Pharma Corporation Jacobson Pharma Corporation Limited [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] 0.01 [ ] [ ] C [ ] [ ] [ ] [ ] [

Jacobson Pharma Corporation Limited (a) (b) (c) (d) (e) (f) (g) (h) (i) (j) (k)

Pharma Corporation Jacobson Pharma Corporation Limited [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] 0.01 [ ] [ ] 32 342C [ ] [ ] [ ] [ ] [ ] [ ] [ ][] [ ][] [ ] [][][[][][][][][ ][ ] [ ][[] ][ ] [ ][ ][ ] [ ] [ ] [ ] [][][][ ] [ ] [ ] [ ] [][] [ ] [ ] [ ] [ ] [ ] [ ][ ] [ ] [ ] [] [ ] [ ] [ ] [ ] [ ]

(1) [ ] i

(1) [ ] ii

[] [][ ] [][][] [ ] [ ] [ ][ ] [ ] [ ] [ ][ ] [ ] www.jacobsonpharma.com............................................................ [i].................................................................. [iii].................................................................. 1.................................................................. 12.............................................................. 25............................................................ 31.............................................................. 32 [ ]............................................. 55 [ ]................................................. 58.............................................................. 61.............................................................. 63.............................................................. 74................................................. 93.................................................................. 105.............................................................. 151..................................................... 188.................................................................. 198..................................................... 201.............................................................. 205 [ ]................................................. 206 iii

[ ]................................................................ 208 [ ].......................................................... 216 [ ]........................................................ 225................................................. [I-1]...................................... [II-1]............................................... [III-1]....................... [IV-1]............................................. [V-1].............................. VI-1 iv

[ ] [ ][ ] 30% (i) 70%(ii) 20% 68.8%50.1%52.1%65.0%29.9% 36.0% 97.0%26.6%88.8%96.3% 85.0%85.0% 1,000 900 49.4%56.6% 30.9% 3,000 68.3% 1

863824 PIC/S GMP PIC/S 28 2923.2% 715.8 13.3% 811.3...................... 1 78.4% 441.2 8.4%........................ 1 17.9% 590.9 12.2%................. 1 12.9% 488.0 11.4%.......................... 1 16.8% 361.6 9.2%........................ * 36.0% 87.7 10.6%...................... 1 12.2% 196.4 12.0% * 2

.................................................. 86 PIC/S GMP GMP 16 352 1,000900 3

1,000900 39.3%37.0% 35.9% 31.5%29.7% 28.1% 17.8%19.6% 19.1% 4.0%5.0% 4.1% 4

.................. 926,181 100.0 947,591 100.0 715,830 100.0 811,256 100.0.............. (501,339) (54.1) (562,883) (59.4) (420,693) (58.8) (435,648) (53.7).................. 424,842 45.9 384,708 40.6 295,137 41.2 375,608 46.3...... 65,172 7.0 6,005 0.6 2,667 0.4 (1,887) (0.2)....... (97,974) (10.6) (105,061) (11.1) (79,660) (11.1) (104,222) (12.8)... (169,123) (18.3) (146,810) (15.4) (109,392) (15.3) (113,636) (14.1).............. 222,917 24.0 138,842 14.7 108,752 15.2 155,863 19.2.............. (5,969) (0.6) (2,707) (0.3) (2,368) (0.3) (2,507) (0.3)............ 216,948 23.4 136,135 14.4 106,384 14.9 153,356 18.9................ (32,247) (3.5) (22,157) (2.4) (17,652) (2.5) (25,262) (3.1)........ 184,701 19.9 113,978 12.0 88,732 12.4 128,094 15.8.......... 292,134 31.5 281,844 29.7 210,761 29.4 227,741 28.1........ 531,600 57.4 557,167 58.8 421,313 58.9 475,183 58.5......... 823,734 88.9 839,011 88.5 632,074 88.3 702,924 86.6................ 102,447 11.1 108,580 11.5 83,756 11.7 108,332 13.4.................. 926,181 100.0 947,591 100.0 715,830 100.0 811,256 100.0 (i) (ii) (iii) (iv) 6

.............. 374,103 45.4 333,727 39.8 254,579 40.3 324,740 46.2................ 50,739 49.5 50,981 47.0 40,558 48.4 50,868 47.0.................. 424,842 45.9 384,708 40.6 295,137 41.2 375,608 46.3 45.9% 40.6% PIC/S 41.2% 46.3%.................................... 1,011,869 1,311,176 1,373,640...................................... 444,940 394,035 490,980...................................... 488,914 650,238 681,922................................. 43,974 256,203 190,942........................... 967,895 1,054,973 1,182,698 50,908 48,338 51,176...................................... 916,987 1,006,635 1,131,522............................. 877,894 957,343 1,076,263.................................... 39,093 49,292 55,259...................................... 916,987 1,006,635 1,131,522 7

...... 150,272 161,754 117,857 175,957........ (126,529) (390,971) (318,653) (96,774) (8,747) 160,853 117,043 (15,929)................. 14,996 (68,364) (83,753) 63,254................. 116,778 131,492 131,492 63,005................ (282) (123) 52 311................. 131,492 63,005 47,791 126,570 (%)................................................ 45.9 40.6................................................ 19.9 12.0............................................ 20.7 10.6......................................... 12.8 6.4...................................... 0.91 0.61 0.72...................................... 0.58 0.35 0.44............................... 18.3% 40.3% 30.9% [ ] [ ] Kingshill Longjin [ ] 8

Kingshill The Kingshill TrustTrust CoThe Kingshill Trust Longjin 75% Kingshill Longjin LongjinLongjinKingshill Longjin[]%[ ] KingshillLongjin [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [][][] [ ] [ ] [ ] [ ] [ ] [ ] [ ] 9

[ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [][][] [ ] [ ] [ ].................................................... [] [] (1).................... [] [] 1. 15.022.8200.2[ ] [ ] [ ] [ ] [ ] [ ] [ ][[] ][ ] [ ] [ ] [[] ][ ] [ ] [ ] (i) 35% (ii) 10% [ ] 10

[ ] [ ] 10.0 [ ] [ ] 123 24 25 14 [] 11

[ ] [ ] 1 6 223 [ ] 12

[ ] 549 [ ] 622 32 [ ] 13

[ ] Kingshill Longjin KingshillLongjin [ ] 14

2819 Europharm HoldingsEuropharm Investment 75%14.31% 10.69% Europharm Holdings Europharm Holdings (BVI) Limited Europharm Investment Europharm Investment Limited 80 1,000 12 [ ] 15

[ ] [ ] [ ] [ ] 16

[ ] [ ] [ ] [ ] 17

JPG (BVI) Jacobson Pharma Group (BVI) Limited Kingshill Kingshill Development Limited 55.2% [ ] [ ] Longjin Longjin Investments Limited 75% 25% 18

[ ] Merck (Germany) Merck Holding GmbH Merz (Germany) Merz Pharma GmbH & Co. KGaA 19

[ ] 20

[ ] [ ] Queenshill Queenshill Development Limited [ ] [ ] 21

571 0.01 D. 2. D. 1. [ ] [ ] 15 22

The Kingshill Trust The Kingshill Trust Trust Co Kingshill Development Group Inc. UBS Trustees (BVI) LimitedThe Kingshill TrustKingshill Ultra Perfect Profit Ultra Perfect Profit Limited 75% 25% [ ] 23

[ ] 24

Contractubex 26

GMP GSDP HOKLAS 27

PIC PIC/S GMP QbD ASP 138 13 SAP SAP SE HMG-CoA 29

138 30

31.5%29.7%28.1% 50 100 32

619 PIC/SGMP PIC/S GMP 33

31.5%29.7% 28.1% 37

[ ] 133.3 17.6% 4.9% 39

[ ] 44.0 256.2 190.9 159.0 311.0261.8 476.7 70.0 40

PIC/S GMP GMP 41

37,974 24 25 44

14 40(1BA) (a)200,000 (b) 20,000 123 14 24 45

851.6 879.1 743.9 91.9%92.8% 91.7%[ ] 46

10% 25% 5%10% 47

(i)(ii) (iii) 5 15 [ ] 48

[ ][] [ ][] [ ][] 698 698698 49

7698 7 (1) 80%(2) (3) 698 7 10% 7 [ ] [ ] [ ] [ ] [ ] [ ] [ ] [] [] [ ] [] [ ] [ ] [ ] [ ] [ ] 50

15.0 22.8 200.2 [ ] [ ] [ ] [ ] [][][][] [ ] [ ][] [ ] [ ] 51

[ ] [ ] Kingshill Longjin[ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] 52

3. 53

[ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] 54

[ ] [ ] 55

[ ] [ ] 56

[ ] [ ] 57

[ ] 2B 3 18 A 153E 89 6 55 F 23 2 5 A 600 10 5 D 89 8 22 C 11 1 10 A 58

[ ] [ ] 1 26 [ ] [] 10 8 15 12 38 12 6 Conyers Dill & Pearman Cricket Square Hutchins Drive PO Box 2681 Grand Cayman KY1-1111 Cayman Islands [ ] 15 33 59

[ ] 77 3 34 500 B 1018 200232 1 16 60

Cricket Square, Hutchins Drive PO Box 2681, Grand Cayman KY1-1111, Cayman Islands 388 1 1 23 2313-18 www.jacobsonpharma.com (FCPA, FCCA) 388 1 1 23 2313-18 388 1 1 23 2313-18 388 1 1 23 2313-18 61

[ ] [ ] 21 1 10 4-4A 13 62

[ ] [ ][ ] [ ] 876,000 (i)(ii) 44.4% 417347 (i)(ii) 63

6.6% 7.0% 180 164.1 160 152.4 140.8 140 129.2 78.9 83.7 88.1 93.4 102.0 108.0 114.1 121.4 120 100 80 60 40 4.7% 5.0% 5.2% 5.1% 5.2% 5.3% 5.2% 5.2% 5.3% 5.3% 5.3% 5.3% 20 0 14% 12% 10% 8% 6% 4% 2% 0% 7891,020 6.6%1,641 5% 20.0 18.0 16.0 14.0 12.0 10.0 8.0 6.0 4.0 9.2 1.0 8.2 10.1 1.0 9.1 10.9 1.1 9.9 11.8 1.2 10.6 13.6 12.7 1.4 1.3 11.4 12.2 16.5 14.5 13.0 15.5 1.5 1.6 1.7 13.9 14.8 17.6 1.7 15.9 2.0 0.0 64

65 90.0% 6.3% 82114 8.4%159 6.8% 10 137.0% 17 6.3% 8.4% 7.1% 12.7% 7.2% 6.8% 6.0% 9.9% 5.6% 0 2 4 6 8 10 12 14 16 18 5.3 1.8 1.1 8.2 5.8 2.1 1.2 9.1 6.2 2.4 1.3 9.9 6.6 2.6 1.4 10.6 7.0 2.9 1.4 11.4 7.4 3.3 1.5 12.2 7.9 3.6 1.5 13.0 8.3 4.0 1.6 13.9 8.8 4.3 1.7 14.8 9.2 4.7 1.9 15.9

* 12,000 10,000 8,000 6,000 4,000 2,000 0 13.1% 842.9 13.3% 820.3 0-14 15-64 65 0.8% -1.2% 0.5% 3.7% 0.9% -1.1% 0.4% 4.2% 13.7% 815.6 14.2% 797.1 14.7% 920.2 940.5 980.2 1,021.5 1,065.9 1,109.6 1,157.3 1,209.4 1,260.2 1,311.9 804.4 15.2% 792.3 0-14 15-64 65 15.7% 5,261.1 5,303.7 5,358.8 5,368.9 5,374.1 5,390.2 5,411.8 795.5 16.3% 5,433.4 779.6 16.8% 779.6 65 17.4% 5,460.6 5,487.9 760.9 19% 17% 15% 13% 11% 9% 7% 5% * 6513.1%14.7% 182 198194 800 2,800 70 10%12% 66

46% 29 12.7%47 9.9% 205 18 164 14 123 10 82 6 41 1.8 2.1 2.4 2.6 2.9 3.3 3.6 4.0 4.3 4.7 2 0 150 Olmesartan Rosuvastatin Aripiprazole 67

