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1 REGENT PACIFIC GROUP LIMITED 0575 PLETHORA SOLUTIONS HOLDINGS PLC 26 EGM-1 EGM-3

2 Plethora Jamie Gibson Plethora i

3 ... I-1... II-1... III-1... IV-1 Plethora... V-1... VI-1... VII-1 Plethora... VIII-1... IX-1... X-1 Plethora... XI-1... EGM-1 ii

4 Catalent Catalent Pharma Solutions, LLC Catalent, Inc. CfE Capital for Enterprise Fund A L.P. CfE Plethora Capital for Enterprise Fund A L.P. Plethora Plethora 1 Plethora Plethora Plethora Plethora 3% 32,471,058 Plethora 1

5 Plethora Plethora Anthony Baillieu Greg Bailey A 14,047,113,239 (i) (ii)plethora CREST Euroclear CREST CREST SI

6 8 James Mellon Jayne Sutcliffe Anderson Whamond ,933,006 Plethora (i)plethora (ii) Plethora (iii) (iv)plethora (i) (ii) EGM-1 EGM-3 Plethora Euroclear Euroclear UK & Ireland Limited

7 Plethora EGM-1 EGM-3 VI Plethora 2.7 Plethora Plethora Galloway Plethora Galloway LimitedJames Mellon Plethora 1.25 Plethora Plethora Plethora Plethora 5% 54,118,431 Plethora 4

8 Herax Partners LLP Herax Partners LLP 3 Plethora David Comba Julie Oates Plethora Michael G Wyllie David Comba Julie Oates Jamie GibsonMark SearleAnthony Baillieu Greg Bailey JM Plethora 5

9 Plethora 1,000,000 (i) (ii)plethora London Stock Exchange plc 28 Plethora Plethora 8 6

10 Plethora Plethora Plethora Pharmaserve Pharmaserve (North West) Ltd Plethora Plethora Solutions Holdings plc Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Solutions Holdings plc Plethora Plethora Plethora Plethora Plethora Solutions Holdings plc Plethora Plethora 7

11 Plethora Plethora Plethora Plethora 1 Plethora Plethora PSD502 TM Plethora PSD502 TM Recordati Recordati Ireland Ltd Recordati S.p.A (i) (ii) 112 Plethora Plethora 26 Plethora 8

12 899 Plethora Plethora (i) Plethora (ii) Plethora (iii) Plethora

13 548 20% Plethora Plethora Plethora Plethora Plethora Plethora VI 10

14 Plethora Plethora Plethora Plethora (i) (ii) (iii) (iv)

15 * ** Plethora Plethora Plethora CREST Plethora Plethora Plethora * (i) (ii) (iii) 112 ** Plethora 12

16 REGENT PACIFIC GROUP LIMITED 0575 Jamie Gibson P.O. Box 309 Ugland House Grand Cayman James Mellon KY Stephen Dattels Cayman Islands David Comba # Julie Oates # Mark Searle # Jayne Sutcliffe 5 8 # PLETHORA SOLUTIONS HOLDINGS PLC 26 1 Plethora Plethora 13

17 Plethora Plethora Plethora 26 Plethora A Jamie GibsonMark Searle Anthony Baillieu Greg Bailey David Comba Julie Oates 2 (a) (b) Plethora Solutions Holdings plc 14

18 (c) Plethora (o) Plethora Plethora (d) 26 Plethora Plethora Plethora Plethora Plethora (e) Plethora Plethora Plethora Plethora Plethora Plethora 14,047,113, % 403% 14.02% Plethora Plethora Plethora Plethora 15

19 0.069 Plethora Plethora 80,780, ,560, ,230,000 Plethora 96,270, ,530,000 1,063,320,000 Plethora Plethora % Plethora % Plethora % Plethora Plethora 102,900, ,500,000 1,228,400,000 Plethora 122,600, ,800,000 1,463,300,000 Plethora Plethora % Plethora % 16

20 Plethora % (f) Plethora (i) Plethora Plethora Plethora 75% (ii) Plethora Plethora Plethora Plethora (iii) Plethora (iv) Plethora (v) (vi) (i) (vi) 17

21 112 Plethora Plethora Plethora Plethora Plethora 19.14% Plethora Plethora Plethora Plethora (g) Plethora Plethora 18

22 Plethora (f) Plethora Plethora Plethora 112 Plethora (h) (i) Plethora Plethora Plethora Plethora 150,000 19

23 100,000 (ii) Plethora Plethora 12 (iii) Plethora Plethora 1,000,000 Plethora PSD502 TM Plethora 5% 360 (i) Plethora Plethora Plethora 10.54% James Mellon 18.87% Jamie Gibson Plethora 20

24 PSD502 TM Recordati PSD502 PSD502 PSD502 Jamie Gibson Plethora Plethora Michael G Wyllie Plethora PSD502 PSD502 Plethora PSD502 TM Plethora Plethora Plethora PRO PE PEBEQPRO PDUFA (Prescription Drug User Fee Act) 10 21

25 Plethora (i) (ii) (iii) (iv) (v) Plethora Plethora RecordatiPlethora Plethora PSD502 TM Plethora PSD502 Plethora PSD502 Plethora Plethora Plethora Plethora Solutions Limited Plethora Plethora PSD502 22

26 10,000,000 7,050,000 77,880,000 Plethora Plethora Solutions Limited PSD502 Plethora Sharwood Limited Plethora Sharwood Limited 2,400,000 3,600,000 28,100,000 Plethora 4,600,000 7,000,000 53,900,000 4,600,000 7,000,000 53,900,000 Plethora Plethora 2,540, , , ,000,000 56,670,000 80,370,000 (j) Plethora Plethora (i) Plethora Plethora Michael G Wyllie (i) (ii) Plethora Plethora James Mellon Plethora Jamie Gibson Plethora Greg Bailey Anthony Baillieu 244,413,861 Plethora Plethora 29.69% 23

27 (ii) Plethora Plethora 560, ,000 6,190,000 Plethora Plethora Plethora 1,000,000 1,420,000 11,050,000 Plethora 500, ,000 5,520, , ,000 4,200, , ,000 5,520, Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora PSD502 TM PSD502 TM PSD502 TM Recordati Plethora Plethora Plethora 10,000,000 7,050,000 77,880,000 Plethora 24

28 Plethora Solutions Limited Plethora PSD502 TM Plethora 12 (iii) Plethora % Plethora Plethora 9 Plethora Plethora I 8 Plethora Plethora ,952,150 56,670,

29 Plethora Plethora Plethora Plethora Plethora I 8 Plethora (iv) Michael G Wyllie Plethora Michael G Wyllie Michael G Wyllie PSD502 TM Plethora Plethora (v) Plethora Plethora Plethora Jamie Gibson Michael G Wyllie (vi) Plethora Plethora Plethora 26

30 Plethora Plethora Plethora (k) Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora (l) (l) Plethora 1,759,127 Plethora Plethora 0.21% Plethora Plethora 0.24% Plethora Plethora Forest Nominees Limited Canaccord Genuity Wealth (International) Ltd W B Nominees LimitedWalker Crips Stockbrokers Limited 85,652,633 Plethora Plethora 10.40% Plethora Plethora 11.63% Plethora Plethora 87,411,760 Plethora Plethora 10.62% Plethora Plethora 11.87% 27

31 (m) Plethora PSD502 Plethora Michael G Wyllie Plethora Michael G Wyllie Michael G Wyllie PSD502 James MellonAnthony Baillieu Greg Bailey Plethora Michael G Wyllie Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Jamie GibsonPlethora James MellonPlethora Plethora 28

