600488 2005
2005 1... 3 2... 3 3... 4 4... 5 5... 10 6... 15 7... 17 8... 20 9... 38 10... 41 11... 44 12... 81 2
2005 1 1.1 1.2 1.3 2 2.1 Tianjin Tianyao Pharmaceutical Co., Ltd. TJPC 2.2 2.3 109 022-24160861 022-24160910 E-mailtjpc600488@vip.sina.com 109 022-24160800-1011 022-24160910 E-mailtjpc600488@vip.sina.com 2.4 B 109 300171 http://www.tygf-jy.com tjpc600488@vip.sina.com 2.5 http://www.sse.com.cn 3
2005 2.6 A A G A 600488 2.7 1999 12 1 B 2005 63 B 1200001190408 12011771824811x 33 6-10 3 3.1 : : 95,006,995.32 80,803,526.36 81,015,897.79 181,137,191.31 1,224,854.94 95,270,792.81-35,813.72 50,000.00-277,983.77-108,866,094.02-14,788,612.19 3.2 : : -326,322.10 45,000.00 44,858.14 84,463.25-60,370.72-212,371.43 4
2005 3.3 : : 2005 2004 2003 (%) 661,330,551.50 964,176,260.27-31.41 668,081,863.10 95,006,995.32 122,103,166.81-22.19 106,914,771.74 80,803,526.36 100,858,183.01-19.88 90,075,722.98 81,015,897.79 91,581,457.66-11.54 76,669,579.83 0.321 0.401-19.95 0.358 % 8.11 10.73 2.62 10.14 % 8.40 11.03 2.63 10.68 1.61 8.13 9.74 % 8.63 1.59 8.43 10.02 % 9.09-108,866,094.02 110,300,224.18-198.70 45,770,868.02-0.432 0.438-198.63 0.182 2005 2004 2003 (%) 1,978,050,558.59 1,528,578,144.08 29.40 1,604,898,191.92 996,419,108.62 940,078,787.17 5.99 888,182,206.56 3.957 3.733 6.00 3.527 3.949 3.722 6.10 3.520 3.4 : : 251,825,012.00 415,824,646.52 53,018,447.55 21,863,066.25 197,547,614.85 940,078,787.17 4,049,296.29 8,256,634.81 4,108,964.82 68,437,926.73 84,852,822.65 3,330,000.00 25,182,501.20 28,512,501.20 251,825,012.00 416,543,942.81 61,275,082.36 25,972,031.07 240,803,040.38 996,419,108.62 1 2 3 4 2004 4 4.1 4.1.1 5
2005 : (%) (%) 1 2 175,775,012 69.80-28,899,000-28,899,000 146,876,012 58.32 3 4 175,775,012 69.80-28,899,000-28,899,000 146,876,012 58.32 1 76,050,000 30.20 28,899,000 28,899,000 104,949,000 41.68 2 3 4 76,050,000 30.20 28,899,000 28,899,000 104,949,000 41.68 251,825,012 100 251,825,012 100 2006-10-25 2007-10-25 2008-10-25 2009-10-25 : 5,648,596 141,227,416 110,597,596 25,182,501 25,182,501 116,044,915 135,780,097 10.10 15,314,910 15,314,910 100,730,005 151,095,007 10.10 100,730,005 0 251,825,012 100,730,005 10.10 2005 10 9 [2005]67 2005 10 13 6
2005 2005 10 24 2005 10 20 10 3.8 4.1.2 4.1.2.1 4.1.2.2 2005 10 13 10 3.8 2005 10 24 175,775,012 146,876,012 69.80% 58.32% 76,050,000 104,949,000 30.20% 41.68% 4.1.2.3 4.2 4.2.1 : 16,146 (%) 56.08 141,227,416-27,787,596 141,227,416 2.11 5,312,897 5,312,897 0 0.84 2,126,727-2,154,257 0 0.60 1,513,292-2,139,296 0 0.58 1,459,124 1,459,124 0 0.56 1,412,149-277,851 1,412,149 0.56 1,412,149-277,851 1,412,149 7
2005 0.56 1,412,149-277,851 1,412,149 0.56 1,412,149-277,851 1,412,149 0.49 1,237,576 340,782 0 5,312,897 2,126,727 1,513,292 1,459,124 1,237,576 1,000,000 524,400 483,000 417,344 393,332 10 51 4.2.2 : 141,227,416 2007-10-25 25,182,501 8
2005 2007-10-25 25,182,501 2008-10-25 15,314,910 2009-10-25 100,730,005 1,412,149 2006-10-25 1,412,149 1,412,149 2006-10-25 1,412,149 1,412,149 2006-10-25 1,412,149 1,412,149 2006-10-25 1,412,149 4.2.3 4.2.3.1 674,970,000 2000 8 8 4.2.3.2 841,920,000 2001 11 12 9
2005 4.2.3.3 4.2.3.4 4.2.4 5 5.1 : : ( ) 2005-11- 2008-11- 55 0 0 0 17.55 28 28 2005-11- 2008-11- 65 0 0 0 0 28 28 2005-11- 2008-11- 56 0 0 0 0 28 28 2005-11- 2008-11- 38 0 0 0 17.55 28 28 2005-11- 2008-11- 33 0 0 0 14.67 28 28 2005-11- 2008-11- 31 0 0 0 14.67 28 28 2005-11- 2008-03- 70 0 0 0 4.5 28 30 2005-11- 2008-03- 50 0 0 0 4.5 28 30 10
2005 44 2005-11- 2008-11- 28 28 0 0 0 4.5 2005-11- 2008-11- 51 28 28 0 0 0 14.67 33 2005-11- 2008-11- 28 28 0 0 0 0 33 2005-11- 2008-11- 28 28 0 0 0 0 31 2005-11- 2008-11- 28 28 0 0 0 0 29 2005-11- 2008-11- 28 28 0 0 0 6.5 2005-11- 2008-11- 57 28 28 0 0 0 14.67 39 2005-11- 2008-11- 28 28 0 0 0 14.67 45 2005-11- 2008-11- 28 28 0 0 0 14.67 48 2005-11- 2008-11- 28 28 0 0 0 12.56 / / / / / / 155.68 5 (1) (2) (3) (4) (5) 11
2005 (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) 12
2005 (16) (17) (18) 5.2 13
