L 8 0 g L ~0 700 g L % 6 00% 1 50% 1 3 NaCl 0 50% NH 4 2 SO % KH 2 PO % CaCO % 0 03% ~ 0 04% 2 24 h 0 02

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1 38 5 Vol 38 No Journal of Jiangxi Normal UniversityNatural Science Sep * Streptomyces lincolnensis % 12 4% Q 93 A Streptomyces lincolnensis 13 50S % 1 50% 1 80% MgSO 4 7H 2 O 0 05% NaCl 0 05% KH 2 PO % KNO % ph 7 0 ~ % α- 1 50% 1 60% 2 00% CaCO % NH 4 2 SO % ph 7 0 ~ % % 6 00% 1 50% NaNO % NH 4 2 SO % NaCl 0 50% KH 2 PO % CaCO % ph ~ L 2 00% 1 50% 3 50% % NaCl 0 40% NH 4 2 SO % KH 2 PO 4 FUS-50LA 0 10% CaCO % 0 03% ~ 0 04% Eclipse E200 Nikon 0 02% ~ 0 03% ph 7 0 ~ WZZ-2S BBG

2 L 8 0 g L ~0 700 g L % 6 00% 1 50% 1 3 NaCl 0 50% NH 4 2 SO % KH 2 PO % CaCO % 0 03% ~ 0 04% 2 24 h 0 02% ~ 0 03% ph 7 0 ~ L 2 00% 6 00% 1 50% NaCl 0 50% NH 4 2 SO % KH 2 PO % CaCO % 0 03% ~ 0 04% 0 02% ~ 0 03% ph 7 0 ~ d 30 ml 250 ml 220 r min d 1 10% 50 ml 250 ml 220 r min d L 10% 15 L μg ml μg 2 d 0 03 ~ 0 05 MPa 350 r min - 1 ml L 15 L 15% μg ml μg ml L 30 8 d 8 6% 0 03 ~ 0 05 MPa 350 r min l0 ml r min min h 168 h 40 h 24 h h 40 h 24 h μg ml μg ml h 8 h μg ml μg ml % 3 2 ~

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504 2014 5 4 1Rajeswaran M Srikrishnan T Crystal and molecular structure and absolute configuration of lincomycin hydrochloride monohydrate J Carbohydr Res 2004 339 12 2111-2115 2Olsovska J Jelinkova

4 Rajeswaran M Srikrishnan T Crystal and molecular structure and absolute configuration of lincomycin hydrochloride monohydrate J Carbohydr Res Olsovska J Jelinkova M Man P High-through put quantification of lincomycin traces in fermentation broth of genetically modified streptomyces spp comparison of ultra per- 6 3 formance liquid chromatography and high-performance liquid chromatography with UV detectionj Journal of Chromatography A Spizek J Rezanka T Lincomycin cultivation of producing 8 6% strains and biosynthesis J Applied Microbiology and Biotechnology % 4Gerasimova S Berezina E Cytomorphological study of lincomycin toxicity J Antibiotiki J

5 J M J J J J D The Study on Production of Lincomycin by Using Liquefied Starch Instead of Saccharified Starch HU Biao-qun 1 WANG Xiao-lan 1* ZHONG Yi-qing 2 XIAO Yong-mei 2 1 College of Life Sciences Jiangxi Normal University Nanchang Jiangxi China 2 Jiangxi Guoyao Pharmaceutical Limited Liability Company Nanchang Jiangxi China AbstractThe study about the effect of liquefied starch instead of saccharified starch on Streptomyces lincolnensis 13 growth and lincomycin fermentation in basic culture medium and carbohydrate supplement was carried out The result showed that fermentation titer increased 8 6% when using liquefied starch instead of saccharified starch in basic culture medium and that fermentation titer increased 12 4% in basic culture medium and carbohydrate supplement Therefore production of lincomycin by using liquefied starch instead of saccharified starch in the basic culture medium and carbohydrate supplement is feasible Key wordsliquefied starchsaccharified starchlincomycinfermentation titer

10期(182-402)

10期(182-402) 中国农学通报 2010,26(10):337-342 Chinese Agricultural Science Bulletin 香蕉栽培管理技术研究概况 1,2 高广平, 易干军 1 1, 魏岳荣 ( 1 广东省农业科学院果树研究所, 广州 510640; 2 江西农业大学, 南昌 330045) 摘要 : 综述