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- 钦彪 澹台
- 9 years ago
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1
2 , BSc, ACGI, MBA, BSc, MBA, BEc, CA, BA, BA, LLL, JD, BSE, MA, MA, EdM, Solicitor, FCIS, FCS (PE), BSc, MBA, ACGI, MA, MBA, HonFCGI, BA, BMBCh, PhD, DM, DSc, FSB Panmure Gordon (UK) Limited Panmure Gordon (UK) Limited UBS Limited
3 *
4 2
5 3 106% 4,6002, % % ,690 3,080 9,900 6,240 13% % % 5,160 20% 1,8601, % 327% 2, , , Nutrition Science Partners LimitedNSP 880 NSP HMPL 004 NSP NSP
6 4 AstraZeneca AB (publ) c Met Volitinib(HMPL 504) 500 PRCC Fruquintinib(HMPL 013) VEGFR 8,650 15% HMPL ,050 Sulfatinib Syk HMPL % 1,2501,
7 5 NSP HMPL-004 NATRUL-3 NATRUL-4 NATRUL-3 (HMPL-013) (HMPL-504) HMPL- 507 / HMPL-507 5,480 HMPL-523
8 6 14% 1,86020% 51% 20% 141 1,227 43% GMP 40 2, %
9 (17.3) (2.5) ( NSP) 11 ( NSP) The Hain Celestial Group, Inc. (Nasdaq: HAIN)Hain Celestial 4,690 1,030 5,150 3,000 2,690 NSP 9, ,140
10 % 4,600 2, % 2, % 1,2501,020 25% % Hain Celestial
11 9 (1) 18.6 (+20%) 29.5 (+327%) (2.4) (-187%) 12.5 (+23%) (0.5) (+45%) (1) (+13%) % 63% % 13% % GSP 5,5605,570 20% 1,8601,550 (i) ( ) 50%(ii) ( ) 50% (iii) 600 (1)
12 10 (1) ( +13% ) (+21%) 74.2 (+13%) 71.9 (+20%) 16.3 (+0%) 12.4 (+6%) 10.1 (+46%) 3.4 (-23%) 82.7 (-1%) (1)
13 11 ( ) 19% ( ) % ( ) % % 20% 10% 1,227 31% 4.6%5.4% 16% 11% % - 7.0% 6.4%
14 12 () 22% ( ) 401 (30%) 317 (24%) 223 (17%) 160 (12%) 432 (32%) 473 (35%) 536 (40%) 8, %14% 11% 12% 46% 1,760 43% 1,58043% 23.1% 21.3% 1) 2) 3) 4) 5)
15 13 > 1, , < % % 2% 88%
16 14 19% % % % 13.1% 19% 12% 65 7% 4% 21% % 11% 6,260 5,620 25% 7,5506,030 55% 38% 1,500 6% 1,240 1,160
17 15 > 1, , < % % 1% 4% 7% 30% 29%
18 16 1,600 1,500 13,000 10,000 24,000 54% GMP 13 78, GMP % 28 9 GSP 70.2% 67.9% 80% 7% 13% 7,420 6, H1N1 8 10% % GSP 2% 5,160 5,
19 17 20% 7,1906,020 24% 24% 4% 4,5004,9004,700 7, ,000 6,500 20, % GMP ,000 GMP
20 % % 49% 5, ,990 2,700 25% % DHA omega-3
21 19 86,100 59, , ,000 58,000
22 20 Hutchison MediPharma Holdings Limited 2 HMPL 004 HMPL 507 NSP50% 7, HMPL 004 (Sulfatinib, HMPL 012) Epitinib(HMPL 813) Theliatinib(HMPL 309)
23 21 HMPL-004 HMPL-004 (HMPL-013) (HMPL-012) (HMPL-813) (HMPL-309) (HMPL-504) Syk (HMPL-523) FGFR (HMPL-453) (HMPL-507) % 1% 7% 6% 20 24% 327% 2, NSP NSP 880NSP 1,750 NSP 1, ,
24 22 NATRUL 3 NATRUL 4 NSP 3,010 1,310 VEGF 8, % / HMPL , NSP 12.2% 1,250 NSP 12.2% (i) HMPL 523 HMPL 453 HMPL 507 (ii) (iii) HMPL 004 NSP
25 23 HMPL 004 NSP HMPL (5 ASA) 5- COX LO PPARγ HMPL-004 ~70% 40-60% ~70% HMPL 004 2,000~7,000 15,000~20,000 HMPL 004 HMPL 004 HMPL 004 HMPL NATRUL 4 HMPL 004 1,80052 NATRUL 3 NATRUL 4 HMPL 004 NSP NSP NATRUL 3 HMPL 0041,800 2,4008 (5 ASA) 6513 NATRUL 3 HMPL 0042,700
26 24 EGFR VEGFRc Met Syk FGFR PI3K (HMPL 504) c Met c Met c Met c Met c-met 30 PRCC PRCC 10 15% PRCC c Met c Met PRCC c Met PRCC PRCC c Met
27 25 VEGF/VEGFR VEGF VEGF VEGF/VEGFR Sorafenib Nexavar TM Sunitinib Sutent Bevacizumab, Avastin TM 61 VEGF/VEGFR (HMPL 013) VEGF VEGFR1 VEGFR2 VEGFR3 VEGFR 30% (ORR) 38%4/ 46% 18% 2% 40 5 / 4 / 58 GMP
28 26 (HMPL 012) (VEGFR) VEGFR FGFR VEGFR FGFR I 57 EGFR EGFR EGFR EGFR EGFR EGFR EGFR EGFR 10 30%EGFR
29 27 Tarceva TM Iressa 14 6 Erbitux 18 EGFR (1) EGFR (2) EGFR (3) EGFR T790M (n=13) EGFR (HMPL 813) EGFR EGFR 30 40% EGFR EGFR 8 10% 50% EGFR EGFR EGFR EGFR
