Sihuan Pharmaceutical Holdings Group Ltd. 0460 4,732,700 3,042,531 55.6% 3,699,714 2,289,415 61.6% 1,462,082 1,047,755 39.5% 1,303,012 904,402 44.1% 78.2% 75.2% 27.5% 29.7% 25.18 17.48 56 58 34 36 2.1 5.8 3,042.5 55.6% 4,732.7 44.1% 1,303.0 44.1% 25.18 2.1 1 0.01 1 1
1,441,677 924,052 34,437 30,894 4 2,880,622 3,735,030 337,998 165,637 5 154,192 34,069 40,962 119,939 265,176 122,521 4,848,742 5,438,464 101,283 91,472 5 1,398,041 769,120 6 776,074 717,921 233,651 898,560 1,508,076 1,543,907 4,017,125 4,020,980 1,145,781 5,162,906 4,020,980 10,011,648 9,459,444 2
7 44,419 44,419 7 5,573,951 5,573,951 89,329 65,256 16 108,824 300,151 2,065,782 1,100,551 7,882,305 7,084,328 115,485 102,927 7,997,790 7,187,255 140,862 208,532 9 63,227 207,407 8 5,880 5,880 209,969 421,819 10 1,253,107 867,368 8 180,800 767,234 129,770 215,768 1,563,677 1,850,370 240,212 1,803,889 1,850,370 2,013,858 2,272,189 10,011,648 9,459,444 3,359,017 2,170,610 8,207,759 7,609,074 3
11 4,732,700 3,042,531 12 (1,032,986) (753,116) 3,699,714 2,289,415 11 19,720 5,825 11 399,006 271,406 12 (2,329,531) (1,312,251) 12 (326,827) (206,640) 1,462,082 1,047,755 13 120,887 131,456 13 (8,625) (7,323) 112,262 124,133 (6,830) (6,347) (63) 1,567,451 1,165,541 14 (257,368) (243,999) 1,310,083 921,542 1,303,012 904,402 7,071 17,140 1,310,083 921,542 4
15 25.18 17.48 1,310,083 921,542 6 (1,021) (1,635) 6 2,074 1,021 1,311,136 920,928 1,304,065 903,788 7,071 17,140 1,311,136 920,928 108,824 460,577 5
44,419 5,573,951 153,485 1,173,679 6,945,534 48,409 6,993,943 904,402 904,402 17,140 921,542 (1,635) (1,635) (1,635) 1,021 1,021 1,021 (614) (614) (614) (614) 904,402 903,788 17,140 920,928 7,678 7,678 7,678 (662,404) (662,404) (662,404) 15,475 (15,475) 23,153 (667,879) (654,726) (654,726) 4,310 4,310 (110,268) (110,268) 33,068 (77,200) (500) 500 (87,615) (677,379) (764,994) 37,378 (727,616) 44,419 5,573,951 65,256 1,400,702 7,084,328 102,927 7,187,255 6
44,419 5,573,951 65,256 1,400,702 7,084,328 102,927 7,187,255 1,303,012 1,303,012 7,071 1,310,083 (1,021) (1,021) (1,021) 2,074 2,074 2,074 1,053 1,053 1,053 1,053 1,303,012 1,304,065 7,071 1,311,136 16,589 16,589 16,589 (522,677) (522,677) (522,677) 6,431 (6,431) 23,020 (529,108) (506,088) (506,088) 5,487 5,487 23,020 (529,108) (506,088) 5,487 (500,601) 44,419 5,573,951 89,329 2,174,606 7,882,305 115,485 7,997,790 7
