)],generalhealthstatus[(68 8±13 4)vs.(58 2±12 8)]intheobservationgroupweresignificantly beterthaninthecontrolgroup(alp<0 05).Innut

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续强
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1 , :; 丁洁云蔡晓娟陈美 <, :; => ? A234BC,56-7,DE F GHIJKHL 50A GHMNO 2 PQIRS,JKHTUVW XY H7,56-89Z[; (QLQ C30) \ I ] ^_,56- H7 89Z[; (QLQ C30) \ I ]^_`abc ( P> 0 05),56 - J K H 7 [(75 6±13 1) (63 8±12 4) ] [(61 9±14 3) (52 5±13 7) ] [(36 6±13 2) (45 8±15 0) ] [(34 8±16 1) (44 3±17 0) ] [(49 2±15 7) (57 2±14 3) ] 2 [(50 2±16 2) (59 0±15 8) ] [ [(21 5±10 3) (29 9±11 3) ] [(68 8±13 4) (58 2±12 8) ]\ GH ( P<0 05);,56- JKH 7 :; [(59 3±8 5)kg (54 4±7 3)kg] :; [(21 9±2 1)kg/m 2 (18 4± 2 8)kg/m 2 ] [(125 9±8 9) g/l (107 3±9 5) g/l] [(35 1± 6 9)g/L (29 0±5 3)g/L] [(213 54±37 47)mg/L (174 56±36 26)mg/L] GH ( P<0 01) <, , S, 23 2 RS, 89:;,,56-23&';,5- ;23 ;89:;; :2012#$% b ( ) (HS12947) Theefectofcomprehensiveinterventiononthequalityoflifeofesophagealcancerpatientstreatedwith radiotherapy DingJieyun,CaiXiaojuan,ChenMei. DepartmentofInternalMedicine,NantongTumor Hospital,Nantong226361,China Corespondingauthor:CaiXiaojuan,E mail:[email protected] Abstract Objective Todiscustheefectofcomprehensiveinterventiononthequalityoflifeofesopha gealcancerpatientsreceivingradiotherapy.methods 100patientswithesophagealcarcinomatreatedwithradio therapyforthefirsttimewereselectedbetweenoctober2012anddecember2014innantongtumorhospitalin JiangsuProvinceandrandomlydividedintocontrolgroupandobservationgroup(n=50ineachgroup)witha randomnumbertable.inthecontrolgroup,routinedietaryinstruction,fluidinfusionsupportandsymptomaticin terventionwereused;comprehensiveinterventionwasaddedintheobservationgroup.scoresofcorequalityof lifequestionnaire(qlq C30)andnutritionalindexesbeforeandafterradiotherapyinthetwogroupswerecom pared.results TherewerenostatisticalysignificantdiferencesinQLQ C30scoresandnutritionalindexesbe tweenthetwogroupsbeforeradiotherapy(alp>0 05).Afterradiotherapy,thephysical[(75 6±13 1)vs. (63 8±12 4)]andemotionalfunction[(61 9±14 3)vs.(52 5±13 7)],fatigue[(36 6±13 2)vs. (45 8±15 0)],pain[(34 8±16 1)vs.(44 3±17 0)],insomnia[(49 2±15 7)vs.(57 2±14 3)], losofappetite[(50 2±16 2)vs.(59 0±15 8)],nauseaandvomiting[(21 5±10 3)vs.(29 9± DOI: /cma.j.isn X :226361!"#$%&' ( ( )*+),,- (./) $0 :)*+,E mail:[email protected]

2 )],generalhealthstatus[(68 8±13 4)vs.(58 2±12 8)]intheobservationgroupweresignificantly beterthaninthecontrolgroup(alp<0 05).Innutritionalstatus,bodyweight[(59 3±8 5)kgvs.(54 4± 7 3)kg],bodymasindex[(21 9±2 1) kg/m 2 vs.(18 4±2 8)kg/m 2 ],hemoglobin[(125 9± 8 9)g/Lvs.(107 3±9 5)g/L],albumin[(35 1±6 9)g/Lvs.(29 0±5 3)g/L],andprealbumin [(213 54±37 47)mg/Lvs.(174 56±36 26)mg/L]intheobservationgroupwerealhigherthanthosein thecontrolgroupafterradiotherapy(alp<0 01).Conclusion Comprehensiveinterventionforesophageal cancerpatientsreceivingradiotherapymayimprovenutritionalstatus,reduceesophagitis,thirsty,fatigue,losof appetiteandothersymptoms,improvethequalityoflife,ensurethecompletionofradiotherapy. Keywords Esophagealneoplasms;Radiotherapy;Esophagitis;Qualityoflife;Comprehensiveinter vention Fundprogram:TheProgramof2012NantongCitySocialUndertakingsScienceandTechnologyProject (Guidance)(HS12947) 234 O &', /2 X, B [1] 23 4 &',7 C 50% 6-, U, [2] 2347,-,E,-;, 823,7 2 RS, 7, 8,7!" 2 RS,,- #< $%,& R', 7 I ()*,+,-,-Y.-,- / [3] 01 MN -, 2 RS I[, 7 S,,-#<2, 7 8 9:;, -, => ? ,-7 100AF1 6 DE FJKHI GHL 50A,=] 7: c 89:;BC <;6,-,, -;b F 60~70Gy; O,7 O,`9 [< C ;Karnofsky\ (karnofskyperformancescore, KPS) 70,7 D &E 1 ]7:2346- F C ;GH!1 H7 I J 6-KL KPS V045,^_` abc ( P>0 05),M ( 1) 01 NO K H,- P?,-QR, STU V 2 GHMNO 2, QW 2XY,,- D &Z[ 2 \,] PQ c ^,-! 1 H7 345 Table1 Comparisonoftwogroupsofpatientswithgeneralinformation I (_) J (A) ` (A) HJ ab x±s c $ X GH (n=50) 44~ ± JKH (n=50) 46~ ± χ P HJ (A) Ⅰ Ⅱ Ⅲ,-; (Gy) KPS( ) GH (n=50) ~70 >70 JKH (n=50) ~70 >70 χ 2 P \:KPS:karnofsky\