30 28 (Theliatinib, HMPL 309) EGFR EGFR EGFR EGFR EGFR EGFR EGFR I EGFR EGFR B B Rituximab Rituxan TM MabThera TM Syk B B Syk Fostamatinib GS 9973Gilead Sciences HMPL 523 Fostamatinib Fostamatinib HMPL 523 GLP HMPL 523 I HMPL 523 Syk HMPL 453 (FGFR) HMPL 507 HMPL HMPL HMPL 523 HMPL 523 Syk SykB HMPL MPK = / QD = BID = QOD = PO = IP = Naïve = Fostamatinib SYK R406
31 29 23% 1,250 1, Hain Celestial Hain Celestial Sen Sen 39%, 2,870 4%, 290 (Euromonitor) Avalon Organics Earth s Best Imagine Terra Walnut Acres Organic Health Valley 45 Hain Celestial 23% 1, % % %, 1,810 1%, 80 32%, 2,420 51% % % 91% 170
32 30 HMPL-004 NATRUL-3 Syk HMPL-523
33 Hutchison MediPharma (Hong Kong) Limited Sen Medicine Company Limited
34 Hutchison Whampoa Japan K.K Hutchison Whampoa Luxembourg Holdings S.à r.l. (ITU) GSMA Limited Asia Task Force Transport Initiatives Edinburgh Ltd. FPT Group Limited Railtrack Group plc Biological Reviews, the Journal of Physiology and Europace (B.A.) (B.M., B.Ch.) (Ph.D.) (D.M.) (D.Sc.) (FSB) 55 NTR plc GKN Evo edrive Systems Ltd Gasrec Limited Current OpenGrid Limited Global Crossing Ltd. North West Water International Ltd. S.G. Warburg and Co. Ltd.
35
36 34 91(1) , , ,600 26,506 20,000 2,475 (i)
37 (1) 768, , (3) 64,038 64, (1) 76,818 76, (2) 26,808 26, (4) 43,857 (3,000) 40, (3) 102, , (3) 227,600 (50,000) 177, (3) 150, , (3) 896, , ,459, ,386 (3,000) (50,000) 2,303,317 (1) AIM 50% 25% (2) (3) 25% (4) (ii) Hutchison MediPharma Holdings Limited ( )
38 (1) 1,243,000 (1,186,000) 57, (1) 234,000 (184,000) 50, (1) 360,000 (60,000) 300, (1) 206,000 (181,000) 25, (1) 240,000 (240,000) (1) 562,385 (455,965) 106, (1) 299,120 (299,120) ,144,505 (2,606,085) (2) 538,420 (1) 25% (2) 2,606,085(i) 2,485,189 / (ii) 120,896 3% Hutchison Healthcare Holdings Limited (1) ( HHHL ) 36,666, % Computershare Company Nominees Limited (2) ( CCNL ) 15,295, % CCNL Chase Nominees Limited 2,768, % Slater Investments Limited (3) 3,170, % (3) 2,640, % (1) HHHLHHHL (2) CCNL SC (3)
39 37 4th Floor, Hutchison House, 5 Hester Road, Battersea, London SW11 4AN
40 38 AIM (
41 39 100% 4/4 4/4 4/4 4/4 4/4 4/4 4/4 4/4 4/4
42 40 AIMAIM AIM AIM 47
43 41 100% 4/4 4/4 4/4
44 42
45 43
46 44 AIM 100%
47 45 20,128 (1) (4) 20, ,974 (2) (4) 602,564 14,423 22,846 (5) 977, ,016 (2) 203,846 20,266 (5) 486,128 20,128 (3) 20,128 20,128 (1) 20,128 20,128 (3) (4) 20,128 53,138 53,138 53,138 53,138 53,138 53, , ,410 14,423 43,112 1,703,861 (1) (2) 20,128 (3) (4) (5)
48 46 100% Investor Relations 4th Floor, Hutchison House, 5 Hester Road, Battersea, London 100% [email protected]
49
50 ,970 22,367 (22,208) (12,754) 23,762 9,613 (3,452) (5,694) (21,295) (21,376) 6 (a) 1,603 1,871 6 (b) 11, ,937 17, ,555 13,037 8 (1,485) (1,160) 10,070 11,877 9 (1,050) (1,116) 9,020 10, (1,978) (7,221) 7,042 3,540-7,323 9,472 - (1,408) (5,834) 5,915 3, ,127 (98) 7,042 3,540-11(a) (b) (a) (b)
51 49 7,042 3,540 3, ,384 4,202-10,360 10,616 - (1,503) (6,248) 8,857 4,368 1,527 (166) 10,384 4,202
52 ,028 3,344 4, ,508 1,498 1, , , ,552 66, , ,081 87, ,420 1,590 4, ,410 9,508 12,168 3,356 1,583 2, ,985 1,194 5, ,863 30,767 42,525 67,034 44,642 66, , , , ,051 52,048 51,743 36,819 18,530 13,042 88,870 70,578 64, ,966 11,620 11, ,836 82,198 76,109
53 ,163 3,183 4, ,389 15,229 11, ,374 6,303 5, ,508 10,892 29, ,434 35,607 52,087 4, ,397 2,528 1, ,467 20, ,923 2,397 41,918 26,447 80,831 77,525 78,534 (11,400) 9,035 14, , , , , , ,643
54 52 51,743 92,955 4,748 8, (93,807) 64,785 12,545 77,330 2 (1,221) (1,221) 51,743 92,955 4,748 8, (93,807) 64,785 11,324 76,109 3,638 3,638 (98) 3, (68) (68) ,638 4,368 (166) 4,202 22(a) (390) (180) (b) 1,000 1,000 30(a) (538) (538) 52,048 93,669 4,974 9, (89,989) 70,578 11,620 82,198
