2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 : 1006 2 446X (2008) 02 2 00152 17. (, 201800) :,, ;, : ; ; ; ; : R 15313 : A, () () ( ) () () () [ 1 ],, 1,, ( ) 1996 1997, 4 ( ), 12 42 [ 2 ], (1) 1, 36, 17 50 %, 17 115,,,, 92 %,,,,,,, : 2007 2 12 2 01 15
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 1 : g/ d a : b : a/ b Ag 30160 510 41 08 As 138100 50100 11 84 Au 0123 015 01 45 Cd 75160 1525 31 78 Ce 18170 < 15 Co 37100 2010 11 85 Cr 175100 50 31 50 Cs 13100 10 11 30 Eu 0157 Hg 34150 10 31 45 I 364100 200 11 82 In 58100 Li 72120 30100 11 11 La 22160 Mo 300100 200 11 50 Ni 274100 170400 01 96 Pb 392100 50100 51 23 Sb 11180 5 21 36 Sc 3199 < 0155 Se 52170 150 01 35 Th 5135 11 15 41 65 U 6175 11 27 51 31 V 490100 10 49100 Y 40100 Zr 209100 < 5 Al B Ba Br Ca Cu F Fe Mg Mn Rb Sr Ti Zn Cl K Na P 201 00 10 3 101 0 10 3 21 00 21 12 10 3 118 10 3 11 18 01 66 10 3 016 10 3 11 10 21 20 10 3 410 10 3 01 55 7231 00 10 3 1 100 10 3 01 66 11 60 10 3 115 10 3 11 07 11 73 10 3 210 10 3 01 87 301 50 10 3 16 10 3 11 91 3571 00 10 3 340 10 3 11 05 61 82 10 3 410 10 3 11 71 31 40 10 3 218 10 3 11 21 21 86 10 3 115 10 3 11 91 21 30 10 3 0180 10 3 21 88 121 40 10 3 13 10 3 01 96 71 56 10 6 512 10 6 11 45 21 11 10 6 313 10 6 01 64 31 64 10 6 414 10 6 01 83 01 95 10 6 114 10 6 01 68 16
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 2,,,,, 9213 %100 % 211 4, : (1) (2), (2) (3), (3) (4), (4) (5) 2 p H [3 ] p H 71 5 71 3 71 9 71 4 71 6 81 0 71 8 3 [3 ] 45 37 28 31 49 129 250 480 4 [4 ] : Hz 17 O 2 NMR 127 () 122 119 118 17
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 4 () 17 O 2 NMR 105 94 76 M 2 67 109 132 135 74 68 110130 119 68 5312 11 9 77 2 89 63 66 : : 17 O 2 NMR 100 Hz, 5060 Hz ; M 2 : 5 [3 2 5 ] : mg/ L 18 K 161 40 2183 1110 Na 161 00 0155 3100 Ca 951 50 42190 24105 Mg 541 50 2140 3104 Li 01 30 0137 < 0102 Rb 01 47 0124 Sr 21 41 0130 0110 Se ND 0181 < 01 005 Cs ND 1183 Ba 01 06 0104 In ND 0105 B 01 44 0103
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 5 () Ge 0105 01 005 Sn 0104 01 110 Sb ND 01 150 Bi 01044 01 290 Fe 01024 01 078 Co ND 01 141 Ni ND 01 077 Cu 01011 01 015 Cr 01013 01 064 Ag 01032 01 009 Mo 01019 01 113 W ND 01 195 Al 01103 01 061 0103 Pb 01079 01 493 < 0101 As ND 01 119 < 0101 Cd ND 01 009 < 01 005 Hg ND 01 058 < 01 001 18178 201 520 14156 2140 01 147 0142 : ND,, ( 5), (6), [ 6 ] 6 9 610, 9 89, 17 O 2 NMR 53189 Hz,, 81 67 mg/ L p H 81 0, 3 19
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 212, d,, [7 ],, (7) [7 2 8 ], 10, Mn 2 + Mo 2 + Zn 2 + V 2 + Cr 3 + Fe 2 + Co 2 + Cu 2 + Ni 2 + Sr 2 +, 7 3 + Ti ( H2 O) 6 3 + V ( H2 O) 6 3 + Cr ( H2 O) 6 3 + Mn ( H2 O) 6 3 + Fe ( H2 O) 6 2 + Co ( H2 O) 6 2 + Ni ( H2 O) 6 2 + Cu ( H2 O) 6 1 1173 2 2183 3 3187 4 4190 5 5192 3 3187 2 2183 1 1173 213, (1), (nm),, ( 17 O NM K 100 Hz) (8),,, DNA,, (2) (3) 8 : nm Rb + Cs + Ti + 0125 K + Br 2 I 2 0130 F 2 0135 Sr 2 + 0150 Li + 0160 Ca 2 + Cu 2 + Zn 2 + Mn 2 + Fe 2 + Ni 2 + Co 2 + 0160 Mg 2 + 0183 Fe 3 + Cr 3 + Se 4 + 0190 20
