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1 義大醫院第六版處方集增修版 ( 第一次公告 ) 公告日期 : 102/12/ p.150 原處方集內容 Klean-Prep C 6 Unknown 4 Klean-Prep 68.6g/sachet <KKLEAN> Each sachet contains: Polyethylene glycol g Sodium sulfate anhydrous g Sodium bicarbonate g Sodium chloride g Potassium chloride g Aspartame g Bowel preparation before colonoscopy, colonic surgery, radiological examination and other related procedures 第十八次藥政會決議新藥, 並刪除 Klean-Prep p.73 Docetaxel D 4 Unknown 1 Tyxan 20mg/ <CDOCET1> Tyxan 80mg/2ml/vial <CDOCET2> Breast cancer, non-small cell lung cancer, gastric cancer, head- neck cancer, prostate cancer 廠商告知藥品規格及外觀變更 p.163 Rivaroxaban C 4 Unsafe 1 Xarelto 10mg/FC. tab <KRIVARO> Postoperative thromboprophylaxis in patients who have undergone hip or knee replacement surgery Arthroplasty of knee Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 2 weeks Repair of hip Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 5 weeks ALT and AST increase, anemia, nausea, bleeding 1. 服用本品須監測出血徵狀 2. 本品含乳糖, 患有罕見遺傳疾病, 包含乳糖不耐症乳糖酶缺乏症或葡萄糖 - 半乳糖吸收不良者不應服用本藥修正後處方集內容 GI Klean powder C 6 Unknown 4 GI Klean powder 68.6g/sachet <KKLEAN1> Each sachet contains: Polyethylene glycol g Sodium sulfate anhydrous g Sodium bicarbonate g Sodium chloride g Potassium chloride g Aspartame g Bowel preparation before colonoscopy, colonic surgery, radiological examination and other related procedures Docetaxel D 4 Unknown 1 Tynen 20mg/1ml/vial <CDOCET1> Tynen 80mg/4ml/vial<CDOCET2> Breast cancer, non-small cell lung cancer, gastric cancer, head- neck cancer, prostate cancer Rivaroxaban C 4 Unsafe 1 Xarelto 10mg/FC. tab <KRIVARO> Xarelto 15mg/FC. tab <KRIVAR2> Xarelto 20mg/FC. tab <KRIVAR1> 10mg: Postoperative thromboprophylaxis in patients who have undergone hip or knee replacement surgery 15 and 20mg: nonvalvular atrial fibrillation and treatment of deep vein thrombosis and pulmonary embolism Arthroplasty of knee Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 2 weeks Repair of hip Prophylaxis PO 10mg qd beginning at least 6 to 10 hours after surgery and continued for 5 weeks Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation PO 15~20mg qn; max: 20mg/day Treatment of deep vein thrombosis and prevention of recurrent DVT and pulmonary embolism PO 15mg bid for 21days (max: 30mg/day) then 20mg qd (max: 20mg/day) ALT and AST increase, anemia, nausea, bleeding 1. 服用本品須監測出血徵狀 2. 本品含乳糖, 患有罕見遺傳疾病, 包含乳糖不耐症乳糖酶缺乏症或葡萄糖 - 半乳糖吸收