55 53 52,048 93,669 4,974 9, (89,989) 70,578 13,070 83,648 2 (1,450) (1,450) 52,048 93,669 4,974 9, (89,989) 70,578 11,620 82,198 5,915 5,915 1,127 7, ,280 2, ,618 2,942 2, ,342 2,942 5,915 8,857 1,527 10,384 22(a) 3 6 (2) (168) (120) (243) 9,459 9,096 3,371 12,467 30(a) (577) (577) 52,051 93,675 5,016 12, (74,447) 88,870 15, ,836
56 54 28 (4,065) (18,123) (1,485) (1,160) (1,181) (393) 11,308 7,837 5,028 (11,451) (2,500) (430) (4,169) 11 (2,500) (4,588) 1,516 (577) (538) 1,000 26,923 14,261 (568) (18,839) (6,519) 13,123 4,172 15,651 (11,867) 30,767 42, ,863 30, ,863 30,767
57 P.O. Box 309, Ugland House, Grand Cayman, KY1-1104, Cayman Islands AIM 2 IFRS 11,400,000 26,923,000 IASB IAS 1IFRS 11 IFRS 12 (A) IAS 1 (B) IFRS 11
58 56 2 IFRS 11 (i) i) ii) iii) iv) v) (ii) IAS 28 IFRS 11
59 57 2 (195,977) 100,400 (95,577) 57,070 24,978 (1,231) 10,937 (3,823) 21 (3,802) 3,802
60 58 2 (24,440) (16,405) (8,059) (15,144) (36) 111,405 (1,756) 45,565 (31,162) (32,168) (6,526) 1,896 (49,578) (117,538) (71,973) (1,700) (1,700) (20,797) (43,585) (1,378) (410) (66,170) (3,861) (242) (4,103) (70,273) (51,368) (5,803) (71,973)
61 ,531 (173,164) 22,367 (98,135) 85,381 (12,754) 97,396 (87,783) 9,613 (60,595) 54,901 (5,694) (34,747) 13,371 (21,376) 2,602 (731) 1,871 11,476 11,476 17,147 17,147 16,132 (3,095) 13,037 (1,209) 49 (1,160) 14,923 (3,046) 11,877 (4,162) 3,046 (1,116) 10,761 10,761 (7,221) (7,221) 3,540 3, ,202 4,202 10
62 ,848 (19,504) 3,344 23,277 (18,727) 4,550 10,440 (8,942) 1,498 6,175 (4,652) 1,523 8,311 (7,904) 407 8,248 (7,841) ,585 (15,585) 14,858 (692) 14, (32) 31 (31) 109, ,552 66,690 66,690 1,639 (1,359) 280 1,550 (1,160) ,855 56, ,081 54,139 33,587 87,726 25,318 (23,728) 1,590 28,720 (24,393) 4,327 44,343 (34,835) 9,508 51,573 (39,405) 12,168 3,940 (2,357) 1,583 5,063 (2,842) 2,221 15,000 (13,806) 1,194 1,516 4,160 5,676 62,009 (31,242) 30,767 53,763 (11,238) 42, ,610 (105,968) 44, ,635 (73,718) 66, ,465 (49,742) 159, ,774 (40,131) 154,643
63 ,048 52,048 51,743 51,743 18,530 18,530 13,042 13,042 70,578 70,578 64,785 64,785 13,070 (1,450) 11,620 12,545 (1,221) 11,324 83,648 (1,450) 82,198 77,330 (1,221) 76,109 18,897 (15,714) 3,183 16,451 (11,510) 4,941 43,715 (28,486) 15,229 35,568 (23,656) 11,912 6,303 6,303 5,345 5,345 11,202 (310) 10,892 30,038 (307) 29, (951) 1,074 (916) ,068 (45,461) 35,607 88,476 (36,389) 52,087 2,692 (2,692) 6,919 (2,368) 4,551 2,667 (139) 2,528 1,911 (153) 1,758 12,467 12,467 20,138 20,138 26,923 26,923 44,749 (2,831) 41,918 28,968 (2,521) 26, ,817 (48,292) 77, ,444 (38,910) 78,534 69,542 (60,507) 9,035 52,159 (37,329) 14, ,397 (4,281) 124, ,298 (3,742) 102, ,465 (49,742) 159, ,774 (40,131) 154,643
64 62 2 (C) IFRS 12 IFRS (a) 2(d) (b) 2(d) (c)
65 63 2 (d) (e)
66 64 2 (f) 2(I) (g) 2(f) (h)
67 65 2 (i) (j) (k) (l)
68 66 2 (m) (n) (o) (p) (q) (r)
69 67 2 (s) (t) (i) (ii) i)ii) iii) (u) (v) (w)
70 68 2 (x) (y) (i) (ii) (iii) (iv) (v) (z)
71 69 2 IAS 19 (2) IAS 32 (1) IAS 36 (1) IAS 39 (1) IFRS 10 IFRS 12 IAS 27 (1) IFRS 9 (4) IFRS 14 (3) 21 (1) (2) (2) (1) (2) (3) (4) 3 (a) (i)
72 70 3 (a) (ii) (iii) , ,000
73 71 3 (a) (iv) , ,000 11,400,000 26,923,000 (b) 26 51,508 37,815 88,870 70, % 53.6%
74 72 3 (c) 4 2 (a) (b)
75 73 4 (c) 16 2(l) (d) (e) (f) (g) (i) (ii) (i) (ii) 6(b) IFRS 3 NSP IFRS 3