1,800,618 1,283,628 (289,985) (237,564) 1,510,633 1,046,064 (20,000) (1,180,000) (47,309) (77,200) 1,488 4,098 1,415 22,787 664,909 (898,560) (774,000) (716,900) 36,393 (846,125) (529,229) (234,498) (185,420) (87,955) (80,655) (24,853) 716,900 788,919 (7,351) 87,349 123,838 (497,868) (2,764,091) (704,148) 180,800 767,234 5,487 4,310 (522,677) (662,404) (8,058) (360) (1,048,596) 108,780 (35,831) (1,609,247) 1,543,907 3,153,154 1,508,076 1,543,907 8
1. Plenty Gold Enterprises LimitedPlenty Gold Clarendon House, 2 Church Street, P.O. Box HM 1022, Hamilton HM DX, Bermuda 2000 21 10025 2. (i) 9
1 10 28 11 12 13 13 (ii) 32 10 12 27 36 39 10
21 19 9 3. 10% 11
4. (a) 2,645,905 54,941 425,815 178,804 22,173 3,327,638 (27,370) (108,887) (3,955) (140,212) (37,060) (1,063) (69,156) (107,279) 2,608,845 27,571 315,865 109,648 18,218 3,080,147 2,608,845 27,571 315,865 109,648 18,218 3,080,147 351,990 18,212 218 370,420 100 (100) (5,745) (37) (5,782) 98,590 98,590 291,857 291,857 (12,502) (12,502) (46,095) (38,575) (3,030) (87,700) 2,707,435 333,466 569,247 109,513 15,369 3,735,030 2,744,495 406,931 727,837 191,171 22,354 4,092,788 (73,465) (157,527) (6,985) (237,977) (37,060) (1,063) (81,658) (119,781) 2,707,435 333,466 569,247 109,513 15,369 3,735,030 2,707,435 333,466 569,247 109,513 15,369 3,735,030 27,001 22,314 183 49,498 2,700 (2,700) (1,307) (3) (1,310) (480,499) (271,729) (8) (752,236) (6,979) (6,979) (88,693) (51,638) (3,050) (143,381) 2,226,936 271,774 248,580 120,841 12,491 2,880,622 2,263,996 433,932 428,616 209,478 22,521 3,358,543 (162,158) (178,973) (10,030) (351,161) (37,060) (1,063) (88,637) (126,760) 2,226,936 271,774 248,580 120,841 12,491 2,880,622 (a) 12
5. 867,716 599,582 165,572 154,192 103,554 20,409 96,544 69,426 91,944 72,711 79,703 1,398,041 923,312 154,192 1,398,041 769,120 3 632,298 563,994 3 6 105,537 32,607 6 1 129,420 2,666 1 461 315 867,716 599,582 13
6. 717,921 780,135 774,000 716,900 (717,921) (780,135) 2,074 1,021 776,074 717,921 776,074 717,921 4.94%3.69% 14
7. 0.01 10,000,000 5,175,024 44,419 5,573,951 5,618,370 0.01 10,000,000 5,175,024 44,419 5,573,951 5,618,370 8. (a) 5,880 5,880 (b) 180,800 704,148 63,086 186,680 773,114 (a) 6.40% 6.91% (b) 180,800,000 209,301,000 494,847,000 15
180,800 704,148 63,086 5,880 5,880 180,800 704,148 5,880 68,966 1.02%2.08% 6 186,680 773,114 9. 193,590 63,227 13,817 63,227 207,407 16
10. 36,555 36,207 395,335 329,923 229,969 88,668 193,590 139,682 16,071 74,664 73,434 51,200 4,800 47,970 36,638 30,000 185,000 20,000 47,504 83,265 1,253,107 867,368 6 29,287 30,078 6 1 1,203 711 1 6,065 5,418 36,555 36,207 12 17
11. 4,732,700 3,042,531 16,641 3,454 3,079 2,371 19,720 5,825 407,408 260,472 2,747 2,742 1,021 10,419 105 14,590 (8,263) (2,163) (4,012) (14,654) 399,006 271,406 18
