ormones /
Steroid ormones
2 3 12 11 1 10 9 5 4 6 8 7 18 17 16 13 14 15 2 3 1 4 19 10 12 11 9 8 7 5 6 18 17 13 16 14 15 2 3 1 4 19 10 5 12 21 18 20 11 17 13 16 9 8 14 15 7 6
Estradiol Testosterone Prop. Mifepristone
1956 Pincus 19-
Norethisterone 17
Levonorgestrel 18-19- 17-17
17a 19 18
L FS
Mifepristone N 1 19- (2) 4 9 - (3) 11-4 17-11
N 5
N Norethisterone Norethisterone 1 C-11β ; 2 C 17 ; 9 C- 11 β- Norethisterone Mifepristone 9 Mifepristone 34h
1927 Rogoff Cortisone Cortisol Corticosterone 11 17 - -11-
1 2 3 2 1 10 11 9 12 8 17 16 13 14 15 3 4 5 6 7 hydrocortisone
1.
1 2
2 C C C 2 Aldosterone Desoxycorticosterone
Corticosterone Cortisol (hydrocortisone) Cortisone
ydrocortisone 1 2 C 11 -β-, C 17 -, C 21-11
ydrocortisone xidation Cortisone Reduction xidation/reduction C 3-keto- 4 and 20-keto reduced Acid metabolites
2 1 10 11 9 12 8 17 16 13 14 15 3 4 5 6 7
3 C-9 α-f 4. C-16 F
Dexamethasone Acetate F 1 2 C 1-2 3 C 9 - F,C 16 -C 3, 4 16
Dexamethasone Acetato Dexamethasone 4h 15 50 50 A 1 β-
F 1 C 9 C 9 C-9F 2 C 16 C 9 C 16 ydrocortisone 20 30 C-16 C16- - C16-β- 3 C 6 C-6 C 6 Fluocinonid Acetate
F Dexamethasone Acetate 1 A 4-3- 2 B C 3 D C-17
ormones