32 (n) Plethora 823,297,686 Plethora 86,799,490 Plethora 1,700,000 Plethora Mark Searle 155,358,771 Plethora James Mellon 555,600 Plethora Greg Bailey Plethora 29.69% Jayne Sutcliffe Anderson Whamond Anthony Baillieu Plethora (o) Plethora Plethora Plethora Plethora (i) James Mellon Plethora 340,000 5% James Mellon Plethora 2 Plethora Plethora 17,000,000 Plethora James MellonJM (ii) Plethora Galloway LimitedJames Mellon Plethora 1.25 Plethora Plethora Plethora Plethora 5% 54,118,431 Plethora Galloway (iii) Plethora Capital for Enterprise Fund A L.P. Plethora Plethora 1 Plethora Plethora Plethora 3% Plethora 32,471,058 Plethora CfE 29

33 (iv) Plethora 101,148, Plethora 12,649,745 (i) (iv) Plethora Plethora Plethora Plethora (i) Jamie Gibson 35,000,000 Plethora (ii)james Mellon 1,000,000 Plethora (iii) Greg Bailey 1,000,000 Plethora (iv) Michael Collis 1,000,000 Plethora (v) Michael G Wyllie 16,000,000 Plethora Plethora Plethora 200,000 Plethora Michael G Wyllie Plethora 111,476 Plethora Plethora 59 Plethora 20,984 Plethora Plethora 59 Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora 14 30

34 JM James Mellon Plethora JM JM Plethora 267,029,200 James Mellon JM Plethora 17,000,000 Plethora James Mellon JM 16, ,884 Galloway Galloway Limited Galloway Galloway Limited Galloway Plethora Galloway Plethora Galloway Limited Galloway Plethora ,738,472 Galloway Limited Galloway CfE CfE CfE CfE CfE CfE CfE CfE CfE Plethora CfE Plethora CfE CfE Plethora ,042,938 CfE CfE CfE Plethora CfE CfE Plethora CfE CfE Plethora 31

35 Plethora Plethora Plethora Plethora Plethora 30 Plethora Plethora (i) Plethora (ii) Plethora (iii) Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora 100% 32

36 (p) Plethora Plethora Plethora Plethora Plethora Plethora Plethora 90% 90% 50% Plethora Plethora 33

37 (q) Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora CREST Plethora Plethora Plethora Plethora (r) Plethora Plethora Plethora 12 Plethora A 34

38 3 (i) Plethora (ii) Plethora Plethora % (iii) Plethora Plethora 41.07% FactSet Plethora 100% Plethora (i) 1,104,000 1,565,693 12,193,929 (ii) 15,734,000 25,920, ,981,000 (iii) 8,755,000 13,700, ,265, Plethora Plethora 114, ,675 1,259,156 2,857,000 4,451,000 34,513,

39 4 5 3,485,730, % (%) (%) James Mellon 15.35% 23.43% James Mellon 17.05% 23.77% 29.50% 29.53% Plethora Michael G Wyllie 1.59% Anthony Baillieu Greg Bailey Plethora % 0.14% Baker Brothers Advisors 5.00% Maven Capital Partners UK LLP 7.97% 70.49% 55.77% 36

40 Plethora Plethora Plethora Plethora Plethora 11,568,619,063 Plethora Plethora Plethora Plethora 2,478,494,176 Plethora Jamie GibsonMark SearleAnthony Baillieu Greg Bailey 6 Plethora Plethora 37

41 Plethora Plethora 49,200,000 34,690,000 Plethora 180, , ,800, ,470,000 PSD502 TM 171,900,000 Plethora PSD502 TM 8,560,000 6,040,000 Plethora Plethora 15,690,000 22,250,000 68,630,000 48,390,000 Plethora Plethora 10,180,000 PSD502 TM 19,350,000 Plethora (i) 10,180,000 Plethora (ii) Plethora 25,800,000 Plethora 25,800,000 Plethora Plethora 38

42 Plethora Plethora 14,047,113,239 1,209,770, ,530, ,330,000 7 Binary Holdings Ltd. 1,000,000 7,800,000 Binary Holdings Ltd. 938,978 15,000, ,300, BC Iron Limited 88,800, ,300, Endeavour Mining Corporation 50.8% * (%)

43 * Bloomberg 19 BC Iron Limited 12,780,000 9,270,000 6,130,000 71,870,000 2,570,000 1,860,000 1,230,000 14,450, ,103,930 Venturex Resources Limited 10,854,568 Bannerman Resources Limited 12,700,000 Tigers Realm Coal Limited 2,390,000 1,900,000 22,500,000 BC Iron Limited 40

44 100, ,000 49,100, ,500,000 10,000,000 77,880,000 James Mellon Plethora Jamie Gibson Plethora IV-2 IV-4 8 PLETHORA Plethora Plethora Plethora PSD502 TM Plethora 493, ,000 5,780,000 2,800,000 4,200,000 32,800,000 Plethora 560, ,000 6,190,000 PSD502 TM Plethora 1,000,000 11,050,000 Plethora 500,000 5,520, ,000 4,200, ,000 5,520,000 Plethora Plethora Plethora Plethora 41

45 Plethora Recordati PSD502 TM Recordati Plethora 5,000,000 5,420,000 42,180,000 Recordati Plethora 6,000,000 6,500,000 50,610,000 10,000,000 10,830,000 84,350,000 PSD502 TM 2,000,000 2,170,000 16,870,000 25,000,000 27,080, ,880, ,000,000 5,420,000 42,180,000 Recordati PSD502 TM 100,000, ,310, ,540,000 Recordati PSD502 TM 450,000, ,400,000 3,795,930,000 Plethora 25,000,000 27,080, ,880,000 Recordati Recordati Recordati (i) (ii) Recordati Plethora PSD502 TM Catalent Plethora Recordati 42

46 Plethora Recordati 10,000,000 10,830,000 84,350,000 PSD502 TM 2,000,000 2,170,000 16,870,000 Recordati Plethora PSD502 TM Plethora Plethora Plethora PRO PEPEBEQ PRO PDUFA (Prescription Drug User Fee Act (PDUFA date)) 10 Plethora Plethora 500,000,000 3,000,000,000 Plethora PSD502 TM PSD502 TM Plethora Plethora Plethora Plethora PSD502 TM Plethora James MellonJamie Gibson Michael G WyllieGreg Bailey Anthony Baillieu Plethora

47 Plethora Plethora Plethora (Mark Searle) (Jayne Sutcliffe) 2. (i) James Mellon James Mellon Philippa Mellon James Mellon (ii) Galloway LimitedJames Mellon (iii) Port Erin Biopharma Investments LimitedJames Mellon 29% (iv) Anderson Whamond 3. (i) Stephen Dattels(ii) David Comba (iii) Julie Oates 44

48 4. Anthony Baillieu Plethora 50.99% AstroEast.com Limited AstroEast.com (Hong Kong) Limited) 5. Greg Bailey Plethora 6. Plethora Michael G Wyllie 7. Plethora Plethora Plethora Plethora Plethora 1. Plethora (Mark Searle) (Jayne Sutcliffe) 45

