untitled
|
|
|
- 得 充
- 7 years ago
- Views:
Transcription
1
2 , BSc, ACGI, MBA, BSc, MBA, BEc, CA, BA, BA, LLL, JD, BSE, MA, MA, EdM, Solicitor, FCIS, FCS(PE), BSc, MBA, ACGI, MA, MBA, HonFCGI, BA, BMBCh, PhD, DM, DSc, FSB Panmure Gordon (UK) Limited Panmure Gordon (UK) Limited UBS Limited
3 *
4 2
5 3 100% 9,1804, ,110 4,6907,700 9,900 2,4802,950 AstraZeneca AB (Publ) ,4803,010 AZD b c-met AZD6094 c-met Fruquintinibb b Sulfatinib 32% b HMPL-523 Syk HMPL-523
6 4 - HMPL ,400 AZD6094 EGFR epitinib theliatinib b PI3Kδ HMPL-689FGFRHMPL % % 9,990 19% % 2,260 1,860-6% 1,3201, Earth s Best The Hain Celestial Group, Inc. HAINHain Celestial
7 5 (1) (2) Hain Celestial
8 6 +100% ,280 4,480 FDA AZD % % 1411,472
9 7 GMP 42 3, ,500 8 Hain Celestial 11,400 5,1104, ,030 5,320 (1) 2,630 (2) 2, Nutrition Science Partners LimitedNSP 7,700 9,900 2, ,380
10 8 100% 9,1804,600 5, , % 2, % , Hain Celestial %
11 9 710BT (b) HMPL-004 Anti-TNFα VEGF 1/2/ AZD6094 HMPL-523 VEGFR/FGFR EGFRm+ EGFR WT c-met Syk 2 EGFR 1 EGFR + AZD9291 EGFR + EGFR + c-met c-met c-met c-met c-met BT BT BT BT BT BT BT BT BT BT HMPL-689 HMPL-453 PI3Kδ FGFR
12 bpoc 10 1, % % HER2 trastuzumab FDA VEGF/VEGFR EGFR bevacizumab 71
13 ,730 gefitinib NSCLCEGFR 16,580rituximab TKIs VEGFR EGFR AbI c-met PI3K Syk FGFR TKI 24.8% 30.5% 19.7% 74 8% 23% 17 4% pemextredcapecitabine gemcitabine20% paclitaxel docetaxel 20% DNA oxaplatintemozolomide nedaplatin 11% letrozole bicalutamideanastrozole 6%
14 12 (1) AZD6094 c-methmpl-523 SykHMPL-453 FGFR (2) VEGFR EGFRHMPL-689 PI3Kδ (3)HMPL- 004 TNFα IL1-β NSP b PoC PoC PoC FDA ABTPAABTPA FDA (1) (2) (3) FDA ABTPA AZD6094 b PoC AZD6094HMPL-004 7,700 NSP 50/ AZD6094 HMPL ,4802,950 NSP NSP 7 4,480 3,010 PRCC AZD ,190 Hutchison MediPharma Holdings Limited 12.2% NSP 500
15 13 FTE NSP AZD6094 1, b FGFR HMPL-453 Syk HMPL-523 PI3Kδ HMPL-689 AZD6094 HMPL-504/volitinib / savolitinibazd6094 c-met c-met HGFR c-met c-met AZD6094 c-met c-met c-metc-met+ PRCC PRCC c-met 1~20% PRCC 40~75% AZD6094 c-met PRCC >30%) AZD6094 c-met c-met PRCCAZD c-metc-met O/E 40~92% c-metazd6094 c-met AZD c-met AZD6094 c-met c-met 1 PRCC27 PRCC 10~15% PRCC ASCO c-met AZD PRCC AZD PR>30% 1 AZD % 3SD 8 AZD6094PRCC ORR 38% PRCCORR 13.5% foretinib PRCC 74 AZD6094 PRCC ORR FDA AZD6094c-Met PRCC 5
16 NSCLCc-Met EGFR-TKI 140 NSCLC NSCLC 30% EGFR EGFRm+EGFREGFR- TKI EGFRm+ NSCLC 20 EGFR-TKI EGFR T790Mc-Met 45-50%15-20% erlotinib EGFRm+ EGFR-TKI EGFR-TKI AZD9291 FDA NSCLC T790MEGFR-TKI AZD9291 ORR64% %c-MetEGFR-TKI AZD9291AZD6094 EGFR-TKI 60-70% EGFRm+ c-met FDA ORR AZD c-met T790MEGFR-TKI NSCLC 10 4 EGFR c-met NSCLC 140 NSCLC 67% c-met 5 6 c-met %c-Met 40%c-Met 7 8 c-met AZD6094 c-met AZD6094 8AZD6094 c-met HMPL-504 volitinib 504 volitinib WHO INN volitinib INN savolitinib VEGF/VEGFR VEGF VEGFR
17 15 VEGF/ VEGFR TKI sorafenib sunitinib 1012 bevacizumab 71 VEGFR HMPL- 013 VEGFR VEGFR VEGFR 1, 2, 3 VEGFR b b 42 5 ORR 10.3% DCR 82.1% 9 OS 62% regoratenib 160 (n=136) ORR 4.4% DCR 51.5% 9 OS46%n=68ORR 0.0% DCR 7.4% 9OS24% b 11.9% 48.5% 71 = 2 1
18 16 b 420 VEGFR b PoC 18 IAS PoC (b) [1] Stivarga (b) 5 3/1 3 N = /1 N = 136 N = % 82.1% 66.7% 62% 4.4% 51.5% ~38% ~46% 0% 7.4% ~3% ~24% [1] = >30% = <20% =16 <20% = 9
19 17 2 NSCLC 80 NSCLC NSCLC NSCLC 90 NSCLC = 2 1 bevacizumab VEGFRNSCLC ramcirumab lenvatinib a 6 NSCLC 4 NSCLC NSCLC b 1 GMP VEGFR VEGFR FGFR VEGFR FGFR 3 50
20 18 NET octreotide/ everolimus/ sunitinib/ lanreotide/ NET (Ki67<10%) NET 15.6 / / / 5.5 NR / p <0.001 <0.001 < % / 2% 5% / 2% 9% / 0% NR 32% 67% / 37% 73% / 51% 63% / 60% NR 100% 12,000-15, everolimus 5% ORR10% DCR 70%octreotide 6% 35-45%lanreotide FDA Ki67 10% 0% 32% % 100% b / bb FDA b
21 19 FDA EGFR EGFR EGFR EGFR EGFR EGFR gefitinib erlotinib c-met c-met EGFR EGFR 53% 66-90% EGFREGFR 10 EGFR EGFR (1) EGFR (2) EGFR EGFR EGFR c-met EGFR EGFREGFR+ EGFREGFR O/E EGFR 10-30% EGFR EGFR EGFR EGFR EGFR 614 EGFR 27-54%EGFR EGFR EGFR EGFR 18 EGFR 62% 30-90%44-52%20-48%54-66%9-62% 68% EGFR HMPL-813 EGFR EGFR EGFR EGFR
22 b EGFR 10% 80% b b HMPL-309 EGFREGFR EGFR EGFR 60 EGFR 24 EGFR EGFR EGFR 90 T 120 RPTD b EGFREGFR HMPL-523 HMPL-004 HMPL- 523 Syk B HMPL-004 IBD HMPL-523 HMPL-523 Syk Syk T T B B B Syk Rigel Syk fostamatinib Syk R406 Syk Syk Syk
23 21 HMPL-523Syk IC 50( )* R788 R406 Rigel/ Syk, FLT-3, KDR, Src, Lyn, JAK rcia: 10/BID msle: 10/BID CLL: 80// 3 100BID 150QD 2ITP GS-9973 (Gilead) 55 * Syk 1NHL, CLL HMPL Syk rcia (QD) ED min = 0.7-1/ ED 50 = 1.4-2/ 1 Syk [1] Naive ph2.1 HCI HMPL- 523Syk Syk HMPL-523 HMPL MPK, QOD IP 10 MPK, BID, PO HMPL-523 (MPK, QD, PO) Enbrel R406 9 [1]MPK =QD = BID =QOD =PO = IP = Naïve = Fostamatinib Syk R406Enbrel TNF 46
24 22 [1] 1,800 HMPL [2] 1/3 HMPL-004 HMPL-004 NSP HMPL HMPL-004 HMPL-004 HMPL b HMPL-004 NSP NATRUL-3 HMPL HMPL-004 HMPL-004 NATRUL-3 NATRUL % b 2,400 HMPL NATRUL-3 5-
25 23 HMPL-004 2, b NATRUL % HMPL-004 2, % NATRUL NATRUL-3 HMPL-004 b NATRUL-3 NSP HMPL