60 30%............................................ 32.7%............................................ 14.6%............................................ 11.5%............................................ 10.8%............................................ 7.3% 170.5 5.8% 196.4 6.7% 376.6 12.8% 314.6 10.7% 361.6 12.3% 590.9 20.1% 441.2 15.0% 488.0 16.6% 68

20.1%16.6%15.0%12.3%10.7%6.7%5.8% 32.7% 100.0% 80.0% 78.4% 60.0% 40.0% 20.0% 17.9% 16.8% 12.9% 12.2% 0.0% 700 600 7.0% 500 4.1% 400 300 200 379.4 433.0 431.9 434.7 446.1 479.2 521.7 556.2 591.3 626.4 100 0 69

379.4 446.1 4.1%626.4 7.0% 70% 100.0% 80.0% 60.0% 68.8% 65.0% 52.1% 50.1% 40.0% 29.9% 20.0% 0.0% 125.3 170.8 8.0%264.3 9.1% 70

300 250 9.1% 9.1% 200 150 8.0% 220.8 241.4 264.3 202.2 100 185.5 50 125.3 135.1 146.1 157.7 170.8 0 97.0% 41.4%41.9% 42.4% 64.0 100.3 9.4% 20.5% 6,836 56.0% 11.9%32.1% 8.2% 71

2,000 1,800 1,600 1,400 1,200 1,000 800 600 400 200 0 743.1 59.4 210.3 473.3 864.2 75.2 259.3 529.7 995.5 86.2 314.0 595.3 1,122.0 116.7 359.0 646.3 1,220.7 145.3 391.8 683.6 1,324.5 180.1 423.8 720.5 1,434.4 225.4 460.4 748.8 1,549.2 258.7 500.4 790.1 1,668.4 298.7 542.2 827.5 1,791.9 333.3 580.6 878.0 13.2% 25.0% 16.8% 9.6% 8.0% 18.1% 8.2% 5.1% 12,207 13.2% 17,919 16.9% 5.5% 10.0% 14 30 16.8%58 26.6% 102.8 18.6% 198.614.1% 72

50.4% 1,752.2 14.2%3,051.7 11.7% 14.8 23.6 12.5% 45.1 13.8% 88.8% 1,000 14,000.0 12,000.0 10,000.0 8,000.0 6,000.0 13,224.2 11,781.9 11,286.3 9,245.0 6,473.3 400.0 350.0 300.0 250.0 200.0 150.0 264.2 345.0 219.2 167.4 198.7 4,000.0 100.0 2,000.0 50.0 0.0 0.0 73

138 138A 100,0002 (i) (ii) I II I II I II 74

I II 137 529 134 134A 450,000 3 75

132 V 50 10,000 52 53 10,000 54 54 50,000 61 132W 3 1 1 50,000 549 549 119 121 119 100,000 76

131 134 143 549F 26 144 28 28 354C 6 1 8 21 68 21 200,000 77

56 (i) 30,000 (ii) 10,000 (iii) 14 26 303 50,000 2,500 303B 6,000 (i) (ii) (a) (b) 78

50,000 586 1 III III 500,000 1 60 6C 3 60A1 1 6D 3 2 2 3 2 60E 4 5 14 14(1)1,000 (2) 100 4 5 10,000 79

7 4 5 145 12 3 (1) 1 (2) 2 (3) 3 145A 1 2 3 4 1 2 3 231 (i) 1 (ii) 2 1 2 (1) (2) (3) 80

(i)(ii) 50,0006 100,000 1 362 2 7 7A 13E13F13G13H 13I (a)(b)(c)(d) (e) 77A13E13F13G13H 13I 500,000 5 100,000 2 559 599A 10 14 81

48 19 21 18 23 25 528 26 (a) (b)(c) 622 122 32429 431 300,000 300,000 12 619 82

93 3 10% 549 3 83

2015 (GMP) 5 6 GMP GMP 6 GMP 84

I II III IV 85

117 1622 230 117 230 (i) (ii) (iii) 86

15% 88

20 10 10 10 89

25% 25% 10% 10% 5% 17% 91

25%10% 25% 5% 10% 50% 92

KingshillGreat Era Corporation20%60% 20% Great Era Corporation 20% 20%80% 18 30% 3M Littmann Merck (Germany) Merz (Germany)Contractubex 500 93

5,000,000 GMP PIC/S GMP JPG (BVI) JPG (BVI) Europharm International Holdings (BVI) Limited 54 Kingshill Ultra Perfect Profit 32% 68% Kingshill34.0Ultra Perfect ProfitJPG (BVI)19% Kingshill Queenshill 103.3 Ultra Perfect Profit JPG (BVI)37%Queenshill Longjin Ultra Perfect ProfitJPG (BVI) 12% JPG (BVI)KingshillQueenshill Longjin 51%37% 12% 94

24 (2) (2) (2) (2) (2) (2) Jacobson Group Management Limited (1) Jacobson Group Treasury Limited (1) (2) (2) (2) (2) (2) Li Chung Shing Tong (S) Pte Limited (2) (1) 160,000 108,600,000 8,750,000 1,100,000 25,292,982 11,000,000 10,000 10,000 26,628,000 10,000 56,978,199 10,000 5,000,000 50,000 100,000 95

(2) 10,000,000 (2) 10,000 (2) 3,000,000 (2) 1,000,000 (1) 10,000 (2) 10,000 (2) 4,680,000 (2) 500,000 (2) 66,165,000 (1) (2) 96

25% 75% 100% 100% Longjin Kingshill Queenshill 12% 51% 37% Jacobson Pharma Group (BVI) Limited 100% 100% 100% 100% 100% 100% 100% 100% Jacobson Group Management Limited Jacobson Group Treasury Limited Jacobson Medical Holdings (BVI) Limited Frankin Laboratories Holdings (BVI) Limited Universal Laboratories (Holdings) Limited Golden Jade Finance Limited Majestic Path Limited Ferguson Healthcare Holdings (BVI) Limited 100% 100% 100% 100% 100% 100% Jean-Marie Pharma Holdings (BVI) Limited 100% 100% 100% 100% 100% Europharm Holdings (BVI) Limited Europharm Investment Limited APT Pharma Holdings (BVI) Limited PCHT Herbal Sciences Limited Gorgeous Spirit Limited 100% 100% Marching Inter-pharma Limited 100% 100% Janson Holdings Limited Magic Fountain Inc. 100% 100% Vickmans Holdings (BVI) Limited Jean-Marie Holdings (BVI) Limited 75.0% 14.31% 100% APT Interpharma (BVI) Limited 92.4% Po Chai Herbal Technology Limited (2) 100% 100% Great Era Corporation Citi-Ascent Limited 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% Fountain Good Inc. Li Chung Shing Tong (S) Pte Ltd 100% 100% 100% 62.0% 100% 100% Wishland Limited Synco Pharma Holdings (BVI) Limited ( ) (5) Quinwood Limited (3) 100% 55.2% 100% 100% 100% Blossomy Rose Inc. (4) 100% 100% 100% 97

(1) (4) (2) Po Chai Herbal Technology Limited (PCHT) PCHT (3) (5) (4) (6) (5) [ ] 50,000,0005,000,000,000Kingshill Queenshill Longjin 51%37% 12% JPG (BVI) KingshillQueenshill Longjin JPG (BVI) 51%37% 12% 667,410,000 484,198,000 157,038,000 KingshillQueenshill Longjin Po Chai Herbal Technology Limited PCHT7.6% PCHT PCHT7.6% 3,754,000 The Kingshill Trust The Kingshill Trust Queenshill Kingshill14% The Kingshill TrustKingshill 98

The Jacobson Pharma (PTC) Limited The Jacobson Pharma (PTC) Limited[ ] [] Queenshill The Jacobson Pharma (PTC) Limited3% D. 2. Kingshill Longjin LongjinLongjin 99

[ ] The Kingshill Trust (1) 100% The Jacobson Pharma Turst Co (1) (3) (PTC) Limited (2) 25% 75% 100% 100% Longjin Kingshill Queenshill 11.97% 64.81% 19.94% 2.99% 0.29% 100% Jacobson Pharma Group (BVI) Limited* 100% 100% 100% 100% 100% 100% 100% 100% Jacobson Medical* Jacobson Group Jacobson Group Frankin Laboratories* Universal Laboratories Golden Jade Finance Ferguson Healthcare Holdings Majestic Path Limited* Management Limited Treasury Limited Holdings (BVI) Limited (Holdings) Limited* Limited* Holdings (BVI) Limited* (BVI) Limited 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% APT Pharma* Jean-Marie Pharma Europharm Holdings Europharm Investment PCHT Herbal Sciences Marching Inter-pharma Janson Holdings Holdings Gorgeous Spirit Limited* Magic Fountain Inc.* Holdings (BVI) Limited* (BVI) Limited* Limited* Limited* Limited* Limited* (BVI) Limited 100% 100% 75.0% 100% 100% 100% 100% 100% 100% 100% Vickmans Holdings Jean-Marie Holdings 14.31% APT Interpharma (BVI) Po Chai Herbal Great Era Corporation* Citi-Ascent Limited (BVI) Limited* (BVI) Limited* (4) Limited* Technology Limited* 100% 100% 100% 100% 100% 100% 100% 100% Li Chung Shing Tong (S) Fountain Good Inc. Pte Ltd 100% 100% 62.0% 100% 100% Synco Pharma Holdings Quinwood Limited (5) (BVI) Limited* (7) 100% 55.2% 100% 100% 100% (6) Blossomy Rose Inc. 100% 100% 100% 100

[ ] [ ] The Kingshill Trust (1) 100% Turst Co (1) The Jacobson Pharma (3) [] (PTC) Limited (2) 25% 75% 100% 100% Longjin Kingshill Queenshill [] [] [] [] [] [] 100% Jacobson Pharma Group (BVI) Limited* 100% 100% 100% 100% 100% 100% 100% 100% Jacobson Medical Jacobson Group Jacobson Group Frankin Laboratories Universal Laboratories Golden Jade Finance Ferguson Healthcare Holdings Majestic Path Limited Management Limited Treasury Limited Holdings (BVI) Limited (Holdings) Limited Limited Holdings (BVI) Limited (BVI) Limited 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% APT Pharma Jean-Marie Pharma Europharm Holdings Europharm Investment PCHT Herbal Sciences Marching Inter-pharma Janson Holdings Holdings Gorgeous Spirit Limited* Magic Fountain Inc.* Holdings (BVI) Limited* (BVI) Limited* Limited* Limited* Limited* Limited* (BVI) Limited* 100% 100% 75.0% 100% 100% 100% 100% 100% 100% 100% Vickmans Holdings Jean-Marie Holdings 14.31% APT Interpharma (BVI) Po Chai Herbal (4) Great Era Corporation* Citi-Ascent Limited (BVI) Limited* (BVI) Limited* Limited* Technology Limited* 100% 100% 100% 100% 100% 100% 100% 100% Li Chung Shing Tong (S) Fountain Good Inc. Pte Ltd 100% 100% 62.0% 100% 100% Synco Pharma Holdings Quinwood Limited (5) (BVI) Limited* (7) 100% 55.2% 100% 100% 100% (6) Blossomy Rose Inc. 100% 100% 100% 101

* ** 3.5 Wishland Limited (1) KingshillTrust CoTrust CoUBS Nominee Limited UBS Trustees (BVI) LimitedTrust Co The Kingshill Trust (2) The Jacobson Pharma (PTC) Limited[ ] (3) Quinwood Limited (5) (6) (4) (5) Quinwood LimitedPCHT (6) PCHT (7) (a) 29.7 (b) 11.8 (c) 52%23%14.31% 74.3 102

(d) 75%25% 44.0 (e) 40.0 (f) 59.0 (g) Gobitech Limited Gobitech 66.8% 24.0 Gobitech Gobitech33.2% Gobitech Gobitech Gobitech 16.2 Gobitech (h) PCHT 45.6% 46.8%125.0 PCHT PCHT (3)(5) (6) PCHT 103