2 第十八次藥政會決議新藥 p.148 Metoclopramide B 1 Safe 4 Primperan 10mg/2ml/amp <CMETOCL> Promeran 3.84mg /tab <KMETOC1> Aswell syrup 60mg/60ml/bot <KMETOC3> 學名藥比價, 更換廠商 p.143 Famotidine B 4 Safe 1 Fadin Lyo-injection 20mg/vial <CFAMOTI> Quimadine 20mg/tab <KFAMOTI> 廠商來函告知藥品商品名變更 p.109 Irbesartan D 4 Unknown 1 Aprovel 150mg/tab <KIRBESA> Hypertension Children 6-12 yrs: PO initial 75mg qd; max: 150mg/day Adults: PO initial 150mg qd; max: 300mg/day Diarrhea, dyspepsia, upper respiratory infection, headache, fatigue 第十二次藥政會決議新藥, 並刪除 Irbesartan 150mg/tab p.213 Sulfinpyrazone Unknown 1 Sulfin 100mg/tab <KSULFIN> Gout and gouty arthritis PO mg/day; max: 800mg/day Stomach pains, nausea, vomiting, exacerbation of ulcers, mild granulocytopenia 1.Patients with a history of healed peptic ulcer 2. 需依腎功能調整劑量 Acute attack of gout, blood dyscrasias 第十七次藥政會決議新藥, 並刪除 Sulfinpyrazone 不良者不應服用本藥 3. 外科手術與介入治療 : 應於該治療的至少 24 小時前停用 Xarelto 4. 硬腦膜外導管應在服用本品最後一劑後的 18 小時之後再移除, 導管取出後的 6 個小時之後才可再服用本品, 如發生外傷性穿刺, 則給藥時間應延後 24 小時 Metoclopramide B 1 Safe 4 Promeran 9.08mg/ 2ml/amp <CMETOCL> Promeran 3.84mg /tab <KMETOC1> Aswell syrup 60mg/60ml/bot <KMETOC3> Famotidine B 4 Safe 1 Fadin Lyo-injection 20mg/vial <CFAMOTI> Famotidine 20mg/tab <KFAMOTI> Irbesartan D 4 Unknown 1 Aprovel 150mg/tab <KIRBESA> Aprovel 300mg/tab <KIRBES1> Hypertension, diabetic nephropathy Hypertension Adults: PO initial 150mg qd; max: 300mg/day Diabetic nephropathy Adult: PO initial 150mg qd, target maintenance does 300mg qd Diarrhea, dyspepsia, upper respiratory infection, headache, fatigue Febuxostat C 4 Unknown 1 Feburic 80mg/tab <KFEBUXO> Chronic management of hyperuricemia in patients with gout PO initial 40mg qd, increased to 80mg qd if sua 6mg/dl after 2 weeks Liver enzymes abnormal, rash, nausea, arthralgia, gout attack(during initial treatment) 開始使用後, 由於血清尿酸濃度改變導致尿酸鹽從組織沉積移轉, 痛風可能會發作, 故建議併用 NSAIDs 或 Colchicine 以預防痛風發作, 預防性治療效益達 6 個月 ; 治療過程若痛風發作無需停用 Feburic 正在使用 Azathioprine 或 Mercaptopurine 的患者無症狀高尿酸血症禁用

3 p.151 Lactulose B 4 Unknown 1 Lactul 500ml/bot, 1ml: Lactulose 666mg <KLACTUL> 學名藥比價, 更換規格 p.28, 30 Drug name Combivir Lamivuding 150mg+Zidovudine 1 tab bid 300mg/tab < KCOMBI> 60kg 400mg qd Didanosine (DDI) <60kg 250mg qd Kivexa Lamivudine (3-TC) Stavudine (d4t) Videx EC 250mg/cap <KDIDANO> Videx EC 400mg/cap <KDIDAN2 > Abacavir 600mg+Lamivudine 300mg/tab<KKIVEXA> 3-TC 150mg/tab <KLAMIV2 > Zerit 30mg/cap <KSTAVU1> Zerit 40mg/cap <KSTAVU2> > 40 kg, 1 tab qd 3mon-16yrs:4mg/kg bid Adults: 150mg bid 60kg: 40mg q12h; <60kg: 30mg