26 24 HMPL-689 Gilead Sciences idelalisib PI3Kδ B PI3Kδ Infinityduvelisib PI3Kδ Bibrutinib ibrutinib BTK B HMPL-689 PI3K duvelisib PI3Kγ(gamma) HMPL-689 Idelalisib 150 HMPL-689 HMPL-689 P450 HMPL-689 idelalisib duvelisib IC 50 HMPL-689 Idelalisib Duvelisib PI3Kδ (n = 3) PI3Kγ (vs. PI3K δ) (142X) PI3Kα (vs. PI3K δ) >1 (>1,250X) PI3Kβ (vs. PI3Kδ) HMPL-453 FGFRHMPL (109X) (52X) (433X) (147X) (2X) (143X) (8X) HMPL- 523 HMPL-523 SykHMPL-079 Syk HMPL-689 idelalisib duvelisib Syk HMPL-523 Syk B
27 25 29% % % 9,9905,160 21% 2,2601,860 (i) %(ii) %(iii) 51% %(iv) % 20% 141 1,472 34%
28 % 5.6% 17.4% (1) (2) (3) (4) (5) - 12% %
29 % % 13.4% 16% 12% % 1,380 1,240 1,700 1,600 13,500 13,000 GMP 12 78, GMP
30 28 3,000 1,500 3, , % 3, ,500
31 29 19% % % 7% 6% 7,630 7, , % 5,560 H7N H3N % 4,140 3,050 13% 1,830 1,630 45% 1,470 1, ,3401,020
32 30 GMP 9 230,000 GMP 40 66, ,550-51% 49% 5, % 240 (1) 5.3 (2) 14 (3) 25% 60%
33 31 50% % 80% % [2] 50% % [1] 294 1,700 GSP [1] 50 GSP [1] 600 1, [1] GSP[2]
34 32-9% % , , % DHA omega-3 86,100 59,400 26, , , ,
35 33 6% 1,320 1, Hain Celestial Hain Celestial 14% 1,150 1,020 Earth s Best 125% % % % % % 1060 Earth s Best Earth s Best 250Hain Celestial Earth s Best
36 34 PoC b AZD6094 PRCC c-met bhmpl-523 b PoC HMPL-689 (PI3Kδ) HMPL-453 (FGFR) HMPL-004 Earth s Best
37 Hutchison MediPharma (Hong Kong) Limited Sen Medicine Company Limited
38 Hutchison Whampoa Japan K.K Hutchison Whampoa Europe Investments S.à r.l. (ITU) GSMA Limited Transport Initiatives Edinburgh Ltd. FPT Group Limited Railtrack Group plc Biological Reviews the Journal of Physiology Europace (BA) (BMBCh) (PhD) (DM) (DSc) (FSB) 56 Tempus Energy Limited GKN Evo edrive Systems Ltd Gasrec Limited NTR plc Current OpenGrid Limited Global Crossing Ltd. North West Water International Ltd. S.G. Warburg and Co. Ltd.
39
40 38 91(1) ,088, , ,600 41,000 30,542 20,000 2,475 (i)
41 (1) 768,182 (768,182) (3) 64,038 64, (1) 76,818 (76,818) (2) 26,808 26, (4) 40,857 40, (3) 102,628 (102,628) (3) 177,600 (77,600) 100, (3) 150, , (3) 896,386 (593,686) (5) 302, ,303,317 (1,025,228) (593,686) 684,403 (1) AIM 50% 25% (2) (3) 25% (4) (5) 593,686 (ii) Hutchison MediPharma Holdings Limited Hutchison MediPharma Holdings Limited
42 ,000 (40,000) (17,000) ,000 (30,000) (20,000) ,000 (300,000) (1) 25,000 (10,000) (10,000) 5, (2) 106,420 (924) (86,096) 19, (3) 1,187,372 1,187, ,420 1,187,372 (80,924) (433,096) (4) 1,211,772 (1) (2) 25% (3) 25% 25% (4) 433,096(a) 39,884(b) 393,212 3% Hutchison Healthcare Holdings Limited (1) HHHL 36,666, % Computershare Company Nominees Limited (2) CCNL 16,331, % (3) 2,640, % Slater Investments Limited (3) 2,263, % (1) HHHLHHHL (2) CCNL SC (3)
43 41 4th Floor, Hutchison House, 5 Hester Road, Battersea, London
44 42 AIM ( (
45 43 100% 4/4 4/4 4/4 4/4 4/4 4/4 4/4 4/4 4/4
46 44 AIMAIM AIM AIM 51
47 45 100% 3/3 3/3 3/3
48 46
49 47
50 48 AIM 100%
51 49 19,503 (1) (4) 19, ,888 (2) (4) 615,385 14,810 24,000 (5) 1,003, ,551 (2) 217,949 21,482 (5) 512,982 19,503 (3) 19,503 19,503 (1) 19,503 19,503 (3) (4) 19,503 51,488 51,488 51,488 51,488 51,488 51, , ,334 14,810 45,482 1,748,541 (1) (2) 19,503 (3) (4) (5) 100%
52 50 Investor Relations 4th Floor, Hutchison House, 5 Hester Road, Battersea, London 100% info@chi-med.com
53
54 ,813 45,970 (72,049) (22,208) 19,764 23,762 (4,112) (3,452) (22,572) (21,295) 6 (182) 1, ,202 10, ,100 11,555 8 (1,516) (1,485) 6,584 10,070 9 (1,343) (1,050) 5,241 9, ,034 (1,978) 7,275 7,042 4,357 7,323 1,017 (1,408) 5,374 5, ,901 1,127 7,275 7,042 11(a) (b) (a) (b)
55 53 7,275 7,042 (2,819) 3,342 4,456 10,384 1,825 10,360 1,017 (1,503) 2,842 8,857 1,614 1,527 4,456 10,384
56 ,482 5, ,436 1, , , , , , ,405 1, ,446 14,789 2,563 1, ,591 1, ,125 46,863 94,130 67, , , ,076 52,051 41,813 36,819 94,889 88, ,994 15, , ,836
57 ,427 4, ,638 15, ,716 7, ,282 51, ,185 78, ,947 2, ,923 29,870 2,397 99,055 80,831 24,945 (11,400) 149, , , ,667
58 56 52,048 93,669 4,974 9, (89,989) 70,578 11,620 82,198 5,915 5,915 1,127 7, ,280 2, ,618 2,942 2, ,342 2,942 5,915 8,857 1,527 10,384 23(a) 3 6 (2) (168) (120) (243) 9,459 9,096 3,371 12,467 31(a) (577) (577) 52,051 93,675 5,016 12, (74,447) 88,870 15, ,836
59 57 52,051 93,675 5,016 12, (74,447) 88,870 15, ,836 5,374 5,374 1,901 7,275 (933) (933) (11) (944) (1,599) (1,599) (276) (1,875) (2,532) (2,532) (287) (2,819) (2,532) 5,374 2,842 1,614 4,456 23(a) 1,025 4,598 (2,943) 2,680 2, (182) (b) 7,526 7,526 23(b (ii)) (3) (4) (35) (42) (a) (1,179) (1,179) (234) (234) (234) 3,059 3,059 (2,250) (2,250) 53,076 98,273 2,661 9, (69,185) 94,889 24, ,883
60 58 29(a) (490) (4,065) (1,466) (1,485) (908) (1,181) 15,949 11,308 13,360 5,028 (3,729) (2,500) (5,000) (12,179) 29(b) 689 (20,219) (2,500) 3,059 (2,250) (1,179) (577) 8,205 14,261 (11,277) (568) 121 2,680 7 (641) 13,123 (7,500) 15,651 46,863 30,767 (417) ,946 46,863 38,946 46, , ,125 46,863
61 P.O. Box 309, Ugland House, Grand Cayman, KY1-1104, Cayman Islands AIM 2 IFRS (a) 2(d) (b) 2(a)
62 60 2 (b) (c) (d)
63 61 2 (e) (f) 2(I)
64 62 2 (g) 2(f) (h) (i) (j) (k)
