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3 Mauffrey Benoit Jean Marie Mauffrey Benoit Jean Marie Mauffrey Benoit Jean Marie Mauffrey Benoit Jean Marie Mauffrey Benoit Jean Marie MBA, ACA, CPA (practising) Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY Cayman Islands Royal Bank of Canada Trust Company (Cayman) Limited 4th Floor, Royal Bank House 24 Shedden Road, George Town Grand Cayman KY Cayman Islands

4 % 654, , ,895 75, ,613 61, , , , , , , ,300 80,000 75, ,000 60,000 40, ,000 20,

5 4

6 Carisolv 10,000,000 5% 4 30% 5

7 ,000,000 6% 3 10% 4. 6

8 5. Elektron Technology UK LimitedElektron Elektron II8 Elektron Elektron Henson ,500,000Abpro CorporationAbproC Abpro rdna PDGF III Abpro Abpro 7

9 MSCIMSCI Global Small Cap Indexes China MSCI 654,000, % 75,300, ,900, % 43% 41% 16% 39 Carisolv

10 9

11 61 Essex Bio-Investment Limited KPMG DHL (Businessman of the Year)Chevalier DE L ORDRE NATIONAL DU MERITE (i)146,479,000 Dynatech Ventures Pte Ltd6,666,667 (ii) 500,000 Dynatech Ventures Pte Ltd Essex Investment (Singapore) Pte Ltd 50 Essex Bio-Investment Limited 4,738,300 3,500, Essex Bio-Investment Limited 2,869,150 1,168,000 10

12 61 XV Mauffrey Benoit Jean Marie 63Mauffrey Mauffrey XV 53The University of Southwestern Louisiana The University of New England 24 XV 52 11

13 12

14 1. Carisolv Carisolv 3 Carisolv CarisolvCarisolv Caritool 10,000,0005% 4 30%

15 3. 15,000,000 6% 3 10% 4. 7 CFDA 14

16 5. Elektron Technology UK LimitedElektron Elektron ElektronII Elektron8 II Elektron Elektron Henson 9000 Elektron 8 Henson 9000 Elektron 6. Abpro CorporationAbpro 10 Abpro Abpro616,197 C 3,500,00027,300,000AbproC Abpro Abpro 61,619 61,619 Abpro Abpro 2.08 Abpro 15

17 Abpro 654,000, ,300, % Carisolv 43% 41%50% 38%

18 3,2001, ,000 bfgf bfgf PDGF III AbproAbpro VEGFAbpro Abpro Blow-Fill-Seal bfgf 17

19 GMP GMP bfgf GMP 4,000 1,000 MSCI MSCI MSCI Global Small Cap Indexes China MSCI 654,000,000518,300, % 41% 41% 38% 38% 43% 8% 51% 50% 6% 56% 8% 6% 100% 100% 8% 38% 18

20 16% 12% 529,600, ,300, % 104,900,00075,300, % 352,100,000271,400, % 51,200,000 42,400, % 10,800,000 7,000,000 64,600,000 62,000, %16.4% 51,000,00050,500, % 39.2% 20,000, % 3.31% 2,100,000 19

21 111,900,000 51,000,000 64,600,000 62,000, % 29.7% 20,000,000 27,600,00010,500,000 20

22 ,400,000 45,800, (a) 5% (b)30,000,000 (c)

23

24 %654,000, ,300,000104,900, % 43% 41% 50% 38% % 26% % 41%

25 ,600,000 62,000, %16.4% 51,000,00050,500, % 39.2% 20,000, Carisolv Abpro Corporation 1 GMP GMP GMPGMP GMP GMP GMP GMPGMP GMP 24

26 DNA 25

27 6 7 26

28 1 2 3 ERP 4 3,2001, ,000 27

29 17 2,791,000 2,791, (a) (b) (1) (2) 2. (a) (b) (c)

30 3. (a) ,675,000 (b) 6.02% 4. 1% (a) 1.00 (b) 14 (c) 29

31 8. (a) (b) (c) , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,000 30

32 , , , , , , , , , ,000 8,000,000 2,332,000 5,668, ,300, ,000 1,940, ,300,000 99,000 2,201, ,300, ,300, ,300, ,300, ,300, ,300,000 11,500, ,000 11,041, ,250, ,250, ,250, ,250,000 2,500, ,500,000 22,000,000 2,791,000 19,209,

