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1 PROTEOL APL 1

3 1 - PROTEOL APL PROTEOL APL 2 - PROTEOL APL - PROTEOL APL - PROTEOL APL PROTEOL APL - PROTEOL APL ( ) PROTEOL APL ( 1) PROTEOL APL - ( ) ( ) - PROTEOL APL ( 3.2 ) - 3

4 Softness of the foam Ease of rinsing Softness on the skin Stability of the foam Abundance of the foam Density of the foam 1 PROTEOL APL 1 PROTEOL APL 3000 rpm 2 min 0.1% 40 C ph 7 15x PROTEOL APL Ross-Miles PROTEOL APL 4

the foam 1 PROTEOL APL 1 PROTEOL APL 3000 rpm 2 min 0.

5 ( 2 ) PROTEOL APL (ml) PROTEOL APL NaLES Sodium lauroyl sarcosinate 10 Sodium lauroyl glutamate + 2 Ross-Miles (ISO , AFNOR NFT ) 1% ph 7 PROTEOL APL 5

6 NaLES PROTEOL APL 1% PROTEOL APL ( 3 ) Foam in hard water + dirt Foam volume (ml) NaLES 242 NaLES + Sodium lauroyl glutamate NaLES + PROTEOL APL 3 (NaLES/ : 9/1% ) Ross-Miles (ISO , AFNOR NFT ) - 1% PROTEOL APL 6

7 4 - PROTEOL APL PROTEOL APL PROTEOL APL (SEPPIC 57CO009 annex IV of the order of 29 November 1996 published in the JO no. 300 of 26/12/96, page 19137). HET-CAM: Dose-response comparison of anionic surfactants % a.m. 0.5% a.m. 2 0 PROTEOL APL Sodium lauroyl sarcosinate NaLES 4: HET-CAM : 0.1% 0.5%. Note: The results obtained by the HET-CAM method are comparable with the results obtained by the Draize test (in vivo method) at 10-fold higher concentrations. 7

300 of 26/12/96, page 19137). HET-CAM: Dose-response comp

8 PROTEOL APL ; 0.5% PROTEOL APL 5. (SEPPIC HET-CAM ) PROTEOL APL (RBCA) RBCA Surfactant-induced denaturation of oxyhemoglobin 100 % denaturation % am 10% am 0 NaLES PROTEOL APL Graphe n 5 : Evaluation du pouvoir dénaturant vis-à-vis de l oxyhémoglobine : nm : OD 575 nm/od 540 nm; PROTEOL APL : SEPPIC toxrbca995. 8

denaturation 80 60 40 20 5% am 10% am 0 NaLES PROTEOL APL Graphe n 5 : Evaluation du

9 (SEPPIC 57CO002) NFT (ISO amended) 6 PROTEOL APL NaLES 25 C 0.1% Assessment of wetting power time (seconds) PROTEOL APL NaLES PROTEOL APL NaLES 6: PROTEOL APL NaLES PROTEOL APL PROTEOL APL FINNCHAMBER PROTEOL APL (DERMSCAN ) 9

1% Assessment of wetting power 120 100 80 time (seconds) 60 40 20 0

10 PROTEOL APL PROTEOL APL (Chapter th edition, January 2002 Effectiveness of microbial contamination Criteria A, refer to MIDAC expert report ). PROTEOL APL 5 - PROTEOL APL 301 B PROTEOL APL 28 95% (i.e. > 60%). PROTEOL APL 6 - PROTEOL APL 10% PROTEOL APL 10

Criteria A, refer to MIDAC expert report 03 365 289).

