16 2015 2015 2013116,950.7 2014135,749.22015146,568.12013 201420155,454.65,491.9 6,082.2 1.520206.2
2015 2015 (i) (ii) (iii) 2007 2007
6S 20062010301.4% 2010 60 2010201554.0% 68.0% 20151231 28715993975 2015321004 50010610 20112016 WPP 20142015Interbrand50 2015300,000
2015 NICU 2015123180 GMPcGMPGMPWHO PQ 2014F. Hoffmann-La Roche Ltd.
2013 2015 2015123132 207 2015 19114 8,000317 2015 61.1% 2015123165,000 1,011 10,000201512 3153 111700,000 2015123189.5%(Warehouse Management System)
702 2015 2015123122 35 2015 201536 2011 2015123128
(i)(ii) (iii) 2015500115 70
6S 5C 19
DTP ERP(WMS) B2BB2CO2O B2B B2C
O2O 20166
2020 [][]%
KPI (Pharmacy Benefit Management) 16
1231 2013 2014 2015... 20,837.2 1,478.2 22,315.4 19,713.8 2,253.2 21,967.0 21,606.6 2,647.0 24,253.6... 91,651.9 905.2 92,557.1 111,789.8 1,307.9 113,097.7 121,190.9 1,965.5 123,156.4... 2,600.6 2,600.6 3,040.3 3,040.3 3,651.2 3,651.2... 1,861.0 1,861.0 1,205.3 1,205.3 119.4 119.4... (2,383.4 ) (2,383.4) (3,561.1 ) (3,561.1 ) (4,612.5) (4,612.5 )... 116,950.7 116,950.7 135,749.2 135,749.2 146,568.1 146,568.1 2015 201320142015 20,837.219,713.821,606.6 22,315.421,967.024,253.6 20151231494287159 939301288 126201532 100.0610 04 50010 0 20151231
999 2015123132 20 201512312,769 1231 2013 2014 2015... 9,020.3 40.4% 9,144.2 41.6% 9,406.9 38.8%... 10,105.2 45.3 10,908.6 49.7 12,336.5 50.9... 116.6 0.5 41.4 0.2 197.9 0.8... 303.1 1.4 374.6 1.7 382.5 1.6 (1)... 2,770.2 12.4 1,498.2 6.8 1,929.8 7.9... 22,315.4 100.0% 21,967.0 100.0% 24,253.6 100.0% (1) 2013
(i) (ii) (iii) 2013201420159,020.3 9,144.29,406.940.4%41.6% 38.8% 20151231... 0... 2028 10... 20289 2032 6... 20289 2032 6... 2030 12... 2033 4 II... 2034 8... 2033 4...
...... BFS..................... 2023 5... 2028 11... 2031 6...... 20319 2032 3...
............... 2013290 (i) 0 201510 (ii) 2011FDA(ANDA) 2015500.010
(iii) 2013201547.6% (iv) 20132015123.4% (v) 20151160% II 2013201420151,652.8 1,827.62,044.8 2015 2079109.6 2 201320142015270.8 274.3300.4 BFS 20132015 359.4%FDA 2015 20
2013201420153,006.8 3,011.92,631.52015 201320142015636.8 529.5753.7 (i) 2015 (ii) (iii) 20158 2014128.0 20140.4 20132014201565.7 76.4100.82015 6.3%
2015 201116.0201516.6 0.8%202019.3 3.1% (i) (ii) 2015 76.5% (iii) 201320142015473.8 621.4552.1 (i) 2015 35.1% 23.5% (ii)
201320142015493.1 573.6632.7 (i) 201531.2% (ii) 201320142015745.8 673.7743.9 (i) (ii) (iii) 20162 2016-2030 201320142015 10,105.210,908.612,336.5 45.3%49.7%50.9%53
20151231......... 2031 3......... 2026 10... 2027 1...... 2025 2......... 2034 9... 2026 4... 2026 4... 2026 10... 2023 8......... 2030 12... 2029 12...