65 63 2 (l) (m) (n) (o) (p) (q)
66 64 2 (r) (s) (i) (ii) (t) (i)
67 65 2 (t) (ii) i)ii) iii) (u) (v) (w)
68 66 2 (x) (y) (i) (ii) (iii) (z)
69 (2) (2) (2) 19 (1) 27 (2) 9 (4) (2) (2) 11 (2) 14 (2) 15 (3) (1) (1) (2) (1) (2) (3) (4)
70 68 3 (a) (i) (ii) 28.5% 30.4%
71 69 3 (a) (iii) , ,000 (iv) ,000 69,000 (b)
72 70 3 (b) 27 53,205 51,508 94,889 88, % 58.0% (c) 4 2
73 71 4 (a)
74 72 4 (b) (c) 16 2(l) (d) (e) (f) 3 29(b)
75 73 5 (i) 66,985 16,470 (ii) 24,828 29,500 91,813 45,970 (40) 91,813 45,930 (i) 6, ,020.0 (ii) , , , (a) EBIT/(LBIT) 10
76 ,832 24, ,936 91,813 91,813 EBIT/(LBIT) 1,156 (2,614) (337) 999 (796) (6,865) (7,661) ,611 (8,409) 15,202 15,202 24,839 (10,990) (329) 1,002 14,522 (6,422) 8, ,410 1, , , , , , , ,767 52,606 1,173 7, ,596 21, ,938
77 75 5 EBIT 2,096 2,096 2,096 2,096 2,096 2,096
78 76 5 3,985 29, ,562 45,970 45,970 EBIT/(LBIT) 806 6,495 (80) (486) 6,735 (6,568) ,702 (8,765) 10,937 10,937 20,517 (2,239) (68) (484) 17,726 (6,171) 11, ,299 1, , , , ,271 50,272 1,768 8, ,623 27, ,736
79 (41) (40) (40) LBIT (1,141) (837) (1,978) (1,978) (1,141) (837) (1,978) (1,978) , ,000628,000 (LBIT)/EBIT (LBIT)/EBIT (796) 6,735 (6,865) (6,568) ,202 10,937 (1,516) (1,485) 6,584 10,070 11,458,000 6,823,000 79,000120,000
80 (480) 1, (281) (69) (182) 1, (i) 62,464 16,823 1, (ii) (ii) ,574 4, ,297 16,517 (i) 6, ,780.0 (ii) 88, ,00041,000
81 (a) 19 31(a) (a) ,516 1, , (136) 1,343 1,050 (a) 16.5% 16.5% (b)
82 80 9 (c) 6,584 10,070 4,464 5,115 (5,620) (4,453) 1, (1,062) (2,673) 1,161 1, ,343 1, % 50.8% 20.4% 10.4%
83 81 10 (i) 2,096 (31) (ii) (1,947) 2,096 (1,978) (62) 2,034 (1,978) 2,515 (1,239) 2,515 (1,239) (i) (40) 2, ,096 (31) (ii)
84 82 11 (a) 52,563,387 52,050,988 4,357 7,323 1,017 (1,408) 5,374 5, (0.0271) (b)
85 83 11 (b) 52,563,387 52,050, , ,438 52,901,145 52,878,426 4,357 7,323 1,017 (1,408) 5,374 5, ,432 1, ,748 1, ,864 12,953 1,370 1,096 3,195 2, ,297 16,517 9,442,0005,256,000
86 ,551 2, ,421 1,248 16,888 (60) (68) (2) (248) (28) (406) 29(b) ,215 2,380 3,729 (21) (388) (409) 1,671 1,097 (2,768) 2,491 4, , , , ,647 11,860 (19) (56) (2) (201) (278) 29(b) ,180 (19) (354) (373) 952 2, ,792 12,501 1,539 1, , ,482
87 ,472 2, ,059 14, ,211 1,230 2,500 (18) (148) (166) 2,551 2, ,421 1,248 16, , ,745 10, (17) (131) (148) 761 2, ,647 11,860 1, ,774 1,248 5,028
88 ,761 1,706 (41) 55 1,720 1, (6) ,436 1, (b) 1,546 1, ,000407,0001,546,000
89 % 5% 20% 11.0% 11.0% 11.6% 5% 5% 5% (b) GSP
90 ,883 61,883 46,131 49,522 31(b) 5, , ,405 40% (i) 50% Nutrition Science Partners Limited 43.79% (ii) NSP (i) 50% 20% (ii) NSP 50% 12.42% 12.24
91 89 18 (i) NSP 51,837 51,587 18,874 30,331 6,249 17,031 92,734 94,110 56,569 44,828 2, , ,697 75,443 75,159 8,548 17,061 73,552 59,446 67,731 35,646 30,000 30,000 (625) (7,476) (820) (10,000) (98,260) (91,760) (44,576) (38,484) (2,902) (4,604) (98,885) (91,760) (52,052) (39,304) (12,902) (4,604) (3,858) (3,180) (19,216) (5,025) 115, ,203 71,906 66,476 25,646 42,457
92 90 18 (ii) NSP 300, , , ,160 (3,645) (3,598) (2,651) (2,612) 1,317 1, (44) 24,553 20,386 31,505 26,620 (16,811) (17,543) (3,735) (3,408) (5,103) (4,196) 20,818 16,978 26,402 22,424 (16,811) (17,543) (2,352) 3,879 (1,895) ,466 20,857 24,507 23,272 (16,811) (17,543) 12,820 6,462 19,077 16,154 5,000 15,000 20,000 24,000
93 91 18 (iii) NSP ,203 95,808 66,476 59,358 42,457 60,000 (469) 20,818 16,978 26,402 22,424 (16,811) (17,543) (12,820) (6,462) (19,077) (16,154) (2,352) 3,879 (1,895) , ,203 71,906 66,476 25,646 42,457 50% 57,690 55,102 35,953 33,238 12,823 21,229 3,205 3,282 5,000 (1,901) (1,700) 55,789 53,402 39,158 36,520 17,823 21, ,000254,000 1,656 1,329 61,170 8,379
94 (2,947) (2,397) (2,690) (2,112) (2,112) (2,248) 29(b) (98) (363) (128) (2,690) (2,112) 7,877,000 9,036,000 23,531 14,855 8,647 10,098 10, ,097 5,672 1,148 1, ,507 41,198
95 , ,405 1, ,524 11,803 31(b) 1,922 2,986 34,446 14,789 3, , ,670 1, (62) 74 1,793 1,670 1,793,0001,670,000
96 ,130,0003,703,000 1, ,106 1,608 2,130 3, ,019 20,946 (a) 6,927 25,917 (a) 12,179 51,125 46,863 8,104 12,203 (b) 40,213 32, ,543 1, ,125 46,863 (a) % 2.1% (b)
97 95 23 (a) 1 75,000,000 75,000 52,048,448 52,048 3, ,051,448 52,051 52,051,448 52,051 1,025,228 1,025 53,076,676 53, , ,182 76, ,628 77, ,
98 96 23 (b) (i) ,038 (A) ,808 (B) ,857 (C) ,000 (A) ,000 (A) ,700 (A) 684,403
99 97 23 (b) (i) ,303, ,459, , (1,025,228) 1.54 (3,000) 4.97 (50,000) (D) 6.10 (593,686) , ,303,317 (A) 25% (B) (C) (D) 593,686 23(b)(ii)(D) (E) 684, ,000224,000 (A) 808,000206,000
100 98 23 (b) (i) (i (v) 38.8% 40.0% 35.0% 48.4% 46.6% 36.0% 4.766% 5.098% 4.700% 3.360% 3.130% 3.160% % 0% 0% 0% 0% 0% (i) (ii) (iii) (iv) (v)
101 99 23 (b) (ii) Hutchison MediPharma Holdings Limited ,000 (A) ,400 (B) ,187,372 (C) 1,211,772
102 (b) (ii) , ,144,505 (D) ,187,372 (E) 1.50 (80,924) 2.15 (393,212) 2.03 (120,896) (F) 1.70 (39,884) 1.79 (2,485,189) ,211, ,420 (A) (B) 25% (C) 25% 25% (D) 1,187,372 23(b)(i)(D) (E) 4.55 (F) (G) 1,211, ,000 60, ,000
