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170 170~182 年 CHIA-NAN ANNUAL BULLETIN VOL. 32, PP. 170 182, 2006 精盧理理摘要理行來行 (1) ph (2) 行 ph (3) (4) ph 6.01-8.06 ph 6.00-6.50 刺理前言理不不來不良理良理理度類料 (1) (Tela subcutanea) (Corium; Dermis) 淋 (Epidermis) (stratum germnativum) 更 (stratum) 狀 (stratum spinosum) 見粒 ( 粒 stratum granulosum) 不 ( stratum lucidum) 落 ( stratum corneum) 不例度不異例率

盧 171 例來說數來見類例 (Pili supraorbiltales) (Pili infrarbitales) (Pili angulares oris) (root sheaths) 說 (bulb of hair) 裡不狀列鱗狀 (scalelike folds) 度數量異落來不復度落 (2) 理六 (3,4) 理刺 1. 理了若不良 2. 泌量離類 3. 不利 4. 刺刺力不冷滑更狀理刺刺度力力

172 流量量狀度量度不度冷量泌泌泌裂泌不泌泌力流 1. 離 2. 量 3. 量量度度度理不不 1. 不不不 2. 3. 4. 林蠟不類 A D E 易 5. 量了了來了更利六

盧 173 裂泌列參理了理理不不不度來說不行不濫數列 1. 泌不 2. 滑烈輻裂 3. 力老 4. 力異 5. 實驗材料與方法 ph ph 量度 ph(ph Measurement on the Skin Surface) 異 ph 年類不異 1. 來 ph 度利 (Acid-Base) 例來 ph (Colorimetric ph) (5) 不便不 ph 2. Skin-pH-Mate ph900 度量度 ph 量來說參數不度參

174 離 (H + ) H + 度 ph 度度行 ph=4 ph=7 行留 3 3 ph 參 1. 力 2. 3. 度 4. ph 6.0-6.5 刺 5. 理理良滑易理 6. 流 1 1 : 理數行量數 81 數 7 量量易量流理 (Fick) 律利理量兩度度狀流料流料 7 量流 ( TEWL) 量行

盧 175 離 3.6N 力 1 料流流量 2 錄流流數來流度度度度行連連流度度 7 3.5 更錄料六 (6) 類刺來刺量 (Finn chamber) 若流濾 15-30 若類類 (6) 1 刺類 + 不刺 ++ +++ 烈 ++++ 烈 IR NT 刺結果與討論 ph 不不度來說不行不濫數 2 ph 6.01-8.06 ph 行 ph ph 流

176 测度力 2 ph ph 5 in 1 亮 7.78 5 in 1 7.00 5 in 1 6.01 8.00 8.06 7.21 7.85 2 in 1 6.30 3 ph 留 ph 6.25 殺力不易刺力降狀粒 (2) ph 6.5 易 ph ph 5.0-6.5 力力度來力復狀 ph 老力復狀理狀理力 ph 量 ph ph 理 3 ph 量 1 2 6.03 6.06 6.05 6.05 6.47 6.48 6.48 6.33 6.43 6.38 6.50 6.64 6.64 6.64 來 7.0 ph 6.5 理理 ph 6.5 理 ph 1912 年

盧 177 丹 (7) 離度來度數 ph 來 ph 離 (H + ) 度離 (OH - ) 度例來兩度數 ph 7.0 不不不不論理理理理理不泌若不若刺力降殺力降力不了老易裂度 ph 度度量參數狀 phph 6.0-6.5 不度 (ph <6.0) 不 ( ph >6.5) 若度不 ( ) 泌不 1. 料量離 20 兩 6 離 4 理 4 離 0.05 0.5 度量 3 量 ph 量 1 0.2 H 2 O 量 100.0g

178 2. 料量離 20 兩 6 理 3 2 離 0.05 0.5 度量 2 2 ph 量 1 0.2 H 2 O 量 100.0g 1 流冷不 70 料狀度降 45 料 ph 度度行度不 ( 不 75 ) (3,8,9) 1. 度狀 2. 理 JR-400 料量料 15 若更 3. 量度冷度冷 70 冷度瑩若 4. 料料刺量度易度 ( 45 量 0.4 0.8 5. 更不量更更度不 6. 度數度度理度量量

盧 179 度度量不 1 類刺度類量度降 7.pH ph 降 45 ph 8. 量量不量量刺復來更亮麗亂狀 ph 理不刺理更利靈不論不 Silicon Silicon 易塞兩理不刺易不留刺理不度不别易易禮量量 4 流 60 復來 10 20 量不 10 狀裂量刺 5 刺不論刺刺

180 不行理 4 量流量量 20.8 17.4 15 8.8 10.4 30 13.7 12.2 60 21.1 21.3 90 22.6 21.9 120 21.7 20 度度 28.5 55 5 0 15 狀

盧 181 30 狀結論異 ph ph 理不刺易不留刺禮力利靈參考文獻 1. 李理臨 1998 2. 金 1990 3. 梁 2002 4. 2001 5. G.Mattock and D.M.Band, Interpretation of ph and cation measurements. In: Glass Electrodes for Hydrogen and Other Cations, G. Eisemnan, Ed. Derkker, New York, p.45,1967. 6. 立 7. 識 119 陵 1993 8. / 1999 9. Knowlton J,et al., Handbook of Cosmetic Science and Technology. New York: Elsevier Advanced Technology, Oxiford, 397-434, 1993.

182 CHIA-NAN ANNUAL BULLETIN VOL. 32, PP. 170 182, 2006 ABSTRACT Development of a New Formula for Pet Dog Shampoo Ching-Shan Hsu and Ming-Chun Lu Department of Environmental Resources Management, Chia-Nan University of Pharmacy and Science, Tainan, Taiwan 71710, R.O.C. ABSTRACT This study was to explore a new shampoo for pet dog according to the isoelectric physiology of pet dog hair and skin. There were four stages for completing this work: (1) measuring the ph of some commercial dog shampoos, (2) detecting ph on the dog skin, (3) developing some new formulas of dog shampoo and (4) investigating the safety of new dog shampoo. Results show that the phs of the commercial dog shampoos are between 6.01-8.06. However, the ph on the dog skin is in the range of 6.00-6.50. The new dog shampoo developed in this study has a similar ph range with dog skin. In addition, the evaluation of the new shampoo for the irradiation on dog skin is negative. Therefore, this new shampoo can be applied for commercial purpose. Key words: Pet dog, Shampoo, Isoelectric physiology