2005 2006 2 18

2005... 1... 1... 2... 4... 9... 13... 17... 19... 40... 41... 44... 103 1

2005 1 2 3 4 1 TIANJIN TASLY PHARMACEUTICAL CO.LTD. TASLY 2 3 1 022-26736699 022-26736721 E-mail liujf@tasly.com 1 022-26736223 022-26736721 E-mail zhaoying@tasly.com 4 1

2005 300402 http://www.tasly.com stock@tasly.com 5 http://www.sse.com.cn 6 A A A 600535 7 1998 4 30 2003 8 13 1200001001441 12011323944464X : : 231,971,822.92 193,514,199.68 194,035,849.00 772,434,704.63 216,866.87 232,725,025.93-1,201,552.64 2

2005 1,100,000.00-651,650.37 214,897,007.48 156,962,349.35 : : 712.88 1,400,000.00 638,331.56-651,650.37-1,500,000.00-183,150.30-225,893.09-521,649.32 [ 1] 2005 2004 : : 2003 (%) 1,465,866,925.04 1,301,841,253.53 12.60 1,055,761,424.52 231,971,822.92 215,343,895.89 7.72 176,475,085.30 193,514,199.68 171,278,731.92 12.98 141,187,561.99 194,035,849.00 171,661,845.73 13.03 140,925,814.78 0.68 0.60 13.33 0.50 % 14.79 14.27 3 0.52 0.53 0.72 14.83 14.30 % 12.65 15.56 14.84 % 12.92 214,897,007.48 203,266,603.31 5.72 59,004,359.33 0.75 0.71 5.72 0.21 2005 2004 12.67 2003 (%) 2,754,416,889.43 2,201,021,206.13 25.14 1,777,237,703.05 1,308,314,716.77 1,200,259,469.73 9.00 1,114,114,775.68

2005 4.59 4.21 9.00 3.91 4.49 4.17 7.67 3.88 : : 285,000,000.00 566,648,156.01 59,342,659.02 29,671,329.51 259,597,325.19 1,200,259,469.73 41,047.36 19,353,696.66 9,676,848.33 193,514,199.68 222,585,792.03 114,530,544.99 114,530,544.99 285,000,000.00 566,689,203.37 78,696,355.68 39,348,177.84 338,580,979.88 1,308,314,716.77 1) [ 1] 2) [ 2] 3) [ 3] 4) [ 4] [ 1] 1 1,598.92 2 23,011.59 3 16,436.85 [ 2] [ 3] [ 4] 1 a. 2005 1 30 2004 2004 2004 28,500 10 3.00 85,500,000.00 b. 2006 2 18 2005 2005 10% 5% 19,353,696.66 9,676,848.33 2 8,550.00 2006 2 18 2005 10 3.00 8,550.00 4

2005 1 : (%) (%) 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 3 210,000,000 73.68 0-21,750,000 0 0-21,750,000 188,250,000 66.05 210,000,000 73.68 0-21,750,000 0 0-21,750,000 188,250,000 66.05 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 75,000,000 26.32 0 21,750,000 0 0 21,750,000 96,750,000 33.95 2 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 75,000,000 26.32 0 21,750,000 0 0 21,750,000 96,750,000 33.95 285,000,000 100 0 0 0 285,000,000 100 : 2006-36,573,761 151,676,239 133,323,761 12-30 14,250,000 2007-1,213,393 150,462,846 134,537,154 1,213,393 12-30 2008-150,462,846 0 285,000,000 12-30 1 2005 12 19 2005 12 15-12 19 21,750,000 10 2.9 5

2005 36 2 2005 12 28 2005 12 30 3 2 (1) : : A 2002-08-08 14.7 50,000,000 2002-08-23 50,000,000 [2002]79 2002 8 8 5000 1.00 14.70 [2002] 141 5000 2002 8 23 (2) (3) 6

2005 1 9,005 : (%) 52.79 150,462,846 3,462,846 150,462,846 16,600,000 5.43 15,463,393-1,786,607 15,463,393 3.59 10,219,286-15,223,714 10,219,286 3.30 9,412,500-1,087,500 9,412,500 1.58 4,489,507 4,489,507 0 005L FH002 1.31 3,140,312 3,734,679 0 1.30 3,140,312 3,703,305 0 1.10 3,140,312 3,140,312 0 1.04 2,977,811-1,083,819 0 0.94 2,691,975-311,025 2,691,975 4,489,507 005L FH002 3,734,679 7 3,703,305 3,140,312 2,977,811 ( ) 2,613,441 UBS LIMITED 2,488,733 2,451,000 2,400,000 2,211,630

2005 60% 21.67% 18.33% 80% 1 6,804,000 [2005]1513 14,043,000 2005 12 22 2 21,750,000 2 : 2008-150,462,846 150,462,846, 36 12-30 2006-14,250,000, 12 12-30 15,463,393 24 2007-1,213,393 5% 12-30 2006-10,219,286 10,219,286, 12 12-30 2006-9,412,500 9,412,500, 12 12-30 2,691,975 2006-2,691,975, 12 12-30 3 1 22,788 2000 3 30 8

2005 2 3 4 50% 51% 3.59% 60% 52.79% 4 9

2005 : : ( ) [ ] 52 2005-2008- 09-09 09-09 0 0 0 600,000.00 929,389.31 1,529,389.31 68 2005-2008- 09-09 09-09 0 0 0-545,376.04 545,376.04 53 2005-2008- 09-09 09-09 0 0 0-545,376.04 545,376.04 43 2005-2008- 09-09 09-09 0 0 0-545,376.04 545,376.04 47 2005-2008- 09-09 09-09 0 0 0-545,376.04 545,376.04 39 2005-2008- 09-09 09-09 0 0 0 350,000.00 545,376.04 895,376.04 55 2005-2006- 09-09 04-28 0 0 0 50,000.00 175,690.33 225,690.33 58 2005-2008- 09-09 09-09 0 0 0 50,000.00 105,422.82 155,422.82 72 2005-2008- 09-09 09-09 0 0 0 50,000.00 175,690.33 225,690.33 53 2003-2006- 05-17 05-17 0 0 0-545,376.04 545,376.04 61 2003-2006- 05-17 05-17 0 0 0-175,690.33 175,690.33 38 2003-2006- 05-17 05-17 0 0 0-105,422.82 105,422.82 39 2003-2006- 05-17 05-17 0 0 0 300,000.00 175,690.33 475,690.33 45 2003-2006- 05-17 05-17 0 0 0 300,000.00 105,422.82 405,422.82 38 2005-2008- 09-09 09-09 0 0 0 300,000.00-300,000.00 43 2005-2008- 09-09 09-09 0 0 0 300,000.00 90,525.98 390,525.98 / / / / / 2,300,000.00 5,311,201.31 7,611,201.31 2005 2002-2004 5,311,201.31 5 (1) 10

2005 (2) (3) (4) (5) (6) Technomark (7) (8) 1982 (9) 1960 (10) (11) (12) 11

2005 (13) (14) (15) 2005 2 (16) 2004 7 2005 2 2005 2 2005 1 2008 1 2003 7 2006 7 2005 1 2008 1 2005 1 2008 1 2003 7 2006 7 1997 10 2005 1 2008 1 2003 7 2006 7 2005 1 2006 12 12

2005 1 2 2005 2001 2002,2004 2.6% 50% 50% 13

2005 2005 1 30 3,167 0 1 712 71 1,176 866 201 141 2 29 85 717 1,183 876 277 [2005]15 2004 14

2005 2005 http://www.sse.com.cn 1 2 3 2005 9 9 2005 4 15

2005 5 6 7 1 7 7 7 7 7 7 2 16

2005 1 2 3 4 17

2005 5 1 2 2002,2004 2.6% 50% 1 2005 4 16 2004 2005 4 19 1 2004 2 2004 18

2005 3 2004 4 2004 5 2004 6 2005 7 8 9 1 2005 5 22 2005 2005 5 24 1 < > 2 2 2005 9 9 2005 2005 9 13 1 2 3 2005 12 19 2005 12 20 19