20142015Interbrand 50 2013201420153,287.9 3,835.45,010.0 2015 2.3% 999 392013201420152,084.0 2,162.52,293.5 2015 7.9% 20132014 2015164.9108.0145.7 201320142015943.7 944.8989.2
201320142015200.3247.0 243.8 201320142015 323.7414.4458.4 2013297.18% 20132014 20151,114.51,049.7973.2 2013 2015 201320142015181.9 198.6238.9
20151231694201320142015 735.9754.21,107.2 2015 201320142015116.641.4 197.90.5%0.2%0.8% (i) (ii) (iii)11 201320142015303.1 374.6382.51.4% 1.7% 1.6%2013 201533.6%
(i) (ii) (iii) 201512311571217 4454 362219 251110 20151231921 2011201510814 20 201320142015 635.5851.4926.8
15201512 3160040% 35%1060
(CRO) CRO GCP 201512313220 7 (DEFINITY)2001 DEFINITY 201612016 Nitto Denko Technical Corporation1.1
20152079 1.096 JAK1 1.1 BTKB BTK BTK BTK (SPRM) 120III 2018 0.10mg 0.02mg III 2019
BFS BFSBFS BFS2012BFS BFS BFS BFS 20162017 FDA(ANDA) 2017 (r-pa)
(1) (2) 20163
2015123140288 3,800,0001,800,000 172015 1231 20151231 1231 2013 2014 2015 (1) (1) (2) (1) (1) (2) (1) (1) (2)... 9,671.8 4,597.4 47.5% 10,026.5 5,790.5 57.8% 9,983.3 5,127.8 51.4%... 5,071.5 3,036.6 59.9% 5,351.9 3,278.1 61.3% 6,210.6 4,276.4 68.9%... 2,665.3 897.1 33.7% 3,006.3 885.0 29.4% 3,113.9 1,016.0 32.6%... 2,432.3 1,202.9 49.5% 2,454.0 1,862.2 75.9% 2,484.0 1,351.4 54.4%... 2,238.8 1,679.3 75.0% 2,246.4 1,762.6 78.5% 2,130.1 1,532.0 71.9%... 727.7 563.5 77.4% 771.1 538.7 69.9% 894.9 478.6 53.5%... 258.7 100.0 38.7% 237.2 79.8 33.6% 237.2 98.5 41.5%... 241.9 106.8 44.2% 207.4 127.8 61.6% 207.4 115.9 55.9%... 1,336.2 1,046.0 78.3% 1,336.2 962.5 72.0% 1,336.2 1,017.3 76.1%... 1,359.5 711.5 52.3% 1,359.5 759.6 55.9% 1,568.5 876.2 55.9%... 2,100.0 2,361.0 112.4% 2,100.0 1,900.0 90.5% 2,100.0 2,003.0 95.4% (1) (2)
201320142015 (i) (ii)gmp (iii) (iv) 20151231 11 (GAP)
3090 3090 999 20112016WPP 20132015
20142015Interbrand 502015 201515 2012
2015123180 NICU (PIVAS) 2015300,000
1231 2013 2014 2015... 2,454 2,579 2,548... 429 359 431... (304) (390) (210)... 125 (31) 221... 2,579 2,548 2,769
i. ii. iii. iv. v. vi. 2013 20142015 vii.
viii. ix. x. 30120 xi. 201320142015 6.6%10.3%10.9%
201561 20155 201561
201529 2015611 2015 20151231114 11119 2013 2014201591,651.9 111,789.8121,190.992,557.1 113,097.7123,156.4 2015123120,1209,85942 9,69650 200201512 3153 2015 61.1%20151231114
1111,0113,02240,778 1231 2013 2014 2015... 55,811.5 60.9% 67,828.3 60.7% 74,082.1 61.1%... 32,501.5 35.5 39,945.8 35.7 43,008.3 35.5... 3,338.9 3.6 4,015.7 3.6 4,100.5 3.4... 91,651.9 100.0 111,789.8 100.0 121,190.9 100.0... 905.2 1.0 1,307.9 1.2 1,965.5 1.6... 92,557.1 101.0% 113,097.7 101.2% 123,156.4 101.6%
201561.1% 6%8%
3%5% 2%4% 0.5%2% 3%5% 20151231114111 1944,811
2013 70.0%2015 2011 51.0% 2014100.0% 1231 2013 2014 2015 (1)... 32,442.8 35.4% 37,036.7 33.1% 39,426.4 32.5% (2)... 24,294.7 26.5 30,112.4 26.9 34,336.6 28.3 (3)... 16,727.9 18.2 20,438.3 18.3 22,008.5 18.2 (4)... 8,207.4 9.0 9,869.0 8.8 10,513.1 8.7 (5)... 7,211.4 7.9 10,810.4 9.7 11,744.9 9.7 (6)... 2,767.7 3.0 3,523.0 3.2 3,161.4 2.6... 91,651.9 100.0% 111,789.8 100.0% 121,190.9 100.0% (1) (2) (3) (4) (5) (6)