PCHT 7.6% 3,754,000 PCHT (i) (j) Great Era Corporation 160.0 Great Era Corporation 83.8 (k) 67.9 (l) 38.6 104

30% (i) 70%(ii) 20% 68.8%50.1%52.1%65.0%29.9% 36.0% 97.0%26.6%88.8%96.3%85.0% 85.0%...................... 1 78.4% 441.2 8.4%........................ 1 17.9% 590.9 12.2%................. 1 12.9% 488.0 11.4%.......................... 1 16.8% 361.6 9.2%........................ * 36.0% 87.7 10.6%...................... 1 12.2% 196.4 12.0% * 1,000 900 105

49.4%56.6% 30.9% 3,000 68.3% 86 2438 PIC/S 28 29 23.2% 715.8 13.3% 811.3 (i) (ii) 106

30% (i) 70%(ii) 20% 3,000 68.3% 68.8%50.1%52.1%65.0% 29.9% 36.0% 29 23.2% 9.9%47 26.8% PIC/S PIC/S 19.917.6 14.2%1,029.3 1,752.2 11.7%700 107

36.186.2 76.1 50.4% 97.0% 26.6% 88.8%96.3%85.0%85.0% 2013 2014 2015 2015 8.0% 125.3 170.8 9.1% 49.4%56.6% 30.9% 3,00068.3% 108

46.6 46.4 86 24 38 3669 26 Merck (Germany) 50 60 109

1,000 900 SAP 30 GMP PIC/S GMP PIC/S PIC/S GMP PIC/SGMP GMP RABS 110

28 GMP 10 PIC/S 700 111

PIC/S 44.9 75.3 13.8% 11.2% 128.2 10.8 19.6 37.4 13.8% 30 112

86 PIC/S GMP GMP 113

16 3 52 1,000 900 SAP 17.8% 19.6% 19.1%4.0%5.0% 4.1% 7 18 7 90 39.3%37.0% 35.9%31.5%29.7% 28.1%6 18 108 114

............................................ 11 100%............................... 37 >90%............................. 45 >95%............................. 66 >90%............................... 141 >90%............................................ 597 >95% 1,000 900 3,000 700 13........................ 1 78.4% 441.2 8.4%........................ 1 17.9% 590.9 12.2%................. 1 12.9% 488.0 11.4%.......................... 1 16.8% 361.6 9.2%........................ * 36.0% 87.7 10.6%...................... 1 12.2% 196.4 12.0% * 115

本文件為草擬本所載資料並不完整且或會作出更改須與本文件封面警告一節一併細閱業務下表載列我們主要的專科藥專科藥概述呼吸系統........... 用於治療哮喘普通傷風感冒或其他影響呼吸系統的症狀藥物如鼻減充血劑抗組胺藥支氣管擴張劑粘液溶解劑鎮咳藥及咳嗽祛痰劑心血管科........... 用於治療有關心臟及血管系統的症狀的藥物包括抗心律失常藥物降血脂藥物降壓藥物利尿劑 β 受體阻斷劑鈣通道阻滯劑血管緊張素轉換酶抑制劑及血管緊張素 Ⅱ受體拮抗劑中樞神經系統科.... 用於治療有關大腦脊椎及中樞神經系統科其他部分的症狀的藥物包括止痛藥常規及非典型精神抑制藥抗焦慮藥抗抑鬱藥及催眠藥腸胃科............. 用於治療有關腸胃科包括由口腔至肛門的器官以及消化道的症狀的藥物包括抗酸劑抗腸胃氣脹藥抗潰瘍藥解痙藥止吐藥止瀉藥及輕瀉劑口服糖尿藥......... 用於治療糖尿病的藥物包括磺脲及雙胍類藥物疤痕治療........... 德國秀碧除疤膏專有品牌及二零一五年香港最暢銷疤痕治療產品之一根據弗若斯特沙利文公司佔香港疤痕治療市場 36.0% 的收益 116 說明照片

1,000 900 117

30 60 90............... 12.0 1,580.0 12.4 1,735.0 12.4 1,735.0............. 15.2 294.0 16.0 297.0 16.0 297.0............... 23.2 1,195.0 23.8 1,250.0 23.8 1,250.0 1,000900 76 118

50 359 31.5%29.7% 28.1% 6.3 1,000900 1,000 900 50,000 GSDP ISO9001 SAP SAP 119

A B B A A A B (i) (ii) 75 4 30 25 120

2% 90 60 121

(i) (ii) (iii)(iv).................................... 7 7 7......................... (3).................................... 7 7 4 B (i)(ii) (iii) 122

GMPISO 350 718 30 90 PIC/S GMP 300 123

................ 150,000 140................ 500.................... 5030.............. 30 80..... 210 2,446 2,446 1,783 (1)(3)....... 1,898 1,913 1,598 (%) (2).................. 78 78 90 (4) (1)......... 352,500 307,500 264,375............... 159,162 169,897 119,538 (%) (2).................. 45 55 45 (1)......... 3,311,100 3,311,100 2,654,100............... 2,130,488 2,113,935 1,624,302 (%) (2).................. 64 64 61 (1) 3006 12 124

(2) (3) 250 (4) 18 24 6 20 6 18 GMP 125

PIC/S GMP GMP 250 150 100 16 2 49 GMP GMP PIC/S GMP 30C GMP 138A PIC/S GMP GMPGMP GMP (i) (ii) (iii) GMP GMP 126

127

......................... 60 90 128

..................... 1.0 37.0 1.0 48.0 1.5 55.0 Facebook Acorn Marketing & Research Consultants (Int l) Ltd 129

7 108 130

(i) (ii) (iii) (iv).................................... 7 9 9....................... 2................... (1).................................... 9 9 8 (i)(ii) (iii) (iv) 20% 30% GMP 131

GMPGMP 30 GMP 1 3 (1) (3)....................... 222,206 240,365 358,643............................... 143,245 139,155 151,014 (%) (2)................................ 64 58 42 (1) 52612 (2) (3) 132

6070 40 60 GMP HOKLAS 133

GMP 50,000 134

ERP (i)(ii) 3.5 5.72.8 4.2 5,000 5 135

86 1012 14 18 24 136

(1) (2) (3)........................................................ Powder Pharma Coating Inc. (1) (2) (3) 3 137

138

138 PIC/S GMPGMP PIC/SPIC/S GMP PIC/S GMP..... GMP........ 138A 134 139

137....... 137..... 134..... 138....... 145......... 140

..... GMP... PIC/S GMP 549 PIC/SGMP GMPPIC/S GMPGMP PIC/S GMP GMP PIC (The Convention for the Mutual Recognition of Inspections in Respect of the Manufacture of Pharmaceutical Products) PIC PICPIC (the Pharmaceutical Inspection Co-operation Scheme) PICPIC/SPIC/S PIC/S48(participating authorities) PIC PIC/S PIC/S GMP PIC/SPIC/S PIC/S PIC/S47 PIC/SPIC/S PICGMPGMP PIC/SPIC/SGMP PIC/SGMP PIC/S 141

PIC/SPIC/S PIC/SPIC/SGMPPIC/S PIC/S PIC/S 142

1,555 1,400 1551,567................................................ 692 44.5%..................................... 214 13.8%.......................................... 155 10.0%............................................ 131 8.4%................................................ 111 7.1%................................................ 252 16.2%................................................ 1,555 100.0% 207 98 GMP TVB Online Best Impact Award JPG (BVI) Caring Company Sunday Kiss 2015 Sunday Kiss Top 10 Hong Kong Consumer Product Brands Recommended Brands for Individual Visits 2014 143

Customer s Most Favorable Hong Kong Brands 2013 Jessica Supreme Award JESSICA Mederma for Kids Watson s Health Wellness and Beauty Award Mederma Jessica Baby The Best Seller Jessica Baby Mederma for Kids Jessica Baby Favourite Brands 2013 Hong Kong Top Brand Award 2015 Jessica Baby Premium Chinese Medicine Enterprise Chinese medicine Promotion award 2014 Customer s Most Favorable Hong Kong Brands 2013 Superbrands Hong Kong s Choice Superbrands Roter Customer s Most Favorable Hong Kong Brands 2013 Rowachol & Rowatinex & Customer s Most Favorable Hong Kong Brands 2013 144

354C 145

80 3 B. 2. [ ] [ ] [ ][ ] 146

14* 24,072 31,373 9,435 5937,925 49 123 24 14 * 21,081 GMP 147

.............................. 40(1BA) 24(1) 200,000 20,000 (i) (ii) (a) (b) (c) 10,000 100 153,300 148

40(6) 24 25 25 19 6 19 15 4 4 6 4 6 25 1,249,000 2 19 [ ] 149

(i) (ii) (i) (ii) (i) (ii) (i) (ii) (iii)(iv) 150

30% (i) 70%(ii) 20% 68.8%50.1%52.1%65.0% 29.9% 36.0% 97.0%26.6% 88.8%96.3% 85.0% 85.0% PIC/S 29 23.2% 715.8 13.3% 811.3 151

JPG (BVI) JPG (BVI) JPG (BVI) 3 JPG (BVI) JPG (BVI)JPG (BVI) 97.0%1.4% 1.6% 12.7% 18 29 152

50359 6.3 31.5%29.7% 28.1% 3669 26 86 3824 43.9%41.9% 39.9% 153

GMP PIC/S GMPPIC/ S GMP PIC/S GMPPIC/S GMP B 1 (a) (b) (c) 154

50 10 20 4 20 4 10 9 10 30 20 30 5 10 155

(i) (ii) (i) (ii) (ii) (i) 20 107 (i)(ii)(iii) (iv) 156

157

............................. 926,181 100.0 947,591 100.0 715,830 100.0 811,256 100.0......................... (501,339) (54.1) (562,883) (59.4) (420,693) (58.8) (435,648) (53.7)............................. 424,842 45.9 384,708 40.6 295,137 41.2 375,608 46.3......................... 65,172 7.0 6,005 0.6 2,667 0.4 (1,887) (0.2).................. (97,974) (10.6) (105,061) (11.1) (79,660) (11.1) (104,222) (12.8).............. (169,123) (18.3) (146,810) (15.4) (109,392) (15.3) (113,636) (14.1)......................... 222,917 24.0 138,842 14.7 108,752 15.2 155,863 19.2......................... (5,969) (0.6) (2,707) (0.3) (2,368) (0.3) (2,507) (0.3)....................... 216,948 23.4 136,135 14.4 106,384 14.9 153,356 18.9........................... (32,247) (3.5) (22,157) (2.4) (17,652) (2.5) (25,262) (3.1)................... 184,701 19.9 113,978 12.0 88,732 12.4 128,094 15.8......................... 823,734 88.9 839,011 88.5 632,074 88.3 702,924 86.6........................... 102,447 11.1 108,580 11.5 83,756 11.7 108,332 13.4............................. 926,181 100.0 947,591 100.0 715,830 100.0 811,256 100.0 158

(i) (ii) (iii) (iv).............................................. 292,134 31.5 281,844 29.7 210,761 29.4 227,741 28.1................... 531,600 57.4 557,167 58.8 421,313 58.9 475,183 58.5.................... 823,734 88.9 839,011 88.5 632,074 88.3 702,924 86.6........................... 102,447 11.1 108,580 11.5 83,756 11.7 108,332 13.4............................. 926,181 100.0 947,591 100.0 715,830 100.0 811,256 100.0....................................... 221,302 23.9 324,117 34.2 238,925 33.4 254,471 31.3......................... 602,432 65.0 514,894 54.3 393,149 54.9 448,453 55.3.................... 823,734 88.9 839,011 88.5 632,074 88.3 702,924 86.6.................................................. 42,756 4.6 30,440 3.2 21,433 3.0 38,572 4.8......................... 59,691 6.5 78,140 8.3 62,323 8.7 69,760 8.6....................... 102,447 11.1 108,580 11.5 83,756 11.7 108,332 13.4............................. 926,181 100.0 947,591 100.0 715,830 100.0 811,256 100.0 159

