臺灣藥用植物雜誌 Journal of Taiwan Medicinal Plants 第十五期 2017 3 1
臺灣藥用植物雜誌 Journal of Taiwan Medicinal Plants 2017 3 1 目 錄...1...2...6 -...8...12 -...24 / / 23 / / / (04)2473-4001 / (04)2472-4002 / http://www.tcherb.org E-mail / tcherb.org@gmail.com / (04)2473-4385 / (04)2475-7301 / / / / / / / 407 231 / (04)23160278 E-mail wenhsin.press@msa.hinet.net 5,000 3,000 3,000 3,000 1,500 1,500 1,500 本雜誌內文所載醫藥知識僅供參考, 使用前務必請教有經驗之醫師, 以免誤食誤用影響身體健康
Journal of Taiwan Medicinal Plants 總編輯的話 ( ) ( ) 1
皮膚疾患常用青草藥介紹 / / ( ) ( 60~70 ) (Compliance) 豬母乳 Portulaca oleracea Linn. (noradrenaline) (dopa) (dopamine) (betanidin) (isobetanidin) (betanin) (isobetanin) (oxalic acid) (malic acid) (citric acid) (glutamic acid) (aspartic acid) (alanine) (glucose) (fructose) (sucrose) 3 ( 3-polyunsaturated fatty acid) ( ) 1 30 20 2
Journal of Taiwan Medicinal Plants 20 ( 6 )10 ( ) 2 ( ) 1 1 2 ( ) ( ) ( ) 2 30 ( ) ( ) 3 4 5 Bacopa monnieri (L.) Wettst. 無患子 Sapindus mukorossii Gaertner 24.2 (mukurozioside) (rutin) (ascorbic acid) (flavonoid) (tannin 4 ) 1 3
2 (ph 3.0) 3 4 ( Salvia plebeia R. Br. ) ( Selaginella doederleinii Hieronyus ) 5 6 1 ( ) 2 藏紅花 Crocus sativus L. 7 韭菜 Allium tuberosum Rottler ex Spreng. 4
Journal of Taiwan Medicinal Plants (oleanolic acid) (ursolic acid) (succinic acid) (benzoic acid) (salicylic acid) (syringic acid) (astragalin) 1 100 1 破布子葉 Cordia dichotoma G. Forst. 1 2 柿子葉 Diospyros kaki Thunb (isoquercitrin) (rutin) C (carotenes) (choline) ( ( ) ) 1 2 二次洗米水 (betulinic acid) 5
民間輔助抗癌驗方訪談 / / 民間流傳抗癌處方 3 1 2 7 1 2 1.3 2 3 ( 4 ) 4 5 6 7 4 ( ) ( ) ( ) 6 ( )
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臺灣金線連研究 應用 市場現況與省思 / / 前言 Orchidaceae ( )Anoectochilus Taiwan jewel orchid ( ) (1) 86 (2) (1) ( ) 12
Journal of Taiwan Medicinal Plants - 金線連品種 ( )Anoectochilus formosanus Hayata ( )Anoectochilus koshunensis Hayata (3) 2 (1 4-6) 1 Anoectochilus chapaensis Gagnep 3 Goodyera matsumurana Schltr. 4 Ludisia discolor A. Rich. 5 Zebrina pendula Schnizl 6 Goodyera velutina Maxim. 7 Commelina spp. Anoectochilus roxburghii (Wall.) Lindl. 2 Anoectochilus formosanus Anoectochilus formosanus Anoectochilus shunensis Anoectochilus formosanus 13
( ) - (Goodyera) 金線連之土壤栽培限制因素 Fusarium oxysporum f. sp. anoectochili (7 8) (Pythium? ( ) aphnidermatum) (1) 組織培養的發展優勢 Commelina spp. 14
Journal of Taiwan Medicinal Plants ( ) 22~28 1000~1500 (cd) (BA) (NAA) BA ( ) ( vitrification) (9) 金線連與蘭菌 (Rhizotonia) ( ) - 15
( ) (Rhizotonia) R02( ) R04( ) R02 (10 11) (Mycena) kinsenosides( 85.5%) isorhamnetin-3-o- -D-rutinoside ( 226.1%) isorhamnetin-3-o- -Dglucopyranoside ( 196.0%) (12) 金線連栽培與加工 10 11 12 45 ( 7~8 ) 2~3 5 5 16
Journal of Taiwan Medicinal Plants ( ) 10 ( ) 50 60 70 120 (Maillard reaction) ( ) ( ) ( 8~10 ) 17 臺灣金線連成分 Anoectochilus formosanus (kinsenoside) (Gastrodin) (type-ii Arabinogalactan 29 kda) (13-16) 現代藥理研究 7 28 0.5 g/kg 2.0 g/kg 2.0 g/kg/ day 10 g/kg 90 0.5g/kg (17-19) 5,000 mg/kg
7 14 (20) l.0 2.0 g/ kg (21) (22) (23) (24) (25 26) dimethylnitrosamine (27) (28) (29) thioacetamide BABL/c (30) (31) aurothioglucose (32) aurothioglucose (33) streptozotocin (34) (LDL) (35) 66 450 mg/day 6 12 (36) (AFEF) 18
Journal of Taiwan Medicinal Plants streptozotocin AFEF STZ AFEF AFEF AFEF (37) (38) 6 Spraque-Dawley 11 (39) (40) (41) (Prebiotic effect) BALB/c (AFP) AFP LPS NO AFP Lactobacillus rhamnosus Lactobacillus fermentum (42) (AFP type-ii Arabinogalactan 29 kda) ph (43) (44 45) T ( TNF- IFN- ) (46 47) type-ii Arabinogalactan( 29 kda) (48-52) MCF-7 (49) CT-26 BALB/c 19
