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Transcription:

00

-------------------------------------2 -----------------------------3 -----------------------4 ---------------------------6 ---------------10 ---------------------------------14 -----------------------------16 -----------------------------------19 -----------------------------------29 -------------------------------------31 -----------------------------------32 -------------------------------71

1 Hubei Biocause Pharmaceutical Co.,Ltd. Biocause Pharma 2 3 132 0724-2223218 0724-2217652 baikeyaoye@biocause.net 4 132 448000 http://www.biocause.com baikeyaoye@biocause.net 5 http://www.cninfo.com.cn 6 000627 7 1993 11 18 122 2003 4 22 132 4200001000001 42080127175001-4 1056 8

1 : 5,007,134.84 5,090,410.34-7,824,805.25 51,637,882.40 2,755,640.43-6,422,417.41 4,703,248.35 5,047,092.28 1,679,211.62 56,066,244.43-38,658,105.46 1 1,987,399.66 2-733,220.36 3 4,500,000.00 4 2,281,950.50 5 4,185,676.52 6 693,409.27 12,915,215.59

2 2004 2003 2002 463,045,597.85 422,678,621.88 348,610,268.02 5,090,410.34-48,105,953.24 5,260,847.93 1,081,321,681.31 1,090,972,350.77 1,090,403,517.26 ( ) 650,942,560.15 645,852,149.81 693,958,103.05 ( ) 0.009-0.08 0.01 ( ) 0.009-0.08 0.01 1.09 1.09 1.17 1.05 1.04 1.15 0.09-0.04-0.12 % 0.78-7.45 0.76 % 0.79-7.18 0.76-1.21-8.13 0.79 3 594,794,933.00 36,440,555.92 56,312,480.49 26,261,523.50-41,695,819.60 645,852,149.81 793,757.12 396,878.56 5,090,410.34 5,884,167.46 793,757.12 793,757.12 594,794,933.00 36,440,555.92 57,106,237.61 26,658,402.06-37,399,166.38 650,942,560.15 5,090,410.34.

1 + - 1131,619,377 131,619,377 127,174,322 127,174,322 4,445,055 4,445,055 2 292,065,591 292,065,591 3 4 423,684,968 423,684,968 1 171,109,965 171,109,965 2 3 4 171,109,965 171,109,965 594,794,933 594,794,933 2 1 1 2001 12 31, 517,212,986 2) 2002 6 5 2001 2001 517,212,986, 10 0.5 10 1, 594,794,933 3) 2003 3 7 247,174,322 12,000

2 3 1 2004 12 31 41208 2 2004 12 31 41208 0 172,288,348 28.97 12,500,000 0 127,174,322 21.38 100,000,000 27,174,322 100,000,000 0 63,221,250 10.63 63,221,250 0 42,150,720 7.09 42,150,720 0 6,173,689 1.04 0 4,445,055 0.75 0 2,057,895 0.35 0 2,057,895 0.35 0 1,755,868 0.3 0 1,028,947 0.17 5% 5% 1250 2001 10 15 10000 2002 1 4 2002 1 8 12717.4322 2003 3 21 2717.4322 2003 9 5, 10000

63,221,250 42,150,720 2003 3 28 2003 4 17 3 1 1001-1005 2000 1 25 4 27555 83.50%, 1963 11 28 2000 1 83.50% 28.97% 5 10% 2004 12 31 ( ) 127,174,322 21.38

19170.16 2000 4 28 63,221,250 10.63% 1049 2001 3 1 : 5 2004 12 31 (A B H ) 1 970,000 A 2 700,000 A 3 623,301 A 4 562,600 A 5 480,000 A 6 317,000 A 7 316,250 A 8 303,000 A 9 291,660 A 10 264,300 A

1 42 2003.4-2006.4 0 0 34 2003.8-2006.4 0 43 2004.6-2006.4 0 0 33 2003.4-2006.4 0 0 41 2003.4-2006.4 0 0 36 2003.4-2006.4 0 0 35 2004.12-2006.4 42 2003.4-2006.4 0 0 41 2003.4-2006.4 0 0 35 2003.4-2006.4 0 0 43 2003.4-2006.4 0 0 40 2003.4-2006.4 0 0 38 2003.4-2006.4 0 0 38 2004.11-2006.4 0 0 : 2000.7-2004.5-2 : (1) (2) (3)

(4) (5) (6) (7) 1992 1999 1999 2003 : (1) (2), (3) (1) (2) (3) (4)

3 1 2003 4 28 2003 30 ( ) 1 / 5 2003 4 28 2003 4 2 0.5 / 2 3 114 40 42 3 5 / 10 2 5 10 6 1 5 5 4