11 PROTEOL APL PROTEOL. APL - PROTEOL APL ph 7 - NaLES PROTEOL APL ph 5 PROTEOL APL PROTEOL APL - NaCl - ( CAPIGEL 98, SEPPIC 6857) - ( AMONYL 380 BA, SEPPIC 6958) - ( MONTALINE C40 SEPPIC 6960) ( ) 0.1%, 0.5% 0.8% ph 7 PROTEOL APL 0 NaLES (0.1% ) (0.5% 0.8% ) SEPPIC HET-CAM PROTEOL APL ph 7 5% 10% PROTEOL APL (DERMSCAN ) MARZULLI MAIBACH. 11

SEPPIC 6857) - ( AMONYL 380 BA, SEPPIC 6958) - ( MONTALINE C40 SEPPIC 6960) - 7 - ( 1996 12 26 )

12 (as is) Max. 150 Hazen ph (as is) % % Max. 100 /g / Max. 100/g INCI Sodium Cocoyl Apple Amino Acids CAS PROTEOL APL SEPPIC PROTEOL APL 12

13 EXTRA-GENTLE CLEAR BABY SHAMPOO 6957 Formula A ORONAL LCG (Sodium coceth sulfate and PEG40 glyceryl cocoate 13.0 % SEPPIC) PROTEOL APL (Sodium cocoyl apple amino acids SEPPIC) 7.0 % SEPICIDE HB (Phenoxyethanol/Methylparaben/Ethylparaben 0.3 % /Propylparaben /Butylparaben - SEPPIC) Parfum / Fragrance 0.2 % B CAPIGEL 98 (Acrylates copolymer SEPPIC) 3.5 % Aqua / Water 10.0 % C Aqua / Water Qsp 100 % D Triethanolamine 0.65 % SEPICIDE CI (Imidazolidinyl urea - SEPPIC) 0.2 % E Sodium chloride Qs Procedure Weight all the ingredients of phase A and mix well after adding each of them. Mix the ingredients of phase B and add it to phase A. Add phase C and D (the ph is adjusted to 7.2 with the Triethanolamine). If necessary, the viscosity is lowered with the addition of phase E (1% max). Comments ORONAL LCG PROTEOL APL CAPIGEL 98 SEPICIDE HB SEPICIDE CI Ultra mild surfactant that is extremely well tolerated by skin and eyes. It is well suited for formulation of products that require perfect tolerance (makeup removers, products for babies or sensitive skin, etc.). It allows formulation of colourless products. Fruit surfactant, derived from apple juice essential amino-acids, for a gentle approach : gentle approach for the touch, for the skin & the eyes and also for the environnement. CAPIGEL 98 is a liquid thickener that is used at ph7. CAPIGEL 98 is especially useful to thicken low-concentration surfactant systems such as foaming facial cleansers, products for babies and intimate hygiene gels. CAPIGEL 98 can also be used to obtain perfectly clear and colorless skincare gels. Preservative. Preservative. 13

0 % C Aqua / Water Qsp 100 % D Triethanolamine 0.65 % SEPICIDE CI (Imidazolidinyl urea - SEPPIC) 0.

14 Characteristics Aspect Clear ph Around 7.2 Viscosity Around 4,000 mpa.s / Brookfield LV2 6rpm Stability Stable at RT 40 C 4 C Assessment HET-CAM test at a 10% dilution: score = 0 / non irritant (SEPPIC method 57CO009) Notes Fragrance : Musty Ref PN (QUEST) 14

15 MOISTURIZING CLEANSING FRUIT WIPES 6959 Formula A PROTEOL APL (Sodium cocoyl apple amino acids SEPPIC) % AQUAXYL (Xylitylglucoside and anhydroxylitol and xylitol SEPPIC) % B SEPICIDE HB2 (Phenoxyethanol/Methylparaben/Ethylparaben % /Propylparaben /Butylparaben/Isobutylparaben - SEPPIC) Parfum / Fragrance % Hexylene glycol % C Aqua / Water Qsp 100 % Procédure Mix ingredients from phase B until the mixture becomes clear, then add phase A, then C. Comments PROTEOL APL Fruit surfactant, derived from apple juice essential amino-acids, for a gentle approach : gentle approach for the touch, for the skin & the eyes and also for the environnement. AQUAXYL New "AQUACONCEPT " technology : thanks to an harmonization of the skin's hydrous flow, AQUAXYL TM moisturizes and restructures the skin ; Water reserves are instantly boosted and water loss is reduced (in vitro and in vivo proven efficacy) for a more supple and resilient skin!" SEPICIDE HB2 Preservative Characteristics Aspect Clear, colorless lotion ph around 7 Viscosity < 50 mpa.s Brookfield LV Stability Stable at RT and 40 C Notes Fragrance : Paradise (SYMRISE) 15

00 % C Aqua / Water Qsp 100 % Procédure Mix ingredients from phase B until the mixture becomes clear, then add phase A, then C.

