2005 002030 2006-005 2005 1 1.1 1.2 1.3 1.4 2005 1.5 2 2.1 002030 19

2005 19 510665 510665 http://www.daangene.com web@daangene.com 2.2 19 19 19 020-32290420 020-32290420 020-32290420 020-32290231 020-32290231 020-32290231 jswu@daangene.com yinchaochen@daangene.com jswu@daangene.com 3 3.1 2005 2004 2003 162,471,891.67 155,862,029.26 4.24% 132,490,092.40 32,170,999.45 30,047,923.65 7.07% 27,635,359.32 26,297,183.28 25,199,720.61 4.36% 23,093,300.55 19,503,732.93 16,947,331.08 15.08% 22,881,441.87 27,797,674.93 15,508,766.12 79.24% 22,917,407.20 2005 2004 2003 296,848,670.36 312,965,685.82-5.15% 176,425,066.31 268,113,394.88 256,165,672.60 4.66% 91,528,262.29 3.2 2005 2004 2003 0.31 0.30 3.33% 0.37 0.31 - - - 9.81% 9.84% -0.03% 25.23% 7.27% 6.62% 0.65% 24.89%

2005 0.33 0.19 73.68% 0.37 2005 2004 2003 3.21 3.06 4.90% 1.49 3.20 3.06 4.58% 1.44 : 0.00-53,362.19 0.00 8,045,949.16-1,199,136.62 6,793,450.35 3.3 4 4.1 +- 61,600,000 73.68% -6,600,000-6,600,000 55,000,000 65.79% 1 0 0.00% 0 0 0 0.00% 2 32,771,200 39.20% -3,511,200-3,511,200 29,260,000 35.00% 3 28,828,800 34.48% -3,088,800-3,088,800 25,740,000 30.79% 13,244,000 15.84% -1,419,000-1,419,000 11,825,000 14.14% 15,584,800 18.64% -1,669,800-1,669,800 13,915,000 16.65% 4 0 0.00% 0 0 0 0.00% 0 0.00% 0 0 0 0.00% 0 0.00% 0 0 0 0.00% 22,000,000 26.32% 6,600,000 6,600,000 28,600,000 34.21% 1 22,000,000 26.32% 6,600,000 6,600,000 28,600,000 34.21%

2005 2 0 0.00% 0 0 0 0.00% 3 0 0.00% 0 0 0 0.00% 4 0 0.00% 0 0 0 0.00% 83,600,000 100.00% 0 0 83,600,000 100.00% 20061117 18,755,000 36,225,000 47,375,000 5% 20071117 1,776,500 34,448,500 49,151,500 20081117 34,448,500 0 83,600,000 10 1 16,720,00020081117 16,720,000 2 12,540,00020081117 12,540,000 20061117 4,180,000 3 5,186,500 20071117 1,006,500 4 4,950,00020061117 418,000

2005 2007112 770,000 5 3,960,00020061117 3,960,000 6 352,00020061117 3,520,000 7 2,915,00020061117 2,915,000 8 2,024,00020081117 2,024,000 9 1,551,00020081117 1,551,000 10 1,122,00020081117 1,122,000 4.2 10 10 10,519 10 20.00% 16,720,000 16,720,000 0 15.00% 12,540,000 12,540,000 0 6.20% 5,186,500 5,186,500 0

2005 5.92% 4,950,000 4,950,000 0 4.74% 3,960,000 3,960,000 0 4.21% 3,520,000 3,520,000 0 3.49% 2,915,000 2,915,000 0 2.42% 2,024,000 2,024,000 0 1.86% 1,551,000 1,551,000 0 1.34% 1,122,000 1,122,000 0 10 600,000 557,377 364,266 345,000 210,483 172,100 169,000 148,006 127,400 125,650 4.3 4.3.1 4.3.2 2001 10 26 [2001]42 20% 1924 1926 135 3 "2 5

2005 6 3 8 5 3 20051231 591,412 184,806 406,606 4.3.3 5 5.1 53 20043212007 314 45 20043212007 314 48 20043152007 314 44 20043152007 314 43 20043152007 314 2,266,8802,024,000 29.45 0 0 0.00 0 0 0.00 0 0 0.00 0 0 0.00

