Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. * 1349 *
153,370 156,933 82,684 39,044 35,898 41,371 34,050 18,462 641 (2,506) (1,057) (3,515) (1,586) (1,760) (1,356) 40,314 30,535 16,876 (1,119) (3,862) (5,034) (6,315) (2,686) 2,440 35,280 24,220 14,190 1,321 (3,862) 36,296 27,904 16,205 3,353 (2,301) (1,016) (3,684) (2,015) (2,032) (1,561) 35,280 24,220 14,201 1,316 (3,862) 36,296 27,904 16,212 3,348 (2,301) (1,016) (3,684) (2,011) (2,032) (1,561) 53,356 41,042 21,916 3,980 887 0.0393 0.0337 0.0228 0.0047 (0.0032) 748,575 749,216 537,296 358,881 304,154 (147,370) (183,291) (277,183) (157,814) (135,449) 601,205 565,925 260,113 201,067 168,705 569,013 532,717 223,228 170,062 139,243 32,192 33,208 36,885 31,005 29,462 601,205 565,925 260,113 201,067 168,705 1
153,370,000156,933,000 2% 25% 8% 150,870,00098%2% 154,355,000 ALA Doxorubicin liposome 49% 46% 20,000,000 2,500,0001.6% 2,500,000 2
78,000 12,190,00012,273,000 92% 41,371,00034,050,000 22% 25,668,00057% 16,333,000 12,069,000 9,554,000 5,223,000 7 28,852,00065% 17,524,000 3
82,757,00011% 93,179,000 60.4%54.9% 13,818,0007% 12,927,000 50,000 3,313,000 98% H 1,057,00070% 3,515,000 35,280,000 24,220,000 46% 36,296,000 27,904,000 30% 4
-Fc (rhtnfr(m):fc) 2014 5 I PCT (PTH) I (ALA) HPV I (ALA) II FDA FDA 5
I 2013 12 HPV 95% (GMP 2015 6
GMP FDA GMP 7
25,000,000 6.40% 25,000,000 25,000,000 284,202,000 0.76 1.01 259,202,000 284,927,000 342,003,000 280,998,000 8
470 426 28,907,000 23,770,000 142,000,000 0.10 H 1.70 233,909,000 185,575,000 2012 5 142013 1 16 20,000 3,619 10,000 511 20,000 4,247 CD30 (CD30-MMAE) 30,000 4,851 20,000 20,000 85,575 85,575 185,575 118,803 9
(a)xv 7 8 (b)352 (c) 57,886,430 9.93% 6.27% 22,312,860 3.83% 2.42% 19,260,710 3.30% 2.09% 10
XV 2 3 336 139,578,560 23.94% 22.77% H 70,564,000 20.75% 139,578,560 23.94% 22.77% H 70,564,000 20.75% 156,892,912 26.91% 17.00% 80,000,000 13.72% 8.67% 30,636,286 5.25% 3.32% 30,636,286 5.25% 3.32% Boxin China H 27,000,000 7.94% 2.93% Growth Fund I LP H 23,639,000 6.95% 2.56% 11
12
a) b) c) d) e) f) 2 3 13
54 600226 57,886,430 6.27% 50 22,312,860 2.42% 14
44 19,260,710 2.09% 46, 15
41, 57 Victoria Capital Limited IMD, 16
67 600637 601601 02601 59 8125 17
69 0656 40 18
31 50 870,000 0.09% 68 19
50 20 H.Lee.Moffitt 46 52 OTC 20
52 33 21
6 153,370 156,933 8 (12,190) (12,273) 141,180 144,660 7 25,668 16,333 8 (28,852) (17,524) 8 (82,757) (93,179) 8 (13,818) (12,927) 8 (50) (3,313) 41,371 34,050 (1,057) (3,515) 40,314 30,535 9 (5,034) (6,315) 35,280 24,220 35,280 24,220 36,296 27,904 (1,016) (3,684) 35,280 24,220 36,296 27,904 (1,016) (3,684) 35,280 24,220 11 0.0393 0.0337 27 40 10 22
12 32,945 33,340 12 278,037 264,732 12 2,128 2,099 12 13,900 9,997 5,408 6,383 13 2,643 2,954 335,061 319,505 24,347 15,568 14 80,034 66,986 17,080 20,432 7,851 1,798 284,202 324,927 413,514 429,711 748,575 749,216 23
