. - 2 -
- 3 -
- 4 -
2008 3 15 2008 4-10 500 2008 4 8 2008 9 30 65 2 10-5 -
10 14 10 18 11 4 3.15 mg/kg 5 2 20 11 18-6 -
/ - 7 -
/ 7 66 300 9 2 550-8 -
- 9 -
11 19 Alpha MOS (NQAD) (CLND) 96PKaLogP - 10 -
2008 5 12 8.0 2008 6 19-11 -
2008 7 18 2008 7 24 7 25-12 -
2005-13 -
9 12-14 -
2008 35 15 10 16-15 -
-1940 67 1500 2000 54 1994 R. Erv Taylor 17 9400-16 -