16 TWO-PHASE SHOWER GEL «GREEN APPLE» 6958 Formula A Sodium laureth sulfate 14.0 % PROTEOL APL (Sodium cocoyl apple amino acids SEPPIC) 5.0 % AMONYL 380BA (Cocamidopropyl betain SEPPIC) 5.0 % Glycerin 0.8 % Parfum / Fragrance 2.0 % MONTANOX 20DF (Polysorbate 20 SEPPIC) 0.5 % SEPICIDE HB (Phenoxyethanol/Methylparaben/Ethylparaben /Propylparaben 0.3 % /Butylparaben - SEPPIC) SEPICIDE CI (Imidazolidinyl urea - SEPPIC) 0.2 % Colorant / Dye 0.01 % Aqua / Water Qsp 100% B Polyisobutene 22.0 % C Lactic acid 0.1 % Procedure Solubilize Sodium laureth sulfate in the water then add the ingredient of phase A, mix well after adding each of them. Introduce phase B into phase A under moderate stirring. Adjust the ph with C component. Comments PROTEOL APL AMONYL 380BA MONTANOX 20DF SEPICIDE HB SEPICIDE CI Fruit surfactant, derived from apple juice essential amino-acids, for a gentle approach : gentle approach for the touch, for the skin & the eyes and also for the environnement. Amphoteric co-surfactant. Solubilizing surfactant. Preservative. Preservative. 16

3 % /Butylparaben - SEPPIC) SEPICIDE CI (Imidazolidinyl urea - SEPPIC) 0.2 % Colorant / Dye 0.01 % Aqua / Water Qsp 100% B Polyisobutene 22.0 % C Lactic acid 0.

17 Characteristics Aspect Bi-phasic solution : green phase on the bottom white phase on the top ph around 6 Viscosité < 50 mpa.s Stability Stable at RT 40 C 4 C Notes Dye : Vert Ref W7000 (WACKHERR) Fragrance : Pomme Granny Ref X (QUEST) 17

mpa.s Stability Stable at RT 40 C 4 C Notes Dye : Vert Ref

18 ENERGIZING CLEANSING GEL 6960 Formula A Sodium lauryl sulfate 5.9 % Aqua / Water Qsp 100 % B PROTEOL APL (Sodium cocoyl apple amino acids) 5.0 % MONTALINE C40 (Cocamidopropyl betaïnamide MEA chloride SEPPIC) 5.0 % SEPITONIC M3 (Magnesium aspartate & Zinc gluconate & Copper gluconate 1.0 % SEPPIC) Parfum / Fragrance 0.1 % KATHON CG (Methylchloroisothiazolinone and methylisothiazolinone 0.08 % distribué par SEPPIC) C Lactic acid 0.15 % Sodium chloride 0.8 % D Colorant / Dye 0.05 % E Sodium chloride Qs Procedure Mix phase A under extractor hood. Mix ingredients from phase B and introduce phase A into phase B. Add phase C and D. If necessary, the viscosity is increased with phase E (1.5% max). Comments PROTEOL APL MONTALINE C40 SEPITONIC M3 KATHON CG Fruit surfactant, derived from apple juice essential amino-acids, for a gentle approach : gentle approach for the touch, for the skin & the eyes and also for the environnement. Polyvalent quaternised coconut oil: foaming agent and extra-fluid thickening agents that is easy to use (it is incorporated at cold temperatures or at any step of the process). It is the ideal cosurfactant of sodium lauryl ether sulfate. It combats dryness and has also a dermo-protector effect. Multimineral chrono-energizer. Its zinc, copper and magnesium content helps stimulate the cells by increasing the energy profile (Pyruvate, ATP) and overall metabolism (DNA, proteins). Ideal for tired skin, SEPITONIC M3 delivers the elements needed for cell dynamism and the maintenance of skin function. It works to stimulate cell regeneration and helps restore fresh, radiant skin. Preservative. 18

1 % KATHON CG (Methylchloroisothiazolinone and methylisothiazolinone 0.08 % distribué par SEPPIC) C Lactic acid 0.15 % Sodium chloride 0.8 % D Colorant / Dye 0.