33 ,137,66813,988, % 21.25% 43.7% 36.6% 5% Mauffrey Benoit Jean Marie 32

34 G 33

35 500,001 1,000,0001,500,001 2,000, XV ,645,667 (1) 27.46% 8,238,300 (2) 1.47% 4,037,150 (3) 0.72% 34

36 1. (a) 146,479,000 (b) 6,666,667Dynatech Ventures Pte LtdDynatech Dynatech Dynatech (c) 500, (i)4,738,300 (ii) 3,500, (i)2,869,150 (ii) 1,168,000 XV352 35

37 XV ,720,667 ( 1) 27.12% 153,645,667 ( 2) 27.46% 1. (a) 144,554,000 (b) 6,666,667DynatechDynatech Dynatech (c) 500, ,645, ,

38 41 14A

39 14 14 Mauffrey Benoit Jean Marie 38

40 3.13 4/4 1/1 4/4 1/1 4/4 1/1 4/4 1/1 Mauffrey Benoit Jean Marie 4/4 1/1 4/4 1/1 39

41 Mauffrey Benoit Jean Marie Mauffrey Benoit Jean Marie 40

42 1/1 1/1 1/1 Mauffrey Benoit Jean Marie 1/1 Mauffrey Benoit Jean Marie 41

43 1/1 1/1 1/1 Mauffrey Benoit Jean Marie 1/1 Mauffrey Benoit Jean Marie 42

44 4 4/4 Mauffrey Benoit Jean Marie 4/4 4/4 Mauffrey Benoit Jean Marie 1/1 1/1 1/1 Mauffrey Benoit Jean Marie 1/1 43

45 ,242 54,

46 13.51(2) (852) (i)(ii) (iii) (iv) 45

47

48 P

49 7 654,010, ,299,695 (124,418,858) (107,042,880) 529,591, ,256, ,382,673 2,039,556 (352,109,409) (271,365,907) (51,157,864) (42,368,241) 9 (2,056,200) (3,807,592) ,650,841 95,754, (25,755,651) (20,481,540) 104,895,190 75,273,091 (21,827,038) (790,435) 83,068,152 74,482, ,895,190 75,273,091 83,068,152 74,482,

50 17 174,335, ,934, ,774,816 7,342, ,416,690 2,588, ,367,867 26,099, ,937, ,882, ,398, ,000, ,113, ,964, ,678,761 35,220, ,427, ,557, ,746,406 25,624, ,700, ,613,176 61,974, ,465, ,076, ,578, ,041, ,288, ,592, ,000,000 50,549,728 2,940, , ,229, ,478, ,236, ,598, ,349, ,563, ,402,758 11,517, ,632, ,996, ,946, ,045, ,954,100 55,675, ,992, ,370, ,946, ,045,832 49

51 31 32(a) 32(b) 32(c) 33 55,675, , ,442 31,344,896 20,592,365 3,075, ,973, ,994,014 75,273,091 75,273,091 (790,435) (790,435) (790,435) 75,273,091 74,482,656 (10,021,500) (10,021,500) 12,590,662 12,590,662 10,171,990 (10,171,990) 55,675, , ,442 41,516,886 19,801,930 15,666, ,053, ,045, ,895, ,895,190 (21,827,038) (21,827,038) (21,827,038) 104,895,190 83,068,152 (12,248,500) (12,248,500) 279,100 6,140,200 6,419,300 2,798,156 (2,798,156) 4,662,052 4,662,052 55,954,100 9,908, ,442 41,516,886 (2,025,108) 17,530, ,699, ,946,836 50

52 130,650,841 95,754,631 8 (278,491) (206,279) 9 2,056,200 3,807, , , , , ,793,104 9,571, ,028, , ,662,052 12,590, ,925, ,281, , ,411, , ,946, ,394,113 (9,108,560) (29,370,804) (58,983,560) (50,261,450) (50,913,034) (23,188,913) 52,625,764 31,819,574 89,566,916 52,392,520 (2,056,200) (3,807,592) (18,870,251) (13,662,437) 68,640,465 34,922,491 51

