425.09 39,734,199.87-48,289,758.01 469,522,866.95 20 2008.01.01 2008.12.31 1 48,354,339.50-48,354,339.50-2 - 171,350,069.73-171,350,069.73 3-114,090,864.48 64,240,867.12 49,849,997.36 103,976,337.6-49,750,855.52 54,225,482.12 48,354,339.50 285,440,934.21 112,595,206.62 221,200,067.09 (1)11 3 (2) 21 2008.12.31 2007.12.31 170,000,000.00 170,000,000.00 84,000,000.00 30,000,000.00 71,500,000.00 104,000,000.00 325,500,000.00 304,000,000.00 (1) 2008 12 31 7 12008

(2) 400 2008 3 31 3,000 2008 6 6 1,500 2008 8 28 1,000 2008 9 28 500 2008 9 18 1,000 2008 11 14 1,000 2008 12 30 49,849,997.36 (3) 3,000 1,000 500 700 1,000 500 450 2008 9 16 2009 9 16 2008 3 21 2009 3 20 2008 3 21 2009 3 20 2008 3 21 2009 3 20 2008 3 21 2009 3 20 2008 2 21 2009 1 21 2008 2 21 2009 1 21 22 2008.12.31 2007.12.31 130,151,954.43 203,080,829.62 (1) (2) 2008 12 31 5%( 5%) 23 (1) 2008.12.31 2007.12.31 % % 1 230,120,557.26 74.14 307,275,038.67 78.82 1 2 54,894,101.56 17.69 20,371,981.79 5.22 2 3 1,830,327.86 0.59 6,295,293.45 1.61 3 23,519,211.95 7.58 55,969,867.01 14.35 310,364,198.63 100.00 389,912,180.92 100.00 (2) 2008 12 31 5%( 5%) (3) 1 7 12008

24 (1) 2008.12.31 2007.12.31 % % 1 22,824,550.56 78.02 63,081,075.59 91.64 1 2 1,775,072.21 6.07 2,134,591.23 3.10 2 3 1,033,253.98 3.53 289,278.90 0.42 3 3,622,818.45 12.38 3,333,539.55 4.84 29,255,695.20 100.00 68,838,485.27 100.00 (2) 2008 12 31 5%( 5%) 25 2008.01.01 2008.12.31 5,391,783.51 326,380,297.96 320,741,981.35 11,030,100.12-24,618,042.82 24,618,042.82-1,107,834.15 91,963,385.47 86,834,551.93 6,236,667.69 (1) 144,244.37 21,545,954.27 19,238,353.72 2,451,844.92 (2) 853,112.16 49,929,827.51 47,977,923.84 2,805,015.83 (3) - 13,478,318.00 13,478,318.00 - (4) 30,233.53 4,130,492.43 3,859,554.25 301,171.71 (5) 31,774.07 1,411,063.75 1,210,235.09 232,602.73 (6) 48,470.02 1,467,729.51 1,070,167.03 446,032.50 342,669.00 32,406,392.66 31,174,502.22 1,574,559.44 14,099,621.84 10,825,339.18 10,190,212.50 14,734,748.52 - - - - - 1,549,370.44 1,549,370.44-1,347,994.40 1,379,093.62 1,431,121.48 1,295,966.54 - - - - 22,289,902.90 489,121,922.15 476,539,782.74 34,872,042.31 26 2008.12.31 2007.12.31 47,178,928.57 48,099,336.29 1,919,659.34 19,739,390.56 2,740,526.53 3,141,690.48 3,280,156.88 42,275,271.49 1,478,333.75 2,442,036.39 809,133.55 1,394,345.17 482,878.60 375,406.59-6,120.00-10,778.24 39,012.12 2,979,167.41 2,804,516.39 60,873,442.87 120,311,005.48 7 12008

27 (1) 2008.12.31 2007.12.31 % % 1 87,043,603.01 51.11 42,272,736.09 30.04 1 2 41,508,371.71 24.38 18,167,011.35 12.91 2 3 18,009,557.84 10.58 27,616,063.72 19.63 3 23,724,708.49 13.93 52,661,469.78 37.42 170,286,241.05 100.00 140,717,280.94 100.00 (2) 5%( 5%) 14,953,632.73 28 2008.12.31 2007.12.31 16,000,000.00 7,000,000.00 2008.12.31 2006-5-31 2009-5-30 16,000,000.00 16,000,000.00 29 2008.01.01 2008.12.31 27,000,000.00 - - 27,000,000.00 30 2008.12.31 2007.12.31 2,984,580.11 11,938,320.44 - - 832,945.64 5,552,970.93 1,894,533.28 12,630,221.87 3,817,525.75 17,491,291.37 1,894,533.28 12,630,221.87 2008 1,922,992.47 101.50% 31 2008.12.31 2007.12.31 1,475,828.80 1,573,728.80 8,961,343.37 5,696,593.37 10,437,172.17 7,270,322.17 7 12008

