(1) eipo (2) (3) eipo (4) (5)
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- 赏 尤
- 7 years ago
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2 999,640,000667,540, ,100,000 99,964, ,676,000567,576, ,100, %0.003% 0.005% C %0.003%0.005% S (i) 144A(ii)S
3 (1) eipo (2) (3) eipo (4) (5) i
4 (1) (6)(7)(8) (1) (2) 1130www.eipo.com.hk (3) (4) (5) %0.005%0.003% (6) (i)(ii) (7) ii
5 (1) (8) eipo1,000, ,000, iii
6 ... i... iv I-1... II-1... III-1... IV-1... V-1... VI-1 iv
7 %85.9%83.6% MENET IMS MENET IMS MENET 2013IMS , ,864.62, % 87.3%88.1%18.5% 1
8 , , MENET
9 % , ,135.92, % % %83.5%83.6% 3
10 4
11 (i) (ii) (iii)(iv) (v) (vi)(vii) (viii)(ix) (x)(xi)(xii) (xiii) (xiv) % 55.4%56.0% %43.4%43.0% 5
12 % % %... 1,774, ,135, ,515, (301,121) (17.0) (351,813) (16.5) (413,506) (16.4)... 1,473, ,784, ,101, , , , (980,111) (55.2) (1,209,717) (56.6) (1,378,061) (54.8)... (151,566) (8.5) (157,906) (7.4) (146,508) (5.8)... (147,307) (8.3) (145,522) (6.8) (206,669) (8.2)... (19,636) (1.1) (29,145) (1.4) (24,091) (1.0) , , , (34,902) (2.0) (79,862) (3.7) (55,224) (2.2) , , , ,041 1,088,568 1,652, , ,200 1,302, , , , ,404,387 1,583,807 1,897,695 6
13 % % % , , , , , , , , , , , , , , ,102, , , , , , , , , , , , , , , , , , , , , , , , , , , , ,774, ,135, ,515, (1) %
14 ,964,000 S 899,676, ,576, ,100, % 34.6% (1)... 17,867 19,661 (2)(3) (1) 3,321,073,843 (2) 3,321,073, (3) ,865,878324,339, ,932,992200,000,
15 5.65 3,592 20%718 20%718 20%718 20%718 5%180 5%180 10%360 1,816.22,
16 ,865, CDH FlowerCPE GreeneryBeyond Border 248,711, ,110,503,913CPE Greenery CPE Palm Beach L.P.267,902,223 CPE Palm Beach L.P.Tropical Excellence CDH Flower CPE GreeneryBeyond BorderTropical Excellence 6.4%6.8%5.4%5.9% % Ginkgo Trust Limited70% 10
17 Apex Group Holdings Apex Group Holdings Limited %15% 15% BCC Research Beyond Border Beyond Border Investment Limited Beyond BorderHarvest Hill Investment Ltd. AXA Direct Asia II, L.P. Beyond Border Beyond Border 11
18 BMI A
19 CDH Flower CDH Flower Limited CDH FlowerCDH Pharmaceutical Investments Limited CDH Flower CDH Flower 32 綠 葉 製 藥 集 團 有 限 公 司 CPE Greenery CPE Greenery Ltd CPE Greenery CPEChina Fund, L.P.CPE Palm Beach L.P. CPE Greenery CPE Greenery 13
20 ,711, CDH FlowerCPE GreeneryBeyond Border eipo 99,964,000 14
21 1%0.003% 0.005% IMS IMS Health Incorporated 899,676,000567,576, ,100,000 S144A 15
22 Kang Hai Pharmaceutical Kang Hai Pharmaceutical Technology Development Limited
23 Ginkgo Trust Limited Shorea LBG Luye Hong Kong Luye Pharma Hong Kong Limited % 15%
24 MENET OECD 1% 0.003%0.005% 18
25 30 149,946,000 15% 144A S S A A 144A 19
26 332,100, (b)(2) 505(b)(2) Beyond BorderCDH FlowerCPE GreeneryTropical Excellence Solid Success Solid Success Holdings Limited
27 Steward Cross Steward Cross Pte. Ltd % 149,946, Tropical Excellence Tropical Excellence Infrastructure Pte. Ltd GIC Special Investments Pte. Ltd.Tropical ExcellenceCPE Greenery 1933 eipo 21
28 eipo % 10% 22
29 23
30 24
31 100 25
32
33 FDA 27
34 DNA G1S II 28
35 GMP GSP ACE FDA 29
36 DNA 30
37 31
38 II 32
39 DNARNA 33
40 PCT 34
41 35
42 36
43 II
44 38
45 39
46 %87.3%88.1% %60.0%60.4% %32.8%33.7% %55.4%56.0% %43.4%43.0% 40
47 % %20.6%22.8% % % %9.9%9.1% % %1.7%1.7% % 41
48 42
49
50 FDA 44
51 45
52 %13.5% %96.7% 46
53 10 47
54
55 49
56 %56.4%56.1% 50
57 51
58 52
59 53
60 %6.3%7.7% 54
61
62
63 15% 25% %25%
64 %
65 10 59
66 60
67
68 62
69 ,4404% 2,
70 100,
71
72 % 10% 50% 10%
73 25% % 10% 10% 10% 67
74
75