2005 38 20043152007 314 45 20043152007 314 70 20043152007 314 47 20043152007 314 37 20043152007 314 50 20043152007 314 43 20043152007 314 39 20043152007 314 61 20043152007 315 40 20043152007 314 41 20053142007 314 30 20053142007 314 40 20043152007 314 36 20043212007 320 42 20053232007 320 43 20058172007 320 35 20043212007 320 1,256,6401,122,000 25.48 572,880 511,500 21.58 0 0 5.00 0 0 5.00 0 0 5.00 0 0 5.00 0 0 0.00 0 0 0.00 0 0 0.00 0 0 0.00 0 0 9.21 0 0 5.55 0 0 6.06 1,737,1201,551,000 21.58 0 0 19.76 0 0 23.57 0 0 18.01 - - - - 5,833,5205,208,500-200.25-6 6.1 1 2005

2005 PCR ISO17025 162,471,891.67 155,862,029.26 4.24% 87,612,852.24 83,506,646.69 4.92% 26,297,183.28 25,199,720.61 4.36% 2005 2 2000 PCR 863 PCR 200619 600 PCR PCR PCR

2005 6.2 16,247.19 7,152.31 55.98% 4.24% -0.64% 2.17% 9,621.30 2,030.44 78.90% 16.36% 21.03% -0.81% 1,752.85 1,249.06 28.74% -36.40% -42.44% 7.48% 4,555.98 3,627.24 20.39% 8.55% 13.44% -3.43% 317.06 245.57 22.55% -13.09% 60.30% -35.46% 6.3 6,360.55 30.10% 9,886.64 7.58% 6.4 14,817.99 3,014.13 7,115.92 % PCR 7,418.00 1,665.97 5,013.27 67.58% 312.9120068 7,392.00 1,348.16 2,102.65 26.49% 302.55-14,810.00 3,014.13 7,115.92-615.46 - - - -

2005 2005425 2004 2005126 2005 200619 2005 CNAL CNAL ISO/IEC17025:2005 1000 20051031 16,132,031.51 3000 2004729 GMP 600 GMP 2004 6 30 PCR 3704 660.00 616 2004823 3660 1 2005516 2005 4000 2005527 4000 200511

2005 2000 2000 20051115 22005126 2005 4000 20051229 4000 2004 6.5 200.00-476,294.77 100.00 192,426.91 100.00 77,001.03 400.00 - - 6.6 6.7 2005 26,297,183.28 10% 2,640,113.06 5% 1,320,056.54 31,917,025.45 12,540,000.00 41,714,039.13 20051231 8360 10 2.5 20,900,000.00 20,814,039.13 20051231 8,360 10 5 1 125,949,572.81 41,800,000 84,149,572.81 12,540

2005 6.8 8 8 0 0 8 0 0 8 0 0 7 1 0 8 0 0 8 0 0 8 0 0 8 0 0 8 0 0 7 1 0 8 0 0 7 7.1 7.2 7.3 7.4 7.4.1

2005 2.24 0.01% 0.00 0.00% 3.55 0.02% 0.00 0.00% 55.98 0.35% 0.00 0.00% 46.69 0.29% 0.00 0.00% 112.10 0.70% 0.00 0.00% 4.23 0.03% 0.00 0.00% 0.25 0.00% 0.00 0.00% 0.44 0.00% 0.00 0.00% 225.48 1.40% 0.00 0.00% 2.49 7.4.2 2006 7.5 7.6 7.6.1 1 1 2

2005 2005 2006 2007 50% 2005 2004 31,917,025.45 12,540,000 50% 3 2 3 7.6.2 7.7 8 2005 2 200615 2005 2005 2 12005323 19 7 7 2004 2004 2005 2004 2004 2004 22005817 19

