SINO BIOPHARMACEUTICAL LIMITED : 1177 2017
1 1177 www.sinobiopharm.com FCCA,CPA 166 1
43 SMP Partners (Cayman) Limited Royal Bank House 3rd Floor, 24 Shedden Road P.O. Box 1586 Grand Cayman KY1-1110 Cayman Islands 183 22 Codan Trust Company (Cayman) Limited Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands 1 41 09 2 39 Conyers Dill & Pearman, Cayman Boundary Hall, 2nd Floor Cricket Square Hutchins Drive P.O. Box 2681 KY1-1111 Cayman Islands 1 C2 308A 1 22 18 1 24 01 2
748,286 10.6% 107,634110,058 22.9% 25.7% 14.52 14.8522.9% 25.7% 11.6% 385,964 2 1.53.5 3
+ 130 4
GMP PVC GMP GMP 5
GMP CN20110001 MSCI 50 http://www.sinobiopharm.com 6
6.9% 0.2 VEGFR PDGFR FGFR c-kit,12 17 46 27 1137 10 7
748,286 10.6% 107,634 110,058 22.9%25.7% 14.52 14.85 22.9%25.7% 385,964 332,839 44.5% 5,445 20,009 98,037 5.0% 8
17,692 161,976 7.0% 19,675 99.2% 5,681 64.1% 152,77516.7% 77,43010.3% 8,336 32,307 16.8% 29,210 10.8% 9
(DDS) GMP 58,487 16,857 20.1% 80,720 10.8% 14,084 16,733 13.3% 10,694 7,566 17.7% 8,619 17.7% 8,44735.3% 5,036 43.3% 10
91,22610.0% DDS 71,699 27.7% 17,468 43.4% 60,138 8.0% 41,731 19.1% 10,924 34.8% 45,409 6.1% 35,4547,509 45.4% 11
35,393 4.7% 25,072 9,882 33,238 4.4% 21,341 32.6% 8,588 31,208 4.2% 11,124 22.3% 16,536 6559.5% 12
5,516 0.7% 1 4,479 18.5% 53,097 36,945 282,559212,236 62,700 57,363 52,000 38,000 21,000 51,496 14.4% 13
(i) 16,02514,793Karolinska Development AB 272,858,2948%(ii) 70,374 40,856 6,772 2,424 199 11 45153 32187 2224133 115,55315.4% 17 74 71 2 1559 1356 14
385,964 376,579 99,882 136,947163,253 167,897 42,276 45,952 1,960,637 1,834,008,869,436 759,81744.3% 41.4% 16,821 601,134,000 548,394,000 15
16
3 7,482,859 6,768,203 (1,568,413) (1,452,802) 5,914,446 5,315,401 3 223,739 124,687 (3,169,426) (2,830,705) (254,581) (417,999) (1,173,558) (954,357) 4 (34,127) (27,862) 177,776 172,294 5 1,684,269 1,381,459 6 (285,637) (219,617) 1,398,632 1,161,842 1,100,582 875,596 298,050 286,246 8 1,398,632 1,161,842 14.85 11.81 7 17
1,398,632 1,161,842 (113,300) 108,491 (113,300) 108,491 1,285,332 1,270,333 988,528 983,602 296,804 286,731 1,285,332 1,270,333 18
2,866,296 2,658,160 397,442 421,494 519,927 465,061 99,384 99,384 177,243 176,203 1,017,212 946,660 530,972 369,447 160,246 147,926 245,522 260,817 360,671 40,013 6,374,915 5,585,165 873,899 917,868 9 2,399,646 1,995,827 2,568,941 3,195,323 349,199 2,825,588 2,122,358 703,742 408,557 10 3,859,639 3,765,786 13,231,455 12,754,918 11 1,165,229 826,734 96,293 193,024 4,641,820 3,271,494 998,823 1,369,474 6,902,165 5,660,726 6,329,290 7,094,192 12,704,205 12,679,357 19
133,986 201,603 1,632,527 1,678,968 25,683 56,875 1,792,196 1,937,446 10,912,009 10,741,911 12 170,033 170,033 8,474,044 7,813,402 8,644,077 7,983,435 2,267,932 2,758,476 10,912,009 10,741,911 20