76 45.4% 70
77 71
78 (a) 3.05 (b) (c) (d) (e) 9.09(b)
79 41.9% CPE GreeneryCPE Palm Beach L.P. CPE Coinvest Management Limited 10.1% CPE Coinvest Management Limited Tropical ExcellenceCPE Palm Beach L.P. (i)(ii)cpe GreeneryTropical Excellence 9.09(b) (a) (b) (c) (d) CPE GreeneryCPEChina Fund, L.P.CPE Palm Beach L.P. Tropical ExcellenceCPE Greenery CPE Palm Beach L.P. CPE GreeneryTropical Excellence (i) (ii) 73
80 74
81 44B(1) D
82 Codan Services Limited 76
83 H
84 # W E
85 C 2 16A 38 15B
86
87 7 A40 Conyers Dill & Pearman
88 Clarendon House 2 Church Street Hamilton HM 11 Bermuda D (FCISFCS) W
89 Codan Services Limited Clarendon House 2 Church Street Hamilton HM11 Bermuda
90 , , % %Economist Intelligence Unit EIU , , % EIU ,95639, % , ,6009.8% 100,000 80,000 60,000 40,000 20,000 31,597 71,246 64,407 58,155 52,924 47,262 40,282 34,878 35,296 30,196 23,956 26,323 52,348 47,498 43,078 39,349 78,400 85,825 57,394 62,600 80,000 60,000 40,000 20, EIU 84
91 EIU20081, , % 20133, , % EIU EIU % %127.1 EIU ,500 2,908 3,000 2,500 2,000 1,500 1, EIU OECDEspicom %
92 (%)... 2, ,980 9, ,238 4, ,739 4, ,107 4,942 (0.8) ,970 3,732 (1.5) ,769 5, , ,404 3,010 (3.0) ,058 7, OECDEspicomEIU OECDEspicom %12.0%17.9% (%) OECDEspicom EIU 20082, , % %20178,470 86
93 EIU ( ) ,4276, , % 0.02%
94 6.5%7.0% Business Monitor International 43(CNS) (ADHD)5%
95 (1/100,000) (1/100,000) Espicom %Espicom 20171, % Espicom
96 20136,986IMS %9.2% 75%2015 GMP % MENET % 90
97 2013 % % 18.0% % 6.2% % 18.1% % 19.2% % 17.7% % 22.3% % 20.6% % 21.4% % 17.0% % 17.1% % 17.4% MENET % HPV % 0.1% 0.2% % 0.1% 0.1% 91
98 % 80% % 1.4% 1.8% % 0.7% 1.0% % 2.6% 5.5% III 1. II 2. IIII 3.
99 (International Diabetes Federation) II 80% % % 0.8% 1.3% % 0.6% 1.1% % % 0.2% 0.2% % 0.4% 0.4% EIUMENET IMSBusiness Monitor InternationalEspicomBCC Research
100
101 GMP
102 GMP GMP GMP GMP I IIIII IV 96
103 5 I (1) (2)(3) (4) (5)(6) (1) (2)(3) (4) I 97
104 3 5 6 GSP
105 GSP GSP GSP
106
107
108 15%
109 %125%
110
111
112 , %
113 (1) (2) (3) (1) (2)(3)
114 %4.07%
115
116 %15% (1) (2) (3) (4)(5) 25% % 10% 110
117 % % %10% 25% 5% % 50% 111
118 (1) 5 (2) (3) (4) (5) 60%(6) (1)(2) (3)(4) (5) (6) 112
119 (4) 113
120 199468Yantai Bio-technology Co. Ltd. Yantai Bio-tech Yantai Bio-tech62.5% 37.5% % 114
121 2009 綠 葉 製 藥 集 團 有 限 公 司 26.6% 69.6%
122 2009 Certificate of Manufacturing Facility SGS United Kingdom Ltd.ISO9001: Yantai Bio-tech62.5%37.5%Yantai Bio-tech 116
123 Yantai Bio-tech91.5% ,264, % % Yantai Luye Pharma Holdings Co. Ltd.Yantai Luye Pharma Holdings Co. Ltd. 43,590,000 Yantai Luye Pharma Holdings Co. Ltd %14%3%3% Solid Success %20071 Hui Tin Cho345.0Solid Success 117
124 Solid Success Solid SuccessSolid SuccessApex Group HoldingsKang Hai Pharmaceutical Apex Group HoldingsKang Hai Pharmaceutical Apex Group HoldingsKang Hai Pharmaceutical75% 75% Kang Hai PharmaceuticalApex Group Holdings75%21.4%3.6% Peking University Technology Development Department Peking University Weiming Biotechnology Group 30.4% 43%26.6% %19,871, Beijing Enterprises Biotech Limited Luye Hong KongPacific Target Holdings Limited26.6% 102,040, % Beijing Enterprises Biotech Limited 5,260, Luye Hong Kong69.6%
125 % 99.7%0.3% AsiaPharm Group Ltd % 6.61% 99.56%
126 248,711, %4.75% % 70% 15% (1) 0.01 (2) CDH FlowerCPE GreeneryBeyond Border % Hygeia Holdings Limited Hygeia Holdings Limited 120
127 12 105, % 7.37% %39.8%41.3% CDH FlowerCPE GreeneryBeyond Border ,711,
128 : 248,711, : ,183, ,527, : % : : 10% : LPH Group