76 ,470 15,452 29,500 6,915 45,970 22,367 (40) ,930 22, , EBIT/(LBIT) 10
77 75 5 3,985 29, ,562 45,970 45,970 EBIT/(LBIT) 806 6,495 (80) (486) 6,735 (6,568) ,702 (8,765) 10,937 10,937 20,517 (2,239) (68) (484) 17,726 (6,171) 11, ,299 1, , , , ,271 50,272 1,768 8, ,623 27, ,736
78 (41) (40) (40) LBIT (1,141) (837) (1,978) (1,978) (1,141) (837) (1,978) (1,978)
79 77 5 5,277 6, ,388 22,367 22,367 EBIT/(LBIT) 432 2,624 (400) (901) 1,755 (6,253) (4,498) , ,147 17,147 17,572 2,792 (397) (900) 19,067 (6,030) 13, ,160 4, , , , , ,466 87,933 45,608 2,137 7, ,309 14, ,792
80 78 5 (783) LBIT (3,273) (3,201) (747) (7,221) (7,221) (3,273) (3,201) (747) (7,221) (7,221) ,568 1,931 1, , , ,000 EBIT EBIT 6,735 1,755 (6,568) (6,253) ,937 17,147 (1,485) (1,160) 10,070 11,877 6,823,0005,104,0001, ,000144,000
81 79 6 (a) , (69) (12) 27 1,152 1,603 1,871 6 (b) Hutchison MediPharma (Hong Kong) Limited Nestlé S.A. Nutrition Science Partners LimitedNSP NSP 4(g)NSP 50% NSP18,524,000 NSP NSP NSP ,823 9, , ,475 5, ,517 14,675 88,000 41,00022,000
82 ,485 1, , (136) 880 1,050 1,116 (a) (b) 15% 25%
83 81 9 (c) 10,070 11,877 5,115 1,750 (4,453) (5,044) 817 3,774 (1,677) 1,029 1, (369) 1,050 1, %14.7% 10.4%9.4%
84 (31) 896 (1,947) (8,117) (1,978) (7,221) (1,978) (7,221) (1,239) (893) 4 1,026 (1,239) (40) (31) , , , ,202
85 83 11 (a) 52,050,988 51,918,898-7,323 9,472 - (1,408) (5,834) 5,915 3, (0.0271) (0.1123) (b) 52,050,988 51,918, , ,464 52,878,426 52,650,362-7,323 9,472 - (1,408) (5,834) 5,915 3,
86 84 11 (b) ,381 1, ,704 1, ,953 10,818 1,793 1,547 1,414 1, ,517 14,675 5,256,0002,418,000
87 ,955 4,218 13,061 14, ,509 (20,483) (1,751) (12,983) (5,356) (860) (41,433) 2,472 2, ,059 14, ,211 1,230 2,500 (18) (148) (166) 2,551 2, ,421 1,248 16,888 9,916 3,778 8,141 10,826 32,661 (9,291) (1,476) (8,081) (3,081) (21,929) 625 2, ,745 10, (17) (131) (148) 761 2, ,647 11,860 1, ,774 1,248 5,028
88 ,479 5,293 12,014 14,229 1,967 54,982 (19,027) (1,313) (11,931) (4,399) (1,936) (38,606) 2,452 3, , , (1,597) (6) (1,229) (34) (2,866) 2,472 2, ,059 14,076 8,774 5,032 7,619 10,280 31,705 (8,266) (1,343) (7,583) (2,687) (19,879) 508 3, ,593 11, ,210 1,466 (1,541) (1,130) (2,671) 625 2, ,745 10,732 1, ,314 3,344
89 ,706 1, ,761 1, ,508 1, % 11% 5%
90 ,883 50,479 49,522 59, , ,552 40% (i) 50% Nutrition Science Partners Limited 43.88% (ii) NSP (i) 50% 20% (ii) NSP 50% 12.24%
91 89 17 (i) NSP 51,587 38,121 30,331 24,196 17,031 94,110 85,740 44,828 35, , , ,861 75,159 60,121 17,061 30,000 59,446 39,848 35,646 30,203 30,000 30,000 (620) (820) (91,760) (63,472) (38,484) (29,113) (4,604) (91,760) (64,092) (39,304) (29,113) (4,604) (3,180) (3,809) (5,025) (1,853) 110,203 95,808 66,476 59,358 42,457 60,000
92 90 17 (ii) NSP 252, , , ,544 (3,598) (2,671) (2,612) (2,411) 1, (44) (41) (58) 20,386 19,420 26,620 20,931 (17,543) (3,408) (2,823) (4,196) (3,267) 16,978 16,597 22,424 17,664 (17,543) 3, ,857 17,495 23,272 18,098 (17,543) 6,462 6,256 16,154 3,110 15,00032,000 24,00035,000
93 91 17 (iii) NSP 95,808 84,569 59,358 44,370 60,000 60,000 16,978 16,597 22,424 17,664 (17,543) (6,462) (6,256) (16,154) (3,110) 3, ,203 95,808 66,476 59,358 42,457 60,000 50% 55,102 47,904 33,238 29,679 21,229 30,000 3,282 3,180 (1,700) (1,450) 53,402 46,454 36,520 32,859 21,229 30, ,000239,000 1, ,
94 (2,397) (2,528) (2,112) (2,248) (2,248) (1,368) 136 (769) (111) (2,112) (2,248) 22,384,000 24,124,000 68,206 64,385 10,590 8,437 9,323 10, ,470 10,281 1,272 95, ,872