17 25,000 15 31,646 35,647 31,646 60,647 16 5,632 8,843 56,961 68,159 3,526 8,977 17 25,000 15,000 15 24,605 21,665 115,724 122,644 147,370 183,291 92,300 92,300 476,713 440,417 569,013 532,717 32,192 33,208 601,205 565,925 748,575 749,216 297,790 307,067 632,851 626,572 27 40 24
10,824 (5,648) (1,057) (3,515) 481 840 (9,510) (6,723) 738 (15,046) (27,985) (26,690) (2,283) (819) (148) 405 2 (681,708) (336,000) 685,256 336,714 (26,463) (26,793) 207,857 (1,780) 15,000 (15,000) (61,498) (15,000) 159,579 (40,725) 117,740 324,927 158,267 284,202 276,007 27 40 25
71,000 211,240 6,419 (65,431) 36,885 260,113 27,904 (3,684) 24,220 27,904 (3,684) 24,220 17,750 186,416 204,166 17,750 186,416 204,166 88,750 397,656 6,419 (37,527) 33,201 488,499 92,300 412,211 16,168 12,038 33,208 565,925 36,296 (1,016) 35,280 36,296 (1,016) 35,280 92,300 412,211 16,168 48,334 32,192 601,205 27 40 26
1. 5,295,000 5,295,000 53,000,000 1.00 53,000,0000.10530,000,000 198,000,0000.10 H18,000,000 H 71,000,000 142,000,0000.10 H1.70 85,200,000 71,000,000 0.51 35,500,000 88,750,000 27
1. 0.51 35,500,000 92,300,000 H H 100% 65% 69.77% 56% 308 2. 34 28
3. (i) 10 12 27 32 36 39 21 (ii) 2 3 8 9 11 13 14 15 16 19 24 37 38 40 29
4. 5. 5.1 5.2 6. 150,870 154,355 (a) 2,500 2,500 (b) 78 153,370 156,933 30
6. (a) (b) 20,000,000 2,500,000 (r-tpa) 15,000,000 2007 2% 5%5 78,000 7. (a) 12,069 9,416 9,554 5,223 (b) 3,548 714 481 840 16 140 25,668 16,333 (a) (b) 6 80% 80% 31
8. 395 395 (342) 395 53 954 507 119 11 4,653 266 435 7,308 4,444 9,908 10,724 13,091 6,421 (2,574) 10,517 6,421 13 (11) 529 404 7,314 2,582 28,907 23,770 50,495 71,310 10,637 9,405 2,959 3,105 2,959 5,790 137,667 139,216 32
9. 15% 15% 15% 25%25% 4,059 6,015 975 300 5,034 6,315 10. 11. 36,296 27,904 ( 000) 923,000 827,287 0.0393 0.0337 33
12. 37,356 317,796 5,283 16,858 26,814 148 4,857 (605) 37,356 344,005 5,431 21,715 4,016 53,064 3,184 6,861 395 13,091 119 954 (187) 4,411 65,968 3,303 7,815 32,945 278,037 2,128 13,900 37,356 265,808 4,623 11,664 35,992 819 (1,218) 37,356 300,582 4,623 12,483 3,226 44,545 2,978 5,847 395 6,421 11 507 (948) 3,621 50,018 2,989 6,354 33,735 250,564 1,634 6,129 34
13. 2,643 2,954 14. (a) 79,634 64,832 (6,400) (1,756) 73,234 63,076 (b) 6,800 3,910 80,034 66,986 35
14. (a) 1 4 52,202 55,315 30 8,828 3,712 30 60 5,185 1,674 60 90 522 600 90 11,332 2,231 1,565 1,300 79,634 64,832 (b) 15. 49,822 40,962 3,333 5,833 7(a) 3,096 10,517 56,251 57,312 (24,605) (21,665) 31,646 35,647 36
16. (a) 5,632 8,843 (a) 30 4,317 7,924 31 60 129 551 61 90 424 4 90 762 201 163 5,632 8,843 37
17. (a) 25,000 25,000 15,000 (25,000) (15,000) 25,000 (a) 25,000 15,000 25,000 15,000 (a) 25,000,000 6.40% 1,057,0003,515,000 1 25,000 15,000 1 2 25,000 25,000 40,000 38
18. (i) 6,103 7,323 (ii) 4,648 3,203 1,798 7,851 1,798 3,096 10,517 39
19. 78,000 40