ormones /
11 ormones Prostaglandins Peptide ormones Steroid ormones
Steroid ormones /
Steroid ormones
1 2 A 3 4 11 10 B 5 6 9 12 C 8 7 13 17 D 16 14 15
: stomach pineal hypothalmus pituitary parathyroid thyroid thymus adrenal kidney duodenum pancreas ovary uterus testes
2 3 12 11 1 10 9 5 4 6 8 7 18 17 16 13 14 15 2 3 1 4 19 10 12 11 9 8 7 5 6 18 17 13 16 14 15 2 3 1 4 19 10 5 12 21 18 20 11 17 13 16 9 8 14 15 7 6
-
- 1903-1940 1932 1932 1935 Corticosterone1939 D
- 1940
Estradiol Testosterone Prop. Mifepristone
1 2
Estradiol -1,3,5(10)- -3,17
1. Estradiol A C-3 C-17 0.855nm C-10
2. Estradiol 1927 1935
3. Estradiol 10-8 10-10 mol /L
4. Estradiol 1 FeCl 3 2 3 Kober 2 S 4 Fe 3 + N 3 2
5. Estradiol
6. Estradiol Estradiol 17
7. Conjugated Estrogens Estradiol
8. Estradiol Estradiol
N.
Diethlstilbestrol (E)-1,2- (4- )-1,2-
Schueler(1946) 0.855nm 0.388nm 0.855nm 0.855nm 0.388nm 0.388nm
Tamoxifen Citrate N. (Z)-N,N- -2-[4-(1,2- -1- ) ]
N.
1. Testosterone 17 β- -4- -3-
2. Testosterone Propionate 17 β- -4- -3-
1.. 5 17 4 4-150 100 10
2. Testosterone 1 Testosterone 2 Testosterone 17 Methyltestosterone
1 Progesterone 2 3 1 2
1. Progesterone C 3 17-4- -3 20-
1. Progesterone C 3 17 -
1. Progesterone
2. Medroxy progesterone 17-4- -3 20-
2. 17-6 - 6 16 3 20
2.
3. 17a 19 18
3. Norethisterone 17
3. Levonorgestrel 17
3. Levo norgestrel L FS
Steroid ormones