SIHUAN PHARMACEUTICAL HOLDINGS GROUP LTD. 0460 2410 1
1,278,306 1,440,310-11.2% 1,305,499-2.1% 1,025,743 1,018,367 0.7% 968,486 5.9% 944,490 968,220-2.5% 720,036 31.2% 765,671 842,456-9.1% 606,479 26.2% 765,671 716,685 6.8% 606,479 26.2% 80.2% 70.7% 74.2% 61.5% 58.4% 48.9% 8.08 8.87 6.40 60 74 73 182 92 122 0.4 1.8 2.1% 70.7% 80.2% 58.4% 61.5% 6.8% 765.7 26.2% 182 92 11.3% 1,004.3 0.4 1.8 2
4 2,905,383 2,453,594 4 17,794 17,814 4 2,843,903 2,843,903 4 1,293,696 1,338,006 4 821,740 702,661 7 1,126,436 1,012,091 5 195,376 127,514 16 268,083 220,000 16 39,076 15,389 62,880 9,487,800 8,817,539 282,012 227,970 6 673,142 747,141 16 2,791,257 2,967,354 1,457,181 831,859 5,203,592 4,774,324 14,691,392 13,591,863 3
8 78,233 78,233 8 4,093,317 4,093,317 143,709 166,210 7,384,643 6,719,232 11,699,902 11,056,992 299,446 279,078 11,999,348 11,336,070 5 250,878 264,396 17 16,248 11 62,341 88,084 83,145 412,612 352,480 10 1,753,308 1,804,787 17 362,173 29,401 70,829 127,761 11 6,789 27,697 2,279,432 1,903,313 2,692,044 2,225,793 14,691,392 13,591,863 4
12 1,278,306 1,440,310 (252,563) (421,943) 1,025,743 1,018,367 12 97,340 66,470 12 304,108 134,543 125,771 (100,971) (71,025) (359,803) (269,004) (21,927) (36,902) 944,490 968,220 (2,039) (21,405) 28,966 921,046 997,186 13 (134,817) (156,716) 786,229 840,470 765,671 842,456 20,558 (1,986) 786,229 840,470 14 8.08 8.87 5
786,229 840,470 36,352 (33,920) 2,432 786,229 842,902 765,671 844,888 20,558 (1,986) 786,229 842,902 6
79,443 (255) 4,344,229 137,096 6,340,925 10,901,438 69,655 10,971,093 842,456 842,456 (1,986) 840,470 2,432 2,432 2,432 2,432 842,456 844,888 (1,986) 842,902 9(ii) 889 889 889 (955) (250,912) (251,867) (251,867) (1,210) 1,210 (359,901) (359,901) (359,901) (520,910) (520,910) (520,910) 346 346 78,233 4,093,317 140,417 6,302,570 10,614,537 68,015 10,682,552 7
78,233 4,093,317 166,210 6,719,232 11,056,992 279,078 11,336,070 9 (22,864) 22,864 78,233 4,093,317 143,346 6,742,096 11,056,992 279,078 11,336,070 765,671 765,671 20,558 786,229 765,671 765,671 20,558 786,229 9(ii) 173 173 173 15 (123,124) (123,124) (123,124) 190 190 (190) 78,233 4,093,317 143,709 7,384,643 11,699,902 299,446 11,999,348 8
1,261,941 1,076,744 (257,625) (174,032) 1,004,316 902,712 (135,750) (19,999) 49,646 (419,475) (799,995) (109,115) (195,294) (4,286) (14,467) (69,264) (11,659,558) (4,131,600) 11,845,490 3,629,000 131 65,182 33,920 (486,776) (1,448,658) 9
210,906 (251,867) 20,000 (123,124) 107,782 (251,867) 625,322 (797,813) 831,859 2,407,073 1,457,181 1,609,260 10
1. Clarendon House, 2 Church Street, P.O. Box HM 1022, Hamilton HM DX, Bermuda 1 4905 2. 2.1 34 2.2 11
2 4 9 15 15 40 22 4 9 15 1 28 15 15 11 18 15 15 15 9 9 39 9 12
(a) 9 9 SPPI SPPI SPPI 39 39 9 39 9 39 13
(b) 9 39 9 9 12 12 12 90 9 3. 10% 90% 14
4. 2,453,594 17,814 1,338,006 2,843,903 702,661 545,783 4,177 127,828 (1,414) (518) 518 (92,062) (538) (48,487) (8,749) 2,905,383 17,794 1,293,696 2,843,903 821,740 2,104,299 29,103 578,998 2,247,728 647,769 211,999 9,052 48,332 733,130 492,933 61,623 (57) (80,060) (20,792) (81,729) (889) (64,390) (7,831) 2,202,784 28,214 1,256,790 2,719,869 701,561 15
796,496,100 913,495,000 444,713,711 402,360,000 5. 1 127,514 35,883 67,862 78,297 195,376 114,180 2 264,396 74,094 182,186 (13,518) (4,405) 250,878 251,875 16
6. 187,256 167,854 201,209 290,589 115,387 102,341 (i) 109,651 107,959 9,672 9,675 49,967 68,723 673,142 747,141 (i) (a) 30,000 30,000 (b)) 79,651 77,942 Medifood International SA 17 109,651 107,959 (a) 30,000,000 10% 5% (b) 69,400,000 10,251,000 4.75% 17