12. 31,990 15,379 4 51,638 38,575 83,628 53,954 2,046,769 1,209,945 742,578 561,675 240,465 122,679 4 91,743 49,125 76,654 47,267 71,438 32,947 56,506 17,278 44,987 22,307 42,725 39,789 22,067 25,501 21,331 5,343 18,348 7,810 16,096 3,410 13,184 13,384 8,115 3,930 4 6,979 12,502 3,565 3,350 1,639 809 80,527 39,002 3,689,344 2,272,007 19
13. (567) (340) (8,058) (6,983) (8,625) (7,323) 23,179 4,618 97,708 126,838 120,887 131,456 112,262 124,133 14. 89,610 419,986 167,758 (175,987) 257,368 243,999 20
1,567,451 1,165,541 25%25% 391,863 291,385 33,000 32,000 (5,609) (4,482) (24,708) (131,157) (56,123) (122,751) 81,597 5,693 4,687 3,605 2,367 257,368 243,999 15. (a) 1,303,012 904,402 5,175,024 5,175,024 25.18 17.48 (b) 21
16. 522,677,000 662,404,000 108,824,000 1 0.01 1 17. (a) 310,748 476,810 20,481 19,003 331,229 495,813 (b) 5,333 780 900 860 1,200 2,100 7,433 3,740 22
(I) (1) (2) 55.6% 4,732.7 44.1% 1,303.0 9.3% (1) (2) 23
(i) 80 320 GM1 696,067 1,343,922 93.1% 29.8% 649,636 1,115,331 71.7% 24.8% 123,360 170,327 38.1% 3.8% 361,213 432,468 19.7% 9.6% 217,098 219,827 1.3% 4.9% 205,475 328,451 59.8% 7.3% 125,902 195,062 54.9% 4.3% 24
B(II) 93,010 97,609 4.9% 2.2% 92,485 103,555 12.0% 2.3% 73,531 239,485 225.7% 5.3 B 73,121 134,489 83.9% 3.0% 67,019 75,794 13.1% 1.7% 25
60.7% 4,505.0 95.2% 71.7% 1,115.3 93.1% 1,343.9 225.7% 83.9% 59.8% 54.9% 19.7% 239.5 134.5 328.5 195.1 432.5 80% GM1 12.0% 13.1% 4.9% 1.3% 103.6 75.8 97.6 219.8 9.3% 26
(ii) 13,675 14,616 6.9% 6.4% 58,205 72,910 25.3% 32.0% 52,753 52,214-1.0% 22.9% 14,436 17,674 22.4% 7.8% 35,542 31,065-12.6% 13.6% 6.9% 14.6 22.4% 1.0% 69.9 25.3% 72.9 12.6% 31.1 27
(iii) a) 2,000 20,000 b) 28
10 (iv) 20,000 (a) 1.1 IND 1 1.1 1.1 DPP-4 II 29
1.1 (PPI) 1.1 pan-her FDA III II 1.3 IV NeuroVive Pharmaceutical AB to-bbb technologies B.V. (b) 3.1 3.1 17 3.1 22 30
(v) GMP 300,000 1.5 Apotex Inc. FDA FDA GMP FDA (II) (i) GMP 31
(ii) 10 32
(iii) (III) 3,042.5 55.6% 4,732.7 4,505.0 60.7% 95.2% 59.7 31.7% 40.8 0.9% 12.1% 175.2 3.7% 1,033.0 21.8% 33
2,289.4 61.6% 3,699.7 75.2% 78.2% 271.4 399.0 77.5% 2,329.5 206.6 58.2% 326.8 124.1 112.3 1,165.5 34.5% 1,567.5 244.0 5.5% 257.4 34
921.5 42.2% 1,310.1 17.1 10.0 7.1 904.4 44.1% 1,303.0 1,508.1 1,543.9 233.7 898.6 776.1 717.9 774.0 774.0 2.1 776.1 611.1 35
1,508,076 1,543,907 (186,680) (773,114) 1,321,396 770,793 1,398.0 923.3 474.7 101.3 91.5 18.9 18.4 1,441.7 517.6 56.0% 36
2,880.6 3,735.0 1,253.1 385.7 331.2 37
38
180.8 1,168.6 846.1 234.5 88.0 2,560 240.5 122.7 39
25% A.2.1 40
3.21 41
28 26 183 22 42
2.1 1 0.01 1 4.3 6.4 28 26 183 22 43
(www.sihuanpharm.com) (www.hkexnews.hk) 44