2005 5.3 5.3.1 5.3.2 2004 4.5 / 5.3.3 5.4 2005 11 28 2005 6 6 2005 11 28 2005 6 6 1 2 14
2005 2005 2005 11 28 2005 2005 11 28 5.5 1,510 187 1 1007 15 219 179 25 9 34 47 2 167 191 1,152 6 6.1 (1) 15
2005 (2) (3) (4) (5) (6) (7), (8)2005 10 13 99.4% 95.67%2005 10 24 6.2 6.2.1 16
2005 8 7 1 0 8 8 0 0 8 5 3 0 2005 6.2.2 6.3 (1) (2) (3) (4) (5) 6.4 2005 2 2 7 7.1 17
2005 2005 3 7 2004 2005 3 8 12004 22004 32004 42004 5 2005 6 2004 7 ( ) 8 9 10 11 7.2 7.2.1 2005 5 31 2005 2005 6 1 12,000 24,000 80 7.2.2 2005 7 15 2005 2005 7 16 1 A 2 18
2005 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 2.10 2.11 2.12 2.13 2.14 2.15 3 4 7.2.3 2005 11 28 2005 2005 11 29 1 2 7.3 2005 10 13 862 204,102,943 81.05% (1) 10 3.8 (2) 1 2 5 24 36 19
2005 10 12 40 2005 2005 10 14 8 8.1 8.1.1 8.1.1.1 2005 661,330,551.50 2004 302,845,708.77 2005 2004 4.16% 2005 80,803,526.36 2004 100,858,183.01 15,963,249.28 516 2004 1.06% 2005 28% 2005 2005 50% 20
2005 8.1.1.2 1 1 3029 3029 3029 3029 1000 2005 12 2007 300 2005 1673 42 100 2 GMP 21
2005 GMP 2005 2005 1 GMP 8 23 GMP 13 GMP 2005 TARO GMP 3 2005 2005 DMF EDMF 3.3 22
2005 2 1 2005 A. 2005 1 3.3 20 62 5.6 5.06% B. C. D. 2 23
2005 GMP SOP 6000 2 36 4 A. 2004 2005 6 B. 12 10 3.5 10 3.8 99.4 95.67 C. 2005 10 25 11 28 D. 2005 400 80% 682 2005 2005 24
2005 20.07% 2005 12 31 5000 3.33% 3.37% 3.25% 8.1.1.3 8.1.1.3.1 : : (%) % 0.94 596,588,099.60 423,395,666.07 28.71 4.47 5.88 2.09 61,834,894.90 55,619,277.08 9.73 5.18 2.96 8.1.1.3.2 : : () 200,694,624.74 24.74 156,876,747.17-60.99 30,452,446.97-48.60 273,306,732.62-20.07 661,330,551.50-31.41 329,247,060.52 114,717,987.71 (%) 21.73 317,250,032.37 (%) 47.97 8.1.1.4 (1) 6692 (2) 1612.72 25
2005 (3) 24650.2 (4) 9974.1 80 5059.67 2004 9 (5) 29,915.12 2004 (6) 970.13 8.1.1.5 2005 2004 : : -108,866,094.02 110,300,224.18-219,166,318.20-154,624,480.13-121,634,789.23-32,989,690.90 247,916,080.54-199,769,171.14 447,685,251.68 785,881.42-310,291.72 1,096,173.14-14,788,612.19-211,414,027.91 196,625,415.72 1-26
2005 2 3 4 14,788,612.19 196,625,415.72 8.1.1.6 : : 18000 33934.6 201.8 1804.055 3786.0 95.2 6400 7444.9 9.6 500 2546.5 1.2 500 4590.8-8.1.2 8.1.2.1 1300 80 22% 50% 27
2005 8.1.2.2 2006 3029 2005 80 3029 70% 2006 6.8 3029 2006 46 1000 2006 28
2005 2006 8.1.2.3 2006 6.8 8.1.2.4 8.1.2.4.1 2006 1 2004 2005 2 3 4 2006 8.1.2.4.2 2006 1 6% 2 29
2005 2006 3 50 80 3029 2006 6.8 4 8.2 8.2.1 22,160.71 8,116.57 57.79 (%) 2005 7 80.00 500 400 80% 1 150250 3.3% 2005 12 31 100100 50150 3.37 3.25 2 8550 23.39% 2005 11 7 20.07 30
2005 8.2.2 2001 49,214.79 48,473.29 4,283.31 741.5 8.2.2.1 : : 5 4,940 4,139.31 1,920 2,976 2,193.78 1,150 2,618 2,862.04 900 10 2,876 2,006.38 490 10 2,980 3,146.27 1,895 20 2,950 2,795.98 500 2,990 3,707.07 856 2,980 2,785 3,279.20 1,200 300 2,982 12000 2,895 24000 2,150 2,900 10,192.81 10,192.81 49,214.81 / 34,322.84 8,911 / / 34322.84 35307.81 984.97 1 10 5 5,267.47 4965 302.47 31
2005 2 856 1200 900 111.85 324.34 109.94 204.39 324.34 32.99 3 20 10 COS :42.33 189.51 8.2.2.2 2002 3 30 2001 300 2002 4 2 2005 5 31 2005 12000 24000 80 2005 6 1 2002 11 25 2002 30 32
2005 2002 11 26 : : 30 2,900 3,682.20 2,500 2,610.01 641.49 672.23 300 80 12000 24000 8,928.16 7,186.02 / 14,969.65 14,150.46 / / 1 80 2005 5 2005 5 31 3408.30 2126.35 2005 80 5,059.67 2005 12 31 7186.02 2 80 1 30 2.04 2 33
2005 22.91 57.89 3 4 80 63.14 8.2.2.3 (1) 500 4,123.58 (2) 8,698.92,, (3) RSA 8,628.57 (4) 2,578.95 (5) 895.22 (6) 3,917.93 8.3 8.3.1 8.3.1.1 2005 2 2 1 2004 2 2004 34
2005 3 2004 4 2004 5 2005 6 2004 7 ( ) 8 9 10 11 12 13 14 15 16 2004 2005 2 4 8.3.1.2 2005 4 20 2005 2005 4 22 8.3.1.3 2005 4 29 1 2 2005 2005 4 30 8.3.1.4 2005 6 6 1 2 2005 6 7 8.3.1.5 2005 6 14 1 6.8 A 35
2005 A A B 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 1.10 1.11 1.12 1.12.1 500 1.12.2 1.12.3 1.12.4 1.12.5 1.12.6 1.12.7 1.13 1.14 1.15 C 2 3 2005 2005 6 15 8.3.1.6 2005 7 27 1 2005 2 2005 7 29 8.3.1.7 2005 10 25 1 2005 2 3 4 2005 2005 10 27 8.3.1.8 2005 11 28 1 2 3 4) 5 36