2005 1. 1 2005 146,587 12.60 23,272 6.96% 19,351 12.98 20

2005 2 7 4 10 2005 471 10 PCT 2 1 233 231 2005 26 18 47 34 37 2005 6 5 21

2005 863 2004 OTC 25 191 1.5 2000 22

2005 2005 2005 119 A 21 109 98% 23

2005 G 70 GAP cgep GMP 10 863 2005 B GMP 24

2005 rhpro-uk (2) i. % % (%) 112060.28 76.44 33492.33 49.68 70.11 34526.41 23.55 33927.80 50.32 1.73 146586.69 100.00 67420.13 100.00 54.01 % % % 113256.15 77.26 36956.86 54.82 5.48 25.24 31341.82 21.38 28550.78 42.35 50.87 46.54 1477.22 1.01 1392.31 2.07 0.94-1.88 511.51 0.35 520.17 0.76-10.85 1.25 146586.69 100.00 67420.13 100.00 12.60 32.39 ii. iii. 386,05.76 26.34% 25,136.00 37.5 25

2005 (3) 2005 2004 % % % 9,007.52 3.27% 1,001.63 0.46% 2.82% 13,679.32 4.97% 12,809.00 5.82% -0.85% 37,925.68 13.77% 32,887.10 14.94% -1.17% 24,427.01 8.87% 12,496.98 5.68% 3.19% 11,706.13 4.25% 3,861.53 1.75% 2.50% 22,400.00 8.13% 0.00% 8.13% 275,441.69 220,102.12 i i 1 9000 iii 13679.32 870.32 4.97% 0.85 1012.69-97.04-39.71 5.62 iiii -2 1.16 5172.16 v 24427.01 95.46% 21842.33 7,600.00 10,000.00 2005 12 31 2584.68 vi 11706.13 vii 22400 13400 9000 26

2005 (4) 2005 2004 21,489.70 20,326.66 1,163.04-38,756.79-47,979.70 9,222.91 33,158.98 4,436.01 28,722.97-195.66-0.90-194.76 15,696.23-23,217.93 38,914.16 i 1163.04 3 1568.95 2341.39 ii 9222.91 7328.98 1844.26 iii 28722.97 17600 100,000,000.00 76,000,000.00 (5) i 2005 7900 70% " 27

2005 2005 58433.30 2005 132097.48 935.06 19.74% ii 2005 18539 84.73% 2005 21373.08 2005 13557.88 1042.32 89.24% iii 2005 6406.60 85.48% 2005 7025.97 2005 1637.18 115.35 44.42%. 2. 28

2005 3. 2006 2 9 12 1 2 29

2005 2006 2006 2006 rhpro-uk SPC 2006 6 IT 200 500 3 2006 30

2005 4 2005 9 17 8 6 GAP 8.8 2006 2006 31

2005 1 : : % (%) 1,120,602,835.71 334,923,274.06 68.80 5.83 20.76 3.73 345,264,089.33 339,278,020.85 1.70 42.11 46.31 2.77 1,465,866,925.04 674,201,294.91 52.69 12.60 32.39 6.89 1,132,561,461.71 369,568,585.00 66.06 5.48 25.24 5.16 313,418,169.04 285,507,845.17 7.57 50.87 46.54 2.66 14,772,236.15 13,923,143.61 4.44 0.94-1.88 2.69 5,115,058.14 5,201,721.13-1.69-10.85 1.25 10.86 1,465,866,925.04 674,201,294.91 52.69 12.60 32.39 6.89 2 : : ( ) 1,325,724,560.41 10.06 209,373,672.10 25.26 167,719,360.90 26.04 65,079,172.94 44,778,715.03 105.15 16,371,826.37 11.05 9,407,628.31 41.75 156,721.67-69.18 6,551,009.78 23.97 32

2005 1,838,611,657.73 18.71 372,744,732.69 50.93 1,465,866,925.04 12.60 93,030,599.15-2.83 544,384,396.02 29.15 406,298,277.99-4.04 63,215,709.63 50.09 48,466,208.53-2.31 310,471,733.72 15.21 1,465,866,925.04 12.60 40,398.89 8,688.88-17.70 29,632.67 10,261.00 505.23 (%) : 73.00 : 29.27 670.00 469.00 70.00% 201.00 30.00% 10.00% 20.00% 10.00% 63.00% 73.00% 33

2005 1 1) 2002 71,125.68 71,125.68 2004 2005 12 31 56 489.08 2 : : 4,750.00 4,750.00 4,850.00 4,850.00 7,857.00 5,000.00 9,486.00 500.00 13,704.00 13,704.00 51,871.90 4,993.00 4,993.00 4,697.30 4,950.00 4,950.00 2,980.00 2,980.00 FDA 3,200.00 3,200.00 2,748.96 1,748.45-80.12 12,851.00 15,708.00 9,000.00 9,000.00 81,396.96 / 71,383.45 56,489.08 / / GLP GAP GEP GMP GSP FDA 1) 4,750.00 4,750.00 100 564.26 953.05 3,232.69 34

2005 30 10 2) 4,850.00 4,850.00 100.00% 2002 2005 4,092.32 757.68 U-PA III U-PA 3) 7,857.00 5,000.00 70.00% 2003 GAP 2003 7 2003 7 2004 5 18 2004 6 19 2003 7,857.00 5,000.00 GAP 8 4) 9,486.00 500.00 70.00% 2003 11 9 2003 12 13 2003 9,486.00 500.00 500 GAP 8986 2003 11 9 35

2005 2003 11 12 2003 12 23 2003 2004 5 18 2004 6 19 2003 2004 5 20 2004 6 22 5) 13,704.00 13,704.00 100 13,704.00, 5,000.00 8,704.00 2001 7 2002 2 2002 2005 51871.90 6) 4,993.00 4,993.00 100 2,327.09 2,665.91 2004 2004 2005 4697.30 7) 4,950.00 4,950.00 85.00% 4,668.80 281.20 85 8) 2,980.00 2,980.00 100 2,645.00 335.00 23 OTC 2002 9) FDA 3,200.00 3,200.00 2005 6 30 FDA 3,200.00 FDA 10) 2,748.96 1,748.45 2003 3 22 2003 5 17 2002 36

2005 2,748.96 1,748.45 181.51 GLP ( 2748.96 ) 1,815,121 50% 1,000.51 2003 3 22 2003 3 25 2003 5 17 2002 2003 5 23 1,000.51 2004 5 18 2004 6 19 2003 2004 5 20 2004 6 22 100 2003 5 50% 2005 12 31-80.12 11) 12,851.00 15,708.00 1 23,983.00 17,687.00 73.74% 7,951.00 2004 5 18 2004 6 19 2003 7,951.00 2 2004 5 18 37

2005 2004 6 19 2003 4,900.00 2,857.00 7,757.00 2003 3 2004 6 4900 2,857.00 7,857.00 5,000.00 7,951.00 15,708.00 2004 5 18 2004 6 19 2003 2004 5 20 2004 6 22 50.00% 2003 2003 3 2004 12 31 7,267.62 2003 8 2004 12 31 4,342.59 12) 9,000.00 9,000.00 70.00% 2003 11 9 2003 12 13 2003 9,000.00 2003 12 2004 38

2005 3 : : 1,748.45 1,748.45 / -80.12 4,900.00 4,900.00 / / / 6,648.45 6,648.45 / -80.12 / / 1) 1,748.45 1,748.45 2) 4,900.00 4,900.00 4 1) 177,792,890.44 2) 34,779,633.90 70.00% 3) 6,943,478.63 4) 51,721,641.80 85.00% 39

2005 1 1 2005 30 2005 2 1 2 2005 3 10 2005 3 14 3 2005 4 16 2005 4 19 4 2005 5 22 2005 5 24 5 2005 8 6 2005 8 9 6 2005 9 9 2005 9 13 7 2005 10 18 2005 2 2004 2004 2004 28,500 10 3 85,500,000 2005 5 18 2005 5 19 2005 5 25 2005 5 13 40

2005 2005 193,514,199.68 193,536,966.64 10% 19,353,696.66 5% 9,676,848.33 259,597,325.19 2005 2004 85,500,000 2005 338,580,979.88 2005 28500 10 3 85,500,000 253,080,979.88 2005 2005 1 31 1. 2004 2. 2004 3. 2004 4. 2005 41

