1 2 1 2 3 4 5 6 7 8 a- b- 9 10 11 R 12 13 NH2 COOH 14 N- C- 15 16 17 18 1. 2. 3. 4.a- 1
A B C D E 1( ) A B C D E 2 ( ) A B C D E 3 ( ) A B C ADP D 1 3 E 4 ( ) A IMP B AMP C GMP D XMP E ATP 5 SCOA ( ) A ACP B C D E A 6 ( ) A B C D E 7 ( ) A NADH FADH2 B GTP C COA D E 8 ( ) A HMG COA B HMG COA C HMG COA D COA E 9 ( ) A B C D E 3 10 DNA ( ) 2
A B C D E 11 ( ) A B C D E 12 ( ) A B C D E 13 ( ) A UAG B UAA C UGA D AUG E AGU 14 ( ) A B C D E 15 ( ) A B C D E 16 ( ) A B C D E 17 ( ) A B C D E 18 DNA ( ) A DNA B C DNA D DNA E DNA 19 ( ) A B C 6 3
D6 E 20 ( ) A B C D E 21( ) A B C D E 22 ( ) A B C D E 23 ( ) A G 1 P B G 6 P C UDPG D CDPG E GDPG 24( ) A B C D E 25( ) A B C D GTP E P 26 ( ) A DNA B DNA C DNA D RNA DNA E RNA DNA 27 ( ) A Km Vmax B Km Vmax C Km Vmax D Km Vmax E Km Vmax 28 ( ) A VLDL B CM C HDL D IDL E LDL 29 ( ) A 4
B Y C D Z E 30 ( ) A ATP B ADP C CTP D CDP E UDP 31 ( ) A 2 3 B 2 5 C 3 5 D E 32 ( ) A B C D E 33( ) A B C D E 34 ( ) A B C CO2 D E 35 ( ) A B C D E 36 ( ) A 1 B 2 C 3 D 4 E 5 1 (PI) PH>PI PH<PI 2 3 COA ATP 4 RNA 5 6 7 MRNA5 3 8 9 10 5
11 Ca 2 K 12 VitD 13 14 15 Watsan Crick bp 16 17 18 19 20 21 22 23 24 25 26 27 28 DNA 1 2 3 4 5 6 7 r 8 DNA 9 10 11 12 1 2? 3 4 5 6 6
1 E 2 D 3 B 4 A 5 B 6 B 7 D 8 C 9 D 10 B 11 D 12 B 13 D 14 D 15 B 16 E 17 E 18 D 19 D 20 C 21 A 22 C 23 C 24 D 25 E 26 C 27 A 28 A 29 C 30 D 31 C 32 C 33 D 34 C 35 D 36 C 1 2 CM VLDL LDL HDL 3 A 5 4 2 2 5 6 7 M7G POLYA 8 PAPS SAM PRPP 9 CH3 =CH2 CH= CHO CH=NH FH4 10 5r 11 12 1 25 (OH2)VitD3 13 CoA Fe2 14 15 10 16 17 18 Ca2 19 TPPFAD NAD CoASH 20 21 PH 22 VitD3 23 24 H K NaHCO3 25 NAD NADP FAD FMA Q 26 27 28DNA 1 ( ) 2 3 4 ADP ATP 7
5 H (2H=2e 2H ) H2O 6 A B C D E ( ) 7 r G SH r r 8 DNA DNA 9 DNA DNA DNA () 10 11 12 RNA 4SRNA RNA 4 dntp DNA ( ) 8
1 0 40g A 2 00g B 2 50g C 6 40g D 3 00g E 6 25g 2 A B C D E 3 A B C D E 4 A B C D biooo E 5 A B C D E 6 A ph pi B ph pi C ph pi D ph 7 4 E 7biooo A B C D E 8 A B C D E 9 pi 8 ph A 8 B 8 C 8 D 8 E 8 10 A B C D E 1 A B C D 2 9
A B C D 3 A B C D 4 - A 3 6 B C D R 5 A - B - C - D 6 - A B C D 7 A B C D 8 ph5 A pi 4 5 B pi 7 4 C pi 7 D pi 6 5 9 A B C D 10 A B C D 1 2 % 3 ph ph 4 5 6 7 10
8 10 10 1 B 2 E 3 D 4 B 5 E 6 C 7 D 8 D 9 B 10 E 1 AD 2 ACD 3 ABD 4 ABD 5 ABCD 6 ABC 7 BCD 8 BCD 9 AC 10 ABC 1 2 16 3 4 5 6 7 8 1 A C-5 B C-2 C C-3 D C-2 C-5 E C-2 C-3 2 A B C D E 3 RNA DNA A B C 11
D E 4 A 2 3 B C 2 5 D E 3 5 5 A 280nm B 260nm C 200nm D 340nm E 220nm 6 RNA A mrna B trna RNA C mrna D RNA mrna trna rrna E rrna 7 mrna 3 - A A B U C T D C E G 8 DNA A B C DNA D E DNA 9 DNA Tm A G+A B C+G C A+T D C+T E A+C 12
10 DNA 15% A 15% B 30% C 40% D 35% E 7% 1 DNA A A+C=G+T B C=G C A=T D C+G=A+T 2 A NAD+ B NADP+ C FAD D FMN 3 DNA A B C D 4 DNA A B DNA C DNA D DNA 5 DNA A B A-T G-C C D 6 trna A 3 A B 5 C-C-A 13