2005 6 7 8 2005 11 29 8.3.2 (1) 2005 3 7 2004 2004 2005 5 17 (2) 2004 7 16 2004 6.8 A 2004 9 30 2005 3 2004 2005 7 15 2005 (3) 2005 10 13 2005 10 19 2005 10 20 2005 10 24 10 3.8 " "G " 8.4 2005 80,062,622.98 10 8,006,262.30 5 4,003,131.15 176,534,228.24 37
2005 244,587,457.77 2005 251,825,012 10 0.5 ( ) 12,591,250.6 231,996,207.17 2005 2005 251,825,012 10 8 2005 9 9.1 9.1.1 2005 2 2 12004 22004 32004 42004 5 2005 6 2004 7 ( ) 8 9 10 11 12 2005 2 4 9.1.2 2005 4 20 2005 2005 2005 4 22 38
2005 9.1.3 2005 4 29 2005 4 30 9.1.4 2005 6 14 1 6.8 A 1 A 2 3 2 2005 6 15 9.1.5 2005 7 27 1 2005 2 2005 7 29 9.1.6 2005 10 25 1 2005 2 2005 3 2005 10 27 39
2005 9.1.7 2005 11 28 1 2 3 2005 11 29 9.2 2005 9.3 2005 2005 9.4 2005 4 29 2005 5 31 2005 12,000 24,000 6.8 40
2005 9.5 10 10.1 10.2 10.3 10.3.1 (1) : : () 124,464.64 0.02 41,547,548.29 7.01 18,121,785.65 3.06 357,891.68 0.06 (2) : : () 18,016,575.13 2.72 9,471,487.37 41,515,952.96 6.28 9,929,875.67 9,330,769.28 1.41 1,082,822.42 41
2005 10,214,529.88 1.54 1,853,241.71 0.28 20,751,485.84 3.14 84,783,520.71 12.82 80,333.68 0.01 35,145.30 0.01 1,543,900.20 415,401.26 3,884,690.42 10,092,315.84 8,246.44 10,649.55 8478.35 12.82% 10.3.2 400 500 4,591 10.4 10.5 10.6 10.7 300 : : 300.00 300.00 42
2005 300.00 (%) 0.3 0 70 0 50% 0 300.00 10.8 10.9 10.10 1 2 5 24 36 10 12 40 10.11 10.12 10.13 43
2005 11 11.1 200610068 2005 12 31 2005 2005 2005 12 31 2005 2006 3 2 44
2005 11.2 2005 12 31 : : : 207,376,493.60 222,165,105.79 171,312,366.25 82,251,686.06 0.00 0.00 10,553,021.09 11,258,559.26 7,124,143.52 9,944,390.72 0.00 7,991,310.16 6,225,749.12 0.00 0.00 222,322,419.52 155,402,368.02 132,674,553.16 96,936,281.57 10,097,614.87 11,103,088.56 45,767,107.27 10,418,409.27 19,075,971.28 2,948,782.91 31,893,932.99 13,533,279.60 6,458,425.07 10,617,351.03 0.00 575,646,815.45 329,144,076.12 423,213,183.05 302,841,621.95 708,016.07 562,900.55 677,893.91 559,693.39 0.00 0.00 0.00 0.00 1,052,238,776. 95 743,202,232.24 820,654,490.31 522,711,111.68 82,156,605.49 77,947,599.68 313,458,438.98 305,184,020.90 0.00 0.00 82,156,605.49 77,947,599.68 313,458,438.98 305,184,020.90 ( - ) ( - ) 767,699,156.85 684,603,010.48 681,976,605.67 599,661,433.62 223,596,734.55 179,587,209.52 207,507,874.96 168,803,483.05 544,102,422.30 505,015,800.96 474,468,730.71 430,857,950.57 0.00 0.00 544,102,422.30 505,015,800.96 474,468,730.71 430,857,950.57 67,518,128.72 67,835,226.14 54,759,697.72 67,495,026.14 207,781,760.61 108,040,310.08 179,304,349.38 108,024,340.43 0.00 1,690,982.51 0.00 1,690,982.51 819,402,311.63 682,582,319.69 708,532,777.81 608,068,299.65 22,927,461.10 22,641,538.65 19,901,744.81 20,465,923.37 1,325,403.42 2,204,453.82 1,325,403.42 2,204,453.82 0.00 0.00 24,252,864.52 24,845,992.47 21,227,148.23 22,670,377.19 45
2005 1,978,050,558. 59 1,528,578,144.08 1,863,872,855.33 1,458,633,809.42 460,939,492.16 161,788,333.36 362,250,000.00 150,000,000.00 37,611,869.06 8,000,000.00 26,611,869.06 6,000,000.00 133,844,871.00 54,743,279.11 117,459,367.23 49,531,630.39 4,551,673.85 2,764,868.98 827,252.67 1,089,804.24 0.00 0.00 1,228,103.13 1,269,885.35 204,390.75 461,584.88 1,317,728.67 728,333.48 0.00-12,779,014.71 4,529,940.96 4,643,519.96 4,716,405.49 195,352.36 224,667.30 139,637.27 140,222.33 5,467,216.50 4,203,682.59 52,500,834.55 1,304,596.32 0.00 0.00 0.00 0.00 300,000,000.00 300,000,000.00 0.00 0.00 932,377,292.02 238,252,991.13 864,636,871.49 213,244,243.65 0.00 300,000,000.00 0.00 300,000,000.00 0.00 0.00 0.00 0.00 1,048,000.05 2,851,000.05 948,000.05 2,701,000.05 0.00 0.00 1,048,000.05 302,851,000.05 948,000.05 302,701,000.05 0.00 0.00 933,425,292.07 541,103,991.18 865,584,871.54 515,945,243.70 ( 48,206,157.90 47,395,365.73 ) 251,825,012.00 251,825,012.00 251,825,012.00 251,825,012.00 0.00 0.00 251,825,012.00 251,825,012.00 251,825,012.00 251,825,012.00 416,543,942.81 415,824,646.52 416,543,942.81 415,824,646.52 87,247,113.43 74,881,513.80 85,331,571.21 73,322,177.76 25,972,031.07 21,863,066.25 25,353,277.06 21,350,145.91 240,803,040.38 197,547,614.85 244,587,457.77 201,716,729.44 12,591,250.60 25,182,501.20 12,591,250.60 25,182,501.20 ( ) ( ) 996,419,108.62 940,078,787.17 998,287,983.79 942,688,565.72 1,978,050,558.59 1,528,578,144.08 1,863,872,855.33 1,458,633,809.42 : : : 46