95 ,102 1,420 1, ,424 6, ,986 2,751 13,410 9,508 1,554 1, ,670 1,554 1,670,0001,554,000
96 ,703,0004,797,000 1, ,608 3,035 3,703 4, ,946 13,948 (a) 25,917 16,819 46,863 30,767 12,203 4,163 (b) 32,139 22, ,651 2, ,384 46,863 30,767 (a) % 2.7% (b)
97 95 22 (a) 1 75,000,000 75,000 51,743,153 51, , ,048,448 52,048 52,048,448 52,048 3, ,051,448 52, , ,108 53,650 8,325 3,
98 96 22 (b) (i) 4.4% (i) AIM ,182 (iii) ,038 (i) AIM ,818 (ii) ,808 (iv) ,857 (iii) ,628 (iii) ,600 (iii) ,000 (iii) ,386 2,303,317
99 97 22 (b) (i) ,459, ,765, , (3,000) 1.32 (305,295) 4.97 (50,000) ,303, ,459,931 (i) AIM 50% 25% (ii) (iii) 25% (iv) (v) 2,303, ,000 1,444,000 (iii) 206,000416,000
100 98 22 (b) (i) (i (v) 38.8% 38.8% 40.0% 35.0% 49.9% 48.43% 46.6% 36.00% 4.540% 4.766% 5.098% 4.700% 3.340% 3.360% 3.130% 3.160% % 0% 0% 0% 0% 0% 0% 0% (i) (ii) (iii) (iv) (v)
101 99 22 (b) (ii) Hutchison MediPharma Holdings Limited 1.8% 25% (i) ,000 (i) ,000 (i) ,000 (i) ,000 (i) , ,420
102 (b) (ii) ,144, ,050, ,120 (ii) 1.80 (2,606,085) 1.61 (1,205,222) , ,144,505 (i) 25% (ii) 2,606,085(i) 2,485,189 (ii) 120,896 (iii) 538,420 79,000 (i) 151,000336,00044,000
103 (b) (ii) % 53% 54% 49% 55% 3.293% 2.564% 2.772% 2.007% 2.439% % 0% 0% 0% 0%
104 ,966,00011,620,000 10,587,000 9,260,000 Hutchison BYS (Guangzhou) Holding Limited3,626,000 1,753,0002,360,000 20% (i) 12.24% (ii) 50% (i) 5 4 (ii) ,215 14,468 8,230 7,944 53,335 46,387 28,104 35, (1,060) (879) (19,928) (18,640) (4,734) (3,300) (3,265) (2,980) (12,466) (9,600) (9,600) 49,182 42,536 29,391 18,484 (6,059) (4,892)
105 ,500 6,915 10,157 8,290 8,286 8,076 (2,238) 2,791 (1,215) (3,977) (446) (503) (21) 7,840 7,573 (2,259) 2,791 (1,215) (3,977) 1, (398) 9,192 7,861 (1,964) 2,941 (1,167) (4,375) ,141,0003,277, ,903 (136) (2,457) 3, ,428 (136) 8 8,227 4, ,969 4,525 30
106 ,811 1, ,352 1,675 4,163 3, ,327 2,893 3,047 1,263 3,895 4,728 12,269 8, ,872 1,783 4,551 3,120 6,345 15,389 15,229 2,
107 (i) 26,923 (i) (ii) 51,508 10,892 51,508 37, % 1.87% (i) 26,923,000 (ii) (a) 51,508 10,892 26,923 51,508 37,815
108 (b) 48,718 37,179 2, ,508 37, ,390,029 2, ,815, (a) 1,2474,574, %87.76%
109 ,042 3,540 1,050 1, , , (11,476) (1,152) (451) (388) (10,937) (17,147) 1,485 1, (27) 287 (19,469) - (55) (3,944) 2,588 - (1,773) (89) - (614) (188) - (88) (1,758) ,317 - (4,551) - 1, (86) (4,065) (18,123) - - (2,826) (17,230) (1,239) (893) (4,065) (18,123)
110 (a) 459 (b) ,654 1, ,888 2,213
111 (a) 7,803 6,967 3,612 6,304 4,
112 (b) 20 (i) 2,986 2, (i) 2,352 1,675 (i) 88 (i) 89 (i) 1,808 1,194 1,985 1,194 (iii) 7,374 6,217 (i) 86 7,374 6,303 (ii) 5,379 5,379 (i) (ii) (iii) 31 Hutchison Healthcare Holdings Limited
113 % 100% 207,460,000 37,500, % 100% 1,000,000 50% 50% 1 100% 100% 3,000,000 50% 50% 50% 50% 229,000,000 Nutrition Science 20, % 50% Partners Limited 40% 40% 200,000,000
114 112 AIM HCM P.O. Box 309, Ugland House Grand Cayman, KY Cayman Islands Computershare Investor Services PLC The Pavilions Bridgwater Road Bristol BS99 6ZY United Kingdom +44 (0) (0) Computershare Investor Services (Jersey) Limited Queensway House Hilgrove Street, St. Helier Jersey, Channel Islands JE1 1ES +44 (0) (0) (a) (b)
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2018 Hope Education Group Co., Ltd
2018 Hope Education Group Co., Ltd. 2018 7 14 2018 8 3 1 2018 Hope Education Group Co., Ltd. 2018 7 14 2018 8 3 2 2018 Hope Education Group Co., Ltd. 2018 7 14 2018 8 3 1 Hope Education Group Co., Ltd.
