...1...2...3...21...22...22...22...24 1...24 2...25...27...32...35...36...65...80...81 1
Wistar 1. 2. 3. 1. 2. 3. 2
[1] 800 400 3 (Extracellularmatrix ECM) 3
Lysaght [2] 2001 3300 70 6 16 1990 35 20 50 [3] 20 80 1975 Rheinwaid [4] Green 4
[5 6] 1. Rheinwald Green 0.1 3T3 J2 10 15 37 5 10 CO 2 10 12d 1 2 3T3 1mm 2 15 14 d (in Vitro) (in vivo) - ECM 2. CO 2 5
Ca 2 ph Ca 2+ Bickenbach-JR [7] 1999 AlloDerm AlloDerm 1 6 12 1981 O 6
Conner [8] 2 1984 Gallico [9] 50 2 95 Teepe [10] 1990 17, 3 [10 11] 3 Tom [12] 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 1. Alloderm(Lifecell Woodlands Tex) 7
Heck [13] 1985 4 Cuono [14] 90 [15 20] Wainwright [21,22] 1995 1996 8
Lattari [23] Tsai 1999 [24] Alloderm [16] ReDerm ( HIV) [21,22] [25] [26] [27 28] [29] [30 31] [32,33,34,35] [36] [37,38,39 40 41] [42] Rennekampff 1997 [43] Matouskova [44] (Upside Down) (recombined human pig skin RHPS) 9
93 Gustafson [45] Dispase Triton X 100 2 Walden [46] 2000 Sheridan [47] 7 45.7 14.2 98 1 p<0.05 Lam 3T3 [48] 2.Integra (Integra Life Sciences Plainsboro N.J ) 6- ECM 1981 Bruke [49] Yannas 6-10
(0 009 ) Integra 2 3 Soejima 1997 Integra [50] [51] Michaeli, 2 4 3 [52] 5 10 11
4 8 Integra ( 2 6 ) [53] [54 56] Hansbrough 1989 - Integra 4 9 [57] Compton 1998-5000 /cm 2, 19 60 1 8 12 [58] Boyce - 12
1 4 [59] 3.Dermagraft (Advanced Tissue Sciences La JOlla Calif) FDA /Polyglactin PGA/PGL PGA/PGL Cooper1991 /Polyglactin PGA/PGL [60] Hansbrough 1992 Dermagraft 14 Dermagraft [61] Gentzkow 1996 Dermagraft [62] 1 / Jiang1998 Dermagrft / [63] Hans. O 1996 Dermagragt 13
integrin Dermagraft, Alloderm [78] Dermagraft-TC Transitional Covering TransCyte Dermagraft-TC Red Dermagraft-TC Blue Hansbrough1997 Dermagraft-TC Red Blue Dermagraft-Blue Dermagraft-Red 5 7 Dermagraft-TC [64] Hickerson [65] Dermagraft-TC Noordenbos 1999 14 Dermagraft 1 14
SD-Ag Dermagraft [66] 4. Apligraf (Organogenesis Canton Mass) 1998 FDA 2 3 ( [3] HIV ) [67 68 69] Apligraf 6 Waymack Apligraf Apligrf 24 [70] Apligraf Eaglstein 1999 15
Apligraf 73.3 2 4 56.6 53.6 [71] Kirsner Apligrf [72] Falabella Apligraf [73] 5.Hydroderm (Wilshire Medical Inc., Dallas, Texas) (polyurethane membranes, ) Wright [74] 1998 15 Hydroderm Hydroderm Rheinwald and Green Rennekampff Hydroderm [75] 16