129 : LPH Group 0.22 : (i) Hygeia Holdings Limited (ii) (iii) : LPH Group CompanyLPH Group : : LPH Group CompanyLPH GroupLPH Group 123
130 : 60% 40% 10% : 75% 60% 40% 124
131 1,110,503,913CPE Greenery 267,902,223CPE Palm Beach L.P.CPE Coinvest Management Limited CPE Palm Beach L.P.CPE GreeneryCPE Coinvest Management LimitedCPE Greenery 267,902,223Tropical ExcellenceCPE Palm Beach L.P. CPE Coinvest Management LimitedTropical Excellence 267,902,223CPE GreeneryCPE Palm Beach L.P.CPE GreeneryCPEChina Fund, L.P. CPE Greenery 306,797,245 Tropical ExcellenceGIC Special Investments Pte. Ltd.GIC Special Investments Pte. Ltd. GIC Private LimitedGIC Private Limited CDH Flower CPE GreeneryBeyond BorderTropical Excellence 6.4%6.8%5.4%5.9%Tropical Excellence 10% 8.08 HKEx-GL29-12HKEx-GL43-12HKEx-GL
132 CDH Flower CDH FlowerCDH Pharmaceutical Investments Limited CDH PIL CDH PILCDH Fund IV, L.P. CDH Fund IV CDH IV Holdings Company Limited CDH Fund IVCDH China Management Company Limited CDHCDH Fund IVCDH CPE Greenery CPE GreeneryCPEChina Fund, L.P. CPEChina CPE Palm Beach L.P. CPE Palm Beach CPEChinaCITIC PE Associates, L.P.CITIC PE Funds LimitedCPE Palm Beach CPE Coinvest Management LimitedCPEChina CPE Palm BeachCPEChina CPE Greenery 267,902,223CPE Palm Beach CPE Coinvest Management Limited CPE Palm BeachCPE GreeneryCPE GreeneryCPEChina Beyond Border Beyond BorderHarvest Hill Investment Ltd. HHI AXA Direct Asia II,L. P. AXA FundHHINew Horizon Capital III, L.P. NHCNHC New Horizon Capital Partners III Ltd. New Horizon New Horizon AXA Fund AXA FundAXA PE Asia Manager Limited AXA Fund 126
133 Nelumbo Investments Limited 70% Nelumbo Investments LimitedGinkgo Trust LimitedGinkgo Trust LimitedShorea LBG , % 2 127
134 Ginkgo Trust Limited (1) Nelumbo Investments Limited * 15% 70% 15% * * (2)(3) * * * Luye Hong Kong * * Yantai Luye Pharma Holdings Co. Ltd. * Luye Pharma Investments Pte. Ltd. * AsiaPharm Biotech Sdn. Bhd. ^ AsiaPharm Biotech Pte. Ltd. ^ 36.0% Steward Cross ^ (4) Solid Success * # SmartMedicine Sdn. Bhd. (5) Kang Hai Apex Group Holdings Pharmaceutical * * 3.6% 21.4% Shandong Luye Natural Drugs R&D Co. Ltd. # (6) (8) # 75.0% 69.6% Shandong Langhe Biotech Co. Ltd. Luye Biotech (Singapore) Pte. Ltd. A-Bio Pharma Pte. Ltd. (7) Nanjing Kanghai Phospholipid Biotech Technology Co. Ltd. # Shanghai Ge Lin Li Fu Business Consulting Co. Ltd. (9) ^ 0.3% 99.7% # Chengdu Bomai Technology Co. Ltd. 128
135 * # ^ (1) Ginkgo Trust LimitedShorea LBG Nelumbo Investments Limited (2) % (3) CDH FlowerCPE GreeneryBeyond Border0.01 (4) Steward CrossSiow Kwong ThyeMichael Tay Poh ChoonGrace Yip Yin May Ng Swee Pheng20%7%27%10% (5) SmartMedicine Sdn. Bhd (6) (7) A-Bio Pharma Pte. Ltd. (8) Beijing Beida Asset Management Co. Ltd.Beijing Beida Asset Management Co. Ltd. (9) Shanghai Ge Lin Li Fu Business Consulting Co. Ltd. 129
136 Ginkgo Trust Limited (1) Nelumbo Investments Limited * 15% 70% 15% * * * * CDH Flower CPE Greenery Beyond Border Tropical Excellence 30.1% 45.4% 6.4% 6.8% 5.4% 5.9% * Luye Hong Kong Luye Pharma Investments Pte. Ltd. * * * Yantai Luye Pharma Holdings Co. Ltd. * Asia Pharm Biotech Sdn. Bhd. ^ AsiaPharm Biotech Pte. Ltd. ^ 36.0% Steward Cross ^ Solid Success * # SmartMedicine Sdn. Bhd. Apex Group Holdings Kang Hai Pharmaceutical * * 3.6% 21.4% # # 75.0% 69.6% Shandong Luye Natural Drugs R&D Co. Ltd. Shandong Langhe Biotech Co. Ltd. Luye Biotech (Singapore) Pte. Ltd. A-Bio Pharma Pte. Ltd. Nanjing Kanghai Phospholipid Biotech Technology Co. Ltd. # Shanghai Ge Lin Li Fu Business Consulting Co. Ltd. ^ 0.3% 99.7% # Chengdu Bomai Technology Co. Ltd. 130