............................. 851,566 91.9 879,109 92.8 663,683 92.7 743,916 91.7............................. 34,078 3.7 28,834 3.0 24,256 3.4 35,404 4.4............................. 21,862 2.4 19,868 2.1 13,369 1.9 17,581 2.2........................... 9,251 1.0 4,683 0.5 4,563 0.6 7,706 0.9............................. 9,424 1.0 15,097 1.6 9,959 1.4 6,649 0.8............................. 926,181 100.0 947,591 100.0 715,830 100.0 811,256 100.0 91.9%92.8% 91.7% 7.1% 5.6% 7.5%......................... 220,123 43.9 236,004 41.9 178,045 42.3 173,803 39.9......................... 154,225 30.8 177,653 31.6 127,929 30.4 140,650 32.3....................... 29,269 5.8 36,196 6.4 27,293 6.5 26,859 6.2....................... 31,083 6.2 36,162 6.4 27,686 6.6 32,695 7.5......................... 23,285 4.6 22,566 4.0 17,016 4.0 19,746 4.5........................... 13,205 2.6 19,907 3.5 15,284 3.6 14,351 3.3....................... 11,173 2.2 11,209 2.0 8,806 2.1 10,099 2.3.................... 18,976 3.9 23,186 4.2 18,634 4.5 17,445 4.0............................. 501,339 100.0 562,883 100.0 420,693 100.0 435,648 100.0 160

20%................... 44,025 47,201 35,609 34,761 15%................... 33,018 35,401 26,707 26,070 10%................... 22,012 23,600 17,805 17,380 +10%.................. (22,012) (23,600) (17,805) (17,380) +15%.................. (33,018) (35,401) (26,707) (26,070) +20%.................. (44,025) (47,201) (35,609) (34,761) 193.0%163.0%165.8% 216.1%......................... 374,103 45.4 333,727 39.8 254,579 40.3 324,740 46.2........................... 50,739 49.5 50,981 47.0 40,558 48.4 50,868 47.0............................. 424,842 45.9 384,708 40.6 295,137 41.2 375,608 46.3 45.9%40.6%41.2% 46.3% 61.1 161

..................... 1,219 1.9 898 15.0 660 24.7 344 (18.2)............ 58 0.1 46 0.8 40 1.5 6 (0.3)................ 2,916 4.5 3,040 50.6 1,381 51.8 1,294 (68.6)......... (691) (1.1) 1,557 25.9 720 27.0 220 (11.7)................. 61,071 93.7 (477) (7.9) (535) (20.1) (4,262) 225.9......................... 599 0.9 941 15.6 401 15.1 511 (27.1)......................... 65,172 100.0 6,005 100.0 2,667 100.0 (1,887) 100.0............................. 44,981 45.9 52,623 50.1 40,017 50.2 44,442 42.6.................. 18,725 19.1 15,051 14.3 11,468 14.4 24,651 23.7......................... 18,520 18.9 15,740 15.0 11,410 14.3 13,694 13.1....................... 7,702 7.9 7,746 7.4 5,755 7.2 6,659 6.4....................... 2,445 2.5 5,724 5.4 4,808 6.1 8,882 8.5....................... 2,054 2.1 2,357 2.2 1,696 2.1 1,529 1.5.......... 3,547 3.6 5,820 5.6 4,506 5.7 4,365 4.2.............................. 97,974 100.0 105,061 100.0 79,660 100.0 104,222 100.0 162

[ ]......................... 112,039 66.2 77,240 52.6 62,028 56.7 56,928 50.1....................... 7,431 4.4 7,375 5.0 5,365 4.9 8,537 7.5....................... 5,211 3.1 9,037 6.2 6,444 5.9 7,870 6.9 [ ]........................... [] [].................. 11,319 6.7 10,770 7.3 6,296 5.8 4,775 4.2....................... 5,816 3.4 5,936 4.0 4,647 4.2 3,901 3.4....................... 1,207 0.7 5,218 3.6 3,602 3.3 3,706 3.3............................. 3,313 2.0 4,648 3.2 3,064 2.8 3,035 2.7......................... 2,505 1.5 2,569 1.7 1,816 1.7 2,123 1.9............................. 3,516 2.1 5,727 3.9 5,090 4.7 2,832 2.5............................. 16,766 9.9 18,290 12.5 11,040 10.0 14,569 12.8............................. 169,123 100.0 146,810 100.0 109,392 100.0 113,636 100.0 [ ] [ ] 163

............... 10,723 14,265 10,234 12,287...... 317 172 137 81 11,040 14,437 10,371 12,368................... (5,071) (11,730) (8,003) (9,861)......................... 5,969 2,707 2,368 2,507..................... 32,829 24,446 20,272 22,974..................... (582) (2,289) (2,620) 2,288......................... 32,247 22,157 17,652 25,262 16.5% 14.9%16.3%16.6% 16.5% 164

184.7 114.0 88.7 128.1 19.9%12.0%12.4% 15.8% 715.8 95.5 13.3% 811.3 70.8 24.7 632.1 11.2%702.9(i) 210.8 227.7(ii)421.3 475.2 83.7 29.5%108.4(i) (ii) (iii) 420.7 15.03.6% 435.7 (i)12.7 (ii)5.0 58.8% 53.7% 165

295.180.5 27.3% 375.6 41.2%46.3% 1.9 2.7 (i) 3.7 (ii)0.5 79.6 24.6 30.9% 104.2 (i)(ii)4.4 (iii) 4.1 109.4 4.23.8% 113.6 (i) [ ] [ ] [] (ii) 3.2 5.1 108.8 47.143.3%155.9 2.4 0.1 4.2% 2.5 2.0 1.9 166

106.4 47.044.2%153.4 17.7 7.6 42.9%25.3 16.6% 16.5% 88.7 39.444.4%128.1 12.4% 15.8% 926.221.42.3% 947.6 15.3 6.1 823.7 15.31.9% 839.0 531.6 25.6 4.8% 557.2 292.1 281.8 102.56.1 6.0% 108.6 501.3 61.6 12.3%562.9 (i) 23.4(ii) 167

15.9 (iii)6.9 (iv) 6.7 (v)5.1 54.1%59.4%PIC/S 424.9 40.2 9.5% 384.7 45.9% 40.6% 65.2 59.2 90.8%6.0 61.1 1.6 0.7 98.0 7.07.0% 105.0 (i) 7.6 (ii)3.3 3.7 169.1 22.313.2%146.8 34.4 34.8 (i) 3.8 (ii) 4.0 222.9 84.037.7%138.9 168

6.0 3.3 55.0%2.7 299.6 475.6 10.7 14.3 5.1 11.7 216.9 80.7 37.2%136.2 32.2 10.0 31.1%22.2 14.9%16.3% 61.1 184.7 70.738.3% 114.0 19.9% 12.0%(i)(ii) 61.1 [ ] [ ] [ ] 12 169

........ 150,272 161,754 117,857 175,957........ (126,529) (390,971) (318,653) (96,774) (8,747) 160,853 117,043 (15,929)................. 14,996 (68,364) (83,753) 63,254................. 116,778 131,492 131,492 63,005................ (282) (123) 52 311................. 131,492 63,005 47,791 126,570 176.0 153.4 47.2 34.7 (i)24.8 (ii) 22.7 12.8 117.9 106.4 39.9 30.5 (i)27.1 (ii)10.7 161.8 136.1 52.9 26.5 170

150.3 216.9 44.0 61.1 35.4 19.0 16.7 96.8 97.2 318.7 (i)284.9 (ii) 33.9 391.0 (i)339.6 (ii) 33.9 (iii) 13.76% 17.8 126.5 (i)200.4 (ii) 13.76% 10.5 90.3 15.9 (i)225.6 (ii)11.7 (iii)9.6 233.3 171

117.0 (i)330.5 (ii) 15.6(i) 216.5 (ii)9.7 160.9 (i)530.1 (ii) 22.5 (i)365.2 (ii)13.6 (iii) 9.6 8.7 (i)80.6 (ii)10.2 (i)48.7 (ii) JPG (BVI)2,00028.0 (iii)11.0 B 21 200.4 339.6 284.997.2........ 182,103 330,293 283,232 71,737................ 18,288 9,319 1,665 25,454......................... 200,391 339,612 284,897 97,191 123.2 172

......................... 160,368 169,087 191,820 194,986.......... 142,740 148,795 171,885 167,400.............. 10,340 5,895 705 8,107............ 131,492 70,258 126,570 75,283................ 444,940 394,035 490,980 445,776.......... 135,203 90,152 110,420 90,222.... 296,008 475,629 476,703 449,593................ 2,342 2,251 1,235 705............ 43,940 79,592 70,012 61,273............ 2,780................ 8,641 2,614 23,552 17,293................ 488,914 650,238 681,922 619,086................ 43,974 256,203 190,942 173,310 173.3 445.8619.1 190.9 17.6 190.9 491.0681.9 256.2 65.3 (i) 56.3 (ii)23.1 (iii)22.7 (i)20.9(ii) 20.3 256.2 394.0650.2 44.0 212.2 (i) 179.6 (ii)61.2 (iii)35.7 45.1 44.0 444.9488.9 159.0311.0 261.8 [ ] 173

................................... 77,809 80,030 81,851................................... 20,395 16,716 15,775................................... 62,164 72,341 94,194..................................... 160,368 169,087 191,820 160.4 5.4% 169.1 13.4% 191.8............................. 111 107 114 365 111 107 107 114 48.5%............................ 110,316 110,120 133,313 (1)........................... 2,758 3,048 2,063 (2)............................. 314 342.......................... 29,352 35,285 36,509..................................... 142,740 148,795 171,885 (1) 174

(2) 30 60 90 6090 110.3 110.1 110.1 21.1%133.3............................... 51,390 50,709 78,887............................... 49,216 58,151 53,736............................... 9,710 1,260 690..................................... 110,316 110,120 133,313........................ 62,914 69,849 94,428.......................... 28,126 27,440 29,024.......................... 8,802 10,815 8,329.......................... 10,474 2,016 1,532..................................... 110,316 110,120 133,313 175

..................... 44 42 41 365 68.2% 29.4 20.1% 35.3 1.6 2.3 35.3 3.4% 36.5 [ ] 1.6............................ 29,605 24,679 26,131.......................... 30,362 30,422 45,327............................... 41,822 9,755 7,456.................. 32,732 17,707 19,781................................. 682 7,589 11,725..................................... 135,203 90,152 110,420 30 90 29.6 16.6% 24.7 24.7 5.7% 26.1 176

................................. 15,735 13,438 15,401............................... 12,905 10,972 10,333............................... 965 269 397..................................... 29,605 24,679 26,131..................... 21 18 16 365 21 18 16 84.3% 30.4 49.0% 45.3 41.876.6% 9.8 9.8 23.5% 7.5 32.7 45.9% 17.7 17.8 17.7 11.9% 19.8 177

[ ] [ ] 12....................... 7,253 3,403...... 137,037 157,364 214,908 214,639........ 158,971 311,012 261,795 231,551 296,008 475,629 476,703 449,593..................... 2,342 2,251 1,235 705 (1)................ 43,940 79,592 70,012 61,273................. 2,780 345,070 557,472 547,950 511,571....... 3,568..................... 2,972 867 560 535 6,540 867 560 535 351,610 558,339 548,510 512,106 (1) 351.6 58.8% 558.3 558.3 1.8% 548.5 548.5 6.6%512.1 178

................. 6.54% 8.4% 13,675 6.54% 8.4% 5,886 3.15% 6.54% 7,667................... 2% 9.15% 5,314 2% 9.15% 3,118 2% 9.15% 1,795............. 2% 2,780 21,769 9,004 9,462................. 1.69% 3.98% 285,901 1.7% 5.25% 469,743 1.69% 5.25% 469,036................... 307,670 478,747 478,498................. 296,008 475,629 476,703 449,593..................... 3,568................................ 299,576 475,629 476,703 449,593.................................... 128,736 125,524 121,625............................................ 54,264 52,885 51,540............................. 71,122 73,141 73,516....................................... 63,175................................................ 254,122 251,550 309,856 179

