9 1 1997 3 V o l. 9 N o. 1 PRO GR ESS IN CH EM ISTR Y M ar., 1997 3 3 3 ( 100085) ( 100083), Progress in B iomarkers Research and R isk A ssessm en t for Env ironm en ta l Carc inogen s Q in T aoz hao L ix inx u X iaoba i (R esearch Cen ter fo r Eco2Environm en tal Sciences, Ch inese A cadem y of Sciences, B eijing 100085, Ch ina) J in Z u liang (N ational N atu ral Sciences Foundation Comm ittee, Beijing 100083, Ch ina) Abstract T he research fo r b iom arkers has been regarded as an encou raging and p rom ising app roach in the risk assessm en t fo r environm en tal carcinogen ṡ B iom arkers m ay fu rn ish the critical info rm ation abou t expo su re levels and b io logical effectṡ T h is paper re2 view s the cu rren t statu s and trends of the studies on b iom arkers and risk assessm en t fo r environm en tal carcinogen s, as w ell as their im po rtan t ro les in the strategy of the p rio rity p rogram of risk. Key wordsenvironm en tal carcinogen s; risk assessm en t; b iom arkers : 1996 1, : 1996 10 3 3 3
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34 9 EPA : (1) (2),, (3), 2DNA (4) ( ),,,,?? [ 36, 37 ],, H PL C GC GC2M S,,,,,,,,,,, 15, 30, 2,, [1 ] R eilly W K, E PA J ou rnal, 1991, M arch A p ril, 25. [2 ] H arry A M, E nv ironm ental S cience R esearch, 1983, 29, 35. [3 ] W assersgu S R, W ater E nv iron. & T echnol., 1990, N ov., 4245. [4 ] L oeh r R, E PA J ou rnal, 1991, 17 (2), 612. [5 ] K im drough R D, E nv iron. S ci. T echnol., 1990, 24 (10), 14421445. [6 ],, 1994, (4), 561 [7 ] ICPEM C Publication N o. 2, M u taṫ R eṡ, 1979, 64, 155158. [8 ] Eh renberg L, To rnqvist M, T ox icology L etters, 1992, 64 65, 485492. [9 ] Perera F P, E nv iron. H ealth P ersp ecṫ, 1991, 94, 231235.
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