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EasyMax HFCal www.mt.com/hfcal-ch 过程安全指南 Calorimetry Guide 产品聚焦 在开发的不同阶段 需要使用不 同类型或质量的信息 梅特勒-托 利多的 EasyMax HFCal 通常用于量 热筛查 并识别可扩展性问题 而 OptiMax HFCal 则是放大生产和 安全性研究的理想之选 工业标 准 RC1e 适合对过程安全性进行全 面研究 具有无可比拟的准确度 和精度 Safety by Design What do we Learn from Reaction Calorimetry? Developing new compounds and transferring them to manufacturing requires an understanding of the chemical route, process and all its parameters. Therefore, knowing the scale-up as well as the safety-related parameters is equally important to ensure a chemical process is safe at scale. Generally, the earlier critical conditions are recognized, the easier and faster the process can be adjusted and properly designed and implemented. The experiment results may even require scientists to choose a different route. Ultimately, reducing time and resources as well as speeding the chemical workflow is the result of acquiring better information earlier. In a simplified approach, the chemical and process development workflow begins with Chemical Synthesis in which the chemical and physical information and chemical route are key. Often a small quantity of the product is made for testing purposes as an integral part of this step before the development workflow continues. Applying traditional development tools no longer supports today s requirements. Thus, both the technology as well as the procedure applied must be adapted to meet today s needs in full. Contents 1 Screening for Scalability Risks 2 Key Information for Moving a Process from Lab to Plant 3 What is the Value of Reaction Calorimetry? 4 Knowing the True Heat Release Pattern 5 Understanding Maximum Heat Release Rate and Adiabatic Temperature Increase 6 Conclusions 该手册在讨论设计安全工艺时必 须考虑到的挑战 失控情况及风险 评估等 立即下载本白皮书 www.mt.com/ac-psguide-ch 梅特勒-托利多 化学品快讯 7 11
www.mt.com/ind-catalog-ch IEC 60079-17 IEC - www.mt.com/ind-ex-service-ch METTLER TOLEDO Group Industrial Division www.mt.com/contacts www.mt.com/ind-ch 09/2017 METTLER TOLEDO. 30327620 MarCom Industrial