170,033 1,128,455 (169,686) 185,993 22,691 1,420,955 (83,207) 5,213,051 95,150 7,983,435 2,758,476 10,741,911 1,100,582 1,100,582 298,050 1,398,632 (112,054) (112,054) (1,246) (113,300) (112,054) 1,100,582 988,528 296,804 1,285,332 698 698 (788,046) (788,046) (95,150) (95,150) (95,150) (232,736) (232,736) (232,736) 14,022 (14,022) 170,033 1,128,455 (169,686) 185,993 22,691 1,434,977 (195,261) 6,066,875 8,644,077 2,267,932 10,912,009 170,033 1,128,455 (169,686) 169,037 22,691 1,074,912 (325,396) 4,335,530 90,121 6,495,697 2,246,168 8,741,865 875,596 875,596 286,246 1,161,842 108,006 108,006 485 108,491 108,006 875,596 983,602 286,731 1,270,333 (546,228) (546,228) (90,121) (90,121) (90,121) (190,663) (190,663) (190,663) 170,033 1,128,455 (169,686) 169,037 22,691 1,074,912 (217,390) 5,020,463 7,198,515 1,986,671 9,185,186 21
3,218,565 1,440,863 (1,585,214) 251,039 (1,389,331) (802,576) 244,020 889,326 3,498,538 2,121,086 (154,594) 122,659 3,587,964 3,133,071 1,696,909 1,808,248 1,891,055 1,324,823 3,587,964 3,133,071 22
1. (a) (b) (c) 23
1. (i) (ii)(iii)(i) (ii)(iii) 2. (a) (b) (c) (i) (ii) 24
2. 7,266,830 1,935 214,094 7,482,859 1,496,927 96,615 37,261 1,630,803 22,302 177,776 (146,612) 1,684,269 (285,637) 1,398,632 13,146,270 4,585,784 611,582 18,343,636 1,017,212 245,522 19,606,370 5,560,958 2,712,396 299,031 8,572,385 121,976 8,694,361 144,116 15,125 9,200 168,441 436,967 69 437,036 527 37 564 25
2. 6,550,516 1,814 215,873 6,768,203 1,460,899 (125,838) 14,754 1,349,815 15,535 172,294 (156,185) 1,381,459 (219,617) 1,161,842 10,277,943 3,116,733 962,865 14,357,541 1,132,148 237,296 15,726,985 4,336,810 1,759,783 263,477 6,360,070 181,730 6,541,800 123,161 14,126 8,957 146,244 169,662 11 1,490 171,163 378 378 90% 90% 10% 26
3. 7,297,582 6,583,102 185,277 185,101 7,482,859 6,768,203 22,302 15,535 8,364 8,567 6,207 9,384 14,714 15,555 2,579 507 59,359 50,694 2,686 2,556 13,612 19,785 129,823 122,583 976 249 67,721 25,219 1,855 93,916 2,104 223,739 124,687 27
4. 34,127 27,862 5. 1,568,413 1,452,802 150,863 130,745 11,509 10,951 482 482 5,587 4,066 1,155,532 914,606 (976) (249) 564 378 (22,302) (15,535) (6,207) (9,384) (59,359) (50,694) (25,219) (1,855) 978 1,735 1,921 1,951 488,427 455,016 112,707 93,378 601,134 548,394 16,288 64 (70,165) 32,655 28
6. 299,058 246,820 (13,421) (27,203) 285,637 219,617 16.5%16.5% 15% 25% 7. 2 1.5 18322 8. 1,100,582,000 875,596,000 7,412,192,209 7,412,192,209 29
9. 60180 90 2,196,235 1,657,541 91180 161,569 314,366 180 41,842 23,920 2,399,646 1,995,827 10. 1,696,909 1,472,778 1,891,055 2,025,760 271,675 267,248 11. 3,859,639 3,765,786 90 962,253 573,680 91180 114,857 215,202 180 88,119 37,852 1,165,229 826,734 30
12. 7,412,192,2090.02294 7,412,192,209 0.02294 170,033 170,033 13. a 531 505 a 1,800 1,800 b 1,557 1,415 (a) (b) 31
571 XV78 352 (1) 140,400,000 1,082,126,722 1,222,526,722 16.49% (2) 63,371,000 1,800,000,000 1,863,371,000 25.14% 61,257,000 61,257,000 0.83% (1) Validated Profits Limited1,082,126,722 (2) Remarkable Industries Limited 1,050,000,000750,000,000 32
(1) 288,000,000 57.6% 229,250 0.18% 26,583 0.53% (1) 1 XV XV78 352 33
XV 23 336 Validated Profits Limited (1) 1,082,126,722 14.60% (2) 1,050,000,000 14.17% Remarkable Industries Limited (2) 750,000,000 10.11% (1) Validated Profits Limited (2) Remarkable Industries Limited XV23 336 34
494,146,14710% 1% (i)0.1% (ii)5 301 35
(i) (ii) (iii) 180 36
A.6.7 3.10 3.10(A) 13.18 300,000,000 37
38