103 (b) (ii) % 55% 48.4% 2.007% 2.439% 1.660% % 0% 0%
104 ,994,00015,966,000 11,068,000 10,587,000 Hutchison BYS (Guangzhou) Holding Limited5,598,000 3,626, ,0001,753,000 7,552,000 20% (i) 12.42% (ii) 50% (iii) 49 (i) 5 4 (ii) (iii) 5 3 (i) ,965 21,215 5,884 8,230 33,251 55,722 53,335 27,026 28, (897) (1,060) (11,456) (19,928) (4,253) (4,734) (18,346) (3,434) (3,265) (5,100) (9,600) (186) 51,598 49,182 43,535 29,391 (3,460) (6,059) 15,538
105 (ii) 24,828 29,500 11,531 10,157 50,202 10,272 8,286 (11,219) (2,238) 2,721 (1,215) 106 (489) (446) (21) (193) (51) 9,783 7,840 (11,219) (2,259) 2,528 (1,215) 55 (1,470) 1,352 (408) ,313 9,192 (11,627) (1,964) 2,599 (1,167) (a) 1,
106 (iii) (17,521) 2,903 3,516 (136) 6,858 (3,734) (2,457) 10,274 20,000 3,982 (4,500) (4,769) (1,255) 4,428 (984) (136) 12, ,969 8,227 4,525 4,609 (265) 314 (38) ,449 12,969 3,503 4,525 12,363 31
107 ,237 1,811 31(b) 2,190 2,352 20,427 4,163 1, , ,988 5,327 3,178 3,047 5,908 3,895 13,074 12, , ,120 13,638 15,389
108 (i) 26,923 (i) (ii) 26,282 51,508 53,205 51, % 1.80% (i) 26,923,000 (ii) (a) 26,282 51,508 26,923 53,205 51,508 (b) 53,205 48,718 2,790 53,205 51, , ,574, %87.76%
109 (a) 7,275 7,042 1,405 1, , (559) (451) (15,202) (10,937) 1,516 1, (2,903) (55) (451) (5,323) 1,412 (394) 89 (89) 324 (614) (19) (88) 2, (2,534) 160 1,320 1, (86) (490) (4,065) (3,005) (2,826) 10 2,515 (1,239) (490) (4,065)
110 (b) 9,597,000 51% 9,597 10, (i) ,208 21,105 (14,827) (105) (198) (4,769) (ii) (7,526) 8, (iii) 1,546 9,597 10,286 (9,597) 689
111 (b) (i) GSP (ii) (iii) 1,546,000 (iv) 50,202,000 55,000 71,344, ,000 (v) 23, (a) (b) ,425 1, ,734 2,888
112 (a) 7,823 7,803 4,191 3,612 6,727 6,304 2,480 9,207 6, ,
113 (b) 21 (i) 1,922 2, (i) 2,190 2,352 (i) (i) 89 (i) 1,484 1,808 1,591 1,985 (ii) 5,000 (iii) 8,694 7,374 (i) 22 8,716 7,374 (iv) (v) 2,550 4,800 3,129 5,379 (i) (ii) (iii) (iv) (v)
114 Hutchison Healthcare Holdings Limited ,500, % 87.76% 100% 100% 207,460,000 1,000,000 50% 50% 3,000,000 50% 50% 1 100% 100% 51% 63,570,000
115 % 40% 200,000,000 50% 50% 229,000,000 Nutrition Science 20, % 43.88% Partners Limited
116 114 AIM HCM P.O. Box 309, Ugland House Grand Cayman, KY Cayman Islands Computershare Investor Services PLC The Pavilions Bridgwater Road Bristol BS99 6ZY United Kingdom +44 (0) (0) Computershare Investor Services (Jersey) Limited Queensway House Hilgrove Street, St. Helier Jersey, Channel Islands JE1 1ES +44 (0) (0) (a) (b)
untitled
, BSc, ACGI, MBA, BSc, MBA, BEc, CA, BA, BA, LLL, JD, BSE, MA, MA, EdM, Solicitor, FCIS, FCS (PE), BSc, MBA, ACGI, MA, MBA, HonFCGI, BA, BMBCh, PhD, DM, DSc, FSB Panmure Gordon (UK) Limited Panmure Gordon
untitled
7 19 2016 290 3,200 1,900 2,500 1 104% 1.782 8,730 800 730 310 9,000 1. 3,190 2. 690 3. 6,000 4. 50/50 7,690 3,110 7,390 156% 5,200 2,030 AstraZeneca AB publ Nutrition Science Partners Limited 83% 3802,220
2018 Hope Education Group Co., Ltd
2018 Hope Education Group Co., Ltd. 2018 7 14 2018 8 3 1 2018 Hope Education Group Co., Ltd. 2018 7 14 2018 8 3 2 2018 Hope Education Group Co., Ltd. 2018 7 14 2018 8 3 1 Hope Education Group Co., Ltd.
: 978 2014 2 3 5 12 18 19 21 22 23 168 200 17 1701 Royal Bank of Canada Trust Company (Cayman) Limited 4th Floor, Royal Bank House 24 Shedden Road, George Town Grand Cayman KY1-1110 Cayman Islands 183
* % 129, ,280 (22.7) 20,694 55,078 (62.4) 20,230 21,598 (6.3) 170, ,956 (30.2) * % 76, ,742 (30.7) 93, ,214 (29.9) 170,
Boyaa Interactive International Limited 0434 * % 170,196 243,956 (30.2) 813,480 66,374 100,283 (33.8) 333,941 103,822 143,673 (27.7) 479,539 107,444 131,305 (18.2) 427,944 59,630 57,593 3.5 357,799 ***
2016 6 302015 2016 6 30 6 30 2016 2015 4 817,361 855,414 (682,150) (632,696) 135,211 222,718 4 9,174 2,306 (131) 897 250 (49,336) (48,034) (79,460) (7
EGL Holdings Company Limited 6882 2016 6 30 6 30 2016 2015 % 817,361 855,414-4.4 135,211 222,718-39.3 15,074 84,440-82.1 3.00 16.81 16.5% 26.0% 1.8% 9.9% 4.6% 26.5% 7-1 - 2016 6 302015 2016 6 30 6 30 2016
untitled
0151 2011 6 30 6 30 2011 2010 % 1,279,454 1,002,392 +27.6 421,920 381,658 +10.5 203,595 195,451 +4.2 1 239,122 224,216 +6.6 167,018 161,259 +3.6 % % 33.0 38.1-5.1 15.9 19.5-3.6 13.1 16.1-3.0 15.3 16.6-1.3
00C1502076 AR.indb
2014 2 3 7 11 14 23 30 32 34 35 37 38 39 114 1 2005 Cricket Square, Hutchins Drive P.O. Box 2681 GT, Grand Cayman KY1-1111, Cayman Islands 18 49 4902-03 Royal Bank of Canada Trust Company (Cayman) Limited
... 1... 5.... 6... 6... 7... 8... 8.... 9... 9... 9... 10... 10... 10... 10... 11... 14.... 16 - i -
1319 13 16 20 48 148 31-1 - ... 1... 5.... 6... 6... 7... 8... 8.... 9... 9... 9... 10... 10... 10... 10... 11... 14.... 16 - i - 13 16 20 Kwan Lik Holding Limited - 1 - 20% Kwan Lik Holding Limited Kwan
Kingsoft Cloud Chi.indb
Kingsoft Corporation Limited 03888 KINGSOFT CLOUD 2013 2 278 78 48 183 17M 2013 2 7 ......................................................................... 1 3 1..................................................................