2005 7 6 2005 2006 15 2005 2006123 2005 2005 PCR PCR 2005 PCR 16,659,696.32 13,481,631.37 2,846,760.73 395,477.80 165,360.00 10,074,032.84 2005126 2005 CNAL CNAL ISO/IEC17025:2005 1000 2006228 20051031 16,132,031.51 3000 200619 2005

2005 2005516 2005 4000 2005527 4000 200511 2000 20051115 2005126 2005 4000 20051229 4000 2004 2006 9 9.1 9.2 9.2.1 20051231 102,338,237.96 96,713,622.17 134,075,366.33 128,720,160.73 0.00 0.00 0.00 0.00 162,400.00 100,000.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 78,414,833.57 73,980,042.76 58,427,046.13 56,119,923.12 11,476,847.58 17,216,321.99 5,782,695.83 5,715,925.83 8,180,104.32 6,655,385.37 4,244,428.23 3,655,043.73 0.00 0.00 0.00 0.00 9,522,855.82 7,475,590.23 19,994,183.56 19,089,195.23 5,495.22 0.00 83,333.30 83,333.30 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 210,100,774.47 202,140,962.52 222,607,053.38 213,383,581.94

2005 761,852.62 5,970,903.95 0.00 8,327,345.32 0.00 0.00 0.00 0.00 761,852.62 5,970,903.95 0.00 8,327,345.32 207,347,316.18 202,747,019.87 185,003,585.20 182,193,000.20 124,827,961.66 123,919,552.97 94,644,952.76 94,376,605.65 82,519,354.52 78,827,466.90 90,358,632.44 87,816,394.55 0.00 0.00 0.00 0.00 82,519,354.52 78,827,466.90 90,358,632.44 87,816,394.55 0.00 0.00 0.00 0.00 3,466,688.75 3,466,688.75 0.00 0.00 0.00 0.00 0.00 0.00 85,986,043.27 82,294,155.65 90,358,632.44 87,816,394.55 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 296,848,670.36 290,406,022.12 312,965,685.82 309,527,321.81 0.00 0.00 35,000,000.00 35,000,000.00 0.00 0.00 0.00 0.00 5,523,168.82 4,225,706.77 4,286,838.45 3,173,874.45 293,860.22 219,696.50 173,041.02 173,041.02 0.00 0.00 0.00 0.00 10,882.46 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3,453,188.00 3,305,470.16 2,368,659.05 2,293,877.13 167,663.38 157,565.16 141,417.45 135,127.40 4,116,288.26 4,076,366.11 3,360,227.94 3,342,163.79 0.00 0.00 51,108.75 51,108.75 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 13,565,051.14 11,984,804.70 45,381,292.66 44,169,192.54 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 13,586,069.45 10,338,589.26 10,868,268.61 9,192,456.67 0.00 0.00 0.00 0.00 13,586,069.45 10,338,589.26 10,868,268.61 9,192,456.67

2005 0.00 0.00 0.00 0.00 27,151,120.59 22,323,393.96 56,249,561.27 53,361,649.21 1,584,154.89 0.00 550,451.95 0.00 83,600,000.00 83,600,000.00 83,600,000.00 83,600,000.00 0.00 0.00 0.00 0.00 83,600,000.00 83,600,000.00 83,600,000.00 83,600,000.00 125,949,572.81 125,949,572.81 127,759,033.81 127,759,033.81 16,849,782.94 16,829,575.83 12,889,613.34 12,889,613.34 6,093,407.11 6,086,671.40 4,773,350.57 4,773,350.57 41,714,039.13 41,703,479.52 31,917,025.45 31,917,025.45 0.00 0.00 12,540,000.00 12,540,000.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 268,113,394.88 268,082,628.16 256,165,672.60 256,165,672.60 296,848,670.36 290,406,022.12 312,965,685.82 309,527,321.81 9.2.2 20051 12 162,471,891.67 153,325,237.35 155,862,029.26 152,553,749.54 71,523,145.43 66,160,701.38 71,985,090.92 70,554,460.35 3,335,894.00 3,278,648.86 370,291.65 348,795.86 87,612,852.24-83,885,887.11 83,506,646.69 81,650,493.33 69,650.67-150,850.67 0.00 0.00 27,368,112.97 26,384,098.26 29,722,120.54 29,598,482.15 29,399,196.38 22,656,317.39 21,507,755.33 19,017,597.25-1,547,315.46-1,518,811.19 2,241,675.63 2,247,191.01 32,462,509.02-36,515,133.32 30,035,095.19 30,787,222.92-238,147.38 - -4,356,441.37 26,646.07-672,609.46 0.00 0.00 0.00 0.00 57,338.20 57,338.20 1,735.69 15,675.29 110,700.39 109,500.36 15,553.30 15,553.30 32,170,999.45-32,106,529.79 30,047,923.65 30,114,735.45 5,840,113.23 5,840,113.23 4,915,014.84 4,915,014.84