137 * # ^ (1) Ginkgo Trust LimitedShorea LBG Nelumbo Investments Limited (2) % (3) CDH FlowerCPE GreeneryBeyond Border0.01 (4) Steward CrossSiow Kwong ThyeMichael Tay Poh ChoonGrace Yip Yin May Ng Swee Pheng20%7%27%10% (5) SmartMedicine Sdn. Bhd (6) (7) A-Bio Pharma Pte. Ltd. (8) Beijing Beida Asset Management Co. Ltd.Beijing Beida Asset Management Co. Ltd. (9) Shanghai Ge Lin Li Fu Business Consulting Co. Ltd A
138 %85.9%83.6% MENET IMS MENET IMS MENET 2013IMS , ,864.62, % 87.3%88.1%18.5% , ,
139 MENET %
140 , ,135.92, % % %83.5%83.6% 2012 MENET %IMS , %44.1%43.8% 2012 MENET % IMS %29.5%28.7% 134
141 MENET %IMS %21.1%22.9% MENET % , ,864.62, %87.3% 88.1% IMS IMS % IMS IMS
142 IMS IMS %IMS % IMS IMS % II IMS IMS % IMS IMS % 136
143
144 IMS % 2015 IMS % 2016 IMS % IMS %2016 IMS %
145 IMS % 2017 II IMS % 2017 SNDRI IMS % 2018 II II IMS %
146 505(b)(2) , , , % 2, % 4, % 140
147 (i) (ii) (iii) (iv) % % % 141
148
149
150 144
151
152 %13.0% 146
153 % % % , , ,102, , , , , , , , , , ,774, ,135, ,515, % % % , , , , , , , , , , , , , , , , , , , , , ,577, ,864, ,215, , , , ,774, ,135, ,515, (1)
154 H ZL RU IDP IN IN EP H ZL US RU ID IN IN H EP H US JP ZL ZL Z H H H CN CN US CN H ) H H H H ZL
155 , %MENET %IMS %IMS %IMS % % %
156 % %20.1% 1999 IMS %IMS % % % 5.2% 150
157 , % % 16.0% % Lipascor
158 ,700 30%-33% LDL-C HDC C2008 IMS %IMS %IMS % , % % 2.6%
159 IMS %2013 IMS % , % %18.9% %IMS
160 II II 2013II IMS %IMS % GMP , % %53.5% ) 154
161 IMS %IMS % , % % 13.4% 155
162 501, , , %2, % 4, % 156
163 %30% 157
164 158
165 % 159
166 160
167 , %2, % 4, %
168 (89) (1) (2) (3) (4) (5)GSP 5% %16.1%15.9% %4.9%4.9%
169 9.6%11.0%10.8% GSP
170 0.8 1 GSPGSP GSP GSP 164
171 80%97%
172 %55.4%56.0% %43.4% 43.0% %20.6%22.8% 15% % %9.9%9.1%19% % % ,774.42,135.92, % ,473.31,784.12, % %83.5% 166
173 83.6%
174
175
176 BCC % FDA 170
177 6.5% %6.3%7.7% 171
178
179 (1) (1)
180 (1) (1)
181 (1) (1) (1) %40% NGT
182 IMS % IMS % 2016 Midas Pharma GmbHMidas Pharma GmbH 176
183 IMS % IMS %
184 2012PCT 2014PCT IMS % IMS %
185 1II IMS % 2017 (SNDRI) SNDRI IMS %
186 IV (DPP IV) II II 2029 IMS %
187 505(b)(2) 505(b)(2) GMP 181
188
189
190 , , GMPGMP (1) (%) (1) (%) (1) (%) (2)... 10,000 3,744 4, (3) 4, ,765 5, (4)... 10,000 44,000 5, ,000 5, ,000 5, (5)... 10,000 5, , ,000 1, (6)... 10,000 13,000 6, ,000 2, ,000 1, (7)... 10,000 80,000 52, ,000 56, ,000 77, (8)... 10, (9)... 10, , , (10) ,874 42, ,874 45, ,174 76, (1) 2608 (2) (3) % 184
191 (4) (5) (6) (7) (8) (9) (10) 58,43326, ,85043,
192 37,34830, ,15432, ,56622,
193 , , %96.7% 187
194 ; , GMP 3 GMP GMP 188
195 GMP %45.3% 48.9%, %20.5%20.5% 5% 189
196 GMP GMPISO9001:2008 ISO14001:2004CNAS GMP 190
197 GMP GMP GMP GMP 191
198
199
200 ,801155, ,014132,850326,
201 21,4404% 2, , , % 15%5 32L 6(2) 342(1)(b)34(2) 195
202 (i)(ii) (iii) (iv) (i) (ii) (iii) 196
203 30 197
204 GSP GMP (CN ) (1) GMP (SD )
205 GMP (Lu L0736) GMP (Lu I0422) GMP (Lu J0484) (2) GMP (Lu M0798) GMP (BJ ) GMP (CN ) GMP (CN ) (3) (4) (5) 199
206 GMP (JS ) GMP (SC ) (6) GMP (CN ) (7) (1) (2) (3) (4) (5) (6) (7) GSP
207 ,2893, % % % , , , , , ,
208 GMP GMPGMP 202
209 GMPGSPISO9001:2008ISO14001: ,400,0004,600,000 2,000, Beijing Haidian Environmental Protection Bureau 42,
210 %85.9%83.6% ,577.61,864.62, %87.3%88.1%18.5% , %44.1%43.8% 17.4% % 29.5%28.7%8.5% %21.1%22.9%43.3% 204