type-ii Arabinogalactan (44 49) 民間傳統功效 1 2 3 4 5 (53) (54) 30 (55) 1 2 3 鵤 4 5 ( ) 6 7 8 9 10 ( ) ( ) 11 ( ) 20
Journal of Taiwan Medicinal Plants (56) 1 ( ) (1) (2) 2 3(1) (2) 4 5 (57) 1 2 2 2 2 3 2 4 1 1 1 1 結論 : 049-2992687 545 5 參考文獻 : 1 2003 364 16-21 2 2010 http://www2.cmu.edu.tw/~cmcrdc/epaper/ detail.php?epaperno=8&class=c&id=71 3 Huang, T.C. et al (eds.). 2000. Flora of Taiwan. 2nd ed., 746-749. Taipei: Editorial Committee of the Flora of Taiwan. 4 1996 27(3) 169-172 5 2001(6) 288-289 6 2015 46(23) 3570-3576 7 2007 8 2016 9 Chang, C.N., L.C. Chou. 2007. Growth responses, enzyme activities, and component changes as influenced by Rhizoctonia Orchid mycorrhiza on Anoectochilus formosanus Hayata. Botanical Studies 48: 445-451. 10 1997 21
(Rhizoctonia spp.) 11 2003 50(2) : 197-202 12 Zhang, F.S., Lv, Y.L., Zhao, Y., Guo, S.X. 2013. Promoting role of an endophyte on the growth and contents of kinsenosides and flavonoids of Anoectochilus formosanus Hayata, a rare and threatened medicinal Orchidaceae plant. J Zhejiang Univ Sci B. 14(9):785-792. 13 Du, X.M., T. Yoshizawa, and Y. Shoyama. 1998. Butanolic acid glucoside composition of whole body and in vitro plantlets of Anoectochilus formosanus. Phytochemistry 49: 1925-1928. 14 Du X.M., N.Y. Sun, N, Irino, Y. Shoyama. 2000. Glycosidic constituents from in vitro Anoectochilus formosanus. Chem Pharm Bull 48(11):1803-1804. 15 2001-16 Wang, S.Y., Y.H. Kuo, H.N. Chang, P.L. Kang, H.S. Tsay, K.F. Lin, N.S. Yang, L.F. Shyur. 2002. Profiling and characterization antioxidant activities in Anoectochilus formosanus Hayata. J Agric Food Chem 50(7):1859-1865. 17 2000 90 11:19-29 18 2000 11:79-86 19 2001 ( ) 12(3): 173-178 20 1998 47(3) 242-258 21 2003 14(4) 235-245 22 Hsiao, H.B., J.B. Wu, H. Lin, W.C. Lin. 2011. Kinsenoside isolated from Anoectochilus formosanus suppresses LPSstimulated inflammatory reactions in macrophages and endotoxin shock in mice. Shock 35(2):184-190. 23 2013 24 Ikeuchi M., K. Yamaguchi, T. Nishimura, K. Yazawa. 2005. Effects of Anoectochilus formosanus on endurance capacity in mice. J Nutr Sci Vitaminol 51(1): 40-44. 25 Lin, J.M., C.C. Lin, H.F. Chiu, J.J. Yang, S.G. Lee. 1993. Evaluation of the anti-inflammatory and liver-protective effects of Anoectochilus formosanus, Ganoderma lucidum and Gynostemma pentaphyllum in rats. Am J Chin Med 21(1):59-69. 26 Lin, C.C., P.C. Huang, J.M. Lin. 2000. Antioxidant and hepatoprotective effects of Anoectochilus formosanus and Gynostemma pentaphyllum. Am J Chin Med 28(1):87-96. 27 Shih, C.C., Y.W. Wu, C.C. Hsieh, W.C. Lin. 2004. Effect of Anoectochilus formosanus on fibrosis and regeneration of the liver in rats. Clin Exp Pharmacol Physiol 31(9):620-625. 28 Shih, C.C., Y.W. Wu, W.C. Lin. 2005.Aqueous extract of Anoectochilus formosanus attenuate hepatic fibrosis induced by carbon tetrachloride in rats. Phytomedicine 12(6-7):453-460. 29 Fang, H.L., J.B. Wu, W.L. Lin, H.Y. Ho, W.C. Lin. 2008. Further studies on the hepatoprotective effects of Anoectochilus formosanus. Phytother Res 22(3):291-296. 30 Wu, J.B., H.R. Chuang, L.C. Yang, W.C Lin. 2010. A standardized aqueous extract of Anoectochilus formosanus ameliorated thioacetamide-induced liver fibrosis in mice: the role of Kupffer cells. Biosci Biotechnol Biochem 74(4):781-787. 