49 2. (i) James Mellon James Mellon Philippa Mellon James Mellon (ii) Galloway LimitedJames Mellon (iii) Port Erin Biopharma Investments LimitedJames Mellon 29% (iv) Anderson Whamond 3. (i) Stephen Dattels(ii) David Comba (iii) Julie Oates 4. Anthony Baillieu Plethora 50.99% AstroEast.com Limited AstroEast.com (Hong Kong) Limited) 5. Greg Bailey Plethora 6. Plethora Michael G Wyllie 7. Plethora Plethora Plethora Plethora Plethora 10 Plethora 11 Jamie Gibson Plethora Jamie Gibson Plethora 46

50 Plethora Jamie Gibson Plethora Plethora Plethora 36,000 54, ,176 50,000 75, ,356 Plethora James Mellon Anthony Baillieu Jamie Gibson 200, ,600 2,345,422 Plethora Plethora Plethora Jamie Gibson 276, ,340 3,242,511 (i) 164, ,132 1,923, , ,600 2,345,422 36,000 54, ,176 (ii) 112, ,208 1,319, , ,600 2,345,422 9/12 37,503 56, ,802 Plethora Plethora Jamie Gibson Jamie Gibson (i) Jamie Gibson Plethora (ii) Plethora 12 Plethora 8.1(a) 47

51 13 David Comba Julie Oates 14 20% 130,000,000 13,000,000, ,500, ,500, Plethora (i)james Mellon 15.35%(ii)Jamie Gibson 4.08% (iii) Mark Searle 0.14% Plethora Plethora James Mellon Jamie Gibson Plethora A A Anthony Baillieu Plethora 48

52 AstroEast.com Limited AstroEast.com (Hong Kong) Limited) Baillieu % Plethora (a) James Mellon 155,358,771 Plethora 72,118,431 Plethora 4,359,531 Plethora (i) Plethora ,000,000 Plethora 400,000 (ii) Plethora 5 5,000,000 Plethora 250,000 (iii) Plethora 2 30,000,000 Plethora 632,000 (iv) Plethora 2 4,667,808 Plethora Plethora 93,356 (v) Plethora 2 845,000 Plethora 16,900 (vi) Plethora ,991 Plethora 9,025 (vii) Plethora ,725 Plethora 6,085 (viii) Plethora 2 98,384,247 Plethora Plethora 1,967,685 (ix) 340,000 5% Plethora 2 17,000,000 Plethora 49

53 (x) Plethora 1,000,000 Plethora (xi) Plethora ,118,431 Plethora 676,480 (b) Jamie Gibson Plethora 35,000,000 Plethora (c) Mark Searle 1,700,000 Plethora 57,651 Plethora 3.39 (i) 37, ,000 Plethora (ii) 20, ,000,000 Plethora Plethora

54 Plethora James MellonJamie GibsonMark Searle Anthony Baillieu Plethora Plethora Plethora Plethora Plethora Plethora 18 Jamie Gibson Mark SearleAnthony Baillieu Greg Bailey 51

55 Plethora EGM-1 EGM (4) 19 James MellonJamie GibsonMark Searle Jayne Sutcliffe 52

56 20 James Mellon Peel Hunt LLP Charles Batten Oliver Jackson Finsbury Asia Limited Faeth Birch Alastair Hetherington Plethora Michael G Wyllie Herax Partners LLPPlethora John Mellett Angus MacPherson finncap (Plethora ) Geoff Nash Grant Bergman Citigate Dewe RogersonPlethora David Dible Sylvie Berrebi 53

57 Peel Hunt LLP (Financial Conduct Authority) Peel Hunt LLP Peel Hunt LLP Peel Hunt LLP Herax Partners LLP (Financial Conduct Authority) Herax Partners LLP Plethora Plethora Herax Partners LLP 54

58 (Financial Conduct Authority) Plethora Plethora Plethora Plethora Plethora 90% 50% Plethora 14(e) 14E Plethora (Regulatory Information Service) 55

59 3(a)(10) Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora (i) (ii) (iii) 56

60 Plethora Plethora (i) (ii) Plethora (iii) Plethora 57

61 Plethora (i) (ii) Plethora Plethora Plethora Plethora 8.3(a) 1% (i) (ii) 8.3(a) (b) 1% (i) (ii) 8 8.3(b) 58

62 ( (Market Surveillance Unit) +44 (0) Plethora Plethora (c)

63 REGENT PACIFIC GROUP LIMITED 0575 PLETHORA SOLUTIONS HOLDINGS PLC 26 (i) (ii) (iii) (iv) 60

64 62 92 David Comba Julie Oates 61

65 21 PLETHORA SOLUTIONS HOLDINGS PLC 26 Plethora Plethora 26 Plethora 62

66 Plethora Plethora Plethora 11,568,619,063 Plethora 65.98% Plethora Plethora PSD502 TM PE 12 Plethora 100% (i) James Mellon 15.35%(ii) Jamie Gibson 4.08% (iii) Mark Searle 0.14% Plethora Plethora James Mellon Jamie Gibson Plethora Anthony Baillieu Plethora AstroEast.com Limited AstroEast.com (Hong Kong) Limited) Baillieu % A Plethora James MellonJamie GibsonMark Searle Anthony Baillieu 63

67 David Comba Julie Oates (i) (ii) (iii) (iv) (i) (ii) (iii) (iv) 64

68 ,000,000 Binary Holdings Ltd.BinaryRegent Markets Holdings Ltd.938,978 15,000, BC Iron Limited 88,800, Endeavour Mining Corporation 50.8% Plethora Plethora Binary

69 (i) (ii) (iii) Plethora BC Iron LimitedVenturex Resources LimitedBinaryWest China Coking & Gas Company Limited The Diabetic Boot Company 1.3 2, (31,640) (17,755) (3,726) (5,940) (25,636) (8,563) 12,

70 11,667 32,444 30,007 50,972 19,871 22,409 (3,742) (3,604) (3,225) 58,897 48,711 49, ,000 2,700, % 43.9% 17,800,000 31,600,000 10,900, % 4,200,000 18,800, % 11,200,000 8,600,000 25,600,000 (i) 11,700,000 (ii) 10,600,000 (iii) Plethora 6,000,000 Plethora 25,800,000 Plethora 32,400,000 11,700,000 Plethora 19,900,000 51,000,000 67

71 61.0% 3,700,000 3,600, % 48,700,000 58,900, , , % 100,000 12,700,000 (i) Binary 8,900,000 (ii) 1,500,000 (iii) Plethora 3,600, % 30,000,000 32,400,000 Binary 22,400,000 19,900, % Binary 3,200,000 3,600, % 49,200,000 48,700,000 ( 2. Plethora 2.1 Plethora Plethora Plethora 68

72 Plethora PSD502 TM PE Plethora PSD502 TM Plethora Recordati PSD502 TM Plethora Plethora PSD502 TM Recordati Plethora PSD502 TM PSD502 TM 2.2 Plethora Plethora Plethora Plethora Plethora Plethora 3,862 3,862 (1,519) (2,898) (16,206) (14,698) (4,108) Plethora (3,872) (8,500) (15,691) (14,574) (1,104) 69

73 ,613 5,607 1,988 (5,979) (10,425) (8,540) (2,167) (5,747) (6,812) (2,857) (114) Plethora * Plethora PSD502 TM 1,500,000 2,300,000 2,900,000 4,500,000 Plethora 3,900,000 6,000,000 8,500,000 13,100,000 Plethora 1,000 1,540 Plethora 3,600,000 5,600, , , Plethora 74.3% 10,400,000 16,100,000 6,000,000 9,200,000 Plethora 6,800,000 10,500,000 5,700,000 8,900,000 * (i) (ii) (iii)