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0151 2011 6 30 6 30 2011 2010 % 1,279,454 1,002,392 +27.6 421,920 381,658 +10.5 203,595 195,451 +4.2 1 239,122 224,216 +6.6 167,018 161,259 +3.6 % % 33.0 38.1-5.1 15.9 19.5-3.6 13.1 16.1-3.0 15.3 16.6-1.3
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CNQC INTERNATIONAL HOLDINGS LIMITED 1240 2 3 4 11,053,456 7,302,293 5 (9,247,614) (6,227,767) 1,805,842 1,074,526 9,598 3,763 4,228 1,504 5 (165,624) (123,375) 5 (552,981) (389,389) 1,101,063 567,029 5,681
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2014 2 3 7 11 14 23 30 32 34 35 37 38 39 114 1 2005 Cricket Square, Hutchins Drive P.O. Box 2681 GT, Grand Cayman KY1-1111, Cayman Islands 18 49 4902-03 Royal Bank of Canada Trust Company (Cayman) Limited
20,232,000 4,310,000 0.33 20,232,000 19,134,000 5.7% 4,310,000 5,184,000 2014/15 2 100% 5.7% 20,232,000 19,134,000 3 2014/15 20,232,000 19,134,000 5.7% 14,351,000 13,032,000 16,783,000 16,326,000 4,310,000
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Kingsoft Corporation Limited 03888 KINGSOFT CLOUD 2013 2 278 78 48 183 17M 2013 2 7 ......................................................................... 1 3 1..................................................................
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Boyaa Interactive International Limited 0434 238 1 2 12 15 183 17M 48 ... 1... 3... 4... 5... 7... 8... 8... 8... 8... 9... 12 i 238 1 2 12 15 1 5 571 0.00005 6 2 Boyaa Interactive International Limited
2016 2 3 6 14 15 21 31 33 35 36 37 39 103 104 1 2016 * * * * 168 200 14 1407 http://arttextile.etnet.com.hk Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1 1111 Cayman Islands Royal Bank of
,787,321 6,292,569 (3,178,103) (3,422,560) 2,609,218 2,870, ,824 85,775 (1,766,182) (2,108,497) (477,730) (536,273) (79,000) (98,0
Bosideng International Holdings Limited 3998 3 31 8.0% 5,787.3 0.5 45.1% 112.5% 280.9 708.7 2.6 3 313 31 1 3 31 3 31 3 5,787,321 6,292,569 (3,178,103) (3,422,560) 2,609,218 2,870,009 4 55,824 85,775 (1,766,182)
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Overseas Chinese Town (Asia) Holdings Limited 03366 ... 1.... 4... 16... 19.... 143... 174... 180 i (i) (ii) 1 2 4 56 03366 1 2048 S 144A 73,371,900 Credit Suisse (Hong Kong) Limited 2 Pacific Climax Pacific
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Keen Ocean International Holding Limited 1. Keen Ocean International Holding Limited 2. Codan Trust Company (Cayman) Limited Cricket Square, Hutchins Drive, PO Box 2681, Grand Cayman, KY1-1111, Cayman
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GREAT WORLD COMPANY HOLDINGS LTD 8003 353 36 54 55 48 183 17M http://www.hkgem.com http://www.gwchl.com i ..................................................................... 1...............................................................
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此 乃 要 件 請 即 處 理 閣 下 對 本 通 函 任 何 方 面 或 對 應 採 取 之 行 動 如 有 任 何 疑 問, 應 諮 詢 閣 下 之 註 冊 證 券 商 銀 行 經 理 律 師 專 業 會 計 師 或 其 他 專 業 顧 問 閣 下 如 已 售 出 或 轉 讓 名 下 全 部 康 哲 藥 業 控 股 有 限 公 司 股 份, 應 立 即 將 本 通 函 送 交 買 主 或 承 讓
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Reach New Holdings Limited () : 8471 2017 GEM GEM GEM GEM GEM GEM GEM GEM GEM 1 2017 2 3 4 10 11 14 15 24 25 34 35 38 39 40 41 42 43 44 79 80 PO Box 1350 Clifton House 75 Fort Street Grand Cayman KY1 1108
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RICI HEALTHCARE HOLDINGS LIMITED : 1526 2016 2 6 8 9 10 12 16 28 48 67 81 88 2017 2017 6 2 2016 6 23 2015 5 20 2014 7 11 2013 11 6 500 2 2014 7 11 (i)(ii) 2015 2 16 2015 6 29 3 2016 10 6 2016 10 6 2008
40% 6 1920 21 22 40 138 15 N-1 N-3 (http://www.hkexnews.hk) (http://www.tfkf.com.hk) 183 22 .................................................................. 1............................................................
