B
-
(Immune Tolerance Phase) 3 (Immune Clearance Phase) 20-30 T B (Residue Phase) 40-50
B
B.C.D,,,,.
Hepatitis B :Average 60-90 days( 45-180 days) ( ) : <5 yrs <10% 5 yrs 30%-50% Acute case-fatality rate: 0.5%-1% : <5 yrs 30%-90% 5 yrs 2%-10%
How do you get hepatitis B? It is passed by contact with the blood or other body fluids of someone who has the virus.
How does my baby get hepatitis B from me? If you have hepatitis B and a tiny bit of your blood gets inside your baby at birth.
2005/4/15 2
B C
DNA (HBV DNA) ( viraemia) B B HBsAg B ( ) HBeAg B e ( )
2005/4/15 2
B α-ifn - *(16-24 ) Lamivudine - * ( 9-12 ) $$$ (Zefix 100mg, 3-TC)
(Lamivudine) (Zefix) 1998 FDA B,1999.10 2003.10 B (reverse transcriptase) (HBV RNA-dependent DNA polymerase) (HBeAg: + -) 16-35 27-50 33-65 GPT>200 64
B GPT 2 (>80) 5 (>200)
2005/4/15 3
B
B 1984 1989 1994 HBsAg(+) 9.8% 1.3% HBcAb(+) 26% 15% 4 % Anti-HBs(+) 79%
B B HBsAg(-) & anti-hbs(-) B vs 1 ------ 2 ------ 3 1 5
(Liver Cirrhosis)
(Liver Cirrhosis)