19 Characteristics Aspect clear and blue liquid ph around 6.0 Viscosity around 3,500 mpa.s / Brookfield LV2 6rpm Stability Stable at RT 40 C 4 C Notes Fragrance : Délice figue Ref RS12021 (TECHNICO FLOR) Dye: Bleu azur Ref W6004 (WACKHERR) 19

20 GENTLE SKINFEEL FOAM 6970 Formula A Sodium laureth sulfate % PROTEOL APL (Sodium cocoyl apple amino acids SEPPIC) 5.00 % SEPICIDE HB (Phenoxyethanol/Methylparaben/Ethylparaben /Propylparaben % /Butylparaben - SEPPIC) Parfum / Fragrance % Aqua / Water QSP 100 % SEPICIDE CI (Imidazolidinyl urea - SEPPIC) % B Lactic acid 0.15 % Procedure Add ingredients of phase A and mix well after addinf each of them. Then, add phase B. Comments PROTEOL APL Fruit surfactant, derived from apple juice essential amino-acids, for a gentle approach : gentle approach for the touch, for the skin & the eyes and also for the environnement. SEPICIDE HB - CI Preservatives Characteristics Aspect Clear colorless solution ph around 6 Viscosity < 50 mpa.s Brookfield LV 2 Stability Stable at RT / 40 C / 4 C Notes Fragrance : Délice Figue RS (TECHNICO FLOR) 20

15 % Procedure Add ingredients of phase A and mix well after addinf each of them. Then, add phase B.

21 Nota The analytical specifications warranted are only those mentioned on the certificate of analysis supplied with each delivery of the product. Except as set forth above, SEPPIC* makes no warranties, whether express, implied or statutory, as to the product which is the subject of this document. Without limiting the generality of the foregoing, SEPPIC* makes no warranty of merchantability of the product or of the fitness of the product for any particular purpose. Buyer assumes all risk and liability resulting from the use or sale of the product, whether singly or in combination with other goods. The information set forth herein is furnished free of charge and is based on technical data that SEPPIC* believes to be reliable. It is intended for use by persons having technical skill and at their own discretion and risk. Since conditions of use are outside SEPPIC*'s control, SEPPIC* makes no warranties, express or implied, and assumes no liability in connection with any use of this information. Nothing herein is to be taken as a license to operate under or a recommendation to infringe any patents. * SEPPIC being : and, depending on the country : SEPPIC S.A. SEPPIC UK Ltd SEPPIC ITALIA Srl 75, quai d Orsay 50 Salisbury Road Via Quarenghi Paris cedex 07 PO Box Hounslow Milano FRANCE TW4 6SH - ENGLAND ITALY Tel. : +33 (0) Tel. : Tel. : Fax : +33 (0) Fax : Fax : GIVAUDAN LAVIROTTE S.A. SEPPIC Inc. SEPPIC Chine 56, rue Paul Cazeneuve 30, Two Bridges Road, suite 210 Room 510 Jin Tai Building BP Lyon Fairfield, New Jersey South Mao Ming Road FRANCE USA Shanghai CHINA Tel. : +33 (0) Tel. : Tel. : +86 (21) Fax : +33(0) Fax : Fax : +86 (21) SEPPIC GmbH SEPPIC Belgium NV ABC Tower Köln Nieuwe Weg 1 Ettore - Bugatti - Str.6-14 Haven Köln-Porz B 2070 Zwijndrecht GERMANY BELGIUM Tel. : +49 (0) Tel. : Fax : +49 (0) Fax : Subsidiary of the AIR LIQUIDE group C/2582/GB/01/May

Microsoft Word _MONTANOV82_CH-simple.doc

Microsoft Word _MONTANOV82_CH-simple.doc MONTANOV 82 植物来源的糖苷乳化剂新型的非离子水包油糖苷乳化剂可乳化高含量的油相 ( 可乳化高达 50% 油相 ) 配方用量少, 可降低产品成本卓越的低温稳定性 (-25ºC), 特别适合北方寒冷地区耐电解质与各种防晒剂有良好的相容