5 25,347 26,359 (9,642) (12,913) 15,705 13, ,951 3,954 (8,797) (43,127) 7 (53,776) (1,409) (6,837) (80,268) (84,388) 8 (12,581) (13,316) (31) 9
China Vanguard You Champion Holdings Limited ( ) GEMGEM GEM GEM GEM GEM GEM GEM GEM GEM 1 5 25,347 26,359 (9,642) (12,913) 15,705 13,446 6 13,951 3,954 (8,797) (43,127) 7 (53,776) (1,409) (6,837) (80,268)
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Modern Education Group Limited 1082 20121231 20121231 128,180,0002011167,060,00023.27% 4,050,000201110,590,00061.74% 2012123120110.025 20121231 2011 1 1231 2012 2011 4 128,176 167,056 5 21,555 1,050 7
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此乃要件 請即處理 閣下如對本通函任何方面或應採取的行動有任何疑問 應諮詢 閣下的股票經紀 其他持牌證 券商 銀行經理 律師 專業會計師或其他專業顧問 閣下如已售出或轉讓名下所有金嗓子控股集團有限公司的股份 應立即將本通函連同隨附的代 表委任表格送交買主或承讓人 或經手買賣的銀行 股票經紀或其他代理人 以便轉交買主或 承讓人 香 交易及結算所有限公司及香 聯合交易所有限公司對本通函的內容概不負責 對其準確性
EJE (HONG KONG) HOLDINGS LIMITED * 8101 GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM (1) (2) * 1
EJE (HONG KONG) HOLDINGS LIMITED * 8101 GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM (1) (2) * 1 5 132,409 135,524 (90,801) (98,470) 41,608 37,054 5 1,905 1,674 (10,460) (8,142) (45,962) (40,726) (4,919)
企 業 簡 介.......................................................................... 2 公 司 資 料...........................................................
Intime Retail (Group) Company Limited ( ) : 1833 2013 企 業 簡 介.......................................................................... 2 公 司 資 料..........................................................................
4 37,919 40,859 6 (1,752) (10,323) 36,167 30,536 35,919 30, (430) 36,167 30,
RIVERINE CHINA HOLDINGS LIMITED 1417 2017 12 31 2017 12 31 2016 12 31 2017 12 31 3(a) 363,303 309,268 4(a) (296,434) (248,625) 66,869 60,643 3(b) 7,611 10,283 (4,682) (4,188) (42,690) (31,267) 5 (1,496)
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SHIFANG HOLDING LIMITED 1831 1 19,125 20,443 1,266 1,500 4 5 27,013 22,907 47,404 44,850 6,472 5,583 50,511 51,527 6 101,021 7 10,314 9,714 5 4,390 5,382 220 522 117,729 109,492 290,657 182,220 338,061
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China Resources Healthcare Group Limited Phoenix Healthcare Group Co. Ltd 1515 (1) (2) (3) (4) (5) (6) 9 55 56 57 58 132 2016 10 31 6 E-825 301 304 183 17M 48 2016 10 7 ... 1... 9... 56... 58... 133...
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1. 2. Codan Trust Company (Cayman) Limited Cricket Square, Hutchins Drive, PO Box 2681, Grand Cayman, KY1-1111, Cayman Islands 3. (a) (b) 4. 27(2) 5. 6. 7. 8. 0.01 10,000,000,000 0.01 9. A 1 2 3 4-7 8-9
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: 01250 Beijing Enterprises Clean Energy Group Limited 2015 2 3 5 10 11 12 13 14 15 24 28 01 2015 Clifton House 75 Fort Street, PO Box 1350 Grand Cayman, KY1-1108 Cayman Islands 18 67 6706-07 Appleby Trust
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2 3 9 12 14 16 17 18 2 * 183 17 1712-1716 Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands 1 A 30 B&C www.inspur.com.hk 596 * Royal Bank of Canada Trust Company (Cayman)
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KINGWELL GROUP LIMITED 1195 413 70 B1B68 18317M 48 ...................................................... 1................................................. 4.................................. 14...............................
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CHINA HUIYUAN JUICE GROUP LIMITED 1886 4 8 9 10 20 21 22 48 * ......................................................................... 1...................................................................
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TIANNENG POWER INTERNATIONAL LIMITED 00819 18 1518 48 18 15 18 5A 20% 15 18 1 5B 10% 571 0.1 2 TIANNENG POWER INTERNATIONAL LIMITED 00819 Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111
KPa-BM Holdings Limited * 2663 (I) (II) (III) *
KPa-BM Holdings Limited * 2663 (I) (II) (III) 5 17 627 42 43 48 183 22 * ... 1... 5... 18... 19... 37... 42 6 27 1 5711 6 BUILDMAX HOLDINGS LIMITED 2 25% 10,000 571 0.01 60.0% 40.0% 1508 26.7%26.7%26.7%
1 2 4 5 16 21 23 24 25 26 27 28 1 CA Cricket Square Hutchins Drive PO Box 2681 Grand Cayman KY1-1111 Cayman Islands 43 19 10 1009 Butterfield Fulcrum Group (Cayman) Limited Butterfield House 68 Fort Street
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SINO BIOPHARMACEUTICAL LIMITED : 1177 2017 1 1177 www.sinobiopharm.com FCCA,CPA 166 1 43 SMP Partners (Cayman) Limited Royal Bank House 3rd Floor, 24 Shedden Road P.O. Box 1586 Grand Cayman KY1-1110 Cayman
2 4 7 8 9 10 21 26 36 50 52 53 55 56 58
2 4 7 8 9 10 21 26 36 50 52 53 55 56 58 (ACCA, HKICPA) Clifton House 75 Fort Street P.O. Box 1350 Grand Cayman KY1-1108 Cayman Islands 465 103 www.chinauton.com 23 24 2404 2014 2 26 33 Appleby Trust (Cayman)
Shineroad International Holdings Limited 1587 6 17 18 19 20 35 291103 06 43 44 (www.hkexnews.hk) (www.shineroad.com) 48 18322 ...................................................................... 1...............................................................