32() 2008.01.01 2008.12.31 % % 1 - - - - - - - - - 2 19,514.91 44.24 1,800.88 - - 2,280.35 4,081.23 23,596.14 49.53 3 58.33 0.13 1,732.88 - - -58.33 1,674.55 1,732.88 3.64 58.33 0.13 1,732.88 - - -58.33 1,674.55 1,732.88 3.64 - - - - - - - - - 4 - - - - - - - - - - - - - - - - - - - - - - - - - - - 19,573.23 44.37 3,533.76 - - 2,222.03 5,755.78 25,329.02 53.17 1 24,534.34 55.62 - - - -2,222.03-2,222.03 22,312.31 46.83 2 - - - - - - - - - 3 - - - - - - - - - 4 - - - - - - - - - 24,534.34 55.62 - - - -2,222.03-2,222.03 22,312.31 46.83 44,107.57 100.00 3,533.76 - - - 3,533.76 47,641.33 100.00 2008 4 3533.76 2008 4 25 (2008) 029 33 2008.01.01 2008.12.31 567,123,115.00 620,423,920.17 66,960,704.52 1,120,586,330.65 42,319,549.30 835,018.00-43,154,567.30 609,442,664.30 621,258,938.17 66,960,704.52 1,163,740,897.95 (1) (2) 824,581.00 10,437.00 7 12008

34 2008.01.01 2008.12.31 166,120,418.76 23,823,840.51-189,944,259.27 35 2008 2007 980,834,215.56 526,986,635.89-122,405,370.71 980,834,215.56 649,392,006.60 - - 380,572,486.34 437,580,763.41 23,823,840.51 35,566,444.57 - - 88,136,460.82 70,572,109.88 - - 1,249,446,400.57 980,834,215.56 14,605,652.17 8,231,352.27 (1) 2008 10% (2)2008 3 36 2008.12.31 2007.12.31-23,696,839.31-14,392,834.59-60,620,789.40 595,380.42 4,381,225.34 1,340,648.09 2,117,496.48-3,836,079.53 2,299,855.23 1,703,738.81 66,682,552.33 56,430,671.51-35,049.37 70,918,436.07 167,214,724.34 7 12008

37 (1) A 2008 2007 4,907,335,994.97 4,491,477,548.59 44,188,372.85 65,138,832.53 4,951,524,367.82 4,556,616,381.12 B 2008 2007 4,852,434,249.39 3,342,639,192.87 4,453,133,355.59 3,117,151,736.25 54,901,745.58 41,414,353.15 38,344,193.00 27,182,192.32 4,907,335,994.97 3,384,053,546.02 4,491,477,548.59 3,144,333,928.57 C 247,560,274.83 5% (2) A 2008 2007 740,029,848.26 654,772,640.84 22,950,316.41 42,305,166.13 762,980,164.67 697,077,806.97 B 2008 2007 740,029,848.26 297,674,894.95 654,772,640.84 236,014,846.70 C 717,174,830.95 94.00% 7 12008

38 2008 2007 3%5% 2,512,452.92 1,960,685.49 5%7% 18,944,995.47 16,759,020.56 3%4% 9,453,364.38 7,945,529.17 1,555,710.47 1,429,410.77 32,466,523.24 28,094,645.99 39 2008 2007 10,306,442.65 29,132,661.09 8,570,848.44 5,522,226.69-1,175,000.00 8,158,894.02 16,172,247.96 27,036,185.11 52,002,135.74 40 (1) A 2008 2007 1,113,288.33-1,098,549.75 415,455.09 16,947.43-670,132.95 278,652.30 557,353.63-1,560.00 26,968,950.84-500,000.00 - - 1.00 29,976,388.65 304,236.77 B 2008 2007 2,507,437.81 304,235.77 1,394,149.48 302,675.77 1,113,288.33 1,560.00 27,468,950.84 1.00 29,976,388.65 304,236.77 29,672,151.88 9752.98% 7 12008