53 (11,384,774) (7,519,886) (11,644,249) (9,921,579) (12,428,536) (3,882,008) 278, ,279 (20,000,000) 774,220 (58,286,856) (17,235,186) 51,000,000 37,869,225 (49,714,144) (37,869,225) 6,419,300 (12,248,500) (10,021,500) (4,543,344) (10,021,500) 5,810,265 7,665,805 61,974,415 54,526,652 (3,171,504) (218,042) 24 64,613,176 61,974, ,613,176 61,974,415 20,000,000 64,613,176 61,974,415 52

54 Cricket Square, Hutchins Drive, P.O. Box 2681, Grand Cayman KY1-1111, Cayman Islands (a)

55 2. (b)

56 2. (b)

57 2. (b) (c)

58 3. (a) (b) 4 (c) 4. (a) (b) 57

59 4. (c) (d) 58

60 4. (d) (e) 5% 18% 9% 19% 18% 20% 18% 59

61 4. (f) (g) (h) (i) (ii) (1) (2) (3) (4) (5) (6) 60

62 4. (h) (ii) (iii) 4(o) (i) (i) 61

63 4. (i) (i) (ii) 62

64 4. (i) (ii) (iii) (iv) 63

65 4. (i) (v) (vi) 39 (j) (k) (l) 64

66 4. (l) (m) 65

67 4. (m) (n) (o) 66

68 4. (o) 4(d) (p) (q) 67

69 4. (r) (s) (i) (1) (2) (3) (ii) (1) (2) (3) (4) (5) (6) (a) (7) (a)(i) (8) 68

70 4. (s) (iii) (1) (2) (3) (t) 5. (a) (i) 30% 69

71 5. (b) (i) (ii) (iii) 70

72 5. (b) (iv) (v) (vi) (vii) 71

73 5. (b) (viii) 4(h)(ii) 4(h)(ii) (ix) 21 72

74 6. (a) 602,836,400 51,174, ,010, ,940,812 30,446, ,387, ,593,327 29,706, ,299, ,434,661 8,137, ,571,981 73

75 6. (a) 152,387, ,571,981 (15,018,401) (9,419,096) (4,662,052) (12,590,662) (2,056,200) (3,807,592) 130,650,841 95,754,631 (b) (c) 138,995,561105,892, %20.4% ,836, ,593,327 51,174,099 29,706, ,010, ,299,695 74

76 8. 5,979,990 1,811, , , ,192 21,423 6,382,673 2,039, ,056,200 3,807, , , , , , , ,691,441 85,473,832 9,793,104 9,571,934 52,509,384 39,512,053 3,114,485 1,773,889 (1) 2,499,725 7,378,869 (1) 600, ,000 2,028, ,844 1,925,910 1,281, ,673 3,411, ,143 10,781,763 7,033,074 (1) 600,000600,0002,499,7257,378,869 1,562,3274,611,

77 11. (1) Mauffrey Benoit Jean Marie 180, , , , , , ,684 1,926,351 23,907 17,306 41,213 (2) 742, , ,000 2,300,000 (3) 729, , ,155 1,562,327 2,116,397 1,973,655 1,739, , , ,000 6,339, , , , , , , ,000 1,943,654 27,470 16,750 44,220 (2) 659, , ,000 2,000,000 (3) 2,152,170 2,152, ,453 4,611,793 3,469,794 3,307,420 1,822, , , ,000 9,109,667 (1) (2) (3) 4(p)33 76

78 ,040,927 1,765,946 33,635 31, ,735 2,644,095 2,970,297 4,441, ,001 1,000, ,500,001 2,000, ,000,001 2,500, ,001 1,000,0001,500,001 2,000, ,155,698 1,818,109 77

79 14. 20,228,846 12,616, ,526,805 7,864,597 25,755,651 20,481,540 15% 25% 130,650,841 95,754, %16.5% 21,557,389 15,799,514 (2,452,445) (1,441,607) 3,399,924 3,665,645 (108) (291,683) (1,687,356) (1,637,061) 965,844 (50,182) 3,972,403 4,436,914 25,755,651 20,481,540 78

80 ,988,525 12,248, ,541, ,750, ,895,190 75,273, ,541, ,750,000 7,169,680 2,216, ,710, ,966,050 79

