China NT Pharma Group Company Limited 357,032, ,479,000 86,553,000 35,703, ,328, ,775,500 86,553, % 0.003% 0.005%
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- 悠 吉
- 7 years ago
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1 China NT Pharma Group Company Limited 中國泰凌醫藥集團有限公司 ( 於開曼群島註冊成立之有限公司 ) 股份代號 : 1011 全球發售 獨家全球協調人及獨家保薦人 聯席賬簿管理人及聯席牽頭經辦人
2 China NT Pharma Group Company Limited 357,032, ,479,000 86,553,000 35,703, ,328, ,775,500 86,553, % 0.003% 0.005% C (i) 144A (ii) S
3 (1) (3) (6)
4 (1)... (1) (2) 8 8. (3) 3. (4) (5) (6) (7) (8)
5 i iii
6 I-1... II-1... III-1... IV-1 TPG... V-1 TPG... VI-1... VII-1... VIII-1... IX-1
7 %23.4%6.9% 10.7% 1 8.7% 1 II 64% 54% II 79% 72% 3 1 Frost & Sullivan II II II II 2 Frost & Sullivan 3 Frost & Sullivan
8 2 26,5003, % 4 1,250 20% HIB 73% II27% 4
9 (37.1%) II A+C 57.1% 34.9%28.0% 47.6% MENET 5 5 MENET
10 42.9% 65.1% 53.8% 86.3% IMS70 15 I II II II 64% I 20.7% II 24.4% 31.3%39.3% , % II 15.2% 74 6 Frost & SullivanII II
11 Frost & SullivanII 7.6% 1,414.02, , % % % % 2.4%
12 643.5 a % b. 41 c. d. e. 15.9% 1, %
13 A+C Meningococcal ACYW 19.7% 13.9% 18.5%
14 34.2% 61.4% 38.2% 64.7%42.9% 66.5%II I 3.0% 5.1% 1.8%0.6% 0.9% 0.4% % 28% 15.8%50.3% 1.6%5.2% 29% 28%
15 58.2% 43.2% 47.5% TPG TPG NT Holdings TPGANT Holdings TPG TPG20.32% NT Holdings Golden Base TPG 250 TPG
16 Golden Base Golden BaseTPG
17 (i) (ii) (iii) (iv)
18 I
19
20 II II
21 ... 1,413,985 2,395,038 2,667, (1,178,904) (1,915,167) (2,004,775) (1) , , , ,196 7,670 28, (44,311) (1,739) 8, (108,129) (237,418) (354,456)... (43,147) (55,999) (90,056) (1)... 87, , , (14,277) (17,128) (45,379)... 73, , , (20,150) (58,087) (80,748)... 53, , , , , , (2)(3)... 53, , ,410 (1) 7.9 (2) 12.3 (3)
22 , , , , , , ,514 1,213,754 1,738, ,262 55,990 47, , , , ,269 1,713,000 2,467, ,066 1,947,188 2,755, ,005 2, ,005 2, ,188 1,042,657 1,358, , , , ,000 6, ,823 54,931 51, ,508 1,608,307 2,250, ,390 1,610,312 2,253, , , , , , , ,130 15,130 15, , , ,277
23 1, % % % 10%
24 20% % %
25
26 ,081,916, = (1)... 4,912 6,491 (2) (3) (1) 1,081,916,500 (2) ,081,916,500 (3) 1,081,916,
27 NT Holdings Business Monitor International
28 Golden Base Frost & Sullivan Frost & Sullivan Golden Base Golden Base Investment Limited
29 35,703,500 Golden Base IMS IMS Health Incorporated 321,328, ,775,500 86,553,000
30 MENET 270,479,000 NT BVI NT Pharma (Group) Co., Ltd NT Holdings NT Pharma (Holdings) Company Limited
31 53,554,000 15% Wyeth Inc. 144A S S 144A 144A
32 86,553,000 12,982,500 TPG Biotech TPG Star A NT Holdings SmithKline Beecham Glaxo Wellcome 80% TPG TPG Biotech TPG Star TPG Biotech TPG Biotech III Jaguar Ltd.
33 TPG Star TPG Star Jaguar Ltd.
34
35 GMP
36 GSP ISO9001 PEG A+C A+C
37 Meningococcal ACYW PEG
38 - - I II AB
39
40
41 , , % 57.0% 56.9% % % 20.4%9.5% 13.5% % % 2.4% %
42 A+C Meningococcal ACYW 19.7% 13.9% 18.5% SmithKline Beecham
43 63.4% 65.6% 60.7% 44.1% 46.6% 46.5% 85.0% 86.5% 82.3%
44 20.1% 4.8%
45 II I 3.0% 5.1% 1.8% 0.6% 0.9% 0.4% % 28%15.8% 50.3%1.6% 5.2%
46 19.0% 26.2% 30.5%
47 28.1
48 (2-8 C) %
49
50 1 1 Frost & Sullivan II II II II
51 1, ,395.02, %
52
53 24% 25% , % 27.6%
54 137.9
55
56 74 II
57 I IIII II III II I
58
59
60 0.5% 20% 1% 1%
61 (H1N1) (H1N1) (H1N1)
62 25% (i) (ii) (iii) (iv) 25% 10% 10%
63 10% 50%
64 46.68%
65
66 1. 14A (1)(b)1A 27 I 10(d) 17.02(1)(b) 1A 27 I342(1)(b) 10 (i) (ii)
67 17.02(1)(b)1A 27 (i) D. 10(d) 17.02(1)(b)1A 27 (ii) (i) (1) (2) (3)(4) (iii) (iv) D. (v) 17.02(1)(b)1A 27 I10 (vi) 342AI10(d) (i) D. 10(d)
68 (ii) (i) (1) (2) (3)(4) (iii) I10
69
70 (i) (ii) 44B(1) Codan Trust Company (Cayman) Limited
71
72 A E A PMB West University Avenue E1 Paso Texas US C A A 3 A1
73
74 Conyers Dill & Pearman Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY Cayman Islands
75 XI Cricket Square Hutchins Drive PO Box 2681 Grand Cayman KY Cayman Islands CPA FCCA A E
76 Codan Trust Company (Cayman) Limited Cricket Square, Hutchins Drive P.O. Box 2681 Grand Cayman, KY Cayman Islands
77 Frost & Sullivan Frost & Sullivan Frost & Sullivan Frost & Sullivan Frost & Sullivan Frost & Sullivan Frost & Sullivan Frost & Sullivan 11,75919, % GDP16.5% GDP