263.1 444.2 454.2 441.5 [ ] 461.7 199.0 180

....................... 195,075 25,413 14,275................................... 39,190 40,725 49,061.......................... 33,910 39,245 31,788..................................... 73,100 79,970 80,849 181............................. 314 342..................................... 314 342........................ 43,940 79,592 70,012........................... 2,780..................................... 46,720 79,592 70,012

(i) (ii)(iii) [ ] 20.0 2% 92,000 25,000 [ ] [ ] B 28(i) (ii) 8%21% 1%237,000 343,00017,000 10%11% 0%135,000 51,000 B 25(d) 182

10 249,000 431,000 331,000 B 25(c) 8.7%8.3% 10.9% 28.4%25.1% 25.5% B 25(b) (%) (1).............................................. 45.9 40.6 (2).............................................. 19.9 12.0 (3).......................................... 20.7 10.6 (4)........................................ 12.8 6.4 (5).................................... 0.91 0.61 0.72 (6).................................... 0.58 0.35 0.44 (7).............................. 18.3% 40.3% 30.9% 183

(1) 100% (2) 100% (3) 100% (4) 100% (5) (6) (7) 100% 20.7% 10.6% 61.1 12.8% 6.4% 61.1 0.91 0.61(i)(ii) 0.61 0.72 (i)(ii)(iii) 0.58 0.350.44 18.3% 40.3%(i)(ii) 40.3% 30.9% [ ] [][][][] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] 184

15.022.8200.2 [ ] 7 185

(1)............................ 468,257.......................... 21,740............................................... (164,800).......................... 325,197................................ (321,779)................................ 3,418 (1) 7 [ ] [ ] 13.13 13.19 [ ] (1) [ ] [ ] (2) (3) [ ] [ ].......... 673,509 [] [] [] [ ] [ ].......... 673,509 [] [] [] 186

(1) 1,076,263,000 (i) 424,093,000 (ii)21,339,000 (2) [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ][ ] [ ] [ ] [ ] [ ] (3) [] (4) JPG (BVI)200,200,000 (5) 7 7 321.8 187

..... 53..... 40 *... 54 *... 57..... 59 188

..... 52..... 52 * 44 54 PIC/S PIC/S 43 189

.... 43.... 53.... 32.... 64.... 32 53 28 (Cardiff University) (The Royal Pharmaceutical Society of Great Britain) 190

[ ] 14 A.2.1 [ ] 40 12 54 30 1321 95 878 1168 182 687 (University of Manchester) 191

57 2277 83151250 33661418 8305 8059 AS & T Consultants Limited 291(6) 59 30 Glaxo Canada Inc. 2 3 192

52 52 TGS GlobalAITIA (HK) CPA LIMITED 16 Hodgson Impey Cheng 952 [ ] [ ] [ ] 13.51(2) 44 193

54 PIC/S 15 General Pharmaceutical Council 43 20 1253 1121 638 1259 43 15 194

53 20 32 64 32 10 195

[ ] 3.21 [ ] [ ] [ ] 3.25 [ ] [ ] (i) (ii) (iii) []A.5.1 [ ] 68.3 27.6 9.1 196

74.3 32.913.4 17.0 B 6 7 C. 2. (c) [ ] 3A.19 [ ] 3A.23 i. ii. iii. [][] iv. [ ] [ ] 197

[ ]............................................. 5,000,000,000 50,000,000.......................... 1,312,500,000 13,125,000 [ ]........................ [ ] []............................................. [ ] [] [ ] [ ] [ ] (i)(ii)(iii)(iv) (v) 2. 2.5 2. 2.4 [ ] D. 1. 198

[ ] [] [ ] (a) (b) (c) (i) [ ] [ ] 20% (ii) (1) (2) (3) A. 5. [ ] [] [ ] [ ] [ ] 10% [ ] [ ] [] A. 6. 199

(i) (ii) (iii) B. 5. 200

[ ][ ]Kingshill Longjin [ ]% Kingshill The Kingshill TrustTrust CoThe Kingshill Trust Longjin 75% Kingshill Longjin LongjinLongjin KingshillLongjin [ ]%[ ] [ ] KingshillLongjin [ ] 8.10 [] 7313 3[ ] 201

[ ] (a) (b) (c) (d) (i)(ii) B 28[ ] B 19[] 202

(7) (6) 5% [ ] [ ] (a) [ ] (b) 30% 203

[ ] [ ] 14 [ ] 204

[ ] [ ] XV2 3 10% [ ] (1) Queenshill (2)......... [ ] [] Kingshill (3)........... [ ] [] Longjin (3)............ [ ] [] Trust Co 4.......... [ ] [] UBS Trustees (BVI) Limited 4......... [ ] [] (3)........... [ ] [] (2)(4).......... [ ] [] (1) [ ] (2) The Jacobson Pharma (PTC) Limited Queenshill The Jacobson Pharma (PTC) LimitedQueenshillThe Jacobson Pharma (PTC) Limited[ ]Queenshill (3) Kingshill Longjin Kingshill The Kingshill Trust Trust CoThe Kingshill TrustLongjin 75% (4) UBS Trustees (BVI) Limited The Kingshill TrustUBS Nominee Limited Trust CoTrust CoKingshillKingshill[] The Kingshill Trust UBS Trustees (BVI) LimitedTrust Co Kingshill Kingshill[ ] [ ] [ ] XV2 3 10% 205

[ ] [ ] [ ] [ ] [ ] [ ] [ ][] [ ] [ ] [ ] [ ] [ ][] [ ] [ ] [ ][ ] [ ][ ] [ ][ ] [ ][ ] [ ] [ ][ ] [ ] [ ] [ ][] [ ] 206

[ ] [][][[]][][] [][[]][][][[]] [][][][[ ] ][ ] [ ] [ ] [ ] [ ] (i) [[] ] [ ] [[] ][ ] (ii) [[] ] [ ] [[] ][ ] (iii) [[] ] [ ] [[] ][ ] [ ] [ ] [ ] [ ] [ ] [][][] 207

[ ] [ ] 208

[ ] [ ] 209

[ ] [ ] 210

[ ] [ ] 211

[ ] [ ] 212

[ ] [ ] 213

[ ] [ ] 214

[ ] [ ] 215

[ ] [ ] 216

[ ] [ ] 217

[ ] [ ] 218

[ ] [ ] 219

[ ] [ ] 220

[ ] [ ] 221

[ ] [ ] 222

[ ] [ ] 223

[ ] [ ] 224

[ ] [ ] 225

[ ] [ ] 226

[ ] [ ] 227

[ ] [ ] 228

[ ] [ ] 229

[ ] [ ] 230

[ ] [ ] 231

[ ] [ ] 232

[ ] [ ] 233

[ ] [ ] 234

[ ] [ ] 235

[ ] [ ] 236

[ ] [ ] 237

[ ] [ ] 238

[ ] [ ] 239

[ ] [ ] 240

[ ] [ ] 241

10 8 [ ] [ ][ ] [ ] B1(b) B 1(b) B I-1

[ ] [ ] [ ] [ ] 3.340 B 1(b) 2410 I-2

A 1 B...................... 2 926,181 947,591 715,830 811,256.................. (501,339) (562,883) (420,693) (435,648)...................... 424,842 384,708 295,137 375,608.......... 3 65,172 6,005 2,667 (1,887)........... (97,974) (105,061) (79,660) (104,222)....... (169,123) (146,810) (109,392) (113,636).................. 222,917 138,842 108,752 155,863.................. 4(a) (5,969) (2,707) (2,368) (2,507)................ 4 216,948 136,135 106,384 153,356.................... 5(a) (32,247) (22,157) (17,652) (25,262)............ 184,701 113,978 88,732 128,094.......... 677 (110) 52 (2,609)............. 677 (110) 52 (2,609)... 185,378 113,868 88,784 125,485......... 172,357 101,904 78,030 121,529................ 12,344 12,074 10,702 6,565........ 184,701 113,978 88,732 128,094......... 173,034 101,794 78,082 118,920................ 12,344 12,074 10,702 6,565... 185,378 113,868 88,784 125,485................ 8 I-3

2 B............... 10 412,878 610,690 771,912....................... 11 54,691 53,294 51,932....................... 12 372,917 422,924 424,093..................... 13 168,083 220,778 121,383.................. 20 3,300 3,490 4,320 1,011,869 1,311,176 1,373,640........................... 14 160,368 169,087 191,820............ 15 142,740 148,795 171,885................ 10,340 5,895 705.............. 17 131,492 70,258 126,570 444,940 394,035 490,980............ 18 135,203 90,152 110,420...... 19 296,008 475,629 476,703.................. 19 2,342 2,251 1,235 16 43,940 79,592 70,012............ 16 2,780.................. 8,641 2,614 23,552 488,914 650,238 681,922 43,974 256,203 190,942 967,895 1,054,973 1,182,698............ 19 3,568.................. 19 2,972 867 560.................. 20 44,368 47,471 50,616 50,908 48,338 51,176....................... 916,987 1,006,635 1,131,522........................... 21 2 2 2........................... 22 877,892 957,341 1,076,261..................... 877,894 957,343 1,076,263..................... 39,093 49,292 55,259....................... 916,987 1,006,635 1,131,522 I-4

3 B 21 22(b) 22(a) 22(c).................... 2 50,003 66,428 7,575 573,037 697,045 50,846 747,891................................. 172,357 172,357 12,344 184,701............................ 677 677 677........................ 677 172,357 173,034 12,344 185,378................................. 21 28,002 28,002 28,002........................ 9 (15,000) (15,000) (15,000)....... (1,059) (1,059).......................... 24 (5,187) (5,187) (23,038) (28,225) 28,002 (5,187) (15,000) 7,815 (24,097) (16,282)................ 2 78,005 61,241 8,252 730,394 877,894 39,093 916,987.................... 2 78,005 61,241 8,252 730,394 877,894 39,093 916,987................................. 101,904 101,904 12,074 113,978............................ (110) (110) (110)........................ (110) 101,904 101,794 12,074 113,868........................ 9 (22,828) (22,828) (22,828)....... (992) (992).......................... 24 483 483 (883) (400) 483 (22,828) (22,345) (1,875) (24,220)................ 2 78,005 61,724 8,142 809,470 957,343 49,292 1,006,635.................... 2 78,005 61,724 8,142 809,470 957,343 49,292 1,006,635................................. 121,529 121,529 6,565 128,094............................ (2,609) (2,609) (2,609)........................ (2,609) 121,529 118,920 6,565 125,485....... (598) (598).............. 2 78,005 61,724 5,533 930,999 1,076,263 55,259 1,131,522 I-5

B 21 22(b) 22(a) 22(c) 2 78,005 61,241 8,252 730,394 877,894 39,093 916,987................................. 78,030 78,030 10,702 88,732............................ 52 52 52........................ 52 78,030 78,082 10,702 88,784....... (992) (992).......................... 24 483 483 (883) (400) 483 483 (1,875) (1,392).............. 2 78,005 61,724 8,304 808,424 956,459 47,920 1,004,379 I-6

4 B................ 216,948 136,135 106,384 153,356.............. 4(c) 43,996 52,945 39,885 47,224...... 3 (61,071) 477 535 4,262................ 4(a) 5,969 2,707 2,368 2,507..... 3 (58) (46) (40) (6)............ 3 (2,916) (3,040) (1,381) (1,294)............ 1,875 1,908 1,428 1,469.............. 204,743 191,086 149,179 207,518.................. (16,712) (4,484) (10,671) (22,733)............ 1,739 (2,731) (27,120) (24,812)............ (4,067) 4,359 7,339 12,811........... 185,703 188,230 118,727 172,784...... (35,431) (26,476) (870) 3,173..... 150,272 161,754 117,857 175,957..... (200,391) (339,612) (284,897) (97,191)................ 90,277 671 528 411.............. 24 (10,473) (18,152) (400).................... 23 (6,000) (33,924) (33,924).................. 58 46 40 6..... (126,529) (390,971) (318,653) (96,774) I-7

