1000022 1000145 P.2 P.7 P.13 99 1
99 1. 2. 3. 4. 2
1 1 1 2 2 3
3 3 3 7500 2009 4
1. 2. 3. 4. 5
1999 2002 1999 1999 1999 2005 2006 2007 2009 6
Common Cold A B C 8 8 7 11 11 9 A InfluenzaA B C 1 3AB C 7
H3? H3N2 H1? H1N1 H2N2 H1N1? 1889 1900 1918 1940 1960 1980 2000 1 A RNA 酶 2 13-7 AA1 H 16 酶 N 9 H NH Hemagglutinin N 酶 Neuraminidase2 酶 H1N11 8
酶 1H2N2H5N1 1 15 酶 1 9 A 25% A 112 3 (ILI Influenza-like Illness) 1 38 23 A 30A 4~5H1N1 8~9H1N1 9
(Tamiflu, oseltamivir)3 SARS HN H 2 N 3 Shikimic acid Oseltamivir phosphate 酶 AB 2-340% 48? 1. 2. 20 3. 4. 5. 6. 7. 8. 10
H1N1 SARS 疱 B NDM-1 11
C 1. H1N1 AB CD AE 2. H1N1AA 2 A H10N8 B H16N8 C H8N10 D H16N16 E H9N9 CD 3.2 A 16 酶 9 B 酶 C D 酶 E C 1. 2. AH N 3. A AH N B E AB 1. http://www.tafm.org.tw/ptwo/hi_articleview. aspx?hi_id=5 2.???http://kunghc.pixnet.net/blog/ post/25039105 3. http://www.babyhome.com.tw/mboard.php?op=d&sid=2095757&bid=6&r=2&pa ge=1 4. H1N1http://zh.wikipedia.org/zh-hk/%E7%94%B2%E5%9E% 8B%E6%B5%81%E6%84%9F%E7%97%85%E6%AF%92H1N1%E4%BA%9E%E5%9E%8B 5. (Tamiflu ) http://homepage8.seed.net.tw/web@5/famidoc/terms/tamiflu.htm 6. http://www.liverx.net/2009/05/01/%e5%85%8b%e6%b5%81%e6%84%9f/ 7. (2008-2009)H1N1http://misterclu.wordpress.com/2009/03/05/%E5%85%8B%E6% B5%81%E6%84%9F%E5%89%8B%E4%B8%8D%E4%BA%86h1n1%E6%B5%81%E6%84%9F/ 8. http://tw.myblog.yahoo.com/delightdetox/article?mid=22184 9. http://mulicia.pixnet.net/blog/post/3760111 10. - http://www.ttv.com.tw/lohas/green9272.htm 1. http://www.cdc.gov.tw/sp.asp?xdurl=disease/disease.asp&mp=1&ctnode=1498 1. http://zh.wikipedia.org/wiki/file:influenza_subtypes_hant.svg 12
F1 (1) F1 F2 (2) F1 F2 ( ) (3) F1F2 ( ) 13
(4) F1 F2 (5) F1 F2 40895105392 (6) X P P F1 X 3.8 ng/ml n/a 1.8 ng/ml n/a P F1 (1) =9:3:3:1 (2) =1:2:1 (3) =1:1:1:1 (4) =1:1 (5) 20 (6) X 1.8 ng/ml F1 R r S s (1) F1 9:3:3:1 (2) F1Rs rs Rs rs Rs RRss( ) RrSs( ) rs RrSs( ) rrss( ) (3) RrSs x rrss 1:1:1:1 14
(4) F1Rs rs rrss Rs rs rs Rrss( ) rrss( ) rs Rrss( ) rrss( ) (5) [(95+105)/(408+95+105+392)] x 100% = 20% (6) 15
活動大聲公 9/30 9/28 9/30 12/11 16