78 16,456 29, % GDP % % Euromonitor International
79 Euromonitor International 1,94713,240Euromonitor International 22,972156,210 5,026 11, % Euromonitor International 123Euromonitor International %
80 %... 2, , , % , , % , , % , , % , , % , , % % , , % , , % Euromonitor International Euromonitor International GDP 8% 11% Euromonitor International GDP4.1% (16.3%) (10.9%) GDP GDP Euromonitor International
81 ( ) 90% 65
82 % I II III
83
84 Frost & Sullivan Frost & Sullivan Frost & Sullivan Frost & Sullivan % ,600
85 Frost & Sullivan 2% 3%27% Frost & SullivanII % H1N1 I IIIIII I II I III I II 33%
86 III I II % 24.4% Frost & Sullivan II
87 Frost & Sullivan 3,534 28,407 II Frost & Sullivan 41 II II33%Frost & SullivanII Frost & Sullivan % (%) Frost & Sullivan
88 II II Frost & Sullivan II 74 Frost & Sullivan II 7.6% Frost & Sullivan Frost & SullivanZuellig Pharma Asia Pacific Frost & Sullivan 18.0%23.4%6.9%
89 10.7% 1 Frost & Sullivan Frost & Sullivan 1 II II
90 Frost & Sullivan % Frost & Sullivan % (%) (%) Frost & Sullivan Frost & Sullivan Frost & Sullivan 4% Frost & Sullivan
91 Frost & Sullivan 0.4% 8.7% Frost & Sullivan 2 4.7% Frost & Sullivan II % Frost & Sullivan 37.1% Frost & Sullivan % Frost & Sullivan A C 21% 27.9Frost & Sullivan 68.1% 91.9 Frost & Sullivan 2,000 Frost & Sullivan % 300 Frost & Sullivan % 2 II II
92 Business Monitor International 4683, % 15.3% Business Monitor International Business Monitor International 2, % Business Monitor International 1, % %
93 Business Monitor International 2, % % Business Monitor International 26.9%15.6% MENET 23.5% 17.4% 13.4% MENET IMS %
94 IMS 20 Frost & Sullivan
95 IMS Frost & Sullivan Frost & Sullivan Frost & Sullivan52,000 Frost & Sullivan Frost & Sullivan351,800 Frost & Sullivan Frost & SullivanFrost & Sullivan Frost & Sullivan Frost & Sullivan Frost & Sullivan
96 (a) (b) (c)
97 (d) (e) (f) (g) (h) (i)
98 GSP GSP GSP III I II II I II II II II II
99
100
101
102
103
104 80%
105
106
107 25%
108 10% 15% 18% 20% 22% 24% 25%24% 25% 17.0% *3%
109 3.0% 20.0%
110 SmithKline Beecham 80% 48 20,500 TPGTPG Biotech TPG StarNT Holdings NT Holdings 9.11% 18.21%ATPG 11 ISO9001
111 Smithkline Beecham Smithkline Beecham , ,000
112 TPG NT Holdings TPG NT Holdings TPG A+C TPG
113 TPG TPGNT Holdings NT Holdings TPG NT Holdings Golden Base TPG TPG Biotech TPG Star A NT Holdings 9.11% 18.21% TPG Biotech TPG Star 8,333,333 16,666,667A TPG Biotech TPG Star5 10 TPG3,333,333 6,666,667 TPG NT HoldingsNT Holdings TPG TPGANT Holdings A NT HoldingsNT Holdings NT Holdings TPG A A TPGA TPG Biotech TPG Star A A TPG Biotech TPG StarNT Holdings1,3632,726 A NT Holdings 12% 24%
114 TPG NT Holdings ANT Holdings TPG TPGNT Holdings NT HoldingsNT Holdings , A 125, AGolden Base908,500,000 TPG Biotech170,375,000 A TPG Star340,750,000 A NT Holdings TPG Biotech TPG Star TPG NT Holdings101,625,000 ATPG NT Holdings10 101,625,000 A NT Holdings ,625,000 NT Holdings Golden Base101,625,000
115 NT Holdings NT Holdings Golden Base... 1,010,125, % TPG Biotech ,249, % A TPG Star ,500, % A Golden Base TPG Biotech TPG Star Golden Base TPG A TPG TPGA TPG TPG NT HoldingsTPG TPG TPG TPGNT Holdings TPG Biotechnology Partners III L.P. TPG BiotechTPG Star L.P. TPG Star ANT Holdings ANT Holdings ANT Holdings TPGA
116 TPG NT HoldingsA TPG TPG NT Holdings TPG 30NT Holdings TPG Star TPG Biotech NT HoldingsTPG Star TPG Biotech ANT Holdings TPG NT Holdings TPG NT Holdings TPG TPG 37.8% 30 TPG TPG Golden Base ,062, % TPG Biotech... 73,273, % TPG Star ,549, % ,032, %
117 TPG TPG TPG TPG TPG NT Holdings TPG TPG TPG TPG TPGA Golden Base Golden Base NT Holdings 250 TPGANT Holdings 250Golden Base Golden Base TPGTPG Golden Base TPG TPG 15% TPG 20.32% TPG Golden Base TPG 35.32%TPG Golden Base TPG Golden Base TPG
118 TPG Golden Base TPG TPG TPG Star TPG BiotechTPGTPG 480 TPG TPG NT Holdings NT Holdings NT Holdings90,614,362 90,614, % NT Holdings 64 89,914,35789,914,357 NT Holdings 45,307,181 45,307, % 70% NT Holdings