q12h Lactulose B 4 Unknown 1 Lactul 300ml/bot, 1ml: Lactulose 666mg <KLACTUL> Drug name Kaletra Lopinavir 200mg+Ritonavir 2 tab bid 50mg/ tab <KKALET1> Atazanavir Darunavir Ritonavir Reyataz 200mg/cap <KATAZAN> Reyataz 150mg/cap <KATAZA1> Prezista 600mg/tab <KDARUNA> Prezista 400mg/tab <KDARUN1> 第十一次藥政會決議新藥 Atazanavir 150mg/cap, 並刪除 Stavudine 40mg/cap p.286 Bethanechol C 4 Unknown 1 Mesacol 25mg/tab <KBETHAN> Neurogenic bladder atony with retention, postoperative nonobstructive urinary retention Urinary retention PO mg/day tid-qid AC, max: 50 mg Abdominal cramps, diarrhea, excessive lacrimation, miosis, flushing of skin 處方集內文勘誤 p p.16, 122 Selegiline C 4 Unknown 1 Seginine 5mg/tab <KSELEGI> 學名藥比價, 更換廠商 Gentamicin C 6 Unknown 1 Gentamycin 80mg/2ml/vial<CGENTA2> 參閱 p.16 Garamycin cream 0.1%, 15g/tube <WGARAMY> Oftalmolosa oint 0.3%, 5g/tube<WGENTA3> 參閱 p.253 Norvir 100mg/soft gelatin cap <KRITONA > For treatment-naïve and therapy-experienced patients Reyataz 300mg + Ritonavir 100mg qd For treatment-naïve patients who are unable tolerate Ritonavir Reyataz 400mg qd mg bid concomitantly with ritonavir 100mg Adult: initial 300mg bid, then increase by 100 mg bid every 2 to 3 days, max 600mg bid 2yrs Children: initial, 250 mg/m(2) bid, then increase by 50 mg/m(2) bid every 2 to 3 days, maintenance dose of 350 to 400 mg/m(2); max: 600mg bid Bethanechol C 4 Unknown 1 Mesacol 25mg/tab <KBETHAN> Neurogenic bladder atony with retention, postoperative nonobstructive urinary retention Urinary retention PO mg/day tid-qid AC, max: 50 mg Abdominal cramps, diarrhea, excessive lacrimation, miosis, flushing of skin Selegiline C 4 Unknown 1 Parkryl 5mg/tab < KSELEGI> Gentamicin C 6 Unknown 1 Gentamycin 80mg/2ml/vial<CGENTA2> 參閱 p.16 Gentamycin cream 0.1%, 15g/tube <WGARAMY> Oftalmolosa oint 0.3%, 5g/tube<WGENTA3> 參閱 p.253

4 p p.203 Gentamicin oph sol'n 0.3%,5ml/bot<WGENTA2> 參閱 p.253 Gentamicin oph sol'n 0.3%,5ml/bot<WGENTA2> 參閱 p.253 原廠商供貨不穩, 更換廠商第十三次藥政會決議新藥 Glipizide C 4 Unknown 1 Glidiab 5mg/tab <KGLIPIZ> Oxybutynin B 4 Unknown 4 Oxbu 5mg/ER tab < KOXYBU1> Smptoms associated with overactive uninhibited neurogenic or reflex neurogenic bladder (eg, urgency, frequency, leakage, urge incontinence, dysuria) PO initial 5mg qd, dose may be increased weekly in 5mg increments; max: 30mg/day Xerostomia, constipation, headache, dizziness, somnolence Precausions 1. 需整粒吞服, 不能咀嚼分開或壓碎 2. 藥物含在一個無吸收性的外殼內, 外殼會自身體排除, 故若於糞便內發現類似錠劑的東西, 無需擔心 3. 