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SINO BIOPHARMACEUTICAL P LIMITED SINO BIOPHARMACEUTICAL P LIMITED 於開曼群島註冊成立之有限公司 (Incorporated I in the Cayman Islands with Limited Liability) 股票編號 1177 (Stock Code: 1177) 2018 中期報告 2018 Interim Report

1 1177 www.sinobiopharm.com FCCA, CPA 166

1 43 SMP Partners (Cayman) Limited Royal Bank House 3rd Floor. 24 Shedden Road, P.O.Box 1586 Grand Cayman KY1-1110 Cayman Islands 183 22 Codan Trust Company (Cayman) Limited Cricket Square Hutchins Drive P.O. Box 2681 Grand Cayman KY1-1111 Cayman Islands 1 41 09 2 39 Conyers Dill & Pearman, Cayman Boundary Hall, 2nd Floor Cricket Square Hutchins Drive P.O. Box 2681 KY1-1111 Cayman Islands 1 C2 308A 1 22 18 1 24 01 2

972,523 30.0% 142,727 41.9% 11.6033.9% 136,567 24.1% 11.1017.2% 14.5% 553,955 2 24 3

130 4

GMP PVC GMP 5

GMP GMP CN20110001 MSCI 50 1 http://www.sinobiopharm.com 6

6.8% (TKI) 3.1 7

10 8 100 EUROLAND IR 100 100 8

10 3 1.1 6 62 14 1.1 13 2 13 2 8 2 482 60 45145 141 972,523 30.0% 142,727136,567 41.9%24.1% 11.60 11.10 33.9%17.2% 553,955 1 12,895,516,937 12.731,013,002,116 33.6% 57.6% 9

333,882 34.3% 4,633 20,648 3.2% 87,744 12,621 173,557 7.2% 21,334 8.4% 6,785 19.4% 10

137,441 14.1% 7,542 39,720 22.9% 32,057 9.7% (DDS) GMP 39,680 20,092 19.2% 104,485 10.7% 11

8,272 22,296 33.2% 10,914 2.1% 10,230 35.2% 8,077 10,81828.1% 7,214 43.2% 95,914 9.9% DDS 89,669 25.1% 30,959 77.2% 81,932 8.4% 55,436 32.8% 14,318 31.1% 12

57,085 5.9% 11,785 5.9% 36,725 122.1% 50,384 5.2% 33,585 12,052 60.5% 42,640 4.4% 25,659 20.2% 10,657 24.1% 32,676 3.4% 23,027 9,060 13

6,405 0.7% 1 5,448 21.6% 65,361 54,014 312,950 264,743 68,600 50,000 42,000 31,200 28,00025,000 21,000 19,00010,250 17,900 8.9% 14

(i) 17,77419,042Karolinska Development AB 272,858,2948%(ii) 32,474 94,373 9,308 2,431 4 937 2482 54 37205 22 26138 132,81813.7% 32 27 2 380 76 2 2 6361967 15

553,955 418,814 107,950 74,131221,380 220,990 38,732 31,600 3,498,560 2,093,534 1,068,884 832,429 30.6% 39.8% 16

19,075 882,506,000 601,134,000 (i) (ii)17,599,000 18,882 17

18

3 9,725,232 7,482,859 (1,858,501) (1,568,413) 7,866,731 5,914,446 3 337,014 223,739 (3,977,362) (3,169,426) (462,991) (254,581) (1,377,667) (1,173,558) (1,328,179) (1,155,532) 4 (51,160) (34,127) 63,105 177,776 5 2,397,670 1,684,269 6 (428,779) (285,637) 1,968,891 1,398,632 1,365,669 1,100,582 603,222 298,050 1,968,891 1,398,632 8 11.10 9.47 11.10 9.47 7 19

1,968,891 1,398,632 73,525 (113,300) 73,525 (113,300) 2,042,416 1,285,332 1,438,428 988,528 603,988 296,804 2,042,416 1,285,332 20

4,862,571 3,483,253 364,275 370,163 1,030,211 789,362 9,908,639 88,926 243,141 219,249 353,112 1,048,155 653,605 540,138 177,735 190,421 456,209 382,574 55,979 42,979 18,105,477 7,155,220 1,201,206 918,819 9 3,243,388 2,051,290 3,441,735 3,030,718 3,129,501 2,647,426 324,739 943,726 10 5,539,552 4,188,140 16,880,121 13,780,119 11 841,482 928,607 184,520 292,595 5,584,051 3,725,942 1,079,501 741,307 7,689,554 5,688,451 9,190,567 8,091,668 27,296,044 15,246,888 21

571,654 241,912 2,213,800 2,209,897 213,834 184,030 2,999,288 2,635,839 24,296,756 12,611,049 12 279,208 170,033 (188,819) 20,203,373 9,038,761 20,293,762 9,208,794 4,002,994 3,402,255 24,296,756 12,611,049 22