119 % 3. Tai Ling Pharma Company Limited NT Holdings 626,250,000, NT Holdings (a) Tai Ning Pharmaceutical (Investment) Company Limited Goldwise Resources Limited NTP (China) Investment Co., Limited NT Pharma (HK) Limited NT BVI NT Holdings 451.3NT BVI NT Holdings 21.4 NT BVI
120 NT Holdings NT BVI NT Holdings9 1 (b) (c) NT Holdings NT BVINT Holdings 811,437, ,437,500NT Holdings NT Holdings Golden Base TPG Biotech TPG StarGolden Base TPG Biotech TPG Star NT Holdings Golden Base ,062, % TPG Biotech ,124, % TPG Star ,250, %
121 %
122 %23.4%6.9% 10.7% 1 8.7% 1 II 64% 54% II 79% 72% ,5003, % 4 1,250 20% 4 1 Frost & Sullivan II II II II 2 Frost & Sullivan 3 Frost & Sullivan 4
123 HIB 73% II27% (37.1%) II A+C 57.1% 34.9% 28.0% 47.6%
124 MENET % 65.1% 53.8% 86.3% IMS MENET
125 I II II II64% I 20.7% II 24.4% 31.3%39.3% , % II 15.2% 6 Frost & Sullivan
126 74 Frost & SullivanII 7.6% 1,414.02, ,668.0 %... 1,413,985 2,395,038 2,667, ,334 1,230,340 1,167, , , , , , , , , , , , , ,626 47,100 44, ,771 60,216 64, , , , ,862 13,119 10,255 (10.7) 1
127 II 12.9% 8,500 I 6 14 III I 20.7% II 24.4% II 64% II IMS 20 10
128 IMS70 15 Frost & Sullivan 0.4% 8.7% 7 Frost & Sullivan II 18.0% 23.4% % II15.2% 4.0% 10.7% 16.6% 24.9% % 7 Frost & Sullivan II II 8 Frost & Sullivan II II
129 % 2,80020,500 90% 3804, (Jiangsu Pharmaceutical Quality Control Society) % II37.1% 9 Frost & Sullivan
130 II54% II 22%480 A+C 90 II ACYW4 II 34.9% 850
131 26,5003, %1, % % 29.0% 19.7% (1) (1) (1) % 35.7% 31.4% (1) (1) (1) % 24.3% 12.9% (1) (1) (2) % 12.4% 8.1% (2) (3) (4) MENET 10 11
132 % 15 75% 60%
133 21,000 73% 4,20038,000
134 85% 20510
135 20
136 12 II 54% % % % , ,230, ,167, , , , , ,479, ,524, % 43.8% Frost & Sullivan 23.4% % 10.7% II64% % II 12 Frost & Sullivan II II II II 13 IIII
137 27% 48
138 % 40.0% 37.9% % 23.4% 27.5% % 22.6% 20.2% % 9.7% 9.5% % 4.3% 4.9% % 100% 100% 50
139 A+C AC
140 (i) (ii) (iii) (iv)
141 I II 15 II B 6 II B 6 II 3 5 II II 1 19 II 8 II I 24 3 II 6 3 II 3 II AC 3 5 II MF59-65 II 6 II I
142 I II II PCECV II I III 50.2% 37.9% 31.2%
143 100 20%
144 19 (Jiangsu Quality Control Society) 48 24
145 7,778 12,972 28,500
146 2, %II 87% 1 5% % % 2.4% 14
147 542109
148 , ,053, ,107, , , , , , , , , ,
149 8.7% 16 20,500 II (1) 131 (2) 16 Frost & Sullivan II II
150 % % %... 89, , ,
151 , %
152
153
154 II 0 15 II 16 A+C A+C ACYW ACYW 2 200
155 20, ,000 10,000 2, ,000 18,000 20,500 % % % , , , , , ,
156 396 26,5003, %1, %
157 % 24.2% 28.5% 36.6% 63.2% 66.6% MENET 34.2%19.7% 74% 41% 1,788
158 MENET 46.6% 31.4% 48% 1,140,000 1,656, % 309 MEMET 18.0% 8.1% 407, , % ,000 1,487, % MEMET 35.0% 12.9% 153
159 1,419,000 6,930, % 1, % 0.1% PEG
160 AIDS-KSPEG
161 90
162
163
164 GMP
165 (1) % % (1)
166 Yiling Yiliang
167 13.3% 6.6% 7.4% 4.5% 2.5% 3.2% 80% 20% 800, ,
168
169
170 29.1% 28.5% 22.1% 9.9% 9.1% 7.3%
171 2,80020, % 2.4% % 85.9% 97.8% 67.2% 70.4% 65.5% State Pharmaceutical (Holdings) Limited
172 Frost & Sullivan II IMS 63.4% 65.6% 60.7% 44.1% 46.6% 46.5% 67.2% 70.4% 65.5% 7.9
173 Frost & Sullivan 10 Frost & Sullivan Frost & Sullivan31.3%39.3% Frost & Sullivan 4% Frost & Sullivan Frost & Sullivan %
174 19 GSP20
175 (i)(ii) ,055 1, % % % % %... 1, %
176 % 3.7% 5.8%
177 12, ,000 43,807
178 B. 107, , , ,920.04
179 19 11,735.8
180 II i) III ii) II III iii) II
181 1 II II III GMP
182 GMP II II III 171
183 46.68% (a) (b) (i) 10% (ii) 5% (i) (ii) 30% (a)
184 (b) (i) (ii) (i) (ii) (i) (ii) (iii) TPG 8.10TPG Star TPG Biotech (i) (ii)
185 (iii) (iv) (v) (vi) (vii) Golden Base
186 28NT Holdings (i) (ii) (iii) 20% 14A
187 %20% (i) (ii) (iii) A.34(1)
188 14A % 5% 14A.45 14A.47 14A 14A.35(1) 14A.35(2) 14A.36 14A.37 14A.38 14A.39 14A.40
189
190 Australian Business Lawyers H Allen Henry Moffitt 48TPG Growth Capital (Asia) LimitedTPG Morningside Technologies Inc LimitedMorningside Morningside Corporate Governance Award Organizing Committee Corporate Finance Committee
191 52 Solomon Systech (International) Limited J.P. Morgan Chartered Association of Certified Accountants Hong Kong Society of Accountants CEI Contract Manufacturing LimitedCEI Spencer Stuart & Associates Tristate Holdings Limited