2015123144,8118,222 20,869 (i)(ii) (iii) (iv)2,000
20151231 20151231 (1)... 15,597 1,653 5,946 23,196 (2)... 12,122 908 5,291 18,321 (3)... 8,141 2,078 5,022 15,241 (4)... 6,852 1,694 2,883 11,429 (5)... 1,111 908 1,455 3,474 (6)... 988 981 272 2,241... 44,811 8,222 20,869 73,902 (1) (2) (3) (4) (5) (6) 201320142015 55,811.567,828.374,082.1 60.9%60.7%61.1%
2013201420156,1616,5048,222 2014 20132014 2015 1231 2013 2014 2015... 4,617 6,161 6,504... 1,546 2,528 1,945... (2) (2,185) (227)... 1,544 343 1,718... 6,161 6,504 8,222 20132014201532,501.5 39,945.843,008.3 35.5%35.7%35.5%
201320142015 3,338.94,015.74,100.5 3.6%3.6%3.4% 24060 2013201420152117 202.2%1.5%1.7%
9,69650 200 2015123153 201320142015 GMPGSP 2015123174,000
9,696 2015123130,137 20,120 9,859 42 17,040 6,978 20151231... 3,828... 3,001... 1,801... 1,547... 1,248... 981... 917 18... 769... 705 VIII
... 624... 461... 259... 162... 128 b... b... 35... 315... 12,933... 294... 129 20151231... 32,461... 1,989... 5,531... 959... 3,302 3
20151231100 201519 1113081699,500 411,00065,300 2015123167 70%
41224 48 16 20159 201320142015 2,600.63,040.33,651.2
1620151231 70268121 40320151231 (1)... 455 15 470... 86 0 86 (2)... 55 6 61 (3)... 38 0 38 (4)... 28 0 28 (5)... 17 0 17 (6)... 2 0 2... 681 21 702 (1) (2) (3) (4) (5) (6) 2015123170216 2015123121
201320142015 5,044 4,245 5,296 2,547 5,696
2013201420153.6% 4.5%4.4%0.9%1.3%1.1% 201320142015 5%
201320142015 20.2%21.7%21.0%7.2% 7.7%7.6% 5% 2.B. 10 999
2015 5,000 Bayer AG
2015 GSP 10 201140.3%201548.3% 201513,000 2015
2014434.9 201320142015 [133][187][207] 201320142015
2013201420153234 35 20132014 2015837160 GMPGSP
GMP GMP 20151231
201523 2014 0.1% 2016
2013820165 18 2013 2013
(i)(ii) (iii)
201320142015
20132014201529.238.641.3 (i) (ii) (iii)(iv) (v)
52,506... 933 1.78%... 7,995 15.23%... 1,035 1.97%... 3,095 5.89%... 5,875 11.19%... 16,204 30.86%... 13,189 25.12%... 1,894 3.61% (1)... 2,286 4.35%... 52,506 100.00% (1)
2013201420155,560.1 6,414.76,481.9 2641 201512316.7% 15% 34(2)342(1)(b) 1,0162,741,733.9 3387,221,532.8618 541,378.8281,512,237.0 2,741,733.91,016 22.8%
1,0162,119,660.9851 77.3% 851 165622,073.0 22.7% 165 523,507.30.9% 2016 56,394.70.2% 22350,811.512.8% 3711,394.90.4%
(i)(ii) 96229,964.6 8.4%(i) (ii)(iii) 96 (a)9641168,007.7 6.1% (b)5561,957.0 2.3% 9696 (i) 5%10%(ii) 10% (i) 6.1%(ii)
(iii) 96 618541,378.8 4.5% 618 494397,074.3 73.3%494 124144,304.4 26.7% 124 108113,796.621.0% 325,666.14.7% 2016 134,841.80.9% (a) (b) (c)
(d) 3387,221,532.8 60.1% 3382965,968,518.3 82.6% 421,253,014.5 17.4%42 4229 1,114,913.3 15.4% 2916174,544.0 2.4% 13940,369.3 13.0% (a) (b) 4213 138,101.2 1.9%13
(a) 135 45,192.50.6%5 (a)(b) (b) 892,908.7 1.3%84 65,422.30.9% 427,486.4 0.4% (a) (b) 281,512,237.0 12.6% 2812937,486.3 62.0%
2816574,750.7 38.0% 16 340,668.022.5% (a) 67,333.44.4% 2016 (b) 273,334.7 18.1% 13234,082.6 15.5% 13 (a) 130,073.58.6% (a) 2016(b) (c)
(b) 65,326.4 4.3% 30 (c) 38,682.8 2.6% 30 201612 2562,898 815,375 44,102.4 833528 18
(i) (ii)(iii)