B................ (2,817) (2,345) (1,766) (1,699)... 48,715 530,132 330,483 233,293....... (80,633) (365,190) (216,539) (225,623)............ 11,024 22,452 15,582 (9,580)............. (10,179) (13,576) (9,725) (11,722)......... 21 28,002.................. (1,800) (9,628)..... (1,059) (992) (992) (598).................... (8,747) 160,853 117,043 (15,929)........ 14,996 (68,364) (83,753) 63,254.............. 116,778 131,492 131,492 63,005........... (282) (123) 52 311.............. 17 131,492 63,005 47,791 126,570 I-8

B 1 (a) B 31 [ ] (b) Jacobson Pharma Group (BVI) LimitedJPG (BVI) [ ][] [ ] JPG (BVI) JPG (BVI) 3 JPG (BVI)JPG (BVI) JPG (BVI) I-9

Citi-Ascent Limited Jacobson Group Management Limited Jacobson Group Treasury Limited Jacobson Pharma (China) Limited 160,000 100% (ii) 108,600,000 100% (i)(v) 8,750,000 100% (ii) 10,000 100% (iii) 1,100,000 100% (ii) 1 100% (viii) 10,000 100% (iii) 18,000,009 89.31% (ii) 440,000 100% (ii) 10,000 100% 10,000 100% 26,628,000 100% 10,000 100% (vii) 10,000 100% (iv) 48,193,657 100% (ii) 10,000 100% (iv) 500,000 55.20% (ii) (ii) (iii) (ii) Li Chung Shing Tong (S) Pte Limited 50,000 1 100% (vi) I-10

10,000 55.20% (iii) 10,000,000 100% (ii) 10,000 100% (ii) 3,000,000 100% (ii) 1,000,000 100% (ii) 10,000 100% (viii) 10,000 100% (iv) 46,800 100% (ii) 10,000 100% (iv) 5,000 100% (ii) 661,650 100% (ii) (i) (ii) (iii) Jacobson Group Treasury Limited (iv) (v) (vi) M E Lim & Co (vii) (viii) I-11

19(a) 158,971,000 311,012,000 261,795,000 (c) 29 (d) (e) 1(n) 1(o) I-12

(f) (i)(ii) (i) (ii) (ii) (i) 1(k)(ii) (g) 1(k)(ii) 50 10 20 4 20 4 10 9 10 I-13

(h) 1(k)(ii) (i) 1(k)(ii) 30 20 30 5 10 1(k)(ii) 1(v)1(k) (ii) (j) I-14

(i) (ii) 1(g)1(k)(ii) (iii) 20107 (k) (i) I-15

(ii) I-16

(l) (m) 1(k)(i) (n) (o) I-17

(p) (q) (r) I-18

(s) I-19

(t) (i) (ii) (iii) (u) (v) I-20

(w) (1) (i) (ii) (iii) (2) (i) (ii) (iii) (iv) (v) (vi) (1) (vii) (1)(i) (x) I-21

2 (a) (b) EBITDA EBITDA I-22

(i).......... 823,734 839,011 632,074 702,924 102,447 108,580 83,756 108,332 926,181 947,591 715,830 811,256 EBITDA............ 180,054 168,270 127,734 184,408 25,746 23,471 20,863 18,673 205,800 191,741 148,597 203,081 I-23

(ii).......... 926,181 947,591 715,830 811,256............. 205,800 191,741 148,597 203,081.......... 58 46 40 6................. 61,055................... (43,996) (52,945) (39,885) (47,224)..................... (5,969) (2,707) (2,368) (2,507).............. 216,948 136,135 106,384 153,356 (iii)................. 851,566 879,109 663,683 743,916......................... 34,078 28,834 24,256 35,404......................... 21,862 19,868 13,369 17,581....................... 9,251 4,683 4,563 7,706......................... 9,424 15,097 9,959 6,649 926,181 947,591 715,830 811,256 I-24

.......................... 956,646 1,261,884 1,331,674.................................. 51,919 45,800 37,644................................ 4 2 2 1,008,569 1,307,686 1,369,320 (iv) 10% 292,134,000 281,844,000 210,761,000 227,741,000 3..................... 1,219 898 660 344............ 58 46 40 6................ 2,916 3,040 1,381 1,294......... (691) 1,557 720 220................. 61,071 (477) (535) (4,262)......................... 599 941 401 511 65,172 6,005 2,667 (1,887) 61,055,000 I-25

4 (a)........... 10,723 14,265 10,234 12,287............... 317 172 137 81 11,040 14,437 10,371 12,368 *....... (5,071) (11,730) (8,003) (9,861) 5,969 2,707 2,368 2,507 * 3.17%3.07% 3.05% 3.13% (b)..... 302,350 309,386 230,498 241,438.. 10,205 12,907 9,228 10,423 312,555 322,293 239,726 251,861 5% 30,000 25,000 I-26

20% (c) 11...... 1,481 1,397 1,052 1,047 12...... 10,434 13,322 10,040 10,800 10............. 32,081 38,226 28,793 35,377............... 10 51 16 49............... 38,644 49,557 35,344 44,031.............. 4,059 4,592 2,930 2,886.............. 516 680 415 431.......... 3,516 5,727 5,090 2,832 # 14(b)...... 501,339 562,883 420,693 435,648 # 211,660,000 249,435,000181,749,000 200,503,000 4(b) I-27

5 (a)............... 32,609 26,589 21,976 23,233....................... 220 (2,143) (1,704) (259) 32,829 24,446 20,272 22,974........ (582) (2,289) (2,620) 2,288 32,247 22,157 17,652 25,262 (b)................... 216,948 136,135 106,384 153,356................. 35,660 22,389 17,375 24,902.......... 2,251 2,052 837 3,372.......... (7,334) (301) (541) (531).......... (224) (466) (173) (30)........ 1,299 508 1,856 (2,344)................... 375 118 2 152....................... 220 (2,143) (1,704) (259)................ 32,247 22,157 17,652 25,262 (i) (ii) 16.5% I-28

6................... 29,154 36,435 192 65,781................... 350 350................... 2,165 15 2,180 350 31,319 36,435 207 68,311................... 21,921 3,315 215 25,451................... 250 250................... 1,916 18 1,934 250 23,837 3,315 233 27,635................... 17,798 160 17,958................... 188 188................... 1,032 13 1,045 188 18,830 173 19,191 I-29

................... 7,913 164 8,077................... 188 188................... 783 14 797 188 8,696 178 9,062....................................................................................... 7 7 6.............. 4,482 4,820 3,602 5,243..................... 1,768 605................ 49 67 50 65 6,299 5,492 3,652 5,308 I-30

1,000,0001,500,000... 3 3 1,500,0012,000,000... 1 2 1 2,000,0012,500,000... 2 1 8 1(b) 9 15,000,000 22,828,000 10.......... 79,633 168,489 76,170 9,780 28,042 81,994 444,108........................... 17,773 20,968 1,076 5,375 124,777 169,969........................... (16,031) (2,279) (4,141) (2,119) (5,716) (30,286)....................... 463 1,357 40 9 186 2,055...... 64,065 185,340 93,037 8,746 27,887 206,771 585,846.......... 20,046 70,582 38,578 5,853 20,639 155,698....................... 3,045 15,691 8,623 1,724 2,998 32,081..................... (2,844) (2,027) (4,080) (1,389) (5,707) (16,047)....................... 190 880 31 8 127 1,236...... 20,437 85,126 43,152 6,196 18,057 172,968...... 43,628 100,214 49,885 2,550 9,830 206,771 412,878 I-31

.......... 64,065 185,340 93,037 8,746 27,887 206,771 585,846........................... 16,728 12,036 2,863 3,526 201,737 236,890 23.......... 79 218 297........................... (4,320) (1,130) (253) (5,703)....................... (2) (2)...... 64,065 197,827 104,159 11,356 31,413 408,508 817,328.......... 20,437 85,126 43,152 6,196 18,057 172,968....................... 2,815 18,484 11,653 1,502 3,772 38,226..................... (3,548) (770) (237) (4,555)....................... (1) (1)...... 23,252 100,062 54,034 7,461 21,829 206,638...... 40,813 97,765 50,125 3,895 9,584 408,508 610,690.......... 64,065 197,827 104,159 11,356 31,413 408,508 817,328........................... 10,497 17,339 2,036 11,207 162,941 204,020........................... (6,541) (7,282) (767) (3,130) (17,720)........................... 45,531 42,956 17,286 (105,773)....................... (2,353) (4,301) (107) (23) (667) (7,451).... 61,712 243,013 157,065 12,602 56,109 465,676 996,177.......... 23,252 100,062 54,034 7,461 21,829 206,638....................... 2,093 17,452 10,005 1,211 4,616 35,377..................... (6,228) (2,922) (767) (3,130) (13,047)....................... (840) (3,212) (90) (23) (538) (4,703).... 24,505 108,074 61,027 7,882 22,777 224,265.... 37,207 134,939 96,038 4,720 33,332 465,676 771,912 19(a)(i) 1 5 6,286,000 465,000 818,000 6,718,000 4,953,000 5,045,000 I-32

11............................ 79,698 63,995 63,995.................................. (16,031).............................. 328 (517)....... 63,995 63,995 63,478............................ 8,792 9,304 10,701........................ 1,481 1,397 1,047............................ (1,064).............................. 95 (202)....... 9,304 10,701 11,546....... 54,691 53,294 51,932 19(a)(i) 12.......... 108,507 1,300 49,960 123,787 124,168 407,722........................... 2,808 9,000 11,808...... 108,507 1,300 52,768 132,787 124,168 419,530.......... 15,523 20,656 36,179....................... 4,226 6,208 10,434...... 19,749 26,864 46,613 108,507 1,300 52,768 113,038 97,304 372,917 I-33

.......... 108,507 1,300 52,768 132,787 124,168 419,530........................... 1,220 30,580 31,800 23.......... 2,630 13,817 15,082 31,529...... 108,507 2,520 55,398 146,604 139,250 30,580 482,859.......... 19,749 26,864 46,613....................... 4,772 6,774 1,776 13,322...... 24,521 33,638 1,776 59,935...... 108,507 2,520 55,398 122,083 105,612 28,804 422,924.......... 108,507 2,520 55,398 146,604 139,250 30,580 482,859........................... 7,380 4,247 342 11,969.... 108,507 2,520 55,398 153,984 139,250 4,247 30,922 494,828.......... 24,521 33,638 1,776 59,935....................... 3,665 5,222 1,913 10,800.... 28,186 38,860 3,689 70,735.... 108,507 2,520 55,398 125,798 100,390 4,247 27,233 424,093 I-34

.............................. 96,779 96,779 96,779................................ 11,728 11,728 11,728 108,507 108,507 108,507.............................. 2,808 2,808 2,808................................ 49,960 52,590 52,590 52,768 55,398 55,398................................ 13% 61% 17% 59% 14% 55%................................ 3% 3% 3%................................ 14% 18% 14% 15% 14% 15% I-35

13............... 71,122 73,141 73,516............... 96,961 147,637 47,867 168,083 220,778 121,383 19(a)(i) 14 (a)................................ 77,809 80,030 81,851................................ 20,395 16,716 15,775................................ 62,164 72,341 94,194 160,368 169,087 191,820 (b)............ 491,284 555,162 415,560 429,468..................... 10,055 7,721 5,133 6,180 501,339 562,883 420,693 435,648 I-36

15......................... 110,316 110,120 133,313......................... 2,758 3,048 2,063 28(b).......................... 314 342....................... 29,352 35,285 36,509 142,740 148,795 171,885 14,370,000 14,568,000 16,806,000 19(a)(i) 63,175,000 0 90 25(a) (a)............................ 51,390 50,709 78,887............................ 49,216 58,151 53,736............................ 9,710 1,260 690 110,316 110,120 133,313 I-37

(b)..................... 62,914 69,849 94,428....................... 28,126 27,440 29,024....................... 8,802 10,815 8,329....................... 10,474 2,016 1,532 110,316 110,120 133,313 16 (a) [ ][ ] (b) 2% 17....................... 131,492 70,258 126,570 19...................... (7,253).......................... 131,492 63,005 126,570 I-38