192 MIT Corporation 60 Gairdner International Award Cresson Medal of Franklin Institute XII Sanremo International Award for Genetic Research (Distinguished Scientist Award from the Medical Research Council, Canada) Killam Prize of Canada Council European Cystic Fibrosis Society Award 35 The Thermal Controls Group 40
193 Smithkline Beecham Smithkline Beecham Glaxo Wellcome 36 Jabil Circuit, Inc. JBL
194 3.21 C3 B
195 A.193A.23 (a) (b) (c) (d)
196 10% (1) Golden Base (2) ,062, % 505,062, % TPG Star (3) ,250, % 146,549, % TPG Biotech (4) ,124, % 73,273, % (1) (2) Golden Base 50%Golden Base Golden Base Golden Base 50%Golden Base Golden Base (3) David Bonderman James CoulterTPG Star 146,549,000 ANT Holdings TPG204,250,170 TPG StarTPG Star, L.P. TPG Star, L.P. TPG Star GenPar, L.P. TPG Star GenPar, L.P. TPG Star GenPar Advisors, LLC TPG Star GenPar Advisors, LLCTPG Holdings I, L.P. TPG Holdings I, L.P. TPG Holdings I-A, LLC TPG Holdings I-A, LLCTPG Group Holdings (SBS), L.P. TPG Group Holdings (SBS), L.P. TPG Group Holdings (SBS) Advisors, Inc. TPG Group Holdings (SBS) Advisors, Inc.David Bonderman James Coulter (4) David Bonderman James CoulterTPG Biotech 73,273,000 ANT Holdings TPG102,124,830 TPG BiotechTPG Biotechnology Partners III, L.P. TPG Biotechnology Partners III, L.P. TPG Biotechnology GenPar III, L.P. TPG Biotechnology GenPar III, L.P. TPG Biotechnology GenPar III Advisors, LLC TPG Biotechnology GenPar III Advisors, LLCTPG Holdings I, L.P. TPG Holdings I, L.P. TPG Holdings I-A, LLC TPG Holdings I-A, LLCTPG Group Holdings (SBS), L.P. TPG Group Holdings (SBS), L.P. TPG Group Holdings (SBS) Advisors, Inc. TPG Group Holdings (SBS) Advisors, Inc. David Bonderman James Coulter
197 10%
198 626,250,000, , ,437, ,437, ,479, ,081,916, (a) (b) (c) (a) 20%
199 (b) (a) (b) (c) 10% (a) (b) (c)
200 ... 1,413,985 2,395,038 2,667, (1,178,904) (1,915,167) (2,004,775) (1) , , , ,196 7,670 28, (44,311) (1,739) 8, (108,129) (237,418) (354,456)... (43,147) (55,999) (90,056) (1)... 87, , , (14,277) (17,128) (45,379)... 73, , , (20,150) (58,087) (80,748)... 53, , , , , , (2)(3)... 53, , ,410 (1) 7.9 (2) 12.3 (3)
201 % % % , ,479, ,524, , ,230, ,167, , , , , , ,143, , , , , , , ,413, ,395, ,667, % % %... 90, , , , , , , , , , , , , , , , , , , , ,
202 % % %... 50, , , , , , , , , , , , , , , , , , , , , (21,789) (31,449) (59,317)... 87, , ,
203 , , , , , , ,514 1,213,754 1,738, ,262 55,990 47, , , , ,269 1,713,000 2,467, ,066 1,947,188 2,755, ,005 2, ,005 2, ,188 1,042,657 1,358, , , , ,000 6, ,823 54,931 51, ,508 1,608,307 2,250, ,390 1,610,312 2,253, , , , , , , ,130 15,130 15, , , ,277
204 ... (37,699) (251,274) (383,235)... (66,845) (63,019) (57,599) , , , , ,318 (62,730) %23.4%6.9% 10.7% 1 8.7% 1 II 64% II 54% 1 Frost & Sullivan II II II II
205 2 26,5003, % 3 1,250 20% 3 1, , % % 2 Frost & Sullivan 4
206 162 29% 28% 15.8%50.3% 1.6%5.2% 29% 28%
207 58.2% 43.2% 47.5% NT Pharma (Group) Co., Ltd. NT Pharma (Group) Co., Ltd. NT Pharma (Group) Co., Ltd. NT Pharma (Group) Co., Ltd 12.7% 18.9% 37.4% 8,500 I
208 614 III 74 II7.6% , , % 53.8% % 184.1
209 % 80.6% 19.3% 36.5%44.8% 54.1% 75.1%80.6% 22.6% 58.2%36.2% 43.2% 38.1% 47.5% II A+C
210 31.3%39.2% 4 II A+C Meningococcal ACYW 19.7% 13.9% 18.5% 4 Frost & Sullivan
211 8.4% 6.4% 7.4%
212
213
214
215 % 6.6% 1.6% % 2.2% 2.7%26.4%, 8.5% 8.6%
216 2.4% 4.7% 7.2% % % % , ,479, ,524, , ,230, ,167, , , , , , ,143, , , , , , , ,413, ,395, ,667,
217 Glipizide 26.4% 8.5% 8.6% 29.8% 22.4% 30.7%
218 % % % , ,310, ,302, , ,151, ,081, , , , , , , , , , , , , ,178, ,915, ,004, % % %... 1,163, ,912, ,982, (1)... 15, , , ,178, ,915, ,004, (1)
219 % % %... 90, , , , , , , , , , , , , , , , , , , , ,
220 % % %... 32, , , , , , , , , , , , , , , , , (1)... 17, , , , , , (1)
221 % % %... 10, , , , , , , , , , , , , , , , , , , (1)... 12, , , , , , (1) % % %... 50, , , , , , , , , , , , , , , , , , , , , (21,789) (31,449) (59,317)... 87, , ,
222 , , , (25,674) (37,380) (96,163)... 48,196 7,670 28, (44,311) (1,739) 8, (14,277) (17,128) (45,379)... 73, , , NT HoldingsTPG AA NT Holdings ANT Holdings NT Holdings NT Holdings NT Holdings A A TPG
