872314B002064M14

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巫悌樊
7 years ago
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3 (OSF) T OSF OSF T T4 T8 B - 58 OSF ( 50 8 ) OSF OSF T B 8 OSF CD4/CD / T T 30 OSF, OSF OSF TGF-β1, TGF-β3 OSF TGF-β2, arecoline,, OSF, arecoline,, TGF-β1 PDGF, arecoline,, OSF TGF-β1 OSF TGF-β1 OSF TGF-β1, arecoline,, OSF PDGF

4 (OSF) T OSF OSF T T4 T8 B - 58 OSF ( 50 8 ) OSF OSF, OSF OSF EIA OSF IL-1β, IL-6, arecoline,, OSF

5 1 ( ) ( ) OSF OSF Anti- B IgG 1/200 Parrafin DAKO CD20 1/400 Cryostat Anti- T IgG 1/50 Parrafin Bio CD43 1/100 Cryostat Genex Anti- IgG 1/50 Parrafin DAKO CD68 1/100 Cryostat 2-2 Anti-CD4 T4 IgG 1/10 Cryostat DAKO Anti-CD8 T8 IgG 1/50 Cryostat DAKO 3 (mm) (mm) (mm) Mean SD Mean SD Mean SD Mean SD T cell B cell Macrophage Mean S.D.(standard deviation) ESL(epithelial surface length) /mm ESA(epithelial surface area) /mm 2 CTL(connective tissue length) /mm CTA(connective tissue area) /mm 2

6 4-2 Mean SD Mean SD Mean SD Mean SD T B M Mean SD Mean SD Mean SD Mean SD T B M Mean SD Mean SD Mean SD Mean SD T B M Mean SD Mean SD Mean SD Mean SD T B M T CTL CTA CD4(+) CD8(+) CD4(+) CD8(+) CD4/CD

7 6-1 Mean SD Mean SD Mean SD Mean SD N H SM SA D SM moderate stage of OSF SA advanced stage of OSF N(normal mucosa) H(hyperkeratosis) S(submucous fibrosis) D(dysplasia) 6-2 T Mean SD Mean SD Mean SD Mean SD N H S M S A D B Mean SD Mean SD Mean SD Mean SD N H S M S A D N - P < 0.05 NS NS S P < NS NS H NS NS - NS D NS NS NS - NS not significant

8 7-2 N - P < 0.05 NS NS S P < NS NS H NS NS - NS D NS NS NS N - P < 0.05 P < 0.05 P < 0.05 S P < NS NS H P < 0.05 NS - NS D P < 0.05 NS NS N - P < 0.05 NS P < 0.05 S P < P < 0.05 NS H NS P < P < 0.05 D P < 0.05 NS P < T N - NS P < 0.05 P < 0.05 S NS - P < 0.05 P < 0.05 H P < 0.05 P < P < 0.05 D P < 0.05 P < 0.05 P < T N - P < 0.05 NS P < 0.05 S P < P < 0.05 NS H NS P < P < 0.05 D P < 0.05 NS P < T N - P < 0.05 NS P < 0.05 S P < NS P < 0.05 H N S P < P < 0.05 D P < 0.05 P < 0.05 P <

9 8-4 T N - P < 0.05 NS P < 0.05 S P < NS P < 0.05 H NS P < P < 0.05 D P < 0.05 P < 0.05 P < B N - NS NS NS S NS - NS NS H NS NS - NS D NS NS NS B N - P<0.05 NS NS S P< P<0.05 NS H NS P< NS D NS NS NS B N - P<0.05 NS NS S P< P<0.05 NS H NS P< NS D NS NS NS B N - P<0.05 NS NS S P< P<0.05 NS H NS P< NS D NS NS NS ( ) E S L E S A C T L C T A SM SM SM SM N P < 0.05 P < 0.05 P < 0.05 P < 0.05 H NS NS NS P < 0.05 D NS NS NS P < 0.05

10 10-2 ( ) E S L E S A C T L C T A SA SA SA SA N P < 0.05 P < 0.05 P < 0.05 P < 0.05 H NS NS NS NS D NS NS NS NS 11-1 ( ) T E S L E S A C T L C T A SM SM SM SM N P < 0.05 P < 0.05 P < 0.05 P < 0.05 H P < 0.05 P < 0.05 P < 0.05 P < 0.05 D P < 0.05 NS NS P < ( ) T E S L E S A C T L C T A SA SA SA SA N NS P < 0.05 NS NS H P < 0.05 P < 0.05 NS NS D P < 0.05 NS P < 0.05 P < ( ) B E S L E S A C T L C T A SM SM SM SM N NS NS P < 0.05 P < 0.05 H NS NS P < 0.05 P < 0.05 D NS NS NS NS 12-2 ( ) B E S L E S A C T L C T A SA SA SA SA N NS P < 0.05 P < 0.05 P < 0.05 H NS NS P < 0.05 P < 0.05 D NS NS NS NS

11 13 24, TGF-β1 TGF-β1 (pg/ml) Control µg/ml arecoline µg/ml arecoline µg/ml arecoline µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml , TGF-β1 TGF-β1 (pg/ml) Control µg/ml arecoline µg/ml arecoline µg/ml arecoline µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml

12 15 24, OSF TGF-β1 TGF-β1 (pg/ml) Control µg/ml arecoline µg/ml arecoline µg/ml arecoline µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml , OSF TGF-β1 TGF-β1 (pg/ml) Control µg/ml arecoline µg/ml arecoline µg/ml arecoline µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml

13 17 24, PDGF PDGF (pg/ml) Control µg/ml arecoline µg/ml arecoline µg/ml arecoline µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml , OSF PDGF PDGF (pg/ml) Control µg/ml arecoline µg/ml arecoline µg/ml arecoline µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml µg/ml

菩提道次第廣論

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