(2) A 2008 2007 1,113,288.33-827,991.83 159,357.14 1,098,549.75 415,455.09 16,947.43-670,132.95-75,786.10 182,197.16 1.00-500,000.00 - - 1.00 3,480,992.24 86,877.44 B 2008 2007 2,980,991.24 86,876.44 1,867,702.91 86,876.44 1,113,288.33-500,001.00 1.00 3,480,992.24 86,877.44 41 2008 2007 16,651,844.59 196,907,661.33 22,844,653.40 11,406,704.00-764,000.00 1,663,280.63 3,495,547.90 41,159,778.62 212,573,913.23 171,414,134.61 80.64% 7 12008

42 (1) 2008 2007-500,000.00 500,000.00-08 780,000.00 - - 2008-- 2,500,000.00-3,780,000.00 500,000.00-106,500.00 07- - 100,000.00 18,881,839.00 11,200,204.00 2,265,000.00-30,000.00-50,000.00-400,000.00-150,000.00-255,014.40-700,000.00-112,800.00-22,844,653.40 11,406,704.00 26,624,653.40 11,906,704.00 7 12008

(2) 2008 2007 2008.12.31 2007.12.31 - - 300,000.00 300,000.00, - - 280,000.00 280,000.00 - - 2,919,750.00 3,435,000.00 - - 631,593.37 631,593.37 - - 550,000.00 550,000.00 - - 500,000.00 500,000.00 - - 500,000.00-08 - - 780,000.00 - - 2008-- - - 2,500,000.00 - - - 8,961,343.37 5,696,593.37-106,500.00 - - 07- - 100,000.00 - - 18,881,839.00 11,200,204.00 - - 2,265,000.00 - - - 30,000.00 - - - 50,000.00 - - - 400,000.00 - - - 150,000.00 - - - 255,014.40 - - - 700,000.00 - - - 112,800.00 - - - 22,844,653.40 11,406,704.00 - - 22,844,653.40 11,406,704.00 8,961,343.37 5,696,593.37 7 12008

A, 2004,, 300,000.00, 2008 12 31 300,000.00 B 2002,, 2008 12 31 280,000.00 C[2003]884, 2003-2006 3,435,000.00 2008 4 1 5 515,250.00 D 2008 12 31 631,593.37 E 2008 12 31 550,000.00 F[2007]42 2006 2006, 500,000.00,- 2008 12 31, 500,000.00 G200890 500,000.00 -( ) 2008 12 31 500,000.00 H 2008 2008 780,000.00, 4000 2008 12 31 780,000.00 I-2008273 2008 () 2,500,000.00 2008 12 31 2,500,000.00 J[2003]69 5000 2008 1 18,881,839.00 2008 18,881,839.00 K 2007 20083 2,265,000.00 2008 2,265,000.00 L 2008 12 30,000.00 2008 30,000.00 7 12008

M 2008 4 50,000.00 2008 50,000.00 N 2007 2008 5 12 400,000.00 2008 400,000.00 O2008154 2008 10 150,000.00 2008 150,000.00 P 2008 12 255,014.40 2008 255,014.40 Q 700,000.00 2008 700,000.00 R 2008 8 112,800.00 2008 112,800.00 43 2008 2007 407,352.87 1,299,226.54 39,385.14-7,334,354.91-345,093.29 255,299.46-27,000,000.00 9,321,132.16-5,088,257.75 3,099,915.62 22,535,576.12 31,654,441.62 2008 12 19 2003 710 9,321,132.16 44 2008 2007 82,593,878.72 112,390,315.10-8,394,539.40 4,686,870.83 74,199,339.32 117,077,185.93 7 12008

2008 2007 469,541,493.40 574,684,384.48 15% 70,431,224.01 189,645,846.88-1,494,617.72-100,939,749.87 - - -167,324.58 - -267,488.38-28,804,151.48 8,405,687.07 57,037,609.15-3,745,805.41 - -4,762,564.84-8,033,608.55 5,800,229.17 8,171,239.80 - - 74,199,339.32 117,077,185.93 45 2008 2007 a 380,572,486.34 437,580,763.41 b 464,634,093.33 441,075,700.00 a/b 0.82 0.99 46 76,484,715.02 2008 2007 26,733,859.50 11,906,704.00 49,750,855.52-7 12008