223 ... 73, , , ,429 41,228 56, ,427 21,895 28, (17) (1)... (9,219) (5,348) (7,901)... 3,086 2,684 4, (3,294) (1,115) ,150 58,087 80,748 25% 5% 10% 10% 25% 25%
224 % 33.1% 38.4% % 25% 15% 25% 25%
225 ... 1,413, ,395, ,667, (1,178,904) (83.4) (1,915,167) (80.0) (2,004,775) (75.1) , , , , , , (44,311) (3.1) (1,739) (0.1) 8, (108,129) (7.6) (237,418) (9.9) (354,456) (13.3)... (43,147) (3.1) (55,999) (2.3) (90,056) (3.4)... 87, , , (14,277) (1.0) (17,128) (0.7) (45,379) (1.7)... 73, , , (20,150) (1.4) (58,087) (2.4) (80,748) (3.0)... 53, , , , % 2, , %1, , %1,167.8
226 %356.8 Meningococcal ACWY A+C A+C 2.0% 0.9% 18.8% 6.7% 6.1% 2.3% %1, % %304.9
227 1, % 2, % % 24.9% % % 14.6% % % 7.4% % % 38.1% % % 38.6% %398.6
228 43.2% 47.5% % % % % 13.3% % % 3.4%
229 % 9.6% % % % % % %
230 % 80.7(i) (ii) (iii) 33.1% 38.4% % % 1, % 2, %1, %1, %
231 % % % % , % 1, % % 20.0%
232 % % 11.5% % % 6.4% % % 36.2% % % 33.9% % % 43.2% % % 13.9%
233 % % % 9.9% % % 2.3% % % 8.0% %107.3
234 % % % % % % % % 4.9%
235 74 Frost & Sullivan II 7.6% 1,
236 19.0% 26.2% 30.5%... 64,884 66, , (37,699) (251,274) (383,235)... (66,845) (63,019) (57,599) , , , , ,318 (62,730)... 66, , , (i) 298.1(ii) 525.4
237 (iii) (i) (ii)646.3 (iii) (i) 43.5 (ii)236.8 (iii) (i) 72.1 (ii) 27.1
238 378.1 (i) (ii) (i) (ii) (i) 35.2(ii) , , , , ,514 1,213,754 1,738,213 1,746, ,262 55,990 47,080 45, , , , , ,269 1,713,000 2,467,260 2,393, ,188 1,042,657 1,358,270 1,284, , , , , ,000 6, ,823 54,931 51,941 54, ,508 1,608,307 2,250,398 2,175, , , , ,681
239 ,560 9,899 7, ,221 3,472 1, , , , , , , (i) (ii)
240 (iii) % %231.0 % % % , , , , , , , , , , , , , , % (1) (1) ,236, (i) (ii) (iii)
241 ,403 1,083,657 1,544, ,870 27,162 22, ,755 99, , ,486 2, ,514 1,213,754 1,738,213 % % % , , , , , , , , , , , , , , , ,110, ,566,
242 42.4% 57.6% % % , , , , , , , , , , , , , , , , , ,566,710 % % , , , , , , , , , , , , , , ,110,819 % % , , , , , , , , , , , , , , , , , , ,110.8
243 1,566.7(i)(ii) (iii) % 2.4% % 120
244 ,566.7 ) % ,783 49, , , ,566, , % %... 8, , , , , , , , , , , , , , , , a % b. 41
245 c. d. e. 15.9% b c d e f. g. h i ,194 5,030 13, ,238 3, (164) (3,782)... 5,030 13,268 12,595
246 (1) (1) ,972, (i) (ii)
247 , , , , , , ,564 69, , ,094 18, ,379 7,559 13, ,351 21, ,188 1,042,657 1,358,270
248 (%) (%) (%) , , , , , , , , , , , , , , , (1) (1) ,499,
249 % NT Holdings 28(c) ,000 25, , , , , , , ,103 5, , , , ,684
250 , , , , , , , ,845 52, ,441 6, , , , ,262 45,562 25, , , , NT Holdings 24
251 % %
252
253 ... 7,965 7,456 6, ,137 6,831 3, ,102 14,287 9, ,353 13,864 10, ,693 10,184 56,046 24,048 10,883
254 5.9% 0.7% 3.3% % 7.0% 5.0% 27.0% 21.0% 13.8%
255 % 129, % 365, % 690, % 5.91% 6.12% % 70, % 6, , , , % (42,410) 0.75% (36,845) 2.22% 129, , , % 1.95% 2.11% 5.18% 56, % 75, % 142, % 0.36% 0.01% 1.71% (51,262) 1.71% (13,580) 1.91% (10,235) % 0.01% 0.01% 0.36% (67,803) 0.36% (212,240) 0.36% (154,913) (62,325) (150,304) (22,375) , , , , ,000 42,000
256 5% %
257 ,081,916,
258
259 1, % % %
260 10% % % %
261 (1) (a)
262 (b) (c) (d) (e) (f) (g) (h) (i) (j) (k) (l) (m)
263 (n) (1) (2) (3) (4) (2) (a) (b) (c) (d) (e)
264 (f) (g) (a) (b) (c) (a) (b) (d) (a) (b) (c) (a) (b) (c) (a) (b) (c)
265 (a) (b) (c) (i) (ii) (iii)(i) (ii)(iv) (i) (ii) (iii) (i) (ii) (iii) (a)(i) (ii) (iii) (a)(i) (ii) (iii) TPG (i) (ii)
266 (iii)(i) (ii) (iv) (i) (ii) (iii) (i) (ii) (iii) (a) 10.07(2) (b) (a) 155 (b) 3% 1%
267 ,554,000 15%
268 (a) 35,703,500 (b) 144A 321,328,500 35,703,500 10% (i) (ii) 3.3%
269 A B A 17,852, B 17,851, AB AB 17,851,500 (i) 15 50(ii) (iii) ,110,000(i) 142,813,000(ii) 178,516,000(iii) 30% 40% 50% A B
270 ,328, ,775,500 86,553,000 90%
271 30 40,571,50012,982,500 53,554,000 15% 4.77% (a) (b) (c) (a) (b) (d)
272 (e) (f) (b) (c) (d) (e) 30 53,554,000 15% Golden Base TPG Golden Base TPG 53,554,00015% Golden Base TPG 10.07(1)(a)
273 10.07(3)(a) (b) Golden Base TBG Golden Base TBG 1% 0.003%0.005%
274 10% ,256.0
275 (a) (b) (c)
276 (i) (ii) (i) (ii)
277 (i)(ii) (iii) 18 S (
278 1. (1)
279 (2) B (3) (4)
280 (a) (b) (c) (d) (a)
281 (b) (i) (ii) (c) (i) (ii) (d) (i) (ii) 2. eipo
282
283 ( (a) (b)