2004 6 30 00 2004 12 24 00 2004 12 13 2004 6 30 00 2004 4 30 2004 7 1 2004 12 24 00 5 2004 12 31 ( ) 1743 (1) (%) 142 8.15 34 1.95 65 3.73 47 2.70 1455 83.47 1743 100 (2) (%) 8 0.46 71 4.07 272 15.61 374 21.46 1018 58.41 1743 100 2

1 2 3 4 5 2004 12 24 00 2004,

1 13 12 0 1 13 12 0 1 14 13 1 0 14 14 0 0 1 1 0 0 2 1 2 3 4 5

2003 2004 2004 3 2003 2004 4 16 2004 5 21 4 404,834,640 68.06 % 1 2003 2 2003 3 2003 4 2003 5 2003 2003-41,695,819.60 2003 6 2003 2003 7 2004 8 < > 2003 2004 5 22 2004 2004 5 28 2004 6 30 2 299,462,670 50.35 %

(1) 1 2 3 4 (2) < > 1 2 2004 2004 7 1 2004 2004 11 23 2004 12 24 132 2 299,462,670 50.35 % 2 299,462,670 50.35 % 0 0 0 % (1) 1 2 3 (2)

(3) 2004 2004 12 25

1,, 2003 FDA FDA FDA 2004

1800 75 90, VB6 2 1 30,630.46 66.15 2,703.56 52.36 15,674.10 33.85 2,543.71 49.26 83.49-1.62 46,304.56 100 5,163.79 100 2 268,607,506.73 23,692,847.93 88,285,408.29 7,050,545.11 12,342,516.76 8,360,956.01 3 : 768.41 1.66 174.58 3.38

1,761.35 3.80 235.93 4.57 15,988.23 34.53 1,655.85 32.07 4,108.22 8.87 434.01 8.40 2,636.38 5.69 258.20 5.00 15,149.96 32.72 1,979.69 38.34 387.94 0.84 66.78 1.29 40,800.49 88.11 4,805.02 93.05 5,504.07 11.89 442.25 8.56-1.62 83.49 46,304.56 100.00 5,163.79 100.00 4 10% 1 175,290,664.06 158,975,200.52 9.31% 37.86% 2 93,316,842.67 85,939,458.28 7.91% 20.15% 3 20,570,558.31 19,622,022.37 4.61% 4.44% 5 A : 1 18,000.8 75%, 35014.26 2 1,579.75 95% 3764.36 3 1,000 98% 4480.67 4, 1000,

95%, 2675.62 5, 500, 95%, 948.11 B 1 7,500 83.6% 16797.09 2 1400 80% 1960.24 3 1000 97.75% 12376.63 30.14 7909.23 17.08 1 2 3 4 2004 2004 5 2004

6 3 GMP 4 % 463,045,597.85 422,678,621.88 9.55 51,637,882.40 40,416,528.52 27.76 5,090,410.34-48,105,953.24 110.58-38,658,105.46-16,824,749.22-129.77 1,081,321,681.31 1,090,972,350.77-0.88 650,942,560.15 645,852,149.81 0.79 1 9.55%, 2

3 1 2,, 3 : A 2003 B,, C 4 5 4-38,658,105.46, 5 2005 1 2005 2 FDA FDA 3

4 6 1) 2004 2 27,11 : 2004 2 28 2) 2004 3 2,10 2004 3 3 3) 2004 3 11, 3700 2004 3 13 4) 2004 4 13 9 00 10 9, 2003 2003 2003 2003 2003 < > 2003 2004 4 16 5) 2004 4 23 10 10

2004 6) 2004 4 30, : < > 2004 5 10 7) 2004 5 26 4000 2004 5 29 8) 2004 7 1, : 2004 7 2 9) 2004 7 26 2004 2004 7 28 10) 2004 8 3,,, 15,000, 13,000,2000, ( ), 2004 8 4 11) 2004 10 19 2004 12) 2004 11 22

2004 2004 11 23 13) 2004 12 13 14) 2004 12 28 4398 94.75 3 7 2004 2004 1 2004 5,090,410.34-41,695,819.60 2004-36,605,409.26 5 396,878.56, 5% 396,878.56-37,399,166.38 2 2004 36,440,555.92, 57,106,237.61 8 2003

9 1) (2005) 027 2004 [2003]56 : 25,500.000.00 26,500,000.00-1,000,000.00 663,598.47 6,168,899.63 6,008,642.04 823,856.06 2004 12 31 [2003]56 2 50%

