股份代號 : 867 中期報告 2015 CHINA MEDICAL SYSTEM HOLDINGS LIMITED 康哲藥業控股有限公司 康 哲 藥 業 控 股 有 限 公 司 CHINA MEDICAL SYSTEM HOLDINGS LIMITED (Stock Code:867) Interim Report 2015 2015 INTERIM REPORT 中期報告

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Maples Corporate Services Limited PO Box 309 Ugland House Grand Cayman, KY1-1104 Cayman Islands 11 A 68 518057 510 21 2106 183 17 1712 1716 867 www.cms.net.cn 2015 1

22.7%1,676.41,366.7 20.5%493.9410.0 18.4%0.2024 0.1709 411.2 154.1 0.079416.9%0.0679 2,000 1,500 1,000 630.5 1,040.7 833.5 1,366.7 1,676.4 600 400 195.8 314.5 260.6 410.0 493.9 500 200 0 2011 2012 2013 2014 2015 0 2011 2012 2013 2014 2015 2 2015

1,676.41,366.7 22.7% 493.9410.020.5% 1. 2015 3

1.1 26.61% 1.2 1.3 (CMS024) Traumakine 4 2015

100% Faron FaronFaron FaronFaron 15.72% Traumakine CMS Faron CMS Traumakine CMS Traumakine 2. 2.1 H.Lundbeck A/S IMS 451.1 17.3% Dr. Falk Pharma GmbH IMS 318.8 19.5% 2015 5

rhbnp 26.61% 218.9 28.1% GMPGMP GMP Dr. Falk Pharma GmbH 0.5 110.5 86.6 24.7% Biocodex 78.1 44.0% 6 2015

Pharma Stulln GmbH (CFDA) 70.1 15.7% 46.2 26.61% (EDL) 22.7 Mobilat Produktions GmbH 11.9 2015 7

Nordmark Arzneimittel GmbH & Co.KG 4.6 Novartis AG Novartis Pharma AG Novartis Farma S.P.A. (HPRL) HPRL 8 2015

Norgine B.V. 3350 29.8 15.4% 2.2 160.4 21.5% GMP 80.7 17.1% CFDA 100% 68.7 330.0% 2015 9

1.9 7.5% (%) 13.1 4.8 4.2 4.1 2.8 1.8 1.4 0.7 0.3 0.1 0 0 0 26.9 2.3 19.0 9.6 5.2 4.7 25.7 1.5% 10 2015

3. 3.1 CFDA CFDA CFDA Budenofalk Dr. Falk Pharma GmbH JXHL1100207 JXHL1100106 Maltofer Vifor Pharma JXHL1400152 JXHL1400153 Uro-Vaxom Stimol Biocodex JXHL1300177 Ze 339 Max Zeller JXZL1500004 Ze 440 Söhne AG JXZL1500003 Ze 450 JXZL1500002 Beacon Pharmaceuticals Limited CFDA(http://www.sfda.gov.cn) 2015 11

3.2 3.2.1 (CMS024) (CMS024) 3521 13% 3.2.2 Traumakine A&BA&B Traumakine A&BTraumakine A&B Traumakine 1a(ARDS) ARDS ARDS Traumakine 12 2015

Traumakine I/II 28 8%32% 28 81% P=0.01)I/II(EMA)(CHMP) (SAWP) SAWP CHMP Traumakine 12 ARDS ARDS ARDS 59/1050%35% 45%) 1. 18,000 2015 13

2. 6,000 GMP GMP 14 2015

22.7% 1,676.41,366.7 224.7% 30.0% 957.9736.9 57.1% 55.9%53.9% 41.1% 352.4249.7 21.0% 18.7%18.3% 30.9% 93.071.0 5.5%5.2% 0.3 2015 15

5.4%30.031.8 5,223.4%5.00.1 9 219.1%14.74.6 20.5% 493.9410.0 121.3%419.3189.5 78 57 21 38.4%805.9 582.5 55 76 59.7%126.5 79.2 1726 411.2 154.1 243.5150.8 16 2015

2015 2 42015 8 175 0.0794 0.0963 18317 1712-1716 XV 352 2015 17

1 1,142,719,000(L) 2 45.94% 2,406,500(L) 3 0.10% 10,382,162(L) 4 0.42% 20,038,225(L) 0.81% 75,000,000(L) 5 3.02% 10,382,162(L) 6 0.42% 6,668,250(L) 0.27% 10,382,162(L) 6 0.42% 6,074,237(L) 0.24% 750,000(L) 7 0.03% 10,382,162(L) 6 0.42% 1. L 2. Treasure Sea Limited 3. Treasure Sea Limited 4. Fully Profit Management (PTC) Limited Fully Profit Management (PTC) Limited 6 5. Viewell Limited 6. Fully Profit Management (PTC) Limited 10,382,162 10,382,162 7. 18 2015

XV23 336 2015 3 31Treasure Sea Limited 0.005145,000,000 11.86 72,500,000 2015 3 31 12.9 362,5002014 4 30 857.0111.82 2015 3 31 2,418 2015 19