C D 7 DNA A B C D 8 mrna A B 3 - C D 5 C-C-A 9 Tm A Tm B DNA G C Tm C Tm D DNA A T Tm 10 DNA A B DNA C D - 1 2 RNA 3 4 5 ATP bcdp 6 RNA trna 14
7 trna 8 trna -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 15
1 A 2 D 3 A 4 E 5 B 6 C 7 A 8 D 9 B 10 D 1 ABC 2 ABC 3 AC 4 BD 5 ABCD 6 DE 7 AB 8 ABC 9 ABC 10 AC 1 2 3 9 1 4 camp cgmp 5 6 7 T C 8 1 A B C D E 2 A B C D E 3 A B C D E 4 A 16
B C D E 5 NADP+ B A B C D E 6 A B C D E 7 8 =1/2Km v Vmax A 0 25 B 0 33 C 0 50 D 0 67 E 0 75 8 A B C D E 9 ph A B C ph D E ph Km 10 A B 17
C D E 11 Km A B Vm C Km D 1/2Vm E 1 A B Vm C D Km 2 A B Vm C D Km 3 A B C D 4 FAD A B2 B C GMP D ADP 5 A B Km C D 6 18
A B C D 7 A B C D 8 A B C D 9 A ph B C D 10 A B C D 1 2 v Vm 80% [S] Km v Vm90% [S] Km 3 Km Km Km 4 Vm 5 Km 6 LDH LDH1 19
7 L- L- D- 8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 20
1 C 2 B 3 C 4 C 5 D 6 C 7 B 8 E 9 D 10 C 1 ABCD 2 BCD 3 BCD 4 ABD 5 AB 6 BCD 7 BCD 8 ACD 9 ABCD 10 AB 1 2 4 9 3 4 5 6 H M 5 7 8 1 mg/100ml A 60 100 B 60 120 C 70 110 D 80 120 E 100 120 2 A 6- B 6- C 1 6- D 3- E 1 3-3 A *** A B1 B B2 C B6 D PP E 21
4 A ADP B GDP C CDP D TDP E UDP 5 A B C D E 6 A B C D E 7 A B C-6- D E 8 A B 3- C D E 9 1 ATP A 1 B 2 C 3 D 4 E 5 10 22
A AMP B ADP C ATP D 2 6- E 1 6-11 ATP A B - C - D E 12 A A B C D A E 13 ATP A 2 B 2 C 2 D 2 E 2-14 A 1- B 6- C 1 6- D 3- E 6-15 A -6- B C D 6- E 23
1 A ATP B GTP C UTP D CTP 2 A 6- B NADH+H+ C NADPH+H+ D 5-3 1 A 3 CO2 B 15 ATP C 5 NAOH H2O D 4 A A+ B - C - A D A 5 A B C D 6 A B C D 7 A B C D 8 A FAD 24
B TPP C NAD+ D CoA 9 A B C D 10 A ATP B GTP C UTP D CTP 11 A B C D 12 A B 3- C D 13 A B C D 14 A B C D 15 A A B C 25
D 1 2 3 4 5 6 7 ATP 8 1 ATP 1 ATP -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 26
1 C 2 E 3 C 4 E 5 E 6 B 7 C 8 C 9 B 10 D 11 C 12 D 13 C 14 B 15 D 1 AC 2 CD 3 ABD 4 ABC 5 ABD 6 AC 7 AB 8 9 AB 10 AB 11 BCD 12 BC 13 BCD 14 ACD 15 ABCD 1 2 3 4 5 4 2 6 7 8 2 3 -- -- 1 A B C D E 2 Apo A B Apo A LCAT C Apo B LDL D Apo C E Apo C LPL 3 A CM VLDL IDL LDL B CM VLDL LDL HDL C VLDL CM LDL HDL D VLDL LDL IDL HDL E VLDL LDL HDL CM 4 27
A CM VLDL LDL HDL B VLDL LDL HDL CM C LDL HDL VLDL CM D HDL VLDL LDL CM E HDL LDL VLDL CM 5 A B C D E 6 A B C D E 7 A B C D E 8 A CoA B CoA C CoA D CoA FAD?2H NAD++H+ E H2O CO2 9 A B CoA C D HMG CoA E 10 A B 28
C D E 11 A B CoA NADPH+H+ C CoA D E CoA 12 A B 2- C 3- D E 13 A ATP CTP B NADPH+H+ C D E S- 14 A HMG CoA B HMG C HMG D HMG CoA E HMG 15 A B C D E D3 1 A B 29
C D 2 A B C D 3 A - B C D apob100 4 A CM B VLDL C IDL D LDL 5- A NADH+H+ B NADPH+H+ C FAD?2H D CoA 6 CoA A CO2 H2O B C D 7 CoA A B C D 8 A B C D 30
9 A CoA B NADPH+H+ C HMG CoA D HMG CoA 10 A B C D 11 A B C D 12 A - B C D S- 13 A2 A B - C D 14 A CoA B CoA C D LCAT 15 CoA A B C D 1 31