3 176,325 161,537 3 6 6,947 2,613 6 1 3,980 3,700 1 4 4 187,256 167,854 7. 636,144 551,557 490,292 460,534 1,126,436 1,012,091 18
8. 0.01 9,586,684 79,443 (255) 4,344,229 4,423,417 (i) (115,602) (1,210) 255 (250,912) (251,867) 0.01 9,471,082 78,233 4,093,317 4,171,550 0.01 9,471,082 78,233 4,093,317 4,171,550 0.01 9,471,082 78,233 4,093,317 4,171,550 (i) 282,283,000 251,867,000 115,602,000 19
9. (i) Plenty Gold Enterprise Limited Plenty Gold MSPEA Pharma Holdings B.V. Plenty Gold 33,750,000 MSPEA Pharma Holdings B.V. 3,750,000 3.19 14,150 3.19 19,750 0.70 2,050 35,950 31,448,172 234 1.57 20
(ii) 1.57 2,904 5,403 1.57 (990) (1,545) 1.57 (18) (239) 1.896 3,619 1.57 1,896 2,904 1,896,000 2,904,000 173,000 889,000 21
10. (i) 34,586 34,320 (ii) 360,594 56,860 57,635 300,000 300,000 (iii) 83 83 228,120 230,796 989,463 505,833 53,390 180,749 40,638 52,891 1,920 48,248 81,886 1,753,308 1,804,787 (i) 40 (ii) 15 (iii) 6 31,170 24,329 6 12 885 3,766 1 2,531 6,225 34,586 34,320 22
11. (i) 44,222 (ii) 69,130 71,559 69,130 115,781 (i) 21,300 (ii) 6,789 6,397 6,789 27,697 62,341 88,084 (i) 15 (ii) 23
12. (i) 1,278,306 1,438,304 2,006 1,278,306 1,440,310 10,037 20,317 1,541 1,627 13,923 71,839 44,526 97,340 66,470 (ii) 289,940 129,935 10,592 3,576 4,608 304,108 134,543 (i) (ii) 24
13. 216,197 239,418 (81,380) (82,702) 134,817 156,716 (i) (ii) (iii) 25% 15% 25
14. (a) 765,671 842,456 9,471,082 9,494,407 8.08 8.87 (b) 15. 1.3 123,124 0.4 1.8 37,884 170,479 26
1.8 1.3 123,124,000 0.4 1.8 16. (i)) 128,250 120,000 (ii)) 100,000 100,000 (iii)) 39,833 39,076 268,083 259,076 (iv)) 2,791,257 2,967,354 2,791,257 2,967,354 2,831,090 3,006,430 27
(i) 120,000,000 120,000,000 10% 5% (ii) 100% 3% (iii) KBP Biosciences Holding Limited Lindeman Asia No.12 Investment Fund (iv) 4.82% 4.5% 17. 10(ii)) 345,036 11(i)) 33,385 378,421 345,036 17,137 362,173 16,248 28
A. 1,278.3 11.2% 2.1% 765.7 9.1% 26.2% 8.62% 1.44% II 29
26.4% 80.8% 46.1% 2018 2018 1. 30
2. 31.6 3. 4. 31
282.7 26.4% 17.7% 4,209 21 28 2017 2018 277.7 29.2% 5.7% 4,145 24 26 158.2 32
80.8% 22.5% 4,326 21 25 151.3 29.2% 14.2% 3,859 30 25.3 27.4% 45.0% 280 9 23 33
H2 160 26.2 51.6% 45.8% 260 10 25 17.1 74.1% 79.6% 274 11 25 16.9% 1,182.2 92.5% 34
223,634 282,686 26.4% 392,507 277,707-29.2% 87,478 158,172 80.8% 213,703 151,312-29.2% 112,858 79,771-29.3% B(II) 69,452 75,765 9.1% GM1 79,549 67,508-15.1% 19,844 25,278 27.4% 45,135 16,391-63.7% 2,195 14,314 552.2% 35
16.0% 96.1 7.5% 17,286 26,211 51.6% 9,794 17,053 74.1% 12,289 8,900-27.6% 10,237 8,859-13.5% 11,399 9 I II (EGFR) 36
1 2 3 4 5 6 7 8 9 10 600 PCT 40 1 4 2 170 65 37
3 18 71 48 7 71 38
B. C. 1,440.3 11.2% 1,278.3 162.0 1,182.2 175.2 92.5% 82.9 16.0% 96.1 7.5% 252.6 19.8% 39
1,025.7 1,018.4 7.3 70.7% 80.2% 134.5 169.6 304.1 29.9 101.0 269.0 33.8% 359.8 91.9 48.8% 136.8 36.9 21.9 997.2 7.6% 921.0 40
156.7 14.0% 134.8 840.5 6.5% 786.2 842.5 9.1% 765.7 125.8 6.8% 2.0 20.6 1,457.2 831.9 2,791.3 2,967.4 41
2,757.8 2,757.8 33.5 2,791.3 2,213.8 2% 1,457,181 831,859 210,906 1,246,275 831,859 42
673.1 747.1 74.0 282.0 228.0 182 92 2,905.4 451.8 18.4% 2,843.9 2,843.9 43
1,293.7 1,338.0 1,753.3 51.5 15 215.5 44
151.5 127.8 45
182.7 109.1 69.3 4.3 21.9 18.1 3.8 448,516 448,516 3,707 220.8 155.9 46
47
2410 0.4 0.5 1.8 48
183 22 (http://www. hkexnews.hk) http://www.sihuanpharm.com) (http://www. sihuanpharm.com) http://www.hkexnews.hk) 183 22 sihuanpharm-ecom@hk.tricorglobal.com 49