1318) 8193) 13.51B(1) A.2.1 20 2015

(www.hkex.com.hk) (www.cms.net.cn) 2015 21

3 1,676,404 1,366,738 (718,473) (629,846) 957,931 736,892 30,049 31,763 (352,368) (249,747) (93,016) (71,048) (14,681) (4,601) 5,004 94 532,919 443,353 4 (39,028) (33,396) 5 493,891 409,957 486 2,881 62,070 (14,266) 64 2 494,441 460,644 495,049 412,664 (1,158) (2,707) 493,891 409,957 495,599 463,351 (1,158) (2,707) 494,441 460,644 7 0.2024 0.1709 0.2024 0.1709 22 2015

8 285,557 253,876 54,287 51,080 9 1,310,559 1,308,462 1,012,225 440,896 1,372,169 1,184,591 138,227 90,179 10,305 11,183 21,932 19,418 4,205,261 3,359,685 419,276 189,456 10 1,209,629 876,245 4,150 40,861 26,899 23,991 209,481 411,200 243,515 2,109,107 1,545,596 11 557,414 252,643 12 514,586 484,241 12,361 5,500 27,746 46,287 1,112,107 788,671 997,000 756,925 5,202,261 4,116,610 2015 23

13 85,200 82,974 4,907,958 3,907,865 4,993,158 3,990,839 64,472 5,057,630 3,990,839 110,066 81,177 34,565 44,594 144,631 125,771 5,202,261 4,116,610 22 37 24 2015

82,974 1,767,684 19,545 29,186 110,935 (11,016) 1,137,164 127,055 3,263,527 13,060 3,276,587 1,045,702 1,045,702 (2,707) 1,042,995 1,793 1,793 1,793 241,133 241,133 241,133 (55,264) (55,264) (55,264) (215,055) (215,055) (215,055) 19 19 19 (29,186) 1,812 1,045,702 1,018,328 (2,707) 1,015,621 (163,961) (127,055) (291,016) (291,016) (167,101) 167,101 26,909 (26,909) (10,353) (10,353) 82,974 1,767,684 19,545 137,844 (9,204) 1,824,895 167,101 3,990,839 3,990,839 495,049 495,049 (1,158) 493,891 550 550 550 550 495,049 495,599 (1,158) 494,441 15 65,630 65,630 13 2,226 676,612 678,838 678,838 6 (5,017) (167,101) (172,118) (172,118) 6 (197,487) 197,487 4,548 (4,548) 85,200 2,444,296 19,545 142,392 (8,654) 2,112,892 197,487 4,993,158 64,472 5,057,630 2015 25

82,974 1,767,684 19,545 29,186 110,935 (11,016) 1,137,164 127,055 3,263,527 13,060 3,276,587 412,664 412,664 (2,707) 409,957 47,804 2,883 50,687 50,687 47,804 2,883 412,664 463,351 (2,707) 460,644 (10,353) (10,353) (127,055) (127,055) (127,055) (163,961) 163,961 1,563 (1,563) 82,974 1,767,684 19,545 76,990 112,498 (8,133) 1,384,304 163,961 3,599,823 3,599,823 26 2015

52,603 455,002 (22,513) (51,847) (300,100) (30,000) (88,737) 15 (240,833) (156,759) 185,490 299,751 5,924 14,495 2,971 1,023 11,414 (369,061) (660) (9,730) (6,610) (172,118) (127,055) (3,009) (2,157) 449,612 290,327 (459,267) (311,923) 678,838 484,326 (157,418) 167,868 296,924 243,515 487,943 (183) (3,124) 411,200 781,743 2015 27

1. 2. 3. 28 2015

4. 40,200 33,172 1,776 1,317 19 21 41,995 34,510 (2,967) (1,114) 39,028 33,396 5. 7,708 7,470 26,691 12,375 688,066 613,769 (5,924) (14,495) (4,178) 4,827 2015 29

6. 0.0692 0.0526 172,118,000 127,055,000 0.0794 0.0679 7. 495,049 412,664 2,445,990,606 2,414,747,512 8. 884,0001,074,000 21,629,000 50,773,000 30 2015

9. 1,304,356 1,304,356 11,536 11,536 (5,333) (7,430) 1,310,559 1,308,462 2,329,279 1,451,344 13 24.49% 26.61% 2015 31

10. 810,172 584,770 (4,259) (2,270) 805,913 582,500 154,080 150,751 34,830 35,225 214,806 107,769 1,209,629 876,245 0 90 0-90 732,020 544,774 91-365 73,255 37,354 365 638 372 805,913 582,500 32 2015

11. 0-90 126,299 79,158 91-365 52 3 365 182 61 126,533 79,222 47,022 56,317 42,955 19,653 232,163 108,741 97,451 557,414 252,643 0 120 12. 449,612,000 290,327,0003.25% 3.80% 2015 33

13. 20,000,000 765,218 2,414,747 82,974 72,500 2,226 2,487,247 85,200 11.86 Treasure Sea Limited 0.005 72,500,000 14. 1 3 1 2 1 3 34 2015

15. 52.01% 258,705 16,835 11,657 114,489 1,199 11,812 28,703 580 569 46,741 2,977 2,872 (40,000) (31,136) (30,541) 136,757 258,705 65,630 (136,757) 187,578 2015 35

15. 243,705 (2,872) 240,833 15,000 255,833 681,000 28,000 1,697 496 36 2015

16. 56,496 122,353 243,204 56,496 365,557 17. (a) 421 529 95,623 148,650 (b) 1,681,000 1,899,000 2015 37