74 * Plethora 3,900,000 5,900,000 Recordati Plethora PSD502 TM 2,900,000 4,500,000 16,200,000 25,000,000 PSD502 TM Plethora 7 Plethora 84.6% 15,700,000 24,200,000 8,500,000 13,100,000 Plethora 76, ,063 Plethora 5,600,000 8,600,000 3,600,000 5,600, % Recordati 5,000,000 Plethora 18.1% 8,500,000 13,100,000 10,400,000 16,100,000 Plethora 2,900,000 4,400,000 6,800,000 10,500,000 * Plethora 3,900,000 5,900,000 Plethora 4,100,000 6,300,000 * (i) (ii) (iii)

75 14,700,000 22,600,000 10,600,000 16,300,000 Plethora 14,600,000 22,400,000 1,100,000 1,700,000 Plethora 65, ,120 76, ,063 Plethora 2,000,000 3,100,000 5,600,000 8,600, %Plethora 8,500,000 13,100, % 2,200,000 3,300,000 Plethora 114, ,592 2,900,000 4,400,000 Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora PSD502 TM Plethora Plethora Catalent Recordati 6,000,000 Recordati Recordati 72

76 Plethora Plethora Plethora Plethora 3.(a) Plethora Plethora Plethora Plethora Plethora Plethora Plethora 1,000,000 1,480,000 11,540,000 Plethora Plethora PSD502 TM Plethora Plethora ( Plethora 3. Plethora 3.1 Plethora Plethora 2.5 4,000,000 Plethora 82,799,490 Plethora Jamie Gibson Plethora 73

77 Sharwood Limited Plethora Sharwood Limited 2,400,000 3,600,000 * Plethora 4,600,000 7,000,000 * 4,600,000 7,000,000 * Plethora 86,799,490 Plethora Plethora 10.54%1.2 3 Plethora PSD502 TM 3.2 Plethora Plethora PSD502 TM Plethora Plethora Plethora Plethora Jamie Gibson Plethora Jamie Gibson Plethora PSD502 TM Recordati * (i) (ii) (iii)

78 Jamie Gibson Plethora Plethora Michael G Wyllie PSD502 TM PSD502 TM Plethora PSD502 TM Recordati PSD502 TM PSD502 TM Plethora PSD502 TM Plethora Binary Holdings Ltd 10,000,000 Plethora Plethora Solutions Limited PSD502 TM Plethora Plethora PSD502 TM Plethora PSD502 TM PSD502 TM 75

79 Plethora PSD502 TM Plethora PSD502 TM Plethora Plethora Plethora Plethora Plethora Plethora Plethora Solutions Limited PSD502 TM PSD502 TM Plethora Plethora PSD502 TM PSD502 TM PSD502 TM Plethora PSD502 TM 76

80 Plethora Plethora Plethora Plethora Plethora Plethora Plethora 194,900, ,500,000 * Plethora * * Plethora 102,900, ,500,000 * 1,228,500,000 * Plethora 122,600, ,900,000 * 1,464,000,000 * Plethora * * (i) Plethora * * 354.5% * (i) (ii) (iii)

81 (ii) Plethora ** ** 334.8% (iii) Plethora * * 311.7% Plethora ** ** Plethora 80,800, ,600,000 ** 892,200,000 ** Plethora 97,500, ,300,000 ** 1,077,000,000 ** Plethora ** ** (i) Plethora * * 256.8% (ii) Plethora ** ** 241.3% (iii) Plethora * * 222.8% (Freiverkehr) * (i) (ii) (iii) ** (i) (ii) (iii) (iv)

82 Plethora Plethora 981,087,175 Plethora Plethora Plethora Plethora 185,420, ,600,000 (i) Plethora (ii) Plethora Plethora % (iii) Plethora Plethora 41.07% FactSet (i) (ii) Plethora (i) Plethora 12.5 Plethora (ii) (iii) (i) Plethora 12.5 Plethora (ii) (iii) 1 PSD502 TM Plethora 114, ,592 * * (i) (ii) (iii)

83 Plethora PSD502 TM PlethoraPlethora Plethora Plethora 194,900, ,500,000 * (i) Plethora (ii) (iii) Plethora Plethora * (i) (ii) (iii)

84 4.2 Plethora Plethora 194,900, ,500,000 * 45 Plethora Plethora Plethora Plethora 13.80(2)(b) 1 (d) Plethora Plethora Plethora PSD502 TM Plethora * (i) (ii) (iii)

85 Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora PSD502 TM Plethora (i) (ii) (iii) (iv) (i) Plethora PE Plethora PE 82

86 PSD502 TM (ii) Plethora Medical Marketing EconomicsMME PSD502 TM MME PSD502 TM MME (i) (ii) Plethora MME (iii) Plethora Plethora PSD502 TM Plethora Clementi Associates LtdClementi Clementi (i) (ii) Plethora (iii) Plethora Clementi Clementi Plethora Plethora PSD502 TM Plethora Plethora 83

87 PSD502 TM Clementi 85% 24 Clementi Clementi PSD502 TM (European Drug Regulatory Affairs Consulting)EUDRAC EUDRAC EUDRAC Plethora PSD502 TM 8.Plethora (i) Plethora (ii) Plethora (iii) Plethora RecordatiPlethora Plethora PSD502 TM (i) (ii) (iii) (iv) (v) Plethora Plethora EUDRAC Plethora PSD502 TM 84

88 (i) MMEClementi EUDRAC (ii) Plethora Plethora (iv) Plethora PSD502 TM Plethora Recordati PSD502 TM Plethora (i) MMEClementi EUDRAC (ii) Plethora (iii) Plethora Recordati PSD502 TM (iv) Plethora Plethora MMEClementiEUDRAC Plethora Plethora Plethora Plethora Plethora (i) (ii) (iii) (iv) (v) (vi) (vii) 85

89 10 Plethora 10 Plethora (i) (ii) (iii) Plethora Plethora Plethora (i) (ii) (iii) MMEClementi EUDRAC PSD502 TM Plethora 86

90 4.3 Plethora Plethora Plethora 11,568,619,063 Plethora 65.98% 7,600,000 Plethora Plethora 11,568,619,063 Plethora 65.98% Plethora 11,568,619,063 Plethora 14,047,113,239 (i) 823,297,686 Plethora (ii)plethora Plethora Plethora (iii) Plethora (iv) Plethora 87

91 Plethora (%) (%) James Mellon 535,107, ,108,228, Jayne Sutcliffe 45,125, ,125, Anderson Whamond 14,000, ,000, Stephen Dattels 284,266, ,266, Jamie Gibson 142,319, ,085, David Comba Julie Oates 2,500, ,500, Mark Searle 5,000, ,702, Anthony Baillieu *** 200, , Greg Bailey *** ,434, ,457,212, ,457,212, Plethora 0 0 9,873,088, ,485,730, ,532,843, *** Anthony Baillieu Greg Bailey Plethora % % % % James Mellon % % Jamie Gibson % % Stephen DattlesDavid Comba Julie Oates % % Mark Searle Jayne Sutcliffe % % 88

92 Plethora 194,900,000 Plethora 10.54% Plethora Plethora Plethora James Mellon % % Plethora Plethora PSD502 TM James Mellon Plethora Plethora % Plethora Plethora Anthony Baillieu Greg Bailey % % 25% Plethora 5.2 Plethora 89

93 5.3 (i) (ii) (a) 52,400, ,100, ,000,000 (b) 3,200,000 4,200,000 (c) 49,200, ,800, % 7,600,000 8,900,

