CSPC PHARMACEUTICAL GROUP LIMITED 1093 % % 6,582,194 4,773,634 37.9% 39.5% 4,792,219 4,193,217 14.3% 15.8% 1,215,084 1,333,565-8.9% -7.6% C 1,853,700 1,308,687 41.6% 43.1% 1,019,332 759,938 34.1% 36.2% 15,462,529 12,369,041 25.0% 26.6% 9,345,968 6,308,809 48.1% 49.8% 3,481,643 2,649,484 31.4% 33.2% 2,770,522 2,100,848 31.9% 33.6% 45.48 35.25 +29.0% 15.00 12.00 +25.0% 815,258 403,140 102.2% 1
27.71 31.9% 10.32 72.9% 2
( 3
C 4
2 15,462,529 12,369,041 (6,116,561) (6,060,232) 9,345,968 6,308,809 120,478 106,970 (4,374,637) (2,788,160) (682,011) (553,694) (928,155) (424,441) 3,481,643 2,649,484 (26,631) (41,711) 10,277 27,559 3 3,465,289 2,635,332 4 (685,245) (522,107) 2,780,044 2,113,225 816,415 (658,279) 6,780 (2,773) 3,177 826,372 (661,052) 3,606,416 1,452,173 5
2,770,522 2,100,848 9,522 12,377 2,780,044 2,113,225 3,591,527 1,445,017 14,889 7,156 3,606,416 1,452,173 5 45.48 35.25 5 45.48 35.00 6
6,662,523 5,415,032 573,080 526,712 121,736 111,785 103,176 79,232 109,978 80,089 316,742 91,732 20,721 27,986 7,907,956 6,332,568 2,900,781 1,933,147 7 2,334,279 1,835,266 8 1,477,001 1,215,156 69,536 73,570 276,830 115,986 18,263 16,419 732 521 1,315,789 3,480 2,875 5,238,033 3,234,678 13,634,724 8,427,618 9 4,513,383 2,937,893 10 59,809 100,559 9,319 43,419 657 206,685 147,769 927,282 897,777 5,759,897 4,084,655 7
7,874,827 4,342,963 15,782,783 10,675,531 131,602 68,865 59,809 240,380 183,976 174,964 375,387 484,209 15,407,396 10,191,322 12,922,199 10,569,620 2,400,174 (461,994) 15,322,373 10,107,626 85,023 83,696 15,407,396 10,191,322 8
1. 436 662(3) 6 3 406(2) 407(2) (3) 2. 15,462,529 12,369,041 8 (a) (b) (c) (d) C 9
C 11,374,413 1,215,084 1,853,700 1,019,332 15,462,529 15,462,529 93,437 39,624 8,060 141,121 (141,121) 11,374,413 1,308,521 1,893,324 1,027,392 15,603,650 (141,121) 15,462,529 2,724,406 45,336 614,164 200,109 3,584,015 3,584,015 25,148 (127,520) 3,481,643 (26,631) 10,277 3,465,289 C 8,966,851 1,333,565 1,308,687 759,938 12,369,041 12,369,041 72,689 12,621 7,688 92,998 (92,998) 8,966,851 1,406,254 1,321,308 767,626 12,462,039 (92,998) 12,369,041 2,554,555 24,493 25,726 175,254 2,780,028 2,780,028 13,005 (143,549) 2,649,484 (41,711) 27,559 2,635,332 10
12,340,123 9,679,224 1,264,272 1,228,182 851,288 659,305 862,902 654,555 143,944 147,775 15,462,529 12,369,041 11
3. 1,015,460 810,800 109,183 100,533 1,124,643 911,333 86,186 17,796 17,483 19,218 612,856 550,713 716,525 587,727 3,640 3,500 (34,353) (24,976) (25,148) (13,005) 19,947 20,572 36,938 (10,009) 815,258 403,140 38,543 32,791 12
4. 546,780 450,233 59,950 41,899 14,989 621,719 492,132 63,526 29,975 685,245 522,107 16.5% 25% 15% 35% 5.5% 35% 21% 13
5. 2,770,522 2,100,848 6,091,481 5,960,417 224 42,275 6,091,705 6,002,692 6. 12 11 726,482 650,212 15 12 14
7. 1,863,900 1,492,855 (13,491) (10,423) 1,850,409 1,482,432 202,499 150,585 50,733 51,720 92,827 46,891 137,811 103,638 2,334,279 1,835,266 90 90 0 90 1,590,027 1,357,953 91 180 238,594 114,647 181 365 21,788 9,832 1,850,409 1,482,432 8. 180 180 15
9. 1,485,365 1,113,908 909,486 547,937 159,531 86,518 60,169 79,299 985,234 678,108 138,679 126,114 188,388 109,749 443,697 115,388 142,834 80,872 4,513,383 2,937,893 0 90 1,098,644 1,008,024 91 180 232,799 45,290 180 153,922 60,594 1,485,365 1,113,908 90 90 10. 180 180 16
154.63 25.0% 26.6% 27.71 31.9% 33.6% 45.48 15 113.74 26.8% 28.4% 65.82 37.9% 39.5% (2014) 17
(2017) (2015) b B (2015) 18
21 110 10,000 5.0%4.6% p>0.05 1.1% 0.7% 2.8% 1.1% (NCCN) 19
1,537 20
C ANDA 47.92 14.3% 15.8% 21
C C 200 25 12 3 3 4 55 48 1. 2. 6 HA121-28 CSPCHA115 3. 11 4. 26 22
5. 20 1 9 DBPR108 SKLB1028 B 1. 8 ANDA 100 2. 5 ANDA 3. 3 80 DP303c ANDA 2 8 23
11,374,413 8,966,851 26.8% 4,088,116 3,402,190 20.2% 15,462,529 12,369,041 25.0% 3,481,643 2,649,484 31.4% 22.5% 21.4% 2,770,522 2,100,848 31.9% 17.9% 17.0% 45.48 35.25 29.0% 26.8% 113.74 65.82 37.9% 38.6% 42.6% C C 31.9% 27.71 32.88 29.16 41 40 116 173 2.4 2.1 13.20 24
65.57 32.38 9.87 11.38 55.70 21.00 9.78 0.09 9.27 0.6 11.2% 6.4% 94% 6% 11,206 (i) (ii) (iii) 14 A.2.1 A.2.1 25
183 183 26