1 2004 4 13 11 00 3 3 1 2003 2003 2 2003 2003 2004 4 23 3 3 2004 2004 7 26 2004 2004 10 19 3 3 2004 2004 12 13

2 1 2 2004 3 4 5 6

1 2 1 2004 2 27 60 613.1 2 2004 5 24 70% 945.16 450 3 2004 12 28 4398 94.75, 4188 448.84 2 3 4 1 2 300 3 5 5% 6 50 9 7 8 9

(2005) 0142 2004 12 31 2004 2004 2004 12 31 2004 2005 2 22

00 2004 12 31 1 16,833,054.99 55,491,160.45 10,104,715.73 9,835,344.15 2 3,009,600.00 6,413,210.00 600,000.00 272,000.00 3 48,718,250.04 81,266,581.77 8,622,273.06 34,674,997.95 4 130,942,519.88 169,250,687.89 120,611,249.34 99,371,930.01 5 93,289,127.66 29,040,981.58 44,570,737.31 16,177,219.25 6 128,615,900.68 125,760,745.54 26,358,071.11 51,969,262.20 319,652.05 673,749.78 79,937.36 166,457.37 421,728,105.30 467,897,117.01 210,946,983.91 212,467,210.93 7 127,277,420.55 94,034,888.89 450,406,976.11 405,801,373.52 127,277,420.55 94,034,888.89 450,406,976.11 405,801,373.52 127,277,420.55 94,034,888.89 450,406,976.11 405,801,373.52 8 496,080,927.34 503,766,469.97 125,646,360.48 196,316,815.84 8 189,075,671.27 161,446,798.22 59,076,045.43 74,093,155.08 307,005,256.07 342,319,671.75 66,570,315.05 122,223,660.76 8 11,477,689.90 11,477,689.90 3,511,821.54 3,511,821.54 295,527,566.17 330,841,981.85 63,058,493.51 118,711,839.22 3,643.00 61,227.68 9 47,737,339.69 7,539,346.02 38,572,877.01 3,535,189.35 343,268,548.86 338,442,555.55 101,631,370.52 122,247,028.57 10 186,789,280.52 189,075,072.03 140,415,274.88 153,532,713.39 11 2,258,326.08 1,522,717.29 189,047,606.60 190,597,789.32 140,415,274.88 153,532,713.39 1,081,321,681.31 1,090,972,350.77 903,400,605.42 894,048,326.41

00 2004 12 31 12 251,400,000.00 284,440,000.00 169,900,000.00 203,500,000.00 721,400.00 13 50,965,923.78 24,961,551.16 10,199,482.93 3,752,663.24 14 22,721,517.89 19,304,122.15 2,972,113.98 10,514,605.56 1,260,477.79 1,774,432.93 647,216.95 657,494.11 2,241,514.02 1,159,460.04-600,154.29-1,138,841.23 15 81,868.51 81,868.51 81,868.51 81,868.51 16 2,077,757.77 6,504,809.61 2,460,934.15 2,640,980.13 17 281,328.55 141,750.43 167,524.72 27,295.02 18 25,841,041.06 26,769,280.47 58,833,707.80 17,330,271.84 19 535,334.70 6,358,457.21 1,912,864.16 357,406,764.07 372,217,132.51 244,662,694.75 239,279,201.34 357,406,764.07 372,217,132.51 244,662,694.75 239,279,201.34 72,972,357.09 72,903,068.45 20 594,794,933.00 594,794,933.00 594,794,933.00 594,794,933.00 21 36,440,555.92 36,440,555.92 36,440,555.92 36,440,555.92 22 57,106,237.61 56,312,480.49 57,106,237.61 56,312,480.49 37,034,936.28 26,261,523.50 28,553,118.81 26,261,523.50 23-37,399,166.38-41,695,819.60-29,603,815.86-32,778,844.34 650,942,560.15 645,852,149.81 658,737,910.67 654,769,125.07 1,081,321,681.31 1,090,972,350.77 903,400,605.42 894,048,326.41