94 5.3.4 (a) 200,000 6,500,000 (b) 8,600,000 68,600,000 8,600,000 68,600,000 Plethora 19,400,000 25,800,000 Plethora 8,300,000 2,900,000 68,600,000 PSD502 TM Plethora Plethora PSD502 TM PSD502 TM PSD502 TM 91

95 (i) (ii) (iii) Altus Investments Limited

96 Plethora PSD502 TM 26 Plethora Plethora 93

97 Plethora Plethora Plethora Plethora Plethora Plethora Plethora Plethora 4 Plethora 94

98 4 Plethora Plethora 80.12% Plethora Plethora Plethora Plethora Plethora Plethora 95

99 BC Iron Limited 12,780,000 9,270,000 6,130,000 71,870,000 2,570,000 1,860,000 1,230,000 14,450,000 96

100 Plethora PSD502 TM Plethora PSD502 TM Plethora Plethora PSD502 TM Plethora PSD502 TM PSD502 TM Pharmaserve Catalent Plethora PSD502 TM 97

101 98

102 99

103 100

104 101

105 18 102

106 103

107 104

108 CE 105

109 106

110 107

111 108

112 109

113 20 110

114 111

115 PLETHORA Plethora Plethora Plethora Plethora Plethora (i) (ii) (i) (ii) (iii) Plethora

116 Plethora Plethora 20% Plethora (C) Plethora Plethora Plethora Plethora Plethora Plethora Plethora (FSA) (PRA) 113

117 A 1 Plethora (i) Plethora Plethora Plethora Plethora 75% (ii) Plethora Plethora 2.2 (i) Plethora Plethora 75% (ii) Plethora Plethora 2.3 (i) Plethora (ii) Plethora I-1

118 3 B (a) (b) (c) 3(a) (b) 28 Plethora Plethora Plethora Plethora (d) 3(b) 3(c) I-2

119 (i) Plethora (ii) 28 Plethora Plethora (iii) Plethora Plethora Plethora Plethora Plethora (iv) Plethora (v) Plethora Plethora (vi) Plethora I-3

120 Plethora (vii) Plethora (viii) Plethora Plethora Plethora (ix) Plethora Plethora Plethora Plethora (e) Plethora Plethora Plethora (i) Plethora I-4

121 (ii) Plethora (iii) Plethora (iv) Plethora Plethora (v) Plethora (vi) Plethora Plethora (vii) Plethora (viii) Plethora (ix) Plethora I-5

122 Plethora (e)(i) (ix) (f) Plethora (i) Plethora Plethora Plethora Plethora Plethora (ii) Plethora Plethora (iii) Plethora Plethora Plethora (iv) Plethora Plethora (v) Plethora Plethora I-6

123 Plethora (vi) Plethora Plethora (vii) Plethora (viii) Plethora Plethora (ix) (i) (x) Plethora (xi) Plethora Plethora (xii) I-7

124 (xiii) (a) Plethora (b) (c) (d) Plethora (xiv) Plethora (xv) (xvi) Plethora (xvii) Plethora I-8

125 (xviii) (h) (xix) Plethora Plethora (xx) 21.1 Plethora (g) (i) Plethora Plethora (ii) Plethora Plethora Plethora Plethora (iii) Plethora Plethora (iv) Plethora Plethora I-9

126 (v) Plethora Plethora (h) (i) Plethora Plethora Plethora (ii) Plethora Plethora (iii) Plethora Plethora (A) (B) (C) Plethora (iv) Plethora I-10

127 Plethora Plethora Plethora (v) Plethora (vi) Plethora (2006) 26 (vii) Plethora (viii) Plethora (3) (b) B 1 (i) 2 Plethora Plethora Plethora I-11

128 (ii) 3(a) (h) 2 Plethora 3 9 Plethora 4 3(a) (h) 974 Plethora 90% 90% 50% Plethora Plethora 5 Plethora 6 Plethora 3(g)(ii) I-12

129 Plethora Plethora (i) (ii) 7 (a) 6(1)(c) 9(1) CMA Phase 2 Reference (b) CMA Phase 2 Reference Plethora I-13

130 I-14

131 1 1.1 Plethora 823,297,686 Plethora Plethora GB00B06GL868 Plethora Plethora 1.2 3,485,730,523 KYG7478U Plethora Plethora Plethora Plethora (A) (i) (ii) (B) 1.10 Plethora II-1

132 1.9 14,047,113, Plethora 86,799,490 Plethora 1.10 Plethora Plethora 981,087,175 Plethora (i) 823,297,686 Plethora (ii) Plethora 54,200,000 Plethora Plethora 103,589,489 Plethora (i) Plethora (ii) Plethora 1.11 Bloomberg ,530,000 2,170,000 16,900, , ,000 (1) ,000 50,000 (1) ,000 (2) , , ,000 (1) II-2

133 (2) 2.2 Plethora 580, ,000 6,410, , ,000 (1) ,000 (2) ,000 (1) (2) II-3

134 Plethora Plethora Plethora Plethora Michael G Wyllie 1,759, Michael G Wyllie 1,759,127 Plethora Plethora Plethora Plethora Plethora Plethora Plethora Forest Nominees Limited Canaccord Genuity Wealth (International) Ltd 71,804, W B Nominees Limited Walker Crips Stockbrokers Limited 13,848, Forest Nominees Limited W B Nominees Limited W B Nominees Limited W B Nominees Limited Plethora Plethora III-1

135 Forest Nominees Limited Canaccord Genuity Wealth (International) Ltd Forest Nominees Limited 71,804,175 Plethora Plethora S Glover Bay Holdings (Jersey) Limited Stonewall Holdings Limited 3,640,000 Andre de Gruchy Delphinus Pension Fund Limited 30,000 Peter Watts Fernwood Court Limited 165,000 H H E M Vernon 400,000 S D Ballard 6,500 A Simon C A. Simon 50,000 G Moustras 500,000 G P Lovett 400,000 I P Jones 800,000 I R L B Mackenzie 35,000 J G Swaisland 40,000 J Tracey 22,500 M Hockey 15,000 M J Newby 12,000,000 M C Gurney 146,000 P J L Lockwood 1,600 P A A Stone 200,000 R I A Steven 210,000 W English 30,000 W K S Lamond 22,000 C F Duncan 25,000 C Jackson 5,000 D P Lamond 62,500 L E Barr 180,000 L M S W Vidamour 15,000 L Vidamour 6,500 P J Carson N K Davidson 20,000 P Stuart 50,000 S E Le Prevost 50,000 S Carr 80,000 R L J Wasteney 40,000 R P Dean Southdown Holdings Limited 48,806,575 Spencer Bourne Spencer Holdings Limited ,000,000 Martin Henry 750,000 III-2

136 1. (a) Plethora James Mellon Plethora 340,000 13,000 5% (b) (c) BC Iron Limited BCI 12,780,000 2,570, ,103,930 Venturex Resources Limited 10,854,568 Bannerman Resources Limited 12,700,000 Tigers Realm Coal Limited 2,390,000 BCI IV-1

137 (d) 518,103,930 Venturex Resources Limited 10,854,568 Bannerman Resources Limited 12,700,000 Tigers Realm Coal Limited 2,590,000 1,890, , , , , Plethora Plethora Plethora 10.54% James Mellon 18.87% Jamie Gibson Plethora PSD502 TM Recordati Plethora Plethora PSD502 TM PSD502 TM IV-2