20,232,000 4,310,000 0.33 20,232,000 19,134,000 5.7% 4,310,000 5,184,000 2014/15 2 100% 5.7% 20,232,000 19,134,000 3 2014/15 20,232,000 19,134,000 5.7% 14,351,000 13,032,000 16,783,000 16,326,000 4,310,000
,080, , (678,995) (581,252) 401, , (175,324) (76,350) 12 (292,818) (200,776) 13 11,784 14, (2,468) (859)
RICI HEALTHCARE HOLDINGS LIMITED 1526 12 31 12 311,080.12016 935.415.5% 12 31401.22016354.1 13.3% 12 3162.22016 58.9 12 31 EBITDA153.7 249.938.5% 12 31 12 31 1 12 31 12 31 11 1,080,149 935,383 12 (678,995)
i
Boyaa Interactive International Limited 0434 238 1 2 12 15 183 17M 48 ... 1... 3... 4... 5... 7... 8... 8... 8... 8... 9... 12 i 238 1 2 12 15 1 5 571 0.00005 6 2 Boyaa Interactive International Limited
40% 6 1920 21 22 40 138 15 N-1 N-3 (http://www.hkexnews.hk) (http://www.tfkf.com.hk) 183 22 .................................................................. 1............................................................
2016 2 3 6 14 15 21 31 33 35 36 37 39 103 104 1 2016 * * * * 168 200 14 1407 http://arttextile.etnet.com.hk Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1 1111 Cayman Islands Royal Bank of
,787,321 6,292,569 (3,178,103) (3,422,560) 2,609,218 2,870, ,824 85,775 (1,766,182) (2,108,497) (477,730) (536,273) (79,000) (98,0
Bosideng International Holdings Limited 3998 3 31 8.0% 5,787.3 0.5 45.1% 112.5% 280.9 708.7 2.6 3 313 31 1 3 31 3 31 3 5,787,321 6,292,569 (3,178,103) (3,422,560) 2,609,218 2,870,009 4 55,824 85,775 (1,766,182)
i
8307 2015 7 27 77 3 183 22 www.hkgem.com 2015 6 24 i ............................................................ 1 2 1...................................................... 3 2.......................................
2 981, ,770 7 (240,945) (77,087) 740, ,683 (24,901) (1,014) 715, , , , , , , , , ,28
CNQC INTERNATIONAL HOLDINGS LIMITED 1240 2 3 4 11,053,456 7,302,293 5 (9,247,614) (6,227,767) 1,805,842 1,074,526 9,598 3,763 4,228 1,504 5 (165,624) (123,375) 5 (552,981) (389,389) 1,101,063 567,029 5,681
untitled
0151 2016 6 30 6 30 2016 2015 % 9,709,476 11,137,915-12.8 4,640,456 4,728,961-1.9 2,375,732 2,273,497 +4.5 1 2,831,773 2,695,484 +5.1 1,756,442 1,749,939 +0.4 % % 47.8 42.5 +5.3 24.5 20.4 +4.1 29.2 24.2
4. 27(2) 5. 6. 7. 8. 10,000,000 1,000,000,000 0.01 9. 2
Keen Ocean International Holding Limited 1. Keen Ocean International Holding Limited 2. Codan Trust Company (Cayman) Limited Cricket Square, Hutchins Drive, PO Box 2681, Grand Cayman, KY1-1111, Cayman
5(a) 11,012,220 9,888,914 6(a) (6,674,627) (6,073,292) 4,337,593 3,815,622 5(b) 296, ,230 (1,825,164) (1,620,198) (284,865) (237,454) 6 2,523,58
Dali Foods Group Company Limited 3799 11,012,220 9,888,914 11.4% 4,337,593 3,815,622 13.7% 39.4% 38.6% 0.8 (EBITDA) 2,824,982 2,520,522 12.1% 1,969,879 1,754,799 12.3% 17.9% 17.7% 0.2 0.14 0.13 12.3% 0.085
i
GREAT WORLD COMPANY HOLDINGS LTD 8003 353 36 54 55 48 183 17M http://www.hkgem.com http://www.gwchl.com i ..................................................................... 1...............................................................
2
Baguio Green Group Limited 1397 1,028.7 821.3 25.3% 98.2 83.9 17.1% 17.7 62.5 71.7% 1.3 5,395,000 1 2 3 2013 2022 48% 55% 10 4 18 821.3 25.3%1,028.7 26.2% 930.5 737.4 17.1% 98.2 83.9 9.5% 10.2% 4 71.7%
2 3 7 8 18 29 31 33 34 36 37 39 100 01 Floor 4 Willow House Cricket Square P.O. Box 2804 Grand Cayman KY1-1112 Cayman Islands 18 2 13 2-12 305 33 18 0660 www.0660.hk 02 373,582,000 380,680,000 1.9% 8,798,000
,152 31, , ,141 5,182 2,803 10,554 6,584 57,095 8, , , , , ,457 67, ,670 38,217 1,130,205 1
YIHAI INTERNATIONAL HOLDING LTD. 1579 2 017 12 3 1 2017 12 31 2016 2017 1,646.2 2016 1,088.0 51.3% 2017 611.8 2016 416.9 46.7% 2017 261.1 2016 186.7 39.9% 2017 260.7 2016 186.7 39.6% 2017 0.269 0.267 1
, ,225 (162,513) (158,904) 76,828 69, ,552 2, ,625 (27,890) (21,426) (21,265) 8 (1,689) (1,113) 29
AP RENTALS HOLDINGS LIMITED * 1496 2016 3 31 3 31 2016 2015 239,341 228,225 +4.9 76,828 69,321 +10.8 20,923 42,925 51.3 1 42,188 42,925 1.7 2 2.94 6.02 32.1% 30.4% 2 8.7% 18.8% 2 17.4% 38.8% 1 2016 3 31
目 錄 頁 碼 定 義... I 董 事 會 函 件... 1 附 錄 I 財 務 信 息... I-1 附 錄 II 一 般 信 息... II-1 1
此 乃 要 件 請 即 處 理 閣 下 對 本 通 函 任 何 方 面 或 對 應 採 取 之 行 動 如 有 任 何 疑 問, 應 諮 詢 閣 下 之 註 冊 證 券 商 銀 行 經 理 律 師 專 業 會 計 師 或 其 他 專 業 顧 問 閣 下 如 已 售 出 或 轉 讓 名 下 全 部 康 哲 藥 業 控 股 有 限 公 司 股 份, 應 立 即 將 本 通 函 送 交 買 主 或 承 讓
GEM GEM GEM GEM GEM GEM GEM GEM GEM
Reach New Holdings Limited () : 8471 2017 GEM GEM GEM GEM GEM GEM GEM GEM GEM 1 2017 2 3 4 10 11 14 15 24 25 34 35 38 39 40 41 42 43 44 79 80 PO Box 1350 Clifton House 75 Fort Street Grand Cayman KY1 1108
: O16
: 1198 2O16 2 3 4 6 19 22 31 36 37 38 40 41 43 104 01 Donald H. Straszheim Donald H. Straszheim Donald H. Straszheim Donald H. Straszheim Royal Bank of Canada Trust Company (Cayman) Limited 4th Floor,
( ) :
() : 1198 2015 2 3 4 6 18 20 27 28 29 30 32 33 35 94 01 Donald H. Straszheim Donald H. Straszheim Donald H. Straszheim Donald H. Straszheim Royal Bank of Canada Trust Company (Cayman) Limited 4th Floor,
* % 279, ,642 (30.7) ***** 89, ,493 (48.4) 368, ,135 (36.0) * % 60, ,922 (52.2) ***** 24,550 38,508 (36.2) 84, ,430 (48.