284
285
286 E (i) (ii) 4.
287
288 17,851,50050% % 0.003% 0.005%500 3, ,851,500
289 6. 1% 0.003%0.005% 1% 0.003%0.005% % 0.003%0.005% 7.
290 (1) (1) (1) (1) (1) 1 24
291
292 10. (a) ( ( ( E ( (
293 (b) (c) (d) (
294 50% (a) (i) (ii) (b) (i) (ii) (iii) 1% 0.003%0.005%
295 (c) 1% 0.003%0.005% (a) 1,000,
296 1,000,0001,000,000 (b) 1,000,000 1,000,000 1,000,000
297 (c) 1,000, ,000,000 (d)
298
299 A NT Pharma (Group) Co., Ltd. Kimford Investment Limited Goldwise Resources Limited Tai Ning Pharmaceutical (Investment) Company Limited Farbo Investment Limited Humford Limited
300 C 31 AC A
301 A NT Pharma (Group) Co., Ltd. NT Pharma (Group) Co., Ltd. NT Pharma (Group) Co., Ltd. B NT Pharma (Group) Co., Ltd. B NT Pharma (Group) Co., Ltd.
302 NT Pharma (Group) 2 100% Co., Ltd. Kimford Investment Limited 1 100% Kimford Goldwise Resources Limited 1 100% Tai Ning Pharmaceutical 1 100% (Investment) Company Limited Farbo Investment Limited 1 100% Humford Limited 1 100% NTP (China) Investment 15,000, % Co., Limited NT Pharma (HK) Limited 2 100% 2,000, % 100% 10,000, % 20,000,000 3,370, % 100% 100,000,000
303 100% 50,000,000 80% (i) 55,625,000 11,851, % 100% 166,600, , % 20,030, % (i) 80%Kimford Kimford % Kimford , ,000
304 B 1 C ,413,985 2,395,038 2,667, (1,178,904) (1,915,167) (2,004,775) , , , ,196 7,670 28, (44,311) (1,739) 8, (108,129) (237,418) (354,456)... (43,147) (55,999) (90,056)... 87, , , (a) (14,277) (17,128) (45,379) , , , (a) (20,150) (58,087) (80,748)... 53, , , , , , , , ,410
305 , , , ,284 (86) 11, , , , , , , , , ,395
306 3 C , , , ,633 15,309 32, , , , ,441 10,444 2, ,908 39,904 37, ,250 1,250 1, (b) 899 3,812 5, , , , , , , ,514 1,213,754 1,738, ,262 55,990 47, , , , ,269 1,713,000 2,467, ,188 1,042,657 1,358, , , , ,000 6, (a) 12,823 54,931 51, ,508 1,608,307 2,250, , , , , , ,
307 C... 21(b) , , , , , , , , , , , ,130 15,130 15, , , ,277
308 4 24(b) 24(c)(i) 24(c)(ii)24(c)(iii) 24(c)(iv)... 22,528 28,336 8,256 72, ,999 15, , ,263 53,263 53, ,284 15,284 15, ,284 53,263 68,547 68, ,195 (8,195)... 37,812 36,531 8, , ,546 15, , , , , (86) (86) (86)... (86) 117, , , ,116 4,116 4, ,370 (8,370)... 37,726 44,901 8,256 4, , ,746 15, , , , , ,985 11,985 11, , , , , (800) (800)... 24,806 24,806 24, ,458 (20,458)... 49,711 65,359 8,256 28, , ,147 15, ,
309 5 C... 73, , , (1,722) (1,186) (619)... 3 (45,980) , (527) , (a) 14,277 17,128 45, (b) 4,116 24, (c) (c) 4,595 4,117 4, (c) 6,096 4,864 12, ,627 (127) , , , (43,499) (105,326) (298,095)... (236,758) (646,267) (525,400) , , , (31,069) (233,505) (298,355)... (8,115)... (6,630) (17,769) (76,765)... (37,699) (251,274) (383,235)
310 C... (72,055) (63,619) (51,167)... (17,528)... (27,087) (4,113) (1,680)... 1, , ,722 1, ,503 (4,728) 8, ,494 8, (66,845) (63,019) (57,599) ,095 2,067,928 2,085, ,000 16, (619,268) (1,812,853) (1,696,263)... (80,000)... (14,277) (17,128) (45,379) , ,664 98, (800) , , , , ,318 (62,730)... 64,884 66, , (1,607) (12) , , ,810
311 C 1 (a) C (b) A (c)
312 29 (d) (e) (i)
313 (ii) (ii) (i) 1(j) (f) 1(j) (g) 1(j) 1(v)
314 (h) (i) 1(j) 10 (ii) 1(j) 32 (iii) GSP GSP 1(j) (iv) 1(j) 10 (v) 1(j) (vi) 1(j) 5 10
315 (i) (j) (i)
316 (ii)
317 (k) (l) 1(j) (m) (n) (o)
318 (p) (i) (ii) (q)
319 (i) (ii)
320 (r) (i) (i)(ii) 1(r)(ii) (ii) (s) (i)
321 (ii) (iii) (iv) (t) (u) (v)
322 (w) (i) (ii) (iii) (iv) (v) (i) (vi) (x) ,380,405 2,281,867 2,475, , , ,650 1,413,985 2,395,038 2,667,978
323 10 10% (a) ,722 1, , ,076 25, ,812 48,196 7,670 28, (20,259) (619) (16,493)... (7,559) (1,120) 7,621 (44,311) (1,739) 8,148