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 21
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 22
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 3,, [5 ],,, [3 ], 311, (9), 100 90 (10) 90 89 (11) (12) 9 : g/ g [9 ] [10 ] [11 ] [12 ] [13 ] [14 ] [15 ] Cd 0111 0119 0101 Cu 12133 8195 9183 81 30 7109 10120 8150 Cr 0134 0133 0136 21 40 Zn 156100 145100 162100 1801 00 184100 119100 117100 Fe 23110 69100 42100 891 60 21160 Mn 9156 2161 1135 41 40 3136 5158 3130 Ni 0127 0114 1117 Sr 3172 4107 4104 2114 Se 0139 0175 0130 21 20 0171 Ca 1 066100 403100 5461 00 994100 556100 452100 Mg 110100 781 00 F 0158 Pb 6140 5165 5105 Mo 0108 1195 Co 0109 01 30 V 0111 01 03 Hg 1116 Sb 0111 01 10 Sc 0101 01 20 As 0161 01 30 K 42170 221 00 I 0159 11 20 Al 18145 191 50 11190 21180 25110 Cl 3 264100 1 7761 00 : 23
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 10 : g/ g [10 ] [11 ] [15 ] Cu 8195 14139 9183 15156 8150 91 75 Zn 145100 165100 162100 152100 117100 1241 00 Mn 2161 2152 1135 2116 3130 41 34 Cr 0134 0142 0136 0135 Fe 69100 50110 42100 57170 Se 0175 0162 0130 0128 Ca 403100 550100 452100 417100 Al 18150 21160 25110 241 40 K 42170 49110 Hg 1116 1118 As 0161 0173 Ni 0114 0114 Sr 2114 21 33 : 11 [16 ] : g/ g Zn Cu Fe Mn Sr Cr Ca Mg 189100 57100 (7) 1781 00 46100 (4) 81 88 2130 (7) 8189 2120 (4) 291 40 18150 (5) 24180 121 20 (4) 31 26 2192 (6) 2166 1183 (4) 41 04 3195 (3) 1149 1157 (3) 01 34 0121 (3) 1159 11 15 (2) 8541 00 3761 00 (2) 637100 327100 (3) 114100 62100 (1) 78150 301 80 (3) : 90, 6089 ; ( ) 12 [9 ] Fe 11 07 0179 1198 1143 1123 0139 Mg 21 14 4196 0186 0170 0189 0176 Cu 11 13 0180 0180 0164 0197 0193 24
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 12 () Zn 11 09 3154 11 05 0155 1101 01 99 Se 01 85 1112 21 04 2128 3140 01 98 Mn 01 85 3180 01 89 0148 1101 01 61 Sr 21 68 2136 01 96 0182 0150 01 82 F 11 34 2110 11 05 1198 > 01 98 Cr 01 96 0198 11 14 0188 0193 11 31 Mo 11 45 1124 01 89 1132 1159 11 09 Co 11 03 0196 01 50 0138 4130 01 98 Ni 11 20 1114 01 95 0173 0186 11 25 V 11 07 1100 01 99 1116 1132 11 22 Ca 2128 01 87 0182 1117 01 77 Cd 2106 01 77 0168 0186 11 10 Pb 1123 01 45 0177 11 66 / % 9610 9612 9715 9312 10010 7614 : : g/ g, g/ L ; ; >, ;,,,,,,,, 9497, 90100 [16 ] 312 80,, : 1982,, [17 ] ; 1983,,, ( 12) ; 1984, 26, [18 ], [19 ],, 90,,,,, [20 2 22 ], 90,, 90 25