Boyaa Interactive International Limited 0434 * % 368,972 576,135 (36.0) 735,602 129,959 170,971 (24.0) 220,730 239,013 405,164 (41.0) 514,872 250,101 361,134 (30.7) 457,267 188,002 208,054 (9.6) 243,245
: 01250 Beijing Enterprises Clean Energy Group Limited 2015 2 3 5 10 11 12 13 14 15 24 28 01 2015 Clifton House 75 Fort Street, PO Box 1350 Grand Cayman, KY1-1108 Cayman Islands 18 67 6706-07 Appleby Trust
5 25,347 26,359 (9,642) (12,913) 15,705 13, ,951 3,954 (8,797) (43,127) 7 (53,776) (1,409) (6,837) (80,268) (84,388) 8 (12,581) (13,316) (31) 9
China Vanguard You Champion Holdings Limited ( ) GEMGEM GEM GEM GEM GEM GEM GEM GEM GEM 1 5 25,347 26,359 (9,642) (12,913) 15,705 13,446 6 13,951 3,954 (8,797) (43,127) 7 (53,776) (1,409) (6,837) (80,268)
C160932347Ann.indd
Trony Solar Holdings Company Limited 2468 1 4 37,102 115,717 (38,349) (126,053) (1,247) (10,336) 5 15,609 5,844 (6,571) (7,636) (62,895) (57,313) (55,104) (69,441) 9 (2,946) (511) 7 (984) (58,050) (70,936)
Boyaa Interactive International Limited 0434 * % 159, ,370 (28.1) 735,602 52,050 63,035 (17.4) 220, , ,335 (32.3) 514, ,390 12
Boyaa Interactive International Limited 0434 * % 159,870 222,370 (28.1) 735,602 52,050 63,035 (17.4) 220,730 107,820 159,335 (32.3) 514,872 105,390 128,270 (17.8) 457,267 82,022 67,441 21.6 243,245 ***
C Ann.indd
Modern Education Group Limited 1082 20121231 20121231 128,180,0002011167,060,00023.27% 4,050,000201110,590,00061.74% 2012123120110.025 20121231 2011 1 1231 2012 2011 4 128,176 167,056 5 21,555 1,050 7
公 司 簡 介
波 司 登 國 際 控 股 有 限 公 司 ( 於 開 曼 群 島 註 冊 成 立 之 有 限 責 任 公 司 ) 股 份 代 號 : 3998 2014/15 年 報 公 司 簡 介 目 錄 2 4 8 29 39 43 57 59 61 63 65 66 68 146 148 財 務 摘 要 ( 除 另 有 指 明 外, 所 有 金 額 以 人 民 幣 千 元 為 單 位 ) 3 31 2015
1,151 561 1,694 9 34,363 18,454 25 11,235 30,046 47,292 48,525 48,443 49,086 10 34,621 29,344 3,699 4,836 6,535 39,457 39,578 7,835 8,947 8,986 9,508
CROSSTEC Group Holdings Limited 3893 1 4 132,719 130,578 (85,425) (86,376) 47,294 44,202 6 4 4 125 44 (19,949) (15,615) (11,183) 16,293 28,635 (3) 5 16,293 28,632 6 (4,785) (4,849) 11,508 23,783 (59) (59)
Kingwell_C_MT Cir.indb
KINGWELL GROUP LIMITED 1195 413 70 B1B68 18317M 48 ...................................................... 1................................................. 4.................................. 14...............................
.............................................................. 1.......................................................... 3..........................
MODERN MEDIA HOLDINGS LIMITED 72 1. 2. 3. 21 7 17 21 183 22 48 .............................................................. 1.......................................................... 3......................................................
目 錄 頁 次 釋 義......................................................... 1 董 事 會 函 件..................................................... 3 言.............
此乃要件 請即處理 閣下如對本通函任何方面或應採取的行動有任何疑問 應諮詢 閣下的股票經紀 其他持牌證 券商 銀行經理 律師 專業會計師或其他專業顧問 閣下如已售出或轉讓名下所有金嗓子控股集團有限公司的股份 應立即將本通函連同隨附的代 表委任表格送交買主或承讓人 或經手買賣的銀行 股票經紀或其他代理人 以便轉交買主或 承讓人 香 交易及結算所有限公司及香 聯合交易所有限公司對本通函的內容概不負責 對其準確性
EJE (HONG KONG) HOLDINGS LIMITED * 8101 GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM (1) (2) * 1
EJE (HONG KONG) HOLDINGS LIMITED * 8101 GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM GEM (1) (2) * 1 5 132,409 135,524 (90,801) (98,470) 41,608 37,054 5 1,905 1,674 (10,460) (8,142) (45,962) (40,726) (4,919)
4 37,919 40,859 6 (1,752) (10,323) 36,167 30,536 35,919 30, (430) 36,167 30,
RIVERINE CHINA HOLDINGS LIMITED 1417 2017 12 31 2017 12 31 2016 12 31 2017 12 31 3(a) 363,303 309,268 4(a) (296,434) (248,625) 66,869 60,643 3(b) 7,611 10,283 (4,682) (4,188) (42,690) (31,267) 5 (1,496)
C Ann.indd
SHIFANG HOLDING LIMITED 1831 1 19,125 20,443 1,266 1,500 4 5 27,013 22,907 47,404 44,850 6,472 5,583 50,511 51,527 6 101,021 7 10,314 9,714 5 4,390 5,382 220 522 117,729 109,492 290,657 182,220 338,061
GEM 2
JLOGO HOLDINGS LIMITED 8527 GEM GEM 1 GEM www.hkexnews.hk www.jlogoholdings.com 2 GEM GEM GEM GEM GEM GEMGEM 1 3 4 5 6 7 8 19 25 25 26 26 26 27 27 27 27 28 28 28 28 28 28 2 CPA, FCIS, FCS 1 22 151 Chin
cover-C- FINAL.ai
2 4 9 17 20 27 31 32 33 35 36 38 79 2. 88 35 HKICPA, FCCA HKICPA, FCCA Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands 81 16 617000 232 11 1103 Butterfield Fund Services
4. 27(2) 5. 6. 7. 8. 0.01 10,000,000,000 0.01 9.
1. 2. Codan Trust Company (Cayman) Limited Cricket Square, Hutchins Drive, PO Box 2681, Grand Cayman, KY1-1111, Cayman Islands 3. (a) (b) 4. 27(2) 5. 6. 7. 8. 0.01 10,000,000,000 0.01 9. A 1 2 3 4-7 8-9
i
China Resources Healthcare Group Limited Phoenix Healthcare Group Co. Ltd 1515 (1) (2) (3) (4) (5) (6) 9 55 56 57 58 132 2016 10 31 6 E-825 301 304 183 17M 48 2016 10 7 ... 1... 9... 56... 58... 133...
i
Overseas Chinese Town (Asia) Holdings Limited 03366 ... 1.... 4... 16... 19.... 143... 174... 180 i (i) (ii) 1 2 4 56 03366 1 2048 S 144A 73,371,900 Credit Suisse (Hong Kong) Limited 2 Pacific Climax Pacific
* % 243, , ,147 87, ,315 85, , , ,250 31, *** 82,108 56, * % 558, ,937 3
Boyaa Interactive International Limited 0434 * % 701,413 481,821 45.6 681,262 317,129 303,664 4.4 406,197 384,284 178,157 115.7 275,065 429,537 297,299 44.5 416,209 214,086 101,508 110.9 135,507 *** 235,931
Jiayuan International Group Limited , ,787, % 52% , , % % 3,
Jiayuan International Group Limited 2768 2018 12 31 2018 20,180.4 1,787,209 201795% 52% 2018 12 31 10,458.8 2,852.337.5%2018 28.4% 3,306.3 201831.6% 33.8% 2018 1,862.9 38.6% 1 1,463.2 32.5% 2018 72.21
4 3,379,679 3,207,224 (2,574,040) (2,479,550) 805, , ,999 66,818 (435,016) (374,193) (90,274) (97,935) (138) (157) 5 367, ,207 6 (7
CHANGSHOUHUA FOOD COMPANY LIMITED 1006 5.4% 3,379,700,000 3,207,200,000 10.7%805,600,000 23.8% 13.8% 359,800,000 316,100,000 12.3% 295,500,000 263,200,000 8.7% 8.2%51.5 45.9 10 1 4 3,379,679 3,207,224
44801-02A 1..33
香 港 交 易 及 結 算 所 有 限 公 司 及 香 港 聯 合 交 易 所 有 限 公 司 對 本 公 告 之 內 容 概 不 負 責, 對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明, 並 明 確 表 示 概 不 就 因 本 公 告 全 部 或 任 何 部 分 內 容 而 產 生 或 因 依 賴 該 等 內 容 而 引 致 之 任 何 損 失 承 擔 任 何 責 任 CHINA
i
Sun International Group Limited 8029 10% 22-2622 15 19 28 26 www.hkgem.com i ............................................................. 1........................................................ 3....................................................