2 CoA CoA 3 4 - - 5 6 CoA 7 CoA 8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 32
1 B 2 D 3 B 4 D 5 D 6 E 7 D 8 E 9 C 10 E 11 E 12 D 13 B 14 D 15 C 1 CDE 2 BCD 3 AC 4 BD 5 ACD 6 ABD 7 ABCD 8 ABD 9 AC 10 ACD 11 ACD 12 ABC 13 A 14 CD 15 BD 1 2-3 LPL 4 1 CoA CoA 5 CoA CoA NADPH+H+ 6 7 8 - LCAT - ACAT 1 A GMP B AMP C IMP D ATP E GTP 2 A B C D E 3 A B 6 C 1 D 1 6 E 5 33
4 A B C D E 5 HGPRT- A B C D E 6 5Fu A B C D E 7 N C A B C D E 8 GMP C-2 A B C D E 9 dtmp A dump B TMP C TDP D dudp E dcmp 10-34
A CMP B AMP C TMP D UMP E IMP 11 A IMP B XMP GMP C UMP CMP D UMP dtmp E UTP CTP 1 A IMP B IMP GMP C UMP D dtmp 2 A CO2 B - C NH3 D 3 PRPP A IMP B IMP C GMP D UMP 4 A B C D 5 A B C D 35
6 A IMP B AMP C GMP D 7 6- A 6- IMP AMP B 6- IMP GMP C 6- D 6-8 A B C D 9 A 5- B C - D 10 A B C D 1 2 3 4 MTX 5 6 7 ATP GTP IMP AMP IMP 36
GMP -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 37
1 C 2 D 3 E 4 D 5 C 6 D 7 C 8 A 9 A 10 C 11 A 1 AD 2 ABC 3 ABCD 4 AD 5 ABC 6 ABC 7 ABC 8 ABC 9 ABC 10 AC 1 2 3 4 5 6-6MP 5-5-Fu 6 7 GTP ATP -- -- 1 A B - C -CoA D E - 2 A B C D E 3 A B C D E 4 A 38
B C- D E 5 A B C D E 6 A B C D E 7 camp A A B C D b E 8 camp A camp B camp C camp D camp E camp 9 A B C D E 10 camp A B C 39
D G GTP E 1 A B C D 2 A camp B DG C IP3 D cgmp 3 A B C D 4 A B C D 5 A B C D 6 A B C D 7 A b b B b b 40
C a D A 1 2 3 camp camp 4 A b 5 A C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 41
1 C 2 D 3 B 4 C 5 D 6 D 7 A 8 D 9 A 10 D 1 ABCD 2 ABCD 3 ABCD 4 ABC 5 AC 6 ABDC 7 BCD 1 2 IP3 DG 3 4 5 -- DNA -- 1 DNA A DNA DNA B DNA C D E 2 DNA A B C 5 3 D dntp E DNA 3 DNA 5 TAGA 3 A 5 TCTA 3 B 5 ATCA 3 C 5 UCUA 3 D 5 GCGA 3 E 5 TCTA 3 4 A DNA RNA B RNA DNA CDNA RNA 42
D DNARNA E RNADNA 5 DNA A DNA DNA B RNA RNA C DNA RNA D RNA RNA E DNA 6 DNA A 5 3 3 5 B 3 5 C 5 3 D E 7 A DNA DNA B RNA C DNA D DNA E DNA DNA 8 DNA A damp dgmp dcmp dtmp B datp dgtp dctp dttp C dadp dgdp dcdp dtdp D ATP GTP CTP UTP E AMP GMP CMP UMP 9 A DNA DNA B C RNA RNA D DNA RNA E RNA DNA 1 DNA 2 DNA 3 DNA DNA DNA 4 DNA A G 43
5 DNA DNA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 1 E 2 B 3 A 4 A 5 C 6 C 7 C 8 B 9 E 1 2 RNA 3 5 3 DNA DNA DNA 4 T C 5 DNA -- RNA -- 1 DNA 3 TGCAGT 5 RNA A 5 AGGUCA 3 B 5 ACGUCA 3 C 5 UCGUCU 3 D 5 ACGTCA 3 E 5 ACGUGT 3 2 RNA RNA A rrna B mrna C trna D 5SRNA E 18SRNA 3 RNA A B C D E 4 DNA RNA A DNA RNA 44
B RNA C RNA 5 3 D DNA RNA E RNA 5 DNA RNA A B C D E 6 A B C RNA D RNA E RNA 7 A RNA DNA RNA B DNA 5 3 3 5 RNA C DNA D E 8 DNA DNA A DNA DNA B 5 3 C D RNA E DNA RNA Mg2+ 9 RNA A B 2 C D E 1 DNA RNA 2 RNA 45
3 RNA 4 RNA DNA A T 5 RNA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- 1 B 2 B 3 D 4 B 5 A 6 C 7 A 8 D 9 C 1 RNA DNA RNA 2 2 2 3 4 U A 5 46