138 PSD502 TM Jamie Gibson Plethora Plethora Michael G Wyllie Plethora PSD502 TM PSD502 TM Plethora PSD502 TM Plethora PSD502 TM Plethora Plethora Plethora Plethora Solutions Limited Plethora Plethora PSD502 TM 10,000,000 7,050,000 77,880,000 Plethora Plethora Solutions Limited PSD502 TM Plethora Plethora Plethora 49,190, ,800,000 IV-3

139 Binary Holdings Limited Plethora Plethora 4. 9,000,000 70,200,000 8,560,000 66,770,000 IV-4

140 5. ( ( IV-5

141 Plethora Plethora Solutions Holdings plc Plethora Solutions Holdings plcplethora Plethora Plethora Plethora II 1 V-1

142 Plethora PricewaterhouseCoopers LLP V-2

143 Plethora II 3(a) 114,000 1,104, ,000 1,221,000 II 3(a) V-3

144 Plethora I. V-4 6 3,862 3,862 (611) (1,312) (2,727) (1,737) (2,064) (908) (1,586) (1,951) (1,433) (2,044) PSD502 TM 7 (15,390) (15,390) (1,519) (2,898) (20,068) (18,560) (4,108) 8 (1,519) (2,898) (16,206) (14,698) (4,108) 11 (1,308) (6,152) (933) (628) (215) , , (2,826) (8,755) (15,734) (14,617) (1,104) 12 (2,826) (8,755) (15,734) (14,617) (1,104) 21 (1,046) (3,872) (8,500) (15,691) (14,574) (1,104) 13 (1.4) (2.7) (3.2) (3.5) (0.1) (0.5) (1.9) (2.6) (3.2) (3.5) (0.1)

145 Plethora ,117 5,066 1, ,613 5,607 1, (1,566) (1,158) (1,115) (589) 22 (3,806) (6,694) (7,425) (1,234) (5,372) (7,852) (8,540) (1,823) (5,141) (4,239) (2,933) 165 (5,140) (4,239) (2,857) (607) (2,573) (344) (5,747) (6,812) (2,857) (114) 23 2,089 4,153 6,810 8, (7,836) (10,965) (9,667) (8,347) (5,747) (6,812) (2,857) (114) V-5

146 Plethora 15 79,000 79, ,509 1, ,971 1, (445) (942) (510) (310) 15 (84,701) (83,133) 22 (3,806) (6,694) (7,425) (1,234) (88,952) (90,769) (7,935) (1,544) (88,870) (87,798) (6,137) (877) (9,870) (8,798) (6,137) (877) 22 (607) (2,573) (344) (10,477) (11,371) (6,137) (1,221) 23 2,089 4,153 6,810 8, (12,566) (15,524) (12,947) (9,454) (10,477) (11,371) (6,137) (1,221) V-6

147 Plethora * * * * * 23 2,008 24,782 4, ,922 (36,056) (2,324) (3,872) (3,872) Mellon ,089 25,083 4, ,964 (39,928) (5,747) (8,500) (8,500) ,064 5,485 7,549 (312) (312) (822) 822 2,064 5, (731) 850 7,435 V-7

148 Plethora * * * * * 23 4,153 30,256 4, ,233 (47,578) (6,812) (15,691) (15,691) (73) 23 2,657 16,818 19,475 (604) (604) (115) 115 2,657 16,287 (73) ,646 6,810 46,543 4, ,893 (63,154) (2,857) V-8

149 Plethora * * * * * 23 4,153 30,256 4, ,233 (47,578) (6,812) (14,574) (14,574) 23 2,657 16,818 19,475 (604) (604) ,657 16, ,460 6,810 46,470 4, ,822 (62,152) (1,926) V-9

150 Plethora * * * * * 23 6,810 46,543 4, ,893 (63,154) (2,857) (1,104) (1,104) 23 1,423 1,423 2, (138) 2 (11) 10 1,012 1,012 1,423 1,548 (138) 1, ,847 8,233 48,091 4, ,905 (64,256) (114) * V-10

151 Plethora (2,826) (8,755) (15,734) (14,617) (1,104) 11 (1) (2) (3) (2) (15) ,233 (1,402) (707) (3,204) 7 (293) , (1,474) (2,806) (15,425) (14,109) (3,085) 200 (478) (45) (5,849) 167 (440) 253 (43) (357) (526) (1,714) (3,031) (15,513) (20,315) (3,444) 21 (42) (106) (1,756) (3,137) (15,470) (20,272) (3,444) (99) (5) (10) (1,855) (3,137) (15,475) (20,272) (3,454) V-11

152 Plethora (82) (82) 1 2 (79) (80) ,533 18,138 18,138 (312) (604) (604) CfE (31) (31) (200) 900 6,221 17,503 17,503 (954) 3,086 1,949 (2,849) (3,452) ,117 3,117 5, ,117 5, ,614 V-12

153 Plethora II. 1. Plethora 152, % 100% 100% 100% PricewaterhouseCoopers LLP Solutions PricewaterhouseCoopers LLP Limited 0.1 PricewaterhouseCoopers LLP Plethora 79,000, % 100% 100% 100% Therapeutics Limited # 1 The Urology % 100% Company Holdings 1 Limited* The Urology % Company CE Limited* 1 OTO V-13

154 Plethora * The Urology Company Limited The Urology Company Holdings Limited # Plethora Therapeutics Limited V-14

155 Plethora V-15

156 Plethora (a) 114,000 1,104, ,000 1,221,000 (i) 5% 1,000,000 Plethora Plethora PSD502 (ii) PSD502 TM PSD502 TM V-16

157 Plethora 4 (b) 5 The Urology Company Limited (c) V-17

158 Plethora (d) 5 (e) V-18

159 Plethora (f) (g) The Urology Company Limited (h) (i) V-19

160 Plethora 12 (j) (k) (l) V-20

161 Plethora (m) (n) Plethora Development Urology Co V-21

162 Plethora (o) (i) (ii) (iii) (iv) (v) (vi) (p) (i) V-22

163 Plethora (ii) (iii) (q) 10 V-23

164 Plethora (r) (s) 12 V-24

165 Plethora (t) (u) (v) (a) (i) (ii) (iii) (b) (i) (ii) (iii) (iv) V-25

166 Plethora (v) (vi) (a) (vii) (a)(i) (i) (ii) (iii) 4. (i) V-26

167 Plethora (ii) Plethora (iii) (iv) 3(a) 5. Plethora Development Urology Co The Urology Company Limited IT V-27

168 Plethora Plethora Development (3) (3) (611) (611) (1,046) (1,046) (614) (1,046) (1,660) 1 (1,308) (905) (3,872) (3,872) (300) (300) (611) (509) (1,120) (4,413) (446) (5,979) V-28

169 Plethora Plethora Development (1) (1) (1,311) (1,311) (1,312) 255 (1,057) 2 (6,152) 293 (1,586) (8,500) (8,500) 3, ,613 (216) (216) (9,267) (942) (10,425) V-29

170 Plethora Plethora Development 3,862 3,862 (6) (6) (2,727) (2,727) (5) (5) PSD502 TM (15,390) (15,390) (14,266) 43 (14,223) 1,405 (928) (1,945) (15,691) (15,691) , ,683 (605) (605) (7,425) (510) (8,540) V-30

171 Plethora Plethora Development 3,862 3,862 (1,767) (1,767) (4) (4) PSD502 TM (15,390) (15,390) (13,299) 43 (13,256) 709 (624) (1,403) (14,574) (14,574) ,697 7,046 (425) (425) (7,827) (720) (8,972) V-31