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 (13), [23 ] 313 13 90 ( n = 339) ( P) B 01244 < 01 01 F 01198 < 01 01 Se 01337 < 01 01 Fe 201020 > 01 05 Mn 01065 > 01 05 Cu 01091 > 01 05 Zn 01199 < 01 01 Ni 01224 < 01 01 Co 201121 < 01 05,,,, 246 d,, 160180 d,, 90 d, 3 [ 24 ], (8610 ), (160 d), (8631 ), 246 d 8631 (8632 ), 246 d, (510 10 2 6 ) 3180 d (14),, 8631 8632 [19 ] 14 8610 MnMo SeSr ZnCo Cr 3 + 3 8611 8610 Ca Mg 90 8620 8610 CuCd 0 8630 8631 Mg 180 8631 MnMo SeSr ZnF 246 8632 8631 Ca Mg 246 8640 8631 Pb 30 8650 8631 Cd 3 60 : d : 8610 8610, ; 8610, 8631 ; 26 86318632 246 d, 01 1 10 2 6 2 110 10 2 6 120 180 d
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 (8631 ) (8632 ) ( 15) 7812 %, 4416 % ; 6715 %, 4318 % 2815 %, 4215 % 15 : d 601 0 24610 261 1 4615 5610 811 0 341 5 5718 6410 921 0 3761 0 48310 59710 8511 0 4,,,, 411 ( TC) 6569, 2 ( HDL 2 C) A POA 2 1, A POB (16), [26 ], ( T G) [27 ] 412 ( GSH 2 Px) (SOD), 6590 [28 ], 60 ( 17) GSH 2 Px SOD 18 45 [29 ],, (18) 16 ( n = 26) ( n = 37) TC / (mmol/ L) T G / (mmol/ L) HDL 2 C / (mmol/ L) A POA 2 1 / (g/ L) A POB 2 1 / (g/ L) 3139 0145 3140 0146 11 32 01 41 3 1110 0150 11 38 01 14 3 1126 0115 11 48 01 37 3 1121 0121 01 94 01 23 3 1114 0123 :, 3 P < 01 05 27
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 17 GSH 2 Px / (mol/ L) SOD / (mg/ L) 44 72127 4154 65118 19187 39 68139 5112 65140 20141 47 61118 9180 3 54150 18185 3 47 60150 7174 3 54131 20136 3 : 6590, 60, 60 ;, 3 P < 0105 18 GSH 2 Px / (mol/ L) SOD / (mg/ L) 82 122130 321 93 3 3 61182 26123 3 56 131175 331 14 64186 26113 26 101194 321 47 55172 26104 60 461 90 32147 51180 6196 :, 3 P < 0105 ; 3 3 P < 01 01 ;, P < 01 01, (L PO), (MDA), L PO (19) 19 L PO / (mol/ L) MDA / (mol/ L) [28 ] 44 3182 1181 3 3 39 3186 1145 47 5177 2113 47 6165 2101 [29 ] 82 4139 1115 3 3 56 3179 1109 26 5168 1127 60 3116 0190 [30 ] 29 3196 0158 3 3 23 5106 1102 :, 3 3 P < 0101 ( ) 28
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 413,, [31 ],,, 30 d,, 8670 8680,, (20) HDL 32 C [ (0173 0108) mmol/ L ] [ (0150 0105) mmol/ L ], [ (0198 0113) mmol/ L ] [ (1111 0113) mmol/ L ] 414, (21),,SOD [ (2 024 290) u/ g Hb ] [ (1 686 297) u/ g Hb ], L PO [ (2912 317) nmol/ L ] [ (4613 616) nmol/ L ], L PF [ (5135 0199) u/ g ] [ (8153 1122) u/ g ],,, 20 : mmol/ L HDL 32 C 8610 MnMo SeSr ZnCo Cr 3 + 01 66 0148 0183 8611 8610 Ca Mg 01 59 0144 0170 8631 MnMo SeFSr Zn 01 61 0150 0167 8632 8631 Ca Mg 01 74 0149 0170 8660 MnMo Sr V FCo Cu 01 66 0158 0178 8661 8660 Ca Mg 01 58 0140 0167 8670 MnMo Se YPdGe 01 58 0173 3 3 0167 3 8680 8670 Ca Mg 01 67 0173 3 3 0154 01 69 0150 0173 : 8610 8610, ;, 3 P < 01 05, 3 3 P < 0101 21 SOD / (u/ g Hb) L PO / (nmol/ L) L PF / (u/ g) 8610 1 934 2114 3 3 4119 3 3 8611 1 736 2017 3 3 4103 3 3 8631 2 356 3 3 3117 3 3 4101 3 3 8632 2 024 3 3 2912 3 3 5135 3 3 29