00 2004 24 463,045,597.85 422,678,621.88 220,319,159.45 163,345,791.20 24 410,572,863.46 380,848,332.50 201,113,168.33 158,135,688.43 834,851.99 1,413,760.86 414,906.45 537,367.07 51,637,882.40 40,416,528.52 18,791,084.67 4,672,735.70 25 2,755,640.43 3,742,661.30 1,925,496.89 2,412,808.09 17,574,919.17 32,274,982.83 1,479,475.73 816,452.69 32,349,041.33 49,679,106.90 12,887,986.12 25,126,059.55 26 10,891,979.74 15,497,104.11 6,055,742.93 11,173,900.86-6,422,417.41-53,292,004.02 293,376.78-30,030,869.31 27 4,703,248.35 8,219,342.66 1,541,319.28-18,508,680.06 28 5,047,092.28-2,000,000.00 2,509,835.90 12,624.47 192,755.06 6,350.00 830,624.28 2,248,879.36 58,665.52 694,378.61 5,007,134.84-47,308,916.25 3,968,785.60-49,227,577.98 72,435.86 1,738,560.63-155,711.36-941,523.64 5,090,410.34-48,105,953.24 3,968,785.60-49,227,577.98-41,695,819.60 6,410,133.64-32,778,844.34 16,448,733.64-36,605,409.26-41,695,819.60-28,810,058.74-32,778,844.34 396,878.56-396,878.56 396,878.56-396,878.56-37,399,166.38-41,695,819.60-29,603,815.86-32,778,844.34-37,399,166.38-41,695,819.60-29,603,815.86-32,778,844.34 1 4,500,000.00 2 3 4 5 6

00 2004 2003 % % 7.93% 7.96% 0.087 0.087 6.26% 6.03% 0.068 0.068-0.99% -0.99% -0.011-0.011-8.25% -7.96% -0.090-0.090 0.78% 0.79% 0.009 0.009-7.45% -7.18% -0.081-0.081-1.20% -1.21% -0.013-0.013-8.43% -8.13% -0.092-0.092

00 2004 1 584,157,702.77 311,855,538.87 2 2,643,279.88 3 81,842,414.87 127,338,837.34 4 668,643,397.52 439,194,376.21 5 529,816,277.52 268,061,794.85 6 34,054,678.23 11,932,360.28 7 17,216,377.35 6,676,768.62 8 31,489,819.99 63,277,768.70 9 612,577,153.09 349,948,692.45 10 56,066,244.43 89,245,683.76 11 11,082,636.01 11,082,636.01 12 4,500,000.00 4,500,000.00 13 2,754,500.00 450,000.00 14 15 18,337,136.01 16,032,636.01 16 25,520,295.09 12,512,560.86 17 39,000,000.00 49,365,000.00 18 19 64,520,295.09 61,877,560.86 20-46,183,159.08-45,844,924.85 21 22 202,400,000.00 150,400,000.00 23 24 202,400,000.00 150,400,000.00 25 235,440,000.00 184,000,000.00 26 15,511,308.29 9,531,387.33 27 28 250,951,308.29 193,531,387.33 29-48,551,308.29-43,131,387.33 30 10,117.48 31 32-38,658,105.46 269,371.58

00 1 33 5,090,410.34 3,968,785.60 34-155,711.36 35-3,939,054.47-2,687,389.70 36 28,973,357.32 10,192,800.19 37 6,913,082.95 3,223,940.37 38 285,280.53 39 354,097.73 86,520.01 40-5,823,122.51-1,912,864.16 ( ) 41-2,266,373.24 38,126.76 42 43 10,891,979.74 6,055,742.93 44-4,703,248.35-1,541,319.28 45 46-1,845,090.66-25,611,191.09 ( ) 47 10,011,963.66 56,536,174.56 ( ) 48 12,278,672.75 40,896,357.57 49 50 56,066,244.43 89,245,683.76 2 51 52 53 3 54 16,833,054.99 10,104,715.73 55 55,491,160.45 9,835,344.15 56 57 58-38,658,105.46 269,371.58

00 2004 % 2004 2004 2004 2004 7.93% 7.96% 0.087 0.087-0.99% -0.99% -0.011-0.011 0.78% 0.79% 0.009 0.009-1.20% -1.21% -0.013-0.013 2,509,835.90 522,436.24 1,987,399.66-830,627.28-97,406.92-733,220.36 4,500,000.00 4,500,000.00 2,281,950.50 2,281,950.50 5,047,092.28 861,415.76 4,185,676.52 1,010,064.48 316,655.21 693,409.27 14,518,315.88 1,603,100.29 12,915,215.59 = / = / =P/(Eo+Np/2+Ei*Mi/Mo-Ej*Mj/Mo) =P/(So+S1+Si*Mi/Mo-Sj*Mj/Mo) 51,637,882.40-6,422,417.41 P 5,090,410.34-7,824,805.25 NP 5,090,410.34 Eo 645,852,149.81 Ei Ej Mo 12 Mi Mj So 594,794,933.00 S1 Si Sj Mo 12 Mi Mj 650,942,560.15 594,794,933.00