2005 2005 2005 2002 8 8 71,125.68 2004 56,489.08 2005 42

2005 1 : : 1,090.69 2,000.00 11.22 68.25 72.18 72.18-14.91 384.80 1,371.83 4,555.16 125.00 125.00-175.13 0.86-8.50 25.65 25.65 70.13 70.13-3,010.90-4,785.90 1,845.57-882.08 40,699.00 6,863.17 13,068.17-202.77-0.40-58.00-29.00 258.67 354.26 120.19 120.19 63.76 63.76-1.99-5,234.46 / -2,224.70 54,441.86-2,106.85 9,011.12-2,224.70 54,441.86 43

2005 2005 1 1 2005 12 31 73,355.48 880,265.76 880,265.76 11,000 11,000 11,000 (%) 8.41 1 2004 10 23 6,000.00 2004 12 31 131,189,985.31 44

2005 2 WORDIDUL SPINE HOSPITAL DOCTOR MEDICORE CO.,LTD 2004 9 1 18,300.00 10,000.00 55.00% 2005 2 2005 6 3,000.00 7,000.00 2005 2 1 2 3 4 2004 7 31 2004 2004 9 4 2005 9 3 2005 8 6 2004 2006 9 3 5 2006 2 18 6 1,660.00 2005 11 21 2006 5 21 2005 11 23 45

2005 [2006] 56 2005 12 31 2005 2005 2005 12 31 2005 2005 2 18 46

2005 2005 12 31 : : : 6.1 565,517,562.62 390,642,418.95 235,425,451.45 74,810,279.15 6.2 90,075,168.00 10,016,333.33 210,296,818.00 6.3 124,034,038.11 149,081,013.77 85,267,327.36 205,376,000.00 6.4 7.1 270,049,567.75 220,144,797.64 310,969,514.50 194,285,883.45 6.5 7.2 34,397,793.27 29,798,086.19 26,951,879.71 92,738,540.08 6.6 146,919,061.99 213,552,605.14 106,780,050.25 149,557,621.98 6.7 756,496.61 6.8 92,631,871.21 83,672,182.94 28,762,596.72 42,145,294.70 6.9 186,421.04 328,762.98 1,324,567,980.60 1,097,236,200.94 1,004,453,637.99 758,913,619.36 6.10 7.3 136,793,150.32 128,090,034.52 784,167,810.08 662,270,943.93 136,793,150.32 128,090,034.52 784,167,810.08 662,270,943.93 ( - 282,736.75 ) 486,068.67 ( - 1,853,652.75 2,620,681.48 2,467,275.38 3,397,143.75 ) 6.11 937,061,842.90 567,627,931.81 778,294,334.06 455,242,747.91 6.12 156,047,256.08 107,242,677.19 128,673,092.95 88,634,877.77 6.13 781,014,586.82 460,385,254.62 649,621,241.11 366,607,870.14 781,014,586.82 460,385,254.62 649,621,241.11 366,607,870.14 6.14 16,609,094.37 74,425,592.82 4,100,834.74 3,859,492.82 6.15 379,256,753.15 328,871,023.78 83,672,833.99 211,663,642.73 1,176,880,434.34 863,681,871.22 737,394,909.84 582,131,005.69 6.16 88,956,949.31 100,275,424.00 29,456,949.31 33,457,163.15 6.17 27,218,374.86 11,737,675.45 1,666,666.44 116,175,324.17 112,013,099.45 29,456,949.31 35,123,829.59 2,754,416,889.43 2,201,021,206.13 2,555,473,307.22 2,038,439,398.57 47

2005 6.18 445,000,000.00 453,731,700.00 425,000,000.00 415,000,000.00 6.19 244,270,143.28 124,969,839.96 96,997,135.71 111,110,586.40 6.20 117,061,291.65 38,615,296.19 252,546,013.39 66,038,112.59 6.21 7,422,547.15 13,786,739.38 6.22 39,340.99 5,281,163.36 4,745,200.00 32,772,154.23 25,825,466.16 29,895,993.90 24,101,717.41 6.23 9,800,000.00 6,650,000.00 9,800,000.00 6,650,000.00 6.24 24,966,940.22 53,801,674.82 27,943,251.21 43,402,420.79 6.25 1,040,924.26 1,235,043.33 855,202.08 1,025,545.79 6.26 43,718,002.19 40,619,167.33 306,200,722.22 107,826,226.38 6.27 886,050.59 753,449.81 582,923.00 665,537.50 6.28 10,000,000.00 36,000,000.00 36,000,000.00 936,977,394.56 801,269,540.34 1,149,821,241.51 816,565,346.86 6.29 224,000,000.00 74,000,000.00 6.30 16,000,000.00 16,000,000.00 16,000,000.00 16,000,000.00 6.31 12,527,500.00 9,145,765.64 7,927,500.00 6,227,500.00 252,527,500.00 25,145,765.64 97,927,500.00 22,227,500.00 1,189,504,894.56 826,415,305.98 1,247,748,741.51 838,792,846.86 ( ) 256,597,278.10 174,346,430.42 6.32 285,000,000.00 285,000,000.00 285,000,000.00 285,000,000.00 285,000,000.00 285,000,000.00 285,000,000.00 285,000,000.00 6.33 566,689,203.37 566,648,156.01 566,689,203.37 566,648,156.01 6.34 118,044,533.52 89,013,988.53 118,044,533.52 89,013,988.53 39,348,177.84 29,671,329.51 39,348,177.84 29,671,329.51 6.35 338,580,979.88 259,597,325.19 337,990,828.82 258,984,407.17 85,500,000.00 85,500,000.00 85,500,000.00 85,500,000.00 ( ) ( ) 1,308,314,716.77 1,200,259,469.73 1,307,724,565.71 1,199,646,551.71 2,754,416,889.43 2,201,021,206.13 2,555,473,307.22 2,038,439,398.57 : : : 48

2005 2005 1-12 : : : 6.36 7.4 1,465,866,925.04 1,301,841,253.53 1,045,607,076.53 982,336,843.24 6.36 7.5 674,201,294.91 509,239,751.23 392,791,500.56 308,858,461.97 6.37 19,230,925.50 16,904,611.51 14,326,428.24 13,329,837.72 772,434,704.63 775,696,890.79 638,489,147.73 660,148,543.55-216,866.87-63,620.43 29,765,587.57 15,704,182.16 - : 317,556,447.37 325,899,260.64 288,819,002.96 298,821,546.80 178,323,490.69 209,472,773.08 140,292,385.41 178,627,327.31 6.38 44,046,607.51 22,671,764.98 35,958,524.88 15,339,680.79-232,725,025.93 217,589,471.66 203,184,822.05 183,064,170.81-6.39 7.6-1,201,552.64-659,028.18 13,109,342.76 8,872,670.64 6.40 1,100,000.00 50,000.00 28,210.93 803,329.67 10,400.00 400,948.18 679,861.30 2,439,877.26 467,974.54 2,123,651.15 231,971,822.92 215,343,895.89 215,836,590.27 190,214,138.48-37,368,654.23 40,718,868.76 22,299,623.63 26,272,390.64 1,088,969.01 3,346,295.21 ( ) - 193,514,199.68 171,278,731.92 193,536,966.64 163,941,747.84 259,597,325.19 198,409,855.44 258,984,407.17 205,133,921.50 453,111,524.87 369,688,587.36 452,521,373.81 369,075,669.34 19,353,696.66 16,394,174.78 19,353,696.66 16,394,174.78 9,676,848.33 8,197,087.39 9,676,848.33 8,197,087.39 49

2005 ( ) 424,080,979.88 345,097,325.19 423,490,828.82 344,484,407.17 85,500,000.00 85,500,000.00 85,500,000.00 85,500,000.00 ( - ) 338,580,979.88 259,597,325.19 337,990,828.82 258,984,407.17 1. 712.88-292,007.36 2. 3. ( ) 4. ( ) -472,157.14-249,607.37 5. 6. : : : 50