211 ,754.22, , %99.1%99.2% , , , ,135.92, % % %83.5%83.6% 205
212 Espicom %20111, %20132, %8.5%43.3% Espicom % %6.3%7.7%
213 %55.4%56.0%
214 44.3%43.4%43.0% %20.6%22.8% 15% % %9.9%9.1%19% % % ,774.42,135.92, % , ,784.12, % %83.5%83.6% 208
215 (i) (ii) (iii) (iv)
216 % 15% 25% % %9.4% 210
217 % % 55.2%
218 1231 3% %14%15%
219
220
221
222 % % %... 1,774, ,135, ,515, (301,121) (17.0) (351,813) (16.5) (413,506) (16.4)... 1,473, ,784, ,101, , , , (980,111) (55.2) (1,209,717) (56.6) (1,378,061) (54.8).... (151,566) (8.5) (157,906) (7.4) (146,508) (5.8).... (147,307) (8.3) (145,522) (6.8) (206,669) (8.2).... (19,636) (1.1) (29,145) (1.4) (24,091) (1.0) , , , (34,902) (2.0) (79,862) (3.7) (55,224) (2.2) , , , , , , , , ,
223 % % % , , ,102, , , , , , , , , , ,774, ,135, ,515, % % % (%) (%) , , , , , , , , , , , , , , , , , , (1) 53.5 (1) , , , ,577, ,864, ,215, , , , ,774, ,135, ,515, (1)
224 (2) %85.9%83.6% %0.8%1.0% % % % , , , , , , , , , , , , , , , (1) , , , , , ,
225 (1) ,195, ,0001,757,000 23%26% % % % % , ,784.12, %83.5%83.6% 219
226 ,519 5,469 30, ,823 3,858 3, , , ,093 2,627 1, ,934 12,717 35,
227 % % % , , , , , , , , , , , , , , , , , , , ,209, ,378, % % % , , , , , , , , , , , , , , , , , , , , ,
228 %92.3%93.9% %6.3%7.7% ,789 34,425 26, (3,536) (5,796) (2,596) 19,253 28,629 23, ,285 28,662 23, ,636 29,145 24,091 36%Steward Cross2007AsiaPharm Biotech Pte. Ltd.Steward Cross Steward Cross Steward Cross Steward Cross , % , %
229 ,313 57,599 87, ,058 1, (38,436) 17,205 (33,441)... 34,902 79,862 55,
230 , % 20132, %20131, % % % % %
231 % % % % % % , %2013 2, %83.6% 225
232 20121, %20131, % % % % % % % % % % % 226
233 % % % % 6.5% % % % % % % %
234 , % 20122, , % 20121, % % % % % %
235 % % % % % % %
236 % , %20121, %83.5% %20121, % % % % % % % % % % % 230
237 % %6.5% % % % % % % %
238 , , , (608,112) (135,130) (554,376) ,963 91,517 87, (149,729) 109,289 (27,430) , , , , , , (i)77.3 (ii) 36.9Shandong Biological Technology Group (iii)15.9(iv) (i)92.0 (ii)
239 (i)58.9 (ii)36.4 (iii)35.9 (i)20.1 (ii) (i)163.8 (ii)29.8 (iii)
240
241 , , , , , , , , ,178 35,092 46,413 91, ,755 12, , , ,009 2, , , , , , , , ,041 1,070,743 1,651,552 2,015, , ,041 1,088,568 1,652,370 2,015, ,331 54,403 69,369 52, , , , , , , ,921 1,081, ,310 45,218 74,436 74, ,010 26,589 34,488 57, ,902 36, , ,200 1,302,983 1,537, , , , ,
242 ,
243 ,039 50,901 95, ,503 53,883 81, ,730 37,902 57, , , , (1) (1)
244 , , , , , , , , , (3,346) (2,073) (2,192) 455, , , (1) (1) , , , ,622 12,316 18, ,009 9,956 2, ,570 3, ,767 1,576 2, , , ,
245 , , , ,710 10,401 2, ,687 12,042 2, , , , ,331 50,049 56, ,354 13,103 34,331 54,403 69,
246 (1) (1) ,007 44,436 66, ,076 7,507 2, , ,331 54,403 69,
247 ,081.91, %6.77% % % % 241
248 %
249 % % % (1) (2) (3) (4) (5) (1) (2) (3) (4) (5) %11.1% 17.3% % 6.6%9.7% %123.1% 126.8% % 6.7%21.7%
250 % 17.6%22.0% %80%
251
252 (1) (2) (3)(4) (3)(4)(5)(6) ,285,385 2,737,347 4,022, ,285,385 3,016,824 4,302, (1) ,897, (128,653).... (347,356).... (136,301)... 1,285,385 (2) ,540, (3) ,865,878324,339, ,932,992200,000,
253 (4) (5) ,321,073,843 (6) ,865,
254 20051,932, %15%15% , Steward Cross36% Steward Cross AsiaPharm (Singapore) Pte. Ltd , Shandong Biological Technology group
255
256 45.4% Ginkgo Trust Limited 70% 15% %10% 70%15%
257 %17%8% %85.9%83.6% 251
258
259 GSPGMP ,
260 254
261 % (i) 30%(ii) 255
262 256
263 A14A ,863, , ,863, %15%15% 257
264 %5%14A14A