324 5 (a)... 14,259 12,980 36, ,325 5,507 9, ,584 18,487 45,982 *... (2,307) (1,359) (603) 14,277 17,128 45,379 * 6.14% 8.22% 5.35% 8.22% 5.35% 5.84% (b)... 7,248 10,921 19, ,409 73, , ,116 24,806 56,657 89, ,746 10% 22%
325 5% 20,000 (c) ,595 4,117 4, ,096 4,864 12, ,071 8,443 8,327 14(b)... 1,163,757 1,912,316 1,982,422
326 6 (a) , , ,277 55,204 70, ,453 56,127 70, (1,790) (1,451) (1,790) (1,451) ,150 58,087 80,748
327 (b)... 73, , ,158 (i) (ii) (iii)... 19,429 41,228 56, ,427 21,895 28, (17) (1) (iii)... (9,219) (5,348) (7,901)... 3,086 2,684 4, (3,294) (1,115) ,150 58,087 80,748
328 (i) (ii) 16.5% (iii) 33% 25% 15% 15% 15% 25% 18% 20% 22% 24% 25% 9% 10% 11% 24% 25% (iv) 10% 25%5%
329 7... 5, , , ,665
330 ... 2, , , ,008
331 ... 3, , ,702 4, ,126 4, ,702 7,913 1(p)(ii) 8
332 ,221 2,894 2, ,331 5,285 2,360 4,343 7, ,000, ,000,001 1,500, ,500,001 3,000, ,000,001 3,500, A
333 10 (a)
334 ,334 1,230,340 1,167,767 89, , , , , , , , ,861 1,413,985 2,395,038 2,667, (770,613 ) (1,151,063 ) (1,081,478 ) (68,981 ) (159,090 ) (220,917 ) (76,915 ) (355,457 ) (439,919 ) (262,395 ) (249,557 ) (262,461 ) (1,178,904 ) (1,915,167 ) (2,004,775 )... 70,721 79,277 86,289 20,112 90, , , , ,643 37,104 40,201 42, , , , ,626 47,100 44,970 9,771 60,216 64,888 46, , ,741 12,862 13,119 10, , , , ,874 4,628 7,421 2,916 2,002 4,026 9,105 6,980 12,025
335 (b)... 1,413,985 2,395,038 2,667, , , , (25,674) (37,380) (96,163)... 48,196 7,670 28, (44,311) (1,739) 8, (14,277) (17,128) (45,379)... 73, , ,158
336 ,324 22, ,457 3,869 3,926 14,435 71,673 33, , (9) (81) (19) (65) (174) (174) , ,592 60,614 60, (18,472) (12,800) (127) (31,399) (17,376) (48,775)... 2,852 10, ,416 4,241 4,378 68, ,714 16, , ,443 6, ,314 1,893 1,660 17,582 1,104 18, (2) (15) (11) (40) (68) (68)... 1,437 2, , , (4,376) (5,072) (114) (9,562) (883) (10,445) , ,152 2,597 2,138 14, , ,348 7, ,264 1,644 2,240 68,027 86,666 15, ,299
337 ... 2,852 10, ,416 4,241 4,378 68, ,714 16, , , ,818 1, ,398 82,539 82, (12) (1,173) (651) (78) (1,914) (1,914)... 93,445 15,558 (109,003)... 96,297 28, ,062 5,541 4,404 35, ,341 16, , , ,152 2,597 2,138 14, , , , , , (5) (642) (345) (48) (1,040) (1,040) , ,430 2,983 2,767 17, , ,661 23, ,632 2,558 1,637 35, ,469 15, ,778
338 ... 96,297 28, ,062 5,541 4,404 35, ,341 16, , (6) (38) (12) (52) (108) (108)... 4,088 1, ,957 1,570 3,179 48,027 60,844 17,528 78, (2,851) (367) (32) (701) (3,951) (3,951)... 46,307 13,699 (60,006) ,841 43, ,981 7,067 6,830 23, ,126 33, , , ,430 2,983 2,767 17, , (3) (6) (8) (28) (45) (45)... 5,209 3, , ,166 12, , (649) (6) (576) (1,231) (1,231)... 5,196 8, ,460 3,738 3,329 29,267 1,229 30, ,645 35, ,521 3,329 3,501 23, ,859 32, ,336
339 (a) (b) 73,583, ,826, ,372,000 (c) 93,445, ,136, GSP... 7,283 9,330 7, ,663 26, (32) (32)... 30, , , , , , , , ,456 6, , ,332 1, , , , , , , ,099 7,030 29, ,315 42,908
340 GSP... 7,283 9,330 7,030 30, ,750 56, , , , , , , , , ,184 9,330 1,000 1,435 13, , , , , , , , ,371 7,030 26,000 1,224 1,279 39,904 GSP... 7,283 9,330 7,030 30,000 1,224 3,103 57, (17) (17)... 1,680 1, , , , , , , , ,912 9,330 4,000 1,824 18, , , , , , , , ,643 7,030 23,000 1,207 2,294 37,174
341 (a) (b) (c) GSP GSP GSP 15.6% 16.2% 14.2% ,250 1,250 1, ,250 1,250 1,250
342 % % % (a)... 2,560 9,899 7, ,221 3,472 1, , , , , , ,054 20,845,000 52,971,00019
343 (b)... 1,161,315 1,908,591 1,977, ,442 3,725 5,114 1,163,757 1,912,316 1,982, ,303 1,124,087 1,579,305 15(b)... (5,030) (13,268) (12,595) 534,273 1,110,819 1,566, ,755 99, , ,486 2, ,514 1,213,754 1,738,213 1,720,000 1,576, ,000 66,339, ,672, ,694,00019