00 2004 11,066,187.23 2,928,989.99 2,928,989.99 8,137,197.24 4,075,002.06 2,159,851.39 2,159,851.39 1,915,150.67 6,991,185.17 769,138.60 769,138.60 6,222,046.57 2,396,684.90 1,010,064.48 1,010,064.48 1,386,620.42 2,384,265.66 998,329.13 998,329.13 1,385,936.53 12,419.24 11,735.35 11,735.35 683.89 11,477,689.90 11,477,689.90 8,345,891.15 8,345,891.15 119,948.08 119,948.08 2,390,615.10 2,390,615.10 621,235.57 621,235.57 24,940,562.03 3,939,054.47 3,939,054.47 21,001,507.56

00 ( 2000 7 17 ) 1993 1996 10 25 (1996)291 1996 10 31 1,112.20 5,162.20 1996 12 23 [1996]20 1:1 10,324.40 1998 6 5 [1998]60 10,324.40 10 3 510.12 2,587.2 12,911.60 1999 8 31 1999 6 30 12,911.60 10 8 23,240.88 2000 4 28 1999 23,240.88 10 2 4,648.176 27,889.056 2001 2 [2000]219 1,014 28,903.056 2001 5 2000 2000 27,889.056 10 2 0.5, 5,577.8098, 34,480.8658 2001 9 2001 2001 6 30 34,480.8658 10 5 17,240.4328 51,721.2986 2002 5 30 2001 2001 51,721.2986 10 0.5 0.125, 1, 59,479.4933 4200001000001

00 132 ( ) 1 2 1 1 12 31 3 4 5 6 7 (1) A

00 B C D (2) (3) (4) 8 (1) (2) (3) 1 1 3% 1 5% (4)

00 A B C 9 (1) (2) (3) (4) (5) (6) 10 (1) A

00 B C (2) 20%( 20%) 20% 20% (3) 10 (4) (5) 2 1 1 2

00 (6) : 11 (1) (2) (3) 12 (1) (2)

00 30% (3) % % 18 38 4 5.34-2.53 5-14 4 19.2-6.86 8-10 4 12-9.6 6-8 4 16-12 5-10 4 19.2-9.6 (4) (5)

00 13 (1) (2) (3) 14 (1) (2)

00 10 40 44 50 20 10 (3) 15 16 (1) (2) A B C (3) (4) 3

00 17 (1) : (2) (3) 18 19 1995 11 1996 2 20 (1) 17% (2) 5% (3) 7% (4) : 3% (5) 33%, [1999]172 15% 2001-2003 15%,

00 30% 33% 33% 33% 33% 1 % 1. 7,500.00 6,294.99 83.60 2. 18,000.80 14,030.90 75.00 3. 1,578.95 1,498.78 95.00 4. 1,000.00 3,035.84 98.00 5. 1,000.00 950.00 95.00 6. 500.00 475.00 95.00 7. 1,000.00 991.69 97.75 2 % 1. 1,400.00 1,120.00 80.00 1,960.24 34.75 0.80 2. 4,188.00 4,398.00 94.75 4,188.00 0.00 0.00 (1) 1996 2 10% (2) 7 2 (3) 2004 2 27 60% 6,131,025.12 (4) 2004 5 24

00 70% 9,451,610.89 3 2004 1 1,000.00 97.75%, 1 113,305.69 252,075.63 16,371,014.32 53,176,550.35 348,734.98 2,062,534.47 16,833,054.99 55,491,160.45 (1) 69.67% (2) (3) 2 3,009,600.00 6,413,210.00 :(1) 2,109,600.00 900,000.00 ; (2) 3 (%) % 1 30,825,969.21 61.00 924,779.07 34,513,231.98 40.44 1,035,396.96 1 2 10,370,477.82 20.00 518,523.90 32,506,691.37 38.09 1,625,334.57 2 3 1,848,305.28 4.00 92,415.27 9,582,837.86 11.23 479,141.89

00 3 7,588,648.40 15.00 379,432.43 8,738,822.61 10.24 935,128.63 50,633,400.71 100.00 1,915,150.67 85,341,583.82 100.00 4,075,002.05 (1) 5%( 5%) (2) 12,785,505.74 25.25% (3) 40.67% 4 (%) % 1 31,809,087.44 23.00 954,272.64 91,045,424.88 51.66 2,731,362.76 1 2 69,604,847.61 51.00 3,480,242.38 28,221,822.01 16.01 1,411,091.10 2 3 18,250,231.18 13.00 912,511.55 39,945,918.33 22.67 1,997,295.92 3 17,500,400.22 13.00 875,020.00 17,028,707.84 9.66 851,435.39 137,164,566.45 100.00 6,222,046.57 176,241,873.06 100.00 6,991,185.17 (1) 21.38% 823,856.06 (2) 57,781,799.07 42.16% (3) 22.17% 5 (%) (%) 1 90,176,043.83 96.66 27,433,179.05 94.46 1-2 2,732,079.35 2.93 1,266,384.87 4.36 2-3 5,707.80 0.01 297,749.66 1.03 3 375,296.68 0.40 43,668.00 0.15 93,289,127.66 100.00 29,040,981.58 100.00