2005 2005 1-12 : : : 661,330,551.50 964,176,260.27 849,554,937.71 1,026,668,820.99 478,060,838.60 774,305,950.80 703,396,677.88 866,532,108.85 2,132,521.59 3,167,997.78 1,926,141.25 2,964,490.21 181,137,191.31-186,702,311.69 144,232,118.58 157,172,221.93.28 1,224,854.94-924,362.64 7,283,137.23 582,642.93 : 9,435,806.37 8,261,060.29 1,923,396.18 1,608,143.02 52,195,988.73 52,447,912.20 37,817,212.40 39,687,857.00.29 25,459,458.34 15,758,205.51 20,643,427.67 15,216,681.31-95,270,792.81 111,159,496.33 91,131,219.56 101,242,183.53 -.30.5-35,813.72 10,858,957.75 2,343,923.23 17,831,886.72 50,000.00 406,419.00 0.00.31 162,297.64 432,802.07 146,192.64 420,481.60.32 440,281.41 754,508.34 436,283.70 700,898.15 95,006,995.32 122,103,166.81 93,185,051.73 118,793,653.70-13,505,439.48 20,421,286.86 13,122,428.75 16,073,814.16 698,029.48 823,696.94 ( ) - 80,803,526.36 100,858,183.01 80,062,622.98 102,719,839.54 197,547,614.85 163,624,950.98 201,716,729.44 164,769,868.23 0.00 278,351,141.21 264,483,133.99 281,779,352.42 267,489,707.77 8,217,929.63 11,033,294.48 8,006,262.30 10,271,983.95 4,108,964.82 5,516,647.25 4,003,131.15 5,135,991.98 ( ) 266,024,246.76 247,933,192.26 269,769,958.97 252,081,731.84 0.00 0.00 38,705.18 20,575.01 0.00 25,182,501.20 50,365,002.40 25,182,501.20 50,365,002.40 0.00 0.00 ( - ) 1. 2. 3. ( ) 240,803,040.38 197,547,614.85 244,587,457.77 201,716,729.44 47
2005 4. ( ) 5. 6. : : : 2005 1-12 : : : 599,963,736.97 469,333,992.20 37,422,142.85.33 4,118,476.14 51,820,387.86 641,504,355.96 521,154,380.06 612,290,229.12 334,083,082.48 67,587,157.25 52,292,266.99 39,957,850.48 34,522,406.77.34 30,535,213.13 16,222,177.78 750,370,449.98 437,119,934.02-108,866,094.02 84,034,446.04 353,240.40 1,562,689.86 1,431,689.86 1,562,689.86 1,784,930.26 156,187,169.99 155,354,894.16 4,000,000.00 156,187,169.99 159,354,894.16-154,624,480.13-157,569,963.90 1,000,000.00 1,000,000.00 1,071,419,654.94 732,250,000.00 1,072,419,654.94 732,250,000.00 772,268,496.14 520,000,000.00 49,905,078.26 47,323,801.95 2,330,000.00 2,330,000.00 824,503,574.40 569,653,801.95 247,916,080.54 162,596,198.05 48
2005 785,881.42-14,788,612.19 89,060,680.19 1 80,803,526.36 80,062,622.98 ( - ) 698,029.48-99,804.27-29,282.97 44,379,213.60 38,996,915.86 4,672,432.84 5,714,178.56 1,217,103.20 1,217,103.20-145,115.52-118,200.52 326,117.65 324,083.70 (: ) 1,163.76 23,660,578.32 22,141,300.75 35,813.72-2,343,923.23-246,502,739.33-120,354,320.94 ( ) -45,545,039.49-78,417,828.69 ( ) 27,632,625.66 136,841,797.34 ( ) -108,866,094.02 84,034,446.04 2 3 207,376,493.60 171,312,366.25 222,165,105.79 82,251,686.06-14,788,612.19 89,060,680.19 : : : 49
2005 2005 : : : 1 636,831.44 / / 82,564.11 554,267.33 2 600,793.96 / / 57,452.69 543,341.27 3 36,037.48 / / 25,111.42 10,926.06 4 5 6 7 736,291.37 14,070.68 31,310.84 31,310.84 719,051.21 8 643,240.45 19,698.41 19,698.41 623,542.04 9 71,484.70 14,042.60 85,527.30 8.37 28.08 36.45 3,418.07 974.65 974.65 2,443.42 18,139.78 10,637.78 10,637.78 7,502.00 10 11 12 13 14 15 16 17 18 19 20 21 : : : 9 : : % 18.18 18.84 0.719 0.719 9.56 9.91 0.378 0.378 8.11 8.40 0.321 0.321 8.13 8.43 0.322 0.322 50
2005 19999 1999 12 1 [2001]29 2001 5 24 45,000,000 149,008,883 2002 4 2001 2001 149,008,883 10 2 10 1 10 2 193,711,548 2003 4 3 2003 58,113,464 251,825,012 2005 10 13 10 3.8 2005 10 24 1 2 1 1 12 31 3 4 5 6 1 (1 ) 51
2005 1 1 2 3 4 2 3 4 7 1 1 2 2 3 3 2 5% 2 5 10% 5 100% 8 1 2 3 52
2005 9 1 1 ( ) 2 3 20% 20%20% 20%20% 20% 50% 50% 10 2 3 10 53
2005 11 1 2 3, 1 1545 2.13%6.4% 812 8%12% 1118 5.33%8.73% 714 6.86%13.71% 714 6.86%13.71% 714 6.86%13.71% 612 8%16% 8 12% 12,, 13 2 3 54