3 51,115,551 37,662,173 14,041,946 14,048,008 (12,294,931) (13,969,624) (4,241,232) (5,114,524) 38,820,620 23,692,549 9,800,714 8,933,484 3,648,828 52
Link Holdings Limited * 8237 GEM GEM GEM GEM GEM GEM GEM * 1 3 51,115,551 37,662,173 14,041,946 14,048,008 (12,294,931) (13,969,624) (4,241,232) (5,114,524) 38,820,620 23,692,549 9,800,714 8,933,484 3,648,828
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COUNTRY GARDEN HOLDINGS COMPANY LIMITED 2007 2015 5 20 10 88 JW 3(1-4) 19 23 48 183 22 2015 4 14 ... 1 1.... 4 2.... 4 3.... 4 4.... 5 5.... 5 6.... 5 7.... 6 8.... 6 9.... 6... 7... 11... 19 i 2015 5
... 2... 3... 5... 6... 8... 13... 19.... 26... 41... 60... 62... 63... 64... 66... 68.... 71 1 2015
2015 Intime Retail (Group) Company Limited () : 1833 ... 2... 3... 5... 6... 8... 13... 19.... 26... 41... 60... 62... 63... 64... 66... 68.... 71 1 2015 2006 11 8 2007 3 20 199817 29172,895,674 201061
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年報 (1) (2) (3) 2 3 4 7 10 13 21 32 34 35 36 37 38 39 CPA CPA 28 29 PO Box 309 Ugland House Grand Cayman KY1-1104 Cayman Islands 168 200 21 2115 2116 Royal Bank of Canada Trust Company (Cayman) Limited
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CK ASSET HOLDINGS LIMITED Cheung Kong Property Holdings Limited 826 2728 2948 20 5758 482 7 ................................................................. 1...........................................................
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CHINA METAL INTERNATIONAL HOLDINGS INC. 319 1 2 1 1316 183 46 48 .................................................... ii........................................................ 1....................................................
,801,000 1,473,691 20,764 12,778 (548,084) (452,982) (483,269) (395,241) (97,289) (66,548) (278,473) (209,777) (85,45
Tsui Wah Holdings Limited 1314 2015 3 31 3 31 2015 2014 1,801,000 1,473,691 22.2% # 1,266,388 1,105,011 14.6% 522,188 355,412 46.9% ## 12,424 13,268 (6.4%) 157,591 156,043 1.0% 157,407 156,031 0.9% 184
02 04 05 07 15 17 18 19 20 41 43 02 GBS, OBE, JP GBS, OBE, JP Conyers Dill & Pearman GBS, OBE, JP GBS, OBE, JP Butterfield Fund Services (Cayman) Limited Butterfield House 68 Fort Street P.O. Box 705,
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2 3 4 7 14 18 20 29 30 31 32 33 34 72 1 , FCPA, FCCA, ACIS ACS, FCPA, FCCA, ACIS ACS 4th Floor P.O. Box 2804 George Town Grand Cayman Cayman Islands 18 28 2805 Butterfield Fund Services (Cayman) Limited
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WAI CHI HOLDINGS COMPANY LIMITED 1305 11 17 21 183 22 ................................................................ 1 1....................................................... 4 2..................................................
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VITAR INTERNATIONAL HOLDINGS LIMITED 195 3 6 1 2607 13 16 48 28 26 .................................................................... 1 2..............................................................
2 4 7 23 30 44 55 57 58 60 61 63 136 137 Huang James Chih-Cheng Huang James Chih-Cheng Appleby Trust (Cayman) Ltd. Clifton House 75 Fort Street P.O. Box 1350 Grand Cayman KY1-1108 Cayman Islands 88 1306
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2 3 6 13 17 25 31 44 48 49 51 52 54 116 1 Cricket Square, Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands B 9-A 1 36 SMP Partners (Cayman) Limited 3rd Floor, Royal Bank House 24 Shedden
Cricket Square Hutchins Drive, P.O. Box 2681 Grand Cayman KY Cayman Islands SMP Partners (Cayman) Limite
1 3 10 17 19 20 22 23 24 2018 9 5 2018 8 9 Cricket Square Hutchins Drive, P.O. Box 2681 Grand Cayman KY1 1111 Cayman Islands 25 22 2207 25 22 2207 SMP Partners (Cayman) Limited Royal Bank House 3rd Floor,
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Sun International Group Limited 8029 10% 22-2622 15 19 28 26 www.hkgem.com i ............................................................. 1........................................................ 3....................................................
2 4 6 20 27 46 57 59 60 62 63 65 150 151 Huang James Chih-Cheng Huang James Chih-Cheng Appleby Trust (Cayman) Ltd. Clifton House 75 Fort Street P.O. Box 1350 Grand Cayman KY1-1108 Cayman Islands 88 1306