00 (1) 5% 5% (2) 221.23%, 6 63,169,528.04 876,326.22 50,199,769.58 12,419.24 54,425,142.99 510,294.20 73,633,081.83 2,384,265.66 1,841,067.99 10,523,056.62 4,280,437.28 43,725.46 44,141.75 130,002,521.10 1,386,620.42 128,157,430.44 2,396,684.90 7 (1) (%) + - 50 60 6,330,166.80 6,131,025.12-6,131,025.12 0.00 (4) 20 80 11,200,000.00 12,441,061.62 7,902.89 1,248,964.51 12,448,964.51 20 70 7,361,602.15 4,951,610.89-4,951,610.89 0.00 (5) 20 8 20,000,000.00 20,000,000.00 20,000,000.00 30 10 2,000,000.00 2,000,000.00 2,000,000.00 94.75 39,681,300.00 39,681,300.00 39,681,300.00 (2) 20 31.25 50,000,000.00 50,089,342.53 35,859.88 125,202.41 50,125,202.41

00 136,573,068.9 95,613,040.16 39,681,300.0000 43,762.77-11,082,636.01 1,374,166.92 124,255,466.9 (2) 1,781,725.67 10 1,425,380.47 178,172.63 1,247,207.83-3,746,633.76 10-3,003,531.74-374,663.38-2,628,868.36 (1) 141,919.32 10 1,182.66 140,736.66 (3) 4,298,700.00 10 35,822.50 4,262,877.50 2,475,711.23-1,578,151.27-159,485.59 3,021,953.63 (1) 2001 12 1 (2) 2004 12 25, 94.75% 2004 12 25, 3,980.00, 429.87, (3) 2004 1 1,000.00 97.75% 14.19 (4) 2004 2 27 60% 6,131,025.12 (5) 2004 5 24 70% 9,451,610.89 4,951,610.89, 4,500,000.00

8 (1) 00 159,743,635.69 22,488,217.48 46,551,521.53 135,680,331.64 277,149,045.21 22,411,703.46 5,935,890.02 293,624,858.65 36,415,729.51 45,723.00 36,461,452.51 12,869,102.11 1,871,996.61 1,502,195.64 13,238,903.08 17,588,957.45 46,892.47 560,468.46 17,075,381.46 503,766,469.97 46,864,533.02 54,550,075.65 496,080,927.34 (2) 24,457,871.44 3,560,650.41 198,048.14 27,820,473.71 105,782,398.39 19,022,121.01 48,153.99 125,311,542.20 20,159,656.18 3,429,689.09 21,984,168.48 5,520,337.05 1,267,196.22 1,009,801.82 6,247,731.45 5,526,535.16 1,693,700.59 88,480.32 7,711,755.43 161,446,798.22 28,973,357.32 1,344,484.27 189,075,671.27 342,319,671.75 307,005,256.07 (3) 8,345,891.15 8,345,891.15 119,948.08 119,948.08 2,390,615.10 2,390,615.10 621,235.57 621,235.57

00 11,477,689.90 11,477,689.90 (1) 30,518,750.44 (2) 12 (3) 9 ( ) 2,900 4,161,372.29 4,161,372.29 23,869.70 23,869.70 4,000 691,323.63 691,323.63 380 3,081,867.85 893,575.40 1,025,493.38 2,949,949.87 ( ) 157,684.86 20,259.87 146,020.26 31,924.47 291,653.28 291,653.28 2,169,308.54 2,169,308.54 22,293,076.45 22,151,192.9 141,883.52 369,578.91 369,578.91 391,565.60 19,239.63 410,805.23 359,280.00 321,175.00 680,455.00 310 13,758.36 59,507.26 73,265.62 43,821.46 43,821.46 132,246.47 132,246.47 13,324.99 12,377.00 25,701.99 2,799,195.45 2,788,291.47 10,903.98 2,203,187.55 2,203,187.55 1,227,668.90 1,227,668.90 APSAC 1,811,470.00 1,811,470.00 27,904,090.60 350,000.00 27,554,090.60 6,790,611.08 1,174,109.85 5,616,501.23 7,539,346.02 70,716,744.11 30,518,750.44 47,737,339.69