265 10,000,000, ,000, ,831,908 8,816, % 2,212,701,935 44,254, % 667,540,000 13,350, % 3,321,073,843 66,421, % 259
266 (i)(ii)(iii) (iv)(v) 2. (c) 2. (d) 20% A
267 10% A. 5. A
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269 (1) (2) (3) Dragon Billion China Master FundLMA SPC Map 109 Segregated Portfolio Dragon Billion China Master Fund20087 Map 109 Segregated PortfolioLMA SPCLMA SPC Dragon Billion China Master FundMap 109 Segregated Portfolio OrbiMed Advisors LLC OrbiMed Advisors LLCOrbiMed OrbiMed 263
270 TAL China Focus Master Fund TAL China Focus Master FundTAL China Focus Master Fund Trivest Advisors LimitedTAL China Focus Master Fund (1) (2) (3) (4) (5) 264
271 265
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274
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276 New Asia Partners Investment Holdings Limited Luye Hong KongSolid SuccessApex Group Holdings
277 B EMBA
278 Yancoal Australia Ltd. YAL
279 SVA Emerging Markets Partnership (Hong Kong) Limited 273
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337 II. 1. 綠 葉 製 藥 集 團 有 限 公 司 Clarendon House, 2 Church Street, Hamilton HM 11, Bermuda 137 Telok Ayer Street, #05-05, Singapore (a) AsiaPharm Biotech Pte. Ltd. ABPL(b) Luye Pharma Investments Pte. Ltd. Luye Pharma Investments(c) Luye Pharma Hong Kong Limited Luye Hong Kong Pacific Target Holdings Limited) (d) Solid Success Holdings Ltd. Solid Success(a) Kanghai Pharmaceutical Technology Development Limited Kang Hai(d) Apex Group Holding Limited Apex(d) A-Bio Pharma Pte. Ltd. A-Bio(b) Luye Biotech Pte. Ltd. Luye Biotech(b) % % , I-12
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目錄
Luye Pharma Group Ltd. 綠葉制藥集團有限公司 www.luye.cn (於百慕達註冊成立之有限公司) 股份代號 2186 Annual Report 2016 年報 綠葉制藥集團有限公司 綠葉制藥集團有限公司 年報 2016 目錄 2 3 5 6 9 19 26 42 52 57 58 59 61 62 64 2 綠葉制藥集團有限公司 公司概覽 ) 34 201630 2016
.... 48 2009 4 2009 4.... 50 1997 3 2005 4.... 52 2007 10 2007 10.... 50 1994 8 2008 4.... 36 1998 7 2008 1 48 2003 7 1985198919891993 19941999 199920
11.... 48 1994 6 2003 7.... 55 1994 6 2003 7.... 49 1994 6 2003 7.... 33 2009 8 2014 3.... 38 2014 3 2014 3.... 41 2014 3 2014 3.... 36 2014 3 2014 3.... 51 2014 6 2014 6.... 65 2014 6 2014 6.... 60 2014
Luye Pharma Group Ltd. 2186 2016 02 03 05 06 14 18 19 20 21 23 24 26 中期報告 2016 02 公司概覽 30 3,400 300 10,000 1994 6 8 2004 2012 11 292014 7 9 21 03 綠葉製藥集團有限公司 公司資料 2016 6 8 2016 6 8 2016 6 8 Clarendon House
Shanghai Haohai Biological Technology Co., Ltd. * 40,000,000H 36,000,000H 4,000,000H H59.001% %0.005% H C H
Shanghai Haohai Biological Technology Co., Ltd. * 40,000,000H 36,000,000H 4,000,000H H59.001% 0.0027%0.005% H1.00 6826 32 342C H 2015423 201542859.00 48.502015428 59.00 1%0.0027%0.005%59.00 (www.hkexnews.hk)
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JINTIAN PHARMACEUTICAL GROUP LIMITED 500,000,000400,000,000 100,000,000 50,000,000 450,000,000350,000,000 100,000,000 4.23 1% 0.003%0.005% 0.001 2211
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China Xinhua Education Group Limited 400,000,000 40,000, ,000, % % 0.005% C
CHINA XINHUA EDUCATION GROUP LIMITED 中國新華教育集團有限公司 於開曼群島註冊成立之有限公司 股份代號 02779 全球發售 獨家保薦人 聯席全球協調人 聯席賬簿管理人及聯席牽頭經辦人 China Xinhua Education Group Limited 400,000,000 40,000,000 360,000,000 3.69 1.0% 0.0027%
VICON HOLDINGS LIMITED 100,000,000 10,000,000 90,000, % % 0.005% C % % 0.005% 1.2
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Q TECHNOLOGY (GROUP) COMPANY LIMITED 250,000,000 25,000, ,000, % %0.005% C %0.0027%0.005%