2005 2005 1-12 : : : 51 1,669,816,052. 40 1,114,865,275.95 6.41 21,990,415.08 92,610,233.40 1,691,806,467. 48 1,207,475,509.35 670,365,694.93 188,690,230.13 140,028,213.72 110,473,668.22 254,818,494.04 200,144,238.01 6.42 411,697,057.31 340,217,392.95 1,476,909,460. 00 839,525,529.31 214,897,007.48 367,949,980.04 10,057,000.00 60,000,000.00 579,496.89 2,226,705.97 1,637,319.24 6.43 4,147,234.30 1,514,242.37 16,421,050.43 63,740,948.34 296,326,696.25 134,113,935.67 102,610,000.00 381,270,000.00 2,010,000.00 6.44 5,052,250.00 403,988,946.25 515,383,935.67 - -451,642,987.33 387,567,895.82 83,212,926.03 83,212,926.03 984,000,000.00 935,994,158.16 6.45 177,300,000.00 100,300,000.00 1,244,512,926. 03 1,036,294,158.16 774,731,700.00 676,000,000.00 112,770,266.90 112,985,978.57

2005 6.46 25,421,166.67 6,000,000.00 912,923,133.57 794,985,978.57 331,589,792.46 241,308,179.59-1,956,554.77 156,962,349.35 157,615,172.30 1 193,514,199.68 193,536,966.64 ( - ) 1,088,969.01-5,076,482.73 876,696.60 49,860,304.23 40,051,487.61 7,818,474.69 7,300,213.84 1,871,468.57 1,666,666.44 142,341.94-297.31-8,179.53 ( : ) 216,746.57 7,397.57 27,322,527.63 27,944,241.70 1,201,552.64-13,109,342.76-876,029.07 15,142,068.92 ( ) -11,324,628.78-3,119,093.85 ( ) -50,853,960.06 97,652,677.33 ( ) 214,897,007.48 367,949,980.04 2 3 531,915,312.62 229,425,451.45 374,952,963.27 71,810,279.15 156,962,349.35 157,615,172.30 : : : 52

2005 2005 : : : 1 13,651,896.14 3,007,176.47 / / 16,659,072.61 2 11,636,081.52 2,818,602.62 / / 14,454,684.14 3 2,015,814.62 188,573.85 / / 2,204,388.47 4 5 6 7 12,328,763.67 8,083,659.20 8,083,659.20 4,245,104.47 8 9 12,328,763.67 8,083,659.20 8,083,659.20 4,245,104.47 10 11 12 13 14 15 16 17 18 19 20 21 25,980,659.81 3,007,176.47 8,083,659.20 8,083,659.20 20,904,177.08 : : : 53

2005 2005 : : : 1 15,369,293.21 6,179,281.16 / / 3,543,213.62 18,005,360.75 2 10,242,529.57 6,179,281.16 / / 16,421,810.73 3 5,126,763.64 / / 3,543,213.62 1,583,550.02 4 5 6 7 6,004,475.41 1,759,370.94 1,759,370.94 4,245,104.47 8 9 6,004,475.41 1,759,370.94 1,759,370.94 4,245,104.47 10 11 12 13 14 15 16 17 18 19 20 21 21,373,768.62 6,179,281.16 1,759,370.94 5,302,584.56 22,250,465.22 : : : 54

2005 9 : : % 59.04 61.94 2.71 2.71 17.79 18.66 0.82 0.82 14.79 15.52 0.68 0.68 14.83 15.56 0.68 0.68 2005 [2000]4 ( ) 7 2000 4 30 1200001001441 285,000,000.00 285,000,000 1 96,750,000 188,250,000 2002 8 23 2005 12 31 ( ) ( ) 1 1 12 31 55

2005 ( ) ( ) ( ) 1 ( ) 1 2 ( ) 3 ( ) 1 2 ( ) 1 1 1 56

2005 5% 1-2 10% 2 3 20% 3-5 50% 5 100% 2 : (1) (2) ( ) 1 2 3 4 ( ) 1 20% 20% 20% 20% 20% 20% 2 10 10 [2003]10 10 -- 3 57

2005 4 ( ) 1 2 3 ( ) 1 (1) (2) (3) 2 3 5% ( ) (%) 15-35 6.33-2.71 4-11 23.75-8.64 4-18 23.75-5.28 6-10 15.83-9.50 4-8 23.75-11.88 5 20.00 4 ( ) 1 2 3 58

2005 (1) 3 (2) (3) ( ) 1 2 (1) 1) 2) 3) (2) 3 (3) 3 ( ) 1 2 (1) (2) (3) 10 3 59

2005 ( ) 1 2 ( ) ( ) 1 2 (1) (2) 3 (1) (2) ( ) ( ) 60

2005 ( ) 17% 13% ( ) 5% ( ) 7% ( ) 3% 1% ( ) [94]001 15% [94]001 2004 2005 2002 2 15% 33% % 7,900.00 5,530.0 70.00 [ 1] 0 " 6,406.60 5,476.6 85.48 3 900.00 97.96 [ 2] 900.00 300.00 79.30 [ 3] 61

2005 300.00 18,539.00 15,708. 84.73 00 10,000.00 90.00 9,000.0 0 4,800.00 3,600.00 75.00 100.00 75.00 75.00 50.00 87.78 [ 4] 50.00 100.00 70.00 70.00 19,590.00 11,754. 60.00 00 670.00 : 489.10 73.00 [ 5] : 18,300.00, 10,000. 55.00 00 [ 1] [ 2] 86.67% 11.29% 97.96% [ 3] 31.00% 48.30% 79.30% [ 4] 20.00% 67.78% 87.78% [ 5] 670.00 469.00 62

2005 70.00% 201.00 30.00% 10.00% 20.00% 10.00% 63.00% 73.00% ( ) 1 2 50% 3 (1) WORDIDUL SPINE HOSPITAL DOCTOR MEDICORE CO.,LTD 2004 9 1 18,300.00 10,000.00 55.00% 2005 2 2005 6 3,000.00 7,000.00 2005 2 (2) 2005 1 30 2004 2004 2004 10% 5% 10 3.00 2006 2 18 2005 2005 10% 5% 10 3.00 ( ) 1. 565,517,562.62 (1) 187,636.43 390,138.90 525,479,154.56 358,739,027.01 63

2005 39,850,771.63 [ ] 31,513,253.04 565,517,562.62 390,642,418.95 [ ] 39,850,771.63 39,053,630.00 797,141.63 (2) USD34,582.14 8.0702 279,084.79 279,084.79 2. 90,075,168.00 (1) 90,075,168.00 90,075,168.00 10,016,333.33 10,016,333.33 90,075,168.00 90,075,168.00 10,016,333.33 10,016,333.33 (2) 1) 1 10,000,000.00 10,000,000.00 80,000,000.00 75,168.00 80,075,168.00 90,000,000.00 75,168.00 90,075,168.00 2) 10% 10% 2005.12.30 10,000,000.00 2005.12.26 80,075,168.00 75,168.00 90,075,168.00 75,168.00 3) 3. 124,034,038.11 (1) 13,849,639.81 130,349,313.77 64

2005 110,184,398.30 18,731,700.00 124,034,038.11 149,081,013.77 (2) 5% 5% 4. 270,049,567.75 (1) (%) (%) 1 281,032,091.83 98.78 14,051,604.59 266,980,487.24 231,123,745.48 99.72 11,556,187.27 219,567,558.21 1-2 2,980,306.20 1.05 298,030.62 2,682,275.58 600,168.54 0.26 60,016.85 540,151.69 2-3 469,593.34 0.16 93,918.67 375,674.67 28,683.90 0.01 5,736.78 22,947.12 3-5 22,260.52 0.01 11,130.26 11,130.26 28,281.24 0.01 14,140.62 14,140.62 284,504,251.89 100.00 14,454,684.14 270,049,567.75 231,780,879.16 100.00 11,636,081.52 220,144,797.64 (2) 611,244.02 8.0702 4,932,861.49 4,932,861.49 (3) 5 89,370,435.69 31.41% (4) 5% 5% (5) 345,352.99 305,005.40 212,080.90 172,917.27 458,462.56 1,189,482.59 2,683,301.71 5. 34,397,793.27 (1) (%) (%) 1 32,086,029.94 87.66 1,604,301.50 30,481,728.44 26,451,515.49 83.14 1,322,575.77 25,128,939.72 1-2 3,702,884.81 10.12 370,288.48 3,332,596.33 4,057,721.56 12.75 405,772.16 3,651,949.40 2-3 589,783.35 1.61 117,956.67 471,826.68 1,216,550.62 3.82 243,310.12 973,240.50 65