3 F 76 2%, ' 8 5% [4] F 8 X,- 8 ', T 2, - J\ PQ,,-& R HT 2 K J\ $ :(1) F 23, 2 &Q 7,D:D; : : 2,, 3F 37 ; 8 2F 2 2 \, M> 2, 2$ 9 /, ;M> (2) 2 7 :1=, `,T,, /, b 27 B Q, T N &,, :0 9%8 100ml 5ml 5mg, 16 U 5~10ml, 7 (3) 2 : 2 2 T23,!" 23,- JKHN#$ %&' ; N, '! JKHT GH VWXY 2 T U V 7 ( 2, ; ), N * Q a (NCCW2009]7,),b- 1d ;,. /01 : 0 200~300ml, 2 F :/01 20g 2 : :;, :6/ / : < / 0 1 := >? < 6- IA S B 2C, D B2N K, EJ7 E 7 T,-!" 3~4,5 23, 2, 7, F 3,, GF3 ;/01, 37,H ZIJ ` [KLM NVO (17) (11%) \5,, + P,J ] FQPQ RS 7,- R8 2 RS ST F7 E I UV,W XY, V \ 7, ZT Q[ \]^, ;_ 7 \T 7, `,ab 7 I T] ^\, c A\, Q E ml X, Q 6 / / = 1~2E, </ *< < =< ;F ' 9, $, ^,7 ',, [,B T, -,T,,& <, 1 2 3,-QR,-QR,5 23?,5 <,7 2I 2F, 2 2, 2 ; 8 F, ;,;,! b,!,.7 O89 23 RS3, ;JKH [, 7,,B 0, MN, ( 6 8 / ) (, ) A - ( ) [5],\ U V,,7 D6- /, 7 0[! E, 7!" RS, JK ] :; N 4R1 6-H1, 89:;Z[ ; (EORTCQLQ C30)`,: 5E ; 3ERS ; 1E S ; I 6E RSI (S _, 15 S (89:;) 7E,\ 1~7 ; \ 4E : =1 =2 =3 O =4 5E ; I ; O 9 S,

4 RS; O 9RS,EORTCQLQ C30 `, 15E 0 T 0 73 X,L 0 α T 0 5 X, N 4R7 89:; [6 7], 7: \ 4 R7 89:;S ] JK H,-,- :; :; 1 4 abc ) T SPSS17 0ab X I,b;45 x±s, t, P<0 05F^_ abc H,- EORTCQLQ C30`,O H EORTCQLQ C30`,O ^_`abc (P>0 05) ( 2);,-Q R HT 2 [ S X ^ _ abc ( P<0 05), I O ^_ `abc ( P>0 05)( 3) 2 2 H,- ],- H ] ^_`abc ( P>0 05) ( 4);,- H ^_ abc ( P<0 01)( 5) 3 " S,, S,- &, 23 23, 2 R8 &, 4& U 7! 2 H,- EORTCQLQ C30`,O (x±s, ) Table2 ComparisonofEORTCQLQ C30scoresintwogroupsbeforeradiotherapy(x±s,scores) HJ D [ GH (n=50) 62 4± ± ± ± ± ± ±10 4 JKH (n=50) 65 6± ± ± ± ± ± ±11 1 t P HJ 2! "# ( S GH (n=50) 31 2± ± ± ± ± ± ± ±12 0 JKH (n=50) 29 6± ± ± ± ± ± ± ±11 0 t P \:EORTCQLQ C30: 4R6-H1, 89:;Z[;! 3 H,- EORTCQLQ C30`,O (x±s, ) Table3 ComparisonofEORTCQLQ C30scoresintwogroupsafterradiotherapy(x±s,scores) HJ D [ GH (n=50) 63 8± ± ± ± ± ± ±11 3 JKH (n=50) 75 6± ± ± ± ± ± ±10 3 t P HJ 2! "# ( S GH (n=50) 44 3± ± ± ± ± ± ± ±12 8 JKH (n=50) 34 8± ± ± ± ± ± ± ±13 4 t P \:EORTCQLQ C30: 4R6-H1, 89:;Z[;