18......................... 29,605 24,679 26,131....................... 30,362 30,422 45,327.......................... 41,822 9,755 7,456............... 32,732 17,707 19,781.............................. 682 7,589 11,725 135,203 90,152 110,420.............................. 15,735 13,438 15,401......................... 12,905 10,972 10,333............................ 965 269 397 29,605 24,679 26,131 I-39

19 17 19(a)............... 7,253 19(a).......................... 137,037 157,364 214,908 19(a)............... 158,971 311,012 261,795............. 296,008 475,629 476,703 19(b)............... 2,342 2,251 1,235 16(a) 28(c).... 43,940 79,592 70,012 16(b) 28(c)............. 2,780 345,070 557,472 547,950 19(a).......................... 3,568 19(b)............... 2,972 867 560 6,540 867 560 351,610 558,339 548,510 (a) (i) 17............... 7,253.............................. 282,490 224,327 210,457.............................. 17,086 244,049 266,246 299,576 475,629 476,703 I-40

440,045,000 606,581,000 678,441,000 318,042,000 487,096,000 486,604,000 [ ][]...................... 128,736 125,524 121,625.............................. 54,264 52,885 51,540............... 71,122 73,141 73,516......................... 63,175 254,122 251,550 309,856 (ii)................... 296,008 475,629 476,703....................... 3,568 299,576 475,629 476,703 25(b) I-41

................... 7,253............................ 137.037 157,364 214,908 137,037 164,617 214,908....................... 105,522 106,315 124,221....................... 50,342 198,983 132,532................................ 6,675 5,714 5,042 162,539 311,012 261,795 299,576 475,629 476,703 (b)........................ 2,342 2,520 2,251 2,361 1,235 1,285............... 2,244 2,349 635 680 298 373............... 728 805 232 327 262 328 2,972 3,154 867 1,007 560 701 5,314 5,674 3,118 3,368 1,795 1,986......... (360) (250) (191)................. 5,314 3,118 1,795 I-42

20 (a)........ 8,541 34,943 (1,852) 41,632............. 2,571 (1,705) (1,448) (582)..................... 18 18.... 11,130 33,238 (3,300) 41,068........ 11,130 33,238 (3,300) 41,068............. 1,455 2,897 (6,641) (2,289) 23........ 5,202 5,202.... 12,585 41,337 (9,941) 43,981........ 12,585 41,337 (9,941) 43,981............. 6,524 (1,208) (3,028) 2,288..................... 27 27.. 19,136 40,129 (12,969) 46,296........................ (3,300) (3,490) (4,320)........................ 44,368 47,471 50,616 41,068 43,981 46,296 (b) 1(r) 12,108,000 15,234,000 19,945,000 I-43

21 JPG (BVI) 0.01 5,000 390 5,000 390 5,000 390............... 20 2 22 2 22 2................. 2............... 22 2 22 2 22 2 JPG (BVI)28,002,000 2,0000.0128,002,000 JPG (BVI) JPG (BVI) 22 (a) (b) JPG (BVI) JPG (BVI) (c) 1(u) I-44

(d) 23 38,592,000 17,585,0003,132,000 5,100,000 1,180,000................................................. 297......................................................... 31,529............................................................. 4,235.............................................. 3,994.................................................. 44................................................ 4,668.............................................. (468).................................................... (505).................................................... (5,202)............................................ 38,592.................................................... 38,592...................................... (4,668) 33,924 449,000 I-45

24 13.76% 28,225,000 75% 88.76% 23,038,000 5,187,000 167,428,000......................... 113,569...................................... 23,038.................................................... 9,909.................... 146,516 0.55% 400,000 88.76% 89.31% 883,000 483,000 160,571,000......................... 146,516...................................... 883.................................................... 4,172....................................................... (7,828).................... 143,743 I-46

25 (a) 8.7%8.3% 10.9% 28.4% 25.1% 25.5% 15 (b) 19 16 19 I-47

1 1 2 2 5 5........... 130,721 105,414 55,441 8,355 299,931 283,161........ 13,448 3,684 17,132 16,415..................... 2,805 2,805 2,780 146,974 109,098 55,441 8,355 319,868 302,356............ 283,161 (130,721) (105,414) (55,441) (8,355) (16,770) 283,161 16,253 3,684 303,098 302,356 1 2 1 2 5 5........... 165,914 115,556 206,664 7,422 495,556 464,808........ 3,684 3,684 3,568 169,598 115,556 206,664 7,422 499,240 468,376............ 464,807 (165,914) (115,556) (206,664) (7,422) (30,749) 464,807 3,684 468,491 468,376 I-48

1 1 2 2 5 5........... 225,771 131,049 137,362 6,350 500,532 476,517........ 189 189 186 225,960 131,049 137,362 6,350 500,721 476,703............ 476,517 (225,771) (131,049) (137,362) (6,350) (24,015) 476,517 189 476,706 476,703 (c) (i) (i)............ 6.54% 8.4% 13,675 6.54% 8.4% 5,886 3.15% 6.54% 7,667............. 2% 9.15% 5,314 2% 9.15% 3,118 2% 9.15% 1,795............... 2% 2,780 21,769 9,004 9,462............ 1.69% 3.98% 285,901 1.7% 5.25% 469,743 1.69% 5.25% 469,036............. 307,670 478,747 478,498....... 7% 2% 2% (ii) 10 249,000 431,000 331,000 I-49

(d) (i)........ 1,720 970 33 848 1,538 1,833 1,564 151........ (3,406) (3,931) (1,385) (2,083) (3,173) (461) (1,464) (3,294) (8)............... (1,686) (2,961) (1,352) (1,235) (1,635) (461) 369 (1,730) 143 I-50

(ii)............................ 8% (237) 21% (343) 1% (17) (8)% 237 (21)% 343 (1)% 17............................ 10% (135) 11% 51 0% (10)% 135 (11)% (51) 0% (e) 26.......................... 195,075 25,413 14,275 I-51

27 1...................................... 39,190 40,725 49,061 1 5.............................. 33,910 39,245 31,788 73,100 79,970 80,849 1 5 28 (a).............. 92 25 25 I-52

(b).............................. 314 342 (c).......................... 43,940 79,592 70,012............................ 2,780 (d) 6 4(b) (e) 263,079,000 444,214,000 454,199,00019(a) [ ][] I-53

29 (a) (b) (c) (d) 43,974,000 256,203,000 190,942,000 1(b) I-54

30 1,000 31............... 1.................................... 1638......................................... 9...................................... 15.......................... 9 9 39 9 39 15 15 1811 13 I-55

C (i) 50,000,000 5,000,000,000 Kingshill Development LimitedKingshillQueenshill Development LimitedQueenshill Longjin Investments LimitedLongjin51%37% 12% (ii) JPG (BVI)200,200,000 (iii) JPG (BVI) KingshillQueenshill Longjin JPG (BVI) 51%37% 12% 667,410,000 484,198,000 157,038,000 KingshillQueenshill Longjin (iv) Po Chai Herbal Technology LimitedPCHT7.6% PCHT 55.2%PCHT7.6% PCHT3,754,000 D [ ] I-56

A. 4.29 [ ] [ ] [ ] [ ] [ ] 1 2 3 [ ] [[ ] ]............ 673,509 [ ] [] [] [ ] [[ ] ]............ 673,509 [ ] [] [] 1. (i) 424,093,000 (ii)21,339,000 1,076,263,000 2. [ ][ ][ ][ [ ]][ ][ [ ]] [ ][ ][6.9 ] [ ][ ] [ [ ]] [ ] 3. [ ] 4. JPG (BVI)200,200,000 5. 7 7 321.8 II-1

[ ] II-2

[ ] II-3

[ ] II-4

1 16 III-1

Thomas Tam Joanna Cheung 388 1 23 2313-2318 MSc, MHKIS [ ] 28 III-2

7 1 D 7 4 97,4149,050.02 3,418,000 3,418,000 (5) 37,1773,453.80 3% (1) (2) (3) (A) (B) (A) (I) (II) (80%) 1/tt t 1,939,669 193,966.90 III-3

(5%) (B) (4) S/TP/26 (5) (3) III-4

22 1. (a) 27(2) (b) 2. (a) (i) IV-1

(ii) (iii) (iv) (v) (vi) IV-2

(aa) (bb) (cc) (dd) (ee) (vii) IV-3

(viii) IV-4

(aa) (bb) (cc) (6) (dd) (ee) (ff) (ix) (x) IV-5

(xi) (60) (b) (c) (i) (ii) (iii) (iv) (v) (d) IV-6

(e) 2(i) (15) (f) IV-7

(g) (15) (18) (h) (21) IV-8

(i) (21)(20) (14) (10) (i) (ii) (95%) (aa) (bb) (cc) (dd) (ee) (ff) (20%) (gg) (j) IV-9

(30) (k) (l) (m) IV-10

(i) (ii) (a) (b) IV-11

(n) (o) (20%) (14) (20%) (p) IV-12

(2)2.50 1.00 (q) (r) 3(f) (s) (i) (ii) IV-13

(t) (i) 12 (ii)12 (iii) (3) (u) 3. (a) (b) (a)(b) (c)37(d) IV-14

(e) (c) (d) IV-15

(e) 34 34 2(m) (f) (a)(b) (c) (a)(b) IV-16

(k) (l) (m) (n) IV-18

(28) (21) (o) (75%) (p) (4) (90%) (4) (2) (1) IV-19

(q) 4. Conyers Dill & Pearman IV-20

A. 1. 388 1 1 23 2313-18 16 2. [] 50,000,000 5,000,000,0000.01 1 Kingshill(i) 50,999 51% Kingshill(ii) 37,000 37% Queenshill(iii) 12,000 12% Longjin KingshillQueenshill Longjin JPG (BVI) 51%37% 12% 667,410,000 484,198,000 157,038,000 KingshillQueenshill Longjin PCHT PCHT464 PCHT7.6% 3,754,000 [ ] [ ] [ ] [ ] [ ] 3. [ ] V-1

4. Citi-Ascent LimitedCiti-Ascent Citi-AscentCiti-Ascent Citi-AscentKoman Services Limited Majestic Path Limited10,000 Jacobson Group Treasury LimitedJacobson Group Treasury Jacobson Group Treasury Jacobson Group Treasury JPG (BVI)10,000 Po Chai Herbal Technology LimitedPCHT PCHT Herbal Sciences Limited PCHT PCHT464 PCHT7.6%3,754,000 Golden Jade Finance Limited10,000 Janson Holdings Limited10,000 10,000 5. (i) [ ] (ii) [ ] a. [ ] [ ] [ ] b. V-2

(iii) a. [ ] [ ] 20% b. (iv) (iv) [ ] [ ] 10% (v) [ ] 6. (a) [ ] [ ] (i) [ ] V-3

[ ] [ ] [ ] 10% (ii) (iii) [ ] 10% 30 [ ] [ ] [ ] 5% (iv) (v) [ ] [ ] (i) [ ] [ ] (ii) [ ] [] V-4

(vi) [ ] 30 (vii) [ ] (b) (c) [ ] [ ] [ ] [ ] (1) (2)(3) (d) [ ] V-5

26 [ ] 25% [ ] [ ] B. 1. (a) (b) Kingshill Development LimitedQueenshill Development LimitedLangjin Investments Limited (c) Bio System Technology LimitedPCHT Herbal Sciences Limited (d) (e) [] 2. (a) 1...... 1146702 5 2...... 1136717 5 3...... N/10831 5 4...... 1995B10099 5 V-6