00 : 10 5,620,000.00 3.178.412.03 231,438.12 2,673,026.09 2,946,973.91 14 37,424,720.39 30.726.073.29 7,016,750.43 2,967,200.00 3,763,305.92 14,929,698.45 31,012,317.80 14-15 167,280,033.32 153.540.648.49 225,000.00 2,618,288.08 16,357,672.91 151,147,360.41 46-47 1,100,000.00 511.545.97 37,393.52 625,847.55 474,152.45 9 1,258,589.66 962.992.22 62,157.48 357,754.92 900,834.74 14 4,046,552.14 155.400.03 365,060.00 12,318.99 200,499.83 392,859.29 307,641.21 3-10 216,729,895.51 189,075,072.03 7,606,810.43 2,979,518.99 6,913,082.95 35,336,859.21 186,789,280.52 11 GMP 1,522,717.29 1,522,717.29 242,743.47 242,743.47 1,279,973.82 4 1,020,889.32 1,020,889.32 42,537.06 42,537.06 978,352.26 4 2,543,606.61 1,522,717.29 1,020,889.32 285,280.53 285,280.53 2,258,326.08 12 248,400,000.00 116,500,000.00 3,000,000.00 164,640,000.00 3,300,000.00 251,400,000.00 284,440,000.00 1 24,840 11 300 16 091 (

00 3 ) 13,240 13 670 300 454.48 2 300 300 13 24,961,551.16 50,965,923.78 (1) 5% 5% (2) 104.18% 14 19,304,122.15 22,721,517.89 5% 5% 15 81,868.51 16 81,868.51 % 329,812.17 5,012,404.33 17-1,256,171.56-708,345.32 33 15 480,116.07 163,659.27 7 122,986.92 0.32 5 1,970,696.31 1,970,696.31 430,317.86 66,394.70 2,077,757.77 6,504,809.61 17

00 % 303,403.30 168,073.55 3 986.06-2,649.27-23,060.81-23,673.85 281,328.55 141,750.43 18 26,769,280.47 25,841,041.06 28.97% 1,000,000.00 19 644,501.90 53,012.83 333,844.97 356,810.17 117,159.65 3,000,365.37 1,194,844.10 8,352.05 1,184,900.87 535,334.70 6,358,457.21 20 + - 1423,684,969 423,684,969

00 127,174,322 127,174,322 296,510,647 296,510,647 423,684,969 423,684,969 171,109,964 171,109,964 594,794,933 594,794,933 21 24,380,434.09 24,380,434.09 12,060,121.83 12,060,121.83 36,440,555.92 36,440,555.92 22 26,261,523.50 396,878.56 26,658,402.06 26,261,523.50 396,878.56 26,658,402.06 3,789,433.49 3,789,433.49 56,312,480.49 793,757.12 57,106,237.61 23 5,090,410.34-41,695,819.60 396,878.56 396,878.56

00-37,399,166.38 24 306,304,566.52 263,141,778.68 279,268,980.39 240,158,811.67 156,741,031.33 159,536,843.20 131,303,883.07 140,689,520.83 463,045,597.85 422,678,621.88 410,572,863.46 380,848,332.50 1 9.68%, 2 2003 3 7,909.23 17.08% 25 (1) 16,344,516.90 26,504,135.46 1,756,780.02 893,320.61 141,120.00 1,174,307.01 129,604.03 19,416,723.93 27,527,060.10 (2) 14,699,549.27 23,617,964.83 7,761.60 1,953,772.63 166,433.97 16,661,083.50 23,784,398.80

(3) 2,755,640.43 3,742,661.30 00 26.37% 26 13,918,308.29 15,476,763.89 3,241,152.10 165,626.12 10,599.61 41,640.56 204,223.94 144,325.78 10,891,979.74 15,497,104.11 27 451,828.13 43,762.77-440,087.84 159,485.58 196,490.75 8,011,111.62 4,500,000.00 4,703,248.35 8,219,342.66 7 (5) ; 28 5,047,092.28 (1) 2004 6, 2,000,000.00 (2) 2004 5,

00 [2004]17, 2,670,000.00 (3) 2004 2, 295,000.00 (4) 2004 6, 82,092.28 29 31,489,819.99 801,219.24 8,828,936.74 7,594,445.38 603,300.00 1,753,430.53 1,753,293.71 2,026,961.70 282,043.08 1,253,210.19 361,523.30 6,231,456.12 1 % (%) 1 7,742,695.84 88.88 40,917.58 15,139,777.10 42.15 208,369.95 1 2 5,640.00 0.06 282.00 18,874,160.00 52.54 943,708.00 2 3 316,288.38 0.88 15,814.42 3 963,301.89 11.06 48,165.09 1,592,278.78 4.43 79,613.94 8,711,637.73 100.00 89,364.67 35,922,504.26 100.00 1,247,506.31 2