2005 3-5 223,283.64 0.61 111,641.82 111,641.82 87,913.14 0.28 43,956.57 43,956.57 5 200.00 0.00 200.00 0.00 200.00 0.01 200.00 0.00 36,602,181.74 100.00 2,204,388.47 34,397,793.27 31,813,900.81 100.00 2,015,814.62 29,798,086.19 (2) 3,000,000.00 3,000,000.00 (3) 5 6,490,168.16 17.73% (4) 5% 5% 6. 146,919,061.99 (1) (%) (%) 1 26,524,561.99 18.06 109,726,539.34 51.38 1-2 68,542,500.00 46.65 68,784,065.80 32.21 2-3 16,810,000.00 11.44 5,042,000.00 2.36 3-5 35,042,000.00 23.85 30,000,000.00 14.05 146,919,061.99 100.00 213,552,605.14 100.00 (2) 5% 5% (3) 1 1-2 68,952,500.00 100ml pichia -2 ( ) 68,950,000.00 2 3 16,400,000.00-3 H ( ) 16,400,000.00 66

2005 3 5 35,042,000.00, u-pa 35,000,000.00 7. 756,496.61 (1) 756,496.61 756,496.61 (2) 8. 92,631,871.21 (1) 19,806,784.83 4,245,104.47 15,561,680.36 31,760,618.89 12,328,763.67 19,431,855.22 3,224,012.11 3,224,012.11 13,369,244.63 13,369,244.63 595,581.81 595,581.81 435,837.23 435,837.23 59,409,136.89 59,409,136.89 44,144,734.34 44,144,734.34 978,844.14 978,844.14 346,795.32 346,795.32 12,862,615.90 12,862,615.90 5,943,716.20 5,943,716.20 96,876,975.68 4,245,104.47 92,631,871.21 96,000,946.61 12,328,763.67 83,672,182.94 (2) (3) (4) 1) 12,328,763.67 8,083,659.20 4,245,104.47 12,328,763.67 8,083,659.20 4,245,104.47 67

2005 2) 9. 186,421.04 184,510.21 328,174.98 2006 588.00 1,910.83 186,421.04 328,762.98 10. 136,793,150.32 (1) 282,736.75 282,736.75 486,068.67 486,068.67 135,257,781.57 135,257,781.57 126,295,046.73 126,295,046.73 1,252,632.00 1,252,632.00 1,308,919.12 1,308,919.12 136,793,150.32 136,793,150.32 128,090,034.52 128,090,034.52 (2) 1) a. 70.00-1,331,395.48-1,331,395.48 97.96 20 1,276,941.52 1,276,941.52 79.30 20 337,190.71 337,190.71 50.00 17 13,647,992.94-1,332,532.08 1,853,652.75 14,169,113.61 [ ] 29.27 20 120,126,896.14 961,771.82 121,088,667.96 133,774,889.08-370,760.26 2,136,389.50 135,540,518.32 [ ] 36,302.00 50.00% 5 2 68

2005 b. -1,597,674.59 266,279.11-1,331,395.48 1,533,707.02-256,765.50 1,276,941.52 550,036.24-212,845.53 337,190.71 16,295,046.73-1,358,904.39-767,028.73 14,169,113.61 110,000,000.00 10,126,896.14 961,771.82 121,088,667.96 126,781,115.40 10,126,896.14-397,132.57-970,360.65 135,540,518.32 2) / a. -2,662,791.13-1,597,674.59-266,279.11-1,331,395.48 10 2,567,654.97 1,533,707.02 256,765.50 1,276,941.52 10 1,016,220.04 550,036.24 212,845.53 337,190.71 5 3,835,143.63 2,620,681.48 767,028.73 1,853,652.75 5 473,103.86 473,103.86 473,103.86 5,229,331.37 3,106,750.15 473,103.86 1,443,464.51 2,136,389.50 b. / 69

2005 (4) (3) 10% 50 200,000.00 200,000.00 10% 20 56,287.12 56,287.12 5% 1,052,632.00 1,052,632.00 1,308,919.12 56,287.12 1,252,632.00 11. 937,061,842.90 (1) 301,887,239.53 284,285,244.35 5,793,000.00 580,379,483.88 90,847,197.35 56,866,699.51 591,157.38 147,122,739.48 112,763,166.37 15,261,545.91 231,604.00 127,793,108.28 46,095,544.59 3,566,001.82 4,669.00 49,656,877.41 14,978,913.97 16,094,712.88 19,863.00 31,053,763.85 1,055,870.00 1,055,870.00 567,627,931.81 376,074,204.47 6,640,293.38 937,061,842.90 (2) 251,782,144.49 (3) 155,354.38 30,739.00 6,454,200.00 (4) 70

2005 (5) 10,838,583.04 916,616.12 9,921,966.92 10,838,583.04 916,616.12 9,921,966.92 (6) (7) 4,246,392.59 4,034,933.66 211,458.93 1,578,577.55 1,501,300.10 77,277.45 5,190,434.40 4,930,912.68 259,521.72 316,788.53 300,949.10 15,839.43 11,332,193.07 10,768,095.54 564,097.53 (8) (9) (10) 301,887,239.53 18,258,945.09 284,285,244.35 109,636.43 12 156,047,256.08 31,070,421.80 11,906,651.91 897,452.58 42,079,621.13 23,635,077.18 13,534,478.66 133,452.72 37,036,103.12 25,681,206.66 14,387,241.89 13,742.32 40,054,706.23 20,238,299.73 6,710,362.70 1,852.48 26,946,809.95 6,212,530.82 3,100,583.07 9,225.24 9,303,888.65 405,141.00 220,986.00 626,127.00 107,242,677.19 49,860,304.23 1,055,725.34 156,047,256.08 71

2005 13 781,014,586.82 (1) 538,299,862.75 270,816,817.73 110,086,636.36 67,212,120.17 87,738,402.05 87,081,959.71 22,710,067.46 25,857,244.86 21,749,875.20 8,766,383.15 429,743.00 650,729.00 781,014,586.82 460,385,254.62 (2) 14. 16,609,094.37 193,767.00 37,558.00 16,415,327.37 74,388,034.82 16,609,094.37 74,425,592.82 15. 379,256,753.15 (1) 76,809,597.29 76,809,597.29 ( ) 45,868,072.39 45,868,072.39 43,425,870.89 43,425,870.89 28,129,484.80 28,129,484.80 5,379,633.90 5,379,633.90 5,722,114.00 5,722,114.00 19,206,333.76 19,206,333.76 17,009,579.06 17,009,579.06 56,128,877.85 56,128,877.85 47,184,255.88 47,184,255.88 32,805,487.48 32,805,487.48-2 183,720,281.94 183,720,281.94 67,284,175.49 67,284,175.49 72

2005 11,167,172.99 11,167,172.99 4,846,000.00 4,846,000.00 2,133,702.00 2,133,702.00 51,721,641.80 51,721,641.80 6,064,738.52 6,064,738.52 3,520,756.89 3,520,756.89 379,256,753.15 379,256,753.15 328,871,023.78 328,871,023.78 2 % 76,809,597.29 64,528,046.66 141,337,643.95 11,050 127.91 [ 1] 43,425,870.89 21,867,762.28 19,425,560.78 45,868,072.39 18,200 36.31 ( ) 28,129,484.80 12,658,915.20 40,788,400.00 4,215 96.77 5,722,114.00 2,597,519.90 2,940,000.00 5,379,633.90 2,155 70.13 17,009,579.06 2,196,754.70 19,206,333.76 3,134 119.38 [ 2] 47,184,255.88 8,944,621.97 56,128,877.85 6,332.29 88.64 [ 3] 32,805,487.48 3,649,759.01 36,455,246.49 [ 4] 67,284,175.49 116,436,106.45 183,720,281.94 16,300 112.71 [ 5] -2 4,846,000.00 6,321,172.99 11,167,172.99 2,920 38.24 2,133,702.00 4,809,776.63 6,943,478.63 2,645 26.25 51,721,641.80 51,721,641.80 17,301 29.90 3,520,756.89 6,703,378.27 3,891,814.64 267,582.00 6,064,738.52 328,871,023.78 302,435,455.86 251,782,144.49 267,582.00 379,256,753.15 [ 1] [ 2] [ 3] 6,332.29 4,950.00 73