47 723,220,352.60 2008 2007 115,933,241.58 110,597,210.95 94,331,066.45 91,993,124.19 94,814,005.16 91,993,124.19 53,338,702.43 47,094,110.43 56,391,510.15 41,027,041.12 38,096,745.33 32,135,116.74 26,616,512.44 27,224,719.18-27,034,824.90 22,565,328.61 22,737,822.27 18,692,447.45 16,956,852.20 11,778,515.62 15,275,429.56 12,930,283.12 13,795,525.74 7,587,166.53 8,570,518.61 12,878,304.18 6,380,895.28 10,280,304.30 6,016,862.87 3,880,392.36 1,571,054.73 4,792,350.80-2,180,294.02-48 14,805,820.01 2008 2007 12,781,892.87 13,004,229.82 2,023,927.14-49 19,499,785.99 2008 2007 19,499,785.99-50 3,366,432.25 2008 2007 3,366,432.25 437,719.54 7 12008

51 2008 2007 1. 396,455,442.41 238,238,405.05 457,607,198.55 355,664,445.67 27,036,185.11-8,064,151.80 52,002,135.74 31,428,292.57 108,181,384.31 37,923,449.03 92,500,488.49 36,129,708.97 18,210,516.34 7,411,974.41 13,212,605.79 7,229,108.15 524,284.23-1,507,412.63 - () -16,244,491.72-12,637,751.15-195,453,367.44-187,380,150.14 () - - - - () - - - - () 12,795,499.83 10,433,409.30 11,433,776.25 7,242,107.25 () -29,976,388.65-3,480,992.24-304,236.77-86,877.44 () -7,168,990.67-49,375.80 2,792,337.55 2,459,639.59 () -1,371,223.92-1,061,587.64 1,894,533.28 1,894,533.28 () -104,872,693.67-46,493,423.52-64,057,655.13-10,094,768.44 ( ) 40,858,469.79 133,471,557.28-107,753,053.68-474,978,870.53 ( ) -171,748,703.49-11,993,058.42-29,889,187.99-17,905,738.65 59,030,855.52 10,024,833.02-34,824.90 26,161,775.64 331,710,145.42 353,723,287.52 235,458,162.37-222,236,794.08 2. - - - - - - - - - - - - 3. 974,205,782.61 728,009,488.36 550,311,715.76 7,899,493.29 550,311,715.76 7,899,493.29 391,246,690.24 203,711,618.37 - - - - - - - - 423,894,066.85 720,109,995.07 159,065,025.52-195,812,125.08 7 12008

52 2008 2,558,552,383.88 2,449,413,570.91-56,441,586.97 4,951,524,367.82 2,502,110,796.91 2,449,413,570.91-4,951,524,367.82 56,441,586.97 - -56,441,586.97-650,958,749.54 97,604,716.56-748,563,466.10 /() 439,157,443.40 15,058,824.08-2,185,688.25 452,030,579.23 3,756,303,235.64 683,116,436.04-170,398,115.41 4,269,021,556.27 707,296,486.18 531,874,213.39-120,612,427.16 1,118,558,272.41 2007 2,228,147,685.54 2,379,457,096.55-50,988,400.97 4,556,616,381.12 2,177,159,284.57 2,379,457,096.55-4,556,616,381.12 50,988,400.97 - -50,988,400.97-558,926,498.94 101,767,749.89-660,694,248.83 /() 452,202,960.20 10,461,042.37-68,899,089.70 393,764,912.87 2,984,795,171.83 775,778,405.60-87,110,202.05 3,673,463,375.38 653,763,793.22 667,475,295.76-12,463,436.56 1,308,775,652.42 () 1 (1) A ( 49.05 49.05 232,000.00 10110522-3 2008.01.01 2008.12.31 2,320,000,000.00 - - 2,320,000,000.00 B 7 12008

(2) 63365006-2 10120880-4 10175561-3 10193963-1 71390256-5 73230553-9 72261785-4 10305581-3 73167501-X 72653957-4 74936205-4 74880547-4 21764158-9 75983883-7 10165558-3 600012064 101383055 2 (1) () 2008 2007 () () () 11,453,755.04 0.24 9,903,404.10 0.22 52,692.32 0.10 666,222.22 0.60 13,418.80 0.02 1,043,781.10 0.94 4,838,055.02 0.10 6,953,445.55 0.16 31,569,779.36 0.65 35,453,765.17 0.80 53,926,220.50 1.11 48,490,174.45 1.09 451,340.15 0.82 52,649.56 0.05 4,205,994.76 0.09 2,571,918.57 0.06 - - 2,264,408.00 2.05 - - 2,000.00 - - - 533,590.00 0.48 - - 707,775.38 0.02 106,511,255.95 108,643,134.10 () () 7 12008