81 ,424,202 61,604,733 4,104,976 3,677, ,811,661 5,905,274 1,239, , ,946 7,619,237 (4,524,484) (4,524,484) (399,549) (263,289) (14,682) (15,585) (693,105) 127,405,443 62,581,089 4,373,666 3,853, ,213,309 10,286,521 1,098,253 11,384,774 (7,056,957) (3,872,802) (248,990) (213,423) (11,392,172) 120,348,486 68,994,808 5,222,929 3,639, ,205,911 4,406,473 2,090,136 1,384,249 2,243,711 10,124,569 2,489,710 6,108, , ,034 9,571,934 (4,524,484) (4,524,484) 120,842 (2,032) (3,050) (9,213) 106,547 2,492,541 8,196,753 1,977,740 2,611,532 15,278,566 2,498,581 6,288, , ,194 9,793,104 (236,788) (702,481) (102,886) (159,439) (1,201,594) 4,754,334 13,782,466 2,506,989 2,826,287 23,870, ,594,152 55,212,342 2,715, , ,335, ,912,902 54,384,336 2,395,926 1,241, ,934, ,912,

82 18. 8,528,779 (36,646) 8,492,133 (470,377) 8,021, , ,894 (3,301) 979, ,276 (60,888) 1,086,316 6,935,440 (160,624) 6,774,816 7,512,205 (170,042) 7,342,

83 19. 2,602,414 (13,423) 2,588,991 (172,301) 2,416,690 (a) (b) 46%77% 10.9%14.3% 3%3% 82

84 20. 30,852,897 1,269,198 32,122,095 9,921,579 1,262,307 11,183,886 (121,282) (5,454) (126,736) 40,653,194 2,526,051 43,179,245 11,644,249 11,644,249 (2,711,869) (69,999) (2,781,868) 49,585,574 2,456,052 52,041,626 15,674, ,986 16,224, , , , ,673 (67,350) (2,746) (70,096) 15,607,296 1,472,932 17,080, , ,571 1,281,571 1,281,571 (915,122) (21,489) (936,611) 15,973,745 1,700,014 17,673,759 33,611, ,038 34,367,867 25,045,898 1,053,119 26,099, ,673 1,281,571 83

85 21. 10,000,000 11,937,4485% 100% 6,621,379 5,316,069 11,937, % % 3 84

86 21. 30% 30% 22. 3,882,008 B 23. 2,934, , ,909 23,874,896 38,592,872 21,169,601 7,312,525 4,044,729 73,145,066 25,624,239 (49,746,406) (25,624,239) 23,398,660 85

87 24. 54,000,000 57,500, % 25. 7,361,707 7,677,025 5,270,801 4,878,658 26,046,253 22,664,821 38,678,761 35,220, ,524, ,392,561 4,903, , ,427, ,557,

88 ,055,778 94,829, ,039,273 27,908, ,429,140 35,655, ,524, ,392, ,095, ,737,452 53,429,140 35,655, ,524, ,392, ,500,220 4,500,220 1,079,910 1,079,910 5,580,130 5,580,130 (774,220) (4,805,910) (2,880,000) 2,700, ,000 4,500,220 87

89 27. 20% 50% 65% 100, ,220 1,925, ,332,915 1,155,654 54,356,344 35,572,583 95,041,276 70,608,936 2,557,945 2,254, ,288, ,592,046 88

90 ,232, , , , ,706 2,332,915 1,155, ,000,000 50,549,728 20,000,000 51,000,000 50,549,728 51,000,000 50,549,728 20,000, % 3.31% % 7.8% 111,937,44875,825,000 51,000,000 50,549,728 89

91 30. (1,950,030) 2,276,738 4,434,126 4,760,834 (1,110,547) (1,110,547) 1,939,446 1,488,237 4,436,914 7,864,597 10,584 (8,090) 2,494 3,756,885 7,760,493 11,517,378 (1,371,913) (1,371,913) 1,554,402 3,972,403 5,526,805 (269,512) (269,512) 5,041,775 10,360,983 15,402,758 5% 90,700,00073,000,00091,500,000 72,500, ,000,000, ,000,000 1,000,000, ,000, ,750,000 55,675, ,750,000 55,675,000 2,791, , ,541,000 55,954, ,750,000 55,675,000 90