2005 [ 4] [ 5] (3) 794,880.00 794,880.00 5.76% 967,744.50 967,744.50 5.85% ( ) 768,500.00 768,500.00 5.22% -2 2,531,124.50 794,880.00 1,736,244.50 (4) 16. 88,956,949.31 (1) 5,247,782.81 5,247,782.81 5,372,996.57 5,372,996.57 600,000.00 600,000.00 1,533,333.21 1,533,333.21 2,333,333.25 2,333,333.25 3,833,333.21 3,833,333.21 5,833,333.25 5,833,333.25 15,437,500.12 15,437,500.12 18,687,500.08 18,687,500.08 120,000.00 120,000.00 398,260.85 398,260.85 489,999.96 489,999.96 630,000.00 630,000.00 59,500,000.00 59,500,000.00 66,300,000.00 66,300,000.00 1,347,500.00 1,347,500.00 1,567,500.00 1,567,500.00 88,956,949.31 88,956,949.31 100,275,424.00 100,275,424.00 74

2005 (2) ( ) 6,260,685.48 5,372,996.57 125,213.76 5,247,782.81 1,012,902.67 503 12,000,000.00 600,000.00 600,000.00 12,000,000.00 4,000,000.00 2,333,333.25 800,000.04 1,533,333.21 2,466,666.79 23 10,000,000.00 5,833,333.25 2,000,000.04 3,833,333.21 6,166,666.79 23 26,000,000.00 18,687,500.08 3,249,999.96 15,437,500.12 10,562,499.88 57 310,000.00 120,000.00 120,000.00 310,000.00 1,230,000.00 398,260.85 398,260.85 1,230,000.00 700,000.00 630,000.00 140,000.04 489,999.96 210,000.04 42 68,000,000.00 66,300,000.00 6,800,000.00 59,500,000.00 8,500,000.00 105 1,650,000.00 1,650,000.00 302,500.00 1,347,500.00 302,500.00 49 1,650,000.00 1,650,000.00 82,500.00 1,567,500.00 82,500.00 57 131,800,685.48 100,275,424.00 3,300,000.00 14,618,474.69 88,956,949.31 42,843,736.17 (3) (5) 17. 27,218,374.86 26,923,457.75 9,571,289.77 17,352,167.98 13,242.80 26,910,214.95 13,242.80 [ 1] 5,000,000.00 1,666,666.44 1,666,666.44 5,000,000.00 [ 2] 756,908.54 417,776.24 162,555.33 255,220.91 557,564.93 1.42-1.46 75

2005 PM3 120,000.00 62,000.00 24,000.00 38,000.00 82,000.00 1.58 32,036.00 19,943.00 5,004.00 14,939.00 17,097.00 3.0 32,832,402.29 11,737,675.45 17,352,167.98 1,871,468.57 27,218,374.86 5,669,904.73 [ 1]: [ 2] 2003 1 2003 500.00 2003 1 1 18. 445,000,000.00 305,000,000.00 333,731,700.00 3,000,000.00 57,000,000.00 120,000,000.00 80,000,000.00[ ] 445,000,000.00 453,731,700.00 [ ] 80,000,000.00 19. 244,270,143.28 (1) 218,423,310.40[ ] 19,888,274.08 25,846,832.88 105,081,565.88 244,270,143.28 124,969,839.96 [ ] 7,600.00 10,000.00 2005 12 31 76

2005 (2) 5% 5% 20. 117,061,291.65 (1) 5% 5% (2) 3 21. 7,422,547.15 (1) 5% 5% (2) 1 22 39,340.99 23. 9,800,000.00 (2) 9,800,000.00 6,650,000.00 9,800,000.00 6,650,000.00 (2) 2003 3 22 2003 5 17 2002 2002 2004 3 7 2004 6 19 2003 2003 2005 1 30 2005 4 16 2004 2004 980.00 24. 24,966,940.22 14,962,213.49 23,753,638.73 17% 13% 431,456.68 894,183.28 5% 1,608,723.24 1,949,829.82 7% 7,944,748.65 26,324,768.55 15% 33% 15,407.75 879,254.44 4,390.41 24,966,940.22 53,801,674.82 77

2005 25 1,040,924.26 689,627.95 835,881.32 3% 1% 350,071.18 397,659.05 1% 0.13% 1,225.13 1,502.96 1% 1,040,924.26 1,235,043.33 26. 43,718,002.19 (1) 5% 5% 20,000,000.00 9,093,089.72 20,000,000.00 9,093,089.72 (2) 3 (3) 20,000,000.00 4,706,036.16 [ ] 24,706,036.16 [ ] 2003 3 22 2.60% 50% 50% 2004 7 31 2004 50% 50% 2005 12 31 11,188,188.24 6,482,152.08 4,706,036.16 27. 886,050.59 886,050.59 753,152.50 297.31 886,050.59 753,449.81 78

2005 28. 10,000,000.00 (1) 10,000,000.00 36,000,000.00 10,000,000.00 36,000,000.00 (2) 10,000,000.00 36,000,000.00 10,000,000.00 36,000,000.00 29. 224,000,000.00 54,000,000.00 170,000,000.00 224,000,000.00 30 16,000,000.00 2003-2010 16,000,000.00[ ] 16,000,000.00 16,000,000.00 16,000,000.00 [ ]: 2002 10 19,, 2002 1,000.00 ( ) 2003 2010 8, 200 2,600.00 1,600.00 GMP 2002 2003 2004 2005 2006 79

2005 31 12,527,500.00 12,527,500.00[ ] 9,145,765.64 12,527,500.00 9,145,765.64 [ ] 12,527,500.00 1 2002 UPA 1,000,000.00 2 2003 400,000.00 3 2002 600,000.00 4 [2003]21 2003 150,000.00 112,500.00 37,500.00 5 2005 50,000.00 6 [2005]78 2005 rhu-pa 600,000.00 7 [2002]432 [2003]186 [2004]158 [2005]257 2002 2003 2004 2005 UPA 2,440,000.00 8 2005 400,000.00 9 863 2004 rhu-pa 2,400,000.00 10 [2001]1179 2,000,000.00 11 2005 1,000,000.00 12 2005 1,600,000.00 80

2005 32. 285,000,000.00 (1) + - [ [ 2] 1] % % 1 2 9,807,00 3.4-311,02-6,804,00-7,115,02 2,691,97 0.9 3 200,193,00 70.2-21,438,97 6,804,00-14,634,97 185,558,02 65.1 200,193,00 70.2-21,438,97 6,804,00-14,634,97 185,558,02 65.1 4 210,000,00 73.6-21,750,00-21,750,00 188,250,00 66.0 1 75,000,00 26.3 21,750,00 21,750,00 96,750,00 33.9 2 3 4 75,000,00 26.3 21,750,00 21,750,00 96,750,00 33.9 285,000,00 10 285,000,00 10 [ 1] 2005 11 2 680.40 [2005]1513 2005 12 22 [ 2] 2005 12 19 10 2.9 21,750,000 A 2005 12 28 2005 12 30 (2) 150,462,846 36 15,463,393 12 24 5% 81

2005 10,219,286 12 9,412,500 12 2,691,975 188,250,000 12 33. 566,689,203.37 (1) 566,256,803.91 566,256,803.91 391,352.10 41,047.36 432,399.46 566,648,156.01 41,047.36 566,689,203.37 (2) 1 1,598.92 2 23,011.59 3 16,436.85 34. 118,044,533.52 (1) 59,342,659.02 19,353,696.66 78,696,355.68 29,671,329.51 9,676,848.33 39,348,177.84 89,013,988.53 29,030,544.99 118,044,533.52 (2) 35 2 1 82

2005 35. 338,580,979.88 (1) 259,597,325.19 193,514,199.68 114,530,544.99 338,580,979.88 (2) 1) 2005 1 30 2005 2004 2004 28,500 10 3.00 85,500,000.00 2006 2 18 2005 2005 10% 5% 19,353,696.66 9,676,848.33 2) 8,550.00 2006 2 18 2005 10 3.00 8,550.00 ( ) 1 / 1,465,866,925.04/674,201,294.91 (1) 1,132,561,461.71 1,073,725,922.04 313,418,169.04 207,743,274.86 14,772,236.15 14,634,317.52 5,115,058.14 5,737,739.11 1,465,866,925.04 1,301,841,253.53 369,568,585.00 295,077,991.54 285,507,845.17 194,834,724.36 13,923,143.61 14,189,513.33 5,201,721.13 5,137,522.00 674,201,294.91 509,239,751.23 83