Tao Heung Holdings Limited * 2 0 1 2 2 3 5 8 15 18 24 32 34 35 36 38 40 42 43 107 108 002 Cricket Square, Hutchins Drive, P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands 18 Royal Bank of Canada Trust
r
2 3 9 12 14 16 17 18 2 * 183 17 1712-1716 Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands 1 A 30 B&C www.inspur.com.hk 596 * Royal Bank of Canada Trust Company (Cayman)
Glorious Property Holdings Limited ,374 1, , % 1, ,895 1
Glorious Property Holdings Limited 00845 886.9 26,374 1,364.4 24,761.2 425.0% 1,585.0119,895 1 886.9 62.3% 1,364.4 1,676.9 18.6% 0.18 0.22 2 3 886.9 2,349.9 62.3% 123,81479.4% 25,535 26,374 18,980 39.0%
2 4 7 23 30 44 55 57 58 60 61 63 136 137 Huang James Chih-Cheng Huang James Chih-Cheng Appleby Trust (Cayman) Ltd. Clifton House 75 Fort Street P.O. Box 1350 Grand Cayman KY1-1108 Cayman Islands 88 1306
A 20%
TIANNENG POWER INTERNATIONAL LIMITED 00819 18 1518 48 18 15 18 5A 20% 15 18 1 5B 10% 571 0.1 2 TIANNENG POWER INTERNATIONAL LIMITED 00819 Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111
* % 268, ,789 (12.3) 38,091 87,053 (56.2) 44,533 44, , ,036 (19.7) * % 138, , ,397 31,975 (45.6) 24,303 22,596 7.
Boyaa Interactive International Limited 0434 * % 350,856 437,036 (19.7) 813,480 132,485 178,200 (25.7) 333,941 218,371 258,836 (15.6) 479,539 223,580 221,873 0.8 427,944 129,675 73,830 75.6 357,799 ***
Nexteer Automotive Group Limited % 3, , % %
Nexteer Automotive Group Limited 1316 2016 12 31 14.3% 3,842.2 2015 12 31 3,360.5 21.4% 661.7 2015 12 31 544.9 43.5% 294.7 2015 12 31 205.4 256 2016 12 31 2015 1 2016 12 31 12 31 2016 2015 2 3,842,244
2 4 6 20 27 46 57 59 60 62 63 65 150 151 Huang James Chih-Cheng Huang James Chih-Cheng Appleby Trust (Cayman) Ltd. Clifton House 75 Fort Street P.O. Box 1350 Grand Cayman KY1-1108 Cayman Islands 88 1306
企 業 簡 介.......................................................................... 2 公 司 資 料...........................................................
Intime Retail (Group) Company Limited ( ) : 1833 2013 企 業 簡 介.......................................................................... 2 公 司 資 料..........................................................................
1 2 4 5 16 21 23 24 25 26 27 28 1 CA Cricket Square Hutchins Drive PO Box 2681 Grand Cayman KY1-1111 Cayman Islands 43 19 10 1009 Butterfield Fulcrum Group (Cayman) Limited Butterfield House 68 Fort Street
untitled
SINO BIOPHARMACEUTICAL LIMITED : 1177 2017 1 1177 www.sinobiopharm.com FCCA,CPA 166 1 43 SMP Partners (Cayman) Limited Royal Bank House 3rd Floor, 24 Shedden Road P.O. Box 1586 Grand Cayman KY1-1110 Cayman
2 3 4 6 8 9 19 22 31 45 46 47 48 50 52 55 56 140 2007 8 8 2008 5 5 GDP 19 39 1.2 64% 7 11 12 9 39 235,523 261,906 394,162 305,762 1,197,353 www.maoye.cn 28 26 2 3 12 31 2012 2011 2010 2009 2008 1 11,067,240
, ,171 (188,495) (213,231) 435, , ,024 30,302 (305,546) (319,034) (56,225) (69,190) (1,876) (1
GOLDEN THROAT HOLDINGS GROUP COMPANY LIMITED 6896 2017 12 31 2016 12 31144.118.8%624.1 2016 12 31119.321.5%435.6 69.8% 2016 12 3182.9 43.8%106.2 2016 12 3141.540.3% 61.4 2017 12 31 0.06 2018 6 7-1 - 2017
Shineroad International Holdings Limited 1587 6 17 18 19 20 35 291103 06 43 44 (www.hkexnews.hk) (www.shineroad.com) 48 18322 ...................................................................... 1...............................................................
I-1... II-1... III-1... EGM-1 i
CHINA RUIFENG RENEWABLE ENERGY HOLDINGS LIMITED 527 3 10 23 18 1801 EGM-1 EGM-2 48 183 22 ... 1... 3... I-1... II-1... III-1... EGM-1 i 1 86.55% (36) 6 % 2 CHINA RUIFENG RENEWABLE ENERGY HOLDINGS LIMITED
2 4 7 8 9 10 21 26 36 50 52 53 55 56 58
2 4 7 8 9 10 21 26 36 50 52 53 55 56 58 (ACCA, HKICPA) Clifton House 75 Fort Street P.O. Box 1350 Grand Cayman KY1-1108 Cayman Islands 465 103 www.chinauton.com 23 24 2404 2014 2 26 33 Appleby Trust (Cayman)
* % 146, , ,124 20,694 (26.9) 61,026 20, , , * % 123,341 76, ,029 93, , ,
Boyaa Interactive International Limited 0434 * % 222,370 170,196 30.7 745,194 63,035 66,374 (5.0) 260,004 159,335 103,822 53.5 485,190 128,270 107,444 19.4 471,708 67,441 59,630 13.1 211,271 *** 70,711
Hao Wen_C_AR.indb
HAO WEN HOLDINGS LIMITED 2 0 1 0 (i) (ii) (iii) 01 2010 3 4 5 12 15 28 37 39 40 41 42 44 2010 02 Codan Trust Company (Cayman) Limited Cricket Square Hutchins Drive P.O. Box 268I Grand Cayman KY1-1111 Cayman
untitled
0151 2015 6 30 6 30 2015 2014 % 1,817,278 1,852,601-1.9 771,584 747,219 +3.3 370,939 394,743-6.0 1 439,799 454,823-3.3 285,527 318,450-10.3 % % 42.5 40.3 +2.2 20.4 21.3-0.9 15.7 17.2-1.5 2-13.6-10.5 1
i
COUNTRY GARDEN HOLDINGS COMPANY LIMITED 2007 2015 5 20 10 88 JW 3(1-4) 19 23 48 183 22 2015 4 14 ... 1 1.... 4 2.... 4 3.... 4 4.... 5 5.... 5 6.... 5 7.... 6 8.... 6 9.... 6... 7... 11... 19 i 2015 5
(RICI Heath) AR chi.indb
RICI HEALTHCARE HOLDINGS LIMITED : 1526 2016 2 6 8 9 10 12 16 28 48 67 81 88 2017 2017 6 2 2016 6 23 2015 5 20 2014 7 11 2013 11 6 500 2 2014 7 11 (i)(ii) 2015 2 16 2015 6 29 3 2016 10 6 2016 10 6 2008
4 1,383, ,629 (746,162) (461,904) 637, ,725 33,385 10, ,634 9,235 (119,841) (33,899) (44,891) (40,490) (47,439) (28,609) (7,671) (3,
CHINA SHENGMU ORGANIC MILK LIMITED 1432 1,383,627 905,629 +52.8% 637,465 443,725 +43.7% 333,609 279,090 +19.5% 1 4 1,383,627 905,629 (746,162) (461,904) 637,465 443,725 33,385 10,016 4 9,634 9,235 (119,841)
Boyaa Interactive International Limited 0434 * % 457, , , , , , ,969 92, , , ,231
Boyaa Interactive International Limited 0434 * % 457,951 308,927 48.2 681,262 216,982 216,094 0.4 406,197 240,969 92,833 159.6 275,065 283,851 191,231 48.4 416,209 137,836 70,160 96.5 135,507 *** 153,823
www.ione.com.hk 02 04 06 10 17 20 27 36 38 39 40 42 43 45 46 112 113 FCCA, FCPA Cricket Square, Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands 13 02 Butterfield Fulcrum Group (Cayman)
3 51,115,551 37,662,173 14,041,946 14,048,008 (12,294,931) (13,969,624) (4,241,232) (5,114,524) 38,820,620 23,692,549 9,800,714 8,933,484 3,648,828 52
Link Holdings Limited * 8237 GEM GEM GEM GEM GEM GEM GEM * 1 3 51,115,551 37,662,173 14,041,946 14,048,008 (12,294,931) (13,969,624) (4,241,232) (5,114,524) 38,820,620 23,692,549 9,800,714 8,933,484 3,648,828
C Ann.indd
20171231 20171231138.792016 46.2% 23.6%0.5 8.112016 101.3% 6.5%20164.3% 33.192016101.2% 12.299.93 * 1 20171231 20171231 2017 2016 3 13,879,207 9,495,022 (10,598,430) (7,202,155) 3,280,777 2,292,867 4 106,810
SEEC Media Group Limited SEEC MEDIA GROUP LIMITED 205 173 8 806 13 16 2826 48 ................................................................ 1 1.......................................................