172 Plethora Plethora Development (11) (11) (2,604) (2,604) (4) (4) (2,619) (2,619) 3,206 (211) (1,480) (1,104) (1,104) , ,053 (279) (279) (1,578) (310) (2,167) V-32

173 Plethora 3,862,000 3,862, ,862 3, PSD502 TM Shionogi Paul Capital PSD502 TM PSD502 TM PSD502 TM 25,000,000 15,390, ,000 15,390, , V-33

174 Plethora (81) , , ,294 V-34

175 Plethora 9. W.J. Robinson M.G. Wyllie J.R. Openshaw J. Mellon R. Horsman M.G. Wyllie 110,000 Mens Health Limited R. Horsman 24,000 High Lees Consulting Limited V-35

176 Plethora W.J. Robinson M. Collis M.G. Wyllie J.R. Openshaw J. Mellon R. Horsman 9 9 G. Bailey J.R. Openshaw W.J. Robinson 26,000 23,000 M. Collis Maven Capital Partners (UK) LLP Maven Capital Partners (UK) LLP 6,000 M. Collis Arc Portfolio Management LimitedM. Collis Arc Portfolio Management Limited M.G. Wyllie 110,000 Mens Health LimitedM.G. Wyllie Mens Health Limited R. Horsman 9,000 High Lees Consulting Limited V-36

177 Plethora G. Bailey 12,000 Culminant Capital IncG. Bailey Culminant Capital Inc J. Gibson M. Collis M.G. Wyllie J. Mellon G. Bailey ,092 M.G. Wyllie 110,000 Mens Health Limited Global Pharma ConsultingM.G. Wyllie Mens Health Global Pharma Consulting G. Bailey 27,000 Culminant Capital IncG. Bailey Culminant Capital Inc 27,000 M. Collis Maven Capital Partners (UK) LLP Maven Capital Partners (UK) LLP 36,000 M. Collis M. Collis 2,500 33,500 Arc Portfolio Management LimitedM. Collis Arc Portfolio Management Limited 36,000 J. Gibson V-37

178 Plethora J. Gibson M. Collis M.G. Wyllie J. Mellon G. Bailey M.G. Wyllie 66,000 Mens Health Ltd Global Pharma ConsultingM.G. Wyllie Mens Health Global Pharma Consulting G. Bailey 20,000 Culminant Capital IncG. Bailey Culminant Capital Inc 20,000 M. Collis Maven Capital Partners (UK) LLP Maven Capital Partners (UK) LLP 27,000 M. Collis M. Collis 1,500 25,500 Arc Portfolio Management LimitedM. Collis Arc Portfolio Management Limited 27,000 J. Gibson V-38

179 Plethora J. Gibson M. Collis M.G. Wyllie J. Mellon G. Bailey A. Baillieu ,011 1,248 M.G. Wyllie 27,000 Global Pharma ConsultingM.G. Wyllie Global Pharma Consulting G. Bailey 20,000 Culminant Capital IncG. Bailey Culminant Capital Inc 7,000 M. Collis Maven Capital Partners (UK) LLP Maven Capital Partners (UK) LLP 21,000 M. Collis M. Collis 13,000 8,000 Arc Portfolio Management LimitedM. Collis Arc Portfolio Management Limited M. Collis 38,000 J. Gibson V-39

180 Plethora , , ,301 V-40

181 Plethora 84,082 1,000,000 3 * 3 # 2 * , ,123 1,000,001 1,500, , ,164 1,500,001 2,000, , ,205 2,000,001 2,500, , ,412 4,500,001 5,000, , ,824 9,500,001 10,000, * # 84,082 1,000, V-41

182 Plethora 10. i. 2,118, ,118, , , , (1,555,555) 77 (362,072) 138 (362,072) 138 (68,571) 175 2,118, , , , , V-42

183 Plethora 2,118, , , , ,555, , , , ,857 68, , , , ,460 2,118, , , ,460 V-43

184 Plethora M.G. Wyllie 724, , M.G. Wyllie 724,491 (444,444) 280, M.G. Wyllie 280,047 (100,000) 180, M.G. Wyllie 180,047 (68,571) 111, ii. V-44

185 Plethora (1) PCH Shionogi 11.11% (2) 30,000, % (3) Recordati 11.11% (4) 11.11% (5) PSD 502 TM 11.11% (6) 11.11% (7) PSD502 TM 33.33% Plethora V-45

186 Plethora ,000 16,000,000 1,000, % 81% 81% % 3.0% 3.0% 0% 0% 0% ,000,000 38,200, % 80% % 0.5% 0% 0% 14 6 V-46

187 Plethora 1,355, ,343,600 1,343,600 17,100,000 17,100,000 54,200,000 17,160,000 38,200,000 38,200,000 (1,355,975) (47,625) (1,100,000) (1,100,000) 1,343,600 17,100,000 54,200,000 54,200,000 54,200,000 V-47

188 Plethora 770, , , , ,343,600 1,343,600 42, ,750 30,000 (800,750) ,850 (47,625) 30,000 (555,225) , , ,000,000 16,000, ,000,000 1,000, ,343,600 (47,625) 17,160,000 (1,355,975) 17,100,000 V-48

189 Plethora 91, ,000 (100,000) ,000,000 16,000, ,000,000 (1,000,000) ,200,000 38,200, ,100,000 (1,100,000) 38,200,000 54,200,000 V-49

190 Plethora 775, ,000 (100,000) ,000,000 16,000, ,000,000 (1,000,000) ,100,000 (1,100,000) 16,000, ,000 16,000,000 16,000, ,200,000 38,200, ,200,000 54,200,000 1,012,000 V-50

191 Plethora W.J. Robinson 110, ,375 J.R. Openshaw 254, ,625 M.G. Wyllie 405, , , ,800 W.J. Robinson 110,375 (47,625) (62,750) J.R. Openshaw 254,625 (254,625) M. Collis 500, ,000 M.G. Wyllie 405,800 16,000,000 (405,800) 16,000, ,800 (47,625) 16,500,000 (723,175) 16,500, ,000 J. Gibson J. Gibson 500,000 Arc Portfolio Management Limited M. Collis M. Collis Arc Portfolio Management Limited V-51

192 Plethora M.G. Wyllie 16,000,000 PSD502 TM J.R. Openshaw 9,400,000 4,000,000 5,400,000 J. Gibson 500,000 (500,000) 35,000,000 35,000,000 J. Mellon 1,000,000 1,000,000 G. Bailey 1,000,000 1,000,000 M. Collis 500,000 (500,000) 1,000,000 1,000,000 M.G. Wyllie 16,000,000 16,000,000 17,000,000 (1,000,000) 38,000,000 54,000,000 35,000,000 J. Gibson J. Gibson 500,000 J. Gibson 1,000,000 M. Collis Arc Portfolio Management Limited M. Collis 500,000 1,000,000 G. Bailey V-52

193 Plethora 1,000,000 J. Mellon J. Gibson 500, ,000 J. Mellon G. Bailey M. Collis 500, ,000 M.G. Wyllie 16,000,000 16,000,000 17,000,000 17,000,000 J. Gibson 35,000,000 35,000,000 J. Mellon 1,000,000 1,000,000 G. Bailey 1,000,000 1,000,000 M. Collis 1,000,000 1,000,000 M.G. Wyllie 16,000,000 16,000,000 54,000,000 54,000,000 V-53

194 Plethora 11. (994) (919) (933) (628) (215) (314) (5,233) (1,308) (6,152) (933) (628) (215) , , , ,219 13,000 J. Mellon 340,000 5% 22 V-54