2005 (2) 1,325,724,560.41 1,204,874,887.95 209,373,672.10 167,147,039.30 167,719,360.90 133,072,639.71 65,079,172.94 44,778,715.03 21,827,731.12 16,371,826.37 14,742,470.29 9,407,628.31 6,636,843.40 156,721.67 508,455.16 1,838,611,657.73 1,548,810,066.93 372,744,732.69 246,968,813.40 1,465,866,925.04 1,301,841,253.53 533,994,557.67 422,842,556.61 201,256,944.32 158,934,158.77 164,200,589.11 128,969,596.73 63,475,415.95 43,530,172.54 20,926,406.91 11,247,414.40 10,827,964.56 7,151,315.40 5,348,383.03 103,495.80 231,193.38 1,024,959,905.19 748,080,259.99 350,758,610.28 238,840,508.76 674,201,294.91 509,239,751.23 (3) 5 386,057,555.90 26.34% 2 84 19,230,925.50 1,903,413.82 880,956.02 5% 12,079,914.34 11,208,111.05 7%

2005 5,247,597.34 4,815,544.44 3% 1% 19,230,925.50 16,904,611.51 3. 44,046,607.51 45,858,986.91 [ ] 26,322,846.76 4,147,234.30 4,669,317.50 1,956,573.38 18,000.26 18.61 8,979.46 378,300.13 1,009,214.92 44,046,607.51 22,671,764.98 [ ] 2005 15 300,000.00 4. 1,201,552.64 [ ] 638,331.56 45,733.33-397,132.57 557,678.22 712.88-292,007.36-1,443,464.51-970,432.37-1,201,552.64-659,028.18 [ ] 5. 1,100,000.00 50,000.00 GAP 1,100,000.00[ ] 1,100,000.00 50,000.00 [ ] [2005]1 GAP [2003]5 85

2005 ( ) 1. 3 15,689,455.68 15,689,455.68 2. 138,622,527.54 33,659,668.50 53,415,326.19 28,216,576.24 41,296,502.21 295,210,600.68 3. 4,147,234.30 4,147,234.30 4. 3 5,052,250.00 5,052,250.00 5. [ ] 176,000,000.00 176,000,000.00 [ ] 100,000,000.00 76,000,000.00 86

2005 6. 3 [ ] 25,421,166.67 25,421,166.67 [ ] 5 176,000,000.00 1,921,166.67 3 23,500,000.00 7. 2005 531,915,312.62 565,517,562.62 33,602,250.00 3 28,550,000.00 3 5,052,250.00 8 2005 374,952,963.27 390,642,418.95 15,689,455.68 3 15,689,455.68 ( ) 1. 310,969,514.50 (1) (%) (%) 1 326,990,792.78 99.88 16,349,539.64 310,641,253.14 204,206,234.62 99.84 10,210,311.73 193,995,922.89 1-2 78,354.05 0.02 7,835.41 70,518.64 322,178.40 0.16 32,217.84 289,960.56 2-3 322,178.40 0.10 64,435.68 257,742.72 327,391,325.23 100.00 16,421,810.73 310,969,514.50 204,528,413.02 100.00 10,242,529.57 194,285,883.45 (2) 5 327,391,325.23 100.00% 87

2005 (3) 5% 5% 2. 26,951,879.71 (1) (%) (%) 1 25,614,861.17 89.77 1,280,743.06 24,334,118.11 95,740,831.89 97.83 4,787,041.60 90,953,790.29 1-2 2,820,567.51 9.88 282,056.75 2,538,510.76 1,038,111.71 1.06 103,811.17 934,300.54 2-3 97,501.05 0.34 19,500.21 78,000.84 1,024,230.62 1.05 204,846.12 819,384.50 3-5 2,500.00 0.01 1,250.00 1,250.00 62,129.50 0.06 31,064.75 31,064.75 28,535,429.73 100.00 1,583,550.02 26,951,879.71 97,865,303.72 100.00 5,126,763.64 92,738,540.08 (2) (3) 5 3,953,773.41 13.86% (4) 5% 5% 3. 784,167,810.08 (1) 647,857,396.51 647,857,396.51 534,923,265.20 534,923,265.20 135,257,781.57 135,257,781.57 126,295,046.73 126,295,046.73 1,052,632.00 1,052,632.00 1,052,632.00 1,052,632.00 784,167,810.08 784,167,810.08 662,270,943.93 662,270,943.93 88

2005 (2) 1) a. 70.00 57,295,512.23 15,637,397.53 23,011.59-1,331,395.48 71,624,525.87 85.48 20 54,928,695.09 2,255,192.60 57,183,887.69 86.67 20 6,451,603.59 182,598.98 1,762,589.27 8,396,791.84 31.00 20 1,006,416.51 70,061.50 182,428.84 1,258,906.85 84.73 20 157,445,962.13 13,677,722.15 25,389.97 171,149,074.25 90.00 30 90,000,000.00 90,000,000.00 75.00 20 36,000,000.00-3,026,948.67 32,973,051.33 75.00 20 750,000.00-654,193.99 95,806.01 20.00 10 100,000.00-42,611.53 57,388.47 70.00 20 700,000.00-57,422.55 642,577.45 60.00 117,540,000.00 117,540,000.00 10.00 686,436.85 686,436.85 55.00 20 100,000,000.00-3,752,649.02 1,598.92 96,248,949.90 50.00 17 13,647,992.94-1,332,532.08 1,853,652.75 14,169,113.61 29.27 20 120,126,896.14 961,771.82 121,088,667.96 756,679,515.48 23,918,386.74 50,000.48 2,467,275.38 783,115,178.08 89

2005 b. 64,789,832.86 6,545,402.31 23,011.59 266,279.11 71,624,525.87 56,197,800.67 986,087.02 57,183,887.69 7,272,452.77 1,438,239.60-313,900.53 8,396,791.84 1,335,567.38 38,557.69-115,218.22 1,258,906.85 162,317,540.70 8,831,533.55 171,149,074.25 90,000,000.00 90,000,000.00 34,059,469.21-1,086,417.88 32,973,051.33 609,801.28-513,995.27 95,806.01 100,800.33-43,411.86 57,388.47 700,000.00-57,422.55 642,577.45 117,540,000.00 117,540,000.00 686,436.85 686,436.85 100,000,000.00-3,752,649.02 1,598.92 96,248,949.90 16,295,046.73-1,358,904.39-767,028.73 14,169,113.61 110,000,000.00 10,126,896.14 961,771.82 121,088,667.96 661,218,311.93 110,813,332.99 11,988,791.02 24,610.51-929,868.37 783,115,178.08 90

2005 2) a. -2,662,791.13-1,597,674.59-266,279.11-1,331,395.48 10 3,139,005.26 2,076,489.80 313,900.53 1,762,589.27 10 528,083.49 297,647.06 115,218.22 182,428.84 5 3,835,143.63 2,620,681.48 767,028.73 1,853,652.75 5 473,103.86 473,103.86 473,103.86 5,312,545.11 3,397,143.75 473,103.86 1,402,972.23 2,467,275.38 b. (3) 5% 1,052,632.00 1,052,632.00 1,052,632.00 1,052,632.00 (4) 91

2005 ( ) 1. 1,045,607,076.53 (1) 1,015,561,857.57 972,312,848.31 29,716,171.95 10,023,994.93 329,047.01 1,045,607,076.53 982,336,843.24 (2) 5 1,045,607,076.53 100% 2. 392,791,500.56 384,148,502.95 305,363,613.23 7,926,674.89 3,494,848.74 716,322.72 392,791,500.56 308,858,461.97 3. 13,109,342.76 [ ] 2,523,523.97 11,988,791.02 9,773,971.49-1,402,972.23-901,300.85 13,109,342.76 8,872,670.64 [ ] 92