使用本品可能產生昏沉 ( 嗜睡 ) 或視覺模糊, 故駕駛或使用機械須小心 Glipizide C 4 Unknown 1 Glipizide 5mg/tab <KGLIPIZ> p p.57 廠商告知藥品商品名變更 Tadalafil B 4 Unknown 1 Cialis 20mg/tab <KTADALA> Erectile dysfunction Starting dose: 10mg, no more than once daily, 1 hr before sexual activity; may increase to 20mg Headache, flushing, abnormal vision, nasal congestion, dyspepsia 1.Onset: min, duration: 36 hrs 2. 若服用本品不建議使用 α 1 adrenergic blocker 3. 本品不建議每日服用 1.Concurrent use of nitrates (eg. nitroglycerin) 2. 嚴重心血管疾病 ( 如 : 近 90 天有心肌梗塞未受控制的心律不整等 ) 第十八次藥政會決議新藥 Cyclophosphamide D 4 Unsafe 1 Syklofosfamid 500mg/vial <CCYCL02> Tadalafil B 4 Unknown 1 Cialis 20mg/tab <KTADALA> Cialis 5mg/tab <KTADAL1> Erectile dysfunction 20mg: Initial 10mg, no more than once daily, 1hr before sexual activity; may increase to 20mg 5mg: 2.5mg qd (at the same time), may increase to 5mg qd base on efficacy and tolerability Headache, flushing, abnormal vision, nasal congestion, dyspepsia Precauti 1. 20mg Onset: min, duration: 36 hrs 2. 若服用本品不建議使用 α 1 adrenergic blocker 3. 易造成輕度或暫時性血壓降低 4. 高劑量 (10mg or 20mg) 適合於性行為前使用, 但不建議每日服用, 故對於需頻繁使用 ( 每週至少二次 ) 的病患, 經醫師評估後可改每天一次最低劑量 (2.5mg or 5mg) 的治療方式 1.Concurrent use of nitrates (eg. nitroglycerin) 2. 嚴重心血管疾病 ( 如 : 近 90 天有心肌梗塞未受控制的心律不整等 ) Cyclophosphamide D 4 Unsafe 1 Syklofosfamid 500mg/vial <CCYCL02>

5 p p.10, 279 疫苗種類 p.82 Leukemias, lymphoma, multiple myeloma IV 40-50mg/kg for 2-5 days or 10-15mg/kg every 7-10 days or 3-5 mg/kg twice weekly Alopecia, gastrointestinal disturbances, hemorrhagic cystitis, leukopenia 需依肝腎功能調整劑量原廠商停產, 更換廠商 Spironolactone C 4 Safe 1 Dosage Form Spiron 25mg/tab <KSPIRON> 原廠商健保價調整為零, 故更換廠商 Midazolam D 4 Unknown 1 Uzolam 5mg/ml/amp <CMIDA01> Midatin 15mg/3ml/amp <CMIDA02> Effective for anesthesia induction sedation Induction of anesthesia Unpremedication IV mg/kg over sec; max: 15mg Premedication IV mg/kg; max: 20mg Preoperative sedation : mg/kg; max:15mg (Uzolam 禁用 ) Hiccoughs, excessive somnolence, headache, respiratory arrest 1. 本品可使用 NS, D5W, D10W 稀釋, 混合比例為 ml 加 15mg midazolam 2. 稀釋後溶液, 室溫下可保存 24 小時或在 5 下存放 3 天 Contraindication 不可與鹼性溶液混合, 在 sodium bicarbonate 中會產生沉澱原廠商停產, 更換廠商適合年齡本院品項 B 型肝炎免疫球蛋白出生 24 小時內 Hepatitis B immune globulin(hbig) HyperHep B S/D B 型肝炎疫苗第一劑出生滿 3-5 天 Hepatitis B vaccine Endoxan 50mg/tab <KCYCLOP> Breast cancer, leukemias, lymphoma, multiple myeloma, mycosis fungoides, neuroblastoma, ovarian cancer, retinoblastoma,nephrotic syndrome in children IV 40-50mg/kg for 2-5 days or 10-15mg/kg every 7-10 days or 3-5 mg/kg twice weekly PO 1-5mg/kg/day Alopecia, gastrointestinal disturbances, hemorrhagic cystitis, leukopenia 1. Further dilutions in D5W or NS is stable for 24hrs at room temperature and 6 days at refrigeration. 