5 ! 4 H,- ] (x±s) Table4 Comparisonofnutritionalindexesoftwogroupsbeforeradiotherapy(x±s) HJ BW (kg) BMI(kg/m 2 ) Hb(g/L) ALB (g/l) PA (mg/l) GH (n=50) 59 2± ± ± ± ±30 23 JKH (n=50) 58 4± ± ± ± ±31 03 t P \:BW: :;;BMI: :; ;Hb: ;ALB: ;PA:! 5 H,- ] (x±s) Table5 Comparisonofnutrtinalindexesoftwogroupsafterradiotherapy(x±s) HJ BW (kg) BMI(kg/m 2 ) Hb(g/L) ALB (g/l) PA (mg/l) GH (n=50) 54 4± ± ± ± ±36 26 JKH (n=50) 59 3± ± ± ± ±37 47 t P \:BW: :;;BMI: :; ;Hb: ;ALB: ;PA: : 2F 01 JKH7 0F ;2 2N 5 78 :; ; <8, / / /01F 2N, $I%2,&'&, [8] 2 \ K K I 2, -& R 8 2 7, 7, F 3 GF3 ;/01 /01 /, ; ;, 3 7, H ZIJ ` FQPQ, - ; 01,JKH7,- $ 2,7 S 9 GH (P<0 01), :; ]`,7 T 2 [ 9 GH (P<0 05), ,-7 S,7 ( #<,-, 7 89:;, OTX )* 3 2 RS 7,-!" [ 2 + RS,$ 2, ' /,-. =>?<8, -7 + I23 RS ,- O & R, 8 F 46 0% ~78 2% [9] 0H A23 8 F 80 5%, 0H A MN/, -6- JKH$ N# $ %&' ; 0 N, 18 N; ; N, 23 +, I 23 ;7 /,'- 8 ; *< < & ; < 4 N;= F2 6!,& < 3 ; / B F2!; 8 4 5;:;, % , -7 92NX:2, 2 [ RS [10] I I ; 7 UV8, RS $,JKH RS GH (P<0 05) 3 3 [! [ 7 [ 2,N>( 0VPQ S,- 7,5 R & R, 89:;$ %, 7 [ JKH$, 0 B [11], [, 7 6-<, 2=,$ ^ K,7 [, >, [ 2,6-

6 [1],.Q c[m].4,. : FG8!,,2007: [2]HIJ.K L, JK[J]. ^,2011,3(8):41 42.DOI: /j.isn [3]MNO ,- S [J].Q -,2014,33(6):53 54.DOI: /j.isn x [4].X &'7 S,56- + [D]. : c,2010. [5] P,QRS.[ &'b :; [12] 01 Q/, 7 T K 9 G H (P<0 01), 7 F! I! E,7 NO( C F D I0V,.7 X, 2347,- #<2,,- 7,,- \ JK, PQI R,& [,,-QR AB \7 RS F, CB,7 6-&D E6- /,89:;, ( N # $ % & [J].,2011,46(12): DOI: /j.isn [6] T,.9,UVW,.4R7 8X:; ; EORTCQIQ C30`,\ [J]. N&',2005,20 (4): DOI: /j.isn [7] IntermediateCare.Guidanceforcommisionersandprovidersof healthandsocialcare[eb/ol].[ ].htp://www. bgs.org.uk/com pendium/comd4.html. [8]Y,,,.2347 S RS 1 [J]. c,2015,30(2):87 90.DOI:10.387/ hlx [9] (Z,B[\,.]^,.234,-7 _` IS [J]."A,2014,20(10): DOI: /cma.j.isn [10] a,y%n,bc,.2 = G 4, - 7 F N[J]. c:,,2014,29(9): DOI: /hlx [11] J,,.V Y [ [J]. 3,2015,15(2): [12] Z, c(,,. 23, : ; [J]. " A,2013,19 (16): DOI: /cma.j.isn (@ : )

Microsoft Word - 2012FIC展会总结.doc

Microsoft Word - 2012FIC展会总结.doc 2012 年 3 月食品工业科技参展报道 ( 之三 ) 第十六届中国国际食品添加剂和配料展览会暨第二十二届全国食品添加剂生产应用技术展示会 ( 简称 :FIC) 举办时间 :2012 年 3 月 28-30 日举办地点 : 上海世博展览馆主办单位 : 中国食