344 (a) , , , , , , ,580 44, , ,214 10, , , , ,273 1,110,819 1,566, (a) (b) 1(j)(i)... 5,194 5,030 13, ,238 3, (164) (3,782)... 5,030 13,268 12,595
345 5,742,000 14,375,000 17,541,000 5,030,000 13,268,000 12,595,000 (c) , , , , , , ,084 43,793 87, ,449 20, , , ,428 95, , , ,561 1,109,712 1,561, ,000,000 96,720, ,712,
346 , , , (869) (5,103)... 66, , ,810 67,136, ,870, ,785, , , , ,564 69, , ,094 18, ,379 7,559 13, , , , ,351 21, ,188 1,042,657 1,358,270
347 , , , ,438 31, , ,856 2,007 6, ,301 1,676 69, , , , , , ,687
348 , , , , , ,000 25, , , , , , , , ,600, ,188, ,380, ,497, ,870, ,579, , , , ,441 6, ,845 52, , , , ,262 45,562 25, , , ,226 72,600,000Rich Great International Industries LimitedRich Great Rich Great
349 181,446,000 Rich Great NT Pharma (Holdings) Company Limited 587,776,000 NT Pharma (Holdings) Company Limited 28,116,000 25(c) % 21 (a)... 3,750 7, ,823 51,181 44,724 12,823 54,931 51,941
350 (b)... 3,089 (2,080) (1,780) 61 (710)... (4) (4)... (276) (57) ,813 (1,634) (1,196) (17)... 2,813 (1,634) (1,196) (17)... (73) (2,913) 1,196 (1,790)... 2,740 (4,547) (1,807)... 2,740 (4,547) (1,807)... (79) (1,372) (1,451)... 2,661 (5,919) (3,258)... (899) (3,812) (5,919) ,005 2,661 (17) (1,807) (3,258)
351 (c) 1(q) 29,428,000 18,689,000 33,363, ,000 6,508,000 6,274,000 18,967,000785,000 (d) 80,329, ,386, ,718, , , (45,980)... 45,980, NT Pharma (Holdings) Company LimitedNT Holdings NT Holdings NT Holdings
352 NT Holdings NT Holdings (a)... 19,335, ,335, ,335, ,582, ,582, ,582, ,666, ,666, ,666, ,166, ,166, ,166, , , , , , , , , , ,055,723
353 (b)... 58,007, ,007,799 42,047, (10,141,366)... 58,007,799 89,914, ,412,341 NT Holdings58,007, NT Holdings88,714, ,200,000 70% (c) % % 58.23% 58.00% 59.51% 58.94% 53.10% 57.19%... 0% 0% 0% 0% 0% 0% 0% % 4.378% 4.293% 4.072% 3.415% 3.241% 3.858%
354 24 (a) (b) NT Pharma (Group) Co., Ltd , ,250,000, NT Pharma (Group) Co., Ltd (c) (i) 1(u) (ii) 10% 50%
355 (iii) (iv) NT Holdings 1(p)(ii) (d) 19.0% 26.2% 30.5% 25 (a) (i)
356 9.2% 7.0% 5.0% 27.0% 21.0% 13.8% 27 (ii) (b) , , ,628
357 ,002 4,183 10, , , ,689 3,266 7, , ,584 (c) (i) (i) 4.86% 1.06% 2.05% % 129, % 365, % 690, % 70, % 6, , , , % % (42,410) 2.22% (36,845) 129, , ,
358 1.70% 1.95% 2.11% % 56, % 75, % 142, % 0.36% 0.01% % (51,262) 1.71% (13,580) 1.91% (10,235) 0.13% 0.01% 0.01% % (67,803) 0.36% (212,240) 0.36% (154,913) (62,325) (150,304) (22,375) , , ,194 (ii) , ,000 42,000 (d)
359 (i)... 26, ,262 42,409 25, ,617 40,550 5, (34,784) (81,771) (93,140) (22,746) (69,557)... (92,097) (72,706) 22,095 (64,648) (93,140) (65,134) (69,557) (ii)... 5% 829 5% (2,424) 5% (2,443) (5)% (829) (5)% 2,424 (5)% 2, % 5% (3,493) 5% (2,608) (5)% (5)% 3,493 (5)% 2,608
360 (e) 26 (a)... 43,353 13,864 10, ,693 10,184 56,046 24,048 10,883 (b)... 7,965 7,456 6, ,137 6,831 3,340 17,102 14,287 9,709
361 27 Rich Great Rich Great 15,401, Rich Great International Industries Limited NT Pharma (Holdings) Company Limited (a)... 9,873 15,161 13,106
362 (b) ,219 7,814 10, ,270 13,421 9,219 10,084 23,507 5(b) (c) NT Pharma (Holdings) Company Limited... 2,476 2, ,010 3,486 2, NT Pharma (Holdings) Company Limited , , ,955 Rich Great International Industries Limited... 2, ,259 6, , , , ,351 21,363
363 NT Pharma (Holdings) Company Limited NT Pharma (Holdings) Company Limited 60 (d)... 72, , ,775 (e) NT Pharma (Holdings) Company Limited , ,775 (f) 72,600,000 60,314,000Rich Great Rich Great Rich Great 29
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