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 21 () SOD / (u/ g Hb) L PO / (nmol/ L) L PF / (u/ g) 8660 1 796 3215 3 3 4149 3 3 8661 2 288 3 3 3415 3 3 6114 3 3 8670 2 323 3 3 3810 3 3 7156 3 3 8680 2 035 3 3 3517 3 3 7136 3 1 686 4613 8153 : 20 ;, 3 P < 0105, 3 3 P < 0101 5, (1), (2) (3) ( ) (4), (5) : [1 ].. [J ]., 2007, 14 (11) : 23 2 39. [2 ],,,. [J ]., 2000, 20 (6) : 378 2 384. [3 ], 1 [ M ]. :, 2005 : 1 2 227. [4 ].,? [ M ]. :, 2007 : 103 2 108. [5 ] 1 [ EB/ OL ]. http : www. bama1 gov1cn. [6 ]., [ N ]., 2007 2 03 2 13 (11). [7 ],,. () [J ]. 2, 2003, 5 (4) : 11 2 15. [8 ]. [ M ] 2.. 2000. [9 ],,,. [J ]., 1986, 5 (2) : 72 2 77. [10 ],,,. [J ]., 1987 (3) : 24 2 29. [11 ],,,. 113 [J ]., 1990, 13 (3) : 178 2 180. [12 ],,,. [J ]., 1995, 14 (5) : 309 2 310. 30
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 [13 ],,,. [J ]., 1996, 3 (2) : 46 2 48. [14 ],,,. 2 2 ICP 2 A ES [J ]., 2002, 21 (3) : 61 2 63. [15 ],,,. [J ]., 2002, 19 (2) : 12 2 15. [16 ],, 1 [ M ]. :, 2003 : 204 2 220. [17 ],. [J ]., 1986, 3 (2) : 3102314. [18 ], 1 [J ]., 1985, 5 (4) : 528 2 532. [19 ],,,. [J ]., 1997, 3 (2) : 52 2 55, 70. [20 ],,,. 8097 10 [J ]., 2001, 8 (3) : 25 2 28. [21 ],,,. [J ]., 1999, 16 (2) : 61 2 63. [22 ], 1 19 [J ]., 1999, 16 (4) : 45 2 47. [23 ],,,. [J ]., 2005, 42 (5) : 753 2 760. [24 ],,,. [J ]., 1995, 2 : 1 2 6. [25 ],,,. () [J ]., 2003, 9 (4) : 246 2 247. [26 ], 1 [J ]., 1999, 18 (6) : 356. [27 ],,,. () [J ]., 2003, 9 (2) : 118 2 121. [28 ],. GSH 2 PxSOD L PO [J ]., 1999, 5 (1) : 35 2 36. [29 ],,. [J ]., 1998, 17 (3) : 183. [30 ],,,. [J ]., 1994, 14 (6) : 331 2 333. [31 ],,,. [J ]., 1991, 10 (2) : 99 2 103. 31
2008 GUANGDONG WEILIANG YUANSU KEXUE 15 2 Study on Chinaπs Senior Residents Aged at and above 100 Years Old. Trace Element s Essential Material Base of Longevity Q IN J unfa ( shanghai Institute of Applied Physics, Chinese Academy of Sciences, shanghai 201800, China) Abstract : The statistics of t he epidemiology researches of Chinaπs senior resident s aged at and above 100 years old and ot her experimental st udres were conducted. The result s show that trace element s play an role in t he formation of longevity. There are rich traee element s existing in the form of water2complex ion in t he drinking water of t he loglongeniy region. There also exist sa supreme trace elemeut spectrum in t he natural environment and inside human bodies. These trace element s can adjust metabolism of lipid, decrease t he damage by self2oxidation and prolong the longevity of peook. Therefore, trace element s form a most important mterral base for peopleπs longevity. Key words : China ; seniors aged at and above 100 years old ; trace element ; water2complex ion ; trace element s spectrum 1994,, : CN44 2 1396/ T, : ISSN 1006 2 446X, (CA) () ( ) 15,,,, 15,, 10, 120 : 100 : 510070 : : : : 3602001009003227055 32