2005 14 1 2 15, 16 17 1 2 3 18 19 1 2 20 21 199511 962 2005 1-12 50% 50% 50% 55
2005 1 17% 2 5% 3 7%3%1% 4 15% 1,804.055 920.068 51% 18,000 16,200 90% 6,400 4,480 70% 500 460 92% 500 400 80% 1 107,946.17 37,713.22 203,968,547.43 220,353,387.60 3,300,000.00 1,774,004.97 207,376,493.60 222,165,105.79 1 56
2005 2 2 10,103,021.09 11,258,559.26 450,000.00 0.00 10,553,021.09 11,258,559.26 3 1 % 3 213,191,838.26 95.66 0.00 213,191,838.26 3 2 8,648,419.74 3.88 432,420.99 8,215,998.75 25 1,016,202.79 0.46 101,620.28 914,582.51 5 9,300.00 0.00 9,300.00 0.00 222,865,760.79 100.00 543,341.27 222,322,419.52 % 3 144,411,515.86 92.57 0.00 144,411,515.86 3 2 11,167,412.84 7.16 558,370.64 10,609,042.20 25 424,233.28 0.27 42,423.32 381,809.96 5 0.00 0.00 0.00 0.00 156,003,161.98 100.00 600,793.96 155,402,368.02 124,628,458.22 55.92% 9,651,962.31 2 (%) 3 9,911,819.79 98.05 0.00 9,911,819.79 3 2 174,921.14 1.73 8,746.06 166,175.08 25 21,800.00 0.22 2,180.00 19,620.00 5 0.00 0.00 0.00 0.00 10,108,540.93 100.00 10,926.06 10,097,614.87 57
2005 (%) 3 10,479,854.84 94.08 0.00 10,479,854.84 3 2 597,792.95 5.37 29,889.65 567,903.30 25 61,478.25 0.55 6,147.83 55,330.42 5 0.00 0.00 0.00 0.00 11,139,126.04 100.00 36,037.48 11,103,088.56 6,991,587.66 69.17% 5% 5% 4 % % 1 19,030,235.18 99.76 2,948,782.91 100 1-2 45,736.10 0.24 0.00 0.00 2-3 0.00 0.00 0.00 0.00 3 0.00 0.00 0.00 0.00 19,075,971.28 100.00 2,948,782.91 100.00 5% 5% 5 6,458,425.07 10,617,351.03 6 186,891,527.08 85,527.30 55,627,101.22 71,484.70 55,006.74 36.45 66,102.33 8.37 1,710,342.46 2,443.42 716,167.26 3,418.07 50,868.18 0.00 644,321.89 0.00 58
2005 2,727,518.53 7,502.00 3,332,168.56 18,139.78 21,101,834.53 0.00 24,362,929.84 0.00 8,605,691.93 0.00 7,227,008.89 0.00 293,851,489.56 0.00 204,240,806.30 0.00 61,371,587.65 623,542.04 33,663,761.20 643,240.45 576,365,866.66 719,051.21 329,880,367.49 736,291.37 7 562,900.55 868,777.84 723,662.32 708,016.07 0.00 3,289,210.38 3,289,210.38 0.00 562,900.55 4,157,988.22 4,012,872.70 708,016.07 8 2000.10-2020.10 8.6% 386,784.29 0.00 386,784.29 0.00 2001.11 7% 5,925,000.00 0.00 5,925,000.00 0.00 2001.11 3.3% 50,000,000.00 0.00 50,000,000.00 0.00 2000.10.16 16.67% 62,488.98 0.00 62,488.98 0.00 2002.12 20.07% 25,782,332.22 0.00 21,573,326.41 0.00 82,156,605.49 0.00 77,947,599.68 0.00 20,000,000.00 0.00 4,209,005.81 0.00 5,782,332.22 20,000,000.00 0.00 4,209,005.81 0.00 5,782,332.22 2005 042 23.39% 20.07% 59
2005 9 302,292,095.31 28,354,803.01 357,315.00 330,289,583.32 36,421,519.42 834,995.65 0.00 37,256,515.07 20,600,565.35 1,842,890.56 0.00 22,443,455.91 99,850,470.49 13,221,351.40 0.00 113,071,821.89 164,411,739.59 35,944,627.12 0.00 200,356,366.71 6,471,641.89 210,500.00 181,008.33 6,501,133.56 44,411,739.07 3,169,665.96 29,094.00 47,552,311.03 10,143,239.36 84,730.00 0.00 10,227,969.36 684,603,010.48 83,663,563.70 567,417.33 767,699,156.85 50,400,543.90 12,337,387.90 292,523.95 62,445,407.85 7,366,818.76 3,804,939.01 0.00 11,171,757.77 9,035,474.57 1,762,034.66 0.00 10,797,509.23 32,916,778.28 7,893,181.17 0.00 40,809,959.45 48,697,564.92 13,817,615.39 0.00 62,515,180.31 2,629,036.30 580,731.66 49,234.38 3,160,533.58 21,155,563.98 3,114,810.48 27,930.24 24,242,444.22 7,385,428.81 1,068,513.33 0.00 8,453,942.14 179,587,209.52 44,379,213.60 369,688.57 223,596,734.55 505,015,800.96 544,102,422.30 1 83,187,656.70 3 2005 12 31 10 2,000,000.00 1,650,527.25 0.00 1,650,527.25 85% 2,000,000.00 1,706,603.90 0.00 1,706,603.90 97% 3,600,000.00 2,190,962.64 0.00 2,190,962.64 97% 6,000,000.00 5,492,672.55 0.00 5,492,672.55 95% 60