170,033 1,128,455 (371,473) 251,091 22,691 1,877,959 (466,887) 6,596,925 9,208,794 3,402,255 12,611,049 1,365,669 1,365,669 603,222 1,968,891 (10) 943 (736) 72,562 72,759 766 73,525 (10) 943 (736) 72,562 1,365,669 1,438,428 603,988 2,042,416 20,257 10,294,506 10,314,763 10,314,763 88,918 (88,918) (188,819) (188,819) (188,819) 958,443 958,443 (961,692) (961,692) (273,945) (273,945) (273,945) (205,459) (205,459) (205,459) 279,208 11,334,043 (371,483) (188,819) 252,034 22,691 1,877,223 (394,325) 7,483,190 20,293,762 4,002,994 24,296,756 170,033 1,128,455 (169,686) 185,993 22,691 1,420,955 (83,207) 5,213,051 95,150 7,983,435 2,758,476 10,741,911 1,100,582 1,100,582 298,050 1,398,632 (112,054) (112,054) (1,246) (113,300) (112,054) 1,100,582 988,528 296,804 1,285,332 698 698 (788,046) (788,046) (95,150) (95,150) (95,150) (232,736) (232,736) (232,736) /( ) 14,022 (14,022) 170,033 1,128,455 (169,686) 185,993 22,691 1,434,977 (195,261) 6,066,875 8,644,077 2,267,932 10,912,009 23

2,058,541 3,218,565 491,836 (1,585,214) (1,338,792) (1,389,331) 1,211,585 244,020 3,692,044 3,498,538 134,643 (154,594) 5,038,272 3,587,964 2,512,106 1,696,909 2,526,166 1,891,055 5,038,272 3,587,964 24

1. (a) (b) (c) 25

1. (i) (ii)(iii)(i) (ii)(iii) 2. (a) (b) (c) (i) (ii) 26

2. : 9,463,701 2,665 258,866 9,725,232 2,411,617 35,350 15,279 2,462,246 56,366 63,105 (184,047) 2,397,670 (428,779) 1,968,891 18,545,122 14,644,792 986,363 34,176,277 353,112 456,209 34,985,598 6,769,302 3,268,991 252,195 10,290,488 398,354 10,688,842 188,928 12,627 9,185 210,740 616,995 125 52,624 669,744 462 26 488 27

2. 7,266,830 1,935 214,094 7,482,859 1,496,927 96,615 37,261 1,630,803 22,302 177,776 (146,612) 1,684,269 (285,637) 1,398,632 13,146,270 4,585,784 611,582 18,343,636 1,017,212 245,522 19,606,370 5,560,958 2,712,396 299,031 8,572,385 121,976 8,694,361 144,116 15,125 9,200 168,441 436,967 69 437,036 527 37 564 28

2. (a) 90% (b) 10,805,779 1,658,707 7,272,614 4,690,300 27,084 25,908 18,105,477 6,374,915 10% 29

3. 9,498,702 7,297,582 226,530 185,277 9,725,232 7,482,859 56,366 22,302 8,398 8,364 8,650 6,207 14,873 14,714 1,682 2,579 117,132 59,359 2,468 2,686 33,207 13,612 242,776 129,823 1,163 976 93,075 67,721 25,219 94,238 93,916 337,014 223,739 30

4. 51,160 34,127 5. 1,858,501 1,568,413 190,715 150,863 10,574 11,509 702 482 8,749 5,587 1,328,179 1,155,532 (1,163) (976) 488 564 (56,366) (22,302) (8,650) (6,207) (117,132) (59,359) 24,308 (25,219) 978 2,445 1,921 712,183 488,427 170,323 112,707 882,506 601,134 24,692 16,288 37,289 (70,165) 31

6. 424,738 299,058 4,041 (13,421) 428,779 285,637 2011 6 16.5%16.5% 15% 25% 10% 5% 32

7. 2 2 18322 8. (a) 1,365,669 1,100,582 12,305,376 11,624,789 11.10 9.47 33

8. (b) 1,365,669 1,100,582 12,305,376 11,624,789 2,210 12,307,586 11,624,789 11.10 9.47 9. 60180 90 3,011,379 1,654,569 91180 186,201 361,657 180 45,808 35,064 3,243,388 2,051,290 34

10. 2,512,106 1,135,025 2,526,166 2,557,019 501,280 496,096 5,539,552 4,188,140 11. 90 597,697 704,689 91180 149,304 189,163 180 94,481 34,755 841,482 928,607 12. 12,637,791,4870.025 7,412,192,2090.025 279,208 170,033 35

13. a 878 531 a 3,275 1,800 b 1,557 1,557 (a) (b) 36

571 XV78 352 (1) 1,519,503,174 1,519,503,174 12.02% (2) 210,600,000 1,623,190,083 1,833,790,083 14.51% (3) 95,056,500 2,700,000,000 2,795,056,500 22.12% 98,598,000 98,598,000 0.78% (1) 11,519,503,174 91.33% (1) Validated Profits Limited1,623,190,083 (2) Remarkable Industries Limited 1,575,000,0001,125,000,000 37

229,250 0.18% 26,583 0.53% XV XV78 352 38

XV 23 336 Validated Profits Limited (1) 1,623,190,083 12.84% (2) 1,575,000,000 12.46% 1 (3) 1,519,503,174 12.02% Remarkable Industries Limited (2) 1,125,000,000 8.90% (1) Validated Profits Limited (2) Remarkable Industries Limited (3) 1 91.33% XV23 336 39

494,146,147 10% 1% (i) 0.1% (ii)5 301 40

(i) (ii) (iii) 222,365,766 3%10 41

1,000 A.6.7 42

3.10 3.10(A) 13.18 300,000,000 43

44