195 Plethora % 23.25%21.50% 20.33% (2,826) (8,755) (15,734) (14,617) (1,104) (692) (2,036) (3,382) (3,156) (221) ,014 3,215 3, V-55

196 Plethora 29,670,000 33,820,000 50,173,000 49,833,000 26% 24% 24% 23% 23% 21% 24.5%23.25% 21.5% 20.33% 1% 20% 13. (2,826) (1.4) (8,755) (2.7) (15,734) (3.2) (14,617) (3.5) (1,104) (0.1) (1,046) (0.5) (3,872) (1.9) (8,500) (2.6) (15,691) (3.2) (14,574) (3.5) (1,104) (0.1) (3,872) (1.9) (8,500) (2.6) (15,691) (3.2) (14,574) (3.5) (1,104) (0.1) 205,702, ,551, ,279, ,274, ,220,676 V-56

197 Plethora (46) (48) (46) (48) ,000 V-57

198 Plethora ,268 79,288 79,350 80, ,288 79,350 80,010 80, , , ,010 80,010 79,000 79, Plethora Therapeutics Limited The Urology Company Holdings Limited 62,000 The Urology Company Holdings Limited Plethora Therapeutics Limited 79,598,000 1 V-58

199 Plethora , , (38) V-59

200 Plethora The Urology Company Limited (38) 38 The Urology Company Limited V-60

201 Plethora ,117 5,066 1, ,509 1, ,230,000 6,880,000 10,035,000 9,810, , ,000 V-61

202 Plethora 1,220,000 2,765,000 2,965,000 2,342, , , ,566 1,158 1, V-62

203 Plethora 21. The Urology Company LimitedTheUrology CoThe Urology Co Capital for Enterprise Fund A L.P.CfE CfE 43,068 25% CfE The Urology Co (517) (41) (890) (102) (221) (58) (1,111) (160) (1,046) (110) (1,046) (110) (1,046) V-63

204 Plethora (1,046) (110) (22) (43) (42) (106) (42) (106) V-64

205 Plethora CfE CfE 2,220 1, CfE Galloway 756 1,023 Galloway 3,620 2, Galloway Mellon Mellon ,806 6,694 7,425 1,234 CfE 818 CfE 238 CfE 94 Galloway 897 Galloway 369 Galloway 100 Mellon Mellon , ,413 9,267 7,425 1,578 V-65

206 Plethora (i) 13% % , , , ,585,342 14% , ,806,575 (ii) CfE Capital For Enterprise Fund A L.P.CfE Maven Capital Partners (UK) LLP 1,000,000 CfE CfE 10% V-66

207 Plethora 20% 25% CfE 3% 500,000 CfE 128,384 6,419,190 14%CfE 25% 2 CfE 1 3% CfE CfE 67,000 85% CfE 200, ,566, ,326 The Urology Co The Urology Co CfE CfE 43,068 CfE CfE 2 200, ,652 14,632,600 CfE 569,595 V-67

208 Plethora CfE 2 569, ,384 43,901, , ,595 (iii) Galloway Galloway LimitedJ. Mellon 850,000 Galloway Galloway 10% 25%Galloway Limited 5% 1,500,000 Galloway 850,000 78, ,900,685 14%Galloway 25% Galloway 2 Galloway % Galloway Galloway 68,000 95% Galloway 2 850, ,514, , ,000 V-68

209 Plethora (iv) Mellon J. Mellon 350, ,000 Mellon 1 J. Mellon 350,000 PSD502 TM 20 10% 75% 15, ,123 10%Mellon 1 75% 2 295,000 10% 75% J. Mellon 340,000 5% , Mellon 2 J. Mellon 200,000 10% 33% 5 25,000 33% 2 V-69

210 Plethora 34,000 10% 33% 2 J. Mellon 2 210, ,870, , ,000 MavenJ. Mellon Galloway CfE 1, Galloway Mellon CfE 800 Galloway 850 Mellon ,200 3,000 1, V-70

211 Plethora ,941, ,274, ,011, ,297,686) 1 2,089 4,153 6,810 8, ,000, ,000 32,000 1,184, ,200,000 2,124, ,672, ,585, ,707 6,419,190 2 CfE 128,384 3,900,685 2 Galloway 850,000 78,014 V-71

212 Plethora 767,123 2 Mellon 1350,000 15, ,205, , ,000,000 4,400,000 6,279, ,355,975 J. Mellon M. Collis 923,432 4,000,000 J.R. Openshaw Capital for Enterprise Fund A L.P. Maven Capital Partner (UK) LLP 1,000, ,000 21,326 25% 50,000 13,566, ,326 CfE 2 200,000 25% 292,652 14,632, ,998, ,499,236 15,929,000 V-72

213 Plethora 9 25,299, ,649,745 2,277,000 Forest Nominees Limited 800, ,132 48,806, ,132 CfEJ. Mellon Galloway Limited Maven Capital Partners (UK) LLP 2 569, , , ,285,957 1,216,124 1,629, ,297, ,083 30,256 46,543 48,091 4,908 4,908 4,908 4, ,964 1,233 1,893 2,905 (39,928) (47,578) (63,154) (64,256) (7,836) (10,965) (9,667) (8,347) V-73

214 Plethora 3(j) 3(q) V-74

215 Plethora 24, (33,387) (8,187) (4,747) (4,747) Mellon , (38,134) (12,566) (8,321) (8,321) ,485 5,485 (312) (312) (125) , (46,312) (15,524) (14,412) (14,412) 73 (73) 16,818 16,818 (604) (604) , ,091 (60,724) (12,947) 1,069 1, (138) 2 (11) 1,423 1,423 1,012 1,012 48, ,103 (59,653) (9,454) V-75

216 Plethora V-76

217 Plethora 28. (a) Arc Portfolio Management Limited Culminant Capital Inc Galloway Limited Global Pharma Consulting High Lees Consulting Limited J. Mellon Lucia Capital LLP Maven Capital Partners (UK) LLP Mens Health Limited Arc Portfolio Management Limited 8 8 Culminant Capital Inc Galloway Limited Global Pharma Consulting High Lees Consulting Limited 9 9 J. Mellon Lucia Capital LLP 5 5 Maven Capital Partners (UK) LLP Mens Health Limited V-77

218 Plethora Arc Portfolio Management Limited Culminant Capital Inc Galloway Limited Global Pharma Consulting High Lees Consulting Limited J. Mellon Lucia Capital LLP Maven Capital Partners (UK) LLP Mens Health Limited Arc Portfolio Management Limited Culminant Capital Inc 6 6 Galloway Limited Global Pharma Consulting High Lees Consulting Limited J. Mellon Lucia Capital LLP Maven Capital Partners (UK) LLP Mens Health Limited V-78

219 Plethora Arc Portfolio Management Limited Culminant Capital Inc Galloway Limited Global Pharma Consulting High Lees Consulting Limited J. Mellon Lucia Capital LLP Maven Capital Partners (UK) LLP Mens Health Limited Arc Portfolio Management Limited 4 3 Culminant Capital Inc Galloway Limited 847 1,031 1,242 Global Pharma Consulting 19 High Lees Consulting Limited 12 J. Mellon Lucia Capital LLP Maven Capital Partners (UK) LLP 1, Mens Health Limited M. Collis Arc Portfolio Management Limited 8,000 36,000 28,000 12,000 M. Collis Arc Portfolio Management Limited V-79

Plethora Plethora PSD502 PSD502 PSD502 Recordati Plethora PSD502 2

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