Q TECHNOLOGY (GROUP) COMPANY LIMITED 250,000,000 25,000,000 225,000,000 3.601.0% 0.0027%0.005% 0.01 1478 32 342C 3.602.79 3.601.0%0.0027%0.005% 2.793.60 www.hkexnews.hkqtechglobal.com (1) www.eipo.com.hkeipo
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INTRON TECHNOLOGY HOLDINGS LIMITED 250,000,000 25,000, ,000, % % 0.005% 10% C
INTRON TECHNOLOGY HOLDINGS LIMITED 英恒科技控股有限公司 : 1760 INTRON TECHNOLOGY HOLDINGS LIMITED 250,000,000 25,000,000 225,000,000 3.33 1% 0.0027% 0.005% 10% 2.61 0.01 1760 342C 2018 7 52018 7 103.33 2.90 3.33
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CHUANGMEI PHARMACEUTICAL CO., LTD. * 28,000,000 H 25,200,000 H 2,800,000 H % %0.005% H C
CHUANGMEI PHARMACEUTICAL CO., LTD. * 28,000,000 H 25,200,000 H 2,800,000 H 8.60 1.0% 0.0027%0.005% H 1.00 2289 32 342C 2015 12 7 2015 12 10 8.607.60 2015 12 10 H 8.60 1% 0.0027%0.005% H 8.60 www.chmyy.com
中期報告 2014/2015
2-4 5 6-7 8 9 10-11 12 13-14 15-23 24 1 中期報告 2014/2015 2,347,000,000 2,313,000,000 185,000,000 92,000,000 0.21 0.10 2% 1,776,000,000 17% 98,000,000 280,000,000 195,000,000 9,800 94 4,800 500 241,000,000
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2015 年 報 2 3 4 8 10 29 39 59 61 62 63 65 66 69 157 158 1 925 Clarendon House 2 Church Street Hamilton HM 11 Bermuda 18 66 (852) 2511 6016 (852) 2598 6905 Codan Services Limited Clarendon House, 2 Church
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YESTAR INTERNATIONAL HOLDINGS COMPANY LIMITED (Incorporated in the Cayman Islands with limited liability) () Stock Code : 2393 Annual Report 2015 2 4 7 10 26 30 41 53 55 56 57 59 60 62 128 Sutikno Liky
2015/2016 2 3 15 21 24 34 36 38 40 42 44 46 122 1 2 2015/2016 Clarendon House 2 Church Street Hamilton HM 11 Bermuda 26 27 2709-10 183 18 www.0030hk.com ABC Communications (Holdings) LimitedBan Loong Holdings
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COGOBUY GROUP 343,800,000 34,380,000 309,420,000 4.48 1% 0.003%0.005% 0.0000001 400 342C UBS AG 2014 7 112014 7 17 4.48 3.20 2014 7 17 144A S 2014 7 8 (2).......................... 2014 7 11..................
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361 Degrees International Limited 361 500,000,000 50,000,000 450,000,000 4.35 1%0.004% 0.005% 3.15 0.1 1361 32 342C 4.353.15 4.351.0%0.004% 0.005%4.35 (1) (2)................................ (3).........
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Wanguo International Mining Group Limited : 150,000,000 : 15,000,000 : 135,000,000 : % 0.003% 0.005% : 0.10 : C
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UNISPLENDOUR TECHNOLOGY (HOLDINGS) LIMITED 01 02 03 05 06 07 18 20 25 27 29 Clarendon House 2 Church Street Hamilton HM 11 Bermuda 1 69 02-03 132-134 1208-18 22 Codan Services Limited Clarendon House 2
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CHINA CORN OIL Company Limited 1006 09 2 3 4 11 16 26 33 35 36 37 38 39 40 82 Butterfield Fulcrum Group (Cayman) Limited Butterfield House 68 Fort Street P.O. Box 609 Grand Cayman KY1-1107 Cayman Islands
Asiaray Media Group Limited 110,000,000 11,000,000 99,000, % % 0.005% C % %0.005%
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SINOPEC KANTONS HOLDINGS LIMITED * 934 (1) (2) (3) 12 49 50 51 52 86 N-1 N-5 183 22 48 * ....................................................... 1.................................................. 12 I....................................................