00 (1) + - (%) 50 60 6,330,166.80 6,131,025.12-6,131,025.12-199,141.68 0.00 20 80 11,200,000.00 12,441,061.62 7,902.89 1,248,964.51 12,448,964.51 20 70 7,361,602.15 4,951,610.89-4,951,610.89-2,409,991.26 0.00 50 75 140,308,954.02 185,673,641.68 348,897.11 45,713,584.77 186,022,538.79 39 95 14,987,841.24 15,878,781.88 2,543,610.85 3,434,551.49 18,422,392.73 50 83.6 61,168,200.44 73,907,848.96-1,743,593.96 10,996,054.56 72,164,255.00 20 98 22,951,020.74 29,034,019.13-2,511,191.54 3,571,506.85 26,522,527.59 10 95 9,500,000.00-4,564,564.47 4,750,000.00 261,385.51-9,053,178.96 446,821.04 10 95 4,750,000.00 2,920,082.19-809,854.09-2,639,771.90 2,110,228.10 20 31.25 50,000,000.00 50,089,342.53 35,859.88 125,202.41 50,125,202.41 20 11.11 20,000,000.00 20,000,000.00 20,000,000.00 30 10 2,000,000.00 2,000,000.00 2,000,000.00 94.75 39,681,300.00 39,681,300.00 39,681.300.00 97.75 9,775,000.00 9,775,000.00-129,558.21-129,558.21 9,645,441.79 400,014,085.39 398,462,849.53 54,206,300.00-1,996,541.56-11,082,636.01 50,658,222.58 439,589,671.96 (2) 7,407,366.24 5,913,143.52 10 746,961.36 5,166,482.16 1,781,725.67 1,425,380.47 10 178,172.63 1,247,207.83 141,919.32 10 1,182.66 140,736.66 4,298,700.00 10 35,822.50 4,262,877.50 13,629,711.23 7,338,523.99 962,139.15 10,817,304.15 : 7

3 00 218,306,348.71 159,747,985.77 198,648,146.97 155,160,528.25 2,012,810.74 3,597,805.43 2,465,021.36 2,975,160.18 220,319,159.45 163,345,791.20 201,113,168.33 158,135,688.43 4 451,828.13-1,996,541.56-26,046,485.82 8,011,111.62 4,500,000.00-962,139.16-925,133.99 1,541,319.28-18,508,680.06 1 (1),, 1,

00,, 286,,,. 1, 1 2 C 502 (2) ( ) ( ) ( ) ( ) 33,000.00 33,000.00 7,500.00 7,500.00 1,400.00 1,400.00 18,000.80 18,000.80 1,578.95 1,578.95 1,000.00 1,000.00 500.00 500.00 1,000.00 500.00 500.00 1,000.00 1,000.00 4,188.00 4,188.00

00 (3) ( ) (%) ( ) (%) ( ) (%) ( ) (%) 17,228.8348 28.97 17,228.8348 28.97 6,270.00 83.6 6,270.00 83.6 1,120.00 80 1,120.00 80 13,500.60 75 13,500.60 75 1,500.00 95 1,500.00 95 980.00 98 980.00 98 475.00 95 475.00 95 950.00 95 475.00 95 475.00 95 977.50 97.75 977.50 97.75 3,968.13 94.75 3,968.13 94.75 (4) 2 (1) 2004 1 12 2003 1 12 (%) (%) 9,916,564.10 2.35 9,916,564.10 2.35

00 (4) 2004 2 27 60% 6,131,025.12 3 A (%) (%) 360,040.18 0.71 B (%) (%) 663,598.47 0.39 823,856.06 0.60 456,459.59 0.26 699,539.05 0.51 C (%) (%) 1,282,803.63 4.79 1,000,000.00 3.74

00 7,684.097.12 5,938,302.84 1,745,794.28 17,613,495.21 15,254,229.22 2,359,265.99 159,882,262.31 143,323,774.71 16,558,487.60 41,082,222.54 36,742,158.92 4,340,063.62 26,363,827.08 23,781,867.85 2,581,959.23 151,499,611.19 131,702,756.45 19,796,854.74 3,879,400.92 3,211,576.99 667,823.93 408,004,916.37 359,954,666.98 48,050,249.39 55,040,681.48 50,618,196.48 4,422,485.00 463,045,597.85 410,572,863.46 52,472,734.39 2004 2004

00 1 2 3 4 5 OO