2005 ( ) 1 (1) " 12 93

2005 12 : 555 2901- ; : 2904, 88 1-103- ; 2 (2) 35,000,000.00 35,000,000.00 186,000,000.00 41,880,000.00 227,880,000.00 79,000,000.00 79,000,000.00 64,066,000.00 64,066,000.00 9,000,000.00 9,000,000.00 3,000,000.00 3,000,000.00 185,390,000.00 185,390,000.00 100,000,000.00 100,000,000.00 48,000,000.00 48,000,000.00 1,000,000.00 1,000,000.00 500,000.00 500,000.00 94

2005 1,000,000.00 1,000,000.00 195,900,000.00 195,900,000.00 6,700,000.00 6,700,000.00 183,000,000.00 183,000,000.00 (3) % % % % 25,443,000.00 8.93 15,223,714.00 5.34 10,219,286.00 3.59 [ 1] 147,000,000.00 51.58 20,847,000.00 7.31 17,384,154.00 6.10 150,462,846.00 52.79 55,300,000.00 70.00 55,300,000.00 70.00 54,766,300.00 85.48 54,766,300.00 85.48 8,816,400.00 97.96 8,816,400.00 97.96 2,379,000.00 79.30 2,379,000.00 79.30 157,080,000.00 84.73 157,080,000.00 84.73 90,000,000.00 90.00 90,000,000.00 90.00 36,000,000.00 75.00 36,000,000.000 75.00 750,000.00 75.00 750,000.00 75.00 438,900.00 87.78 438,900.00 87.78 700,000.00 70.00 700,000.00 70.00 117,540,000.00 60.00 117,540,000.0 60.00 3,283,000.00 49.00 1,608,000.00 24.00 4,891,000.00 73.00 100,000,000.00 55.00 100,000,000.00 55.00 95

2005 [ 1] 2005 12 31 3.59% 60% 2 [ 1] [ 2] [ 3] [ 4] [ 1]: [ 2]: [ 3]: [ 4] 2005 3 7 Fulldragon Limited 2005 4 7 96

2005 ( ) 1. 25,530,676.91 41,612,429.17 52,105,353.71 54,256,296.76 6,749,322.71 5,645,457.76 1,593,476.93 84,385,353.33 103,107,660.62 2. 41,840.23 5,037,295.20 3,444,294.54 3,418.72 31,799.83-735,947.65[ ] 1,802,525.17 2,279.15 256,476.00 1,250,000.00 701,346.00 6,551,009.78 5,284,317.41 [ ] 3. ( ) ( ) ( ) ( ) % (1) 108,996.20 0.05 48,017.00 0.02 682,525.62 547,994.80 0.24 0.24 3,999.90 0.00 1,330.00 0.00 8,646.12 1,759,922.89 0.00 0.76 256,476.00 0.09 1,250,000.00 0.44 701,346.00 0.25 2,947,010.74 2,422,243.79 1.04 1.05 97

2005 (2) 30,000,000.00 14.05 3,800,000.00 3,997,119.95 2.59 1.87 18,600.00 0.01 [ ] 52,344,600.00 24.51 3,800,000.00 86,360,319.95 2.59 40.44 (3) 22,307.75 0.07 22,307.75 0.07 (4) 18,455,676.91 66,301,158.49 7.56 53.05 45,551,589.19 31,833,286.58 18.65 25.47 1,947,120.81 1.56 1,201,942.26 0.49 637,624.52 0.26 100,081,565.8 26.96 80.08 65,846,832.88 8 (5) 13,532.61 0.04 3,542,595.10 955,903.85 3.03 2.48 580,000.00 1.50 289,965.33 0.75 721,836.00 0.62 4,264,431.10 1,839,401.79 3.65 4.77 (6) 20,000,000.00 9,093,089.72 45.75 22.39 85,000.00 0.21 80,569.37 0.20 20,000,000.00 9,258,659.09 45.75 22.80 [ ] 2005 12 31 4. 1 2002 7 350.00 100.00 2005 6 330.00 98

2005 100.00 230.00 30.00 2 1 15,096,309.44 13,034,737.69 2 1,894,898.00 1,300,000.00 3 1,085,550.57 10,544,243.55 4) 337,344.00 0.00 (3) 1 966,000.00 1,480,000.00 2, 1,200,000.00 1,600,000.000 3, 3% 1,529,984.00 906,583.83 (4) 2005 1 1 2005 12 31 73,355.48 880,265.76 880,265.76 99

2005 (5) 1) 2005 1,000.00 1,000.00 2007.09.27 8,000 2,000.00 2,000.00 2008.10.08 3,000.00 3,000.00 2009.09.29 2,000.00 2,000.00 2010.9.29 1,000.00 1,000.00 2007.05.30 2,000.00 2,000.00 2008.05.30 11,000.00 11,000.00 2) a. 2005 3,000.00 2,000.00 5,000.00 5,000.00 3,600.00 2,000.00 2,000.00 2008.09.08 200.00 200.00 2006.07.08 100

2005 300.00 300.00 2006.10.09 600 200.00 200.00 2006.09.05 1,000.00 1,000.00 2006.12.05 1,000.00 1,000.00 1,000.00 2006.05.16 5,000 1,000.00 1,000.00 2007.05.16 1,000.00 1,000.00 2008.05.16 1,000.00 1,000.00 2009.05.16 1,000.00 1,000.00 2010.05.15 10,000.00 4,000.00 2006.6.22 38,300.00 12,700.00 10,500 b 2005 1,200.00 1,044.00 1,044.00 2006.06.28 1,500.00 1,350.00 1,350.00 2006.03.16 1,000.00 1,000.00 1,000.00 2006.03.28 1,000.00 1,000.00 1,000.00 2006.03.28 1,000.00 1,000.00 1,000.00 2006.03.28 1,000.00 1,000.00 1,000.00 2006.04.28 1,000.00 1,000.00 1,000.00 2006.04.28 101

2005 1,000.00 1,000.00 1,000.00 2006.04.28 1,000.00 1,000.00 1,000.00 2006.05.28 1,000.00 1,000.00 1,000.00 2006.05.28 1,000.00 1,000.00 1,000.00 2006.06.07 1,000.00 1,000.00 1,000.00 2006.06.07 53.076 53.076 53.076 2006.06.28 1,000 189.29344 189.29344 189.29344 2006.06.19 632.79174 632.79174 1,000.00 1,000.00 14,575.16 14,269.16 12,636.37 (6) 2004 16 9 230.00 60 1 35 1 30 4 5 3 2005 16 2005 [ ] 600,000.00 929,389.31 1,529,389.31 350,000.00 545,376.04 895,376.04-545,376.04 545,376.04-545,376.04 545,376.04-545,376.04 545,376.04-545,376.04 545,376.04 50,000.00 175,690.33 225,690.33 50,000.00 175,690.33 225,690.33 50,000.00 105,422.82 155,422.82-545,376.04 545,376.04-175,690.33 175,690.33-105,422.82 105,422.82 300,000.00 175,690.33 475,690.33 300,000.00 105,422.82 405,422.82 300,000.00 90,525.98 390,525.98 300,000.00 300,000.00 2,300,000.00 5,311,201.31 7,611,201.31 102

2005 [ ] 26 3 [ ] 2002-2004 2005 12 31 8 80,000,000.00 1 2005 5,095,850.00 4,182,843.54 6,000,000.00 3,000,000.00 2006.8.5 5,095,850.00 4,182,843.54 6,000,000.00 3,000,000.00 2 ( )4(5)1 3. 2005 12 31 11 000.00 8.41 % 70% 50% 2004 10 23 6,000.00 2004 12 31 131,189,985.31 Tasly America Pharmaceutical,Inc 100.00 2005 12 2006 1, 100.00 103

2005 ( ) ( ) ( ) ( ) 1 2004 7 31 2004 2004 9 4 2005 9 3 2005 8 6 2004 2006 9 3 2. 2006 2 18 3 1,660.00 2005 11 21 2006 5 21 2005 11 23 4 1 ---- 2004 + - 104 2005 712.88 300,000.00 1,400,000.00 460,012.06 2,523,523.97 638,331.56-457,574.54-651,650.37-1,500,000.00-1,500,000.00 1,325,961.49-112,605.93-266,646.34 183,150.30[ ] [ ] - 225,893.09 1,059,315.15-521,649.32

2005 2006 2 18 105