2005 1,000,000.00 807,976.04 0.00 807,976.04 95% FDA 380,000.00 1,072,746.41 2,405.01 1,075,151.42 97% 350,000.00 321,876.56 0.00 321,876.56 95% 100,000.00 131,612.43 0.00 131,612.43 80% 102103 3,000,000.00 2,550,242.50 2,038,863.00 4,589,105.50 97% 101 1,107,500.00 1,024,550.46 0.00 1,024,550.46 90% 11,000,000.00 12,019,403.18 0.00 12,019,403.18 90% 10,000,000.00 0.00 3,782,141.70 3,782,141.70 30% 11,000,000.00 6,627,240.96 2,324,956.63 8,952,197.59 97% 11,000,000.00 4,150.00 0.00 4,150.00 0% 2,700,000.00 1,830,610.33 41,742.06 1,872,352.39 80% 50,000,000.00 25,982,416.21 20,916,350.69 46,601,539.10 297,227.80 0.00 100 % 25,000,000.00 6,727,432.70 16,477,457.37 23,204,890.07 0.00 100 % 100 15,000,000.00 2,870.00 10,124,376.12 10,127,246.12 0.00 % 100,000,000.00 14,785,937.20 32,203,228.20 46,989,165.40 50% 23,000,000.00 7,706,724.74 14,538,044.61 22,244,769.35 70% 1,374,000.00 1,575,287.20 0.00 1,575,287.20 95% 104 30,000.00 29,200.00 0.00 29,200.00 97% 201 2,200,000.00 1,801,997.43 0.00 1,801,997.43 92% 2,000,000.00 1,636,466.46 0.00 1,636,466.46 97% 3,500,000.00 1,115,213.00 2,140,752.91 3,255,965.91 95% 105 7,000,000.00 2,266,052.96 1,314,787.00 3,580,839.96 97% 106 R.S.A 15,000,000.00 1,374,364.73 4,164,655.49 5,539,020.22 60% 35,000,000.00 3,920,052.26 13,519,307.92 17,439,360.18 60% α 5,000,000.00 793,641.32 4,248,853.09 5,042,494.41 60% 3028 25,000,000.00 31,155.00 16,630,933.79 16,662,088.79 70% 104 3,500,000.00 0.00 2,702,751.62 2,702,751.62 70% 3029 458,000,000.00 0.00 28,477,411.23 28,477,411.23 10% 860,323.66 7,601,703.59 3,253,981.41 24,387.00 5,183,658.84 108,040,310.08 183,250,722.03 83,187,656.70 321,614.80 207,781,760.61 1 149,306.85 5.35 2 2005 12 31 61
2005 11 24,020,000.00 10,608,833.13 2,402,000.04 15,813,166.91 8,206,833.09 41 1,302,093.20 748,703.42 130,209.36 683,599.14 618,494.06 57 273,777.99 203,052.11 11,407.40 82,133.28 191,644.71 0.00 0.00 5,077,058.00 4,019,337.50 507,705.84 1,565,426.34 3,511,631.66 83 351,000.00 301,275.00 35,100.00 84,825.00 266,175.00 91 2,050,000.00 1,991,916.61 41,000.04 99,083.43 1,950,916.57 571 3,105,209.60 2,684,715.76 65,337.12 485,830.96 2,619,378.64 508 7,380,685.61 2,083,705.12 5,150,000.00 1,479,673.04 1,626,653.53 5,754,032.08 43,559,824.40 22,641,538.65 5,150,000.00 4,672,432.84 20,440,718.59 191,644.71 22,927,461.10 1 2 2005 12 31 12 1,351,852.30 697,716.43 40,825.00 432,844.99 1,046,155.86 305,696.44 2,043,729.47 1,506,737.39 297,227.80 784,258.21 1,024,022.49 1,019,706.98 3,395,581.77 2,204,453.82 338,052.80 1,217,103.20 2,070,178.35 1,325,403.42 13 350,000,000.00 150,000,000.00 8,400,000.00 4,788,333.36 102,539,492.16 7,000,000.00 460,939,492.16 161,788,333.36 1 3,000,000.00 62
2005 2 32,250,000.00 37,289,492.16 30,000,000.00 3 8,400,000.00 14 16,000,000.00 2,000,000.00 21,611,869.06 6,000,000.00 37,611,869.06 8,000,000.00 20,401,869.06 15 1 133,844,871.00 54,743,279.11 2 4,551,673.85 2,764,868.98 3 5,467,216.50 4,203,682.59 2003 300,000.00 5% 5% 3 1 16 1,317,728.67 728,333.48 17-13,517,094.30 3,625,505.15 43,879.03 16,605.90 63
2005 243,620.95 358,442.32 319,894.34 272,746.81 4,112.84 63,292.24 108,453.01 173,314.51 2,203.09 4,117.70 15,916.33 15,916.33-12,779,014.71 4,529,940.96 18 137,097.60 137,233.22 57,159.85 61,910.68 0.05 25,523.40 1,094.86 0.00 195,352.36 224,667.30 19 300,000,000.00 0.00 2006 5 28 20 300,000,000.00 2006 5 28 21 1,048,000.05 2,851,000.05 22 1 175,775,012.00-28,899,000.00-28,899,000.00 146,876,012.00 2 64
2005 3 4 175,775,012.00-28,899,000.00-28,899,000.00 146,876,012.00 1 76,050,000.00 28,899,000.00 28,899,000.00 104,949,000.00 2 3 4 76,050,000.00 28,899,000.00 28,899,000.00 104,949,000.00 251,825,012.00 251,825,012.00 2005 10 13 10 3.8 28,899,000 175,775,012 146,876,012 69.80% 58.32% 76,050,000 104,949,000 30.20% 41.68% 23 414,416,818.45 3,330,000.00 411,086,818.45 0.00 0.00 1,403,400.00 4,049,296.29 5,452,696.29 0.00 0.00 0.00 1 2 4,428.07 4,428.07 415,824,646.52 4,049,296.29 3,330,000.00 416,543,942.81 8 24 43,726,132.51 8,217,929.63 0.00 51,944,062.14 9,292,315.04 38,705.18 0.00 9,331,020.22 21,863,066.25 4,108,964.82 0.00 25,972,031.07 74,881,513.80 12,365,599.63 0.00 87,247,113.43 65
