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2007-06-23 850000 500000 2002 16.93/10 9.96/10 36.1/10 5 90% <10% <1cm 10 >50 1~2cm 10%>2cm 31.4%~50% 5%~9% 9% 40 %~50% 50% 20 %~30% >50 : (familial adenomatous polyposis,fap hereditary nonpolyposis colon cancer,hnpcc 1 50 101 1 51 + 51 1cm (invasive cancer)
2 76% 76%~90% ~90% 2%~5% 2%~5% 58.6% 58.6% 0.1%~0.2% 0.1%~0.2% 5mm 5mm 27 27% 10mm 10mm 6% 3 3 2 23.9% 23.9% 15% 15%~33% ~33% 4 70.3% 70.3% 60% 60%~80% ~80% 3 60 60 5 + 1 75.3% 75.3% 6 6~10mm 10mm 53% 53% >1cm >1cm 48% 48% 83% 83% 95% 95% CT CT 10mm 10mm 55% 55%~100% ~100% 94% 94%~98% ~98% DNA DNA 4 2 1 FAP FAP APC APC + - APC(?) APC(?) (+) ( (+) (-) 10~12 10~12 1 40 40 3~5 3~5 1 7~10 7~10 1 40 40 5 1 10~12 10~12 1
HNPCC 2 44 20~25-10 1~2 1 40 3 40 10 <60 3~5 40 60 5 40 10 <60 5 60 4 P 61 54 29/25 NBI 63 26/37 62 / 36/25 24/38 0.088 54.9015.05 50.6715.40 52.1112.69 53.3213.45 0.423 NBI63 P 1 4 61 3 > 0.05 5 13 18 18 26 4 3 > 0.05 1 7 17 28 22 38 1 4 61 13 18 5 4 54 23 32 5 P < 0.05 > 0.05 4 1 4 17 19 22 28
1 4 61 13 18 4 1 17 22 P min 9.884.18 12.127.1 1 0.04 5 P 2.411.9 8 2.352.0 0 0.888 (RMB) P 461.86102.2 8 435.98110.6 7 0.205 4 62 P > 0.05 1 9 14 8 < 0.01 8 39 55 NBI 14.327.5 3 13.037.0 3 0.00 0 0.00 4 3.002.3 6 2.722.1 5 0.136 0.406 488.73100.8 1 468.64107.4 4 0.147 0.726 NBI 8~10 1~2
2%~30% 2 <1cm 1 5 3~5 3~10 3 14 5 10 3 2~6 1 0.5cm 1. ASGE guidelilne: colorectal cancer screening and surveillance, Gastrointestinal endoscopy2006;63(4)546-5757 2. WGO practice guideline:colorectal cancer screening and surveillance. Summer 2002 3. Winawer SJ et al.guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society.Gastroenterology.. 2006;130(6):1872-85. 85. 4. Winawer SJ, Zauber AG.The advanced adenoma as the primary target of screening. Gastrointest Endosc Clin N Am. 2002 Jan;12(1):1-9, v. 5.. 1998123 298-9
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APCEMRESD
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