92 ,871 3,075,944 (1,823,757) 2,222,058 2,953,870 2,953, ,590,662 12,590,662 (10,021,500) (10,021,500) 969,871 15,666,606 (8,891,387) 7,745,090 11,277,555 11,277, ,662,052 4,662,052 6,140,200 6,140,200 2,798,156 (2,798,156) (12,248,500) (12,248,500) 9,908,227 17,530,502 (9,862,332) 17,576,397 (a) (b) (c) 10% 4(m) 91

93 33. (a) (i) (ii) (iii) 30% 1 (i) (ii) (iii) (i) (ii) 0.1% 5,000,000 92

94 33. (a) 19,500,000 (i) (ii) % 20% 20% 20% 20% (iii) , , , ,500,000 3,500,000 3,500, ,500,000 3,500,000 (2,332,000) 1,168, ,000,000 12,000,000 (459,000) 11,541,000 19,500,000 19,500,000 (2,791,000) 16,709,000 93

95 33. (a) 19,500, ,500, (2,791,000) ,709, ,500, ,709, ,500, ,900,000 11,700,000 4,062,05211,990,662 (b) 2,500,000 (1)

96 33. (b) (i) (1) 50% (2) 50% (ii) 1,800, ,000600, ,020 1,016, , ,020 1,129, ,170 2,080,770 1,016,190 95

97 35. 70,695,408 65,901,129 70,695,408 65,901, , , ,354 5,983, ,162 6,793, ,516 77,489,037 66,284,645 3,958,540 2,864,555 3,958,540 2,864,555 2,835,089 (2,481,039) 73,530,497 63,420, ,954,100 55,675, ,576,397 7,745,090 73,530,497 63,420,090 96

98 36. Essex Bio-Investment Limited 5 100% 8,000, % (1) 50,000, % 3,000, % (1) 25,000, % (1) 37. 2,569,615 (1) 25,068,640 2,792,872 7,756,000 27,638,255 10,548,872 (1) 97

99 38. (a) 24%23%37%40% 26 (b) 98

100 38. (b) 154,288, ,288, ,288,480 51,000,000 51,000,000 51,000, ,288, ,288, ,288, ,592, ,592, ,592,046 50,549,728 50,549,728 50,549, ,141, ,141, ,141,774 51,000,000 32,013,985 21,223,315 53,237,300 50,549,728 53,869,582 53,869,582 99

101 38. (c) , (d)

102 39. 51,000,000 50,549,728 (64,613,176) (61,974,415) (20,000,000) (33,613,176) (11,424,687) 412,946, ,045, (i) 3,882,008 5,316, ,661, ,232, ,859, ,232, ,288, ,141,

103 43. (a) 15,000,000 6% (b) Abpro CorporationAbpro Abpro Abpro Abpro616,197 C 3,500,00027,300,000AbproC AbproAbpro 61,61961,619 Abpro Abpro

104 ,010, ,299, ,046, ,255, ,716,340 (124,418,858) (107,042,880) (36,114,212) (23,563,134) (20,277,655) 529,591, ,256, ,932, ,692, ,438,685 6,382,673 2,039,556 1,751,491 2,427,379 1,126,117 (352,109,409) (271,365,907) (212,001,745) (168,012,021) (133,552,801) (51,157,864) (42,368,241) (25,573,935) (26,754,610) (19,884,567) (2,056,200) (3,807,592) (2,046,527) (1,701,743) 130,650,841 95,754,631 73,062,059 49,651,038 40,127,434 (25,755,651) (20,481,540) (18,165,363) (10,655,902) (6,924,806) 104,895,190 75,273,091 54,896,696 38,995,136 33,202,628 (21,827,038) (790,435) 5,315, ,797 3,307,433 83,068,152 74,482,656 60,212,668 39,692,933 36,510,061 83,068,152 74,482,656 60,212,668 39,692,933 36,510,

105 277,113, ,964, ,731, ,061,753 78,430, ,465, ,076, ,279, ,681, ,468,553 (208,229,323) (160,478,657) (128,256,757) (131,348,682) (53,557,989) 151,236, ,598,296 47,023,211 27,332,704 85,910,564 (15,402,758) (11,517,378) (4,760,834) (4,121,555) (1,080,000) 412,946, ,045, ,994, ,272, ,260,

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