2005 1 2005 10% 8,006,262.30 2005 5% 4,003,131.15 2005 10% 211,667.33 2005 5% 105,833.67 2 2004 2005 5% 38,705.18 25 197,547,614.85 80,803,526.36 8,217,929.63 4,108,964.82 38,705.18 25,182,501.20 0.00 240,803,040.38 12,591,250.60 1 2004 2004 251,825,012 10 1 25,182,501.20 2 2005 251,825,012 10 0.5 12,591,250.60 26 1 596,588,099.60 571,082,298.78 423,395,666.07 399,879,645.19 1,747,777.35 1,182,105.86 620,694.75 329,852.65 38,782,446.06 39,117,077.16 31,594,106.27 34,277,476.31 0.00 329,247,060.52 0.00 317,654,418.42 24,212,228.49 23,547,717.95 22,450,371.51 22,164,558.23 661,330,551.50 964,176,260.27 478,060,838.60 774,305,950.80 66
2005 2 200,694,624.74 160,886,398.95 122,243,095.93 99,195,666.62 156,876,747.17 402,106,192.64 95,715,542.22 362,576,240.45 30,452,446.97 59,242,597.00 18,548,585.45 36,526,449.35 273,306,732.62 341,941,071.68 241,553,615.00 276,007,594.38 661,330,551.50 964,176,260.27 478,060,838.60 774,305,950.80 317,250,032.37, 47.97% 27 1,487,830.99 2,340,098.45 14,045.87-175,000.00 630,644.73 1,002,899.33 2,132,521.59 3,167,997.78 28 11,490,943.01 12,847,417.69 11,022,021.18 12,010,821.27 468,921.83 836,596.42 359,029.06 68,376.07 167,501.82 0.00 191,527.24 68,376.07 69,163.03 19,800.00 5,533.04 1,782.00 63,629.99 18,018.00 1,471,661.52 4,043,415.13 1,471,661.52 4,043,415.13 0.00 0.00 5,118,706.43 1,779,452.26 4,617,930.55 1,778,080.11 500,775.88 1,372.15 18,509,503.05 18,758,461.15 17,284,648.11 17,834,098.51 1,224,854.94 924,362.64 29 24,446,459.74 18,789,404.00 : 2,081,015.31 3,547,171.84 2,871,801.93 314,079.83 67
2005 222,211.98 201,893.52 25,459,458.34 15,758,205.51 30 1,644,313.17 0.00-35.813.72 613,773.57 447,477.10 0.00 0.00 8,139,852.50 13,541.41 0.00 0.00-35.813.72 10,858,957.75 31 15,900.00 29,000.00 109,200.00 385,737.70 37,197.64 18,064.37 162,297.64 432,802.07 32 436,481.41 708,809.80 800.00 41,865.19 3,000.00 3,833.35 440,281.41 754,508.34 68
2005 33 4,118,476.14 2,081,015.31 163,987.67 34 30,535,213.13 6,303,924.36 5,000,000.00 2,164,220.67 1,212,685.88 1,049,435.19 912,275.42 892,406.23 1 % 3 129,617,653.38 97.54 0.00 129,617,653.38 3 2 2,531,888.54 1.91 126,594.43 2,405,294.11 25 724,006.30 0.54 72,400.63 651,605.67 5 9,300.00 0.01 9,300.00 0.00 132,882,848.22 100.00 208,295.06 132,674,553.16 % 3 93,178,730.33 95.92 0.00 93,178,730.33 3 2 3,897,243.41 4.02 194,862.17 3,702,381.24 25 61,300.00 0.06 6,130.00 55,170.00 5 0.00 0.00 0.00 0.00 97,137,273.74 100.00 200,992.17 96,936,281.57 1 94,492,062.97 71.11% 2 9,651,962.31 69
2005 2 % 3 45,767,107.27 100.00 0.00 45,767,107.27 3 2 0.00 0.00 0.00 0.00 25 0.00 0.00 0.00 0.00 5 0.00 0.00 0.00 0.00 45,767,107.27 100.00 0.00 45,767,107.27 % 3 10,090,079.43 96.67 0.00 10,090,079.43 3 2 308,437.14 2.96 15,421.86 293,015.28 25 39,238.40 0.37 3,923.84 35,314.56 10,437,754.97 100.00 19,345.70 10,418,409.27 1 43,080,784.09 94.13% 2 5% 5% 3 2000.4-2015.4 90% 169,534,428.87 0.00 169,291,387.60 0.00 2001.11 51% 9,435,814.57 0.00 9,691,972.66 0.00 2002.10-2022.10 70% 43,748,195.47 0.00 43,680,655.58 0.00 2003.06-2053.06 92% 4,645,883.56 0.00 4,634,894.36 0.00 2000.10-2020.10 8.6% 386,784.29 0.00 386,784.29 0.00 2001.11 7% 5,925,000.00 0.00 5,925,000.00 0.00 2001.11 3.3% 50,000,000.00 0.00 50,000,000.00 0.00 2002.12 20.07% 25,782,332.22 0.00 21,573,326.41 0.00 70
2005 2005.7-80% 4,000,000.00 0.00 0.00 0.00 2025.7 313,458,438.98 0.00 305,184,020.90 0.00 167,510,000.00 0.00 1,620,275.10 1,377,233.83 2,024,428.87 9,200,680.00 0.00 485,409.52 741,567.61 235,134.57 44,800,000.00 0.00 67,539.89 0.00-1,051,804.53 4,600,000.00 0.00 10,989.20 0.00 45,883.56 20,000,000.00 0.00 4,209,005.81 0.00 5,782,332.22 4,000,000.00 4,000,000.00 0.00 0.00 0.00 250,110,680.00 4,000,000.00 6,393,219.52 2,118,801.44 7,035,974.69 2005 6 5,000,000.00 80% 4 1 458,333,859.31 561,614,900.26 381,849,534.29 429,703,751.28 1,747,777.35 1,182,105.86 620,694.75 329,852.65 375,558,832.00 452,285,000.00 307,802,881.29 424,435,311.20 13,914,469.05 11,586,814.87 13,123,567.55 12,063,193.72 849,554,937.71 1,026,668,820.99 703,396,677.88 866,532,108.85 71