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( ) ( : 993) 2 3 6 14 19 31 46 65 70 71 72 74 75 77 180 Clarendon House 2 Church Street Hamilton HM 11 Bermuda 88 29 Conyers Corporate Services (Bermuda) Limited Clarendon House 2 Church Street Hamilton
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二零一零年年報 SINO BIOPHARMACEUTICAL LIMITED SINO BIOPHARMACEUTICAL LIMITED SINO BIOPHARMACEUTICAL LIMITED (Incorporated in the Cayman Islands with Limited Liability) (Stock Code: 1177) Annual Report 2010 Annual
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2 3 6 13 17 25 31 44 48 49 51 52 54 116 1 Cricket Square, Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands B 9-A 1 36 SMP Partners (Cayman) Limited 3rd Floor, Royal Bank House 24 Shedden
Conyers Dill & Pearman Clarendon House 2 Church Street Hamilton HM11 Bermuda Butterfield Fulcrum Group (Bermuda) Limit
2011 20 1 111 25 15 44 Conyers Dill & Pearman 8 2901 Clarendon House 2 Church Street Hamilton HM11 Bermuda 1 28 2801 Butterfield Fulcrum Group (Bermuda) Limited Rosebank Centre 11 Bermudiana Road Pembroke
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ROYAL DELUXE HOLDINGS LIMITED 3789 ROYAL DELUXE HOLDINGS LIMITED 300,000,000216,000,000 84,000,000 30,000,0003,000,000 270,000,000186,000,000 84,000,000 0.671% 0.0027%0.005% 0.01 3789 32 342C 0.67 0.53
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2 3 4 8 10 12 16 31 34 38 44 45 46 47 49 50 52 132 141 Lee Huat Oon 626 MUFG Fund Services (Bermuda) Limited The Belvedere Building 69 Pitts Bay Road Pembroke HM08 Bermuda 183 22 (852) 2980 1333 (852)
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地 委 會 文 件 2016/ 第 25 號 ( 於 6.5.2016 會 議 討 論 ) 康 樂 及 文 化 事 務 署 在 元 朗 區 內 舉 辦 的 康 樂 體 育 活 動 及 設 施 管 理 綜 合 匯 報 (2016 年 5 月 號 報 告 ) 目 的 本 文 件 旨 在 向 各 委 員 匯 報 康 樂 及 文 化 事 務 署 ( 康 文 署 ) 於 2016 年 2 月 至 5 月 在
GenNex Holdings Limited [] [] [] [] [] [] []1.0% 0.0027% 0.005% 0.01 [] [] [] 342C [][] [] [] [][] [][] [][] []
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GenNex Holdings Limited (a) (b) (c) (d) (e) (f) (g) (h) (i) (j) (k) GenNex Holdings Limited [] [] [] [] [] [] []1.0% 0.0027% 0.005% 0.01 [] [] [] 342C [][] [] [] [][] www.hkexnews.hkwww.gennexholdings.com
[] Honma Golf Limited 133,991,000 13,400,000 120,591,000 10.981.0% 0.0027%0.005% 0.0000025 6858 32 342C 10.98 8.4610.981.0% 0.0027%0.005%10.98 144A144A S (1) www.eipo.com.hkeipo (2)... (3)...... eipo...
HUAJUN INTERNATIONAL LIMITED NEW ISLAND DEVELOPMENT HOLDINGS LIMITED * 377 7 15 16 20 21 22 23 43 33 18 * .......................................................... 1................................................................
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KML Technology Group Limited (a) (b) (c) (d) (e) (f) (g) (h) (i) (j) (k) 32 [ ] KML Technology Group Limited [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ][] [ ] [ ] 1%0.0027% 0.005% [ ] 0.01 [ ] [ ] [ ]
Zhejiang Cangnan Instrument Group Company Limited : 17,296,667 H : 15,566,967 H : 1,729,700 H : H % %0.005% : H1.00 : C
Zhejiang Cangnan Instrument Group Company Limited 浙江蒼南儀錶集團股份有限公司 ( 於中華人民共和國註冊成立的股份有限公司 ) 股份代號 : 1743 全球發售 獨家保薦人 獨家全球協調人及獨家賬簿管理人 Zhejiang Cangnan Instrument Group Company Limited : 17,296,667 H : 15,566,967
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KML Technology Group Limited 8065 KML Technology Group Limited 100,000,000 10,000,000 90,000,000 0.72 0.48 1% 0.0027% 0.005% 0.01 8065 32 342C 0.72 0.480.72 1%0.0027%0.005%0.72 0.480.72 www.hkexnews.hk
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CHINA SEVEN STAR HOLDINGS LIMITED 245 (1) (2) (3) (4) (5) 6 41 42 43 44 68 57 73 EGM 1 EGM 3 48 183 22 ............................................................ i............................................................
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Dragon Crown Group Holdings Limited 275,000,000 27,500,000 247,500,000 1.40 1% 0.003%0.005% 0.10 935 32 342C 2011 6 2 2011 6 3 1.40 1.01.40 1% 0.003% 0.005% 1.4 1.01.40 www.dragoncrown.comwww.hkexnews.hk
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Grand Brilliance Group Holdings Limited 君百延集團控股有限公司 於開曼群島註冊成立的有限公司 股份代號 : 8372 股份發售 獨家保薦人 獨家全球協調人 聯席賬簿管理人及聯席牽頭經辦人 瑞邦證券 有限公司 GRAND BRILLIANCE GROUP HOLDINGS LIMITED GEM 168,000,000 151,200,000 16,800,000
Pak Fah Yeow International Limited PAK FAH YEOW INTERNATIONAL LIMITED * 239 4 9 10 11 17 238 3 22 23 200 11 * ............................................................... 1.........................................................
Putian Communication Group Limited 275,000,000 27,500, ,500, % % 0.005% C %
PUTIAN COMMUNICATION GROUP LIMITED : 1720 Putian Communication Group Limited 275,000,000 27,500,000 247,500,000 0.95 1.0% 0.0027% 0.005% 0.01 1720 32 342C 2017 11 1 2017 11 30.950.51 0.95 1.0% 0.0027%
4 3,921,601 3,313,992 (3,581,803) (2,836,682) 339, , ,458 (50,586) 7 26,373 10,239 (96,948) 196,271 (117,699) (84,620) (323,646) (309,559
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B & S International Holdings Ltd. 1705 B & S INTERNATIONAL HOLDINGS LTD. 100,000,000 10,000,000 90,000,000 1.001.0% 0.0027% 0.005% 0.01 1705 32 342C 1.000.80 www.hkexnews.hkwww.bandshk.com (1) www.hkexnews.hk