31 Hsieh, W.T., C.T. Tsai, J.B. Wu, H.B., Hsiao L.C. Yang, W.C. Lin. 2011. Kinsenoside, a high yielding constituent from Anoectochilus formosanus, inhibits carbon tetrachloride induced Kupffer cells mediated liver damage. J Ethnopharmacol 135(2):440-449. 32 Du, X. M., N. Y. Sun, T. Tamura, A. Mohri, M. Sugiura, T. Yoshizawa, N. Irino, J. Hayashi, and Y. Shoyama. 2001. Higher yield isolation of kinsenoside in Anoectochilus and its antihyperliposis effect. Biol. Pharm Bull. 24: 65-69. 33 Du, X.M., N.Y. Sun, J. Hayashi, Y. Chen, M. Sugiura, Y. Shoyama. 2003. Hepatoprotective and antihyperliposis activities of in vitro cultured Anoectochilus formosanus. Phytother Res 17(1):30-33. 34 Shih, C.C., Y.W. Wu, W.C. Lin. 2002. Antihyperglycaemic and anti-oxidant properties of Anoectochilus formosanus in diabetic rats. Clin Exp Pharmacol Physiol 29(8):684-688. 35 Shih, C.C., Y.W. Wu, W.C. Lin. 2003. Scavenging of reactive oxygen species and inhibition of the oxidation of low density lipoprotein by the aqueous extraction of Anoectochilus formosanus. Am J Chin Med 31(1):25-36. 36 Du, X.M., N.Y. Sun, N. Furusho, J. Hayashi, Y. Shoyama. 2007. Effect of in vitro cultured Anoectochilus formosanus on lipid metabolism in clinical uses. Am J Chin Med 35(5):735-741. 37 2012 38 Shih, C.C., Y.W. Wu, W.C. Lin. 2001. Ameliorative effects of Anoectochilus formosanus extract on osteopenia in ovariectomized rats. J Ethnopharmacol 77(2-3):233-238. 39 2003 40 2007 41 Masuda, K., M. Ikeuchi, T. Koyama, K. Yamaguchi, J.T. Woo, T. Nishimura, K. Yazawa. 2008. Suppressive effects of Anoectochilus formosanus extract on osteoclast formation in vitro and bone resorption in vivo. J Bone Miner Metab 26(2):123-129. 42 2005 43 Yang, L.C., W.C. Lin, T.J. Lu. 2012. Characterization 22
Journal of Taiwan Medicinal Plants and prebiotic activity of aqueous extract and indigestible polysaccharide from Anoectochilus formosanus. J Agric Food Chem 60(35):8590-8599. 44 Tseng, C.C., H.F. Shang, L.F. Wang, B. Su, C.C. Hsu, H.Y. Kao, K.T. Cheng. 2006. Antitumor and immunostimulating e ff e c t s o f A n o e c t o c h i l u s f o r m o s a n u s H a y a t a. Phytomedicine 13(5):366-370. 45 2009 46 2004 47 2005 48 Yang L.C., T.J. Lu, W.C. Lin. 2013. A Type II Arabinogalactan from Anoectochilus formosanus for G-CSF Production in Macrophages and Leukopenia Improvement in CT26-Bearing Mice Treated with 5-Fluorouracil. Evid Based Complement Alternat Med 2013:458075. 49 Yang L.C., C.C. Hsieh, T.J. Lu, W.C. Lin. 2014. Structurally characterized arabinogalactan from Anoectochilus formosanus as an immuno-modulator against CT26 colon cancer in BALB/c mice. Phytomedicine 21(5):647-655. 50 Lai C.Y., L.C. Yang, W.C. Lin. 2015. Type II arabinogalactan from Anoectochilus formosanus induced dendritic cell maturation through TLR2 and TLR4. Phytomedicine 22(14):1207-1214. 51 Yang, L.C., C.Y. Lai, W.C. Lin. 2017. Natural killer cell-mediated cytotoxicity is increased by a type II arabinogalactan from Anoectochilus formosanus. Carbohydrate Polymers 155: 466-474. 52 Shyur, L.F., C.H. Chen, C.P. Lo, S.Y. Wang, P.L. Kang, S.J. Sun, C.A. Chang, C.M. Tzeng, N.S. Yang. 2004. Induction of apoptosis in MCF-7 human breast cancer cells by phytochemicals from Anoectochilus formosanus. J Biomed Sci 11(6):928-939. 53 1999 8 1 672-673 54 1965 1 86 55 勲 2011 30 12-16 56 2002 91-92 57 201376 山源藥草行 青草藥材批發 粉碎 加工 電話 :(04)26994928 26992948 台中市大肚區沙田路 3 段 734 巷 25 號 23
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