2005 2 112,448,454.97 137,296,747.44 87,529,877.35 115,535,212.97 707,669,157.95 831,289,785.52 592,952,786.92 702,120,650.50 29,437,324.79 58,082,288.03 22,914,013.61 48,876,245.38 849,554,937.71 1,026,668,820.99 703,396,677.88 866,532,108.85 672,621,986.83 79.17% 5 1,644,313.17 447,477.10 2,343,923.23 7,600,243.95 8,139,852.50 2, 343,923.23 17,831,886.72 1 1 2000.8.8 91 2001.11.12 91 72
2005 109 2000.4.28 2001.4.16 7 2002.10.28 2003.6.13 9 2005.7.5 73 2 674,970,000.00 0.00 0.00 674,970,000.00 841,920,000.00 0.00 0.00 841,920,000.00 180,000,000.00 0.00 0.00 180,000,000.00 18,040,550.00 0.00 0.00 18,040,550.00 64,000,000.00 0.00 0.00 64,000,000.00 5,000,000.00 0.00 0.00 5,000,000.00 0.00 5,000,000.00 0.00 5,000,000.00 3 % % % % 169,015,012.00 67.12 27,787,596.00 11.04 141,227,416.00 56.08 162,000,000.00 90 162,000,000.00 90 9,200,680.00 51 9,200,680.00 51 44,800,000.00 70 44,800,000.00 70 4,600,000.00 92 4,600,000.00 92 0.00 0.00 4,000,000.00 80 0.00 0.00 4,000,000.00 80
2005 4 2 1 %) (%) 124,464.64 0.02 7,774,839.14 1.73 0.00 41,547,548.29 7.01 35,729,301.36 7.94 1,342,387.21 18,121,785.65 3.06 18,766,906.88 4.17 0.00 0.00 0.00 90.00 0.00 0.00 0.00 0.00 85,470.09 0.02 0.00 357,891.68 0.06 78,372.98 0.02 48,341.43 0.00 0.00 5,483.27 0.00 0.00 0.00 0.00 820.00 0.00 0.00 60,151,690.26 10.15 62,441,283.72 13.88 1,390,728.64 2 (%) (%) 18,016,575.13 2.72 9,666,888.92 1.00 8,249,540.44 41,515,952.96 6.28 23,458,951.62 2.43 9,288,191.49 9,330,769.28 1.41 10,324,358.97 1.07 3,090,002.48 74
2005 10,214,529.88 1.54 13,067,478.61 1.36 2,420,956.97 1,853,241.71 0.28 868,769.23 0.09 0.00 0.00 0.00 2,100,000.00 0.22 0.00 20,751,485.84 3.14 16,349,430.70 1.70 5,177,602.25 84,783,520.71 12.82 137,916,937.73 14.30 43,006,511.01 80,333.68 0.01 0.00 0.00 0.00 35,145.30 0.01 12,222.22 0.00 0.00 186,581,554.49 28.21 213,765,038.00 22.17 71,232,804.64 3 <1> 33,608.28 23,748.94 1,731,445.00 1,614,171.40 2,271,145.09 2,405,494.79 <2> 4,789,643.96 1,557,262.20 <3> 296,099.04 257,296.04 300,000.00 300,000.00 1,406,470.55 1,222,156.22 <4> 54,097.44 58,500.00 <5> 1,048,645.01 2,041,596.57 29,300.00 0.00 75
2005 <6> 268,508.04 350,666.79 <7> 2,441,947.87 2,506,746.23 <8> 605,599.90 1,102,108.47 <9> 1,214,520.00 1,214,520.00 <10> 110 613,659.73 971,895.24 <11> 472,263.29 191,782.91 <12> 0.00 1,240,000.00 3 (%) (%) 9,651,962.31 4.34 0.00 0.00 10,867,184.04 4.89 201,877.00 0.13 0.00 0.00 110,000.00 0.07 3,615,302.90 1.63 2,625,691.32 1.68 2,832,519.66 1.27 1,278,343.80 0.82 5,177,602.25 2.33 1,366,781.21 0.88 43,006,511.01 19.34 40,294,835.48 25.83 660,000.00 6.54 0.00 0.00 21,509.61 0.21 0.00 0.00 16,885,262.00 88.52 0.00 0.00 20,401,869.06 54.24 0.00 0.00 0.00 0.00 294,000.00 0.54 1,570,593.03 1.17 0.00 0.00 76
2005 56,559.47 0.04 0.00 0.00 200,000.00 3.66 0.00 0.00 1,100.00 0.02 500,000.00 18.08 300,000.00 6.59 300,000.00 10.85 80,803,526.36 81,015,897.79-326,322.10 45,000.00 84,463.25 44,858.14-60,370.72-212,371.43 3,000,000.00 2005 9 23 2006 3 22 1 2004 251,825,012 10 1 25,182,501.20 2005 3 2004 2 2005 251,825,012 10 0.5 12,591,250.60 231,996,207.17 2005 2005 251,825,012 10 8 77
2005 32005 4 1 2005 10 10 2005 4 2004 7 16 2004 A 2005 7 15 2005 78
2005 % 18.18 18.84 0,719 0.719 9.56 9.91 0.378 0.378 8.11 8.40 0.321 0.321 8.13 8.43 0.322 0.322 636,831.44 82,564.11 554,267.33 600,793.96 57,452.69 543,341.27 36,037.48 25,111.42 10,926.06 0.00 0.00 0.00 736,291.37 14,070.68 31,310.84 719,051.21 643,240.45 19,698.41 623,542.04 71,484.70 14,042.60 85,527.30 8.37 28.08 36.45 3,418.07 974.65 2,443.42 18,139.78 10,637.78 7,502.00 0.00 0.00 0.00 79
2005 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 222,322,419.52 155,402,368.02 43.06% 19,075,971.28 2,948,782.91 546.91% 575,646,815.45 329,144,076.12 74.89% 207,781,760.61 108,040,310.08 92.32% 460,939,492.16 161,788,333.36 184.90% 37,611,869.06 8,000,000.00 370.15% 133,844,871.00 54,743,279.11 144.50% 661,330,551.50 964,176,260.27-31.41% 478,060,838.60 774,305,950.80-38.26% -35.813.72 10,858,957.75-100.33% 80
2005 12 1 2 3 4 2006 3 6 81
2005 2005 2 < > 2005 2005 1 2005 2 2005 2005 82
2005 00 83