(1) (2) (3)
年報 (1) (2) (3) 2 3 4 7 10 13 21 32 34 35 36 37 38 39 CPA CPA 28 29 PO Box 309 Ugland House Grand Cayman KY1-1104 Cayman Islands 168 200 21 2115 2116 Royal Bank of Canada Trust Company (Cayman) Limited
CITYCHAMP WATCH & JEWELLERY GROUP LIMITED 256 6 9 183 22 ................................................................ 1.......................................................... 3...................................................
北京市“十二五”时期卫生发展改革规划
北 京 市 十 二 五 市 级 一 般 专 项 规 划 北 京 市 十 二 五 时 期 卫 生 发 展 改 革 规 划 北 京 市 卫 生 局 北 京 市 发 展 和 改 革 委 员 会 二 〇 一 一 年 十 月 目 录 序 言... 1 第 一 章 认 真 分 析 卫 生 发 展 改 革 形 势... 2 一 十 一 五 卫 生 事 业 发 展 成 就... 2 二 目 前 卫 生 工 作 存
ii
CHINA METAL INTERNATIONAL HOLDINGS INC. 319 1 2 1 1316 183 46 48 .................................................... ii........................................................ 1....................................................
,801,000 1,473,691 20,764 12,778 (548,084) (452,982) (483,269) (395,241) (97,289) (66,548) (278,473) (209,777) (85,45
Tsui Wah Holdings Limited 1314 2015 3 31 3 31 2015 2014 1,801,000 1,473,691 22.2% # 1,266,388 1,105,011 14.6% 522,188 355,412 46.9% ## 12,424 13,268 (6.4%) 157,591 156,043 1.0% 157,407 156,031 0.9% 184
HC GROUP INC. * , , % 3,789.8 EBITDA* % % * * 1
HC GROUP INC. * 2280 1,342.6 2,447.2 182.3%3,789.8 EBITDA* 333.830.4 364.2 191.0 107.577.6% 0.17050.103964.1% * * 1 5 3,789,785 1,342,619 6(a) (3,120,495) (682,582) 16,773 22,655 6(b) 115,241 66,866 6(a)
85,426,000 39,437,000 45,989, % 30,643,000 (79,340,000 ) 48,697, % 8,794,000 6,086,000 2,708, % 7,171,000 25,573,000 18,402,000 7
CEFC Hong Kong Financial Investment Company Limited 1520 39,437,000 85,426,000 53.8% 7,171,000 25,573,000 18,402,000 72.0% 18.2% 29.9% 44,808,000 10,502,000 34,306,000 326.7% 2.65 0.94 1 85,426,000 39,437,000
HUAXI HOLDINGS COMPANY LIMITED ( ) : 1689 2016 2 3 5 9 11 19 26 28 29 30 32 33 34 77 183 1906 07 Clifton House, P. O. Box 1350 Grand Cayman, KY1-1108 Cayman Islands Appleby Trust (Cayman) Ltd. Clifton
02 04 05 07 15 17 18 19 20 41 43 02 GBS, OBE, JP GBS, OBE, JP Conyers Dill & Pearman GBS, OBE, JP GBS, OBE, JP Butterfield Fund Services (Cayman) Limited Butterfield House 68 Fort Street P.O. Box 705,
1,183, , % 1,001, , % 329, , % (1) 325, , % (1) 2
Forgame Holdings Limited 00484 1 1,183,128 776,649 52.3% 1,001,911 697,561 43.6% 329,215 283,591 16.1% (1) 325,202 240,031 35.5% (1) 2 91wan 91wan 3 47.8% 7.994 14 35 2013 2013 4 5 6 ARPG beta MPU 518,000
勤美達國際控股有限公司
CHINA METAL INTERNATIONAL HOLDINGS INC. 319 1 2 1 11 13 183 46 48 .......................................................... ii.............................................................. 1.........................................................
................................................................ 1 1....................................................... 4 2.......................
WAI CHI HOLDINGS COMPANY LIMITED 1305 11 17 21 183 22 ................................................................ 1 1....................................................... 4 2..................................................
C110122D_Vitar.indb
VITAR INTERNATIONAL HOLDINGS LIMITED 195 3 6 1 2607 13 16 48 28 26 .................................................................... 1 2..............................................................
2 4 8 12 21 31 33 34 35 36 37 38 1-2014 - 2014 2 Royal Bank of Canada Trust Company (Cayman) Limited 4th Floor, Royal Bank House 24 Shedden Road George Town Grand Cayman KY1-1110 Cayman Islands 183 22
untitled
2 3 6 13 17 25 31 44 48 49 51 52 54 116 1 Cricket Square, Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands B 9-A 1 36 SMP Partners (Cayman) Limited 3rd Floor, Royal Bank House 24 Shedden
5 11,949,401 14,705,163 (10,285,277) (9,119,336) (4,000,836) (3,078,877) (5,859,443) (6,090,711) (924,836) (795,886) (8,236,323) (11,529,150) 391,234
LEGEND STRATEGY INTERNATIONAL HOLDINGS GROUP COMPANY LIMITED 1355 1 5 11,949,401 14,705,163 (10,285,277) (9,119,336) (4,000,836) (3,078,877) (5,859,443) (6,090,711) (924,836) (795,886) (8,236,323) (11,529,150)
( 4 3,100,711 2,132,428 (1,623,168) (1,062,620) 1,477,543 1,069,808 52,722 87,098 4 47,424 28,405 (265,468) (128,111) (107,470) (101,733) 6 (99,147) (
CHINA SHENGMU ORGANIC MILK LIMITED 1432 3,100,711 2,132,428 45.4% 1,477,543 1,069,808 38.1% 800,652 711,228 12.6% 1 ( 4 3,100,711 2,132,428 (1,623,168) (1,062,620) 1,477,543 1,069,808 52,722 87,098 4 47,424
Chi.indb
China ITS (Holdings) Co., Ltd. 1900 17 48 33 18 ......................................................................... 1................................................................... 4.....................................................................
39 2016 [ ] 2016 [ ] 70 2016 [ ] 2016 [ ] 73 1992 5 27 1992 5 27 47 2013 6 2013 6 45 1993 6 1993 6 73 2015 3 20 2016 1 16 53 1992 5 1992 5 2009 1 2009
![39 2016 [ ] 2016 [ ] 70 2016 [ ] 2016 [ ] 73 1992 5 27 1992 5 27 47 2013 6 2013 6 45 1993 6 1993 6 73 2015 3 20 2016 1 16 53 1992 5 1992 5 2009 1 2009](/thumbs/40/20563325.jpg "39 2016 [ ] 2016 [ ] 70 2016 [ ] 2016 [ ] 73 1992 5 27 1992 5 27 47 2013 6 2013 6 45 1993 6 1993 6 73 2015 3 20 2016 1 16 53 1992 5 1992 5 2009 1 2009")
73 1992 5 27 2015 3 20 44 1999 6 28 2015 11 18 62 1992 5 27 2015 11 18 37 2016 1 14 2016 1 14 76 2016 [ ] 2016 [ ] 165 39 2016 [ ] 2016 [ ] 70 2016 [ ] 2016 [ ] 73 1992 5 27 1992 5 27 47 2013 6 2013 6