本文件為草擬本所載資料並不完整且或會作出更改須與本文件封面警告一節一併細閱附錄五編號法定及一般資料商標註冊編號註冊所有人名稱類別註冊地註冊日期屆滿日期 5...... 1122315 Quinwood Limited 5 中國一九九七年十月二十八日二零一七年十月二十七日 6...... 352767 Quinwood Limited 5 中國一九八九年六月三十日二零一九年六月二十九日 7...... 1118211 Quinwood Limited 5 中國一九九七年十月十四日二零一七年十月十三日 8...... 4368304 Quinwood Limited 5 中國二零零八年二月十四日二零一八年二月十三日 9...... 4368301 Quinwood Limited 5 中國二零零九年九月二十一日二零一九年九月二十日 10..... 4368282 Quinwood Limited 5 中國二零零九年九月七日二零一九年九月六日 11..... 6574659 Quinwood Limited 5 中國二零一零年四月七日二零二零年四月六日 12..... 6565644 Quinwood Limited 5 中國二零一二年一月七日二零二二年一月六日 13..... 4309872 Quinwood Limited 5 中國二零零七年十一月二十一日二零一七年十一月二十日 14..... 4309870 Quinwood Limited 5 中國二零零七年十一月二十一日二零一七年十一月二十日 15..... 3973356 Quinwood Limited 5 中國二零零七年二月二十一日二零一七年二月二十日 16..... 19390370 Quinwood Limited 5 香港一九三九年九月十五日二零一九年九月十五日 17..... 300063945 Quinwood Limited 5, 30 香港二零零三年八月十五日二零二三年八月十四日 18..... 300063954 Quinwood Limited 5, 30 香港二零零三年八月十五日二零二三年八月十四日 V-7

本文件為草擬本所載資料並不完整且或會作出更改須與本文件封面警告一節一併細閱附錄五編號法定及一般資料商標註冊編號註冊所有人名稱類別註冊地註冊日期屆滿日期 19..... 300128862 Quinwood Limited 5, 30 香港二零零三年十二月十七日二零二三年十二月十六日 20..... 300165456 Quinwood Limited 5, 30 香港二零零四年二月二十五日二零二四年二月二十四日 21..... 300298422 Quinwood Limited 5, 30 香港二零零四年十月八日二零二四年十月七日 22..... 301700658 Quinwood Limited 5, 30 香港二零一零年八月二十七日二零二零年八月二十六日 23..... P/2488 Quinwood Limited 5 澳門一九九一年九月十日二零二二年九月十日 24..... N/63011 Quinwood Limited 5 澳門二零一二年十一月十二日二零一九年十二月十二日 25..... N/63012 Quinwood Limited 5 澳門二零一二年十一月十二日二零一九年十二月十二日 26..... N/63014 Quinwood Limited 5 澳門二零一二年十一月十二日二零一九年十二月十二日 27..... 300690831 雅柏藥業 5 香港二零零六年七月三十一日二零二六年七月三十日 28..... 301038825 雅柏藥業 5 香港二零零八年一月二十四日二零一八年一月二十三日 29..... 4635910 雅柏藥業 5 中國二零零八年九月二十八日二零一八年九月二十七日 30..... 1174343 雅柏藥業 5 中國一九九八年五月十四日二零一八年五月十三日 31..... 2004B01573 歐化藥業 5 香港二零零二年五月三十日二零一九年五月三十日 32..... 200312343 歐化藥業 5 香港二零零二年十一月六日二零一九年十一月六日 33..... 200316565 歐化藥業 5 香港二零零二年十一月二十九日二零一九年十一月二十九日 V-8

本文件為草擬本所載資料並不完整且或會作出更改須與本文件封面警告一節一併細閱附錄五編號法定及一般資料商標註冊編號註冊所有人名稱類別註冊地註冊日期屆滿日期 34..... 300093645 歐化藥業 5 香港二零零三年十月十四日二零二三年十月十三日 35..... 300093654 歐化藥業 5 香港二零零三年十月十四日二零二三年十月十三日 36..... 300093672 歐化藥業 5 香港二零零三年十月十四日二零二三年十月十三日 37..... 300121878 歐化藥業 5 香港二零零三年十二月三日二零二三年十二月二日 38..... 300310814 歐化藥業 5 香港二零零四年十月三十日二零二四年十月二十九日 39..... 300315855 歐化藥業 5 香港二零零四年十一月九日二零二四年十一月八日 40..... 300383085 歐化藥業 5 香港二零零五年三月十日二零二五年三月九日 41..... 300520299 歐化藥業 5 香港二零零五年十月二十九日二零二五年十月二十八日 42..... 302398852 歐化藥業 5, 30 香港二零一二年十月八日二零二二年十月七日 43..... 302398014 歐化藥業 5 香港二零一二年十月五日二零二二年十月四日 44..... 302999882 歐化藥業 5 香港二零一四年五月十九日二零二四年五月十八日 45..... 303051945 歐化藥業 5 香港二零一四年六月三十日二零二四年六月二十九日 46..... N/86348 歐化藥業 5 澳門二零一四年十二月十日二零二一年十二月十日 47..... N/88098 歐化藥業 5 澳門二零一四年十二月二十九日二零二一年十二月二十九日 48..... 904751 歐化藥業 5 中國一九九六年十一月二十八日二零一六年十一月二十七日 49..... 3666145 歐化藥業 5 中國二零零五年十二月十四日二零二五年十二月十三日 V-9

本文件為草擬本所載資料並不完整且或會作出更改須與本文件封面警告一節一併細閱附錄五編號法定及一般資料商標註冊編號註冊所有人名稱類別註冊地註冊日期屆滿日期 50..... 199916432 法健 5 香港一九九八年六月十一日二零二五年六月十一日 51..... 199910594AA 正美 5,35 香港一九九八年六月二十九日二零二五年六月二十九日 52..... 2002B00992 正美 5 香港二零零零年九月二十日二零一七年九月二十日 53..... 300953019 正美 5 香港二零零七年九月十二日二零一七年九月十一日 54..... 301038924 正美 5 香港二零零八年一月二十四日二零一八年一月二十三日 55..... 301038933 正美 5 香港二零零八年一月二十四日二零一八年一月二十三日 56..... 302736793 正美 5 香港二零一三年九月十三日二零二三年九月十二日 57..... 302744398 正美 5 香港二零一三年九月二十四日二零二三年九月二十三日 58..... 302822346 正美 5 香港二零一三年十二月二日二零二三年十二月一日 59..... 302851092 正美 5 香港二零一三年十二月二十七日二零二三年十二月二十六日 60..... 4082334 正美 5 中國二零零七年十月二十一日二零一七年十月二十日 61..... 4082448 正美 5 中國二零零七年十月二十一日二零一七年十月二十日 62..... 4082330 正美 5 中國二零零七年十二月二十一日二零一七年十二月二十日 63..... 4082335 正美 3 中國二零零八年二月七日二零一八年二月六日 V-10

本文件為草擬本所載資料並不完整且或會作出更改須與本文件封面警告一節一併細閱附錄五編號法定及一般資料商標註冊編號註冊所有人名稱類別註冊地註冊日期屆滿日期 64..... 7099802 正美 5 中國二零一零年八月七日二零二零年八月六日 65..... 19880308 萬輝 5 香港一九八六年十二月十一日二零一七年十二月十一日 66..... 19881096 萬輝 5 香港一九八六年十二月九日二零一七年十二月九日 67..... 19893913 萬輝 5 香港一九八八年三月十九日二零一九年三月十九日 68..... 1999B12515 萬輝 5 香港一九九八年五月二十日二零二五年五月二十日 69..... 199912516 萬輝 5 香港一九九八年五月二十日二零二五年五月二十日 70..... 199912517 萬輝貿易 5 香港一九九八年五月二十日二零二五年五月二十日 71..... 1999B15500 萬輝貿易 5 香港一九九八年十二月二十九日二零二五年十二月二十九日 72..... 300071333 萬輝 5 香港二零零三年九月一日二零二三年八月三十一日 73..... 301892269 利奧化學製藥有限公司 5 香港二零一一年四月十八日二零二一年四月十七日 74..... 1760546 利奧化學製藥有限公司 5 中國二零零二年五月七日二零二二年五月六日 75..... 9360439 利奧化學製藥有限公司 5 中國二零一二年五月七日二零二二年五月六日 76..... 200406233 新科 5 香港一九九九年八月二十六日二零一六年八月二十六日 77..... 301038915 新科 5 香港二零零八年一月二十四日二零一八年一月二十三日 V-11

78..... 300119709 5 79..... 300483318 5 80..... 301038834 5 V-12

1... Jacobson Group 303456450 5,30,35,38,39, Management Limited 42,44 2... Jacobson Group 303701510 5,38,44 Management Limited 3... Jacobson Group 303701538 5,38,44 Management Limited (b) 1.... jacobsonpharma.net Jacobson Group Management Limited 2.... jacobsonpharma.com.hk 3.... jacobsonpharma.hk 4.... jacobsonpharma.cn 5.... jacobsonmedical.com.hk 6.... jacobsonpharma.com 7.... pochaipills.com V-13

C. (a) [ ] [ ] [ ] XV XV7 8 352[ ] 10[ ] (2)(3)............... [ ] (1) [ ] []% (1) [ ] (2) The Jacobson Pharma (PTC) Limited Queenshill The Jacobson Pharma (PTC) LimitedQueenshillThe Jacobson Pharma (PTC) Limited[ ] (3) UBS Trustees (BVI) Limited The Kingshill TrustUBS Nominee Limited Trust CoTrust CoKingshillKingshill[] The Kingshill Trust UBS Trustees (BVI) LimitedTrust Co Kingshill Kingshill[ ]Queenshill (b) [ ] XV2 3 10% V-14

(f) 3. D. 10. 4. (a) XV[ ] XV 7 8 352 [ ] (b) XV2 3 10% (c) D. 9. (d) [] D. 9. (e) [ ] D. 9. (i)(ii) V-16

(f) [ ] 5% D. 1. [ ] 17 (a) (b) (b) (i) (ii) (i) (iii) (iv) V-17

12 (i) 0.1% (ii) 5,000,000 [ ] [ ] [ ] [ ] 17 (f) 30 1 (g) (i) (ii) (iii) (h) (x) 10 V-19

(i) (j) (i) [] [ ] (ii) [] [ ] [ ] [ ] [ ] (k) (l) (m) (s)(v) V-20

(s)(v) 12 (n) (s)(v) 12 (o) (p) 10 (q) 15 V-21

(r) (i) (ii) (s) (i) 10 (ii) (m)(n)(o)(p)(q) (r) (iii) (q) (iv) (r) (v) (vi) (l) (vii) V-22

(viii) (ix) (t) (i) (ii)(iii) (iv) (u) (i) (ii) (c) (iii) (v) (w) (i) (ii) []17.03 V-23

(iii) (iv) (v) [ ] (x) (i) (ii) [ ] (ii) (iii) (iv) (v) (vi) [ ] V-24

2. [ ] 17 (a) (b) (b) (i) (ii) (i) (c) The Jacobson Pharma (PTC) Limited V-25

(d) (e) 39,262,000 (i) (ii) (a) (b) (f) 12 0.5% (g) (h) [ ] 10 V-26

(i) (i) [] [ ] (ii) [] [ ] [ ] [ ] [ ] (j) (k) (p)(vi) (p)(vi) 12 (l) (p)(vi) 12 V-27

(m) 10 (n) 15 (o) (i) (ii) V-28

(p) (i) (ii) (iii) (m)(n)(o)(p) (q) (iv) (p) (v) (q) (vi) (vii) (l) (viii) (ix) (x) (a) (b) (q) (i) (ii) (iii) V-29

(r) (i) [ ] 10 (ii) (s) (t) [ ] [ ] 3. B. 1.(d) (a)[ ] (b)[ ] (a)(b) [ ] (c)[ ] [ ] V-30

4. 5. [][][] 3A.07[ ] 6. 43,000 7. [ ] [] 8. (a) 0.1% (b) (c) [ ] V-31

9................................................................................... 1 6 10. 9 11. 44A 44B 12. 13. E. (a) (i) (ii) V-32

(iii) (iv) (v) (b) (c) (i) (ii) (iii) (d) [ ] [ ] (e) [ ] (f) (g) (h) 32L 4 V-33

1. (a) [ ] (b) B. 1. (c) D. 10. 2. 14 1512 (a) (b) (c) (d) (e) (f) [ ] (g) (h) (i) (j) B. 1. D. 10. (k) (l) VI-1