2. 需依肝腎功能調整劑量 Spironolactone C 4 Safe 1 Dosage Form Aldactin 25mg/tab <KSPIRON> Midazolam D 4 Unknown 1 Midazo 5mg/ml/amp <CMIDA01> Midatin 15mg/3ml/amp <CMIDA02> Effective for anesthesia induction sedation Induction of anesthesia Unpremedication: IV mg/kg over sec; max: 0.6mg/kg Premedication: IV mg/kg ICU sedation IV mg/kg; max:15mg Preoperative sedation 60 歲以下 : mg/kg 60 歲以上衰弱及慢性病患 : mg/kg, usual dose 2-3mg 小孩 : mg/kg Hiccoughs, excessive somnolence, headache, respiratory arrest 1. 本品可使用 NS, D5W, D10W 稀釋, 混合比例為 ml 加 15mg midazolam 2. 稀釋後溶液, 室溫下可保存 24 小時或在 5 下存放 3 天 Contraindication 不可與鹼性溶液混合, 在 sodium bicarbonate 中會產生沉澱 Dosage Forms < 藥品代碼 > <CHEPAT9> 20mcg/ml/vial

6 第二劑第三劑卡介苗第一劑追加白喉百日咳百日咳破傷風不活化小兒追加麻痺混合疫苗白喉破傷風破傷風百日咳百日咳小兒麻痺症及侵襲性 b 型流行性感冒嗜血桿菌疫苗出生滿一個月出生滿六個月出生 24 小時後國小六年級普查測驗陰性之學童將進入國小就讀且滿 5 歲以上之兒童出生滿二個月出生滿四個月出生滿六個月出生滿 18 個月 Engerix-B <CHEPAT7> Children: 10mcg/dose B.C.G vaccine BCG vaccine Diphtheria, Tetanus, Pertussis and Polio vaccine Adacel - polio DPTa and Polio and Haemophilus influenzae type b conjugate vaccine Pediacel(DTaP5-IPV+Hib) 麻疹疫苗出生滿九個月 Measles vaccine (MV) Rouvax 德國麻疹混合疫苗腮腺炎腮腺炎麻疹出生滿一年三個月 Measles, Mumps and 日本腦炎處方集內文勘誤 p.129 第一劑第二劑第三劑追加出生滿一年三個月隔二週出生滿二年三個月國小一年級 Clobetasone C 5 Unknown 1 Cloba cream 0.05%, 15g/tube <WCLOB02> Very high potency Rubella vaccine MMRII Japanese encephalitis vaccine (JE) Japanese encephalitis vaccine 0.1ml/dose <CBCG1> <C4IN1> <C5IN12 > <CMEASL1> <CMMR> 1ml/amp <CJAPANE> 0.1ml Children(2month~7yrs): /dose 1-3 yrs: 3yrs : 1ml Clobetasone C 5 Unknown 1 Cloba cream 0.05%, 5g/tube <WCLOB02> Very high potency 處方集內文勘誤 p.171 Darbepoetin alfa C 4 Unknown 1 NESP 20mcg/ml/vial <CDARBE1> 處方集內文勘誤 p.228 Levodopa and Benserazide C 4 Unsafe 1 Madopar 250, 1 tab Benserazide 50mg+Levodopa 200mg <KMADOP2> Madopar HBS, 1 tab Benserazide 25mg+Levodopa 100mg <KMADOP3> Darbepoetin alfa C 4 Unknown 1 NESP 20mcg/ml/syringe <CDARBE1> Levodopa and Benserazide C 4 Unsafe 1 Madopar 250, 1 tab Benserazide 50mg+Levodopa 200mg <KMADOP2> Madopar HBS, 1 cap Benserazide 25mg+Levodopa 100mg <KMADOP3> 處方集內文勘誤

2011屏基藥訊第四季

2011屏基藥訊第四季 PINGTUNG CHRISTIAN HOSPITAL 2011 No 16 PharmacyTime... 3... 10... 11 60 08-7368686-1117 2 5 8 11 2 3 72 (Glasgow coma scale) 15 3 9 15 3 8 50-90% 90-100% (CT) (MRI) CT CT X CT (osmotic diuretics) (1)Mannitol