2005 33,702.94-66,811.80 0.00 0.00 0.00 0.00 0.00 26,297,183.28-26,266,416.56 25,199,720.61 25,199,720.61 31,917,025.45 31,917,025.45 19,737,262.93 19,737,262.93 0.00 0.00 0.00 0.00 58,214,208.73 58,183,442.01 44,936,983.54 44,936,983.54 2,640,113.06 2,626,641.66 2,519,972.06 2,519,972.06 1,320,056.54 1,313,320.83 1,259,986.03 1,259,986.03 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 54,254,039.13 54,243,479.52 41,157,025.45 41,157,025.45 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 12,540,000.00 12,540,000.00 9,240,000.00 9,240,000.00 0.00 0.00 0.00 0.00 41,714,039.13 41,703,479.52 31,917,025.45 31,917,025.45 1 0.00 0.00 0.00 0.00 2 0.00 0.00 0.00 0.00 3 0.00 0.00 0.00 0.00 4 0.00 0.00 0.00 0.00 5 0.00 0.00 0.00 0.00 6 0.00 0.00 0.00 0.00 9.2.3 20051 12

2005 152,342,973.53 144,443,850.12 0.00 0.00 22,189,163.64 24,293,077.09 174,532,137.17 168,736,927.21 48,022,355.76 40,086,252.87 24,946,143.44 19,722,439.45 19,680,583.92 18,975,536.96 54,085,379.12 62,214,144.50 146,734,462.24 140,998,373.78 27,797,674.93 27,738,553.43 800,000.00 800,000.00 0.00 0.00 115,000.00 115,000.00 0.00 0.00 915,000.00 915,000.00 14,158,260.20 12,368,548.89 1,000,000.00 2,800,000.00 0.00 0.00 15,158,260.20 15,168,548.89-14,243,260.20-14,253,548.89 200,000.00 0.00 92,000,000.00 92,000,000.00 1,769,292.84 1,769,292.84 93,969,292.84 93,769,292.84 127,000,000.00 127,000,000.00 12,256,655.94 12,256,655.94 4,180.00 4,180.00 139,260,835.94 139,260,835.94-45,291,543.10-45,491,543.10 0.00 0.00-31,737,128.37-32,006,538.56 1 26,297,183.28 26,266,416.56 816,488.31 814,938.90 30,311,015.04 29,670,953.46 0.00 0.00 0.00 0.00 77,838.08 83,333.30-51,108.75-51,108.75 75,205.01 75,205.01 0.00 0.00

2005 775,796.25 775,796.25 238,147.38 4,356,441.37 0.00 0.00 10,471,327.74 11,613,605.00-42,746,476.23-39,344,647.46 9,310,930.45 2,866,720.91-7,812,374.57-9,389,101.12 33,702.94 27,797,674.93 27,738,553.43 2 0.00 0.00 0.00 0.00 0.00 0.00 3 102,338,237.96 96,713,622.17 134,075,366.33 128,720,160.73 0.00 0.00 0.00 0.00-31,737,128.37-32,006,538.56 9.3 2005817 200511 1 (1) (2) (3) 3 2 1 0.5% 1 2 10%2 3 15%3 40% 100% 1 (1) (2) 3 2 1 0.5%1 2 10%2 3 15%3 40% 100%

2005 9.4 9.5 2005430